CN111991287B

CN111991287B - High-moisturizing facial cream

Info

Publication number: CN111991287B
Application number: CN202010886045.9A
Authority: CN
Inventors: 张永梅; 许兰英
Original assignee: Tongfu Group China Co ltd
Current assignee: Tongfu Group China Co ltd
Priority date: 2020-08-28
Filing date: 2020-08-28
Publication date: 2023-05-05
Anticipated expiration: 2040-08-28
Also published as: CN111991287A

Abstract

The invention relates to the technical field of cosmetics, in particular to high-moisture-retention face cream which comprises active substances and a face cream matrix, wherein the active substances comprise the following components in percentage by weight: 0.5-2wt% of goldfish algae extract, 1-3wt% of white bone extract, 0.03-0.1wt% of gamma-polyglutamic acid and 0.2-1.5wt% of fungal polysaccharide. The goldfish algae extract can enhance the water retention and humidity of the skin and dynamically adjust the water-oil balance in the skin; the gamma-polyglutamic acid can form a smooth, elastic and self-moisturizing soft film on the surface of the skin; the fungus polysaccharide can penetrate deep into the skin, improve the skin activity, promote the absorption of the skin to nutrient substances, delay the skin aging, and in addition, the fungus polysaccharide also has strong water absorption and moisture retention effects, enhances the skin elasticity, forms a moisture retention barrier on the surface layer of the skin, and achieves the long-term moisture retention effect; the four substances are matched, so that the effects of deep moisturizing and long-acting moisturizing of the skin can be achieved.

Description

High-moisturizing facial cream

Technical Field

The invention relates to the technical field of cosmetics, in particular to a high-moisturizing facial cream.

Background

In modern society, the temperature change and pressure caused by air conditioning, environmental pollution and season change, skin aging, metabolism slowing and other factors can cause skin moisture loss, so that the skin is rough, dull, dry, and various skin problems are caused. The skin problems caused by lack of water are never as simple as dryness, almost every skin problem is related to water replenishment and retention. Moisture is the first element of skin beauty, and whitening, sun protection, oil control and the like are all completed on the basis of moisturizing. The skin problems of any season, age and skin can be perfectly realized in soothing and moistening water. Therefore, the moisturizing work of the skin is very important.

The face cream is a repairing component containing various anti-aging, moisturizing, curing and the like, and has different effects, and the effect of each effect is obvious. The moisturizing cream is one of the moisturizing creams, and the principle is based on the fact that the moisturizing cream is high in moisture content, is easy to spread evenly, and can quickly permeate into the epidermis of the skin, so that components for moisturizing the skin are easy to be reserved, are not easy to evaporate, and maintain a certain moisture content of the skin, the moisturizing purpose is achieved, moisture can easily permeate into the stratum corneum of the epidermis after the moisturizing cream is spread, the skin becomes soft, and the skin is natural, bright and elastic.

At present, the most moisturizing hyaluronic acid is added into face cream by people to moisturize the face, but the moisturizing capability of the hyaluronic acid still cannot meet the requirements of most people.

Disclosure of Invention

The invention aims to solve the problem of limited moisturizing ability of the face cream in the prior art and provides the face cream with high moisturizing ability.

In order to achieve the above object, the present invention provides, in one aspect, a highly moisturizing facial cream comprising an active substance and a facial cream base, the active substance comprising, based on the total amount of the highly moisturizing facial cream: 0.5-2wt% of goldfish algae extract, 1-3wt% of white bone extract, 0.03-0.1wt% of gamma-polyglutamic acid and 0.2-1.5wt% of fungal polysaccharide.

The inventor of the invention discovers that the goldfish algae extract can enhance the water retention and humidity of the skin, can dynamically adjust the water-oil balance in the skin, enables the skin to be more moist, has good repairing effect, has good repairing capability and can improve subcutaneous damaged tissues; the gamma-polyglutamic acid can form a smooth, elastic and self-moisturizing soft film on the surface of the skin; the fungus polysaccharide can penetrate deep into the skin, improve the skin activity, promote the absorption of the skin to nutrient substances, delay the skin aging, and in addition, the fungus polysaccharide also has strong water absorption and moisture retention effects, enhances the skin elasticity, forms a moisture retention barrier on the surface layer of the skin, and achieves the long-term moisture retention effect; the four substances are matched, so that the effects of deep moisturizing and long-acting moisturizing of the skin can be achieved.

