CN111991287A

CN111991287A - High-moisturizing face cream

Info

Publication number: CN111991287A
Application number: CN202010886045.9A
Authority: CN
Inventors: 张永梅; 许兰英
Original assignee: Individual
Current assignee: Tongfu Group China Co ltd
Priority date: 2020-08-28
Filing date: 2020-08-28
Publication date: 2020-11-27
Anticipated expiration: 2040-08-28
Also published as: CN111991287B

Abstract

The invention relates to the technical field of cosmetics, in particular to a high-moisturizing cream which comprises active substances and a cream substrate, wherein the active substances comprise the following components in percentage by total weight of the high-moisturizing cream: 0.5-2 wt% of goldfish algae extract, 1-3 wt% of bonesetting extract, 0.03-0.1 wt% of gamma-polyglutamic acid and 0.2-1.5 wt% of fungal polysaccharide. The hornworts extract can enhance the water retention and humidity of the skin and dynamically adjust the water-oil balance in the skin; the gamma-polyglutamic acid can form a smooth, elastic and self-moisturizing soft film on the surface of the skin; the fungal polysaccharide can penetrate deep into the skin, improve the skin activity, promote the absorption of the skin on nutrient substances and delay the skin aging, and in addition, the fungal polysaccharide also has strong water absorption and moisture retention effects, enhances the skin elasticity, forms a moisture retention barrier on the skin surface layer and achieves the effect of long-term moisture retention; by matching the four substances, the effects of moisturizing the deep layer of the skin and keeping moisture for a long time can be achieved.

Description

High-moisturizing face cream

Technical Field

The invention relates to the technical field of cosmetics, and particularly relates to a high-moisturizing face cream.

Background

In modern society, the temperature change and pressure caused by air conditioning, environmental pollution and season change, skin aging, metabolism slowing and other factors can cause skin moisture loss, so that the skin is rough, dull, dry and wrinkled, and various skin problems are caused. Skin problems caused by water deficit are by no means as simple as dryness, and almost every skin problem is associated with moisture replenishment and maintenance. Moisture is the first essential factor for beautifying skin, and whitening, sun protection, oil control and the like are all completed on the basis of moisturizing. Skin problems of any season, age, skin type are perfect in water soothing and moisturizing. Therefore, the moisturizing work of the skin is very important.

The face cream is a repairing component containing a plurality of anti-aging, moisturizing, nourishing and the like, has different efficacies, and has obvious effects of each efficacy. The moisturizing cream is one of the moisturizing creams, and the principle of the moisturizing cream is that the moisturizing cream is very high in water content, is easy to uniformly spread and quickly permeates into the epidermis of the skin, so that components for moisturizing the skin can be easily retained and are not easy to evaporate, and a certain water content of the skin is maintained, so that the purpose of moisturizing is achieved, the moisture can easily permeate into the cuticle of the epidermis after the moisturizing cream is spread, the skin becomes soft, and the skin is naturally bright and elastic.

At present, hyaluronic acid with the most moisturizing capability is added into face cream to moisturize the face, but the moisturizing capability of hyaluronic acid still cannot meet the requirements of most people.

Disclosure of Invention

The invention aims to overcome the problem of limited moisturizing capability of the face cream in the prior art, and provides a high-moisturizing face cream.

In order to achieve the above object, an aspect of the present invention provides a high moisturizing cream comprising an active substance and a cream base, the active substance comprising, based on the total amount of the high moisturizing cream: 0.5-2 wt% of goldfish algae extract, 1-3 wt% of bonesetting extract, 0.03-0.1 wt% of gamma-polyglutamic acid and 0.2-1.5 wt% of fungal polysaccharide.

The inventor finds that the goldfish algae extract can enhance the water retention and humidity of the skin, dynamically adjust the water-oil balance in the skin and enable the skin to be more water-moist, has a good repairing effect, has good repairing capability and can improve subcutaneous damaged tissues; the gamma-polyglutamic acid can form a smooth, elastic and self-moisturizing soft film on the surface of the skin; the fungal polysaccharide can penetrate deep into the skin, improve the skin activity, promote the absorption of the skin on nutrient substances and delay the skin aging, and in addition, the fungal polysaccharide also has strong water absorption and moisture retention effects, enhances the skin elasticity, forms a moisture retention barrier on the skin surface layer and achieves the effect of long-term moisture retention; by matching the four substances, the effects of moisturizing the deep layer of the skin and keeping moisture for a long time can be achieved.

