CN112022763A

CN112022763A - Liquid foundation and preparation method thereof

Info

Publication number: CN112022763A
Application number: CN202010903574.5A
Authority: CN
Inventors: 王烈城
Original assignee: Guangzhou Epeilan Cosmetics Co ltd
Current assignee: Guangzhou Epeilan Cosmetics Co ltd
Priority date: 2020-09-01
Filing date: 2020-09-01
Publication date: 2020-12-04

Abstract

The application relates to a liquid foundation and a preparation method thereof, which comprises the following steps: angelica acutiloba Kitagawa extract; ganoderma lucidum stem extract; an extract of Astragalus membranaceus; an emulsifier; a colorant; a solvent; also relates to a preparation method of the liquid foundation, which comprises the following steps: step 1, pretreating raw materials; step 1-1, heating a solvent to 82-88 ℃, and preserving heat for 8-12 minutes at the temperature of 82-88 ℃ to obtain a first processed object; step 1-2, mixing and heating an emulsifier and a coloring agent to 82-88 ℃, uniformly stirring, and keeping the temperature at 82-88 ℃ for 8-12 minutes to obtain a second pretreatment substance; step 2; mixing the first treated matter and the second pre-treated matter, stirring, and maintaining at 82-88 deg.c for 28-32 min to obtain the second treated matter; and 3, cooling the second processed product to 43-47 ℃, adding the angelica sinensis extract, the ganoderma lucidum stem extract and the astragalus membranaceus extract, and uniformly stirring to obtain a foundation solution. The present application has the effect of improving the multiple anti-aging capacity of the skin.

Description

Liquid foundation and preparation method thereof

Technical Field

The application relates to the field of cosmetics, in particular to a foundation liquid and a preparation method thereof.

Background

At present, with the improvement of living standard of people, people pursue beauty more and more, cosmetics become essential products of people, especially women, foundation liquid is liquid foundation, the foundation liquid is light and natural when being coated on the face, the makeup is lasting and difficult to remove, the foundation liquid is the best choice of daily makeup, the foundation liquid can cover flaws and can preserve moisture and nourish skin, but the natural moisture-preserving capability and immunity of the skin are reduced easily by using the cosmetics for a long time, so that the skin is aged, therefore, people pay more and more attention to the effects of skin care and skin care of the cosmetics, and especially pay more and more attention to the foundation liquid with the anti-aging effect.

The existing anti-aging foundation cream mainly comprises components with different effects, and the aim of relieving the skin cell aging is achieved by preventing and slowing down the skin aging from different directions.

In view of the above-mentioned related technologies, the inventor believes that the anti-aging active ingredients in foundation liquid usually adopt plant extracts, one extract usually can only produce one to two anti-aging effects, and wants to better resist skin aging and improve skin immunity, and needs the cooperation of multiple plant extracts, but when multiple plant extracts are mutually cooperated, there may be the case that the drug effects are mutually washed out or mutually offset, and the foundation liquid which slows down skin aging from different aspects is not many in the market, which is difficult to meet the demand.

Disclosure of Invention

In order to improve the multiple anti-aging capability of the skin, the application provides a foundation liquid and a preparation method thereof.

In a first aspect, the present application provides a foundation solution, which adopts the following technical scheme:

a foundation solution mainly comprises the following components in percentage by mass:

0.05 to 0.21 percent of angelica sinensis extract;

0.06% -0.22% of ganoderma lucidum stem extract;

0.25 to 0.45 percent of astragalus membranaceus extract;

2.5 to 5.5 percent of emulsifier;

5.95 to 10.65 percent of colorant;

the balance of solvent;

the total mass percentage is 100 percent.

By adopting the technical scheme, the angelica sinensis extract has good superoxide dismutase (SOD) activity by adding the angelica sinensis extract, so that the angelica sinensis extract can better inhibit membrane lipid peroxidation caused by superoxide radicals, thereby increasing the capacity of antagonizing free radicals of skin tissues, delaying skin aging, and improving gray complexion or sore swelling caused by free radical retardation. By adding the ganoderma lucidum stem extract, the ganoderma lucidum polypeptide content in the ganoderma lucidum stem extract is rich, the ganoderma lucidum polypeptide can be combined with skin epithelial cells through the cuticle, the living environment of the skin cells is improved, and the metabolism is promoted, so that the aim of moistening the skin is fulfilled, the ganoderma lucidum stem extract can inhibit the activity of tyrosinase, the generation of pigments is reduced, the effects of improving dark skin color and repairing and tendering the skin are achieved, the cell aging is delayed, the skin is made to be tight and fine, and the anti-aging effect is better. By adding the astragalus membranaceus extract which contains important active ingredient astragalus saponin, harmful free radicals in the skin can be effectively removed, the astragalus membranaceus extract has a good antioxidant effect, and the content of aging metabolite Lipid Peroxide (LPO) and Lipofuscin (LF) is reduced, so that the metabolism of the skin is enhanced, the absorption of nutrients is promoted, wrinkles are effectively prevented, the skin is moistened, and a good effect of delaying skin aging is achieved. By adding the angelica sinensis extract, the ganoderma lucidum stem extract and the astragalus membranaceus extract, the ganoderma lucidum stem extract relieves the DPPH (dehydroepiandrosterone PH) free radical clearance of the angelica sinensis extract on the astragalus membranaceus extract and the inhibition effect of the ganoderma lucidum stem extract on metabolism, relieves the superoxide radical clearance of the astragalus membranaceus extract on the angelica sinensis extract and strengthens the inhibition effect of skin barriers, and the angelica sinensis extract further enhances the capability of skin tissues in antagonizing free radicals, so that wrinkles are effectively prevented, the skin is moistened, and the foundation fluid has multiple anti-aging effects and is good in effect. By adding the emulsifier, the effect of forming a uniform and stable dispersion system by each component in the solvent is better, the emulsified state of each component is more stable, the smearing effect of the foundation liquid is better, and the stability of the foundation liquid is higher.

