CN110251423A - A kind of skin care compositions and preparation method thereof - Google Patents
A kind of skin care compositions and preparation method thereof Download PDFInfo
- Publication number
- CN110251423A CN110251423A CN201910663116.6A CN201910663116A CN110251423A CN 110251423 A CN110251423 A CN 110251423A CN 201910663116 A CN201910663116 A CN 201910663116A CN 110251423 A CN110251423 A CN 110251423A
- Authority
- CN
- China
- Prior art keywords
- skin care
- care compositions
- parts
- mass fraction
- sodium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/81—Preparation or application process involves irradiation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
The invention belongs to technical field of skin care, more particularly to a kind of skin care compositions and preparation method thereof, the composition includes following component according to the mass fraction: 2-20 parts of polyol humectant, 0.05-0.4 parts of Sodium Hyaluronate, 0-0.2 parts of xanthan gum, 0.5-2.5 parts of trehalose, 0-0.6 parts of antioxidant.Skin care compositions prepared by the present invention is sterile, preservative free, has stronger moisturizing, moisturizing and antioxidation, and preparation method is simple, can be used in the skin care item such as moisturizing spraying, moisture retention water, essence lotion, lotion.
Description
Technical field
The invention belongs to technical field of skin care, and in particular to a kind of skin care compositions and preparation method thereof.
Background technique
Dry skin is one of skin problem very common in daily life, can be alleviated by moisturizing, moisturizing.On the market
Existing moisturizer includes spraying moisture retention water, moisturizing, moisturizing cream, moisturizer etc..
Moisturizer is often haved the function that sterilization by addition preservative, extended the shelf life.Patent
It is spraying that CN201610816339.8 provides a kind of skin care that can adjust skin water and oil balance, is added to methyl hydroxybenzoate and benzene oxygen second
The preservatives such as alcohol.But preservative can cause different degrees of stimulation and injury to human skin, give while killing microorganism
Skin safe brings risk.
In addition to addition preservative suppresses growth of microorganism, there are also wet for the method for the killing microorganism being often used in the prior art
Heat sterilization, irradiation sterilization etc..Usual moist heat sterilization needs temperature to be greater than 115 DEG C, and the duration is long, and general Cosmetic Manufacture is set
It is standby not to be able to satisfy；And for irradiation sterilization, after being irradiated discoloration, Odor stimulation, acid easily occur for many ingredients in skin care item
The variations such as basicity is extreme and Material property changes.
Patent CN201810708974.3 discloses a kind of neutral preservative free exfoliating composition, including film forming copolymerization
Object, pH adjusting agent and carbomer are not added with preservative, but are added to the pentanediol and ethyl alcohol of high level, both ingredients pair
Sensitive skin has higher irritation；In addition do not sterilize effectively means in product preparation process, only extremely by heating Material
80-85 DEG C, heat preservation 10min is unable to reach reliable sterilization functions.
Aiming at the problems existing in the prior art, need to research and develop it is a kind of be not attached to preservative injury, safe moisturizing produces
Product.
Summary of the invention
In order to solve the problems in the existing technology, the present invention proposes a kind of skin care compositions and preparation method thereof.
A kind of skin care compositions, including following component according to the mass fraction: 2-20 parts of polyol humectant, hyaluronic acid
0.05-0.4 parts of sodium, 0-0.2 parts of xanthan gum, 0.5-2.5 parts of trehalose, 0-0.6 parts of antioxidant, surplus is water.
Further, the polyol humectant is selected from one of glycerol, polyethylene glycol, propylene glycol, butanediol or more
Kind.
Further, mass fraction of the glycerol in the skin care compositions is 2-5 parts, and the polyethylene glycol is in institute
Stating the mass fraction in skin care compositions is 0-5 parts, and mass fraction of the propylene glycol in the skin care compositions is 0-5
Part, mass fraction of the butanediol in the skin care compositions is 0-5 parts.
Further, the antioxidant is selected from one of sodium sulfite, sodium hydrogensulfite, tea polyphenols or a variety of.