In order to further improve the moisturizing effect of the high moisturizing cream, the active substances preferably comprise: 0.8-1.2 wt% of Goldfish algae extract, 1.2-2.5 wt% of Kalanchoe extract, 0.06-0.08 wt% of gamma-polyglutamic acid and 0.5-1 wt% of fungal polysaccharide.

In order to further improve the moisturizing effect of the high-moisturizing cream, under the preferable conditions, the weight ratio of the goldfish algae extract to the bonesetting extract to the fungal polysaccharide is 1:0.8-3.5: 0.15-1.6; further preferably, the weight ratio of the goldfish algae extract to the bonesetting extract to the fungal polysaccharide is 1: 1-2: 0.6-1.

In order to further improve the moisturizing effect of the high-moisturizing cream, the fungus polysaccharide is at least one selected from tremella polysaccharide, ganoderma lucidum polysaccharide, tuber indicum, bolete polysaccharide, needle mushroom polysaccharide, lentinan, morchella polysaccharide, dictyophora indusiata polysaccharide, hericium erinaceus polysaccharide and tricholoma matsutake polysaccharide under the preferable conditions; further preferably, the fungal polysaccharide comprises, based on the total amount of the fungal polysaccharide: 5-10 parts of tremella polysaccharide, 1-5 parts of ganoderma lucidum polysaccharide, 0-3 parts of Indian truffle, 3-8 parts of boletus polysaccharide, 5-9 parts of flammulina velutipes polysaccharide, 1-6 parts of lentinan, 0-5 parts of morchella polysaccharide, 0-7 parts of dictyophora indusiata polysaccharide, 2-8 parts of hericium erinaceus polysaccharide and 1-10 parts of tricholoma matsutake polysaccharide.

In order to further improve the moisturizing effect of the cream, the active substance preferably further comprises: 1-5 wt% of fibroin, 0.1-0.8 wt% of ceramide, 0.3-1.5 wt% of transdermal peptide EFG, 0.1-2.8 wt% of sodium alginate, 5-15 wt% of sodium hyaluronate and 0.2-0.5 wt% of squalane.

The fibroin can form a compact protein film on the face, so that active ingredients in the moisturizing cream are sealed and locked in the skin, the loss of nutrients is avoided, and the effect of long-acting water replenishing is achieved.

Further preferably, the molecular weight of the sodium hyaluronate is 2-10 Kd.

According to the invention, the cream base further comprises at least one of activated carbon, plant essential oil, skin repair agent, surfactant, essence, emulsifier, antioxidant, preservative, sunscreen agent, chelating agent, thickener, humectant.

Wherein the plant essential oil is at least one selected from rose essential oil, camellia essential oil, lemon essential oil, lavender essential oil, calendula oil and geranium essential oil.

In order to improve the repair ability of the high moisturizing cream, it is preferable that the skin repair agent is at least one selected from the group consisting of glycine, alanine, valine, isoleucine, leucine, proline, arginine, aspartic acid, glutamic acid, L-threonine, citric acid, and betaine.

The emulsifier may be known to those skilled in the art, and for example, the emulsifier may be at least one of polyglyceryl-6 distearate, PEG-20 behenyl, cetearyl glucoside, polyglyceryl-3 methyl glucose distearate, cetearyl olive oleate, polysorbate-20, glyceryl stearate, PEG-100 stearate, cocoyl glucoside, polyacrylamide, C13-14 isoparaffin, laureth-7, sodium acrylate/sodium acryloyldimethyl taurate copolymer, polysorbate-80, and sorbitan olive oleate, and the emulsifier may be added in an amount of 1 to 2 wt% based on the total amount of the high moisturizing cream.

The preservative may be known to those skilled in the art, and for example, the preservative may be at least one of methyl hydroxybenzoate, propyl hydroxybenzoate, phenoxyethanol, benzyl alcohol, sodium benzoate, potassium sorbate, anisic acid, and sodium acetolactate, and may be added in an amount of 0.1-0.5 wt% based on the total weight of the high moisturizing cream.