Preferably, the composition also comprises the following components in percentage by mass:

0.4 to 0.9 percent of liquorice extract;

centella asiatica extract 0.3% -0.8%;

0.15 to 0.55 percent of radix scutellariae extract;

0.2 to 0.5 percent of white atractylodes rhizome extract;

0.2 to 0.6 percent of divaricate saposhnikovia root extract;

0.15 to 0.75 percent of magnesium stearate.

By adopting the technical scheme, the liquorice extract can enhance the disease resistance of the skin, can effectively inhibit the activation of tyrosinase, prevent the generation of melanin, has the whitening effect, and can maintain the emulsified state of the foundation liquid for a long time and prevent oxidative deterioration. By adding the centella asiatica extract, the centella asiatica extract can treat skin ulcer and promote protein regeneration, so that the skin is smoother. The radix scutellariae extract has the inhibiting effect on various skin pathogenic fungi and can absorb ultraviolet rays, and has certain repairing effect on sunburned skin, so that the effect of resisting aging of the skin is better. The white atractylodes rhizome extract is added, and contains a plurality of whitening components such as alpha-humulene, beta-elemene, alpha-curcumene, 3 beta-acetoxy atractylone and the like, so that the white atractylodes rhizome extract has the effects of whitening and tendering skin. By adding the radix sileris extract, the radix sileris extract has the functions of eliminating various free radicals, has better oxidation resistance and certain inhibiting effect on melanin, and can whiten the skin. By adding the magnesium stearate, the magnesium stearate has flowing anti-adhesion property, and can lubricate the damaged part of the skin, so that the skin can be helped to absorb the energy of corresponding substances better, the healing and the repairing of the skin are accelerated, and the elasticity of the skin is effectively improved. Through the matching of the components, the components have certain relieving effect on skin after being added, and can play respective effects to a greater extent, so that the repairing, nursing and anti-aging effects of the foundation liquid are better.

Preferably, the emulsifier is one or more of cetyl PEG/PPG-10/1 polydimethylsiloxane, polyglycerol-3 diisostearate, hydrogenated lecithin and glycerol stearate citrate.

By adding cetyl PEG/PPG-10/1 polydimethylsiloxane and polyglycerol-3 diisostearate, the surface tension between various constituent phases in the emulsion can be improved, so that each component forms a uniform and stable dispersion system in a solvent, is miscible and emulsifiable with various oils, and simultaneously has the advantages of improving the spreadability of a color cosmetic product, improving the dispersibility of a colorant, preventing the migration of pigments and keeping the foundation liquid in a relatively stable liquid state.

22% -27.5% of humectant; the humectant is one or more of polydimethylsiloxane, glycerol and propylene glycol.

By adopting the technical scheme, the polydimethylsiloxane is added, has lubricating property, has better air permeability while helping the skin to have better moisturizing effect, keeps the skin in a moisturizing state for a longer time, and is favorable for keeping the skin in a healthy state. By adding glycerin, glycerin has a good moisturizing effect and is beneficial to keeping the skin in a moist state. By adding the propylene glycol, the propylene glycol has the effect of promoting the skin absorption and can lock water to achieve the effect of moisturizing, so that the water locking capacity of the skin is improved.

Preferably, the humectant comprises the following components in percentage by mass:

9% -10.5% of polydimethylsiloxane;

7.5% -10% of glycerol;

5.5 to 7 percent of propylene glycol.

By adopting the technical scheme, one or more of polydimethylsiloxane, glycerol and propylene glycol are usually compounded, so that the foundation fluid has a good moisturizing effect, the moisture of the skin is not easy to lose, the capability of the skin to absorb corresponding substances is facilitated, and the self-repairing capability of the skin is improved.

20% -27% of an emollient; the emollient is one or more of aluminum hydroxide, cyclomethicone, isononyl isononanoate and octyl methicone.