In order to further enhance the moisturizing effect of the highly moisturizing creams, preferably, the active substance comprises: 0.8-1.2wt% of goldfish algae extract, 1.2-2.5wt% of white bone extract, 0.06-0.08wt% of gamma-polyglutamic acid and 0.5-1wt% of fungal polysaccharide.

In order to further improve the moisturizing effect of the high moisturizing facial cream, under the preferred condition, the weight ratio of the goldfish algae extract to the white bone extract to the fungal polysaccharide is 1:0.8-3.5:0.15-1.6; further preferably, the weight ratio of the goldfish algae extract, the white bone extract and the fungal polysaccharide is 1:1-2:0.6-1.

In order to further improve the moisturizing effect of the high moisturizing facial cream, under the preferred condition, the fungus polysaccharide is selected from at least one of tremella polysaccharide, ganoderma lucidum polysaccharide, indian truffle, boletus polysaccharide, flammulina velutipes polysaccharide, lentinan, morchella polysaccharide, dictyophora indusiata polysaccharide, hericium erinaceus polysaccharide and tricholoma matsutake polysaccharide; further preferred, the fungal polysaccharide comprises, based on the total amount of the fungal polysaccharide: the inventor discovers that the tremella polysaccharide, the ganoderma lucidum polysaccharide, the morchella polysaccharide, the bamboo fungus polysaccharide and the hericium erinaceus polysaccharide have the best moisturizing effect when the weight ratio of the tremella polysaccharide to the ganoderma lucidum polysaccharide to the weight ratio of the morchella polysaccharide to the hericium erinaceus polysaccharide is 1:0.1-0.5:0.2-0.5:0.2-1.2 is 1:0.2-1.2.

In order to further improve the moisturizing effect of the cream, the active substance preferably further comprises: 1 to 5 weight percent of fibroin, 0.1 to 0.8 weight percent of ceramide, 0.3 to 1.5 weight percent of transdermal peptide EFG, 0.1 to 2.8 weight percent of sodium alginate, 5 to 15 weight percent of sodium hyaluronate and 0.2 to 0.5 weight percent of squalane.

The fibroin can form a compact protein film on the face, so that active ingredients in the moisturizing facial cream are blocked in the skin, nutrient loss is avoided, and the long-acting moisturizing effect is achieved.

Further preferably, the molecular weight of the sodium hyaluronate is 2-10Kd.

According to the invention, the cream base further comprises at least one of activated carbon, plant essential oil, skin repair agent, surfactant, essence, emulsifier, antioxidant, preservative, sunscreen agent, chelating agent, thickener, humectant.

Wherein the plant essential oil is at least one selected from the group consisting of rose essential oil, camellia essential oil, lemon essential oil, lavender essential oil, calendula oil and geranium essential oil.

In order to improve the restoration ability of the highly moisturizing cream, preferably, the skin restoration agent is selected from at least one of glycine, alanine, valine, isoleucine, leucine, proline, arginine, aspartic acid, glutamic acid, L-threonine, citric acid, and betaine.

The emulsifier may be known to those skilled in the art, and for example, the emulsifier may be at least one of polyglyceryl-6 distearate, tribasic behenate PEG-20 esters, cetostearyl glucoside, polyglyceryl-3 methyl glucose distearate, cetostearyl oleate, polysorbate-20, glyceryl stearate, PEG-100 stearate, coco glucoside, polyacrylamide, C13-14 isoparaffin, laureth-7, sodium acrylate/sodium acryloyldimethyl taurate copolymer, polysorbate-80 and sorbitan olivate, and the emulsifier is added in an amount of 1-2wt% of the total amount of the high moisturizing cream.

