CN111671708A - Probiotic compound cosmetic for balancing and repairing skin and preparation method thereof - Google Patents
Probiotic compound cosmetic for balancing and repairing skin and preparation method thereof Download PDFInfo
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract
The invention provides a probiotic compound cosmetic for balancing and repairing skin and a preparation method thereof, wherein the probiotic compound cosmetic comprises an active substance and a cosmetic basic substance, and the active substance comprises the following components in percentage by weight: 15-32% of a secondary fission yeast fermentation product filtrate, 12-16% of a hyaluronic acid composition, 5-8% of resveratrol, 10-15% of a chicory stem extract, 3-6% of a bletilla striata extract and the balance of a lactic acid bacteria/mung bean seed extract fermentation product filtrate. The hyaluronic acid composition comprises the following components in percentage by weight: 18-25% of sodium hyaluronate cross-linked polymer, 20-28% of sodium hyaluronate, 16-23% of acetylated sodium hyaluronate and the balance of hydrolyzed sodium hyaluronate. The active substances of the cosmetic disclosed by the invention are matched with each other, so that the skin can be repaired, the water-oil balance is kept, the moisturizing effect is good, and the skin can be kept moist for a long time.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to a probiotic compound cosmetic for balancing and repairing skin and a preparation method thereof.
Background
The cosmetic is a chemical industrial product or a fine chemical product which is applied to any part of the surface of a human body, such as skin, hair, nails, lips and teeth, by smearing, spraying or the like, so as to achieve the purposes of cleaning, maintaining, beautifying, decorating and changing the appearance, or correcting the odor of the human body and keeping a good state.
With the continuous improvement of living standard, the requirements of people on skin care are also continuously improved. During the metabolism process, the human body forms various free radicals. Among them, 95% of free radicals are harmful oxygen radicals. They attack cells, produce oxidation, damage cell function, reduce human vitality, and make face have aging phenomena such as wrinkle and mottle, and make skin become dull. And when the temperature is high in summer, the moisture loss of the skin is serious, and the skin can secrete a large amount of grease to prevent the further loss of moisture. When a lot of oil is produced on the face, the skin is greasy and bright, the feeling of greasiness and stickiness exists, and the mind of dysphoria and depression is easy to generate. In addition, the urban pollution is serious, and the oil is too large to block pores and adhere dust and dirt to the pores, so that skin infection, acne and the like are caused.
The skin health is maintained, firstly, the water-oil balance of the skin is maintained, the water-oil balance of the skin refers to the most healthy and ideal state that the skin is not oily and dry, the pH value is 5-5.6, the secretion amount of sweat glands and sebaceous glands is moderate, and the skin is in a neutral state that the skin is not greasy and dry, so that the skin is ruddy and fine and is not sensitive to external stimulation.
After the face is cleaned, the toner is the first cosmetic used in skin care, can be used for re-cleaning the skin and conditioning the pH value of the skin, can quickly supplement the moisture of the skin, and has an important effect on the oil-water balance of the skin. However, the existing toner has simple effective components, weak effect of maintaining water-oil balance of skin and poor effect of repairing skin.
Disclosure of Invention
The invention aims to provide a probiotic compound cosmetic for balancing and repairing skin and a preparation method thereof.
In order to achieve the purpose, the invention is realized by the following technical scheme:
the probiotic compound cosmetic for balancing and repairing the skin comprises an active substance and a cosmetic basic substance, wherein the active substance comprises the following components in percentage by weight: 15-32% of a secondary fission yeast fermentation product filtrate, 12-16% of a hyaluronic acid composition, 5-8% of resveratrol, 10-15% of a chicory stem extract, 3-6% of a bletilla striata extract and the balance of a lactic acid bacteria/mung bean seed extract fermentation product filtrate.
Preferably, the hyaluronic acid composition consists of the following components in percentage by weight: 18-25% of sodium hyaluronate cross-linked polymer, 20-28% of sodium hyaluronate, 16-23% of acetylated sodium hyaluronate and the balance of hydrolyzed sodium hyaluronate.
