CN107822946A - A kind of painting type water light porcelain flesh Essence and preparation method thereof - Google Patents

A kind of painting type water light porcelain flesh Essence and preparation method thereof Download PDF

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Publication number
CN107822946A
CN107822946A CN201710940912.0A CN201710940912A CN107822946A CN 107822946 A CN107822946 A CN 107822946A CN 201710940912 A CN201710940912 A CN 201710940912A CN 107822946 A CN107822946 A CN 107822946A
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CN
China
Prior art keywords
type water
water light
painting type
light porcelain
skin
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Pending
Application number
CN201710940912.0A
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Chinese (zh)
Inventor
杨菊
曹波
黄振振
刘运花
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KINGWAY COSMETICS TECHNOLOGY GUANGZHOU CO., LTD.
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Guangzhou Bailichen Cosmetics Co Ltd
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Priority to CN201710940912.0A priority Critical patent/CN107822946A/en
Publication of CN107822946A publication Critical patent/CN107822946A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Abstract

The invention discloses a kind of painting type water light porcelain flesh Essence and preparation method thereof.Described painting type water light porcelain flesh Essence is composed of the following components by mass:0.1~0.5 portion of stable thickener, 10~15 parts of NMFs, 0.3~0.8 part of emulsifying agent, 0.03~0.1 part of hyaluronic acid, 0.03~1.0 part of biological polyoses glue, 0.15~0.3 part of allantoin, 0.5~1.5 part of saualane, 0.08~0.15 part of dipotassium glycyrrhizinate, 1~3 part of beta glucan, 0.2~0.4 part of anti-sensitizer, 2~3 parts of DC345,1~5 part of yeast brilliant white elite, 2 portions of preservatives, surplus is sterilized water.Water light porcelain flesh Essence of the present invention infiltrates into skin skin corium through smearing, and quick moisturizing, long-acting water lock, pore refining, improvement relaxation can be achieved, desalinate microgroove, and fair-skinned bright, the skin that compacts remarkable result.

Description

A kind of painting type water light porcelain flesh Essence and preparation method thereof
Technical field
The present invention relates to technical field of skin care, more particularly, to a kind of painting type water light porcelain flesh Essence and its Preparation method.
Background technology
In recent years, the skin-protection product for possessing various effects constantly updates iteration, welcomes the fast development of cosmetic industry, but Due to the deterioration of environment, the external cause such as ultraviolet problem bursts out caused by quality problem, air problem, depletion of the ozone layer, plus drink The deterioration of food work and rest custom, suppress under the internal cause such as psychological condition emerge in large numbers, the requirement for skin care item also constantly rises.Industry Studying core, around moisturizing, this basic problem is carried out all the time, is researched and developed a kind of quick moisturizing of energy and is continued the skin-protection product of water lock As the joint demand of consumer.
The water laser accunputure occurred therewith on the market has obtained the favor of consumer, the quick moisturizing of water laser accunputure energy, reaches skin The effect of " water light jade-like stone profit ".But the use of water laser accunputure belongs to minor operation, has the disadvantage that, one, using highly inconvenient, it is necessary to The micro-shaping doctor operation of specialty, needs to anaesthetize before use;Secondly, the skin with acne, acne or wound easily occurred It is quick, it is impossible to use;Thirdly, it is postoperative different degrees of inflamed situation can occur, therefore postoperative two celestial poles easy infection is, it is necessary to spy Different nursing, influences normal life, in addition, water laser accunputure price is high in the short time, it is impossible to used in most of consumer.
The content of the invention
The technical problem to be solved in the present invention is the demand and existing water laser accunputure for the quick moisturizing nursing of consumer skin Application limitation, there is provided a kind of painting type water light porcelain flesh Essence.
Another technical problems to be solved of the present invention are to provide the preparation method of the Essence.
The purpose of the present invention is achieved through the following technical solutions:
A kind of painting type water light porcelain flesh Essence is provided, according to 100 parts of meters of mass fraction, including:0.1~0.5 part of stabilization Thickener, 10~15 parts of NMFs, 0.3~0.8 part of emulsifying agent, 0.03~0.1 part of hyaluronic acid, 0.03~1.0 part of biology are more Carbohydrate gum, 0.15~0.3 part of allantoin, 0.5~1.5 part of saualane, 0.08~0.15 part of dipotassium glycyrrhizinate, 1~3 part of beta glucan, 0.2~0.4 part of anti-sensitizer, 2~3 parts of DC345,1~5 part of yeast brilliant white elite, 2 portions of preservatives, surplus is water.
