CN105902408A - Cosmetic composition containing brown algae and red algae essence - Google Patents
Cosmetic composition containing brown algae and red algae essence Download PDFInfo
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- CN105902408A CN105902408A CN201510621942.6A CN201510621942A CN105902408A CN 105902408 A CN105902408 A CN 105902408A CN 201510621942 A CN201510621942 A CN 201510621942A CN 105902408 A CN105902408 A CN 105902408A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/12—Face or body powders for grooming, adorning or absorbing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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Abstract
The invention relates to a cosmetic composition containing brown algae and red algae essence. The cosmetic composition contains alginate oligosaccharide and red algae oligosaccharide. The invention also comprises a method for improving moisture retention effects of the cosmetic composition. The method comprises use of alginate oligosaccharide and red algae oligosaccharide in the cosmetic composition. The cosmetic composition has moisture retention effects on the skin surface, has excellent properties of skin-friendly, can provide second skin effects for the skin, has skin regeneration effects on the deep skin, improves deep epidermis hyaluronic acid content, activates tight junction protein 1 synthesis, improves intercellular tight junction, improves ceramide synthesis and improves a lipid barrier.
Description
Technical field
The invention belongs to cosmetic field, be specifically related to containing Brown algae and the cosmetic composition of red algae elite.
Background technology
Moist and elastic and in skin the moisture of skin has substantial connection, when the moisture excess in skin is lost
Time, can cause xerosis cutis, follow the string, accelerated ageing.Therefore moisture absorption, moisturizing are always cosmetic skin-care
One of effect of product.Preferably wetting agent should possess good wettability power, and moisture-keeping functions is persistently stablized.
Natural polysaccharide is with a wide range of applications on cosmetics.Such as chitin, fucoidin, Cornu Cervi
Dish glue, mucopolysaccharide, fucoidin etc. have the effects such as nutrition, reparation and moisturizing.The moisturizing of polysaccharide material,
Moisture absorption mechanism is owing to containing substantial amounts of hydrophilic group in molecule, and hydrogen bond can be become to combine big with associated water molecules
The moisture of amount, and glycan molecule is interweaved in netted, forms thin film on surface, plays water retention.
And after polysaccharide is degraded to oligosaccharide, along with the fracture of glycosidic bond, substantial amounts of free hydroxyl group is released,
The ability of its bound water molecule can strengthen, further, since during molecular breakdown, molecular structure becomes loose condition (of surface),
It is more beneficial for the close of hydrone.Therefore, oligosaccharide often has a more excellent moisture pick-up properties, but oligosaccharide
Moisture retention because cancellated partial destruction can weaken.
Natural polysaccharide or oligosaccharide are isolated from algae.According to color classification, algae be divided into cyanophyceae, red algae,
Chlorella and Brown algae.Many algae have been used as a part for cosmetics for health & beauty.
Such as, CN200780039713.7 discloses a kind of ocean oligosaccharide in cosmetics and biology is sent out
Ferment thing, is specifically related to a kind of cosmetic composition, comprises Sarcodiotheca oligosaccharide and cosmetics can connect
The excipient being subject to.S.gaudichaudii is medium-sized to large-scale flaccid red alga species, has cylinder
Frangible frond；Color can change between pale pink color, peony or rufous faint yellow.Once receive
Obtain, the oligomeric of Sarcodiotheca can be produced by any extracting method well known by persons skilled in the art
Sugar, preferred oligosaccharide is the aqueous oligosaccharide of the whole plants from dehydration.
CN201110341261.6 discloses a kind of water-replenishing repairing cosmetic and its preparation method and application, this benefit
Water repairs cosmetics, repairs lyophilized powder including moisturizing and basic liquid is repaired in moisturizing, and described lyophilized powder is by pressing as follows
Component according to mass percentage forms: Semen Vitis viniferae oligosaccharide 0.1%～2%, hydrolyzes red algae oligosaccharide
0.5%～4%, small-molecular-weight hyaluronic acid 0.05%～1%, hydrolytic collagen 1%～5%, recombined human angle
Cell plastid somatomedin 0.00001%～0.001%, recombinant human epidermal growth factor 0.00001%～
0.001%, low molecular sodium heparin 0.01%～0.2%, stabilizer 1%～15% surplus is injection stage water；Institute
State basic liquid to be made up of following component based on gross mass percent: hyaluronic acid 0.01%～0.4%, methyl
Propylene glycol 0.5%～4%, Mel oligosaccharide 0.5%～5%, Anjidew NL50 0.5%～5%, soluble protein enzyme 0.5%～
5%, 1,2 hexanediol 0.3%～0.7%, Herba bromi japonici beta glucan 1.5%～6%, soybean isoflavone 1%～5%,
Surplus is deionized water or water for injection.
