CN107898660A - A kind of tender skin water light stoste and its preparation method and application - Google Patents

A kind of tender skin water light stoste and its preparation method and application Download PDF

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Publication number
CN107898660A
CN107898660A CN201710940913.5A CN201710940913A CN107898660A CN 107898660 A CN107898660 A CN 107898660A CN 201710940913 A CN201710940913 A CN 201710940913A CN 107898660 A CN107898660 A CN 107898660A
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Prior art keywords
water light
tender skin
skin water
skin
parts
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杨菊
曹波
黄振振
刘运花
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Guangdong Bailichen Biotechnology Co., Ltd.
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Guangzhou Bailichen Cosmetics Co Ltd
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Priority to CN201710940913.5A priority Critical patent/CN107898660A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
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    • A61K8/67Vitamins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract

The invention discloses a kind of tender skin water light stoste and its preparation method and application, described its compositing formula of tender skin water light stoste in terms of 100 parts of mass fraction, including:0.1~0.5 part of thickener, 20~23 parts of moisturizer, 0.1~0.2 part of hyaluronic acid, 0.3~1 part of biological 1,0.1~0.4 part of carbohydrate gum, 9,1~5 parts of Argireline beta glucan, 0.1~0.2 portion of preservative, 1~2 part of anti-sensitizer, surplus is water.Tender skin water light stoste of the present invention only just can permeate flesh bottom through smearing, realize quick moisturizing without injection; skin protective barrier is formed, lasting water lock moisturizing, effectively suppresses, desalinates the formation of all types of wrinkles such as wrinkles on one's forehead, crow's feet, decree line; relax one's muscles, potent increase elasticity of skin.Suitable for a variety of skin, the crease-resistant multiple efficacies of moisturizing and skin rejuvenating are realized.

Description

A kind of tender skin water light stoste and its preparation method and application
Technical field
The present invention relates to technical field of skin care, and in particular to a kind of tender skin water light stoste and its preparation method and application.
Background technology
Water and milk stoste existing for Cosmetic Market has clearly moist effect, but usually effect is more single, general Focus on moisturizing, moisturizing, portioned product can slightly have auxiliary effect of light speckles, beautification and white, and the skin-protecting function of essence cream class is more comprehensive available Change, but it is more glutinous greasy, and the scope of application is limited to weather and skin quality.Secondly, very popular water laser accunputure is again due to inconvenient, secondary The reason such as more, expensive is acted on to fail to meet most of consumer's needs.
For this vacancy, a kind of skin sense is salubrious and collection replenishing water and preserving moisture, crease-resistant print of dispelling, anti-aging etc. to develop by the present invention The non-injection type water light stoste or raw material of multiple efficacies, disclose a kind of micro- tender skin water light stostes of note of Ou Boer, utilize small molecule The strong permeability of Sodium Hyaluronate, can promote absorption of the skin to functional nutrient component, and the anti-sensitizer and preservative of addition are equal It is combined for plant extracts, without allergic reaction after any skin quality use.
The content of the invention
The technical problem to be solved in the present invention is for the single technical deficiency of existing moisturizing product function, there is provided Yi Zhongjian The smearing that the complex function such as crease-resistant is repaired in tool moisturizing declines the tender skin water light stoste of note, utilizes the strong of similar " microinjection " concept of product Permeability, available for the quick replenishing water and preserving moisture of skin, and intelligently adjusts sebum secretion, promotes skin cell metabolism renewal, releives and dispel Print, is wrinkle resistant anti-ageing.
Another technical problem to be solved by the present invention is that provide the preparation method of the tender skin water light stoste.
A present invention also technical problems to be solved are to provide the application of the tender skin water light stoste.
The purpose of the present invention is achieved through the following technical solutions:
A kind of tender skin water light stoste is provided, its compositing formula in terms of 100 parts of mass fraction, including:0.1~0.5 part of thickening Agent, 20~23 parts of moisturizer, 0.1~0.2 part of hyaluronic acid, 0.3~1 part of biological carbohydrate gum -1,0.1~0.4 part of Argireline -9,1 ~5 parts of beta glucans, 0.1~0.2 portion of preservative, 1~2 part of anti-sensitizer, surplus is water.