Preferably, the chicory stem extract is prepared by the following method:
(1) pulverizing fresh herba Cichorii stem, adding 60-70% ethanol 13-15 times the volume of herba Cichorii stem, and extracting at 55-65 deg.C for 70-100 min; then filtering to obtain an extracting solution;
(2) adjusting pH of the obtained extractive solution to 5-6, adding 3-5% of active carbon into the extractive solution, stirring at room temperature for 40-50min, and filtering to obtain filtrate;
(3) concentrating the filtrate under reduced pressure to obtain concentrated solution, loading the concentrated solution into a chromatographic column by a wet method, collecting eluent, filtering the eluent by using a 0.45 mu m filter membrane, concentrating the obtained filtrate under reduced pressure, and removing the solvent to obtain the extract of the chicory stem.
Preferably, the bletilla striata extract is prepared by the following method:
(1) pulverizing dried rhizoma Bletillae, adding ethanol with volume fraction of 50-60% 18-23 times of rhizoma Bletillae, and extracting at 70-80 deg.C for 60-80 min; then filtering to obtain an extracting solution;
(2) adjusting pH of the obtained extractive solution to 5-6, adding 5-6% of active carbon into the extractive solution, stirring at room temperature for 40-50min, and filtering to obtain filtrate;
(3) concentrating the filtrate under reduced pressure to obtain concentrated solution, loading the concentrated solution into a chromatographic column with stationary phase of polyamide resin and eluent of 60-70% ethanol by mass fraction, collecting eluent, filtering the eluent with 0.45 μm filter membrane, concentrating the filtrate under reduced pressure, and removing solvent to obtain rhizoma bletilla extract.
Preferably, the cosmetic basic substance consists of the following components in percentage by weight: 4-8% of absolute ethyl alcohol, 2-4% of 1, 3-butanediol, 3-5% of glycerol, 0.02-0.06% of menthol, 0.1-0.3% of allantoin, 0.03-0.08% of citric acid and the balance of water.
Preferably, the mass ratio of the active substance to the cosmetic basic substance is 60 to 100.
The preparation method of the probiotic compound cosmetic for balancing and repairing skin comprises the following steps:
(1) weighing the secondary fission yeast fermentation product filtrate, the hyaluronic acid composition, the resveratrol, the chicory stem extract, the bletilla striata extract and the lactobacillus/mung bean seed extract fermentation product filtrate according to the proportion, and uniformly mixing the raw materials to obtain an active substance;
(2) weighing anhydrous ethanol, 1, 3-butanediol, glycerol, menthol, allantoin, citric acid and water in proportion, and mixing the above raw materials uniformly to obtain cosmetic basic substance;
(3) adding the active substances into cosmetic basic substances in proportion, and stirring well to obtain the final product.
The invention has the beneficial effects that:
in the invention, the effective components of the extract comprise a secondary fission yeast fermentation product filtrate, a hyaluronic acid composition, resveratrol, a chicory stem extract, a bletilla striata extract and a lactic acid bacteria/mung bean seed extract fermentation product filtrate. The secondary split yeast fermentation product filtrate and the lactobacillus/mung bean seed extract fermentation product filtrate contain rich amino acids, polypeptides, minerals and various vitamins, can effectively improve skin conditions, have a good skin repairing effect, and have a certain effect of maintaining water-oil balance of skin. The hyaluronic acid composition has good moisturizing effect, and can repair skin and make skin more tender and smooth. The added resveratrol has strong antioxidant and anti-free radical effects, good anti-aging effect and good effect of maintaining water and oil balance of skin. On the basis, the added specific chicory stem extract and bletilla striata extract can regulate grease secretion, keep the water-oil balance of skin and have good anti-aging effect.