By adopting the technical scheme, the aluminum hydroxide can be used as a film on the colorant by adding the aluminum hydroxide, so that the colorant can be prevented from caking, the foundation liquid can be smeared more uniformly, and meanwhile, the aluminum hydroxide can also form a refraction layer to help the skin to reflect UV rays and improve the anti-aging capability of the skin. By adding the cyclomethicone, the cyclomethicone has lower surface tension, better spreadability and lubricity, and the skin after being smeared has dry and comfortable effect. By adding isononyl isononanoate, the isononyl isononanoate has a unique multi-methyl branched chain structure and good compatibility with silicone oil, can solve the problem of low-temperature precipitation of the silicone oil, and has good dispersing ability for a colorant, so that the skin feel is fresh and cool after being smeared and greasy feeling is not easy to generate. By adding octyl polymethylsiloxane, the octyl polymethylsiloxane has more hydrophobic octyl, so that the octyl polymethylsiloxane has better adaptability to the skin, and the effects of assisting the skin to be lubricated and softening after the foundation liquid is smeared are better.

Preferably, the emollient comprises the following components in percentage by mass:

3.5 to 5 percent of aluminum hydroxide;

9% -10.5% of cyclopolydimethylsiloxane;

isononyl isononanoate 6% -8.5%;

1.5 to 3 percent of octyl polymethylsiloxane.

By adopting the technical scheme, through the matching of the components, the dispersing effect on the colorant is better, the foundation liquid can be more uniformly applied, the lipid content of the upper layer of the skin is improved, the excessive degreasing and drying of the skin are prevented, and the skin is kept soft, smooth and elastic.

0.05 to 0.25 percent of antioxidant.

The antioxidant can adopt ginseng root, Tea Polyphenol (TP), tocopherol, Butylated Hydroxyanisole (BHA) and the like, and by adopting the technical scheme, the antioxidant is favorable for helping the skin to reduce the generation of free radicals or accelerate the removal of the free radicals by adding the antioxidant, so that the antioxidant effect is better, and the anti-aging capacity of the skin is further improved.

In a second aspect, the present application provides a method for preparing a foundation solution, which adopts the following technical scheme:

a preparation method of foundation liquid comprises the following steps:

step 1), pretreating raw materials;

step 1-1), heating the solvent to 82-88 ℃, and preserving heat for 8-12 minutes at the temperature of 82-88 ℃ to obtain a first treated substance;

step 1-2), mixing and heating the emulsifier and the colorant to 82-88 ℃, stirring until the emulsifier and the colorant are completely dissolved, and then preserving heat for 8-12 minutes at the temperature of 82-88 ℃ to obtain a second pretreatment substance;

step 2), mixing the first treated substance and the second pretreated substance, uniformly stirring, and preserving heat at 82-88 ℃ for 28-32 minutes to obtain a second treated substance;

step 3), cooling the second processed product to 43-47 ℃, adding the angelica sinensis extract, the ganoderma lucidum stem extract and the astragalus membranaceus extract, and uniformly stirring to obtain a foundation solution;

the step 1-1 and the step 1-2 can be carried out simultaneously or sequentially.

By adopting the technical scheme, the emulsifier and the colorant are mixed and heated to 82-88 ℃, stirred to be completely dissolved, and then kept at the temperature of 82-88 ℃ for 8-12 minutes, so that the colorant is dispersed more uniformly, and the emulsifier is favorable for exerting better emulsification.

By uniformly mixing the first pretreatment substance and the second pretreatment substance together, the first pretreatment substance is heated and is kept at the temperature of 82-88 ℃ for 28-32 minutes, so that the emulsification effect of the second pretreatment substance in the first treatment substance is better, and the substances in the second mixture are uniformly distributed. The second treated substance is cooled to 43-47 ℃, and then the angelica sinensis extract, the ganoderma lucidum stem extract and the astragalus membranaceus extract are added and stirred uniformly, so that the active ingredients in the plant extracts keep better activity, and the added plant extracts can exert respective effects as better as possible.

Preferably, in the step 1-1), glycerol and propylene glycol are added into a solvent together, heated to 82-88 ℃, and stirred until all the components are completely dissolved;

in the step 1-2), mixing cetyl PEG/PPG-10/1 polydimethylsiloxane, polyglycerol-3 diisostearate, magnesium stearate, polydimethylsiloxane, aluminum hydroxide, cyclomethicone, isononyl isononanoate and octyl methicone with a colorant, heating to 82-88 ℃, and stirring until all the components are completely dissolved;

in the step 3), adding the antioxidant, the licorice extract, the centella asiatica extract, the scutellaria baicalensis extract, the atractylodes macrocephala extract, the saposhnikovia divaricata extract, the ganoderma lucidum stem extract, the astragalus membranaceus extract and the angelica sinensis extract into the second treatment substance, and uniformly stirring.

By adopting the technical scheme, in the step 1-1), the glycerol and the propylene glycol are added into the solvent together, so that the components are well dispersed in the solvent in the heating process.