The water that the water allows to use for skin care item or Cosmetic Manufacture, including sterile water or deionized water or purified water Deng.
Preferably, the thickener is Carbopol 941 and Acritamer 940.
It is further preferred that the Carbopol 941 and Acritamer 940 are (1.5~3) according to mass ratio:1 mixing.
Preferably, the moisturizer is the mixing being obtained by mixing by polyalcohol, fucose, glycine betaine and ethoxy urea Thing, wherein the polyalcohol is one or more combinations in 1,2-PD, 1,3-BDO or glycerine.
It is further preferred that the polyalcohol, fucose, glycine betaine, ethoxy urea mixed proportion are by mass:(6~ 12):(1~3):(1~4):(1~5).
Preferably, the Sodium Hyaluronate is the Sodium Hyaluronate of two kinds of molecular weight, is 1,300,000 dalton hyalomitomes respectively Sour sodium and 500,000 Dalton molecular weight Sodium Hyaluronates.The present invention is transparent using 1,300,000 macromolecules and 500,000 small-molecular-weights Matter acid sodium collective effect, realizes moisturizing and the lasting moisturizing effect of water lock.It is further preferred that two kinds of molecular weight of Sodium Hyaluronate Proportion of composing, in terms of mass ratio, 1,300,000 molecular weight Sodium Hyaluronates:500000 molecular weight Sodium Hyaluronates are (1.5~3):1 Under this ratio, play and act synergistically with other components, obtain moisturizing and persistently moisten optimum efficiency with water lock.
Preferably, the anti-sensitizer mixes for graceful quick, dipotassium glycyrrhizinate difficult to understand or using antiallergic antipruritic and Austria Graceful quick, dipotassium glycyrrhizinate mixes.
The antiallergic antipruritic main component is hanfangchin A or tetrandrine or tetrandrine, be by trehalose, Ophiopogon root, turn round the vegetalitas antiallergic active ingredient that the extracts such as thorn cactus, radix sophorae mix.
The dipotassium glycyrrhizinate preferably use with radix glycyrrhizae extract obtained by product.It is described it is difficult to understand it is graceful it is quick by Bacillus acidi lactici, The filtering extraction of soya-bean milk tunning.
Further preferably the anti-sensitizer is antiallergic antipruritic and graceful quick, dipotassium glycyrrhizinate difficult to understand with 10:5:1 ratio is mixed Conjunction forms.
Preferably, the preservative is resistance to true plant antiseptic agent, is purchased from Beijing Nai Que biochemical technologies research institute, main component It is composed for Chinese prickly ash berry extract with Fructus Citri grandis extract.
Present invention simultaneously provides the preparation method of the tender skin water light stoste, comprise the following steps:
S1. with sterile water dissolving moisturizer, Sodium Hyaluronate and thickener, dissolve by heating and keep the temperature homogeneous;
S2. the pH value of system obtained by regulating step S1 is 5.5~6.5;
S3. system obtained by step S2 is cooled to less than 45 DEG C;
S4. biological carbohydrate gum -1, Argireline -9, beta glucan, preservative, anti-sensitizer are added into system obtained by step S3, Mix slowly uniformly up to the tender skin water light stoste;
Heating described in preferred steps S1 is heated to 70~95 DEG C, and the time of homogeneous is 1~5min, and the time of insulation is 10 ~30min;
PH value agents useful for same is adjusted described in preferred steps S2 as triethanolamine, sodium hydroxide, potassium hydroxide, citric acid, lemon The one or more of lemon acid sodium, tartaric acid, sodium tartrate, phytic acid or acetic acid etc..
Present invention simultaneously provides the application of the tender skin water light stoste, and it is crease-resistant can be advantageously applied to moisturizing as raw material Class cosmetics, additive amount can be the 10%~40% of the cosmetic material gross mass.The present invention is alternatively arranged as skin matrix, addition Functional component, is made multiple-effect skin care item, and the functional component of addition can be amino acid, vitamin, have the function of energy active ingredient Plant extracts, epidermal growth factor etc..