The chelating agent may be known to those skilled in the art, for example the chelating agent may be disodium EDTA and/or tetrasodium EDTA; the addition amount of the chelating agent is 0.02-0.06 wt% of the total amount of the high-moisturizing cream.

The thickener may be known to those skilled in the art, and for example, may be at least one selected from the group consisting of cetostearyl alcohol, beeswax, stearic acid, carbomer, xanthan gum, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, acrylic acid/C10-30 alkanol acrylate crosspolymer, ammonium acryloyldimethyl taurate/VP copolymer, in an amount of 0.5-2.5 wt% based on the total amount of the high moisturizing cream.

The humectant can be known by those skilled in the art, and can be at least one of polyethylene glycol, polypropylene glycol, butanediol, propylene glycol, glycerol, hexanediol, xylitol and sorbitol, and the like, and the amount of the humectant is 2-10 wt% of the total weight of the high moisturizing cream.

Through the technical scheme, the invention has the following technical effects:

the Goldfish algae extract can enhance the water retention and humidity of the skin, dynamically adjust the water-oil balance in the skin and make the skin more water-wet, has good repairing effect, has good repairing capability and can improve subcutaneous damaged tissues; the gamma-polyglutamic acid can form a smooth, elastic and self-moisturizing soft film on the surface of the skin; the fungal polysaccharide can penetrate deep into the skin, improve the skin activity, promote the absorption of the skin on nutrient substances and delay the skin aging, and in addition, the fungal polysaccharide also has strong water absorption and moisture retention effects, enhances the skin elasticity, forms a moisture retention barrier on the skin surface layer and achieves the effect of long-term moisture retention; by matching the four substances, the effects of moisturizing the deep layer of the skin and keeping moisture for a long time can be achieved.

Detailed Description

The endpoints of the ranges and any values disclosed herein are not limited to the precise range or value, and such ranges or values should be understood to encompass values close to those ranges or values. For ranges of values, between the endpoints of each of the ranges and the individual points, and between the individual points may be combined with each other to give one or more new ranges of values, and these ranges of values should be considered as specifically disclosed herein.

The present invention will be described in detail below by way of examples.

Sodium hyaluronate was purchased from Sai Asahi Total Biotechnology Co., Ltd, cat # 9067-32-7.

The golden fish algae extract is extracted from golden fish algae by a supercritical carbon dioxide method, and the process conditions of the supercritical carbon dioxide method are as follows: the extraction pressure is 30Mpa, the temperature is 60 ℃, the flow rate of carbon dioxide is 1.5L/min, the extraction time is 60min, the separation I pressure is 5MPa, the temperature is 60 ℃, the separation II pressure is 5MPa, the temperature is 60 ℃, and the entrainer is 95% ethanol with the amount of 1 time.

The white bonesetting extract is extracted from white bonesetting by adopting a microwave extraction method, and the process conditions of the microwave extraction method are as follows: taking ethanol as an extraction solvent, wherein the liquid-material ratio is 1:6, the microwave power is 500W, the extraction time is 30min, and further purifying the microwave extraction product (the mobile phase is acetic acid acetonitrile) by adopting a gradient elution HPLC method to obtain the extract of the bonesetting.

In the following examples, the composition of fungal polysaccharide a is: 8 parts of tremella polysaccharide, 2 parts of ganoderma polysaccharide, 1 part of Indian truffle, 8 parts of boletus polysaccharide, 6 parts of flammulina velutipes polysaccharide, 1 part of lentinan, 1 part of morchella polysaccharide, 7 parts of dictyophora indusiata polysaccharide, 6 parts of hericium erinaceus polysaccharide and 2 parts of tricholoma matsutake polysaccharide.

The composition of the fungal polysaccharide B is as follows: 5 parts of tremella polysaccharide, 1 part of ganoderma polysaccharide, 1 part of Indian truffle, 3 parts of boletus polysaccharide, 5 parts of needle mushroom polysaccharide, 2 parts of lentinan, 3 parts of morchella polysaccharide, 3 parts of bamboo fungus polysaccharide, 8 parts of hericium erinaceus polysaccharide and 1 part of tricholoma matsutake polysaccharide.