Further, mass fraction of the sodium sulfite in the skin care compositions is 0-0.2 parts, the sulfurous acid
Mass fraction of the hydrogen sodium in the skin care compositions is 0-0.2 parts, quality of the tea polyphenols in the skin care compositions
Number is 0-0.2 parts.
A kind of preparation method of skin care compositions, includes the following steps:
(1) polyol humectant, Sodium Hyaluronate, xanthan gum, antioxidant are added in reaction kettle and are stirred evenly, added water, stir
It mixes and is heated to 70 DEG C；
(2) after polyol humectant, Sodium Hyaluronate, xanthan gum, antioxidant all dissolution, trehalose, stirring drop is added
Temperature；
(3)≤40 DEG C are down to temperature, discharging is filling；
(4) after the completion of filling, 8-25Kgy Co60Irradiation sterilization is to get the skin care compositions.
Further, the preparation method of the skin care compositions, the sterilizing methods in step (4) can also be electron beam
Irradiation sterilization, irradiation dose 8-25Kgy.
Further, the invention also includes the skin care compositions is sprayed, in moisture retention water, essence lotion, lotion in moisturizing
Using.
Compared to the prior art, the beneficial effect that the present invention is played is:
Glycerol, polyethylene glycol, propylene glycol, butanediol are polyol humectant, and property is stablized, is dissolved in water, is preferable moisturizing
Agent.Sodium Hyaluronate has good moistening effect, may act on skin surface, forms one layer of protective film, make skin wet
It is smooth, it may additionally facilitate proliferation, the differentiation of epidermal cell, repair skin injury.Xanthan gum is that a kind of fermented by Xanthomonas campestris produces
Raw Extra-cellular acidic heteroglycan, meeting water dispersion, emulsifying is stable hydrophily thick gel, can be used as thickener and stabilization
Agent.Trehalose is a kind of safe natural carbohydrate, under the severe environmental conditions such as high temperature, high and cold, hyperosmosis and dry dehydration,
Protective film can be formed in cell surface, the protein molecule invariance inactivation in effective protection Skin Cell stops simultaneously
External contaminants intrusion.Sodium sulfite is inorganic compound, water-soluble and glycerol, and aqueous solution is in alkalescent, food-grade sulfurous
Sour sodium can be used as antioxidant.Sodium hydrogensulfite is soluble easily in water, is slightly soluble in alcohol, and the sodium hydrogensulfite of food-grade can be used as anti-oxidant
Agent.Tea polyphenols are a kind of polyhydroxy phenol type organic matter being present in tealeaves, and molecular weight is relatively small, Transdermal absorption ability compared with
By force, activity stabilized, there is stronger antioxidant activity, be a kind of natural antioxidant.Radiogen Co60The γ radiated is penetrated
Line can change the internal structure of microorganism, bacterium, such as destroy microorganism, bacterium inhereditary material, thus play inhibition or
The effect of sterilization, Co60The penetrability of irradiation sterilization is stronger, and dosage is lower, not will increase the temperature of product in sterilization process,
Risk, but Co are remained without irradiation60Irradiation sterilization easily causes the property of moieties to change, occur product discoloration, pH it is extreme
Deng variation, therefore using Co60When irradiation sterilization, it must consider product composition, avoid the above problem occur because of irradiation sterilization.Electricity
Beamlet irradiation sterilization refers to the high electron beam irradiation generated using electron accelerator, to kill a kind of sterilizing of bacterium, virus
Method, irradiation processing period, absorbed dose are uniform, have the characteristics that room temperature, environmental protection, nontoxic, noresidue, low consumption, safety
Reliably.
Skin care compositions of the present invention does not add preservative, kills microorganism, bacterium using irradiation sterilization method, reaches nothing
Bacterium, preservative free purpose, and the skin care compositions be irradiated sterilizing after without discoloration, denaturation etc. influence, property stablize；This hair
The skin care compositions of bright preparation is sterile, preservative free, has stronger moisturizing, moisturizing and antioxidation, and Product Safety is high
And preparation method is simple, can be used in the skin care item such as moisturizing spraying, moisture retention water, essence lotion, lotion.
Specific embodiment
Below in conjunction with specific embodiment, technical solution of the present invention is described in detail.