The invention has the advantages that:
The present invention can realize quick benefit with the sub- rank Sodium Hyaluronate compatible use of two amounts, the hyaluronic acid of small molecule The compound several functions moisturizing ingredient of water, the hyaluronic acid of macromolecular, can form skin protective barrier, lasting water lock moisturizing, energy Quick moisturizing, continues water profit moisturizing, and bright color, makes skin light sensation brilliant white, and realizes that jade-like stone profit is fine and smooth as " water light ";Without note Penetrate, only just can permeate flesh bottom through smearing, realize the ideal effect of " microinjection " concept.On this basis, the biology of rational proportion Carbohydrate gum -1 and potent polypeptide protein Argireline -9 act synergistically, and fill the concave skin tissue of aging, can effectively suppress wrinkles on one's forehead, The formation of all types of wrinkles such as facial river line, crow's feet, desalinates acne print, eliminates microgroove, relaxs one's muscles, potent increase elasticity of skin With gloss.In addition, contained compound antianaphylaxis components can eliminate various allergy hidden danger in stoste formula, realize that replenishing water and preserving moisture is crease-resistant Multiple efficacies.Verify after tested, the present invention is safe and reliable, moisturizing can be used as to repair class shin moisturizer long-time service, be named as Ou Bo You are micro- to note tender skin water light stoste.
The present invention is effectively formed by main of natural component, has good extension pardon, can be used as raw material very It is applied to the crease-resistant class cosmetics of moisturizing well, additive amount can be the 10%~40% of the cosmetic material gross mass.The present invention is also Skin matrix can be used as, adds functional component, multiple-effect skin care item are made, the functional component of addition can be amino acid, vitamin, tool It is functional can the plant extracts of active ingredient, epidermal growth factor etc., have broad application prospects.
Embodiment
The present invention is further illustrated with reference to specific embodiment.Following embodiments are only for illustration, it is impossible to manage Solve as limitation of the present invention.Unless stated otherwise, the raw material used in following embodiments is that conventional purchased in market or commercial sources obtain The raw material obtained, unless stated otherwise, the method and apparatus used in following embodiments is method commonly used in the art and sets It is standby.
For convenience of description, heretofore described primary raw material, wherein the producer illustrated does not limit the present invention, this area The similar products of other producers production can also be used based on compatibility thought of the present invention:Biological carbohydrate gum -1, No. CAS:283602- 75-5, its structural formula are as follows:
Beta glucan, No. CAS:160872-27-5, its structural formula is as follows, and beta glucan is one kind by glucose monomer group The polymer homopolysaccharide of Viability structure, can improve immunity, repair skin trauma effect, and removes free radical, improves table Skin growth factor (EGF) and moisturizing factor content, reach moisturizing, crease-resistant, anti-aging function and synergistic effect.
Fucose, No. CAS:2438-80-4, its structural formula are as follows:
Glycine betaine, No. CAS:107-43-7, its structural formula are as follows:
Ethoxy urea, No. CAS:2078-71-9, its structural formula are as follows:
Triethanolamine, No. CAS:102-71-6, its structural formula are as follows:
Antiallergic antipruritic, is purchased from Beijing Orient Miao Sen bio tech ltd, and main component is hanfangchin A or the Chinese Menispermine or tetrandrine, are by trehalose, ophiopogon root, turn round the vegetalitas pierced the extracts such as cactus, radix sophorae and be combined Antiallergic active ingredient, can effectively suppress the release of histamine phosphate, alleviate, repair itch, redness and the pain symptom of allergy skin, And suppress the activity of hyaluronidase in skin histology.
Booth difficult to understand is quick (difficult to understand graceful quick), and graceful purchased from French celestial being, sources refer to website www.axialys- The upper disclosed information of innovations.com.It is used as anti-allergic agent component in the present invention, and main composition is lactic acid bar 300 a variety of active ingredients of bacterium and the filtrate of soya-bean milk tunning, inner protein, amino acid, polypeptide, phosphatide, brass etc..