The water is the water that skin care item or Cosmetic Manufacture allow to use, including sterilized water or deionized water or purified water Deng.
Preferably, described stable thickener is carbomer U21.
Preferably, described emulsifying agent is lecithin.
Preferably, described preservative be methyl hydroxybenzoate and liquid germall plus mixture, further it is excellent The two geological measuring ratio of choosing is 3:1.
Preferably, described NMF be by 1,3-PD, glycerine, glycine betaine, fucose, reed fragrant plant oil mixing and Into by mass, ratio is 1,3-PD to its proportion of composing:Glycerine:Glycine betaine:Fucose:Reed fragrant plant oil is 3~5:1~ 3:1~3:1~2:1~2;
Described anti-sensitizer can use anti-sensitizer commonly used in the art.Preferably, described anti-sensitizer can be with Using trade name graceful quick anti-sensitizer difficult to understand, extract, have good through 35 kinds of lactobacillus fermentations using plant soya-bean milk as raw material Good antiallergy effect.
Preferably, described hyaluronic acid is 500,000 Dalton molecular weight ranks, can be preferably with other components of the present invention Cooperate with and through smearing energy rapid osmotic to skin skin corium.
Described biological polyoses glue is obtained through soybean or corn fermentation, or obtained by both co-fermentations, or corn and soybean Mixed after fermenting respectively with arbitrary proportion.
Invention also provides the preparation method of the painting type water light porcelain flesh Essence, comprise the following steps:
S1. NMF, allantoin, hyaluronic acid, emulsifying agent, thickener are added in sterilized water, dissolved by heating, form nothing The homogeneous system of particle, cool after being incubated 20~40min;
S2. saualane is dissolved with 2~3 parts of DC345 (silicone oil), the body that the saualane after dissolving is added after step S1 coolings In system, homogenization;
S3. the system temperature after step S2 homogenizations is reduced to 25~50 DEG C, and regulation system pH value is 5~7.5;
S4. yeast brilliant white Essence, beta glucan, biological polyoses glue, dipotassium glycyrrhizinate and anti-sensitizer are added, is stirred Produce.
Preferably, 75~90 DEG C are heated to during heating described in step S1;The cooling is to be down to 50~70 DEG C.
Preferably, the time of homogenization described in step S2 is 3~8min.
The pH adjusting agent that the pH of step S3 regulation systems is used is triethanolamine (TEA).
Beneficial effects of the present invention are as follows:
The present invention moistens the deficiency of skin technology for existing moisturizing jade-like stone, and the present invention is made using biological polyoses glue and hyaluronic acid For main active component rational proportion compatibility, compound moisturizing water lock is realized, is sent out jointly with other active components and auxiliary element Synergy is waved, quick moisturizing, continues water lock, penetrating skin, imports skin corium, the painting type water light elite for exempting from injection is made Liquid, it is equipped with anti-allergic agent effect and solves the problems such as inconvenient for use, side effect is big emphatically, played water laser accunputure advantage and overcome The limitation of water laser accunputure use.
There is Essence of the present invention silk to slide salubrious pleasant skin sense, quick moisturizing can be realized, described in invention Biological polyoses glue cooperates with hyaluronic acid complementation, forms skin care barrier, realizes long-acting water lock moisturizing, and various active composition produces increasing Effect acts on, and not only promotes moisturizing, and adjusts inflammation, suppresses allergy, promotes the differentiation of horn cell, repair and activate inferior health The skin cell of state, increase skin elasticity and gloss, substitute the quick moisturizing of water laser accunputure, make skin reach " water light jade-like stone profit ", as The effect of ceramics equally smooth " water light porcelain flesh ".Verify after tested, the present invention is safe and reliable, moisturizing can be used as to repair class skin care Liquid is long-term use of.
Brief description of the drawings
Skin moisture content comparing result before and after Fig. 1 painting type water light porcelain flesh elite uses of the present invention.
Skin complexion comparing result before and after Fig. 2 painting type water light porcelain flesh elite uses of the present invention.
Skin complexion comparing result before and after Fig. 3 painting type water light porcelain flesh elite uses of the present invention.
