CN111700989B - Traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis and preparation method thereof - Google Patents

Traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis and preparation method thereof Download PDF

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CN111700989B
CN111700989B CN202010715000.5A CN202010715000A CN111700989B CN 111700989 B CN111700989 B CN 111700989B CN 202010715000 A CN202010715000 A CN 202010715000A CN 111700989 B CN111700989 B CN 111700989B
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tinea pedis
dispelling wind
treating tinea
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CN111700989A (en
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陈琳莉
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Hunan Nongda Health Industry Development Co ltd
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Abstract

The invention relates to a traditional Chinese medicine composition for dispelling wind and eliminating dampness and treating tinea pedis and a preparation method thereof, and the traditional Chinese medicine composition comprises the following raw material components: impatiens balsamina, lycopodium clavatum, swordlike atractylodes rhizome, oriental blueberry leaf, cortex acanthopanacis, pericarpium arecae, sargentgloryvine stem, rhizoma acori graminei, pepper and semen cuscutae. The invention has the beneficial effects that: the traditional Chinese medicine composition for dispelling wind and removing dampness and treating tinea pedis disclosed by the invention is prepared from a plurality of specific raw materials of garden balsam stem, lycopodium clavatum, tuber of swordlike clubmoss, oriental blueberry leaf, cortex acanthopanacis, pericarpium arecae, sargentgloryvine stem, rhizoma acori graminei, pepper and semen cuscutae, so that the various raw materials are mutually matched and act together, and a relatively outstanding effect of treating tinea pedis can be achieved. The effective rate of the invention for treating tinea pedis reaches 95%, the treatment range is wide, the effect is fast, and the tinea pedis is not easy to recur after healing. In addition, the composition also has the effects of assisting in regulating sleep, maintaining beauty and keeping young, and enhancing immunity, thereby playing a role in health preservation and health care.