Need nonetheless remain for a kind of not only there is moisture-keeping function but also there is the cosmetic composition of restructuration.
Summary of the invention
The present invention provides a kind of cosmetic composition, and this cosmetic composition not only has moisture-keeping function (to skin
The effect on skin surface), i.e. there is the skin-friendly (alginate oligosaccharide) of excellence, the second weight can be provided to skin
The effect of skin；But also there is restructuration (effect to deep skin), epidermis deep layer can be increased
Epidermis hyaluronic acid contents；Activate the synthesis of tight junction protein 1, strengthen intercellular compact siro spinning technology；
Increase the synthesis of ceramide, improve lipid barrier.
The cosmetic composition of the present invention contains alginate oligosaccharide and red algae oligosaccharide.
In a specific embodiment, with total restatement of cosmetic composition, described cosmetic composition contains
0.5～the alginate oligosaccharide of 3% and 0.5～the red algae oligosaccharide of 3%.
In a specific embodiment, with total restatement of cosmetic composition, described cosmetic composition contains
0.5～the alginate oligosaccharide of 2% and 0.5～the red algae oligosaccharide of 2%.
In a specific embodiment, with total restatement of cosmetic composition, described cosmetic composition contains
0.5～the alginate oligosaccharide of 1.5% and 0.5～the red algae oligosaccharide of 1.5%.
In a specific embodiment, with total restatement of cosmetic composition, described cosmetic composition contains
The alginate oligosaccharide of 1.0% and the red algae oligosaccharide of 1.0%.
In a specific embodiment, alginate oligosaccharide and the weight ratio of red algae oligosaccharide in cosmetic composition
For 1:5 to 5:1.
In a specific embodiment, alginate oligosaccharide and the weight ratio of red algae oligosaccharide in cosmetic composition
For 1:3 to 3:1.
In a specific embodiment, alginate oligosaccharide and the weight ratio of red algae oligosaccharide in cosmetic composition
For 1:1.
In a specific embodiment, described alginate oligosaccharide has a structure that
In a specific embodiment, described red algae oligosaccharide has a structure that
A kind of method that present invention additionally comprises moistening effect improving cosmetic composition, described method include to
This cosmetic composition adds alginate oligosaccharide and red algae oligosaccharide.
In a specific embodiment, to add the cosmetics gross weight after alginate oligosaccharide and red algae oligosaccharide
Meter, is 0.5～3%, and the content of red algae oligosaccharide is 0.5～3%；Preferably, the containing of alginate oligosaccharide
Amount is 0.5～2%, and the content of red algae oligosaccharide is 0.5～2%；It is highly preferred that the containing of alginate oligosaccharide
Amount is 0.5～1.5%, and the content of red algae oligosaccharide is 0.5～1.5%.
In a specific embodiment, with 1:5 to 5:1, preferably 1:3 to 3:1, more preferably 1:1
Ratio alginate oligosaccharide and red algae oligosaccharide are added in described cosmetic composition.
In a specific embodiment, described cosmetic composition is astringent, emulsion, protective skin cream, face cleaning
Series products, facial treatment essence, eye-care, sunscreen product or powder adornment series products.
Accompanying drawing explanation
Fig. 1 shows that (% does not locates the changing value of skin moisture-keeping level relatively after desiccation stress processes 1 hour
The skin of reason).From left to right it is followed successively by blank group, alginate oligosaccharide: red algae oligosaccharide=1:3, Brown algae is low
Polysaccharide: red algae oligosaccharide=3:1, and alginate oligosaccharide: the changing value of red algae oligosaccharide=1:1.
Fig. 2 shows that (% does not locates the changing value of skin moisture-keeping level relatively after desiccation stress processes 16 hours
The skin of reason).From left to right it is followed successively by blank group, alginate oligosaccharide: red algae oligosaccharide=1:3, Brown algae is low
Polysaccharide: red algae oligosaccharide=3:1, and alginate oligosaccharide: the changing value of red algae oligosaccharide=1:1.
Fig. 3 shows that deep-sea of the present invention runs through the moisture-keeping efficacy of double algae elite.
Fig. 4 shows that deep-sea of the present invention runs through the instant of double algae elite and lasting moisture-keeping function compared with single algae.