Embodiment
The present invention is further illustrated with reference to specific embodiment.Following being given for example only property of embodiment explanations, it is impossible to manage Solve as limitation of the present invention.Unless stated otherwise, the raw material used in following embodiments is that conventional purchased in market or commercial sources obtain The raw material obtained, unless stated otherwise, the method and apparatus used in following embodiments are method commonly used in the art and set It is standby.
For convenience of description, heretofore described primary raw material, wherein the producer illustrated does not limit the present invention, ability Domain can also use the similar products of other manufacturer productions based on compatibility thought of the present invention:
Hyaluronic acid, also known as sodium hyaluronate, No. CAS:9004-61-9, its structure are as follows:
Biological polyoses glue, No. CAS:283602-75-5, its structural formula are as follows:
Biological polyoses glue mainly contains L-fucose, D- galactolipins and galacturonic acid.Excipients are used as in the present invention With active component application, the moisture barrier of skin on the one hand in skin surface film forming, can be strengthened, improve cosmetics skin sense;It is another Aspect allows active component to play the activity of good suppression inflammation and allergy jointly with it, helps keratinocyte differentiation, survival, prolongs Slow aging.
Lecithin, No. CAS:8002-43-5, its structural formula are as follows;
Fucose, No. CAS:2438-80-4, its structural formula are as follows:
Glycine betaine, No. CAS:107-43-7, its structural formula are as follows:
Saualane, No. CAS:111-01-3, its structural formula are as follows:
Allantoin, CAS 97-59-6, its structural formula are as follows:
Allantoin is a kind of hydantoin derivatives as made from glyoxalic acid, urea synthesizing, and allantoin can promote cell to give birth to Long, quickening wound healing, cutin-softening albumen simultaneously alleviate xerodermia, and in the present invention, it is just right that allantoin can play Sterilization and anticorrosion, nourish moisturizing, it is anti-oxidant convergence etc. multi-efficiency.
Dipotassium glycyrrhizinate, No. CAS:68797-35-3, its structural formula are as follows:
Dipotassium glycyrrhizinate is radix glycyrrhizae through, with composition the effect of acquisition, extensively having in medicine food and household chemicals field should in water extraction With, in the present invention, antibacterial removing toxic substances, anti-inflammatory antiallergic and other effects are played, and activation corticosteroid compound can be played, prevent from making up The effect of product allergic reaction, promote the absorption of skin care item, collaboration strengthens its effect.
Beta glucan, No. CAS:160872-27-5.Beta glucan forms the poly- of active structure to be a kind of by glucose monomer Compound homopolysaccharide, it can stimulate body immune system by activated macrophage, neutrophils etc., promote immunity of organism Cascade reaction, barrier anaphylactogen, suppress the release of histamine and sensitization IgE immunoglobulins, at the same induce EGF, TNF-α, AF and The generation of the interferon such as bFGF, realize the quick renewal of damaging cells tissue with recovering.In the present invention, beta glucan is played and carried High immunity, skin trauma effect is repaired, and removes free radical, improves EGF (EGF) and moisturizing factor content, The effect of reaching moisturizing, crease-resistant, anti-aging and synergy.
Anti-sensitizer of the present invention can use existing anti-sensitizer commonly used in the art.Preferably, trade name can be used For the anti-sensitizer of booth difficult to understand quick (difficult to understand graceful quick), sources refer to websitewww.axialys-innovations.comUpper disclosure Information.The anti-sensitizer main composition is the filtrate of Bacillus acidi lactici and soya-bean milk tunning, inner protein, amino acid, more The various active composition such as peptide, phosphatide, brass.The present invention by many experiments find its with present invention determine that other components can Play synergy well, suppress the growing of harmful bacteria, reduce skin pain caused by extraneous infringement immediately, suppress or Allergic reaction etc. of releiving is complemented each other with other components of the present invention.
Yeast brilliant white elite (is purchased from Guangzhou Tai Mao trade Co., Ltds), is that yeast cells extracts after broken wall and arrives albumen Matter, nucleic acid, vitamin etc., then mixed through biological enzymolysis into rich in natural activities such as small molecule amino acid, peptide, nucleotides, vitamins Synthesis point.With nourishes rough skin, anti-aging, the tender white notable function such as skin thoroughly.
Lu fragrant plant oil, No. CAS:56-81-5,9003-01-4,57-55-6,9011-16-9, by the son extraction of Fan Luo Portugals Water soluble humectants, it is polyacrylic acid, methyl vinyl ether-maleic acid copolymer, propane diols, the mixture of glycerine.At this Moisturizing lubricant is used as in invention, splendid gloss and soft and smooth skin sense are provided for skin.
