|
US5948768A
(en)
*
|
1995-04-13 |
1999-09-07 |
Milkhaus Laboratory |
Treatment of otitis media by sublingual administration of DNA
|
|
US6096721A
(en)
*
|
1995-04-13 |
2000-08-01 |
Milkhaus Laboratory, Inc. |
Method for treating mucositis by sublingual administration of DNA
|
|
CA2192674C
(en)
*
|
1995-04-13 |
2001-02-13 |
John Mcmichael |
Methods for treating respiratory disease
|
|
US5635160A
(en)
|
1995-06-07 |
1997-06-03 |
The University Of North Carolina At Chapel Hill |
Dinucleotides useful for the treatment of cystic fibrosis and for hydrating mucus secretions
|
|
US5628984A
(en)
*
|
1995-07-31 |
1997-05-13 |
University Of North Carolina At Chapel Hill |
Method of detecting lung disease
|
|
US6319908B1
(en)
|
1996-07-03 |
2001-11-20 |
Inspire Pharmaceuticals, Inc. |
Method for large-scale production of di(uridine 5′-tetraphosphate) and salts thereof
|
|
US5968913A
(en)
*
|
1996-07-03 |
1999-10-19 |
Inspire Pharmaceuticals, Inc. |
Pharmaceutical compositions of uridine triphosphate
|
|
US5763447C1
(en)
|
1996-07-23 |
2002-05-07 |
Inspire Pharmaceuticals |
Method of preventing or treating pneumonia in immobilized patients with uridine triphosphates and related compounds
|
|
US6159952A
(en)
*
|
1996-11-07 |
2000-12-12 |
Inspire Pharmaceuticals, Inc. |
Method of treating bronchitis with uridine triphosphate and related compounds
|
|
US6998121B2
(en)
|
2003-01-23 |
2006-02-14 |
Milkhaus Laboratory, Inc. |
Method of treatment of connective tissue disorders by administration of streptolysin O
|
|
TW593331B
(en)
|
1997-07-25 |
2004-06-21 |
Inspire Pharmaceuticals Inc |
Method for large-scale production of di(uridine 5')-tetraphosphate and salts thereof
|
|
US6872710B2
(en)
*
|
1997-07-25 |
2005-03-29 |
Inspire Pharmaceuticals, Inc. |
Di(uridine 5′)-tetraphosphate and salts thereof
|
|
AU747196B2
(en)
|
1997-07-25 |
2002-05-09 |
Merck Sharp & Dohme Corp. |
Method for large-scale production of di(uridine 5'-tetraphosphate) and salts thereof
|
|
BR9811612A
(pt)
*
|
1997-08-29 |
2000-08-08 |
Univ North Carolina |
Uso de 5' -difosfato de uridina e similares para tratamento de doenças pulmonares
|
|
NZ512383A
(en)
*
|
1998-12-22 |
2003-05-30 |
Univ North Carolina |
Use of osmotic agents in the treatment of airway diseases and for the delivery of airway drugs
|
|
US6926911B1
(en)
|
1998-12-22 |
2005-08-09 |
The University Of North Carolina At Chapel Hill |
Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs
|
|
KR20010114214A
(ko)
|
1999-02-26 |
2001-12-31 |
인스파이어 파마슈티컬스 인코퍼레이티드 |
우리딘, 아데닌 및 시티딘 디포스페이트 및 그의 유사체에의한 점막수화 촉진방법
|
|
EP1190249A2
(en)
*
|
1999-06-08 |
2002-03-27 |
University Of Iowa Research Foundation |
Compounds and methods to enhance raav transduction
|
|
US7241447B1
(en)
*
|
1999-10-07 |
2007-07-10 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors and uses thereof
|
|
US7115585B2
(en)
*
|
2000-08-21 |
2006-10-03 |
Inspire Pharmaceuticals, Inc. |