In the invention, the active substances are matched with each other, so that the skin can be repaired, the water-oil balance is kept, the moisturizing effect is good, and the skin can be kept moist for a long time. When the cosmetic toner is prepared, a proper amount of anhydrous ethyl, 1, 3-butanediol, glycerol, menthol, allantoin, citric acid and water are added, so that the prepared product has stable performance and good use effect.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
a probiotic compound cosmetic for balancing and repairing skin comprises active substance and cosmetic basic substance. The mass ratio of the active substance to the cosmetic basic substance is 1: 80.
the active substance comprises the following components in percentage by weight: 28% of a secondary fission yeast fermentation product filtrate, 13% of a hyaluronic acid composition, 8% of resveratrol, 15% of a chicory stem extract, 6% of a bletilla striata extract and the balance of a lactic acid bacteria/mung bean seed extract fermentation product filtrate. The hyaluronic acid composition comprises the following components in percentage by weight: 25% of sodium hyaluronate cross-linked polymer, 25% of sodium hyaluronate, 20% of acetylated sodium hyaluronate and the balance of hydrolyzed sodium hyaluronate.
The cosmetic basic substance comprises the following components in percentage by weight: 6% of absolute ethyl alcohol, 3% of 1, 3-butanediol, 4% of glycerol, 0.05% of menthol, 0.2% of allantoin, 0.05% of citric acid and the balance of water.
The chicory stem extract is prepared by the following method:
(1) taking fresh chicory stems as raw materials, crushing, adding ethanol with volume fraction of 70% 13 times of the chicory stems, and extracting at 55 ℃ for 100 min; then filtering to obtain an extracting solution.
(2) Adjusting pH of the obtained extractive solution to 6, adding 5% of active carbon into the extractive solution, stirring at room temperature for 45min, and filtering to obtain filtrate.
(3) Concentrating the filtrate under reduced pressure to obtain concentrated solution, loading the concentrated solution into a chromatographic column by a wet method, collecting eluent, filtering the eluent by using a 0.45 mu m filter membrane, concentrating the obtained filtrate under reduced pressure, and removing the solvent to obtain the extract of the stem of the chicory.
The bletilla striata extract is prepared by the following method:
(1) pulverizing dried rhizoma Bletillae, adding 23 times of 60% ethanol, and extracting at 70 deg.C for 70 min; then filtering to obtain an extracting solution.
(2) Adjusting pH of the obtained extractive solution to 6, adding 5% of active carbon into the extractive solution, stirring at room temperature for 50min, and filtering to obtain filtrate.
(3) Concentrating the filtrate under reduced pressure to obtain concentrated solution, loading the concentrated solution into a chromatographic column with stationary phase of polyamide resin and eluent of 70% ethanol by mass fraction, collecting eluent, filtering the eluent with 0.45 μm filter membrane, concentrating the filtrate under reduced pressure, and removing solvent to obtain rhizoma bletilla extract.
Example 2:
a probiotic compound cosmetic for balancing and repairing skin comprises active substance and cosmetic basic substance. The mass ratio of the active substance to the cosmetic basic substance is 1: 80.
the active substance comprises the following components in percentage by weight: 25% of secondary fission yeast fermentation product filtrate, 13% of hyaluronic acid composition, 6% of resveratrol, 15% of chicory stem extract, 6% of bletilla striata extract and the balance of lactobacillus/mung bean seed extract fermentation product filtrate. The hyaluronic acid composition comprises the following components in percentage by weight: 22% of sodium hyaluronate cross-linked polymer, 22% of sodium hyaluronate, 18% of acetylated sodium hyaluronate and the balance of hydrolyzed sodium hyaluronate.
The cosmetic basic substance comprises the following components in percentage by weight: 8% of absolute ethyl alcohol, 4% of 1, 3-butanediol, 4% of glycerol, 0.05% of menthol, 0.15% of allantoin, 0.05% of citric acid and the balance of water.
The chicory stem extract is prepared by the following method:
(1) taking fresh chicory stems as raw materials, crushing, adding ethanol with volume fraction of 60% 15 times of the chicory stems, and extracting at 65 ℃ for 80 min; then filtering to obtain an extracting solution.