Embodiment 1
Each raw material is weighed according to mass parts:0.1 part of stable thickener, 15 parts of NMFs, 0.5 part of emulsifying agent, 0.1 part it is transparent Matter acid, 0.03~1.0 part of biological polyoses glue, 0.15~0.3 part of allantoin, 0.5~1.5 part of saualane, 0.08 part of glycyrrhizic acid two Potassium, 2.5 parts of beta glucans, 0.3 part of anti-sensitizer, 2 parts of DC345,3 parts of yeast brilliant white elite, 2 portions of preservatives, surplus is sterilized water.
Described anti-sensitizer is graceful quick (being purchased from French celestial graceful) difficult to understand, is extracted through plant fermentation, has antiallergy effect.
Described hyaluronic acid is commercially available 500,000 molecular weight grades product, through smearing energy rapid osmotic to skin skin corium.
Described biological polyoses glue obtains purchased from plain Lai Biya companies of France via soybean and corn co-fermentation.
Described emulsifying agent is lecithin.
Described NMF is mixed by 1,3-PD, glycerine, glycine betaine, fucose, reed fragrant plant oil, and it is formed Ratio by mass, 1,3-PD:Glycerine:Glycine betaine:Fucose:Reed fragrant plant oil is 5:3:3:2:2.
Described painting type water light porcelain flesh elite liquid and preparation method thereof, comprises the following steps:
S1. NMF, allantoin, hyaluronic acid, emulsifying agent, thickener are added in sterilized water, dissolved by heating, form nothing The homogeneous system of particle, it is incubated 30min;
S2. add with the saualane that 2 parts of DC345 have dissolved in emulsification pot, homogeneous 3min.
S3. system temperature is reduced to 25 DEG C, and is 5 with TEA regulation systems pH value.
S4. yeast brilliant white elite, beta glucan, biological polyoses glue, dipotassium glycyrrhizinate and anti-sensitizer are added, is stirred i.e. .
100 voluntary triers of women, at 18~50 years old age, it is divided into two groups, one group is blank group, does not smear any elite Liquid, one group is smeared the present embodiment product (once in the morning and once at night) daily, is during which then terminated if the adverse reactions such as allergy occurs in 1 people Experiment, does not as a result find adverse reaction.To exclude the interference of the effect of other functional cosmetics and medicine, tested sample is being tested Period without using other medicines or functional cosmetics, after the present embodiment product 28d is used continuously, surveys to subjects skin Examination, as a result display use the test group of the present embodiment product to compare blank group, skin water light jade-like stone profit, continue in terms of moisturizing to have substantially Effect, shunk using the test group skin pore of the present embodiment product, compacted, highlight for the use of be clearly distinguishable from contrast and examination The person of testing uses the effect before this product.
Embodiment 2
Each raw material is weighed according to mass parts:0.2 part of stable thickener, 11 parts of NMFs, 0.8 part of emulsifying agent, 0.08 part thoroughly Bright matter acid, 1.0 parts of biological polyoses glue, 0.2 part of allantoin, 0.8 part of saualane, 0.12 part of dipotassium glycyrrhizinate, 3 parts of beta glucans, 0.4 part of anti-sensitizer, 3 parts of DC345,1 part of yeast brilliant white elite, 2 portions of preservatives, surplus is sterilized water.
Described hyaluronic acid is 500,000 Dalton molecular weight ranks, through smearing energy rapid osmotic to skin skin corium.
Described biological polyoses glue obtains through fermented soybean.
Described emulsifying agent is lecithin.
Described NMF is mixed by 1,3-PD, glycerine, glycine betaine, fucose, reed fragrant plant oil, and it is formed Ratio by mass, the propane diols of ratio 1,3:Glycerine:Glycine betaine:Fucose:Reed fragrant plant oil is 3:3:2:2:1.
Described painting type water light porcelain flesh elite liquid and preparation method thereof, comprises the following steps:
S1. NMF, allantoin, hyaluronic acid, emulsifying agent, thickener are added in sterilized water, dissolved by heating, form nothing The homogeneous system of particle, it is incubated 40min.
S2. add with the saualane that 3 parts of DC345 have dissolved in emulsification pot, homogeneous 4min.
S3. system temperature is reduced to 35 DEG C, and is 7 with TEA regulation systems pH value.