Embodiment 1
The present embodiment provides a kind of skin care compositions, including following component according to the mass fraction: 5 parts of glycerol, polyethylene glycol 1
Part, 0.2 part of Sodium Hyaluronate, 1 part of trehalose, 0.01 part of sodium sulfite, 0.01 part of sodium hydrogensulfite, surplus are water.
A method of the skin care compositions is prepared, is included the following steps:
(1) glycerol, polyethylene glycol, Sodium Hyaluronate, sodium sulfite, sodium hydrogensulfite are added in reaction kettle, stir evenly, adds
Water is stirred and heated to 70 DEG C；
(2) after glycerol, polyethylene glycol, Sodium Hyaluronate, sodium sulfite, sodium hydrogensulfite all dissolution, trehalose is added, stirs
Mix cooling；
(3) 35 DEG C are down to temperature, discharging is filling；
(4) after the completion of filling, 10Kgy Co60Irradiation sterilization is to get the skin care compositions.
Embodiment 2
The present embodiment provides a kind of skin care compositions, including following component according to the mass fraction: 2 parts of glycerol, polyethylene glycol 5
Part, 1 part of propylene glycol, 1 part of butanediol, 0.4 part of Sodium Hyaluronate, 0.2 part of xanthan gum, 2.5 parts of trehalose, sodium sulfite 0.05
Part, 0.2 part of sodium hydrogensulfite, 0.1 part of tea polyphenols, surplus is water.
A method of the skin care compositions is prepared, is included the following steps:
(1) glycerol, polyethylene glycol, Sodium Hyaluronate, xanthan gum, sodium hydrogensulfite, tea polyphenols are added in reaction kettle, stirring is equal
It is even, add water, is stirred and heated to 70 DEG C；
(2) it is all dissolved to glycerol, polyethylene glycol, Sodium Hyaluronate, xanthan gum, sodium sulfite, sodium hydrogensulfite, tea polyphenols
Afterwards, trehalose, stirring cooling is added；
(3) 40 DEG C are down to temperature, discharging is filling；
(4) after the completion of filling, 8Kgy Co60Irradiation sterilization is to get the skin care compositions.
Embodiment 3
The present embodiment provides a kind of skin care compositions, including following component according to the mass fraction: 3 parts of glycerol, 5 parts of propylene glycol,
5 parts of butanediol, 0.05 part of Sodium Hyaluronate, 0.1 part of xanthan gum, 0.5 part of trehalose, 0.2 part of sodium sulfite, sodium hydrogensulfite
0.05 part, 0.2 part of tea polyphenols, surplus is water.
A method of the skin care compositions is prepared, is included the following steps:
(1) glycerol, propylene glycol, butanediol, Sodium Hyaluronate, xanthan gum, sodium sulfite, sodium hydrogensulfite, tea polyphenols are added
It in reaction kettle, stirs evenly, adds water, be stirred and heated to 70 DEG C；
(2) whole to glycerol, propylene glycol, butanediol, Sodium Hyaluronate, xanthan gum, sodium sulfite, sodium hydrogensulfite, tea polyphenols
After dissolution, trehalose, stirring cooling is added；
(3) 35 DEG C are down to temperature, discharging is filling；
(4) after the completion of filling, 25Kgy Co60Irradiation sterilization is to get the skin care compositions.
Embodiment 4
The present embodiment provides a kind of skin care compositions, including following component according to the mass fraction: 3 parts of glycerol, polyethylene glycol 3
Part, 0.05 part of Sodium Hyaluronate, 0.1 part of xanthan gum, 0.5 part of trehalose, 0.1 part of sodium sulfite, 0.1 part of sodium hydrogensulfite, tea
0.05 part of polyphenol, surplus is water.
A method of the skin care compositions is prepared, is included the following steps:
(1) reaction kettle is added in glycerol, polyethylene glycol, Sodium Hyaluronate, xanthan gum, sodium sulfite, sodium hydrogensulfite, tea polyphenols
In, it stirs evenly, adds water, be stirred and heated to 70 DEG C；
(2) it is all dissolved to glycerol, polyethylene glycol, Sodium Hyaluronate, xanthan gum, sodium sulfite, sodium hydrogensulfite, tea polyphenols
Afterwards, trehalose, stirring cooling is added；
(3) 35 DEG C are down to temperature, discharging is filling；
(4) after the completion of filling, 8Kgy electron beam irradiation sterilization is to get the skin care compositions.