The problems of low-temperature precipitation of the silicone oil can be solved due to the fact that the isononyl isononanoate is good in compatibility with the silicone oil, and meanwhile, the silicone oil has good dispersing capacity for a colorant, so that the components are dispersed more uniformly after being mixed, and a stable state is kept.

In summary, the present application includes at least one of the following beneficial technical effects:

1. by adding the angelica sinensis extract, the ganoderma lucidum stem extract and the astragalus membranaceus extract, the formula has multiple anti-aging effects, the angelica sinensis extract further improves the ability of resisting antagonistic free radicals of skin tissues, the effects of preventing wrinkles and moistening the skin of the astragalus membranaceus extract are obviously enhanced, and the multiple anti-aging ability of the foundation liquid is higher;

2. by adding the humectant, the skin moisturizing effect is better, and meanwhile, the air permeability is better, so that the skin can be kept in a moisturizing state for a longer time, and the skin can be kept in a healthy state;

3. by adding the emollient, the dispersing effect on the colorant is better, the foundation liquid can be more uniformly coated, the lipid content of the upper layer of the skin is improved, excessive degreasing and drying of the skin are prevented, and the skin is kept soft, smooth and elastic.

Detailed Description

The information on the source of each raw material component in the following examples and comparative examples is shown in Table 1

TABLE 1

Examples 1 to 3: a liquid foundation comprising the following components:

radix Angelicae sinensis extract, Ganoderma stem extract, radix astragali extract, emulsifier, colorant, and solvent. The emulsifier is the compound of cetyl PEG/PPG-10/1 polydimethylsiloxane and polyglycerol-3 diisostearate; the colorant is a compound of titanium dioxide, iron oxide red, iron oxide yellow and iron oxide black; the solvent is water. EXAMPLES 1-5, the amounts (in Kg) of the ingredients added are specified in Table 2

TABLE 2

Examples 1-5 the method of preparing the liquid foundation includes the steps of:

step 1), pretreating raw materials;

step 1-1), adding water into a first stirring kettle at a rotating speed of 60r/min, then heating to 85 ℃ while stirring, and firstly preserving heat at the temperature of 85 ℃ for 10 minutes to obtain a first treated substance;

step 1-2), selecting cetyl PEG/PPG-10/1 polydimethylsiloxane, polyglycerol-3 diisostearate, titanium dioxide, iron oxide red, iron oxide yellow and iron oxide black according to the formula of each embodiment, putting the materials into a second stirring kettle at the rotating speed of 120r/min, heating the materials to 85 ℃ while stirring, then preserving the heat at the temperature of 85 ℃ for 10 minutes, and discharging the materials into a container to obtain a second pretreatment substance;

step 2), putting the second pretreatment substance into the first treatment substance, stirring at the rotating speed of 60r/min for 3min, uniformly stirring, and preserving heat at the temperature of 85 ℃ for 30min to obtain a second treatment substance;

step 3), cooling the second treated substance to 45 ℃, adding the angelica sinensis extract, the ganoderma lucidum stem extract and the astragalus membranaceus extract into the second treated substance, stirring for 3min at the rotation speed of 60r/min, and uniformly stirring to obtain a foundation solution;

wherein the step 1-1) and the step 1-2) can be carried out simultaneously or sequentially.

Example 6

Compared with example 2, the difference is only that: in step 1-1), water was heated to 88 ℃.

In the step 1-2), the mixture is heated to 88 ℃ while stirring, and then is kept at 85 ℃ for 12 minutes. In step 2), the incubation was carried out at 88 ℃ for 32 minutes. In step 3), the second treated material was cooled to 47 ℃.

Example 7

Compared with example 2, the difference is only that: in step 1-1), water was heated to 82 ℃. In the step 1-2), the mixture is heated to 82 ℃ while stirring, and then the temperature is kept at 82 ℃ for 8 minutes. In step 2), the incubation was carried out at 82 ℃ for 28 minutes. In step 3), the second treated material was cooled to 43 ℃.

Examples 8 to 10

Compared with example 2, the difference is only that: the components of the foundation fluid also comprise: compounding of licorice extract, centella extract, scutellaria extract, atractylodes extract, ledebouriella root extract and magnesium stearate. The amounts (in Kg) charged in examples 8 to 10 minutes are specified in Table 3

TABLE 3

Putting the magnesium stearate, cetyl PEG/PPG-10/1 polydimethylsiloxane, polyglycerol-3 diisostearate, titanium dioxide, iron oxide red, iron oxide yellow and iron oxide black into a second stirring kettle in the step 1-2), and uniformly stirring. Adding Glycyrrhrizae radix extract, herba Centellae extract, Scutellariae radix extract, Atractylodis rhizoma extract, and radix Saposhnikoviae extract in step 3) together with radix Angelicae sinensis extract, Ganoderma stem extract, and radix astragali extract into the second treated material, and stirring.