S4. yeast brilliant white elite, beta glucan, biological polyoses glue, dipotassium glycyrrhizinate and anti-sensitizer are added, is stirred i.e. .
100 voluntary triers of women, at 18~50 years old age, it is divided into two groups, one group is blank group, does not smear any elite Liquid, one group is smeared the present embodiment product (once in the morning and once at night) daily, is during which then terminated if the adverse reactions such as allergy occurs in 1 people Experiment, does not as a result find adverse reaction.To exclude the interference of the effect of other functional cosmetics and medicine, tested sample is being tested Period without using other medicines or functional cosmetics, after the present embodiment product 28d is used continuously, surveys to subjects skin Examination, as a result display use the test group of the present embodiment product to compare blank group, skin water light jade-like stone profit, continue in terms of moisturizing to have substantially Effect, shunk using the test group skin pore of the present embodiment product, compacted, highlight for the use of be clearly distinguishable from contrast and examination The person of testing uses the effect before this product.
Embodiment 3
It is made up of following mass parts raw materials:0.5 part of stable thickener, 10 parts of NMFs, 0.6 part of emulsifying agent, 0.05 part thoroughly Bright matter acid, 0.03 part of biological polyoses glue, 0.25 part of allantoin, 1 part of saualane, 0.1 part of dipotassium glycyrrhizinate, 2 parts of beta glucans, 0.3 Part anti-sensitizer, 3 parts of DC345,4 parts of yeast brilliant white elite, 2 portions of preservatives, surplus is sterilized water.
Described anti-sensitizer is difficult to understand graceful quick, is extracted through plant fermentation, has antiallergy effect.
Described hyaluronic acid is 500,000 Dalton molecular weight ranks, through smearing energy rapid osmotic to skin skin corium.
Described biological polyoses glue obtains through corn fermentation.
Described NMF is mixed by 1,3-PD, glycerine, glycine betaine, fucose, reed fragrant plant oil, and it is formed Ratio by mass, the propane diols of ratio 1,3:Glycerine:Glycine betaine:Fucose:Reed fragrant plant oil is 4:2:2:1:1.
Described painting type water light porcelain flesh elite liquid and preparation method thereof, comprises the following steps:
S1. NMF, allantoin, hyaluronic acid, emulsifying agent, thickener are added in sterilized water, dissolved by heating, form nothing The homogeneous system of particle, it is incubated 25min.
S2. add with the saualane that 3 parts of DC345 have dissolved in emulsification pot, homogeneous 6min.
S3. system temperature is reduced to 40 DEG C, and is 7 with TEA regulation systems pH value.
S4. yeast brilliant white elite, beta glucan, biological polyoses glue, dipotassium glycyrrhizinate and anti-sensitizer are added, is stirred i.e. .
100 voluntary triers of women, at 18~50 years old age, it is divided into two groups, one group is blank group, does not smear any elite Liquid, one group is smeared the present embodiment product (once in the morning and once at night) daily, is during which then terminated if the adverse reactions such as allergy occurs in 1 people Experiment, does not as a result find adverse reaction..To exclude the interference of the effect of other functional cosmetics and medicine, tested sample is being tried Without using other medicines or functional cosmetics during testing, after the present embodiment product 28d is used continuously, subjects skin is carried out Test, as a result show and compare blank group using the test group of the present embodiment product, skin water light jade-like stone profit, the moisturizing aspect that continues have bright Aobvious effect, shunk using the test group skin pore of the present embodiment product, compacted, highlight for the use of be clearly distinguishable from contrast and Experimenter uses the effect before this product.
Embodiment 4
It is made up of following mass parts raw materials:0.3 part of stable thickener, 13 parts of NMFs, 0.3 part of emulsifying agent, 0.03 part thoroughly Bright matter acid, 0.05 part of biological polyoses glue, 0.15 part of allantoin, 0.5 part of saualane, 0.08 part of dipotassium glycyrrhizinate, 1 part of beta glucan, 0.2 part of anti-sensitizer, 2 parts of DC345,5 parts of yeast brilliant white elite, 2 portions of preservatives, surplus is sterilized water.
Described anti-sensitizer is difficult to understand graceful quick, is extracted through plant fermentation, has antiallergy effect.
Described hyaluronic acid is 500,000 Dalton molecular weight ranks, through smearing energy rapid osmotic to skin skin corium.
Described biological polyoses glue obtains through corn fermentation.