(2) Adjusting pH of the obtained extractive solution to 5, adding 3% of active carbon into the extractive solution, stirring at room temperature for 40min, and filtering to obtain filtrate.
(3) Concentrating the filtrate under reduced pressure to obtain concentrated solution, loading the concentrated solution into a chromatographic column by a wet method, collecting eluent, filtering the eluent by using a 0.45 mu m filter membrane, concentrating the obtained filtrate under reduced pressure, and removing the solvent to obtain the extract of the stem of the chicory.
The bletilla striata extract is prepared by the following method:
(1) pulverizing dried rhizoma Bletillae, adding ethanol with volume fraction of 50% 18 times of rhizoma Bletillae, and extracting at 80 deg.C for 80 min; then filtering to obtain an extracting solution.
(2) Adjusting pH of the obtained extractive solution to 5, adding 6% active carbon into the extractive solution, stirring at room temperature for 40min, and filtering to obtain filtrate.
(3) Concentrating the filtrate under reduced pressure to obtain concentrated solution, loading the concentrated solution into a chromatographic column with stationary phase of polyamide resin and eluent of 70% ethanol by mass fraction, collecting eluent, filtering the eluent with 0.45 μm filter membrane, concentrating the filtrate under reduced pressure, and removing solvent to obtain rhizoma bletilla extract.
Example 3:
a probiotic compound cosmetic for balancing and repairing skin comprises active substance and cosmetic basic substance. The mass ratio of the active substance to the cosmetic basic substance is 1: 100.
the active substance comprises the following components in percentage by weight: 25% of secondary fission yeast fermentation product filtrate, 13% of hyaluronic acid composition, 6% of resveratrol, 15% of chicory stem extract, 3% of bletilla striata extract and the balance of lactobacillus/mung bean seed extract fermentation product filtrate. The hyaluronic acid composition comprises the following components in percentage by weight: 19% of sodium hyaluronate cross-linked polymer, 28% of sodium hyaluronate, 16% of acetylated sodium hyaluronate and the balance of hydrolyzed sodium hyaluronate.
The cosmetic basic substance comprises the following components in percentage by weight: 8% of absolute ethyl alcohol, 2% of 1, 3-butanediol, 3% of glycerol, 0.06% of menthol, 0.2% of allantoin, 0.08% of citric acid and the balance of water.
The chicory stem extract is prepared by the following method:
(1) taking fresh chicory stems as raw materials, pulverizing, adding ethanol with volume fraction of 65% in an amount which is 14 times that of the chicory stems, and extracting at 65 ℃ for 70 min; then filtering to obtain an extracting solution.
(2) Adjusting pH of the obtained extractive solution to 5, adding 5% of active carbon into the extractive solution, stirring at room temperature for 50min, and filtering to obtain filtrate.
(3) Concentrating the filtrate under reduced pressure to obtain concentrated solution, loading the concentrated solution into a chromatographic column by a wet method, collecting eluent, filtering the eluent by using a 0.45 mu m filter membrane, concentrating the obtained filtrate under reduced pressure, and removing the solvent to obtain the extract of the stem of the chicory.
The bletilla striata extract is prepared by the following method:
(1) pulverizing dried rhizoma Bletillae, adding 60% ethanol 20 times the volume of rhizoma Bletillae, and extracting at 80 deg.C for 60 min; then filtering to obtain an extracting solution.
(2) Adjusting pH of the obtained extractive solution to 5.5, adding 5.5% active carbon into the extractive solution, stirring at room temperature for 50min, and filtering to obtain filtrate.
(3) Concentrating the filtrate under reduced pressure to obtain concentrated solution, loading the concentrated solution into a chromatographic column with stationary phase of polyamide resin and eluent of 60% ethanol by mass fraction, collecting eluent, filtering the eluent with 0.45 μm filter membrane, concentrating the filtrate under reduced pressure, and removing solvent to obtain rhizoma bletilla extract.