It is blank group, the alginate oligosaccharide+red algae oligosaccharide of 1:1, the alginate oligosaccharide of 1% the most successively
Effect with the red algae oligosaccharide of 1%.
Detailed description of the invention
The present invention provides a kind of cosmetic composition, and this cosmetic composition contains alginate oligosaccharide and red algae is low
Polysaccharide.The present invention also provides for a kind of method of moistening effect improving cosmetic composition, the method include to
Cosmetic composition adds alginate oligosaccharide and red algae oligosaccharide.
Alginate oligosaccharide
Alginate oligosaccharide refers to extract from the oligosaccharide of Brown algae.
Alginate oligosaccharide for the present invention has effect immediately, can be combined with water immediately in horny layer；
Accumulative effect, i.e. every day use and epidermis moisturizing level can be made to significantly improve；And continue moistening effect,
Rebuild epidermis, there is long duration moisturizing effect.
It is applicable to the alginate oligosaccharide of the present invention and usually contains following structure:
Techniques known in the art means can be used to prepare alginate oligosaccharide from marine brown.Such as, can adopt
Prepare with enzymatic depolymerization.In the method, enzyme is the alginate lyase of Marine microorganism secretion.This enzyme can
Help to decompose the alginic acid (macromolecule Brown algae biological polyoses) in Brown algae (chelorella), finally degrade
Form little molecule alginate oligosaccharide.About the technology of the alginic acid utilized in alginate lyase depolymerization Brown algae,
Can be found in US 6207438 B1, herein its entire disclosure is included in by reference herein.Also
Commercially available alginate oligosaccharide can be used, such as, the alginate oligosaccharide product that codif company produces can be used.
It is applicable to the molecular weight of alginate oligosaccharide of the present invention generally in the range of 120～250kDa, such as
130～200kDa, 130～180kDa.In a specific embodiment, the molecular weight of alginate oligosaccharide
It is about 150kDa, such as, 150 ± 10kDa.
In cosmetic composition of the present invention, with total restatement of cosmetic composition, usually contain 0.5～3%
Alginate oligosaccharide, preferably comprises the alginate oligosaccharide of 0.5～2.0%, more preferably contain 0.5～1.5% brown
Algae oligosaccharide.In a specific embodiment, in cosmetic composition of the present invention containing 1.0% Brown algae low
Polysaccharide.
Red algae oligosaccharide
Red algae oligosaccharide refers to extract from the oligosaccharide of red algae.
Red algae oligosaccharide for the present invention is a kind of epidermis hyaluronic acid activator, it is possible to promote that epidermis is transparent
The synthesis of matter acid；The compact siro spinning technology of epidermal area can be strengthened, reduce TEWL；With can promote ceramide
Synthesis.Experimental data shows: red algae, from basal layer to cuticular layer, has extraordinary reconstruction to whole epidermis
Effect.
The anthelmintic fork red algae (Fucellaria being derived from marine site, Scandinavia, polar region, Northern Europe can be used
Lumbrilicalis, also name kylin algae, Flos Spatholirionis longifolii) extract the red algae oligosaccharide of the present invention.Through solving
The red algae powder acquisition red algae oligosaccharide that polysulfide is Esterification, it is rich in galactose and Anhydrogalactose..
Generally, after obtaining red algae, except water is dried, red algae powder is obtained.In anhydrous conditions, super facing is used
Boundary CO2Technology hydrolysis is through the red algae powder of Sulfation.Red algae oligosaccharide can be obtained after depolymerization.Can be
Red algae oligosaccharide is placed in the sea salt solution of 0.05% aquation again.The sea salt solution rehydration of employing 0.05% is red
Algae oligosaccharide powder, in sea salt solution rich in potassium element, can induced polymer formed double-spiral structure, with
This gives the characteristic of its hyaluronic acid.The red algae the molecular weight of oligosaccharide being consequently formed is typically larger than 100kDa, example
As in the range of 100～250kDa, such as 150～250kDa, 180～220kDa etc..A concrete reality
Executing in example, the molecular weight of red algae oligosaccharide is about 200kDa, such as 200 ± 10kDa.Meantime, it is preferable that
Red algae oligosaccharide comprises following structure:
The supercritical CO described in such as WO 01/28649 can be used2The red algae that technology extracts the present invention is oligomeric
Sugar, includes in the full content of this article herein herein by reference.Or, codif company can be used
The red algae oligosaccharide product produced.
