CN107233420A - It is a kind of with foot-bath traditional Chinese medicine composition stimulated the circulation of the blood and cause the muscles and joints to relax and its preparation method and application - Google Patents
It is a kind of with foot-bath traditional Chinese medicine composition stimulated the circulation of the blood and cause the muscles and joints to relax and its preparation method and application Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/716—Clematis (leather flower)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Abstract
The invention discloses a kind of with the foot-bath traditional Chinese medicine composition stimulated the circulation of the blood and cause the muscles and joints to relax, it is made up of the bulk drug of following parts by weight：10 15 parts of lopseed, 10 19 parts of cassia twig, 10 15 parts of ramulus mori, 10 15 parts of lycopodium calvatum, 10 17 parts of the root of Chinese clematis, 10 19 parts of Radix Angelicae Sinensis tail, 8 15 parts of the red sage root, 8 15 parts of semen brassicae, play both sides of the street 10 17 parts, 8 12 parts of folium artemisiae argyi, 5 10 parts of Chinese prickly ash, 35 parts of asarum.The foot-bath traditional Chinese medicine composition of the present invention is for wind cold wetness type degenerative knee determined curative effect, and total effective rate is compared with significant difference (P up to 87.5% with control group<0.05)；And the improvement using group in the pain of patient, tenderness, swelling and range of motion is substantially better than control group.In addition, the foot-bath traditional Chinese medicine composition of the present invention has unique curative effect for neck-shoulder pain, lumbago and leg pain.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and its preparation method and application, more particularly to a kind of foot-bath traditional Chinese medicine composition
And its preparation method and application.
Background technology
Footbath with traditional Chinese medicines is that, with traditional Chinese medicine diagnosis and treatment principle, viscera-state doctrine, theory of channels and collaterals, holographic theory, modern foot are anti-
It is guidance to penetrate domain tyeory, and the herbal medicine of dialectical selection is ground to form into scattered be cooked into after decoction adds in warm water, biped is soaked, by good
Sexual stimulus biped echo area, dredges foot channels and collaterals, and the active ingredient of medicine is absorbed by skin surface mucous membrane acupuncture point echo area, drawn
The overall pharmacodynamics effect of body or the pharmacodynamics effect of local lesion are played, so that the QI-blood circulation at Body organs position leads to
Freely, function phase should strengthen, and reach regulation body equilibrium between yin and yang, dredge the channels, and improve metabolism in blood circulation, acceleration bodies,
And then play a part of preventing and curing diseases.
Footbath with traditional Chinese medicines has history of long standing and well established, is widely used in disease as one of traditional external therapy in motherland's medical science
The treatment of disease or auxiliary treatment.Just it is related to treat the record of disease using herbs feet bathing therapy early in the Zhou Dynasty.In period in Spring and Autumn and Warring States
Footbath with traditional Chinese medicines as a kind of daily life health care mode, and is treated disease by phase, people；In the period Tang Dynasty, people are by footbath with traditional Chinese medicines
A kind of auxiliary reset mode to disease is used as, and has medically obtained preliminary utilization；Period of Ming and Qing, with the modern times
The developmental research of medical science is promoted, and more medicines start to apply in footbath with traditional Chinese medicines, and footbath with traditional Chinese medicines therapy has been obtained further
Promote.Footbath with traditional Chinese medicines is widely used in treating the numerous areas such as inside and outside, woman, youngster, traumatology.However, lavipeditum bag of the prior art
Used mostly as fatigue-relieving, the effect of footbath with traditional Chinese medicines is weakened significantly, for the patient of wind-cold-dampness arthralgia, it is impossible to fundamentally
Solve the problems, such as.
The content of the invention
The present invention is used as fatigue-relieving mostly to solve lavipeditum bag in the prior art, and footbath with traditional Chinese medicines is weakened significantly
Effect, for the patient of wind-cold-dampness arthralgia can not tackle the problem at its root and propose it is a kind of with the lavipeditum Chinese medicine stimulated the circulation of the blood and cause the muscles and joints to relax
Composition.