Description

Traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis and preparation method thereof
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for dispelling wind, removing dampness and treating tinea pedis and a preparation method thereof.
Background
Tinea pedis, commonly known as dermatophytosis, is caused by fungal infection, and skin damage of the dermatophytosis usually occurs on one side (namely one foot) first and is infected on the opposite side after weeks or months. Blisters appear primarily on the ventral and lateral aspect of the toes, most commonly between the three and four toes, and also appear on the plantar aspect as small blisters which are deep in nature and gradually merge into large blisters. Skin lesions of tinea pedis are characterized by a clear border that gradually spreads outward. Erosion, fluid seepage, bacterial infection, pustule, etc. may occur due to disease development or scratching.
Regarding the treatment of tinea pedis, western medicines mainly comprise antifungal medicines, are easy to generate medicine dependence, are difficult to treat thoroughly, are easy to relapse, and cause great pain to tinea pedis patients, and the existing traditional Chinese medicine treatment scheme has the problems of unobvious effect and slow effect, so that the improvement is urgently needed.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for dispelling wind and eliminating dampness and treating tinea pedis, and the traditional Chinese medicine composition has a remarkable effect of treating tinea pedis, is not easy to relapse after healing and is low in treatment cost.
The second purpose of the invention is to provide a preparation method of the traditional Chinese medicine composition for dispelling wind and eliminating dampness and treating tinea pedis.
In order to achieve the purpose, the invention adopts the following technical scheme:
a traditional Chinese medicine composition for dispelling wind and eliminating dampness and treating tinea pedis comprises the following raw material components: impatiens balsamina, lycopodium clavatum, swordlike atractylodes rhizome, oriental blueberry leaf, cortex acanthopanacis, pericarpium arecae, sargentgloryvine stem, rhizoma acori graminei, pepper and semen cuscutae.
The prescription mechanism of the invention is that garden balsam stem, swordlike atractylodes rhizome and slenderstyle acanthopanax bark have the effects of eliminating dampness and dispelling cold, promoting blood circulation and removing blood stasis, clearing heat and removing toxicity, grassleaf sweelflag rhizome has the effect of eliminating dampness and turbidity, south dodder seed has the effect of tonifying kidney qi, lycopodium clavatum, Chinese mugwort leaf and sargentgloryvine stem have the effects of enhancing the effects of promoting blood circulation and removing blood stasis, killing parasites and relieving itching, and areca peel and pepper have the effects of promoting diuresis and relieving swelling, killing parasites and relieving itching. The composition disclosed by the invention is a formula matched with each other, can achieve better effects of clearing damp and dispelling cold, inducing diuresis for removing edema, killing parasites and relieving itching, and has a remarkable treatment effect on tinea pedis. The invention has especially obvious effects on pain and fever of related joints, stiffness of bone joints, limitation of bone joint movement, foot odor and foot itching. The composition of the invention is mainly used for treating tinea pedis due to cold-dampness invasion, kidney qi exhaustion, turbid toxin congestion, blood stasis retardation, dampness and turbidity removal, qi and blood regulation, and parasite killing and itching relieving, so that the tinea pedis is treated both from the root and the symptoms and is not easy to relapse after healing.
The composition is an ancient prescription of Dong nationality extending under Dong medical culture, has simple prescription, but remarkable medicinal effect, and preliminary clinical tests show that the total effective rate of treating tinea pedis of the invention reaches 95 percent, is obviously superior to other traditional Chinese medicines of the same type, and compared with the treatment method adopting the existing anti-inflammatory antibacterial western medicines and hormone medicines, the treatment process of the invention does not generate medicine dependence, has stable treatment effect and low cost, and has the characteristics of simple preparation method and convenient use.
As a preferred embodiment, the traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis comprises the following raw materials in parts by weight: 5-9 parts of garden balsam stem, 5-9 parts of lycopodium clavatum, 5-7 parts of swordlike atractylodes rhizome, 5-7 parts of oriental blueberry leaf, 5-7 parts of cortex acanthopanacis, 5-7 parts of pericarpium arecae, 5-7 parts of sargentgloryvine stem, 3-5 parts of rhizoma acori graminei, 3-5 parts of pepper and 3-5 parts of semen cuscutae. More preferably, the raw material components include: 7 parts of garden balsam stem, 7 parts of lycopodium clavatum, 6 parts of swordlike atractylodes rhizome, 6 parts of oriental blueberry leaf, 6 parts of cortex acanthopanacis, 6 parts of pericarpium arecae, 6 parts of sargentgloryvine stem, 4 parts of rhizoma acori graminei, 4 parts of pepper and 4 parts of semen cuscutae.
As a preferred embodiment, the traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis of the invention further comprises the following raw material components: 1-3 parts of salvia miltiorrhiza, 0.5-1.5 parts of macleaya cordata and 1-3 parts of uncaria. Dan Shen has the action of dredging meridians and can help to promote blood circulation. The macleaya cordata can enhance the effects of dispelling wind, removing toxicity, promoting qi circulation, relieving swelling and killing parasites. Ramulus Uncariae cum uncis has effects of calming endogenous wind, suppressing hyperactive liver, and clearing heat.
As a preferred embodiment, the traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis of the invention further comprises the following raw material components: 1-3 parts of wormwood. The folium Artemisiae Argyi can enhance the effects of eliminating dampness, relieving itching and dispelling cold.
The invention also provides a preparation method of the traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis, which comprises the following steps: (1) taking the raw materials, respectively removing impurities and drying for later use, wherein the drying is natural drying or baking, and preferably, the drying is carried out until the water content is below 10%; (2) weighing the raw materials according to the parts by weight, respectively crushing, preferably crushing to the particle size of 20-60 meshes to obtain raw material coarse powder, and fully mixing the raw material coarse powder to obtain the traditional Chinese medicine composition for dispelling wind and eliminating dampness and treating tinea pedis. For convenient use, it can be packaged into non-woven cloth bags in an amount of 20-30 g/bag. When in use, 1-2 small bags are taken, poured into boiling water for soaking for about 4-5 minutes, then cold water is added to adjust the water temperature to the proper water temperature, and then the feet are bathed for about 15-30 minutes until the forehead slightly sweats, and the bath lotion is taken once a day.
The traditional Chinese medicine composition for dispelling wind and eliminating dampness and treating tinea pedis can be added with auxiliary components and prepared into various medicinal dosage forms suitable for medical use according to the conventional technology in the field, wherein the medicinal dosage forms include but are not limited to cream, liquid liniment, spray and the like.
The invention has the beneficial effects that:
the traditional Chinese medicine composition for dispelling wind and removing dampness and treating tinea pedis disclosed by the invention is prepared from a plurality of specific raw materials of garden balsam stem, lycopodium clavatum, tuber of swordlike clubmoss, oriental blueberry leaf, cortex acanthopanacis, pericarpium arecae, sargentgloryvine stem, rhizoma acori graminei, pepper and semen cuscutae, so that the various raw materials are mutually matched and act together, and a relatively outstanding effect of treating tinea pedis can be achieved. The effective rate of the invention for treating tinea pedis reaches 95%, the treatment range is wide, the effect is fast, and the tinea pedis is not easy to recur after healing. In addition, the composition also has the effects of assisting in regulating sleep, maintaining beauty and keeping young, and enhancing immunity, thereby playing a role in health preservation and health care. The composition of the invention is easy to prepare, has low treatment cost and is suitable for popularization and utilization.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention. In the following examples 1 part represents 1 g.
