CN112972578A - Ointment for treating psoriasis and preparation method thereof - Google Patents

Ointment for treating psoriasis and preparation method thereof Download PDF

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Publication number
CN112972578A
CN112972578A CN201911276351.4A CN201911276351A CN112972578A CN 112972578 A CN112972578 A CN 112972578A CN 201911276351 A CN201911276351 A CN 201911276351A CN 112972578 A CN112972578 A CN 112972578A
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liniment
parts
aloe
treating psoriasis
psoriasis
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陆欣
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234—Cnidium (snowparsley)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/758—Zanthoxylum, e.g. pricklyash
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

The invention belongs to the technical field of psoriasis treatment, and particularly relates to a liniment for treating psoriasis and a preparation method thereof. The liniment for treating psoriasis is prepared from the following raw materials: rhizoma Ligustici Chuanxiong, Notoginseng radix, fructus Zanthoxyli, fructus Cnidii, folium Artemisiae Argyi, Aloe, trehalose, herba Menthae, alkyl glycoside, osmotic pressure regulator, and plant organic acid. The liniment provided by the invention has the effects of clearing heat, moistening skin, promoting blood circulation and restoring menstrual flow, repairing skin disease injury, activating cell tissue regeneration capacity, and has exact curative effect and quick response; has good treatment effect on psoriasis; and has no irritation to skin and no side effect.