To achieve the above object, the present invention uses following technical scheme：
It is a kind of with the foot-bath traditional Chinese medicine composition stimulated the circulation of the blood and cause the muscles and joints to relax, each component and its consumption part in the foot-bath traditional Chinese medicine composition
Counting scope is：10-15 parts of lopseed, 10-19 parts of cassia twig, 10-15 parts of ramulus mori, 10-15 parts of lycopodium calvatum, 10-17 parts of the root of Chinese clematis, when
Return 10-19 parts of tail, 8-15 parts of the red sage root, 8-15 parts of semen brassicae, play both sides of the street 10-17 parts, 8-12 parts of folium artemisiae argyi, 5-10 parts of Chinese prickly ash, asarum
3-5 parts；
In order to further optimize above-mentioned technical proposal, the technical measures that the present invention is taken are：
It is preferred that, each component and its consumption number scope are in the foot-bath traditional Chinese medicine composition：10-15 parts of lopseed, osmanthus
Branch 10-15 part, 10-15 parts of ramulus mori, 10-15 parts of lycopodium calvatum, 10-15 parts of the root of Chinese clematis, 10-15 parts of Radix Angelicae Sinensis tail, 8-12 parts of the red sage root, in vain
8-12 parts of mustard seed, play both sides of the street 10-15 parts, 8-12 parts of folium artemisiae argyi, 5-8 parts of Chinese prickly ash, 3-5 parts of asarum；
It is preferred that, each component and its consumption number scope are in the foot-bath traditional Chinese medicine composition：11-13 parts of lopseed, osmanthus
Branch 17-19 parts, 10-15 parts of ramulus mori, 11-13 parts of lycopodium calvatum, 15-17 parts of the root of Chinese clematis, 17-19 parts of Radix Angelicae Sinensis tail, 10-15 parts of the red sage root,
10-15 parts of semen brassicae, play both sides of the street 13-17 parts, 8-12 parts of folium artemisiae argyi, 8-10 parts of Chinese prickly ash, 3-5 parts of asarum；
It is furthermore preferred that each component and its consumption number scope are in the foot-bath traditional Chinese medicine composition：15 parts of lopseed, cassia twig
15 parts, 15 parts of ramulus mori, 15 parts of lycopodium calvatum, 15 parts of the root of Chinese clematis, 10 parts of Radix Angelicae Sinensis tail, 10 parts of the red sage root, 10 parts of semen brassicae, play both sides of the street 15
Part, 10 parts of folium artemisiae argyi, 5 parts of Chinese prickly ash, 3 parts of asarum.
The second aspect of the invention is to provide a kind of preparation method of foot-bath traditional Chinese medicine composition, and the preparation method is：
Raw material is weighed by each component and parts by weight of above-described any foot-bath traditional Chinese medicine composition, impurity elimination is cleaned, dries, be ground into
Particle, crosses 8-20 mesh sieves, encapsulation.
The third aspect of the invention is to provide a kind of application of foot-bath traditional Chinese medicine composition in arthritis；
It is preferred that, arthritis of the present invention is degenerative knee.
The present invention uses above-mentioned technical proposal, compared with prior art, have the following technical effect that：
The foot-bath traditional Chinese medicine composition of the present invention, according to Chinese medicine monarch combination principle, by these medicine organic combinations, respectively
The Zhan chief, makes each efficacy of drugs produce synergy, so as to reach the effect stimulated the circulation of the blood and cause the muscles and joints to relax.We with Wen Tongwei then, in side with
The lopseed of pungent-warm, cassia twig, lycopodium calvatum, plays both sides of the street as monarch, and lopseed and the promoting blood circulation qi-regulating power that plays both sides of the street are strong, can dredge with one
Under, the passages through which vital energy circulates of trusted subordinate's waist and knee, lycopodium calvatum dredges the network gas of limbs minor details, and the sensible limb end yang-energy of energy, and cassia twig is focused on and helped
Sun is promoted blood circulation, four medicines and for monarch drug in a prescription, can dredge all muscles along the regular meridians channels of whole body.Minister is with ramulus mori and root of Chinese clematis wind-damp dispelling, and sharp arthralgia relief is red
Ginseng and Radix Angelicae Sinensis tail strengthen the power of promoting blood circulation, dredging meridian and relieving pain.Assistant dispels exogenous wind with semen brassicae and asarum, and dredging collateral, Li Shui reaches that searching wind picks
Heresy, dehumidification swelling effect.Folium artemisiae argyi and Chinese prickly ash, fragrance are walked to alter, and help the sensible four limbs hole key of all medicines, strengthen dredging the whole body passages through which vital energy circulates qi and blood,
Promoting blood circulation and removing obstruction in channels so as to reach, clearing damp is acted on except stupid numbness.All formulas are matched, and power promoting blood circulation and removing obstruction in channels is strong, the through body muscles along the regular meridians channels of the efficacy of a drug,
The all keys of four limbs, and the medicine in the sharp joint of dehumidifying is cooperateed with, wind-damp dispelling is played altogether, except the effect of stupid numbness.