Example 4:
a probiotic compound cosmetic for balancing and repairing skin comprises active substance and cosmetic basic substance. The mass ratio of the active substance to the cosmetic basic substance is 1: 80.
the active substance comprises the following components in percentage by weight: 32% of a secondary fission yeast fermentation product filtrate, 12% of a hyaluronic acid composition, 7% of resveratrol, 15% of a chicory stem extract, 4% of a bletilla striata extract and the balance of a lactic acid bacteria/mung bean seed extract fermentation product filtrate. The hyaluronic acid composition comprises the following components in percentage by weight: 20% of sodium hyaluronate cross-linked polymer, 25% of sodium hyaluronate, 23% of acetylated sodium hyaluronate and the balance of hydrolyzed sodium hyaluronate.
The cosmetic basic substance comprises the following components in percentage by weight: 8% of absolute ethyl alcohol, 3% of 1, 3-butanediol, 5% of glycerol, 0.06% of menthol, 0.1% of allantoin, 0.03% of citric acid and the balance of water.
The preparation method of the chicory stem extract and the bletilla striata extract is the same as that in example 1.
Example 5:
a probiotic compound cosmetic for balancing and repairing skin comprises active substance and cosmetic basic substance. The mass ratio of the active substance to the cosmetic basic substance is 1: 80.
the active substance comprises the following components in percentage by weight: 26% of a secondary fission yeast fermentation product filtrate, 16% of a hyaluronic acid composition, 8% of resveratrol, 15% of a chicory stem extract, 3% of a bletilla striata extract and the balance of a lactic acid bacteria/mung bean seed extract fermentation product filtrate. The hyaluronic acid composition comprises the following components in percentage by weight: 18% of sodium hyaluronate cross-linked polymer, 20% of sodium hyaluronate, 16% of acetylated sodium hyaluronate and the balance of hydrolyzed sodium hyaluronate.
The cosmetic basic substance comprises the following components in percentage by weight: 5% of absolute ethyl alcohol, 2% of 1, 3-butanediol, 3% of glycerol, 0.02% of menthol, 0.2% of allantoin, 0.08% of citric acid and the balance of water.
The preparation method of the chicory stem extract and the bletilla striata extract is the same as that in example 1.
Example 6:
a probiotic compound cosmetic for balancing and repairing skin comprises active substance and cosmetic basic substance. The mass ratio of the active substance to the cosmetic basic substance is 1: 60.
the active substance comprises the following components in percentage by weight: 32% of a secondary fission yeast fermentation product filtrate, 15% of a hyaluronic acid composition, 5% of resveratrol, 10% of a chicory stem extract, 6% of a bletilla striata extract and the balance of a lactic acid bacteria/mung bean seed extract fermentation product filtrate. The hyaluronic acid composition comprises the following components in percentage by weight: 25% of sodium hyaluronate cross-linked polymer, 28% of sodium hyaluronate, 20% of acetylated sodium hyaluronate and the balance of hydrolyzed sodium hyaluronate.
The cosmetic basic substance comprises the following components in percentage by weight: 4% of absolute ethyl alcohol, 4% of 1, 3-butanediol, 4% of glycerol, 0.04% of menthol, 0.3% of allantoin, 0.05% of citric acid and the balance of water.
The preparation method of the chicory stem extract and the bletilla striata extract is the same as that in example 1.
The preparation method of the probiotic compound cosmetic for balanced skin repair in the above examples 1 to 6 comprises the following steps:
(1) weighing the secondary fission yeast fermentation product filtrate, the hyaluronic acid composition, the resveratrol, the chicory stem extract, the bletilla striata extract and the lactobacillus/mung bean seed extract fermentation product filtrate according to the proportion, and uniformly mixing the raw materials to obtain an active substance;
(2) weighing anhydrous ethanol, 1, 3-butanediol, glycerol, menthol, allantoin, citric acid and water in proportion, and mixing the above raw materials uniformly to obtain cosmetic basic substance;
(3) adding the active substance into cosmetic basic substance in proportion, and stirring to obtain cosmetic, which is a toner.
