CN111759887A - Rhinitis ointment and preparation method thereof - Google Patents
Rhinitis ointment and preparation method thereof Download PDFInfo
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- CN111759887A CN111759887A CN202010841595.9A CN202010841595A CN111759887A CN 111759887 A CN111759887 A CN 111759887A CN 202010841595 A CN202010841595 A CN 202010841595A CN 111759887 A CN111759887 A CN 111759887A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
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- A61K2236/30—Extraction of the material
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- Bioinformatics & Cheminformatics (AREA)
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Abstract
The invention discloses rhinitis ointment and a preparation method thereof, and the preparation raw materials of the rhinitis ointment comprise the following raw materials in parts by weight: 5-10 parts of tea leaves, 10-15 parts of basil leaves, 10-15 parts of rosemary leaves and 5-10 parts of eucalyptus leaves; the tea leaves are leaves of melaleuca alternifolia. The invention combines the traditional process with the modern traditional Chinese medicine technology, and the prepared rhinitis ointment has the advantages of good curative effect, clear effect, convenient and simple use, safety and no toxic or side effect. Can be used for treating chronic rhinitis, sinusitis, turbinate swelling, allergic rhinitis, etc., and has effects of ventilating, diminishing inflammation, clearing pathogenic fire, and inhibiting bacteria, and can achieve basic rehabilitation purpose after 7-15 days.
Description
Technical Field
The invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to rhinitis cream and a preparation method thereof.
Background
Rhinitis, an inflammatory disease of the nasal cavity, is inflammation of the mucous membrane of the nasal cavity caused by viruses, bacteria, allergens, various physicochemical factors and certain systemic diseases. The main pathological changes of rhinitis are congestion, swelling, exudation, hyperplasia, atrophy or necrosis of the nasal mucosa.
At present, the following methods are mainly used for treating rhinitis:
1. oral administration of the medicine: the rhinitis tablet is mainly used for treating the primary pathogenic factors of rhinitis, the medicine is different according to different rhinitis, allergic rhinitis needs antiallergic treatment, common rhinitis can take rhinitis tablets, and atrophic rhinitis needs to take vitamin medicines;
2. local nasal drops: the nasal drop is generally mainly used for relieving the symptoms of rhinitis, nasal oil can relieve the dryness of rhinitis sicca, furosemide can relieve nasal obstruction, and hormone nasal drops are helpful for relieving the symptoms of sneezing, clear nasal discharge and the like of allergic rhinitis;
3. and (3) surgical treatment: the operation is mainly used for treating rhinitis which cannot be treated by medicines or has unobvious effect, can solve nasal obstruction, and is suitable for nasal obstruction caused by hypertrophy of nasal turbinates or atrophic rhinitis with extremely dry nasal cavity and the like;
4. laser or microwave therapy.
However, most of the existing treatment methods for rhinitis have the defects of not obvious effect, low cure rate, long treatment time, high treatment cost and the like. Therefore, the search for a drug with good therapeutic effect and low cost for treating rhinitis is a problem to be solved urgently by those skilled in the art.
Disclosure of Invention
In view of the above, the invention aims to provide rhinitis ointment and a preparation method thereof, the rhinitis ointment is prepared from effective components of Chinese herbal medicines, has no toxic or side effect, and has the obvious effects of high cure rate, short treatment course and no relapse.
The purpose of the invention is realized by the following technical scheme:
the rhinitis ointment is prepared from the following raw materials in parts by weight:
the tea leaves are leaves of Melaleuca alternifolia (Maiden & Betche) Cheel);
the raw materials for preparing the rhinitis ointment also comprise 0.5-1 part of beeswax and 1-2 parts of coconut oil.