In cosmetic composition of the present invention, with total restatement of cosmetic composition, usually contain 0.5～3%
Red algae oligosaccharide, preferably comprises the red algae oligosaccharide of 0.5～2.0%, more preferably contain 0.5～1.5% red
Algae oligosaccharide.In a specific embodiment, in cosmetic composition of the present invention containing 1.0% red algae low
Polysaccharide.
Additive
In addition to constituting the deionized water of most of weight of cosmetic composition of the present invention, the cosmetics of the present invention
Compositions can also comprise the multiple additive used at cosmetic field.CTFA Cosmetic Ingredient Dictionary
(CTFA Cosmetic Ingredient Handbook) describes a large amount of those skilled in the art's routine to be made
Nonlimiting cosmetic composition, they be suitable in the cosmetic composition of the present invention use.This kind of one-tenth
The example of classifying type includes but not limited to: preservative, grinding agent, emulsifying agent, emollient, absorbent, glue
Solidifying agent, antifoaming agent, buffer agent, coloring agent, filmogen, pH adjusting agent, wetting agent, skin conditioning agent,
Thickening agent, aromatic and pigment.
Such as, this kind of additive includes:
(1) solid and Wax, as oil, lanoline, ceresine, microwax, Brazil wax,
C10-C30 fatty acid and C10-C30 alcohols material etc.；
(2) oily substance, such as olive oil, Jojoba oil, Oleum Ricini, sunflower oil, hazelnut oil, breast wood
Fruit oil Flos Carthami oil etc.；
(3) viscosity modifier/stabilizer, such as guar gum, xanthan gum, carrageenin, hydroxy ethyl fiber
Element, fungi plant glue, carbomer glue, polyacrylate and acrylate-C10-C30 alkyl acrylate are altogether
Polymers etc.；
(4) hydrophilic wetting agent, such as glycerol, propylene glycol, butanediol, sodium lactate, Anjidew NL50 etc.；
(5) emollient, such as isononyl isononanoate, dicaprylyl carbonate, spermol ethylhexoate, glycerol
Three (thylhexoic acid) ester, dicaprylyl ether, myristyl myristate, the caprate of C10-C30, contain
The triglyceride of the C10-C30 of octanoic acid and/or capric acid and the glyceride etc. of C10-C30；
(6) co-emulsifier, as hexadecanol, octadecanol, 16 octadecanols, tristerin,
Stearic acid, glycol glycerin ester, glycerol distearate etc.；
(7) emulsifying agent, including nonionic surfactant and anion surfactant, described the moon
Ionic surface active agent such as contain the salt of 2-Lauroyloxypropionic acid, the salt of Caproyllactic acid, the salt of cocos nucifera oil acyl lactic acid,
The salt of stearoyl lactylates, the salt of olive oil spermaceti alcohol ester, the salt of olive oil Sorbitol or glyceryl oleate lemon
The salt etc. of lemon acid esters, the typical cation of these salt includes sodium ion, potassium ion, ammonium ion, calcium ion
With magnesium ion etc.；Described non-ionic surfactants such as polyoxyethylene carboxylate, sorbitan ester,
Sucrose ester, alkyl polyglucoside class, glycerol citrate and polyglycereol lipid etc.；
(8) silicone oil material；
(9) coloring agent, auxiliary joins thing and inorganic dyestuff etc. as inorganic；
(10) preservative, such as phenoxyethanol and parabens etc.；
(11) pH adjusting agent, such as sodium hydroxide, potassium hydroxide and triethanolamine etc..
(12) aromatic, such as all kinds of quintessence oils and compound essence；Etc..
The whole structure produced by cosmetic composition of the present invention based on hope, the cosmetic combinations of the present invention
Thing can also use other cosmetic active ingredient, such as: Anti-acne actives (such as: salicylic acid or
Benzoyl peroxide), antiwrinkle active thing (such as: retinoid or β-hydroxy acid), antioxidant (such as:
Ascorbic acid and derivant thereof, or Folium Camelliae sinensis oligosaccharide), chelating agen (such as: EDETATE SODIUM), antiinflammatory (example
Such as corticosteroid), anoretic (such as: caffeine), skin lightening agent (such as: Fructus Mori oligosaccharide or
Kojic acid), or sunscreen (such as: the commercially available product of entitled PARSOL).