In the present invention, play suppression with antiallergic antipruritic, dipotassium glycyrrhizinate compatible use, three using booth difficult to understand is quick and be harmful to Bacterium grows, reduces feeling of pain caused by extraneous infringement skin, antianaphylactic effect synergistic effect immediately, with other active components Compatibility is good, and other active components can be promoted to play a role, and reaches the multi-efficiencies such as moisturizing, reparation and whitening.
Dipotassium glycyrrhizinate, it is normal purchased in market, No. CAS:68797-35-3, its structural formula are as follows:
Hyaluronic acid, No. CAS is:9004-61-9, its molecular structure are as follows:
Sodium Hyaluronate is the high poly- polysaccharide of acidity extracted in cockscomb or umbilical cord, has excellent water suction moisture retention, It is the best material of the humidity-preserving type being had found in nature, enjoys the title of " preferable natural moisturizing factor ".Small molecule it is transparent It is full that matter acid sodium can help skin quickly to absorb water, so as to strengthen elasticity, smooth out wrinkles, the Sodium Hyaluronate of macromolecular can have film forming Property, skin care barrier can be formed, lasting water lock moisturizing, compact skin.In addition, Sodium Hyaluronate be also human skin composition into Point.The present invention realizes that moisturizing is held with water lock using the Sodium Hyaluronate collective effect of 1,300,000 macromolecules and 500,000 small-molecular-weights Long moisturizing effect.
Argireline -9, No. CAS:1228371-11-6, it is conventional purchased in market;
Acritamer 940, No. CAS:9007-20-9;Carbopol 941, No. CAS:9003-01-4, is conventional purchased in market.
Resistance to true plant antiseptic agent, is purchased from Beijing Nai Que biochemical technologies research institute, and main component is Chinese prickly ash berry extract and shaddock Berry extract is composed, and by various plants extract mixing protective system, reaches complementary broad-spectrum antimicrobial effect, plant therein Thing polyphenol, brass, organic acid etc. can be inhibited bacteria effectively, the growth of mould, saccharomycete etc., relative chemical preservative and polyalcohol Class preservative, it is non-toxic, nonirritant, and resistance to really plant antiseptic agent performance is stablized, it is safe and efficient.
Embodiment 1
Following raw material is weighed according to mass parts:0.12 part of Carbopol 941,0.08 part of Acritamer 940,0.12 part 1,300,000 The Sodium Hyaluronate of molecular weight, 0.08 part of 500,000 molecular weight Sodium Hyaluronate, 2 parts of glycerine, 6 parts of glycerine, 8 parts of 1,3- fourths two Alcohol, 3 portions of fucoses, 2 parts of glycine betaines, 2 parts of ethoxy ureas, -1,0.3 part of Argireline -9 of 1 part of biological polyoses glue, 1 part of β-glucose, 0.1 portion of preservative, 1.6 parts of anti-sensitizers, surplus are 74 parts of sterile waters.
The tender skin water light stoste is prepared according to following processing step:
S1. with sterile water dissolving moisturizer (1,2 propane diols, glycerine, fucose, glycine betaine, ethoxy urea), hyalomitome Sour sodium and thickener (Carbopol 941 and Acritamer 940), are heated to 70 DEG C of dissolvings, and homogeneous 5min is transferred to grainless Emulsify pot insulation 20min;
S2. the pH value of system obtained by citric acid, sodium citrate regulating step S1 is 5;
S3. system obtained by step S2 is cooled to less than 45 DEG C;
S4. biological carbohydrate gum -1, Argireline -9, beta glucan, preservative, anti-sensitizer are added into system obtained by step S3, Mix slowly uniformly up to the tender skin water light stoste.