Embodiment 5
The present embodiment provides a kind of skin care compositions, including following component according to the mass fraction: 3 parts of glycerol, polyethylene glycol 2
Part, 0.2 part of Sodium Hyaluronate, 0.5 part of trehalose, surplus is water.
A method of the skin care compositions is prepared, is included the following steps:
(1) glycerol, polyethylene glycol, Sodium Hyaluronate are added in reaction kettle, stir evenly, add water, is stirred and heated to 70 DEG C；
(2) after glycerol, polyethylene glycol, Sodium Hyaluronate all dissolution, trehalose, stirring cooling is added；
(3) 38 DEG C are down to temperature, discharging is filling；
(4) after the completion of filling, 25Kgy electron beam irradiation sterilization is to get the skin care compositions.
The irritation and safety for the skin care compositions that testing example 1 is prepared to embodiment 5, obtain following result.
(1) irritation test
Test products: skin care compositions prepared by embodiment 1 to embodiment 5.
Comparative example are as follows: the methyl hydroxybenzoate and mass fraction that addition mass fraction is 0.05 part in embodiment 1 are 0.4 part
Phenoxyethanol, filling completion, does not do radiation treatment.Remaining component and step are identical.
Product irritation test is carried out using chick chorioallantoic membrane (HET-CAM) method, test method refers to Zheng Saihua, Wu
It is published within more 2013 " body of the chick chorioallantoic membrane test for cosmetics of " household chemicals science " the 9th phase of volume 36
The evaluation of outer eye irritation " in reaction time method.
Test result such as table 1.
1 irritation test result of table
| Test product | Comparative example 1 | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 |
| HET-CAM integral | 7 | 0 | 0.1 | 0.3 | 0.1 | 0 |
| Irritation evaluation | Moderate stimulation | It is non-stimulated | It is non-stimulated | It is non-stimulated | It is non-stimulated | It is non-stimulated |
(2) moisture retention is tested
20-40 years old 120 people of volunteer is chosen, every 20 people is divided into one group, and 1 control group and 5 test groups is arranged, and test group is compiled
Number are as follows: 1 group, 2 groups, 3 groups, 4 groups, 5 groups.After face cleaning, volunteer's face moisture content is tested, is averaged according to grouping；According to
Packet numbering, control group are not processed, and the corresponding skin care compositions prepared using embodiment 1 to embodiment 5 of test group is smeared complete
Face absorbs naturally.After smearing when 10min, 30min, 60min, volunteer's face moisture content is tested, is averaged according to grouping
Value.Test result is shown in Table 2.
2 moisture retention test result of table
| Before smearing | 10min | 30min | 60min | |
| Control group | 26.7 | 26.2 | 25.8 | 25.0 |
| 1 group | 25.8 | 49.6 | 47.7 | 45.8 |
| 2 groups | 25.4 | 49.0 | 47.3 | 45.2 |
| 3 groups | 24.8 | 48.6 | 46.7 | 44.8 |
| 4 groups | 25.7 | 49.1 | 47.5 | 45.4 |
| 5 groups | 26.2 | 49.2 | 47.3 | 45.0 |
Moisture retention experiment results proved has more significant according to skin care compositions prepared by the method for embodiment 1 to embodiment 5
Moisture-retaining capacity.
(3) safety testing
After the test, inquiry and observation test group volunteer face situation carry out Product Safety evaluation, obtain table moisture retention
3。
3 safety testing result of table
| Test product | 1 group | 2 groups | 3 groups | 4 groups | 5 groups |
| The symptoms (people) such as irritating, fever | 0 | 0 | 0 | 0 | 0 |
| Without malaise symptoms (people) | 50 | 50 | 50 | 50 | 50 |
Safety testing result proves that the skin care compositions prepared according to the method for embodiment 1 to embodiment 5 pacifies human skin
Entirely, nonirritant.