Described NMF is mixed by 1,3-PD, glycerine, glycine betaine, fucose, reed fragrant plant oil, and it is formed By mass, ratio is 1,3-PD to ratio:Glycerine:Glycine betaine:Fucose:Reed fragrant plant oil is 4:2:3:2:2.
Described painting type water light porcelain flesh elite liquid and preparation method thereof, comprises the following steps:
S1. NMF, allantoin, hyaluronic acid, emulsifying agent, thickener are added in sterilized water, dissolved by heating, form nothing The homogeneous system of particle, it is incubated 20min.
S2. add with the saualane that 2 parts of DC345 have dissolved in emulsification pot, homogeneous 8min.
S3. system temperature is reduced to 50 DEG C, and is 7.5 with TEA regulation systems pH value.
S4. yeast brilliant white Essence, beta glucan, biological polyoses glue, dipotassium glycyrrhizinate and anti-sensitizer are added, is stirred Produce.
100 voluntary triers of women, at 18~50 years old age, it is divided into two groups, one group is blank group, does not smear any elite Liquid, one group is smeared the present embodiment product (once in the morning and once at night) daily, is during which then terminated if the adverse reactions such as allergy occurs in 1 people Experiment, does not as a result find adverse reaction.To exclude the interference of the effect of other functional cosmetics and medicine, tested sample is being tested Period without using other medicines or functional cosmetics, after the present embodiment product 28d is used continuously, surveys to subjects skin Examination, as a result display use the test group of the present embodiment product to compare blank group, skin water light jade-like stone profit, continue in terms of moisturizing to have substantially Effect, shunk using the test group skin pore of the present embodiment product, compacted, highlight for the use of be clearly distinguishable from contrast and examination The person of testing uses the effect before this product.
To exempt to repeat, the present invention randomly selects any one group of Experimental comparison results' displaying from the contrast test person of embodiment 1 to 4 As depicted in figs. 1 and 2.Fig. 1 show skin moisture content comparing result before and after painting type water light porcelain flesh elite use of the present invention. From comparing result, improve almost one times using skin moisture content after product of the present invention and (be promoted to by 25% 45%).Before and after painting type water light porcelain flesh elite use of the present invention shown in Fig. 2 and Fig. 3 (in Fig. 2 and Fig. 3, left figure be before use, After right figure is use) skin complexion comparing result, is shunk using the obvious pore of rear skin, compacted, the colour of skin highlights.

Claims (10)

  1. A kind of 1. painting type water light porcelain flesh Essence, it is characterised in that according to 100 parts of meters of mass fraction, including:0.1~0.5 part Stable thickener, 10~15 parts of NMFs, 0.3~0.8 part of emulsifying agent, 0.03~0.1 part of hyaluronic acid, 0.03~1.0 part of life Thing polysaccharide gum, 0.15~0.3 part of allantoin, 0.5~1.5 part of saualane, 0.08~0.15 part of dipotassium glycyrrhizinate, 1~3 part of β Portugal Glycan, 0.2~0.4 part of anti-sensitizer, 2~3 parts of DC345,1~5 part of yeast brilliant white elite, 2 portions of preservatives, surplus is water.
  2. 2. painting type water light porcelain flesh Essence according to claim 1, it is characterised in that described stable thickener is card Ripple nurse U21.
  3. 3. painting type water light porcelain flesh Essence according to claim 1, it is characterised in that described NMF is by 1,3- Propane diols, glycerine, glycine betaine, fucose, reed fragrant plant oil mix, its proportion of composing by mass, ratio 1,3- the third two Alcohol:Glycerine:Glycine betaine:Fucose:Reed fragrant plant oil is 3~5:1~3:1~3:1~2:1~2.
  4. 4. painting type water light porcelain flesh Essence according to claim 1, it is characterised in that described emulsifying agent is lecithin Fat.
  5. 5. painting type water light porcelain flesh Essence according to claim 1, it is characterised in that described preservative is oxybenzene first The mixture of ester and liquid germall plus;It is preferred that the mass ratio of the methyl hydroxybenzoate and liquid germall plus Example is 3:1.
  6. 6. painting type water light porcelain flesh Essence according to claim 1, it is characterised in that the anti-sensitizer is difficult to understand graceful quick.
  7. 7. painting type water light porcelain flesh Essence according to claim 1, it is characterised in that the hyaluronan molecule amount is 500000 dalton.