Embodiment 2
Following raw material is weighed according to mass parts:0.2 part of Carbopol 941,0.1 part of Acritamer 940,0.15 part 130 very much The Sodium Hyaluronate of son amount, 0.05 part of 500,000 molecular weight Sodium Hyaluronate, 4 parts of glycerine, 4 parts of glycerine, 5 parts of 1,3 butylene glycols, 1 Portion fucose, 3 parts of glycine betaines, 3 parts of ethoxy ureas, -1,0.2 part of Argireline -9 of 0.3 part of biological polyoses glue, 5 parts of β-glucose, 0.15 portion of preservative, 1 part of anti-sensitizer, surplus are 73.65 parts of sterile waters.
The tender skin water light stoste is prepared according to following processing step:
S1. with sterile water dissolving moisturizer (1,2 propane diols, glycerine, fucose, glycine betaine, ethoxy urea), hyalomitome Sour sodium and thickener (Carbopol 941 and Acritamer 940), are heated to 80 DEG C of dissolvings, and homogeneous 4min is transferred to grainless Emulsify pot insulation 30min;
S2. the pH value of system obtained by sodium hydroxide, acetic acid regulating step S1 is 5.5;
S3. system obtained by step S2 is cooled to less than 45 DEG C;
S4. biological carbohydrate gum -1, Argireline -9, beta glucan, preservative, anti-sensitizer are added into system obtained by step S3, Mix slowly uniformly up to the tender skin water light stoste.
Embodiment 3
Following raw material is weighed according to mass parts:0.3 part of Carbopol 941,0.2 part of Acritamer 940,0.06 part 130 very much The Sodium Hyaluronate of son amount, 0.04 part of 500,000 molecular weight Sodium Hyaluronate, 3 parts of glycerine, 5 parts of glycerine, 7 parts of 1,3 butylene glycols, 2 Portion fucose, 1 part of glycine betaine, 3 parts of ethoxy ureas, -1,0.4 part of Argireline -9 of 0.8 part of biological polyoses glue, 3 parts of β-glucose, 0.2 portion of preservative, 1.28 parts of anti-sensitizers, surplus are 73.8 parts of sterile waters.
S1. with sterile water dissolving moisturizer (1,2 propane diols, glycerine, fucose, glycine betaine, ethoxy urea), hyalomitome Sour sodium and thickener (Carbopol 941 and Acritamer 940), are heated to 85 DEG C of dissolvings, and homogeneous 3min is transferred to grainless Emulsify pot insulation 15min;
S2. the pH value of system obtained by triethanolamine regulating step S1 is 6;
S3. system obtained by step S2 is cooled to less than 45 DEG C;
S4. biological carbohydrate gum -1, Argireline -9, beta glucan, preservative, anti-sensitizer are added into system obtained by step S3, Mix slowly uniformly up to the tender skin water light stoste.
Embodiment 4
Following raw material is weighed according to mass parts:0.11 part of Carbopol 941,0.04 part of Acritamer 940,0.075 part 1,300,000 The Sodium Hyaluronate of molecular weight, 0.025 part of 500,000 molecular weight Sodium Hyaluronate, 6 parts of glycerine, 6 parts of 1,3 butylene glycols, 3 parts of rocks Algae sugar, 2 parts of glycine betaines, 4 parts of ethoxy ureas, -1,0.1 part of Argireline -9 of 0.5 part of biological polyoses glue, 4 parts of β-glucose, 0.2 part Preservative, 2 parts of anti-sensitizers, surplus are 73.75 parts of sterile waters.
S1. with sterile water dissolving moisturizer (1,2 propane diols, glycerine, fucose, glycine betaine, ethoxy urea), hyalomitome Sour sodium and thickener (Carbopol 941 and Acritamer 940), are heated to 95 DEG C of dissolvings, and homogeneous 1min is transferred to grainless Emulsify pot insulation 10min;
S2. the pH value of system obtained by citric acid, sodium citrate regulating step S1 is 6.5;
S3. system obtained by step S2 is cooled to less than 45 DEG C;
S4. biological carbohydrate gum -1, Argireline -9, beta glucan, preservative, anti-sensitizer are added into system obtained by step S3, Mix slowly uniformly up to the tender skin water light stoste.