The preservative may be known to those skilled in the art, and for example, the preservative may be at least one of methylparaben, propylparaben, phenoxyethanol, benzyl alcohol, sodium benzoate, potassium sorbate, anisic acid, and sodium acetylmaleate, and the added amount thereof is 0.1-0.5wt% of the total amount of the highly moisturizing facial cream.

The chelating agent may be known to those skilled in the art, for example, the chelating agent may be disodium EDTA and/or tetrasodium EDTA; the addition amount of the chelating agent is 0.02-0.06wt% of the total amount of the high moisture-preserving facial cream.

The thickener may be at least one of cetostearyl alcohol, beeswax, stearic acid, carbomer, xanthan gum, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, acrylic acid (ester) type/C10-30 alkanol acrylate cross-linked polymer, ammonium acryloyldimethyl taurate/VP copolymer, for example, in an amount of 0.5 to 2.5wt% based on the total amount of the highly moisturizing cream.

The humectant can be known to those skilled in the art, and can be at least one of polyethylene glycol, polypropylene glycol, butanediol, propylene glycol, glycerol, hexylene glycol, xylitol, sorbitol and the like, and the addition amount of the humectant is 2-10wt% of the total amount of the high moisture-retention face cream.

Through the technical scheme, the invention has the following technical effects:

the goldfish algae extract can enhance the water retention and humidity of the skin, dynamically adjust the water-oil balance in the skin, enable the skin to be more moist, have good repairing effect, and the white bone extract has good repairing capability and can improve subcutaneous damaged tissues; the gamma-polyglutamic acid can form a smooth, elastic and self-moisturizing soft film on the surface of the skin; the fungus polysaccharide can penetrate deep into the skin, improve the skin activity, promote the absorption of the skin to nutrient substances, delay the skin aging, and in addition, the fungus polysaccharide also has strong water absorption and moisture retention effects, enhances the skin elasticity, forms a moisture retention barrier on the surface layer of the skin, and achieves the long-term moisture retention effect; the four substances are matched, so that the effects of deep moisturizing and long-acting moisturizing of the skin can be achieved.

Detailed Description

The endpoints and any values of the ranges disclosed herein are not limited to the precise range or value, and are understood to encompass values approaching those ranges or values. For numerical ranges, one or more new numerical ranges may be found between the endpoints of each range, between the endpoint of each range and the individual point value, and between the individual point value, in combination with each other, and are to be considered as specifically disclosed herein.

The present invention will be described in detail by examples.

Sodium hyaluronate was purchased from western An Xu full Biotechnology Co., ltd., product number 9067-32-7.

The goldfish algae extract is extracted from goldfish algae by a supercritical carbon dioxide method, and the supercritical carbon dioxide method has the following technological conditions: the extraction pressure is 30Mpa, the temperature is 60 ℃, the carbon dioxide flow rate is 1.5L/min, the extraction time is 60min, the separation I pressure is 5Mpa, the temperature is 60 ℃, the separation II pressure is 5Mpa, the temperature is 60 ℃, and the entrainer is 1 times of 95% ethanol.

The white bone extract is extracted from white bone by a microwave extraction method, and the process conditions of the microwave extraction method are as follows: ethanol is used as an extraction solvent, the liquid-material ratio is 1:6, the microwave power is 500W, the extraction time is 30min, and the microwave extraction product is further purified by adopting a gradient elution HPLC method (the mobile phase is acetonitrile acetate), so as to obtain the white bone extract.

In the following examples, the composition of fungal polysaccharide a is: 8 parts of tremella polysaccharide, 2 parts of ganoderma lucidum polysaccharide, 1 part of Indian truffle, 8 parts of boletus polysaccharide, 6 parts of flammulina velutipes polysaccharide, 1 part of lentinan, 1 part of morchella polysaccharide, 7 parts of bamboo fungus polysaccharide, 6 parts of hericium erinaceus polysaccharide and 2 parts of tricholoma matsutake polysaccharide.