  8. 8. the preparation method of the painting type water light porcelain flesh Essence according to any one of claim 1~7, it is characterised in that Comprise the following steps:
    S1. NMF, allantoin, hyaluronic acid, emulsifying agent, thickener are added in sterilized water, dissolves by heating, form no particle Homogeneous system, be incubated 20~40min after cool;
    S2. saualane is dissolved with 2~3 parts of DC345, the saualane dissolved is added in the system after step S1 coolings, homogeneous Processing;
    S3. reduce the system temperature after step S2 homogenizations and be down to 25~50 DEG C, and regulation system pH value is 5~7.5;
    S4. yeast brilliant white Essence, beta glucan, biological polyoses glue, dipotassium glycyrrhizinate and anti-sensitizer are added, is stirred i.e. .
  9. 9. preparation method according to claim 8, it is characterised in that be heated to 75~90 DEG C during heating described in step S1; The cooling is to be down to 50~70 DEG C.
  10. 10. preparation method according to claim 8, it is characterised in that the time of homogenization described in step S2 be 3~ 8min;PH adjusting agent used in step S2 regulation systems pH is TEA.
CN201710940912.0A 2017-10-10 2017-10-10 A kind of painting type water light porcelain flesh Essence and preparation method thereof Pending CN107822946A (en)

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CN108272741A (en) * 2018-03-30 2018-07-13 广州科盈化妆品有限公司 A kind of anti-wrinkle essence breast and preparation method thereof
CN109224114A (en) * 2018-10-10 2019-01-18 广州润虹医药科技股份有限公司 A kind of foam dressing and its preparation method and application
CN109394645A (en) * 2018-12-14 2019-03-01 广州润虹医药科技股份有限公司 A kind of painting type water laser accunputure essence and preparation method thereof
CN109700739A (en) * 2019-02-25 2019-05-03 江苏煦音生物科技有限公司 A kind of taste face cream formula and its configuration method
CN110547980A (en) * 2018-06-04 2019-12-10 广州市惠芳日化有限公司 Skin conditioner with water supplementing and moisturizing effects, moisturizing lotion and preparation method thereof
CN113274335A (en) * 2021-05-18 2021-08-20 云南贺尔思细胞生物技术有限公司 Skin repair liquid based on umbilical cord mesenchymal stem cell factor and preparation method thereof
CN113350212A (en) * 2021-07-19 2021-09-07 广州新妆生物科技有限公司 Natural brightening essence and preparation method thereof
CN113768859A (en) * 2021-06-23 2021-12-10 仙婷(广州)科技研发有限公司 Oral and external composition for improving sensitive skin and application thereof
CN115501126A (en) * 2022-11-01 2022-12-23 梅晔生物医药股份有限公司 Whitening anti-wrinkle composition and daily chemical

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Publication number Priority date Publication date Assignee Title
CN108272741A (en) * 2018-03-30 2018-07-13 广州科盈化妆品有限公司 A kind of anti-wrinkle essence breast and preparation method thereof
CN110547980A (en) * 2018-06-04 2019-12-10 广州市惠芳日化有限公司 Skin conditioner with water supplementing and moisturizing effects, moisturizing lotion and preparation method thereof
CN109224114A (en) * 2018-10-10 2019-01-18 广州润虹医药科技股份有限公司 A kind of foam dressing and its preparation method and application
CN109224114B (en) * 2018-10-10 2021-06-04 广州润虹医药科技股份有限公司 Foam dressing and preparation method and application thereof
CN109394645A (en) * 2018-12-14 2019-03-01 广州润虹医药科技股份有限公司 A kind of painting type water laser accunputure essence and preparation method thereof
CN109700739A (en) * 2019-02-25 2019-05-03 江苏煦音生物科技有限公司 A kind of taste face cream formula and its configuration method
CN113274335A (en) * 2021-05-18 2021-08-20 云南贺尔思细胞生物技术有限公司 Skin repair liquid based on umbilical cord mesenchymal stem cell factor and preparation method thereof
CN113768859A (en) * 2021-06-23 2021-12-10 仙婷(广州)科技研发有限公司 Oral and external composition for improving sensitive skin and application thereof
CN113350212A (en) * 2021-07-19 2021-09-07 广州新妆生物科技有限公司 Natural brightening essence and preparation method thereof
CN115501126A (en) * 2022-11-01 2022-12-23 梅晔生物医药股份有限公司 Whitening anti-wrinkle composition and daily chemical

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