The general group being prepared the present invention by the conventional method preparing cosmetic composition known in the art
Compound.This type of method relates generally to blending constituent in one or more steps, becomes relatively uniform state,
Wherein it is with or without heating, cools down, use vacuum etc..Compositions can be the form of any routine, such as
Gel, emulsifiable paste, lotion, or wash-off type product.
The amount of additive is also the conventional amount used of this area.
Cosmetic composition
As it was previously stated, cosmetic composition of the present invention contains alginate oligosaccharide and red algae oligosaccharide.With cosmetics
Total restatement of compositions, usually contains the alginate oligosaccharide of 0.5～3%, preferably comprise 0.5～2.0% brown
Algae oligosaccharide, more preferably contains the alginate oligosaccharide of 0.5～1.5%, and 0.5～the red algae oligosaccharide of 3%,
Preferably comprise the red algae oligosaccharide of 0.5～2.0%, more preferably contain the red algae oligosaccharide of 0.5～1.5%.
Generally, in cosmetic composition, the weight ratio of alginate oligosaccharide and red algae oligosaccharide is at 1:5 to 5:1
Within the scope of, preferably 1:3 to 3:1, more preferably 1:1.
Such as, cosmetic composition contains 0.5% respectively, 0.6%, 0.7%, 0.8%, 0.9%,
1.0%, the alginate oligosaccharide of the equal proportion of 1.1% or 1.2% and red algae oligosaccharide.
Therefore, in a preferred embodiment of the invention, cosmetic composition contains the Brown algae of about 1.0%
Oligosaccharide and the red algae oligosaccharide of about 1.0%.
As it was previously stated, techniques known in the art means can be used to extract for the present invention from Brown algae and red algae
The alginate oligosaccharide of cosmetics and red algae oligosaccharide.Or it is used as commercially available product to prepare the present invention's
Cosmetic composition.The example of commercially available prod includes that the PHEONOV deep-sea that codif company produces runs through double algae essence
China.
The example of cosmetic composition of the present invention includes astringent, emulsion, protective skin cream, face cleaning series products, protects
Skin elite, eye-care, sunscreen product and powder adornment series products etc..
In a specific embodiment, cosmetic composition of the present invention is except oligomeric containing alginate oligosaccharide and red algae
Sugar is outer and water, also can contain hydrophilic wetting agent (such as glycerol and butanediol), viscosity modifier (such as card
Ripple nurse), preservative (such as euxyl K350), pH adjusting agent (such as triethanolamine), aromatic and chelating
Agent (such as edta salt, such as EDETATE SODIUM).Generally, with total restatement of cosmetic composition, hydrophilic is protected
The content of humectant is 2～20%, and the content of viscosity modifier is 0.05～0.5%, the content of preservative for for
0.1～0.5%, the content of pH adjusting agent is 0.05～0.5%, and the content of aromatic is 0.01～0.5%,
The content of chelating agen is 0.01～0.05%.
In a specific embodiment, the hydrophilic wetting agent in the cosmetic composition of the present invention be glycerol,
And butanediol, with total restatement of cosmetic composition, the content of glycerol is 2～10%, the content of butanediol
It is 2～8%.
Different cosmetic compositions can be containing different additives.Such as, astringent is except containing the present invention's
Alginate oligosaccharide and red algae oligosaccharide be outer and water, also can contain hydrophilic wetting agent (such as glycerol, butanediol),
Viscosity modifier (such as carbomer), preservative (such as euxyl K350), pH adjusting agent (such as triethanolamine),
Aromatic, oily substance (such as PEG-60 castor oil hydrogenated) and chelating agen (such as EDETATE SODIUM)；Emulsion is also
Can contain hydrophilic wetting agent (such as glycerol and butanediol), emollient (as caprylic/capric triglyceride,
Isononyl isononanoate and cetearyl alcohol), silicone oil, nonionic surfactant is (such as cetearyl
Glucoside), viscosity modifier (such as carbomer), preservative, pH adjusting agent (such as triethanolamine), virtue
Pastil, chelating agen (such as EDETATE SODIUM)；Protective skin cream also can contain hydrophilic wetting agent (such as glycerol, fourth two
Alcohol), emollient is (such as dicaprylyl carbonate, cetearyl alcohol ethylhexoate, glycerol three (thylhexoic acid)
Ester, cetearyl alcohol), silicone oil, anion surfactant (such as glyceryl stearate citrate), viscous
Degree regulator (such as carbomer), preservative, pH adjusting agent (such as triethanolamine), aromatic and chelating agen
(such as EDETATE SODIUM).The consumption of these additives is the conventional amount used of this area.