The composition of fungal polysaccharide C was: 10 parts of tremella polysaccharide, 5 parts of ganoderma lucidum polysaccharide, 3 parts of Indian truffle, 5 parts of boletus polysaccharide, 9 parts of needle mushroom polysaccharide, 6 parts of lentinan, 5 parts of morchella polysaccharide, 2 parts of dictyophora indusiata polysaccharide, 2 parts of hericium erinaceus polysaccharide and 10 parts of tricholoma matsutake polysaccharide.

Examples 1 to 5

The contents of the materials in the creams of examples 1 to 5 are shown in Table 1, and the high moisturizing cream performances provided by examples 1 to 5 are shown in Table 2.

TABLE 1

Example 6

The process of example 1 was followed except that: the high moisturizing cream performance provided in this example is shown in table 2 using fungal polysaccharide B instead of fungal polysaccharide a.

Example 7

The process of example 1 was followed except that: the high moisturizing cream performance provided in this example is shown in table 2 using fungal polysaccharide C instead of fungal polysaccharide a.

Example 8

The process of example 1 was followed except that: the flammulina velutipes polysaccharide is adopted to replace the fungal polysaccharide A, and the performance of the high-moisturizing cream provided by the embodiment is shown in Table 2.

Comparative example 1

The process of example 1 was followed except that: without the goldfish extract, this example provides high moisturizing cream performance as shown in table 2.

Comparative example 2

The process of example 1 was followed except that: without the extract of Kadsura coccinea, this example provides a high moisturizing cream performance as shown in Table 2.

Comparative example 3

The process of example 1 was followed except that: without gamma-polyglutamic acid, this example provides high moisturizing cream performance as shown in table 2.

Comparative example 4

The process of example 1 was followed except that: without fungal polysaccharide a, this example provides high moisturizing cream performance as shown in table 2.

Blank example

The process of example 1 was followed except that: the high moisturizing cream provided by the example, without the goldfish algae extract, the bonesetting extract, the gamma-polyglutamic acid and the fungal polysaccharide A, is shown in Table 2.

Test example

130 healthy female volunteers of 20-35 years old without allergic history were selected and divided into 13 groups of 10 persons each, and the high moisturizing creams prepared in examples 1-8, comparative examples 1-4 and blank example were tested, respectively. All subjects had signed an informed consent.

When in test, the left forearm of a subject is taken as a tested part, a face cream sample is smeared for 1 time in the morning and evening every day, the skin reaction after 24 hours is observed by lightly massaging the left forearm by fingers until the skin is completely absorbed and taking the right forearm as a blank control.

As a result: after detection, the product has good smell and stability, all subjects have no abnormal phenomena such as erythema and the like, and the observation is continued for 3-4d, so that the result still has no reaction, and the cream prepared by the technical scheme is safe.

During testing, the inner area of the left forearm of a subject is used as a tested part, the tested part is cleaned by clean water before testing and is stabilized for 30min before testing, the testing temperature is 20-25 ℃, the relative humidity is 50-60%, cream is smeared on the tested part and is massaged until absorption, the percentage content of water of the tested part is measured by an intelligent water tester before and after use for 0h, 2h, 4h and 8h, the test is repeated for 5 times every time, the average value is obtained, and the experimental result is shown in table 2.

TABLE 2

	Before use/%)	0h/％	2h/％	4h/％	8h/％
						Example 1	32.6±1.1	77.5±1.9	72.3±3.6	69.5±2.6	58.3±1.9
Example 2	31.8±0.8	76.3±2.8	71.0±3.1	68.4±3.2	54.9±2.6
						Example 3	29.5±1.1	75.1±3.7	69.8±3.8	65.9±3.5	58.7±1.9
Example 4	28.6±1.2	73.2±3.5	68.7±2.8	61.8±2.7	54.9±2.6
						Example 5	30.5±0.9	72.1±2.8	65.4±2.9	60.4±2.5	55.4±3.4
Example 6	32.1±1.4	69.3±1.9	60.3±3.0	58.4±2.4	49.3±2.5
						Example 7	29.5±1.5	68.2±2.7	60.7±3.4	57.3±2.9	48.5±2.8
Example 8	30.8±1.1	68.7±3.6	59.8±2.6	54.1±2.4	45.9±2.9
						Comparative example 1	31.4±0.9	65.3±2.8	52.1±2.5	49.2±2.8	40.8±3.1
Comparative example 2	32.5±0.8	64.7±4.1	53.7±3.7	48.3±3.4	37.8±3.2
						Comparative example 3	30.4±1.3	60.2±3.2	49.3±1.8	46.3±2.9	38.7±2.7
Comparative example 4	31.7±2.5	63.9±2.3	56.7±2.6	41.3±2.7	36.4±2.5
						Blank spaceExample (b)	31.5±1.2	55.4±3.6	45.7±2.4	36.6±2.6	32.2±2.6