Description

Ointment for treating psoriasis and preparation method thereof
Technical Field
The invention belongs to the technical field of psoriasis treatment, and particularly relates to an ointment for treating psoriasis and a preparation method thereof.
Background
Psoriasis is a common chronic inflammatory skin disease in the dermatology department that is prone to relapse. The early stage is inflammatory red papule, about millet to mung bean in size, and then gradually expands or fuses into brownish red plaque with clear boundary, inflammatory red halo around the plaque, obvious substrate infiltration, and multiple layers of dry grey-white or silvery-white scales on the surface. The scurf and blood stasis can be removed during the attack, the dryness and the itch are difficult to endure, the appearance is affected, and great pain is brought to the mind and the body of a patient. The psoriasis has high morbidity and long course of disease, and seriously harms the physical and mental health of patients.
At present, the treatment of psoriasis is mostly carried out by western medicine. The western medicine for treating psoriasis mainly adopts the medicines for diminishing inflammation, inhibiting cell proliferation and the like, most of the medicines only aim at eliminating skin damage, but can not well control the state of an illness and prevent relapse although the medicines take effect quickly, only treat symptoms but not root causes, have large side effects and are easy to relapse.
Disclosure of Invention
In order to solve the technical problems in the prior art, the invention provides a liniment for treating psoriasis and a preparation method thereof, and the liniment is realized by the following technical scheme:
a liniment for treating psoriasis is prepared from the following raw materials: rhizoma Ligustici Chuanxiong, Notoginseng radix, fructus Zanthoxyli, fructus Cnidii, folium Artemisiae Argyi, Aloe, trehalose, herba Menthae, alkyl glycoside, osmotic pressure regulator, and plant organic acid.
Preferably, the liniment for treating psoriasis is prepared from the following raw materials in parts by weight: 8-12 parts of ligusticum wallichii, 8-12 parts of pseudo-ginseng, 6-8 parts of pepper, 8-12 parts of fructus cnidii, 3-6 parts of wormwood, 8-12 parts of aloe, 2-4 parts of trehalose, 2-4 parts of mint, 0.1-0.2 part of alkyl glycoside, 0.03-0.05 part of osmotic pressure regulator and 0.01-0.02 part of plant organic acid.
Preferably, the osmotic pressure regulator is calcium chloride.
Preferably, the plant organic acid is prepared from tartaric acid and citric acid according to the ratio of 2-3: 1, in terms of mass ratio.
Preferably, the preparation method of the liniment for treating psoriasis comprises the following steps:
(1) pulverizing rhizoma Ligustici Chuanxiong, Notoginseng radix, fructus Zanthoxyli, fructus Cnidii, folium Artemisiae Argyi, and herba Menthae, mixing, adjusting water content to 40-50%, and treating with steam for 30-35 min; cooling to obtain Chinese medicinal powder;
(2) adding the traditional Chinese medicine powder into glutinous rice wine 6-8 times of the weight of the traditional Chinese medicine powder to mix into a mixture, adding 0.06-0.07% of compound bacterial liquid into the mixture, fermenting for 3-4 days at 25-30 ℃, and filtering to obtain glutinous rice wine extracting solution and filter residue;
(3) adding water 10-12 times the weight of the residue into the residue, decocting for 1-1.5 hr, adding acid, stirring, cooling to 40-45 deg.C, maintaining the temperature, stirring, extracting for 25-30min, filtering, and cooling to obtain water extract;
(4) squeezing Aloe to obtain Aloe juice; mixing the glutinous rice wine extractive solution, water extractive solution, Aloe juice, trehalose, alkyl glycoside, and osmotic pressure regulator, homogenizing, and making into liniment.
Preferably, the alcohol content of the glutinous rice wine is 10-15 degrees.
Preferably, the compound bacterial liquid is a compound bacterial liquid obtained by taking aspergillus and saccharomycetes
Preferably, the viable count of the compound bacterial liquid and the aspergillus is 3-5 multiplied by 108cfu/ml, viable count of yeast is 1-2 × 106cfu/ml。
The invention has the beneficial effects that:
rhizoma Ligustici Chuanxiong and Notoginseng radix have blood circulation promoting and dysmenorrhea promoting effects; the Chinese prickly ash, the common cnidium fruit and the wormwood are used in combination to have the effects of disinfection, sterilization and itching relief. Aloe, trehalose, herba Menthae, and alkyl glycoside have effects of clearing heat, caring skin, repairing skin injury, and promoting cell regeneration; meanwhile, the biocompatibility between the liniment and the skin can be improved. The osmotic pressure regulator and the plant organic acid can promote the skin to absorb the effective components in the liniment.
The liniment provided by the invention has the effects of clearing heat, moistening skin, promoting blood circulation and restoring menstrual flow, repairing skin disease injury, activating cell tissue regeneration capacity, and has exact curative effect and quick response; has good treatment effect on psoriasis; and has no irritation to skin and no side effect.
Detailed Description
The technical solution of the present invention is further defined below with reference to the specific embodiments, but the scope of the claims is not limited to the description.
Example 1
The components are as follows: 8kg of ligusticum wallichii, 8kg of pseudo-ginseng, 6kg of pepper, 8kg of fructus cnidii, 3kg of wormwood, 8kg of aloe, 2kg of trehalose, 2kg of mint, 0.1kg of alkyl glycoside, 0.03kg of calcium chloride and 0.01kg of plant organic acid.
The plant organic acid is prepared from tartaric acid and citric acid according to the weight ratio of 2: 1, in terms of mass ratio.
The preparation method of the liniment for treating psoriasis comprises the following steps:
(1) pulverizing rhizoma Ligustici Chuanxiong, Notoginseng radix, fructus Zanthoxyli, fructus Cnidii, folium Artemisiae Argyi, and herba Menthae, mixing, adjusting water content to 40-50%, and treating with steam for 30 min; cooling to obtain Chinese medicinal powder;
(2) adding the traditional Chinese medicine powder into glutinous rice wine with the alcohol content of 10-15 degrees and the mass of 6 times of the traditional Chinese medicine powder to mix into a mixture, adding compound bacterial liquid with the mass of 0.06 percent into the mixture, fermenting for 3 days at the temperature of 25-30 ℃, and filtering to obtain glutinous rice wine extracting solution and filter residue;
(3) adding water 10 times the weight of the residue into the residue, decocting for 1 hr, adding acid, stirring, cooling to 40-45 deg.C, extracting under stirring for 25min, filtering, and cooling to obtain water extractive solution;
(4) squeezing Aloe to obtain Aloe juice; mixing the glutinous rice wine extractive solution, water extractive solution, Aloe juice, trehalose, alkyl glycoside, and osmotic pressure regulator, homogenizing, and making into liniment.
The compound bacteria liquid is prepared from Aspergillus and yeast
The number of viable bacteria of the compound bacterial liquid and the aspergillus is 3-5 multiplied by 108cfu/ml, viable count of yeast is 1-2 × 106cfu/ml。
Example 2
The components are as follows: 10kg of ligusticum wallichii, 10kg of pseudo-ginseng, 7kg of pepper, 10kg of fructus cnidii, 5kg of wormwood, 10kg of aloe, 3kg of trehalose, 3kg of mint, 0.15kg of alkyl glycoside, 0.04kg of calcium chloride and 0.015kg of plant organic acid.
The plant organic acid is prepared from tartaric acid and citric acid according to the weight ratio of 2: 1, in terms of mass ratio.
The preparation method of the liniment for treating psoriasis comprises the following steps:
(1) pulverizing rhizoma Ligustici Chuanxiong, Notoginseng radix, fructus Zanthoxyli, fructus Cnidii, folium Artemisiae Argyi, and herba Menthae, mixing, adjusting water content to 40-50%, and treating with steam for 35 min; cooling to obtain Chinese medicinal powder;
(2) adding the traditional Chinese medicine powder into glutinous rice wine with the alcohol content of 10-15 degrees and the mass of which is 8 times of that of the traditional Chinese medicine powder to mix into a mixture, adding compound bacterial liquid with the mass of 0.065 percent into the mixture, fermenting for 4 days at the temperature of 25-30 ℃, and filtering to obtain glutinous rice wine extracting solution and filter residue;
(3) adding water 10 times the weight of the residue into the residue, decocting for 1 hr, adding acid, stirring, cooling to 40-45 deg.C, extracting under stirring for 28min, filtering, and cooling to obtain water extractive solution;
(4) squeezing Aloe to obtain Aloe juice; mixing the glutinous rice wine extractive solution, water extractive solution, Aloe juice, trehalose, alkyl glycoside, and osmotic pressure regulator, homogenizing, and making into liniment.
The compound bacteria liquid is prepared from Aspergillus and yeast
The number of viable bacteria of the compound bacterial liquid and the aspergillus is 3-5 multiplied by 108cfu/ml, viable count of yeast is 1-2 × 106cfu/ml。
Example 3
The components are as follows: 12kg of ligusticum wallichii, 12kg of pseudo-ginseng, 8kg of pepper, 12kg of fructus cnidii, 6kg of wormwood, 12kg of aloe, 4kg of trehalose, 4kg of mint, 0.2kg of alkyl glycoside, 0.05kg of calcium chloride and 0.02kg of plant organic acid.
The plant organic acid is prepared from tartaric acid and citric acid according to the weight ratio of 3: 1, in terms of mass ratio.
The preparation method of the liniment for treating psoriasis comprises the following steps:
(1) pulverizing rhizoma Ligustici Chuanxiong, Notoginseng radix, fructus Zanthoxyli, fructus Cnidii, folium Artemisiae Argyi, and herba Menthae, mixing, adjusting water content to 40-50%, and treating with steam for 35 min; cooling to obtain Chinese medicinal powder;
(2) adding the traditional Chinese medicine powder into glutinous rice wine with the alcohol content of 10-15 degrees and the mass of which is 8 times of that of the traditional Chinese medicine powder to mix into a mixture, adding compound bacterial liquid with the mass of 0.07 percent into the mixture, fermenting for 4 days at the temperature of 25-30 ℃, and filtering to obtain glutinous rice wine extracting solution and filter residue;
(3) adding 12 times of water into the residue, decocting for 1.5 hr, adding acid, stirring, cooling to 40-45 deg.C, extracting under stirring for 30min, filtering, and cooling to obtain water extractive solution;
(4) squeezing Aloe to obtain Aloe juice; mixing the glutinous rice wine extractive solution, water extractive solution, Aloe juice, trehalose, alkyl glycoside, and osmotic pressure regulator, homogenizing, and making into liniment.
The compound bacteria liquid is prepared from Aspergillus and yeast
The number of viable bacteria of the compound bacterial liquid and the aspergillus is 3-5 multiplied by 108cfu/ml, viable count of yeast is 1-2 × 106cfu/ml。
Test example 1
The liniment prepared by the embodiment of the invention is used for treating 120 cases of psoriasis patients, the attack period is 1 year to 30 years, the liniment is lightly applied to the affected part of the psoriasis for 2 to 3 times a day, one month is a treatment course, the cure rate is 87.50 percent, and the effective rate is 98.33 percent.
It should be noted that the above examples and test examples are only for further illustration and understanding of the technical solutions of the present invention, and are not to be construed as further limitations of the technical solutions of the present invention, and the invention which does not highlight essential features and significant advances made by those skilled in the art still belongs to the protection scope of the present invention.