The method that this area can be used conventional prepares cosmetics of the present invention, such as by being mixed by each composition simply
Close uniformly.Or, as shown in the embodiment of the present application, for different cosmetic compositions, first will not
Same component is mixed into different mixture at different conditions, the most again these mixture is blended in one
Rise.These are all within the technical scope that those skilled in the art are grasped.
It should be understood that the total amount percentage ratio sum of all components in compositions should be equal to 100%.
The method improving the moistening effect of cosmetic composition
Alginate oligosaccharide and red algae oligosaccharide can be added in existing cosmetic composition, thus improve this change
The moistening effect of cosmetic compositions.Existing cosmetic composition includes but not limited to astringent, emulsion, protects
Skin frost, face cleaning series products, facial treatment essence, eye-care, sunscreen product and powder adornment series products etc., its composition
Include but not limited to previously described various composition.
Generally, with the addition of total restatement of the cosmetic composition after alginate oligosaccharide and alginate oligosaccharide, brown
The content of algae oligosaccharide is 0.5～3.0%, preferably 0.5～2.0%, more preferably 0.5～1.5%；Red algae is low
The content of polysaccharide is 0.5～3.0%, preferably 0.5～2.0%, more preferably 0.5～1.5%.Oligomeric with two kinds
The adding proportion meter of sugar, the adding proportion of alginate oligosaccharide and red algae oligosaccharide is usually 1:5～5:1, excellent
Elect 1:3～3:1 as, more preferably 1:1.Such as, in a specific embodiment, Brown algae is added oligomeric
After sugar and red algae oligosaccharide, cosmetic composition is about 0.5% containing respective content, 0.6%, 0.7%,
0.8%, the alginate oligosaccharide of the equal proportion of 0.9%, 1.0%, 1.1% or 1.2% and red algae oligosaccharide.
Compared with the contrast cosmetic composition being not added with alginate oligosaccharide and red algae oligosaccharide, same test bar
Under part, the moistening effect of cosmetic composition of the present invention to improve more than 10%, for example, at least 20%, preferably
At least 30%, at least 40%, at least 50% etc..
Alginate oligosaccharide and red algae oligosaccharide are added in cosmetic composition by the method that can use routine.
The present invention will be described in the way of specific embodiment below.Should be understood that these embodiments are only to illustrate
Property, rather than limit the scope of the invention.In embodiment, alginate oligosaccharide used and red algae oligosaccharide obtain
The product produced from codif company, remaining composition all can obtain from commercially available approach.
Embodiment: the preparation of cosmetic composition of the present invention
The formula of according to the form below 1-3 prepares astringent, emulsion and protective skin cream.
Table 1: astringent formula
| The number of phases | Composition | Content (percentage by weight) |
| A | Water | Add to 100% |
| A | Glycerol | 5% |
| A | Butanediol | 5% |
| A | Carbopol | 0.1% |
| A | EDETATE SODIUM | 0.02% |
| B | Triethanolamine | 0.1% |
| C | Alginate oligosaccharide | 0.5% |
| C | Red algae oligosaccharide | 1% |
| C | Essence | 0.05% |
| C | PEG-60 castor oil hydrogenated | 0.2% |
| C | Preservative euxyl K350 | 0.3% |
Preparation method:
(1) A phase material mixing dispersing and dissolving is uniform, it is heated to 70 DEG C；
(2) stirring is cooled to when 50 DEG C add triethanolamine, and stirring neutralizes；
(3) stirring is cooled to when 45 DEG C add C phase material, stirs.
Table 2: emulsion formulations
| The number of phases | Composition | Content (percentage by weight) |
| A | Water | Add to 100% |
| A | Glycerol | 6% |
| A | Butanediol | 3% |
| A | EDETATE SODIUM | 0.02% |
| A | Carbomer981 | 0.1% |
| B | Caprylic/capric triglyceride | 5% |
| B | Isononyl isononanoate | 3% |
| B | Silicone oil | 1% |
| B | Cetearyl alcohol | 0.5% |
| B | Cetearyl glucoside | 1.5% |
| C | Triethanolamine | 0.1% |
| D | euxyl K350 | 0.3% |
| D | Essence | 0.1% |
| D | Alginate oligosaccharide | 2% |
| D | Red algae oligosaccharide | 1% |
Preparation method:
(1) A phase material mixing dispersing and dissolving is uniform, it is heated to 75 DEG C；
(2) B phase material is mixed, be heated to 75 DEG C；
(3) B phase material addition A phase is carried out emulsifying, and use homogenizer homogenizing 3 minutes；
(4) add triethanolamine after emulsifying terminates, use homogenizer homogenizing 1 minute；
(5) stirring is cooled to when 45 DEG C add D phase material, uses homogenizer homogenizing 1 minute.