The composition of the fungal polysaccharide B is as follows: 5 parts of tremella polysaccharide, 1 part of ganoderma polysaccharide, 1 part of Indian truffle, 3 parts of boletus polysaccharide, 5 parts of flammulina velutipes polysaccharide, 2 parts of lentinan, 3 parts of morchella polysaccharide, 3 parts of bamboo fungus polysaccharide, 8 parts of hericium erinaceus polysaccharide and 1 part of tricholoma matsutake polysaccharide.

The composition of the fungal polysaccharide C is: 10 parts of tremella polysaccharide, 5 parts of ganoderma lucidum polysaccharide, 3 parts of Indian truffle, 5 parts of boletus polysaccharide, 9 parts of flammulina velutipes polysaccharide, 6 parts of lentinan, 5 parts of morchella polysaccharide, 2 parts of bamboo fungus polysaccharide, 2 parts of hericium erinaceus polysaccharide and 10 parts of tricholoma matsutake polysaccharide.

Examples 1 to 5

The contents of the substances in the creams of examples 1 to 5 are shown in Table 1, and the high moisturizing creams provided in examples 1 to 5 are shown in Table 2.

TABLE 1

Example 6

The procedure of example 1 was followed, except that: the high moisturizing facial cream performance provided in this example is shown in table 2 using fungal polysaccharide B instead of fungal polysaccharide a.

Example 7

The procedure of example 1 was followed, except that: the high moisturizing facial cream performance provided in this example is shown in table 2 using fungal polysaccharide C instead of fungal polysaccharide a.

Example 8

The procedure of example 1 was followed, except that: the performance of the high moisturizing facial cream provided in this example is shown in Table 2 using flammulina velutipes polysaccharide instead of fungal polysaccharide A.

Comparative example 1

The procedure of example 1 was followed, except that: the high moisturizing facial cream provided in this example, which does not contain the goldfish algae extract, has the performance shown in table 2.

Comparative example 2

The procedure of example 1 was followed, except that: the high moisturizing facial cream provided in this example, without the white bone extract, has the properties shown in Table 2.

Comparative example 3

The procedure of example 1 was followed, except that: the performance of the highly moisturizing creams provided in this example, which does not contain gamma-polyglutamic acid, is shown in Table 2.

Comparative example 4

The procedure of example 1 was followed, except that: the high moisturizing facial cream performance provided in this example, without fungal polysaccharide A, is shown in Table 2.

Blank examples

The procedure of example 1 was followed, except that: the high moisturizing facial cream provided in this example does not contain Goldfish algae extract, white bone extract, gamma-polyglutamic acid and fungal polysaccharide A, and the performance of the facial cream is shown in Table 2.

Test case

130 female volunteers with 20-35 years old and without allergy history were selected and divided into 13 groups of 10 persons each, and the highly moisturizing creams prepared in examples 1-8, comparative examples 1-4 and blank examples were tested respectively. All subjects had signed an informed consent form.

The left forearm of the subject is used as the tested part, the cream sample is smeared for 1 time in the morning and evening every day, the skin reaction is observed for 24 hours by lightly massaging with fingers until the skin reaction is completely absorbed, and the right forearm of the subject is used as a blank control.

Results: after detection, the product has good smell and stability, and all subjects have no abnormal phenomena such as erythema, and the like, and the result is still free from any reaction after continuous observation for 3-4 days, which indicates that the cream prepared by the technical scheme is safe.

When the test is carried out, the inner side area of the left forearm of the subject is taken as a tested part, the tested part is cleaned by clear water before the test and is stabilized for 30min before the test, the test temperature is 20-25 ℃, the relative humidity is 50-60%, the tested part is smeared with face cream, the massage is carried out until the absorption, the intelligent moisture tester is used for measuring the moisture percentage of the tested part before the use and after the use for 0h, 2h, 4h and 8h, the test is repeated 5 times each time, the average value is obtained, and the experimental result is shown in the table 2.