Examples 11 to 13

Compared with example 2, the difference is only that: the foundation liquid also comprises a humectant. The humectant is a compound of polydimethylsiloxane, glycerol and propylene glycol. In examples 9 to 11, the amounts (in Kg) of the respective components added are specified in Table 4

TABLE 4

Adding the glycerol and the propylene glycol into the first stirring kettle together with the water in the step 1-1), and uniformly stirring.

The polydimethylsiloxane, the cetyl PEG/PPG-10/1 polydimethylsiloxane, the polyglycerol-3 diisostearate, the titanium dioxide, the iron oxide red, the iron oxide yellow and the iron oxide black are put into a second stirring kettle in the step 1-2) and are uniformly stirred.

Examples 14 to 16

Compared with example 2, the difference is only that: the foundation liquid also comprises an emollient. The emollient is a compound of aluminum hydroxide, cyclomethicone, isononyl isononanoate and octyl methicone. In examples 14 to 16, the amounts (in Kg) of the respective components added are specified in Table 5

TABLE 5

Examples 17 to 19

Compared with example 2, the difference is only that: the foundation liquid also comprises an antioxidant. The antioxidant is Ginseng radix. In examples 17-19, the amounts (in Kg) of each component added are specified in Table 6

TABLE 6

The ginseng root is added to the second processed material together with the angelica sinensis extract, the ganoderma lucidum stem extract and the astragalus membranaceus extract in the step 3), and the mixture is stirred uniformly.

Examples 20 to 22

Compared with example 2, the difference is only that: the foundation liquid also comprises a thickening agent and a filling agent. The thickener is a compound of triethoxy octyl silane and quaternary ammonium salt-18 bentonite; the filler is the compound of mica and magnesium sulfate. In examples 20 to 22, the amounts (in Kg) of the respective components added are specified in Table 7

TABLE 7

Adding magnesium sulfate and water into the first stirring kettle in the step 1-1), and uniformly stirring.

Triethoxyoctylsilane, quaternary ammonium salt-18 bentonite and mica are put into a second stirring kettle together with cetyl PEG/PPG-10/1 polydimethylsiloxane, polyglycerol-3 diisostearate, titanium dioxide, iron oxide red, iron oxide yellow and iron oxide black in the step 1-2) and are stirred uniformly.

Examples 23 to 25

Compared with example 2, the difference is only that: the foundation liquid also comprises antiseptic and aromatic. The preservative is a compound of phenoxyethanol, methyl hydroxybenzoate and propyl hydroxybenzoate; the aromatic is essence. In examples 23 to 25, the amounts (in Kg) of the respective components added are specified in Table 8

TABLE 8

The methyl hydroxybenzoate and the propyl hydroxybenzoate, cetyl PEG/PPG-10/1 polydimethylsiloxane, polyglycerol-3 diisostearate, titanium dioxide, iron oxide red, iron oxide yellow and iron oxide black are put into a second stirring kettle in the step 1-2) and are uniformly stirred. Adding phenoxyethanol and essence in step 3) together with radix Angelicae sinensis extract, Ganoderma lucidum stem extract and radix astragali Mongolici extract when the temperature is reduced to 40 deg.C, rotating at 60r/min, stirring for 3min, and mixing well.

Examples 26 to 28

Compared with example 2, the difference is only that: the components of the foundation fluid also comprise: licorice extract, centella asiatica extract, scutellaria baicalensis extract, atractylodes macrocephala extract, saposhnikovia divaricata extract, magnesium stearate, humectant, emollient, antioxidant, thickener, filler, preservative, fragrance. The humectant is a compound of polydimethylsiloxane, glycerol and propylene glycol; the emollient is the compound of aluminum hydroxide, cyclomethicone, isononyl isononanoate and octyl methicone; the antioxidant is Ginseng radix; the thickener is a compound of triethoxy octyl silane and quaternary ammonium salt-18 bentonite; the filler is the compound of mica and magnesium sulfate; the preservative is a compound of phenoxyethanol, methyl hydroxybenzoate and propyl hydroxybenzoate; the aromatic is essence. In examples 26 to 28, the amounts (in Kg) of the respective components charged are shown in Table 9

TABLE 9

Adding glycerol, propylene glycol and magnesium sulfate in the step 1-1) and water into a first stirring kettle, and uniformly stirring. Adding magnesium stearate, polydimethylsiloxane, aluminum hydroxide, cyclomethicone, isononyl isononanoate, octyl methicone, triethoxyoctyl silane, quaternary ammonium salt-18 bentonite, mica, methyl hydroxybenzoate and propyl hydroxybenzoate in the step 1-2) together with cetyl PEG/PPG-10/1 polydimethylsiloxane, polyglycerol-3 diisostearate, titanium dioxide, red iron oxide, yellow iron oxide and black iron oxide into a second stirring kettle, and uniformly mixing. Adding Glycyrrhrizae radix extract, herba Centellae extract, Scutellariae radix extract, Atractylodis rhizoma extract, radix Saposhnikoviae extract, and antioxidant in step 3) together with radix Angelicae sinensis extract, Ganoderma stem extract, and radix astragali extract into the second treated material, and stirring. Adding phenoxyethanol and essence in step 3) at 40 deg.C, adding radix Angelicae sinensis extract, Ganoderma lucidum stem extract and radix astragali extract, stirring at 60r/min for 3min, and stirring.