The foot-bath traditional Chinese medicine composition of the present invention is for wind cold wetness type chronic lumbocrural pain determined curative effect, and total effective rate reaches
87.5%, compared with common lavipeditum with significant difference (P<0.05)；And the foot-bath traditional Chinese medicine composition of the present invention is in patient
Pain, tenderness, the improvement of range of motion be substantially better than common lavipeditum.
The foot-bath traditional Chinese medicine composition safety of the present invention, decoction directly absorb, green remedy, simple to operate, Energy and comfort, nothing
Toxic side effect, clinic is promoted the use of.
Embodiment
The invention provides a kind of with the foot-bath traditional Chinese medicine composition stimulated the circulation of the blood and cause the muscles and joints to relax and its application.
The present invention is described in more detail below by specific embodiment, for a better understanding of the present invention,
But following embodiments are not intended to limit the scope of the invention.
Embodiment 1
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：15 parts of lopseed, 15 parts of cassia twig, ramulus mori
15 parts, 15 parts of lycopodium calvatum, 15 parts of the root of Chinese clematis, 10 parts of Radix Angelicae Sinensis tail, 10 parts of the red sage root, 10 parts of semen brassicae, play both sides of the street 15 parts, folium artemisiae argyi 10
Part, 5 parts of Chinese prickly ash, 3 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 8 mesh sieves, encapsulation are crossed.
Embodiment 2
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：12 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi, flower
8 parts of green pepper, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 10 mesh sieves, encapsulation are crossed.
Embodiment 3
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：12 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi, flower
8 parts of green pepper, 3 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 12 mesh sieves, encapsulation are crossed.
Embodiment 4
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：12 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 8 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 10 parts of folium artemisiae argyi, flower
8 parts of green pepper, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 14 mesh sieves, encapsulation are crossed.
Embodiment 5
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：12 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 8 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 15 parts, 8 parts of folium artemisiae argyi, flower
8 parts of green pepper, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 14 mesh sieves, encapsulation are crossed.
Embodiment 6
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：12 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 10 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi,
8 parts of Chinese prickly ash, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 16 mesh sieves, encapsulation are crossed.
Embodiment 7
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：12 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 10 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi,
8 parts of Chinese prickly ash, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 8 mesh sieves, encapsulation are crossed.
Embodiment 8
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：12 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 15 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi, flower
8 parts of green pepper, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 10 mesh sieves, encapsulation are crossed.
Embodiment 9
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：12 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 15 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi, flower
8 parts of green pepper, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 14 mesh sieves, encapsulation are crossed.
Embodiment 10
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：12 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 15 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi, flower
8 parts of green pepper, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 12 mesh sieves, encapsulation are crossed.
Embodiment 11
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：12 parts of lopseed, 12 parts of cassia twig, ramulus mori
15 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi, flower
8 parts of green pepper, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 16 mesh sieves, encapsulation are crossed.
Embodiment 12
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：12 parts of lopseed, 15 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi, flower
8 parts of green pepper, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 12 mesh sieves, encapsulation are crossed.
Embodiment 13
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：15 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi, flower
8 parts of green pepper, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 14 mesh sieves, encapsulation are crossed.