Compositions for treating epithelial and retinal tissue diseases
|
|
US7018985B1
(en)
|
2000-08-21 |
2006-03-28 |
Inspire Pharmaceuticals, Inc. |
Composition and method for inhibiting platelet aggregation
|
|
US7452870B2
(en)
*
|
2000-08-21 |
2008-11-18 |
Inspire Pharmaceuticals, Inc. |
Drug-eluting stents coated with P2Y12 receptor antagonist compound
|
|
JP2005508297A
(ja)
|
2001-06-25 |
2005-03-31 |
インスパイアー ファーマシューティカルズ,インコーポレイティド |
P2yプリン受容体作用物質による関節潤滑
|
|
JP3823162B2
(ja)
*
|
2001-07-31 |
2006-09-20 |
株式会社エイアンドティー |
臨床検査分析装置、臨床検査分析方法および臨床検査分析プログラム
|
|
KR20050043761A
(ko)
*
|
2001-11-06 |
2005-05-11 |
인스파이어 파마슈티컬스 인코퍼레이티드 |
염증성 질환의 치료 또는 예방 방법
|
|
US20060196365A1
(en)
*
|
2001-12-11 |
2006-09-07 |
Garman Michael H |
Combined water cooler and hot beverage maker
|
|
US6858615B2
(en)
|
2002-02-19 |
2005-02-22 |
Parion Sciences, Inc. |
Phenyl guanidine sodium channel blockers
|
|
US7435724B2
(en)
*
|
2002-02-27 |
2008-10-14 |
Inspire Pharmaceutical, Inc. |
Degradation-resistant mononucleoside phosphate compounds
|
|
CA2483917C
(en)
|
2002-05-02 |
2013-07-30 |
President And Fellows Of Harvard College |
Formulations limiting spread of pulmonary infections
|
|
US20050220720A1
(en)
*
|
2002-05-02 |
2005-10-06 |
David Edwards |
Formulations limiting spread of pulmonary infections
|
|
US7629312B2
(en)
|
2003-01-23 |
2009-12-08 |
Milkhaus Laboratory, Inc. |
Method of treatment of tendonitis by administration of streptolysin O
|
|
US20050095225A1
(en)
*
|
2003-03-31 |
2005-05-05 |
Engelhardt John F. |
Compounds and methods for pharmico-gene therapy of epithelial sodium channel associated disorders
|
|
BRPI0411900B8
(pt)
|
2003-06-26 |
2021-05-25 |
Biotron Ltd |
compostos e composições farmacêuticas compreendendo os mesmos
|
|
US20090253714A1
(en)
*
|
2003-08-20 |
2009-10-08 |
Johnson Michael R |
Methods of reducing risk of infection from pathogens
|
|
US7745442B2
(en)
|
2003-08-20 |
2010-06-29 |
Parion Sciences, Inc. |
Methods of reducing risk of infection from pathogens
|
|
WO2005051296A2
(en)
*
|
2003-11-24 |
2005-06-09 |
University Of North Carolina At Chapel Hill |
Fused ring dicationic anti-protozoan agents and their prodrugs
|
|
US20050207983A1
(en)
*
|
2004-03-05 |
2005-09-22 |
Pulmatrix, Inc. |
Formulations decreasing particle exhalation
|
|
WO2005086754A2
(en)
*
|
2004-03-08 |
2005-09-22 |
Georgia State University Research Foundation, Inc. |
Dicationic compounds for activity against trichomonas vaginalis
|
|
US20070099968A1
(en)
*
|
2004-06-26 |
2007-05-03 |
Biotron Limited |
Antiviral compounds and methods
|
|
GB0417886D0
(en)
*
|
2004-08-11 |
2004-09-15 |
Univ Cardiff |
Method and means for enhanced pulmonary delivery
|
|
WO2006096757A2
(en)
|
2005-03-07 |
2006-09-14 |
The University Of North Carolina At Chapel Hill |
Inhibitors of reca activities for control of antibiotic-resistant bacterial pathogens
|
|
AU2006201739A1
(en)
*
|
2005-05-05 |
2006-11-23 |
The University Of North Carolina At Chapel Hill |
Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles
|
|
EP2308469A1
(en)
*
|
2005-05-18 |
2011-04-13 |
Pulmatrix, Inc. |
Formulations for alteration of biophysical properties of mucosal lining
|
|
US7964619B2
(en)
|
2005-06-03 |
2011-06-21 |
The University Of North Carolina At Chapel Hill |
Teraryl components as antiparasitic agents
|
|
AU2006202083A1
(en)
*
|
2005-06-03 |
2006-12-21 |
Reto Brun |
Linear dicationic terphenyls and their aza analogues as antiparasitic agents
|
|
US20100249175A1
(en)
*
|
2005-12-02 |
2010-09-30 |
Wilson W David |
Dicationic compounds which selectively recognize G-quadruplex DNA
|
|
WO2007127464A2
(en)
*
|
2006-04-28 |
2007-11-08 |
University Of Iowa Research Foundation |
Methods and compounds to modulate parvovirus transduction of mammalian cells or to alter virus infection, method to identify a viral receptor or co-receptor
|
|
US20080260863A1
(en)
*
|
2007-04-20 |
2008-10-23 |
Pre Holding, Inc. |
Compositions for mucociliary clearance and methods for administering same
|
|
US8088385B2
(en)
|
2007-06-18 |
2012-01-03 |
University Of Louisville Research Foundation Inc. |
PFKB3 inhibitor for the treatment of a proliferative cancer
|
|
US20100280098A1
(en)
*
|
2007-10-05 |
2010-11-04 |
Juliano Rudolph L |
Receptor targeted oligonucleotides
|
|
WO2009049159A1
(en)
|
2007-10-10 |
2009-04-16 |
Parion Sciences, Inc. |
Delivering osmolytes by nasal cannula
|
|
WO2009051796A2
(en)
*
|
2007-10-17 |
2009-04-23 |
The University Of North Carolina At Chapel Hill |
2,5-diaryl selenophene compounds, aza 2,5-diaryl thiophene compounds, and their prodrugs as antiprotozoal agents
|
|
AU2009234156A1
(en)
|
2008-04-09 |
2009-10-15 |
The University Of North Carolina At Chapel Hill |
Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation
|
|
US20110224227A1
(en)
*
|
2008-10-01 |
2011-09-15 |
Sharpless Norman E |
Hematopoietic protection against chemotherapeutic compounds using selective cyclin-dependent kinase 4/6 inhibitors
|
|
EP2341906A4
(en)
|
2008-10-01 |
2012-06-13 |
Univ North Carolina |
HEMATOPOIETIC PROTECTION AGAINST IONIZATION RADIATION USING SELF-ACTIVE CYCLINE-DEPENDENT KINASE-4/6-HEMMER
|
|
EP2410981B2
(en)
|
2009-03-26 |
2020-02-26 |
Pulmatrix Operating Company, Inc. |
Dry powder formulations and methods for treating pulmonary diseases
|
|
US20120100100A1
(en)
|
2009-05-13 |
2012-04-26 |
Sharpless Norman E |
Cyclin dependent kinase inhibitors and methods of use
|
|
ES2824842T3
(es)
|
2009-07-13 |
2021-05-13 |
Patheon Api Services Inc |
Síntesis de prostanoides
|
|
CA2768582C
(en)
|
2009-07-24 |
2017-02-14 |
University Of Tennessee Research Foundation |
Spectinamides as anti-tuberculosis agents
|
|
CA2770565A1
(en)
*
|
2009-08-10 |
2011-02-17 |
P2-Science Aps |
Utp for the diagnosis of stenoses and other conditions of restricted blood flow
|
|
JP5922111B2
(ja)
*
|
2010-06-23 |
2016-05-24 |
ピーツー−サイエンス・エペイエス |
充血剤注入と同時に血圧測定を行う診断目的の動脈用複合カテーテル
|
|
CA2809666C
(en)
|
2010-08-30 |