Embodiment 5
Following raw material is weighed according to mass parts:0.12 part of Carbopol 941,0.08 part of Acritamer 940,0.12 part 1,300,000 The Sodium Hyaluronate of molecular weight, 0.08 part of 500,000 molecular weight Sodium Hyaluronate, 2 parts of glycerine, 6 parts of glycerine, 8 parts of 1,3- fourths two Alcohol, 3 portions of fucoses, 2 parts of glycine betaines, 2 parts of ethoxy ureas, -1,1 part of β-glucose of 1 part of biological polyoses glue, 0.1 portion of preservative, 1.6 parts of anti-sensitizers, surplus are sterile water.
The tender skin water light stoste is prepared according to following processing step:
S1. with sterile water dissolving moisturizer (1,2 propane diols, glycerine, fucose, glycine betaine, ethoxy urea), hyalomitome Sour sodium and thickener (Carbopol 941 and Acritamer 940), are heated to 70 DEG C of dissolvings, and homogeneous 5min is transferred to grainless Emulsify pot insulation 20min;
S2. the pH value of system obtained by citric acid, sodium citrate regulating step S1 is 5;
S3. system obtained by step S2 is cooled to less than 45 DEG C;
S4. biological carbohydrate gum -1, beta glucan, preservative, anti-sensitizer are added into system obtained by step S3, is mixed slowly The even tender skin water light stoste to obtain the final product.
Embodiment 6
Following raw material is weighed according to mass parts:0.12 part of Carbopol 941,0.08 part of Acritamer 940,0.12 part 1,300,000 The Sodium Hyaluronate of molecular weight, 0.08 part of 500,000 molecular weight Sodium Hyaluronate, 2 parts of glycerine, 6 parts of glycerine, 8 parts of 1,3- fourths two Alcohol, 3 portions of fucoses, 2 parts of glycine betaines, 2 parts of ethoxy ureas, 0.3 part of Argireline -9,0.1 portion of preservative, 1.6 parts of anti-sensitizers, surpluses For sterile water.
The tender skin water light stoste is prepared according to following processing step:
S1. with sterile water dissolving moisturizer (1,2 propane diols, glycerine, fucose, glycine betaine, ethoxy urea), hyalomitome Sour sodium and thickener (Carbopol 941 and Acritamer 940), are heated to 70 DEG C of dissolvings, and homogeneous 5min is transferred to grainless Emulsify pot insulation 20min;
S2. the pH value of system obtained by citric acid, sodium citrate regulating step S1 is 5;
S3. system obtained by step S2 is cooled to less than 45 DEG C;
S4. Argireline -9, preservative, anti-sensitizer are added into system obtained by step S3, is mixed slowly uniformly up to described Tender skin water light stoste.
Embodiment 7
Following raw material is weighed according to mass parts:0.12 part of Carbopol 941,0.08 part of Acritamer 940,2 parts of glycerine, 6 parts Glycerine, 8 parts of 1,3 butylene glycols, 3 portions of fucoses, 2 parts of glycine betaines, 2 parts of ethoxy ureas, 1 part of -1,0.3 part six of biological polyoses glue It is 74 parts of sterile waters to win peptide -9,1 part of β-glucose, 0.1 portion of preservative, 1.6 parts of anti-sensitizers, surplus.
The tender skin water light stoste is prepared according to following processing step:
S1. with sterile water dissolving moisturizer (1,2 propane diols, glycerine, fucose, glycine betaine, ethoxy urea), thickener (Carbopol 941 and Acritamer 940), is heated to 70 DEG C of dissolvings, and homogeneous 5min is transferred to emulsification pot insulation to grainless 20min;
S2. the pH value of system obtained by citric acid, sodium citrate regulating step S1 is 5;
S3. system obtained by step S2 is cooled to less than 45 DEG C;
S4. biological carbohydrate gum -1, Argireline -9, beta glucan, preservative, anti-sensitizer are added into system obtained by step S3, Mix slowly uniformly up to the tender skin water light stoste.