Embodiment 14
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：15 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi, flower
8 parts of green pepper, 3 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 18 mesh sieves, encapsulation are crossed.
Embodiment 15
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：15 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi, flower
10 parts of green pepper, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 10 mesh sieves, encapsulation are crossed.
Embodiment 16
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：15 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 12 parts of folium artemisiae argyi,
10 parts of Chinese prickly ash, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 20 mesh sieves, encapsulation are crossed.
Embodiment 17
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：15 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 15 parts, 8 parts of folium artemisiae argyi, flower
8 parts of green pepper, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 8 mesh sieves, encapsulation are crossed.
Embodiment 18
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：15 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 15 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi,
8 parts of Chinese prickly ash, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 12 mesh sieves, encapsulation are crossed.
Embodiment 19
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：15 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 15 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi,
8 parts of Chinese prickly ash, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 14 mesh sieves, encapsulation are crossed.
Embodiment 20
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：15 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 15 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi, flower
8 parts of green pepper, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 20 mesh sieves, encapsulation are crossed.
Embodiment 21
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：15 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 12 parts of lycopodium calvatum, 15 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi, flower
8 parts of green pepper, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 10 mesh sieves, encapsulation are crossed.
Embodiment 22
The component and its consumption number of the foot-bath traditional Chinese medicine composition of the present embodiment be：15 parts of lopseed, 12 parts of cassia twig, ramulus mori
12 parts, 15 parts of lycopodium calvatum, 12 parts of the root of Chinese clematis, 12 parts of Radix Angelicae Sinensis tail, 8 parts of the red sage root, 8 parts of semen brassicae, play both sides of the street 12 parts, 8 parts of folium artemisiae argyi, flower
8 parts of green pepper, 5 parts of asarum.
Preparation method：Above-mentioned foot-bath traditional Chinese medicine composition is weighed into raw material by above-mentioned parts by weight, impurity elimination is cleaned, dries, is crushed
Into particle, 10 mesh sieves, encapsulation are crossed.
Following experiments be on the basis of multiple creative experiment, for technical scheme carried out it is conclusive
Experiment.
Drug effect application test experience of the medicine of the present invention in for degenerative knee
1 experiment patient data
The patient that this research case is gone to a doctor from January, 2015 in December, 2016 in institute of traditional Chinese medicine of Shenzhen.Pacify random number
Word table method is randomly divided into using group one, using two and control group is organized, totally 120 people, wherein every group of 40 people, male 56, and women 64
Example, the oldest 71 years old, minimum 45 years old, average age 52 ± 6.62 years old, the course of disease was most short 3 months, most long 10 years, average course of disease 3
± 3.11 years.Three groups of patients are in sex, age, the equal no significant difference of the course of disease, with comparativity.
2 diagnostic criteria
Western medicine diagnostic criteria：The gonitis diagnostic criteria formulated with reference to U.S.'s rheumatism (ACR)：1. age >=45 year old；
2. knee joint flexion-extension motion has the friction sound；3. knee joint peripheral pain, local tenderness is obvious；4. joint morning stiffness ＞ 30min, knee
Periarticular soft tissues swelling；5. x-ray shows that knee joint epiphysis edge has spur to be formed.According to clinical symptoms, sign combination shadow
Diagnosis can be made as learning performance.
Tcm diagnosis standard：With reference to State Administration of Traditional Chinese Medicine's issue in 1994《Chinese medical disease Standardization of diagnosis and curative effect》Intend
It is fixed：Primary symptom：Arthralgia swelling, pain exaggerated by catching cold, pain alleviated while getting warmth, joint joint stuffiness, morning stiffness, joint is abnormal；Secondary disease：Mouth is light not
Yearningly, aversion to wind and cold, overcast and rainy exacerbation, limbs are heavy, and tongue nature is light, tongue is white, deep tense pulse.
Inclusive criteria：1. degenerative knee Western medicine diagnostic criteria person is met；2. without operative treatment, conservative make is agreed to
User；3. informed consent, voluntarily signs letter of consent and receives this programme user.