And (3) performance testing:
300 women of 20-42 years old are selected as trial objects. The test subjects had healthy skin and no history of skin allergy. 300 trial subjects were randomly divided into 6 groups of 50 subjects each.
The cosmetics of examples 1 to 6 were used in experimental groups 1 to 6, respectively. The using method comprises the following steps: after the trial object cleans the face, the cosmetic toner is uniformly smeared on the face, gently patted until the cosmetic toner is completely absorbed, and is used once in the morning and at night every day for 50 days continuously. The cosmetics were then scored for skin freshness, wrinkle resistance, and water smoothness. The total using effect of each item is 5 points. The average score of each item is as follows. The results are shown in Table 1.
Table 1:
| item | Refreshing property | Resistance to wrinkle | Water lubricity and smoothness |
| Example 1 | 5 | 4.5 | 4.7 |
| Example 2 | 5 | 4.3 | 4.6 |
| Example 3 | 5 | 4.3 | 4.5 |
| Example 4 | 5 | 4.5 | 4.5 |
| Example 5 | 5 | 4.4 | 4.7 |
| Example 6 | 5 | 4.6 | 4.7 |
The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (7)
1. The probiotic compound cosmetic for balancing and repairing the skin is characterized by comprising an active substance and a cosmetic basic substance, wherein the active substance comprises the following components in percentage by weight: 15-32% of a secondary fission yeast fermentation product filtrate, 12-16% of a hyaluronic acid composition, 5-8% of resveratrol, 10-15% of a chicory stem extract, 3-6% of a bletilla striata extract and the balance of a lactic acid bacteria/mung bean seed extract fermentation product filtrate.
2. The probiotic compound cosmetic for balanced skin repair according to claim 1, characterized in that the hyaluronic acid composition consists of the following components in percentage by weight: 18-25% of sodium hyaluronate cross-linked polymer, 20-28% of sodium hyaluronate, 16-23% of acetylated sodium hyaluronate and the balance of hydrolyzed sodium hyaluronate.
3. The balanced skin-repairing probiotic compound cosmetic product according to claim 1, characterized in that said chicory stem extract is prepared by the following method:
(1) pulverizing fresh herba Cichorii stem, adding 60-70% ethanol 13-15 times the volume of herba Cichorii stem, and extracting at 55-65 deg.C for 70-100 min; then filtering to obtain an extracting solution;
(2) adjusting pH of the obtained extractive solution to 5-6, adding 3-5% of active carbon into the extractive solution, stirring at room temperature for 40-50min, and filtering to obtain filtrate;
(3) concentrating the filtrate under reduced pressure to obtain concentrated solution, loading the concentrated solution into a chromatographic column by a wet method, collecting eluent, filtering the eluent by using a 0.45 mu m filter membrane, concentrating the obtained filtrate under reduced pressure, and removing the solvent to obtain the extract of the chicory stem.
4. The probiotic compound cosmetic for balanced skin repair according to claim 1, wherein the bletilla striata extract is prepared by the following method:
(1) pulverizing dried rhizoma Bletillae, adding ethanol with volume fraction of 50-60% 18-23 times of rhizoma Bletillae, and extracting at 70-80 deg.C for 60-80 min; then filtering to obtain an extracting solution;
(2) adjusting pH of the obtained extractive solution to 5-6, adding 5-6% of active carbon into the extractive solution, stirring at room temperature for 40-50min, and filtering to obtain filtrate;
(3) concentrating the filtrate under reduced pressure to obtain concentrated solution, loading the concentrated solution into a chromatographic column with stationary phase of polyamide resin and eluent of 60-70% ethanol by mass fraction, collecting eluent, filtering the eluent with 0.45 μm filter membrane, concentrating the filtrate under reduced pressure, and removing solvent to obtain rhizoma bletilla extract.