100 voluntary triers of women, at 18~50 years old age, arbitrarily select, daily in the products obtained therefrom of embodiment 1 to 7 Sooner or later it is each to smear once, during which if the adverse reactions such as allergy then termination test occurs in 1 people, adverse reaction is not as a result found. To exclude the interference of the effect of other functional cosmetics and medicine, tested sample is during experiment without using other medicines or function Property cosmetics, after continuous use the present embodiment product 28d, subjects skin is tested.
The results show:Formula described in comparative example 5 to 7, because lacking partial function component, in replenishing water and preserving moisture, light line Aspect has been short of, and subject's transepidermal water windage is larger, and " water light " filling effect is substantially insufficient.And it is real to smear the present invention The tender skin water light stoste of example 1 to 4 is applied, subjects skin's skin sense exquisiteness silk is slided, and skin metabolism is significantly accelerated, aged skin Recover elasticity and gloss to a certain extent, crow's feet, facial river line and part acne print are gradually desalinated.Illustrate the tender skin water of the present invention The quick moisturizing of light stoste energy, continues water lock, and realizes jade-like stone profit brilliant white as " water light ", securely and reliably, the crease-resistant class of moisturizing can be used as to protect Skin liquid long-time service.

Claims (10)

1. a kind of tender skin water light stoste, it is characterised in that based on 100 parts of quality total amount, formula composition is for example following:0.1~0.5 part Thickener, 20~23 parts of moisturizer, 0.1~0.2 part of hyaluronic acid, 0.3~1 part of biological carbohydrate gum -1,0.1~0.4 part of six victory Peptide -9,1~5 part of beta glucan, 0.1~0.2 portion of preservative, 1~2 part of anti-sensitizer, surplus is water.
2. tender skin water light stoste according to claim 1, it is characterised in that the thickener is Carbopol 941 and Ka Bo Nurse 940.
3. tender skin water light stoste according to claim 3, it is characterised in that the Carbopol 941 and Acritamer 940 according to Mass ratio is(1.5~3):1 mixing.
4. tender skin water light stoste according to claim 1, it is characterised in that the moisturizer be by polyalcohol, fucose, The composition that glycine betaine and ethoxy urea are obtained by mixing, wherein the polyalcohol is 1,2-PD, 1,3-BDO or third One or more combinations in triol.
5. tender skin water light stoste according to claim 4, it is characterised in that the polyalcohol, fucose, glycine betaine, hydroxyl Ethyl carbamide mixed proportion is by mass:(6~12):(1~3):(1~4):(1~5).
6. tender skin water light stoste according to claim 4, it is characterised in that Sodium Hyaluronate is 1,300,000 dalton molecules It is measuring to be mixed with 500,000 Dalton molecular weights Sodium Hyaluronates.
7. tender skin water light stoste according to claim 6, it is characterised in that the hyaluronic acid of 1,300,000 Dalton molecular weights The Sodium Hyaluronate mass ratio of sodium and 500,000 Dalton molecular weights is 1.5~3:1.
8. tender skin water light stoste according to claim 1, it is characterised in that the anti-sensitizer is graceful for antiallergic antipruritic and Austria Quick, dipotassium glycyrrhizinate mixes;The antiallergic antipruritic is hanfangchin A or tetrandrine or tetrandrine;
It is preferred that the anti-sensitizer for antiallergic antipruritic with graceful quick, dipotassium glycyrrhizinate difficult to understand with 10:5:1 ratio mixes.
9. the preparation method of any one of the claim 1~8 tender skin water light stoste, it is characterised in that comprise the following steps:
S1. with sterile water dissolving moisturizer, Sodium Hyaluronate and thickener, dissolve by heating and keep the temperature homogeneous;
S2. the pH value of system obtained by regulating step S1 is 5.5~6.5;
S3. system obtained by step S2 is cooled to less than 45 DEG C,
S4. biological carbohydrate gum -1, Argireline -9, beta glucan, preservative, anti-sensitizer are added into system obtained by step S3, at a slow speed Stir evenly up to the tender skin water light stoste;
Heating is heated to 70~95 DEG C described in preferred steps S1, and time of homogeneous be 1~5min, and time of insulation is 10~ 30min;
PH value agents useful for same is adjusted described in preferred steps S2 as triethanolamine, sodium hydroxide, potassium hydroxide, citric acid, citric acid The one or more of sodium, tartaric acid, sodium tartrate, phytic acid or acetic acid etc..