Exclusion standard：1. possess obvious surgical indication, guard using without obvious curative effects person；2. local skin is damaged, infect
Person；3. non-degenerative knee patient；4. serious viscera disease, insufficiency or the multiple tumor disease of whole body are associated with or tight
Holergasia patient.
3 application methods：
Use group one：Using the parts by weight medicine described in example 1, rear small fire is boiled in 2500ml water and is decocted 30 minutes,
Start foot bath when decoction is cooled to 30-50 DEG C, the water surface soaks 20 minutes, 1 time a day, continuous foot bath 1 to not having ankle
Month.There are heating, topical skin infections, systolic pressure to reach more than 180mmHg, serious acute bleeding patients during use, seriously
Cardiac, forbids to use.
Use group two：Using the parts by weight medicine described in example 22, rear small fire is boiled in 2500ml water and is decocted 30 minutes,
Start foot bath when decoction is cooled to 30-50 DEG C, the water surface soaks 20 minutes, 1 time a day, continuous foot bath 1 to not having ankle
Month.There are heating, topical skin infections, systolic pressure to reach more than 180mmHg, serious acute bleeding patients during use, seriously
Cardiac, forbids to use.
Control group：Western medicine is used, oral Piroxicam tablets 20mg, and one time a day, 30 days courses for the treatment of.
4 observation index
4.1 Lequesne index scores：Patient is made with reference to " LequesneShi knee joints orphan's star arthritis functional scale "
Become with whether there is joint rest pain, joint mobilization pain, tenderness, swelling, morning stiffness and locomotor activity during preceding flesh treatment end
Change 6 aspect carry out statistical analyses, 0~3 point of integrating system is respectively adopted according to different degrees of rank, using 6 integration summations as
Lequesne index final scores.Higher its function of joint of prompting of Lequesne integrations is limited more obvious, and the extent of damage is more tight
Weight.
4.2 Lysholm knee joints score：By 25 points of pain, 25 points of unstability degree, 15 points of locking sense, 10 points of swelling,
Walk lamely 5 points, stair climb 10 points, 5 points of crouching appearance, use 8 parameters of supporter 5 point to constitute, 100 points altogether.Normally：Patient's knee is closed
Section counts 100 points without any discomfort symptom.It is excellent：>=80 points；It is good：70~79 points；In：60~69 points；Difference：60 points of ＜.
4.3 pain visual analogue scales score (visual analogue scale, VAS)：Level with a long 10cm is straight
Line, two ends are respectively 0 point of end and 10 points of ends, and 0 point of expression is painless, and 10 points represent most pain, it is desirable to which patient exists respectively before and after
The position for representing its gonalgia degree is marked on straight line, operator gives after using ruler measurement distance according to its selected location
To quantify, scored.
5 efficacy assessment standards：Cure：Symptom and sign disappear, and knee joint uses rear symptom integral slip without sense of discomfort
>=95%；It is effective：Symptom and sign are alleviated substantially, and knee articulation is unrestricted, and slip >=70%, and ＜ 95 are integrated after use
In %；Effectively：Symptom and sign alleviation are more apparent, but knee articulation is slightly limited, and integrate slip >=30%, and ＜
70%；It is invalid：Knee joint symptom and sign are not improved, and slip ＜ 30% is integrated after use.
6 recurrence rates are counted：According to " LequesneShi knee joints orphan's star arthritis functional scale ", patient goes out again after
Existing rest pain, joint mobilization pain, tenderness, swelling, morning stiffness and locomotor activity decline either side can determine that as recurrence.It is right
Cure follow-up of patients to observe 6 months, count recurrence rate.
7 results
(1) three group of patient clinical comparitive study
Three groups of patients are completed to use by the course for the treatment of, without the case that comes off.Use one total effective rate 87.5% of group, obvious effective rate
70.0%；Use two total effective rates 80.0% of group, obvious effective rate 55.0%, control group total effective rate 70.0%, obvious effective rate 35.0%.
Compared using group with control group, total effective rate and obvious effective rate are above control group (P<0.05).
1 three groups of patients of table use rear Clinical efficacy comparison
Note：Compared with control group, * P<0.05.