Example 1
The embodiment provides a traditional Chinese medicine composition for dispelling wind and removing dampness and treating tinea pedis, which is prepared from the following raw materials in parts by weight: 5 parts of garden balsam stem, 9 parts of lycopodium clavatum, 5 parts of swordlike atractylodes rhizome, 7 parts of oriental blueberry leaf, 5 parts of cortex acanthopanacis, 7 parts of pericarpium arecae, 5 parts of sargentgloryvine stem, 5 parts of rhizoma acori graminei, 3 parts of pepper and 5 parts of semen cuscutae.
The preparation method of the traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis in the embodiment comprises the following steps:
(1) taking the raw materials, respectively removing impurities, and naturally drying in the sun until the water content is below 10% for later use;
(2) weighing the raw materials according to the parts by weight, respectively crushing to obtain raw material coarse powder with the particle size of 20 meshes, fully mixing the raw material coarse powder, subpackaging into a non-woven fabric bag, and packaging into 20 g/bag to obtain the traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis.
Example 2
The embodiment provides a traditional Chinese medicine composition for dispelling wind and removing dampness and treating tinea pedis, which is prepared from the following raw materials in parts by weight: 9 parts of garden balsam stem, 5 parts of lycopodium clavatum, 7 parts of swordlike atractylodes rhizome, 5 parts of oriental blueberry leaf, 7 parts of cortex acanthopanacis, 5 parts of pericarpium arecae, 7 parts of sargentgloryvine stem, 3 parts of rhizoma acori graminei, 5 parts of pepper, 3 parts of semen cuscutae, 3 parts of salvia miltiorrhiza, 0.5 part of macleaya cordata, 3 parts of uncaria and 1 part of wormwood.
The preparation method of the traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis in the embodiment comprises the following steps:
(1) taking the raw materials, respectively removing impurities, and naturally drying in the sun until the water content is below 10% for later use;
(2) weighing the raw materials according to the parts by weight, respectively crushing to obtain raw material coarse powder with the particle size of 60 meshes, fully mixing the raw material coarse powder, subpackaging into a non-woven fabric bag, and packaging into 30 g/bag to obtain the traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis.
Example 3
The embodiment provides a traditional Chinese medicine composition for dispelling wind and removing dampness and treating tinea pedis, which is prepared from the following raw materials in parts by weight: 7 parts of garden balsam stem, 7 parts of lycopodium clavatum, 6 parts of swordlike atractylodes rhizome, 6 parts of oriental blueberry leaf, 6 parts of cortex acanthopanacis, 6 parts of pericarpium arecae, 6 parts of sargentgloryvine stem, 4 parts of rhizoma acori graminei, 4 parts of pepper, 4 parts of semen cuscutae, 1 part of salvia miltiorrhiza, 1.5 parts of macleaya cordata, 1 part of uncaria and 3 parts of wormwood.
The preparation method of the traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis in the embodiment comprises the following steps:
(1) taking the raw materials, respectively removing impurities, and drying at 50 ℃ until the water content is below 10% for later use;
(2) weighing the raw materials according to the parts by weight, respectively crushing to obtain raw material coarse powder with the particle size of 40 meshes, fully mixing the raw material coarse powder, subpackaging into a non-woven fabric bag, and packaging into 20 g/bag to obtain the traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis.
Comparative example 1
The comparative example provides a traditional Chinese medicine composition for dispelling wind and removing dampness and treating tinea pedis, which comprises the following raw materials in parts by weight: 13 parts of garden balsam stem, 7 parts of lycopodium clavatum, 6 parts of swordlike atractylodes rhizome, 6 parts of cortex acanthopanacis, 6 parts of areca peel, 6 parts of sargentgloryvine stem, 4 parts of rhizoma acori graminei, 4 parts of pepper, 4 parts of semen cuscutae, 1 part of salvia miltiorrhiza, 1.5 parts of macleaya cordata, 1 part of uncaria and 3 parts of wormwood. The preparation method is the same as example 3.
Comparative example 2
The comparative example provides a traditional Chinese medicine composition for dispelling wind and removing dampness and treating tinea pedis, which comprises the following raw materials in parts by weight: 7 parts of garden balsam stem, 7 parts of lycopodium clavatum, 6 parts of swordlike atractylodes rhizome, 6 parts of oriental blueberry leaf, 6 parts of cortex acanthopanacis, 6 parts of pericarpium arecae, 6 parts of beautiful sweetgum fruit, 4 parts of rhizoma acori graminei, 4 parts of pepper, 4 parts of semen cuscutae, 1 part of salvia miltiorrhiza, 1.5 parts of macleaya cordata, 1 part of uncaria and 3 parts of wormwood. The preparation method is the same as example 3.
Experimental study on the treatment of tinea pedis
1. The general data selects 80 cases of tinea pedis patients, the average age is 36.15 +/-8.55 years, the average course of disease is 3.52 +/-1.26 years, and the diagnosis standard refers to the expert consensus of the dermatology division mycology group of Chinese tinea pedis diagnosis and treatment-China physician Association, wherein 38 cases are toe spaces, 26 cases are foot side edges or soles and 16 cases are combined according to skin lesion parts; according to the skin lesion types, 42 cases are erosive skin lesions, 18 cases are blister skin lesions, and 20 cases are scaly keratotic skin lesions. All patients were randomly divided into 4 groups of test group, control group 1, control group 2 and control group 3, each group had 20 cases, and each group had no significant difference in age distribution, disease course, skin lesion site and skin lesion type, and was comparable.
2. Test methods the test group used the Chinese medicinal composition of the present invention in example 3, the control group 1 used the Chinese medicinal composition of comparative example 1, the control group 2 used the Chinese medicinal composition of comparative example 2, and the control group 3 used a commercial foot bath bag. The using method comprises the following steps: soaking 1 bag (20g) in 1L of boiling water for 5 min, adding 3L of warm water to adjust the water temperature to a proper temperature, bathing foot for 20 min once a day, and taking 15 days as a treatment course for two continuous treatment courses.
3. The treatment effect judgment standard is used for curing: the skin lesion symptoms are completely disappeared, and the fungus microscopic examination is negative; the effect is shown: the skin lesion symptom disappears by more than 90 percent, pruritus, suppuration and herpes are obviously relieved, and superficial fungus microscopy is negative; the method has the following advantages: skin lesion symptom disappears by 50% -90%, pruritus, suppuration and herpes are obviously relieved, and superficial mycoscope examination is negative; and (4) invalidation: the skin lesion symptom disappears by less than 50 percent, and pruritus, suppuration and herpes are not relieved. The total effective rate is (recovery + effect)/the number of cases is multiplied by 100 percent
4. The test results are shown in Table 1.
TABLE 1
Group of Number of examples Recovery method Show effect Is effective Invalidation The total effective rate%
Test group 20 5(25) 8(40) 6(30) 1(5) 95.00
Control group 1 20 3(15) 4(20) 10(50) 3(15) 85.00
Control group 2 20 3(15) 6(30) 8(40) 3(15) 85.00
Control group 3 20 2(10) 2(10) 12(60) 4(20) 80.00
The results show that the total effective rate of the test group is 95%, the effective rates of the control group 1, the control group 2 and the control group 3 are respectively 85%, 85% and 80%, and the test group is obviously superior to other groups. The test group is the traditional Chinese medicine composition of the embodiment 3 of the invention, the control group 1 removes vaccinium bracteatum leaves on the basis of the embodiment 3 but the total amount of the raw materials is unchanged, and the control group 2 replaces the sargentgloryvine stems on the basis of the embodiment 3 with the fructus liquidambaris, so that the treatment effect is obviously reduced when part of the raw materials in the composition are changed, and the composition obtains a better treatment effect by combining the specific raw materials to be matched with each other by combining the effects of the commercial foot bath bags represented by the control group 3, and has obvious superiority compared with the prior art.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.