Claims (8)

1. The liniment for treating psoriasis is characterized by being prepared from the following raw materials: rhizoma Ligustici Chuanxiong, Notoginseng radix, fructus Zanthoxyli, fructus Cnidii, folium Artemisiae Argyi, Aloe, trehalose, herba Menthae, alkyl glycoside, osmotic pressure regulator, and plant organic acid.
2. The liniment for treating psoriasis according to claim 1, which is prepared from the following raw materials in parts by weight: 8-12 parts of ligusticum wallichii, 8-12 parts of pseudo-ginseng, 6-8 parts of pepper, 8-12 parts of fructus cnidii, 3-6 parts of wormwood, 8-12 parts of aloe, 2-4 parts of trehalose, 2-4 parts of mint, 0.1-0.2 part of alkyl glycoside, 0.03-0.05 part of osmotic pressure regulator and 0.01-0.02 part of plant organic acid.
3. The liniment for treating psoriasis according to claim 1 or 2, wherein the tonicity modifier is calcium chloride.
4. The liniment for treating psoriasis according to claim 1 or 2, wherein the plant organic acid is selected from tartaric acid, citric acid, and mixtures thereof in a ratio of 2-3: 1, in terms of mass ratio.
5. The process for the preparation of the liniment for the treatment of psoriasis according to claim 1 or 2, comprising the following steps:
(1) pulverizing rhizoma Ligustici Chuanxiong, Notoginseng radix, fructus Zanthoxyli, fructus Cnidii, folium Artemisiae Argyi, and herba Menthae, mixing, adjusting water content to 40-50%, and treating with steam for 30-35 min; cooling to obtain Chinese medicinal powder;
(2) adding the traditional Chinese medicine powder into glutinous rice wine 6-8 times of the weight of the traditional Chinese medicine powder to mix into a mixture, adding 0.06-0.07% of compound bacterial liquid into the mixture, fermenting for 3-4 days at 25-30 ℃, and filtering to obtain glutinous rice wine extracting solution and filter residue;
(3) adding water 10-12 times the weight of the residue into the residue, decocting for 1-1.5 hr, adding acid, stirring, cooling to 40-45 deg.C, maintaining the temperature, stirring, extracting for 25-30min, filtering, and cooling to obtain water extract;
(4) squeezing Aloe to obtain Aloe juice; mixing the glutinous rice wine extractive solution, water extractive solution, Aloe juice, trehalose, alkyl glycoside, and osmotic pressure regulator, homogenizing, and making into liniment.
6. The method for preparing the liniment for treating psoriasis according to claim 5, wherein the alcohol degree of the glutinous rice wine is 10 to 15 °.
7. The method for preparing the liniment according to claim 5, wherein the compound bacterial liquid is a compound bacterial liquid obtained from aspergillus and yeast.
8. The method for preparing the liniment according to claim 5, wherein the viable count of the aspergillus is 3-5 x 108cfu/ml, viable count of yeast is 1-2 × 106cfu/ml。
CN201911276351.4A 2019-12-12 2019-12-12 Ointment for treating psoriasis and preparation method thereof Withdrawn CN112972578A (en)

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Application Number Priority Date Filing Date Title
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