Table 3: protective skin cream
| The number of phases | Composition | Content (percentage by weight) |
| A | Water | Add to 100% |
| A | Glycerol | 6% |
| A | Butanediol | 4% |
| A | Carbopol | 0.2% |
| A | EDETATE SODIUM | 0.02% |
| A | Dicaprylyl carbonate | 4% |
| B | Cetearyl alcohol ethylhexoate | 3% |
| B | Glycerol three (thylhexoic acid) ester | 2% |
| B | Silicone oil | 1% |
| B | Cetearyl alcohol | 2% |
| B | Glyceryl stearate citrate | 2.5% |
| C | Triethanolamine | 0.2% |
| D | Alginate oligosaccharide | 1% |
| D | Red algae oligosaccharide | 1% |
| D | euxyl K350 | 0.3% |
| D | Essence | 0.1% |
Preparation method:
(1) A phase material mixing dispersing and dissolving is uniform, it is heated to 75 DEG C；
(2) B phase material is mixed, be heated to 75 DEG C；
(3) B phase material addition A phase is carried out emulsifying, and use homogenizer homogenizing 3 minutes；
(4) add triethanolamine after emulsifying terminates, use homogenizer homogenizing 1 minute, and stir cooling；
(5) stirring is cooled to when 45 DEG C add D phase material, uses homogenizer homogenizing 1 minute.
Test case
This test case uses the protective skin cream (percentage by weight of two kinds of algae oligosaccharide shown in table 3 in embodiment
Sum is 2%) test, only by the ratio between alginate oligosaccharide therein and red algae oligosaccharide
Change 1:3,1:1 and 3:1 successively into.
1, single algae test data of different proportion
Experimental technique: implant outer to skin uses salt crystal to carry out the serious processed of 2h, then office in advance
Portion's skin uses has the protective skin cream of formula shown in table 3 (only by low to alginate oligosaccharide therein and red algae
Ratio between polysaccharide changes 1:3,1:1 and 3:1 successively into), use corneometry technical testing skin
Skin moisturizing level, test alginate oligosaccharide and effect of red algae oligosaccharide ratio (1:3,1:1 and 3:1).
After desiccation stress processes 1 hour, the changing value (the most untreated skin of %) of skin moisture-keeping level
See Fig. 1.After desiccation stress processes 16 hours, changing value (the most untreated skin of % of skin moisture-keeping level
Skin) see Fig. 2.
The result of Fig. 1 and 2 shows, after desiccation stress processes 1 hour and 16 hours, uses containing 2% different
The deep-sea of single algae ratio runs through double algae elite all can be effectively improved the hydration levels of skin, and protects during ratio 1:1
Wet effect is the most obvious.
Test case 2: cosmetic composition moisture-keeping efficacy of the present invention
Experimental technique: implant outer to skin uses salt crystal to carry out the serious processed of 2h, then office in advance
Portion's skin uses the protective skin cream (ratio between alginate oligosaccharide and red algae oligosaccharide with formula shown in table 3
For 1:1), use corneometry technical testing skin moisture-keeping level.
Result shows in figure 3.Result shows, although through serious desiccation stress, deep-sea of the present invention is moistened
The most double algae elite still can make skin the most independently be hydrated at once, after using 2% deep-sea to run through double algae elite, and 1
Hour inner skin moisturizing level improves 75%.
Test case 3: compared with single algae, tests the instant of cosmetic composition of the present invention and makees with lasting moisturizing
With
The above experimental technique of same employing, the moisturizing level of skin after test 16h.No. 1 is blank group,
No. 2 use the protective skin cream (ratio between alginate oligosaccharide and red algae oligosaccharide is 1:1) of formula shown in table 3,
No. 3 use 1% alginate oligosaccharide, and No. 4 use 1% red algae oligosaccharide oligosaccharide.
Result shows in the diagram.In Fig. 4, it is the moistening effect figure of No. 1-4 the most respectively.By Fig. 4
It can be seen that after desiccation stress 16 hours, deep-sea of the present invention runs through double algae elite (No. 2) than single algae
Moisture-keeping function more potent, there is synergy.