5. The probiotic compound cosmetic for balanced repair of skin according to claim 1, characterized in that the cosmetic base consists of the following ingredients in percentage by weight: 4-8% of absolute ethyl alcohol, 2-4% of 1, 3-butanediol, 3-5% of glycerol, 0.02-0.06% of menthol, 0.1-0.3% of allantoin, 0.03-0.08% of citric acid and the balance of water.
6. The probiotic compound cosmetic for balanced repair of skin according to claim 5, wherein the mass ratio of the active substance to the cosmetic basic substance is 1: 60-100.
7. The method for preparing the probiotic compound cosmetic for balanced skin repair according to claim 6, characterized by comprising the following steps:
(1) weighing the secondary fission yeast fermentation product filtrate, the hyaluronic acid composition, the resveratrol, the chicory stem extract, the bletilla striata extract and the lactobacillus/mung bean seed extract fermentation product filtrate according to the proportion, and uniformly mixing the raw materials to obtain an active substance;
(2) weighing anhydrous ethanol, 1, 3-butanediol, glycerol, menthol, allantoin, citric acid and water in proportion, and mixing the above raw materials uniformly to obtain cosmetic basic substance;
(3) adding the active substances into cosmetic basic substances in proportion, and stirring well to obtain the final product.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112870138A (en) * | 2021-01-26 | 2021-06-01 | 广州华厦生物制药有限公司 | Vegetable protein repair milk |
| CN113018199A (en) * | 2020-12-16 | 2021-06-25 | 深圳市景光生物科技有限公司 | Multipurpose ice film for repairing epidermis and preparation method thereof |
| CN113318062A (en) * | 2021-06-22 | 2021-08-31 | 杭州友丽医疗科技(集团)有限公司 | Skin barrier repairing composition, skin barrier repairing liquid and preparation method thereof |
| WO2023104843A1 (en) | 2021-12-09 | 2023-06-15 | Beiersdorf Ag | Topical preparation for enhancing skin condition |
| CN116687788A (en) * | 2023-07-14 | 2023-09-05 | 广东真丽斯化妆品有限公司 | Compound for promoting skin microecological balance by adding active peptide, and preparation method and application thereof |
-
2020
- 2020-07-27 CN CN202010731322.9A patent/CN111671708A/en active Pending
Non-Patent Citations (2)
| Title |
|---|
| 广东真丽斯化妆品有限公司: ""真丽斯益生菌平衡修护水"", 《国产非特殊用途化妆品备案信息服务平台》 * |
| 王建新: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113018199A (en) * | 2020-12-16 | 2021-06-25 | 深圳市景光生物科技有限公司 | Multipurpose ice film for repairing epidermis and preparation method thereof |
| CN112870138A (en) * | 2021-01-26 | 2021-06-01 | 广州华厦生物制药有限公司 | Vegetable protein repair milk |
| CN113318062A (en) * | 2021-06-22 | 2021-08-31 | 杭州友丽医疗科技(集团)有限公司 | Skin barrier repairing composition, skin barrier repairing liquid and preparation method thereof |
| CN113318062B (en) * | 2021-06-22 | 2022-04-12 | 杭州友丽医疗科技(集团)有限公司 | Skin barrier repairing composition, skin barrier repairing liquid and preparation method thereof |
| WO2023104843A1 (en) | 2021-12-09 | 2023-06-15 | Beiersdorf Ag | Topical preparation for enhancing skin condition |
| CN116687788A (en) * | 2023-07-14 | 2023-09-05 | 广东真丽斯化妆品有限公司 | Compound for promoting skin microecological balance by adding active peptide, and preparation method and application thereof |
| CN116687788B (en) * | 2023-07-14 | 2024-05-24 | 广东真丽斯化妆品有限公司 | Compound for promoting skin microecological balance by adding active peptide, and preparation method and application thereof |
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