Preferably, the raw materials for preparing the rhinitis ointment comprise the following raw materials in parts by weight:
the preparation method of the rhinitis ointment comprises the following steps:
firstly, cleaning tea leaves (leaves of melaleuca alternifolia), basil leaves, rosemary leaves and eucalyptus leaves, then freeze-drying, crushing and sieving to obtain powder;
sieving the mixture by a sieve of 150 meshes;
secondly, adding the powder obtained in the first step into an ultrasonic cell crusher, adding water, and carrying out ultrasonic treatment for 30-50 min, wherein the temperature is controlled to be not more than 30 ℃ during treatment;
in the second step, the amount of the water is 2-3 times of the mass of the powder in the first step;
in the second step, ultrasonic treatment is carried out, wherein the power is 1000-1500 w, and the ultrasonic frequency is 19-23 KHz;
thirdly, putting the powder after ultrasonic treatment into a steam distillation device for distillation for at least 4 hours, and after steam condensation, carrying out liquid-liquid separation to obtain mixed essential oil; and mixing the obtained mixed essential oil, beeswax and coconut oil uniformly to obtain the rhinitis ointment.
The application method of the rhinitis ointment comprises the following steps: the inner wall of the nasal cavity is cleaned by dipping a cotton swab with a proper amount of light saline until no secretion exists, 1g of the rhinitis cream is smeared at a position of 0.7cm inside the nasal cavity by using a clean cotton swab, the cotton swab is thrown away, and the nasal wings are lightly pressed to enable the rhinitis cream to be fully absorbed. The Chinese medicinal ointment can relieve dryness and itch after being used for 5 minutes, and patients can sneeze, rhinorrhea and the like, and belongs to the normal toxin expelling phenomenon, and serious patients can use the ointment for multiple times a day.
The application range of the rhinitis ointment of the invention is as follows: can be used for treating rhinitis, sinusitis, acute and chronic rhinitis, allergic rhinitis, seasonal rhinitis, nasal swelling and pain, nasal obstruction and nasal discomfort caused by common cold, and has adjuvant treatment effect on hypertrophy of nasal turbinates and nasal polyp.
In the rhinitis ointment, the tea tree essential oil has broad-spectrum antimicrobial effect, is environment-friendly, mild, natural and fragrant, free of pollution and corrosion, strong in permeability, locally analgesic and bitter, biologically strong in level-swelling capacity, and capable of expelling parasites and killing mites, has peculiar effects of treating acnes and acnes, and has the effects of refreshing and restoring consciousness due to unique fragrant smell.
The efficacy of basil: relieving pain, and greatly improving dysmenorrhea; treating gastroenteropathy, such as abdominal distention, constipation, and nausea of pregnant women; anti-spasm; sterilizing; promoting blood circulation, and is suitable for rehabilitation after illness; has antiaging and acne treating effects, and is effective for compacting skin; refreshing, improving dysfunction, stabilizing mood, and resisting depression.
The efficacy of the rosemary: has strong contraction effect, can tighten loose skin, and can relieve congestion and swelling; can improve dandruff and stimulate hair growth. Is helpful for treating headache, migraine, neuralgia, mental fatigue and neurasthenia, and herba Rosmarini officinalis essential oil has antiseptic and antibacterial effects, and is especially suitable for treating intestinal infection and dysentery, relieving dyspepsia and flatulence, coordinating symptoms of liver discomfort and jaundice, and relieving pain caused by arthritis, rheumatism and gout. For the respiratory system it has a therapeutic effect on cough from asthma, bronchitis, mucositis sinusitis and the segment.
The efficacy of eucalyptus: has obvious effect on skin scald, prevents bacterial breeding and pus accumulation, promotes the construction of new tissues, improves the skin of suppuration, herpes and whelk, and unblocks pores; the symptoms of cut, wound, ulcer and inflammation are all well responded after the eucalyptus essential oil is used. Antiviral effect, most effective against respiratory diseases, and can alleviate inflammation and make nasal mucosa comfortable, such as: common cold, cough, sinusitis, etc.; has effects in relieving fever, reducing body temperature, and refreshing body; can also eliminate body odor and improve migraine; it is also helpful for genitourinary system, and can improve cystitis and diarrhea.
The beeswax has strong permeability to skin as solvent of medicine, and is helpful for medicine permeation to human body and improving drug effect. The function of the coconut oil: antioxidant and softening agent.
Compared with the prior art, the invention has the following advantages and effects:
the invention combines the traditional process with the modern traditional Chinese medicine technology, and the prepared rhinitis ointment has the advantages of good curative effect, clear effect, convenient and simple use, safety and no toxic or side effect. Can be used for treating chronic rhinitis, sinusitis, turbinate swelling, allergic rhinitis, etc., and has effects of ventilating, diminishing inflammation, clearing pathogenic fire, and inhibiting bacteria, and can achieve basic rehabilitation purpose after 7-15 days.