(2) three groups of patients are compared using front and rear Lequesne index scores
Three groups use the preceding not statistically significant (P of Lequesne index scores comparing difference>0.05), with comparativity；Make
Relatively decline (equal P using preceding with rear three groups of Lequesne index scores<0.05)；Compared Lequesne with control group using group to refer to
Number scoring decline becomes apparent (P<0.05).
2 three groups of patients of table are compared using rear Lequesne index scores
Note：Compared with before this group of use, * P<0.05；Compared with after control group use, #P<0.05.
(3) three groups of patients are compared using the scoring of front and rear Lysholm knee joints
Three groups use the not statistically significant (P of preceding Lysholm knee joints scoring grading situation comparing difference>0.05), have
Comparativity；Three groups using rear acceptance rate compared with the (P that increased before use<0.05)；It is better than control group using acceptance rate using group
(P<0.05).It is shown in Table 3.
3 three groups of patients of table are compared using front and rear Lysholm knee joints scoring grading situation
Note：Compared with before this group of use, * P<0.05；Compared with after control group use, #P<0.05.
(4) three groups of patients are compared using front and rear VAS scorings
Three groups use the not statistically significant (P of preceding VAS scoring comparing differences>0.05), with comparativity；After three groups of uses
VAS scorings relatively decline (equal P using preceding<0.05)；Control group (P is substantially less than using the rear VAS scorings of group use<0.05), see
Table 4.Lavipeditum lotion is pointed out to have more advantage in terms of gonalgia degree is reduced.
4 three groups of patients of table are compared using front and rear VAS scorings
Note：Compared with before this group of use, * P<0.05；Compared with after control group use, #P<0.05.
(5) three groups of follow-up of patients's late result observations
Using rear follow-up 6 months, control group is substantially less than using a group recurrence rate, difference has significant difference (P<0.05),
It is shown in Table 5.Illustrate that the late result of lavipeditum lotion is substantially better than oral drugs.
Recurrence rate compares during 5 three groups of follow-up of patients of table
Note：Compared with control group, * P<0.05.
The lavipeditum prescription of the present invention also clearly, is suitable for wind for the bone joint pain curative effect in addition to gonitis
Cold-dampness numbness type chronic lumbocrural pain patient, recurrence probability is small, and toxic side effect less, is particularly suitable for long-term treatment chronic joint sufferer
Person.
The specific embodiment of the present invention is described in detail above, but it is intended only as example, and the present invention is not limited
It is formed on particular embodiments described above.To those skilled in the art, it is any to the equivalent modifications that carry out of the present invention and
Substitute also all among scope of the invention.Therefore, the impartial conversion made without departing from the spirit and scope of the invention and
Modification, all should be contained within the scope of the invention.
Claims (7)
1. it is a kind of with the foot-bath traditional Chinese medicine composition stimulated the circulation of the blood and cause the muscles and joints to relax, it is characterised in that：Each component in the foot-bath traditional Chinese medicine composition
And its consumption number scope is：10-15 parts of lopseed, 10-19 parts of cassia twig, 10-15 parts of ramulus mori, 10-15 parts of lycopodium calvatum, the root of Chinese clematis
10-17 parts, 10-19 parts of Radix Angelicae Sinensis tail, 8-15 parts of the red sage root, 8-15 parts of semen brassicae, play both sides of the street 10-17 parts, 8-12 parts of folium artemisiae argyi, Chinese prickly ash 5-
10 parts, 3-5 parts of asarum.
2. foot-bath traditional Chinese medicine composition according to claim 1, it is characterised in that：Each component in the foot-bath traditional Chinese medicine composition
And its consumption number scope is：10-15 parts of lopseed, 10-15 parts of cassia twig, 10-15 parts of ramulus mori, 10-15 parts of lycopodium calvatum, the root of Chinese clematis
10-15 parts, 10-15 parts of Radix Angelicae Sinensis tail, 8-12 parts of the red sage root, 8-12 parts of semen brassicae, play both sides of the street 10-15 parts, 8-12 parts of folium artemisiae argyi, Chinese prickly ash 5-
8 parts, 3-5 parts of asarum.