The preferred embodiments of the present invention have been described above in detail, but the present invention is not limited thereto. Within the scope of the technical idea of the invention, many simple modifications can be made to the technical solution of the invention, including combinations of various technical features in any other suitable way, and these simple modifications and combinations should also be regarded as the disclosure of the invention, and all fall within the scope of the invention.

Claims

1. A high moisturizing cream comprising an active and a cream base, wherein the active comprises, based on the total amount of the high moisturizing cream: 0.5-2 wt% of goldfish algae extract, 1-3 wt% of bonesetting extract, 0.03-0.1 wt% of gamma-polyglutamic acid and 0.2-1.5 wt% of fungal polysaccharide.

2. The high moisturizing cream of claim 1, wherein the active comprises: 0.8-1.2 wt% of Goldfish algae extract, 1.2-2.5 wt% of Kalanchoe extract, 0.06-0.08 wt% of gamma-polyglutamic acid and 0.5-1 wt% of fungal polysaccharide.

3. The high moisturizing cream according to claim 1 or 2, wherein the weight ratio of the goldfish algae extract, the bonesetting extract and the fungal polysaccharide is 1:0.8-3.5: 0.15-1.6.

4. The cream as claimed in claim 3, wherein the weight ratio of the Goldfish algae extract, the Kalanchoe extract and the fungal polysaccharide is 1: 1-2: 0.6-1.

5. The cream according to any one of claims 1 to 3, wherein the fungal polysaccharide is at least one selected from the group consisting of Tremella polysaccharides, Ganoderma polysaccharides, Tuber indicum, Boletus edulis polysaccharides, Flammulina velutipes polysaccharides, lentinan, Morchella esculenta polysaccharides, Dictyophora indusiata polysaccharides, Hericium erinaceus polysaccharides, and Tricholoma matsutake polysaccharides.

6. The high moisturizing cream of claim 5, wherein the fungal polysaccharide comprises, based on the total amount of the fungal polysaccharide: 5-10 parts of tremella polysaccharide, 1-5 parts of ganoderma lucidum polysaccharide, 0-3 parts of Indian truffle, 3-8 parts of boletus polysaccharide, 5-9 parts of flammulina velutipes polysaccharide, 1-6 parts of lentinan, 0-5 parts of morchella polysaccharide, 0-7 parts of dictyophora indusiata polysaccharide, 2-8 parts of hericium erinaceus polysaccharide and 1-10 parts of tricholoma matsutake polysaccharide.

7. The cream as claimed in claim 6, wherein the weight ratio of the tremella polysaccharide, the ganoderma lucidum polysaccharide, the morchella polysaccharide, the bamboo fungus polysaccharide and the hericium erinaceus polysaccharide in the fungus polysaccharide is 1:0.1-0.5:0.2-0.5:0.2-1.4: 0.2-1.2.

8. The high moisturizing cream of any one of claims 1-7, wherein the active further comprises: 1-5 wt% of fibroin, 0.1-0.8 wt% of ceramide, 0.3-1.5 wt% of transdermal peptide EFG, 0.1-2.8 wt% of sodium alginate, 5-15 wt% of sodium hyaluronate and 0.2-0.5 wt% of squalane.

9. The high moisturizing cream of claim 8, wherein the sodium hyaluronate has a molecular weight of 2-10 Kd.

10. The high moisturizing cream of any one of claims 1-9, wherein the cream base further comprises at least one of activated carbon, plant essential oils, skin rejuvenating agents, surfactants, fragrances, emulsifiers, antioxidants, preservatives, sunscreens, chelating agents, thickeners, humectants, gelling agents, and foam boosters.