Comparative example 1

Compared with example 2, the difference is only that: in the step 3), the equivalent amount of water is adopted to replace the angelica sinensis extract, the ganoderma lucidum stem extract and the astragalus membranaceus extract.

Comparative example 2

Compared with example 2, the difference is only that:

in the step 3), the ganoderma lucidum stem extract and the astragalus membranaceus extract are replaced by the same amount of water.

Comparative example 3

Compared with example 2, the difference is only that:

in the step 3), the angelica sinensis extract and the astragalus membranaceus extract are replaced by the same amount of water.

Comparative example 4

Compared with example 2, the difference is only that:

in the step 3), the equivalent amount of water is adopted to replace the angelica sinensis extract and the ganoderma lucidum stem extract.

Comparative example 5

Compared with example 2, the difference is only that:

in the step 3), the angelica sinensis extract is replaced by the same amount of water.

Comparative example 6

Compared with example 2, the difference is only that:

in the step 3), the ganoderma lucidum stem extract is replaced by the same amount of water.

Comparative example 7

Compared with example 2, the difference is only that:

in step 3), the extract of Astragalus membranaceus is replaced with equal amount of water.

Experiment 1

The foundation solutions prepared in the examples and comparative examples were tested for safety according to the method of technical specifications for cosmetic safety (2015 edition), and the safety tests included detection of microorganisms and detection of physical and chemical properties. The microbiological assay data are detailed in table 10:

watch 10

	Mould and yeast CFU/g	Heat-resistant Escherichia coli	Staphylococcus aureus	Pseudomonas aeruginosa
					Technical requirements	≤100	Cannot be detected	Cannot be detected	Cannot be detected
Example 2	＜10	Not detected out	Not detected out	Not detected out
					Example 18	＜10	Not detected out	Not detected out	Not detected out
Example 27	＜10	Not detected out	Not detected out	Not detected out
					Comparative example 1	＜10	Not detected out	Not detected out	Not detected out
Comparative example 2	＜10	Not detected out	Not detected out	Not detected out
					Comparative example 6	＜10	Not detected out	Not detected out	Not detected out

The physical and chemical detection data are shown in Table 11:

TABLE 11

According to the detection data in tables 10 and 11, the safety performance detection of the foundation liquid prepared in the examples and comparative examples meets the standard requirements, and the foundation liquid prepared in the examples and comparative examples has high safety and is not easy to harm human bodies.

Experiment 2

Free radical (DPPH) clearance experiments: taking 3mL of DPPH-anhydrous methanol solution with the concentration of 0.0178mmol/L, adding 3mL of solution to be detected prepared from the foundation solution prepared in each example and comparative example, mixing, immediately measuring the light absorption value at the wavelength of 517nm, marking as A1, storing at 37 ℃ in the dark for 30min, marking as A2, and calculating the DPPH free radical clearance according to the following formula, wherein the light absorption value of the blank control group is a solution only added with DPPH-anhydrous methanol solution, and the light absorption value of the blank control group is marked as A3: DPPH free radical clearance (%) [1- (a1-a2)/A3] × 100%, and an average of three measurements was taken.

Experiment 3

According to T/SHRH 023-2019 in-vitro recombination 3D epidermis model test method for testing barrier efficacy of cosmetics, half effective time ET of foundation solution prepared in each embodiment and comparative example is detected₅₀。

Experiment 4

Superoxide anion radical scavenging experiment: taking 2.8mL of 50mmol/L Tris (hydroxymethyl) aminomethane hydrochloride buffer solution (Tris-HCL) (with the pH value of 8.2) buffer solution, adding 0.1mL of foundation solution prepared in each example and comparative example, putting the foundation solution into a water bath kettle at 25 ℃ for 10min, adding 0.1mL of pyrogallol at 25 ℃ with the concentration of 6mmol/L, fully mixing, accurately reacting for 3min, beginning timing when the pyrogallol is added, and adding 5mL of 5% ascorbic thrombus to stop the reaction. After 10min, measuring absorbance at 420nm, zeroing with equal volume of 10mmol/LHCL instead of pyrogallol solution, replacing sample with equal volume of distilled water, and recording absorbance value as A₀. Superoxide anion radical clearance was calculated according to the following formula: superoxide anion radical clearance rate [ [ (A)₀-A)/A₀]100%, taking the average of three measurements, wherein A₀For the absorbance of the control, A is the absorbance of the foundation solution prepared in each example and comparative example.

Experiment 5

XTT is a tetrazole nitrogen derivative, can be degraded and reduced into water-soluble brown yellow formazan products by mitochondrial dehydrogenase in living cells, and the generation amount of the formazan is positively correlated with the activity of cell mitochondria, so that the XTT method can be used for detecting the activity of the mitochondria so as to react the metabolic capability of the cells.