3. foot-bath traditional Chinese medicine composition according to claim 1, it is characterised in that：Each component in the foot-bath traditional Chinese medicine composition
And its consumption number scope is：11-13 parts of lopseed, 17-19 parts of cassia twig, 10-15 parts of ramulus mori, 11-13 parts of lycopodium calvatum, the root of Chinese clematis
15-17 parts, 17-19 parts of Radix Angelicae Sinensis tail, 10-15 parts of the red sage root, 10-15 parts of semen brassicae, play both sides of the street 13-17 parts, 8-12 parts of folium artemisiae argyi, Chinese prickly ash
8-10 parts, 3-5 parts of asarum.
4. foot-bath traditional Chinese medicine composition according to claim 1, it is characterised in that：Each component in the foot-bath traditional Chinese medicine composition
And its consumption number scope is：15 parts of lopseed, 15 parts of cassia twig, 15 parts of ramulus mori, 15 parts of lycopodium calvatum, 15 parts of the root of Chinese clematis, Radix Angelicae Sinensis tail
10 parts, 10 parts of the red sage root, 10 parts of semen brassicae, play both sides of the street 15 parts, 10 parts of folium artemisiae argyi, 5 parts of Chinese prickly ash, 3 parts of asarum.
5. according to the preparation method of any described foot-bath traditional Chinese medicine compositions of claim 1-4, it is characterised in that：The preparation side
Method is：Raw material is weighed by each component and parts by weight of any described foot-bath traditional Chinese medicine compositions of claim 1-4, cleans and goes
It is miscellaneous, dry, be ground into particle, cross 8-20 mesh sieves, encapsulation.
6. according to application of any described foot-bath traditional Chinese medicine compositions of claim 1-4 in arthritis.
7. application of the foot-bath traditional Chinese medicine composition according to claim 6 in arthritis, it is characterised in that：The arthritis
For degenerative knee.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109289023A (en) * | 2018-11-20 | 2019-02-01 | 梁业卿 | A kind of liquid medicine and preparation method thereof of dispellieg cold and dampness degrading the channel |
| CN110063994A (en) * | 2019-04-09 | 2019-07-30 | 中国中医科学院中医临床基础医学研究所 | A kind of footbath with traditional Chinese medicines prescription and preparation method thereof for treating sprain of ankle joint |
| CN111700989A (en) * | 2020-07-23 | 2020-09-25 | 湖南农达健康产业发展有限责任公司 | Traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis and preparation method thereof |
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| CN104587442A (en) * | 2015-02-12 | 2015-05-06 | 上海市闸北区中医医院 | Foot bath traditional Chinese medicine composition for treating wind-cold-dampness arthralgia and application of foot bath traditional Chinese medicine composition |
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2017
- 2017-06-29 CN CN201710517586.2A patent/CN107233420A/en active Pending
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| CN104587442A (en) * | 2015-02-12 | 2015-05-06 | 上海市闸北区中医医院 | Foot bath traditional Chinese medicine composition for treating wind-cold-dampness arthralgia and application of foot bath traditional Chinese medicine composition |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109289023A (en) * | 2018-11-20 | 2019-02-01 | 梁业卿 | A kind of liquid medicine and preparation method thereof of dispellieg cold and dampness degrading the channel |
| CN110063994A (en) * | 2019-04-09 | 2019-07-30 | 中国中医科学院中医临床基础医学研究所 | A kind of footbath with traditional Chinese medicines prescription and preparation method thereof for treating sprain of ankle joint |
| CN110063994B (en) * | 2019-04-09 | 2022-06-24 | 中国中医科学院中医临床基础医学研究所 | Traditional Chinese medicine foot bath composition for treating old ankle sprain |
| CN111700989A (en) * | 2020-07-23 | 2020-09-25 | 湖南农达健康产业发展有限责任公司 | Traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis and preparation method thereof |
| CN111700989B (en) * | 2020-07-23 | 2022-02-08 | 湖南农达健康产业发展有限责任公司 | Traditional Chinese medicine composition for dispelling wind, eliminating dampness and treating tinea pedis and preparation method thereof |
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