Above-described embodiment technical solution for explaining the present invention, must not believe that the protection scope of technical solution of the present invention
It is limited to embodiment.The non-creative modifications and adaptations that those skilled in the art make based on the technical solution of the present invention are equal
It falls under the scope of the present invention.
Claims (8)
1. a kind of skin care compositions, which is characterized in that including following component according to the mass fraction: polyol humectant 2-20
Part, 0.05-0.4 parts of Sodium Hyaluronate, 0-0.2 parts of xanthan gum, 0.5-2.5 parts of trehalose, 0-0.6 parts of antioxidant, surplus is
Water.
2. skin care compositions according to claim 1, which is characterized in that the polyol humectant is selected from glycerol, poly- second
One of glycol, propylene glycol, butanediol are a variety of.
3. skin care compositions according to claim 2, which is characterized in that matter of the glycerol in the skin care compositions
Measuring number is 2-5 parts, and mass fraction of the polyethylene glycol in the skin care compositions is 0-5 parts, and the propylene glycol is in institute
Stating the mass fraction in skin care compositions is 0-5 parts, and mass fraction of the butanediol in the skin care compositions is 0-5
Part.
4. skin care compositions according to claim 1, which is characterized in that the antioxidant is selected from sodium sulfite, sulfurous
One of sour hydrogen sodium, tea polyphenols are a variety of.
5. skin care compositions according to claim 4, which is characterized in that the sodium sulfite is in the skin care compositions
Mass fraction be 0-0.2 part, mass fraction of the sodium hydrogensulfite in the skin care compositions be 0-0.2 parts, it is described
Mass fraction of the tea polyphenols in the skin care compositions is 0-0.2 parts.
6. the preparation method of skin care compositions as described in claim 1, which comprises the steps of:
(1) polyol humectant, Sodium Hyaluronate, xanthan gum, antioxidant are added in reaction kettle and are stirred evenly, added water, stir
It mixes and is heated to 70 DEG C；
(2) after polyol humectant, Sodium Hyaluronate, xanthan gum, antioxidant all dissolution, trehalose, stirring drop is added
Temperature；
(3)≤40 DEG C are down to temperature, discharging is filling；
(4) after the completion of filling, 8-25Kgy Co60Irradiation sterilization is to get the skin care compositions.
7. the preparation method of skin care compositions according to claim 6, which is characterized in that the sterilizing methods in step (4)
It can also be electron beam irradiation sterilization, irradiation dose 8-25Kgy.
8. application of the skin care compositions in moisturizing by spraying, in moisture retention water, essence lotion, lotion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910663116.6A CN110251423A (en) | 2019-07-22 | 2019-07-22 | A kind of skin care compositions and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910663116.6A CN110251423A (en) | 2019-07-22 | 2019-07-22 | A kind of skin care compositions and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110251423A true CN110251423A (en) | 2019-09-20 |
Family
ID=67927670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910663116.6A Pending CN110251423A (en) | 2019-07-22 | 2019-07-22 | A kind of skin care compositions and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110251423A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111643399A (en) * | 2020-08-04 | 2020-09-11 | 西安朴若医疗科技有限公司 | Antioxidant skin care composition containing levovitamin C and preparation method thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104257682A (en) * | 2014-10-28 | 2015-01-07 | 天津嘉氏堂科技有限公司 | Wound surface repairing composition and preparation |
| CN107375032A (en) * | 2017-08-11 | 2017-11-24 | 天津嘉氏堂科技有限公司 | A kind of composition and preparation method for repairing skin barrier |
| CN107375080A (en) * | 2017-08-04 | 2017-11-24 | 遵义医学院 | A kind of white tea moisturizing sleep mask and preparation method thereof |
| CN107519123A (en) * | 2017-09-30 | 2017-12-29 | 广州昕生医学材料有限公司 | Face repairs anti-inflammatory composition and its application |
| CN107898660A (en) * | 2017-10-10 | 2018-04-13 | 广州柏俐臣化妆品有限公司 | A kind of tender skin water light stoste and its preparation method and application |