Detailed Description
The present invention will be described in further detail with reference to examples, but the embodiments of the present invention are not limited thereto.
Example 1
The Chinese herbal medicine rhinitis ointment comprises the following raw materials in parts by weight: 5 parts of melaleuca alternifolia leaves, 12 parts of basil leaves, 15 parts of rosemary leaves, 5 parts of eucalyptus leaves, 0.8 part of beewax and 2 parts of coconut oil.
The preparation method of the rhinitis ointment comprises the following specific steps:
firstly, cleaning tea trees (leaves of melaleuca alternifolia), basil leaves, rosemary leaves and eucalyptus leaves, freeze-drying, crushing and sieving by a 150-mesh sieve to obtain powder for later use; secondly, adding the powder obtained in the first step into an ultrasonic cell crusher, adding a proper amount of water (the ratio of the material to the liquid is generally 1: 2-3 g/g), and carrying out ultrasonic treatment (the power is 1000-1500 w, and the ultrasonic frequency is 19-23 KHz) for 30-50 min, wherein the temperature is controlled not to exceed 30 ℃ during treatment; thirdly, putting the powder processed in the second step into a steam distillation device for distillation for 4 hours, and after steam condensation, carrying out liquid-liquid separation to obtain mixed essential oil of tea trees and the like. And fourthly, mixing and heating the mixed essential oil, the beewax and the coconut oil, stirring uniformly, immediately filling into a paste tube, and cooling and shaping to obtain the rhinitis ointment.
Example 2
The Chinese herbal medicine rhinitis ointment comprises the following raw materials in parts by weight: 8 parts of melaleuca alternifolia leaves, 15 parts of basil leaves, 10 parts of rosemary leaves, 7 parts of eucalyptus leaves, 1 part of beeswax and 1 part of coconut oil.
Example 3
The Chinese herbal medicine rhinitis ointment comprises the following raw materials in parts by weight: 10 parts of melaleuca alternifolia leaves, 10 parts of basil leaves, 13 parts of rosemary leaves, 10 parts of eucalyptus leaves, 0.5 part of beewax and 1.5 parts of coconut oil.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.
Claims (7)
1. The rhinitis ointment is characterized in that the preparation raw materials comprise the following raw materials in parts by weight:
the tea leaves are leaves of melaleuca alternifolia.
2. The rhinitis cream according to claim 1, wherein: the raw materials for preparing the rhinitis ointment also comprise 0.5-1 part of beeswax and 1-2 parts of coconut oil.
3. The rhinitis cream according to claim 1, wherein: the rhinitis ointment is prepared from the following raw materials in parts by weight:
4. a process for the preparation of a rhinitis ointment as claimed in any one of claims 1 to 3, which comprises the steps of:
firstly, cleaning tea leaves, basil leaves, rosemary leaves and eucalyptus leaves, then freeze-drying, crushing and sieving to obtain powder;
secondly, adding the powder obtained in the first step into an ultrasonic cell crusher, adding water, and carrying out ultrasonic treatment for 30-50 min, wherein the temperature is controlled to be not more than 30 ℃ during treatment;
thirdly, putting the powder after ultrasonic treatment into a steam distillation device for distillation for at least 4 hours, and after steam condensation, carrying out liquid-liquid separation to obtain mixed essential oil; and mixing the obtained mixed essential oil, beeswax and coconut oil uniformly to obtain the rhinitis ointment.
5. The method of claim 4, wherein: the sieving in the step I is to sieve through a 150-mesh sieve.
6. The method of claim 4, wherein: in the second step, the amount of the water is 2-3 times of the mass of the powder in the first step.
7. The method of claim 4, wherein: and in the second step, performing ultrasonic treatment with the power of 1000-1500 w and the ultrasonic frequency of 19-23 KHz.
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| CN114767753A (en) * | 2022-04-24 | 2022-07-22 | 广州城市职业学院 | Essential oil paste beneficial to respiratory system and preparation method thereof |
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| CN111346161A (en) * | 2020-03-10 | 2020-06-30 | 武冰 | Essential oil composition for treating rhinitis and preparation method thereof |
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