TABLE 2

	Before use/%	0h/％	2h/％	4h/％	8h/％
						Example 1	32.6±1.1	77.5±1.9	72.3±3.6	69.5±2.6	58.3±1.9
Example 2	31.8±0.8	76.3±2.8	71.0±3.1	68.4±3.2	54.9±2.6
						Example 3	29.5±1.1	75.1±3.7	69.8±3.8	65.9±3.5	58.7±1.9
Example 4	28.6±1.2	73.2±3.5	68.7±2.8	61.8±2.7	54.9±2.6
						Example 5	30.5±0.9	72.1±2.8	65.4±2.9	60.4±2.5	55.4±3.4
Example 6	32.1±1.4	69.3±1.9	60.3±3.0	58.4±2.4	49.3±2.5
						Example 7	29.5±1.5	68.2±2.7	60.7±3.4	57.3±2.9	48.5±2.8
Example 8	30.8±1.1	68.7±3.6	59.8±2.6	54.1±2.4	45.9±2.9
						Comparative example 1	31.4±0.9	65.3±2.8	52.1±2.5	49.2±2.8	40.8±3.1
Comparative example 2	32.5±0.8	64.7±4.1	53.7±3.7	48.3±3.4	37.8±3.2
						Comparative example 3	30.4±1.3	60.2±3.2	49.3±1.8	46.3±2.9	38.7±2.7
Comparative example 4	31.7±2.5	63.9±2.3	56.7±2.6	41.3±2.7	36.4±2.5
						Blank examples	31.5±1.2	55.4±3.6	45.7±2.4	36.6±2.6	32.2±2.6

The preferred embodiments of the present invention have been described in detail above, but the present invention is not limited thereto. Within the scope of the technical idea of the invention, a number of simple variants of the technical solution of the invention are possible, including combinations of the individual technical features in any other suitable way, which simple variants and combinations should likewise be regarded as being disclosed by the invention, all falling within the scope of protection of the invention.

Claims

1. A highly moisturizing facial cream comprising an active substance and a facial cream base, characterized in that the active substance comprises, based on the total amount of the highly moisturizing facial cream: 0.5-2wt% of goldfish algae extract, 1-3wt% of white bone extract, 0.03-0.1wt% of gamma-polyglutamic acid and 0.2-1.5wt% of fungal polysaccharide;

the composition of the fungal polysaccharide is as follows: 8 parts of tremella polysaccharide, 2 parts of ganoderma lucidum polysaccharide, 1 part of Indian truffle polysaccharide, 8 parts of boletus polysaccharide, 6 parts of flammulina velutipes polysaccharide, 1 part of lentinan, 1 part of morchella polysaccharide, 7 parts of bamboo fungus polysaccharide, 6 parts of hericium erinaceus polysaccharide and 2 parts of tricholoma matsutake polysaccharide.

2. The high moisturizing facial cream of claim 1, wherein the active comprises: 0.8-1.2wt% of goldfish algae extract, 1.2-2.5wt% of white bone extract, 0.06-0.08wt% of gamma-polyglutamic acid and 0.5-1wt% of fungal polysaccharide.

3. The high moisturizing facial cream of claim 1, wherein the weight ratio of the goldfish algae extract, the white bone extract and the fungal polysaccharide is 1:0.8-3.5:0.15-1.6.

4. A highly moisturizing facial cream according to claim 3, wherein the weight ratio of goldfish algae extract, white bone extract and fungal polysaccharide is 1:1-2:0.6-1.

5. The high moisturizing facial cream of claim 1, wherein the active further comprises: 1 to 5 weight percent of fibroin, 0.1 to 0.8 weight percent of ceramide, 0.3 to 1.5 weight percent of transdermal peptide EFG, 0.1 to 2.8 weight percent of sodium alginate, 5 to 15 weight percent of sodium hyaluronate and 0.2 to 0.5 weight percent of squalane.

6. The high moisturizing facial cream of claim 5, wherein the sodium hyaluronate has a molecular weight of 2-10Kd.

7. The high moisturizing facial cream of claim 1, wherein the facial cream base further comprises at least one of activated carbon, plant essential oils, skin restoration agents, fragrances, emulsifiers, antioxidants, preservatives, sunscreens, chelating agents, thickeners, humectants, gels, and suds boosters.