10. the application of any one of claim 1 to the 9 tender skin water light stoste, it is characterised in that applied to moisturizing can be used as The raw material or skin matrix of crease-resistant class cosmetics.
CN201710940913.5A 2017-10-10 2017-10-10 A kind of tender skin water light stoste and its preparation method and application Pending CN107898660A (en)

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CN108478519A (en) * 2018-04-23 2018-09-04 广州雷诺生物科技有限公司 A kind of fossil water light stoste containing fullerene
CN109394645A (en) * 2018-12-14 2019-03-01 广州润虹医药科技股份有限公司 A kind of painting type water laser accunputure essence and preparation method thereof
CN110251423A (en) * 2019-07-22 2019-09-20 陕西佰傲再生医学有限公司 A kind of skin care compositions and preparation method thereof
CN110314130A (en) * 2019-08-13 2019-10-11 广州海梦科化妆品有限公司 Stoste and preparation method thereof is repaired in a kind of whitening
CN110638701A (en) * 2019-08-30 2020-01-03 美肌化妆品有限公司 Shuangguang soothing toning lotion and preparation method thereof
CN111012729A (en) * 2020-01-13 2020-04-17 南京平港健康管理有限公司 Hyaluronic acid anti-wrinkle stock solution
CN111495248A (en) * 2020-04-21 2020-08-07 江苏更美科技有限公司 Preparation method, device and application of water-light stock solution with effect of enhancing skin tendering and water replenishing
CN111888309A (en) * 2020-08-14 2020-11-06 广州致美日化科技有限公司 Water acupuncture cream composition
CN112791038A (en) * 2020-03-05 2021-05-14 上海友仁生物科技有限公司 Cosmetic composition for anti-allergy repair and preparation method thereof
WO2024035908A1 (en) * 2022-08-12 2024-02-15 Colgate-Palmolive Company Personal care compositions

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CN105380819A (en) * 2015-11-18 2016-03-09 中山市艾丽意素生物科技有限公司 Moisturized and compact basic essence and preparation method thereof
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Publication number Priority date Publication date Assignee Title
CN108478519A (en) * 2018-04-23 2018-09-04 广州雷诺生物科技有限公司 A kind of fossil water light stoste containing fullerene
CN109394645A (en) * 2018-12-14 2019-03-01 广州润虹医药科技股份有限公司 A kind of painting type water laser accunputure essence and preparation method thereof
CN110251423A (en) * 2019-07-22 2019-09-20 陕西佰傲再生医学有限公司 A kind of skin care compositions and preparation method thereof
CN110314130A (en) * 2019-08-13 2019-10-11 广州海梦科化妆品有限公司 Stoste and preparation method thereof is repaired in a kind of whitening
CN110638701A (en) * 2019-08-30 2020-01-03 美肌化妆品有限公司 Shuangguang soothing toning lotion and preparation method thereof
CN111012729A (en) * 2020-01-13 2020-04-17 南京平港健康管理有限公司 Hyaluronic acid anti-wrinkle stock solution
CN112791038A (en) * 2020-03-05 2021-05-14 上海友仁生物科技有限公司 Cosmetic composition for anti-allergy repair and preparation method thereof
CN111495248A (en) * 2020-04-21 2020-08-07 江苏更美科技有限公司 Preparation method, device and application of water-light stock solution with effect of enhancing skin tendering and water replenishing
CN111495248B (en) * 2020-04-21 2021-07-23 江苏更美科技有限公司 Preparation method, device and application of water-light stock solution with effect of enhancing skin tendering and water replenishing
CN111888309A (en) * 2020-08-14 2020-11-06 广州致美日化科技有限公司 Water acupuncture cream composition
WO2024035908A1 (en) * 2022-08-12 2024-02-15 Colgate-Palmolive Company Personal care compositions

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