Claims (10)
1. a cosmetic composition, it is characterised in that described cosmetic composition contains alginate oligosaccharide
With red algae oligosaccharide.
2. cosmetic composition as claimed in claim 1, it is characterised in that with cosmetic composition
Total restatement, described cosmetic composition contain 0.5～the alginate oligosaccharide of 3% and 0.5～3% red algae low
Polysaccharide.
3. cosmetic composition as claimed in claim 1 or 2, it is characterised in that described cosmetics group
In compound, alginate oligosaccharide is 1:5 to 5:1 with the weight ratio of red algae oligosaccharide.
4. the cosmetic composition as according to any one of claim 1-3, it is characterised in that
(1) with total restatement of cosmetic composition, described cosmetic composition contains the Brown algae of 0.5～2%
Oligosaccharide and 0.5～the red algae oligosaccharide of 2%, preferably comprise 0.5～the alginate oligosaccharide of 1.5% and 0.5～
The red algae oligosaccharide of 1.5%, more preferably contains the alginate oligosaccharide of 1.0% and the red algae oligosaccharide of 1.0%；
Or
(2), in described cosmetic composition, alginate oligosaccharide is that 1:3 arrives with the weight ratio of red algae oligosaccharide
3:1, preferably 1:1.
5. the cosmetic composition as according to any one of claim 1-4, it is characterised in that described brown
Algae oligosaccharide obtains by using alginate lyase to decompose the alginic acid of Brown algae, and described red algae oligosaccharide leads to
Cross employing supercritical CO2Technology hydrolysis obtains through the red algae powder of Sulfation.
6. the cosmetic composition as according to any one of claim 1-5, it is characterised in that described brown
The molecular weight of algae oligosaccharide is 120～250kDa, and has a structure that
The molecular weight of described red algae oligosaccharide is 100～250kDa, and has a structure that
7. the cosmetic composition as according to any one of claim 1-6, it is characterised in that describedization
Cosmetic compositions is possibly together with one or more in following additive: preservative, grinding agent, emulsifying
Agent, absorbent, gellant, antifoaming agent, buffer agent, coloring agent, filmogen, pH adjusting agent, moistening
Agent, thickening agent, aromatic and pigment.
8. cosmetic composition as claimed in claim 1, it is characterised in that described cosmetic composition
For astringent, emulsion, protective skin cream, face cleaning series products, facial treatment essence, eye-care, sun-proof or powder adornment class
Product.
9. the method improving the moistening effect of cosmetic composition, described method includes to these cosmetics
Compositions adds alginate oligosaccharide and red algae oligosaccharide.
10. method as claimed in claim 9, it is characterised in that described method includes with next or many
Individual feature:
(1) to add the total restatement of cosmetics after alginate oligosaccharide and red algae oligosaccharide, it is 0.5～3%,
The content of red algae oligosaccharide is 0.5～3%；Preferably, the content of alginate oligosaccharide is 0.5～2%, red
The content of algae oligosaccharide is 0.5～2%；It is highly preferred that the content of alginate oligosaccharide is 0.5～1.5%,
The content of red algae oligosaccharide is 0.5～1.5%.
(2) with 1:5 to 5:1, the ratio of preferably 1:3 to 3:1, more preferably 1:1 is low by Brown algae
Polysaccharide and red algae oligosaccharide are added in described cosmetic composition；
(3) described cosmetic composition is astringent, emulsion, protective skin cream, face cleaning series products, skin protection essence
China, eye-care, sunscreen product or powder adornment series products；
(4) described alginate oligosaccharide obtains by using alginate lyase to decompose the alginic acid of Brown algae,
Described red algae oligosaccharide is by using supercritical CO2Technology hydrolysis obtains through the red algae powder of Sulfation；
(5) molecular weight of described alginate oligosaccharide is 120～250kDa, and has a structure that
The molecular weight of described red algae oligosaccharide is 100～250kDa, and has a structure that
(6) described cosmetic composition contains one or more in following additive: preservative,
Grinding agent, emulsifying agent, absorbent, gellant, antifoaming agent, buffer agent, coloring agent, filmogen, pH
Regulator, wetting agent, thickening agent, aromatic and pigment.
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| WO2020054972A1 (en) * | 2018-09-14 | 2020-03-19 | (주)더원코스메틱 | Skin whitening, anti-wrinkle and antioxidant functional cosmetic composition containing mixed extract of gloiopeltis tenax, palmaria palmata and himanthalia elongata as active ingredient, and preparation method therefor |
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