2020-09-22 |
Michael M. Lipp |
Dry powder formulations and methods for treating pulmonary diseases
|
|
WO2012030647A1
(en)
|
2010-08-30 |
2012-03-08 |
Pulmatrix, Inc. |
Treatment of cystic fibrosis using calcium lactate, leucine and sodium chloride in a respiraple dry powder
|
|
WO2012044736A1
(en)
|
2010-09-29 |
2012-04-05 |
Pulmatrix, Inc. |
Monovalent metal cation dry powders for inhalation
|
|
PT2621488T
(pt)
|
2010-09-29 |
2019-02-12 |
Pulmatrix Operating Co Inc |
Pós secos catiónicos
|
|
CN103501789A
(zh)
|
2010-11-17 |
2014-01-08 |
北卡罗来纳大学查珀尔希尔分校 |
通过抑制增殖性激酶cdk4和cdk6保护肾组织免于局部缺血
|
|
EP2717855A4
(en)
|
2011-06-07 |
2014-11-12 |
Parion Sciences Inc |
PROCESSING METHODS
|
|
US8945605B2
(en)
*
|
2011-06-07 |
2015-02-03 |
Parion Sciences, Inc. |
Aerosol delivery systems, compositions and methods
|
|
AR086745A1
(es)
|
2011-06-27 |
2014-01-22 |
Parion Sciences Inc |
3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
|
|
EP2819672A1
(en)
|
2012-02-29 |
2015-01-07 |
Pulmatrix, Inc. |
Inhalable dry powders
|
|
US9833207B2
(en)
|
2012-08-08 |
2017-12-05 |
William Harrison Zurn |
Analysis and clearing module, system and method
|
|
CA2895512C
(en)
|
2012-12-17 |
2021-10-19 |
Parion Sciences, Inc. |
Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration
|
|
AU2013363215B2
(en)
|
2012-12-17 |
2018-03-01 |
Parion Sciences, Inc. |
3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds
|
|
US9962533B2
(en)
|
2013-02-14 |
2018-05-08 |
William Harrison Zurn |
Module for treatment of medical conditions; system for making module and methods of making module
|
|
EP2967050A4
(en)
|
2013-03-15 |
2016-09-28 |
G1 Therapeutics Inc |
HIGH-ACTIVE ANTINEOPLASTIC AND ANTIPROLIFERATIVE AGENTS
|
|
US9464092B2
(en)
|
2013-03-15 |
2016-10-11 |
G1 Therapeutics, Inc. |
Transient protection of normal cells during chemotherapy
|
|
CA2907566C
(en)
|
2013-04-01 |
2023-08-22 |
Pulmatrix, Inc. |
Tiotropium dry powders
|
|
BR112016006951B1
(pt)
|
2013-09-30 |
2022-10-04 |
Patheon Api Services Inc |
Novas vias de síntese para prostaglandinas e intermediários de prostaglandina com o uso de metátese
|
|
US9102633B2
(en)
|
2013-12-13 |
2015-08-11 |
Parion Sciences, Inc. |
Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
|
|
WO2015161285A1
(en)
|
2014-04-17 |
2015-10-22 |
G1 Therapeutics, Inc. |
Tricyclic lactams for use in the protection of hematopoietic stem and progenitor cells against ionizing radiation
|
|
WO2016040848A1
(en)
|
2014-09-12 |
2016-03-17 |
G1 Therapeutics, Inc. |
Treatment of rb-negative tumors using topoisomerase inhibitors in combination with cyclin dependent kinase 4/6 inhibitors
|
|
EP3191098A4
(en)
|
2014-09-12 |
2018-04-25 |
G1 Therapeutics, Inc. |
Combinations and dosing regimes to treat rb-positive tumors
|
|
CN104306028B
(zh)
*
|
2014-09-26 |
2016-08-17 |
张清玲 |
一种用于呼吸道细菌16S rRNA基因序列检测的痰液收集方法
|
|
AR106018A1
(es)
|
2015-08-26 |
2017-12-06 |
Achillion Pharmaceuticals Inc |
Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
|
|
WO2017035409A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders
|
|
WO2017035405A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Amino compounds for treatment of immune and inflammatory disorders
|
|
WO2017035401A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Amide compounds for treatment of immune and inflammatory disorders
|
|
US11702672B2
(en)
|
2016-02-08 |
2023-07-18 |
University Of Iowa Research Foundation |
Methods to produce chimeric adeno-associated virus/bocavirus parvovirus
|
|
CA3198936A1
(en)
|
2016-03-07 |
2017-09-14 |
University Of Iowa Research Foundation |
Aav-mediated expression using a synthetic promoter and enhancer
|
|
US12173305B2
(en)
|
2016-05-26 |
2024-12-24 |
University Of Iowa Research Foundation |
cis and trans requirements for terminal resolution of human bocavirus 1
|
|
AU2017290748A1
(en)
|
2016-07-01 |
2019-01-17 |
G1 Therapeutics, Inc. |
Pyrimidine-based antiproliferative agents
|
|
US10413583B2
(en)
|
2016-11-30 |
2019-09-17 |
The University Of Chicago |
Synthetic substrates for enzymes that catalyze reactions of modified cysteines and related methods
|
|
WO2018132747A1
(en)
|
2017-01-13 |
2018-07-19 |
University Of Iowa Research Foundation |
Bocaparvovirus small noncoding rna and uses thereof
|
|
CA3053818A1
(en)
|
2017-03-01 |
2018-09-07 |
Achillion Pharmaceuticals, Inc. |
Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders
|
|
WO2018160891A1
(en)
|
2017-03-01 |
2018-09-07 |
Achillion Pharmaceutical, Inc. |
Pharmaceutical compounds for treatment of medical disorders
|
|
WO2019028284A1
(en)
|
2017-08-02 |
2019-02-07 |
Achillion Pharmaceuticals, Inc. |
THERAPEUTIC REGIMES FOR THE TREATMENT OF NOCTURNAL PAROXYSTIC HEMOGLOBINURIA
|
|
GB2604314A
(en)
*
|
2017-09-22 |
2022-09-07 |
Nerudia Ltd |
Device, system and method
|
|
US11439608B2
(en)
|
2017-09-25 |
2022-09-13 |
Qun Lu |
Roles of modulators of intersectin-CDC42 signaling in Alzheimer's disease
|
|
US11541120B2
(en)
|
2017-12-05 |
2023-01-03 |
Anthos Partners, Lp |
Phosphonium-based ionic drug conjugates
|
|
US11814391B2
(en)
|
2018-09-06 |
2023-11-14 |
Achillion Pharmaceuticals, Inc. |
Macrocyclic compounds for the treatment of medical disorders
|
|
KR20210057086A
(ko)
|
2018-09-06 |
2021-05-20 |
아칠리온 파르마세우티칼스 인코포레이티드 |
다니코판의 형태체 형태
|
|
EP3856164B1
(en)
|
2018-09-25 |
2024-08-07 |
Achillion Pharmaceuticals, Inc. |
Morphic forms of complement factor d inhibitors
|
|
MX2021007329A
(es)
|
2018-12-17 |
2021-09-21 |
Achillion Pharmaceuticals Inc |
Dosificacion dirigida para el tratamiento de trastornos mediados por el complemento.
|
|
KR20220004024A
(ko)
|
2019-03-22 |
2022-01-11 |
아칠리온 파르마세우티칼스 인코포레이티드 |
보체 매개 장애의 치료를 위한 약제학적 조성물
|
|
CN115698014B
(zh)
|
2020-05-19 |
2025-07-29 |
法码科思莫斯控股有限公司 |
用于治疗医学病症的细胞周期蛋白依赖性激酶抑制化合物
|
|
US10988479B1
(en)
|
2020-06-15 |
2021-04-27 |
G1 Therapeutics, Inc. |
Morphic forms of trilaciclib and methods of manufacture thereof
|