CN112236151A - 用于肿瘤特异性T细胞免疫疗法的IL-13受体α2(IL13RA2)嵌合抗原受体 - Google Patents

用于肿瘤特异性T细胞免疫疗法的IL-13受体α2(IL13RA2)嵌合抗原受体 Download PDF

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CN112236151A
CN112236151A CN201980031550.0A CN201980031550A CN112236151A CN 112236151 A CN112236151 A CN 112236151A CN 201980031550 A CN201980031550 A CN 201980031550A CN 112236151 A CN112236151 A CN 112236151A
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nucleic acid
cells
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贾科莫·坦佩拉
迈克尔·C·延森
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Seattle Childrens Hospital
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CN201980031550.0A 2018-03-14 2019-03-12 用于肿瘤特异性T细胞免疫疗法的IL-13受体α2(IL13RA2)嵌合抗原受体 Pending CN112236151A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862643055P 2018-03-14 2018-03-14
US62/643,055 2018-03-14
PCT/US2019/021823 WO2019178078A1 (en) 2018-03-14 2019-03-12 Il-13 receptor alpha 2 (il13ra2) chimeric antigen receptor for tumor specific t cell immunotherapy

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US (2) US12152079B2 (https=)
EP (1) EP3765041A4 (https=)
JP (2) JP7438123B2 (https=)
KR (1) KR102805003B1 (https=)
CN (1) CN112236151A (https=)
AU (1) AU2019234573B2 (https=)
BR (1) BR112020018670A2 (https=)
CA (1) CA3093810A1 (https=)
EA (1) EA202091982A1 (https=)
IL (2) IL277267B2 (https=)
MX (1) MX2020009463A (https=)
SG (1) SG11202008795SA (https=)
WO (1) WO2019178078A1 (https=)

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CN114014941A (zh) * 2022-01-10 2022-02-08 卡瑞济(北京)生命科技有限公司 靶向IL13Rα2的嵌合抗原受体及其用途
CN114409782A (zh) * 2021-12-29 2022-04-29 华道(上海)生物医药有限公司 一种抗IL13Ra2的纳米抗体及其应用
CN114990069A (zh) * 2022-05-17 2022-09-02 郑州大学第一附属医院 一种过表达slc43a2的嵌合抗原受体t细胞的制备方法和应用
CN115246883A (zh) * 2021-02-02 2022-10-28 浙江理工大学 一种抗人源IL13Ra2鲨鱼单域抗体或其抗原结合片段和应用
WO2023274380A1 (zh) * 2021-07-01 2023-01-05 宁波茂行生物医药科技有限公司 靶向IL13Rα2的通用型CAR-T细胞及其制备方法和应用
CN115960257A (zh) * 2022-09-29 2023-04-14 卡瑞济(北京)生命科技有限公司 靶向IL13Rα2的经优化的嵌合抗原受体及其用途
WO2024041650A1 (en) * 2022-08-25 2024-02-29 Nanjing Legend Biotech Co., Ltd. Chimeric antigen receptors targeting interleukin 13 receptor subunit alpha 2 and methods of use thereof

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SG11202008926RA (en) 2018-03-14 2020-10-29 Seattle Childrens Hospital Dba Seattle Childrens Res Inst Il-13 receptor alpha 2 targeted, zetakine directed t cell immunotherapy
EP3842461A1 (en) * 2019-12-23 2021-06-30 Albert-Ludwigs-Universität Freiburg Chimeric antigen receptors that bind to prostate specific membrane antigen
KR20230022411A (ko) * 2020-05-12 2023-02-15 라이엘 이뮤노파마, 인크. 키메라 항원 수용체 스페이서
AU2022227686A1 (en) 2021-02-25 2023-07-27 Lyell Immunopharma, Inc. Ror1 targeting chimeric antigen receptor
JP2024514101A (ja) * 2021-04-01 2024-03-28 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ Ｉｌ－１３ｒａ２キメラ抗原受容体および使用方法
WO2023138666A1 (en) * 2022-01-19 2023-07-27 Utc Therapeutics (Shanghai) Co., Ltd. Circular rna and use thereof
CN114805581B (zh) * 2022-06-29 2022-10-14 上海优替济生生物医药有限公司 靶向il13ra2的抗体、嵌合抗原受体及其用途
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof
WO2025154925A1 (ko) * 2024-01-18 2025-07-24 엑셀라몰(주) IL13Ra2에 결합하는 폴리펩타이드 약물 접합체 및 이의 용도

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TWI805109B (zh) * 2014-08-28 2023-06-11 美商奇諾治療有限公司 對cd19具專一性之抗體及嵌合抗原受體
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CN115246883A (zh) * 2021-02-02 2022-10-28 浙江理工大学 一种抗人源IL13Ra2鲨鱼单域抗体或其抗原结合片段和应用
CN115768445A (zh) * 2021-07-01 2023-03-07 宁波茂行生物医药科技有限公司 靶向IL13Rα2的通用型CAR-T细胞及其制备方法和应用
WO2023274380A1 (zh) * 2021-07-01 2023-01-05 宁波茂行生物医药科技有限公司 靶向IL13Rα2的通用型CAR-T细胞及其制备方法和应用
CN116514982A (zh) * 2021-12-29 2023-08-01 华道(上海)生物医药有限公司 一种抗IL13Ra2的纳米抗体及其应用
CN114409782A (zh) * 2021-12-29 2022-04-29 华道(上海)生物医药有限公司 一种抗IL13Ra2的纳米抗体及其应用
CN114409782B (zh) * 2021-12-29 2023-06-30 华道(上海)生物医药有限公司 一种抗IL13Ra2的纳米抗体及其应用
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CN116514982B (zh) * 2021-12-29 2023-12-19 华道(上海)生物医药有限公司 一种抗IL13Ra2的纳米抗体及其应用
CN114014941A (zh) * 2022-01-10 2022-02-08 卡瑞济(北京)生命科技有限公司 靶向IL13Rα2的嵌合抗原受体及其用途
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CN115960257A (zh) * 2022-09-29 2023-04-14 卡瑞济(北京)生命科技有限公司 靶向IL13Rα2的经优化的嵌合抗原受体及其用途
CN115960257B (zh) * 2022-09-29 2023-10-27 卡瑞济(北京)生命科技有限公司 靶向IL13Rα2的经优化的嵌合抗原受体及其用途
WO2024066026A1 (zh) * 2022-09-29 2024-04-04 卡瑞济(北京)生命科技有限公司 靶向IL13Rα2的经优化的嵌合抗原受体及其用途

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