| CN108186377A (en) * | 2018-03-19 | 2018-06-22 | 青岛溯博生物技术有限公司 | Natural materials composite facial mask powder, facial mask and preparation method |
| CN109998940A (en) * | 2019-03-28 | 2019-07-12 | 广州市茗妍化妆品有限公司 | A kind of moisture retention water and preparation method thereof |
-
2019
- 2019-07-22 CN CN201910663116.6A patent/CN110251423A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104257682A (en) * | 2014-10-28 | 2015-01-07 | 天津嘉氏堂科技有限公司 | Wound surface repairing composition and preparation |
| CN107375080A (en) * | 2017-08-04 | 2017-11-24 | 遵义医学院 | A kind of white tea moisturizing sleep mask and preparation method thereof |
| CN107375032A (en) * | 2017-08-11 | 2017-11-24 | 天津嘉氏堂科技有限公司 | A kind of composition and preparation method for repairing skin barrier |
| CN107519123A (en) * | 2017-09-30 | 2017-12-29 | 广州昕生医学材料有限公司 | Face repairs anti-inflammatory composition and its application |
| CN107898660A (en) * | 2017-10-10 | 2018-04-13 | 广州柏俐臣化妆品有限公司 | A kind of tender skin water light stoste and its preparation method and application |
| CN108186377A (en) * | 2018-03-19 | 2018-06-22 | 青岛溯博生物技术有限公司 | Natural materials composite facial mask powder, facial mask and preparation method |
| CN109998940A (en) * | 2019-03-28 | 2019-07-12 | 广州市茗妍化妆品有限公司 | A kind of moisture retention water and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 丁红等: "《中华医药研究与实践》", 30 September 1996, 山西科学技术出版社 * |
| 范霁红等: "《中国核技术仪器设备学科发展研究报告》", 31 March 2016, 原子能出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111643399A (en) * | 2020-08-04 | 2020-09-11 | 西安朴若医疗科技有限公司 | Antioxidant skin care composition containing levovitamin C and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108685759A (en) | A kind of composition of hyaluronic acid substance and tetrahydropyrimidine substance | |
| KR101068151B1 (en) | Composition comprising of plant extract having antimicrobial and antiseptic activity and the use thereof | |
| CN111228200B (en) | Whitening composition, whitening essence containing whitening composition and preparation method of whitening essence | |
| CN106619186B (en) | Preparation for protecting activity of superoxide dismutase and preparation method thereof | |
| CN109199962A (en) | A kind of acne-removing composition and cosmetics | |
| CN105168054A (en) | Mask capable of supplementing water, whitening and removing wrinkles and preparation method of mask | |
| CN115569105B (en) | Composition containing rice hull extract for removing dandruff, controlling oil, inhibiting bacteria and removing mites | |
| CN108042380A (en) | A kind of infant's activity stern protection cream and preparation method thereof | |
| CN108261376A (en) | A kind of three-dimensional moisturizing factor | |
| CN110403877A (en) | Liquid containing carbohydrate and vinasse | |
| CN108542801A (en) | A kind of skin care patch Essence of preservative free | |
| CN106109264B (en) | A kind of facial treatment mask and preparation method thereof with anti-bacteria wet keeping function | |
| CN112006958A (en) | Depilatory cream and preparation method thereof | |
| CN110251423A (en) | A kind of skin care compositions and preparation method thereof | |
| CN108125810A (en) | A kind of compound moisturizing remediation composition and its preparation method and application | |
| CN109481391A (en) | A kind of Baby Care cream and preparation method thereof compounding silver ion and green phenol song | |
| CN112587426A (en) | Whitening and freckle removing essence and preparation method thereof | |
| CN109381375B (en) | Essential oil composition for scalp care and application | |
| JP2001139484A (en) | Dermal agent for external use | |
| CN104436116B (en) | A kind of rosemary lavipeditum powder and preparation method thereof | |
| KR101736478B1 (en) | Method for manufacturing lotions with effective in treating acne | |
| CN108670926A (en) | Moisturizing composition and skin care product containing same | |
| CN108324648A (en) | A kind of composition of anti-acne | |
| CN114259415A (en) | Acid-transmitting skin-refreshing and repairing facial mask | |
| CN107789282A (en) | A kind of skin care item containing dendrobium candidum extract and plant whitening element and its preparation method and application |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190920 |