CN1126752C - 神经氨酸化合物 - Google Patents

神经氨酸化合物 Download PDF

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Publication number
CN1126752C
CN1126752C CN97198571A CN97198571A CN1126752C CN 1126752 C CN1126752 C CN 1126752C CN 97198571 A CN97198571 A CN 97198571A CN 97198571 A CN97198571 A CN 97198571A CN 1126752 C CN1126752 C CN 1126752C
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CN
China
Prior art keywords
compound
chf
acid
reaction
tetradeoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN97198571A
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English (en)
Chinese (zh)
Other versions
CN1232461A (zh
Inventor
本田雄
小林庆行
山下诚
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Sankyo Co Ltd
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Sankyo Co Ltd
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Publication of CN1232461A publication Critical patent/CN1232461A/zh
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Publication of CN1126752C publication Critical patent/CN1126752C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Cephalosporin Compounds (AREA)
CN97198571A 1996-08-13 1997-08-12 神经氨酸化合物 Expired - Fee Related CN1126752C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP213456/1996 1996-08-13
JP213456/96 1996-08-13
JP21345696 1996-08-13

Publications (2)

Publication Number Publication Date
CN1232461A CN1232461A (zh) 1999-10-20
CN1126752C true CN1126752C (zh) 2003-11-05

Family

ID=16639524

Family Applications (1)

Application Number Title Priority Date Filing Date
CN97198571A Expired - Fee Related CN1126752C (zh) 1996-08-13 1997-08-12 神经氨酸化合物

Country Status (17)

Country Link
EP (1) EP0934939B1 (enExample)
KR (1) KR100526666B1 (enExample)
CN (1) CN1126752C (enExample)
AT (1) ATE239006T1 (enExample)
AU (1) AU723994B2 (enExample)
CA (1) CA2263336C (enExample)
CZ (1) CZ293041B6 (enExample)
DE (1) DE69721553T2 (enExample)
DK (1) DK0934939T3 (enExample)
ES (1) ES2198002T3 (enExample)
HU (1) HU226130B1 (enExample)
IL (1) IL128358A (enExample)
NO (1) NO319321B1 (enExample)
NZ (1) NZ334101A (enExample)
PT (1) PT934939E (enExample)
RU (1) RU2169145C2 (enExample)
WO (1) WO1998006712A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6518305B1 (en) 1998-04-23 2003-02-11 Abbott Laboratories Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases
US6593314B1 (en) 1999-10-19 2003-07-15 Abbott Laboratories Neuraminidase inhibitors
AU2001252578A1 (en) * 2000-04-25 2001-11-07 Sankyo Company Limited Preventives for influenza
AUPR001000A0 (en) 2000-09-08 2000-10-05 Biota Scientific Management Pty Ltd Novel chemical compounds and their use
WO2002076980A1 (en) * 2001-03-27 2002-10-03 Sankyo Company, Limited Sialic acid derivatives
WO2002092555A1 (en) * 2001-05-11 2002-11-21 Sankyo Company, Limited Sialic acid derivatives
ATE399779T1 (de) * 2001-09-07 2008-07-15 Biota Scient Management Zwischenprodukte für die herstellung von neuraminidase-inhibitor-konjugaten
RU2237470C1 (ru) * 2003-01-27 2004-10-10 Купсин Евгений Вениаминович Комбинированный препарат для устранения симптомов простудных заболеваний и гриппа (варианты)
TWI546306B (zh) * 2007-04-11 2016-08-21 第一三共股份有限公司 神經胺酸衍生物之製造方法
CN102532080A (zh) * 2010-12-29 2012-07-04 中国科学院上海药物研究所 新型唾液酸衍生物及其制备方法,包含该衍生物的药物组合物,以及其用途
EP2678324A1 (en) * 2011-02-24 2014-01-01 Cadila Healthcare Limited Process for the preparation of zanamivir
RU2520836C1 (ru) * 2013-02-27 2014-06-27 Александр Васильевич Иващенко (3r,4r,5s)-4-амино-5-(2,2-дифторацетиламино)-3-(1-этилпропокси)-циклогекс-1-енкарбоновая кислота и ее эфиры, способ их получения и применения
CN117243852A (zh) * 2023-11-01 2023-12-19 华熙生物科技股份有限公司 一种皮肤外用组合物及其用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1057260A (zh) * 1990-04-24 1991-12-25 比奥塔科学管理有限公司 抗病毒化合物
EP0539204A1 (en) * 1991-10-23 1993-04-28 Biota Scientific Management Pty. Ltd. Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha D-neuraminic acid
WO1995020583A1 (en) * 1994-01-27 1995-08-03 Biota Scientific Management Pty. Ltd. Derivatives of 2-deoxy-2,3-dehydro-n-acetylneuraminic acid (dana)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2000786C1 (ru) * 1989-07-25 1993-10-15 Научно-исследовательский институт экспериментальной медицины РАМН Противовирусное средство при гриппозной инфекции
RU2032683C1 (ru) * 1991-07-02 1995-04-10 Андрейчиков Юрий Сергеевич 2-метил-5-метокси-3-метоксалилацетобензофуран, проявляющий противовирусную активность в отношении вируса гриппа типа а и в
RU2030412C1 (ru) * 1992-03-04 1995-03-10 Иркутский институт органической химии СО РАН Способ получения 2-формил-2,5- дибутилтио-2,3- дигидро-4h-пирана

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1057260A (zh) * 1990-04-24 1991-12-25 比奥塔科学管理有限公司 抗病毒化合物
EP0539204A1 (en) * 1991-10-23 1993-04-28 Biota Scientific Management Pty. Ltd. Antiviral 4-substituted-2-deoxy-2,3-didehydro derivatives of alpha D-neuraminic acid
WO1995020583A1 (en) * 1994-01-27 1995-08-03 Biota Scientific Management Pty. Ltd. Derivatives of 2-deoxy-2,3-dehydro-n-acetylneuraminic acid (dana)

Also Published As

Publication number Publication date
AU723994B2 (en) 2000-09-07
NZ334101A (en) 2001-07-27
DE69721553D1 (de) 2003-06-05
EP0934939A1 (en) 1999-08-11
RU2169145C2 (ru) 2001-06-20
KR100526666B1 (ko) 2005-11-08
NO990672D0 (no) 1999-02-12
CN1232461A (zh) 1999-10-20
CZ293041B6 (cs) 2004-01-14
WO1998006712A1 (en) 1998-02-19
IL128358A0 (en) 2000-01-31
DK0934939T3 (da) 2003-07-21
PT934939E (pt) 2003-07-31
HUP9903632A2 (hu) 2001-08-28
CZ36599A3 (cs) 1999-06-16
DE69721553T2 (de) 2004-07-22
ES2198002T3 (es) 2004-01-16
NO319321B1 (no) 2005-07-11
AU3785897A (en) 1998-03-06
EP0934939A4 (enExample) 1999-09-15
IL128358A (en) 2003-04-10
EP0934939B1 (en) 2003-05-02
CA2263336C (en) 2007-03-13
CA2263336A1 (en) 1998-02-19
KR20000029971A (ko) 2000-05-25
HK1022687A1 (en) 2000-08-18
ATE239006T1 (de) 2003-05-15
HU226130B1 (en) 2008-05-28
HUP9903632A3 (en) 2002-04-29
NO990672L (no) 1999-04-13

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