Inoculating human immortalized keratinocyte (HaCaT) cells into a limiting keratinocyte serum-free medium (DK-SFM), placing the cells in a constant-temperature incubator at the temperature of 37 ℃ and the volume fraction of CO2 of 5 percent for 5 days until the cells are fused, and changing the culture solution every other day. In the experiment, the cell culture bottle is taken out, HaCaT cells are digested for 4min by trypsin, then the cells are inoculated and incubated with a 96-well plate for 24h, and 200 mu L of DK-SFM culture medium is added into each wellThe resulting liquid foundations of examples and comparative examples, which had a solid content of 0.1mg/mL and were diluted with nutrient solution, were measured after 48 hours in an incubator. Adding medicine for incubation, dissolving XTT into 0.2mg/mL solution by preheating at 60 deg.C, removing cell culture solution from 96-well plate, adding XTT/PMS (200:1) (PMS refers to phenazine methyl sulfate) into each well, culturing at 37 deg.C for 2 hr, measuring absorbance OD at 450nm wavelength on microplate reader, and determining absorbance 0D according to that measured in comparative example 1₀As a reference value, the ratio of mitochondrial activity to OD/0D was obtained by dividing the absorbance of each example or each comparative example by the absorbance of comparative example 1 and multiplying by 100%₀The absorbance 0D of comparative example 1 was subtracted from the absorbance OD of each example or each comparative example by calculation₀The boosted value is obtained, and the boosted value is divided by the light absorption value 0D of each example or each comparative example and multiplied by 100%, so that the boosting ratio is obtained. The assay data for experiments 2-5 are detailed in Table 12:

TABLE 12

As can be seen from comparison of the data of comparative example 2 and comparative example 1 in table 12, the angelicae gigantis radix extract has a high radical scavenging rate and a good antioxidant effect, so that skin aging is delayed, the angelicae gigantis radix extract can promote stem cell proliferation, the effective time of the angelicae gigantis radix extract is increased after the angelicae gigantis radix extract is added, so that the effect of strengthening the skin barrier is good, and the angelicae gigantis radix extract has the effect of improving the anti-aging capacity of the skin.

As can be seen from comparison of the data of comparative example 3 and comparative example 1 in table 12, the free radical scavenging rate was improved after addition of the ganoderma lucidum stem extract, demonstrating that the antioxidant ability was enhanced, and the mitochondrial activity ratio was improved, demonstrating that the ganoderma lucidum stem extract has the effect of promoting metabolism.

As can be seen from comparison of the data of comparative example 4 and comparative example 1 in table 13, the addition of the astragalus membranaceus extract increased the radical scavenging rate, demonstrating that the antioxidant capacity was enhanced, and the proliferation of cortical cells was stimulated, so that the increase ratio was increased, and the metabolism of skin tissues was promoted, thereby improving the anti-aging effect.

As can be seen from comparison of the data in table 12 in comparative example 5 and comparative example 4, when the extract of stem of ganoderma lucidum was used in combination with the extract of astragalus membranaceus, the radical scavenging rate and the mitochondrial activity ratio of the extract of astragalus membranaceus were both slightly improved and were not greatly changed, which proves that the extract of stem of ganoderma lucidum had no significant negative effect on the extract of astragalus membranaceus.

As can be seen from comparison of the data in table 12 in comparative example 7 and comparative example 2, when the angelicae gigantis radix extract and the ganoderma lucidum stem extract were used in combination, the half effective time and the radical scavenging rate of the angelicae gigantis radix extract were less significantly changed, which indicates that the ganoderma lucidum stem extract has no significant negative effect on the angelicae gigantis radix extract.

As can be seen from comparison of the data in table 12 in comparative example 6 with comparative examples 2 and 4, when the dongguang extract and the podded astragalus extract were used in combination, the radical scavenging rate and the mitochondrial activity ratio of the podded astragalus extract were both reduced to some extent, which proves that the dongguang extract has an inhibitory effect on the antioxidant ability and the metabolism promotion, and half of the effective time is reduced, indicating that the podded astragalus extract has a certain inhibitory effect on the dongguang extract, thereby deteriorating the anti-aging ability to some extent.

According to the comparison of the data of example 2 and comparative example 6 in table 12, the free radical scavenging rate is greatly increased by adding the ganoderma lucidum stem extract, which indicates that the antioxidant capacity is high, thereby further improving the living environment of skin cells, the half effective time and the mitochondrial activity are greatly increased, which indicates that the ganoderma lucidum stem extract relieves the inhibition effect of the angelica sinensis extract on the astragalus membranaceus extract, and improves the effects of preventing wrinkles and moisturizing skin, thereby proving that the capacity of strengthening the skin barrier is remarkably high, and further the anti-aging effect is good in all aspects.