Claims (5)

1. A traditional Chinese medicine composition for dispelling wind and eliminating dampness and treating tinea pedis is characterized by comprising the following raw material components in parts by weight:
5-9 parts of garden balsam stem, 5-9 parts of lycopodium clavatum, 5-7 parts of swordlike atractylodes rhizome, 5-7 parts of oriental blueberry leaf, 5-7 parts of cortex acanthopanacis, 5-7 parts of pericarpium arecae, 5-7 parts of sargentgloryvine stem, 3-5 parts of rhizoma acori graminei, 3-5 parts of pepper, 3-5 parts of semen cuscutae, 1-3 parts of salvia miltiorrhiza, 0.5-1.5 parts of macleaya cordata, 1-3 parts of uncaria and 1-3 parts of wormwood.
2. The preparation method of the traditional Chinese medicine composition for dispelling wind and eliminating dampness and treating tinea pedis of the claim 1 is characterized by comprising the following steps:
(1) taking the raw materials, and respectively removing impurities and drying for later use;
(2) weighing the raw materials according to the parts by weight, respectively crushing to obtain raw material coarse powder, and fully mixing the raw material coarse powder to obtain the traditional Chinese medicine composition for dispelling wind and eliminating dampness and treating tinea pedis.
3. The method for preparing a Chinese medicinal composition for dispelling wind, removing dampness and treating tinea pedis according to claim 2, wherein the drying in step (1) is natural drying in the sun or oven drying.
4. The method for preparing a Chinese medicinal composition for dispelling wind, removing dampness and treating tinea pedis according to claim 2, wherein in the step (1), the drying is performed until the water content is less than 10%.
5. The method for preparing a Chinese medicinal composition for dispelling wind, removing dampness and treating tinea pedis according to claim 2, wherein the pulverizing to a particle size of 20-60 mesh is performed in step (2).
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