According to comparison of the data of examples 8-10 and example 2 in table 12, the addition of the licorice extract, the centella asiatica extract, the scutellaria baicalensis extract, the atractylodes macrocephala extract, the saposhnikovia divaricata extract and the magnesium stearate improves half of the effective time, promotes metabolism to a certain extent, proves that the damaged parts of the skin can be further lubricated, and the skin can be helped to absorb energy of corresponding substances better, so that healing and repairing of the skin are accelerated, the elasticity of the skin is effectively improved, the skin barrier is more stable, and the repairing, nursing and anti-aging effects of the foundation liquid are better.

As can be seen from comparison of the data in examples 11 to 13 and example 2 in table 12, the moisture in the skin can be retained by adding the humectant, so that the mitochondrial activity is improved to a certain extent, which proves that the effect of promoting metabolism is better, the absorption promoting effect is provided for the skin, and the anti-aging effect of the foundation fluid is better.

According to the comparison of the data of examples 14-16 and example 2 in table 12, the skin can be better moisturized by adding the emollient, so that the half effective time is increased to a certain extent, and the skin is proved to have enhanced capability of resisting the invasion of the irritant, thereby being beneficial to maintaining the stability of the barrier of the skin and effectively protecting the skin.

As can be seen from comparison of the data in examples 20-25 and example 2 in Table 12, the radical scavenging rate was improved by the addition of the thickener, filler, and preservative, indicating that the mixing of the components can maintain good stability, thus demonstrating that the foundation solution has a stable antioxidant effect and improved anti-aging ability.

According to comparison of the data of examples 26 to 28 in table 12 with the data of example 2, the radical scavenging rate is improved to a certain extent by adding the licorice extract, the centella asiatica extract, the scutellaria baicalensis extract, the atractylodes macrocephala extract, the saposhnikovia divaricata extract, the magnesium stearate, the moisturizer, the emollient, the antioxidant, the thickener, the filler, the preservative and the fragrance, so that the components can better exert respective effects, the antioxidant capacity of the skin is further improved by matching the components, the half effective time is slightly prolonged, the absorption of the skin is promoted, the self-repairing capacity of the skin is further improved, and the multiple anti-aging effects of the foundation fluid are further enhanced.

The above embodiments are preferred embodiments of the present application, and the protection scope of the present application is not limited by the above embodiments, so: all equivalent changes made according to the structure, shape and principle of the present application shall be covered by the protection scope of the present application.

Claims

1. A foundation liquid is characterized in that: the paint comprises the following components in parts by mass:

0.05 to 0.21 percent of angelica sinensis extract;

0.06% -0.22% of ganoderma lucidum stem extract;

0.25 to 0.45 percent of astragalus membranaceus extract;

2.5 to 5.5 percent of emulsifier;

5.95 to 10.65 percent of colorant;

the balance of solvent;

the total mass percentage is 100 percent.

2. The liquid foundation of claim 1, wherein: the paint also comprises the following components in percentage by mass:

0.4 to 0.9 percent of liquorice extract;

centella asiatica extract 0.3% -0.8%;

0.15 to 0.55 percent of radix scutellariae extract;

0.2 to 0.5 percent of white atractylodes rhizome extract;

0.2 to 0.6 percent of divaricate saposhnikovia root extract;

0.15 to 0.75 percent of magnesium stearate.

3. The liquid foundation of claim 1, wherein: the emulsifier is one or more of cetyl PEG/PPG-10/1 polydimethylsiloxane, polyglycerol-3 diisostearate, hydrogenated lecithin and glycerol stearate citrate.

4. The liquid foundation of claim 1, wherein: the paint also comprises the following components in percentage by mass:

22% -27.5% of humectant;

the humectant is one or a compound of a plurality of polydimethylsiloxane, glycerol and propylene glycol.

5. The liquid foundation of claim 4, wherein: the humectant comprises the following components in percentage by mass:

9% -10.5% of polydimethylsiloxane;

7.5% -10% of glycerol;

5.5 to 7 percent of propylene glycol.

6. The liquid foundation of claim 1, wherein: the paint also comprises the following components in percentage by mass:

20% -27% of an emollient;

the emollient is one or more of aluminum hydroxide, cyclomethicone, isononyl isononanoate and octyl methicone.

7. The liquid foundation of claim 6, wherein: the emollient comprises the following components in percentage by mass:

3.5 to 5 percent of aluminum hydroxide;

9% -10.5% of cyclopolydimethylsiloxane;

isononyl isononanoate 6% -8.5%;

1.5 to 3 percent of octyl polymethylsiloxane.

8. The liquid foundation of claim 1, wherein: the paint also comprises the following components in percentage by mass:

0.05 to 0.25 percent of antioxidant.

9. A method for preparing the foundation liquid according to claim 1, characterized in that: the method comprises the following steps:

step 1), pretreating raw materials;

the step 1-1) and the step 1-2) can be carried out simultaneously or sequentially.

10. The method for preparing a liquid foundation according to claim 9, characterized in that: in the step 1-1), glycerol and propylene glycol are added into a solvent together, heated to 82-88 ℃, and stirred until all components are completely dissolved;