CN108310185A - Treat the drug and preparation method thereof of osteoproliferation and disc herniation - Google Patents

Treat the drug and preparation method thereof of osteoproliferation and disc herniation Download PDF

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CN108310185A
CN108310185A CN201810336253.4A CN201810336253A CN108310185A CN 108310185 A CN108310185 A CN 108310185A CN 201810336253 A CN201810336253 A CN 201810336253A CN 108310185 A CN108310185 A CN 108310185A
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毛天
毛天一
沈滨
毛建杰
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Abstract

The present invention provides a kind of drug and preparation method thereof for treating osteoproliferation and disc herniation.The drug includes the traditional Chinese medicine ingredients such as costus root, Beijing spurge root, meson, native copper, carbonized hair, radix notoginseng, Bulbus Allii Fistulosi, pangolin, borneol and Moschus, has good therapeutic effect for osteoproliferation and disc herniation.

Description

Treat the drug and preparation method thereof of osteoproliferation and disc herniation
Technical field
The present invention relates to the field of Chinese medicines more particularly to a kind of drug for treating osteoproliferation and disc herniation and its preparations Method.
Background technology
Osteoproliferation and the protrusion of the intervertebral disc are doctor trained in Western medicine name of disease, according to its clinical manifestation, are belonged to " rheumatism " of traditional Chinese medicine Scope, the obstructed query of " numbness " i.e. impatency is a kind of common disease of orthopaedics, and cardinal symptom is:Light then pain is uncomfortable, heavy then movable Inconvenience, the state of an illness is touching refractory, and patient feels pain deeply.
Osteoproliferation category traditional Chinese medicine numbness disease, severe and wadering arthralgia, pain in the back, goinyalgia, the scopes such as heumatism, mostly by kidney deficiency and liver, essence and blood loses Damage or chronic strain are affected by the cold, are damp and hot, qi depression to blood stasis causes.《Interior warp》Discuss earliest the pathogenic factor of disadvantage, the interpretation of the cause, onset and process of an illness and its Classification,《Plain Questions disadvantage》Cloud " wet three gas of chill is miscellaneous extremely, combined into numbness ".Modern medicine believes that, osteoproliferation refers to vertebra side Edge articular surface and apophysis source bone trabecula increase to be increased with bone density.Be again cause shape as lip or as beak, so also at For lip-like protrusion or spur, commonly referred to as spur.
The protrasion of the lumbar intervertebral disci is on the basis of retrogression pathological changes occur for lumber ertebral disc, because heavy burden or spinal motion make vertebra Disk is caused fibrous ring to destroy by acute or chronic damage, Nucleus pulposus, the surroundings group such as stimulation and pressuring neural root, blood vessel It knits, so as to cause using pain in waist and lower extremities as the illness of cardinal symptom.
With the quickening of daily life rhythm, the time that people take exercise in daily life is fewer and fewer, especially number The personnel of increasingly increased office work, due to keeping identical posture for a long time, and the chance of daily exercise is less, sclerotin The incidence probability of the illnesss such as hyperplasia and the protrusion of the intervertebral disc is also higher and higher.
However, currently, for cervical vertebra, protrusion of lumber intervertebral disc and osteoproliferation etc. there is no very effective therapy, Routine operation resets the methods of massage slowly effect, and has prodigious injury and side effect to human body, and disease often can also occur Pain recurs.
In view of this, special propose the present invention.
Invention content
The present invention provides a kind of drug, to treat osteoproliferation and disc herniation.
In order to achieve the above objectives, the drug of the embodiment of the present invention in parts by weight, including following components:Costus root 3- 10 parts, Beijing spurge root 7-12 parts, 15-25 parts of meson, 3-8 parts of native copper, 2-7 parts of carbonized hair, 6-15 parts of radix notoginseng, Bulbus Allii Fistulosi 30-60 Part, 3-10 parts of pangolin, 0.1-1 parts of borneol, 0.1-1 parts of Moschus.
Optionally, in parts by weight, the drug includes:4-9 parts of costus root, Beijing spurge root 8-14 parts, meson 16-24 Part, 4-7 parts of native copper, 3-6 parts of carbonized hair, 7-14 parts of radix notoginseng, 35-55 parts of Bulbus Allii Fistulosi, 4-9 parts of pangolin, borneol 0.2-0.9 Part, 0.2-0.9 parts of Moschus.
Optionally, in parts by weight, the drug includes:5-7 parts of costus root, Beijing spurge root 9-13 parts, meson 17-23 Part, 4-7 parts of native copper, 4-5 parts of carbonized hair, 8-13 parts of radix notoginseng, 40-50 parts of Bulbus Allii Fistulosi, 5-8 parts of pangolin, borneol 0.3-0.8 Part, 0.3-0.8 parts of Moschus
Another aspect of the present invention provides a kind of preparation method of drug above-mentioned comprising following steps:By costus root, capital The root of Beijing euphorbia, meson, native copper, carbonized hair, radix notoginseng, Bulbus Allii Fistulosi and pangolin are ground to pureed mixture;Borneol and Moschus are mixed and melted In the pureed mixture.
The drug of the embodiment of the present invention there is the knot analgesic that disappears, myogenic to dispel bitterly, promoting blood circulation and removing blood stasis, the effect of resolution.Wherein Drug ingedient be mostly that pungent-warm walks the product altered, have stronger penetration power.In place of sticking lesion, pore is promoted to open, blood capillary Enlargement of pipe, drug penetrate rapidly skin, and place, discharges pharmacodynamic feature completely from dermal absorption to lesion, reach warm eliminating evil bitterly, The stasis of blood is dissipated with tonneau, so that symptom is controlled or is disappeared, functional rehabilitation.
Specific implementation mode
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the invention.It is not specified in embodiment specific Condition person carries out according to conventional conditions or manufacturer's recommended conditions.Reagents or instruments used without specified manufacturer is The conventional products that can be obtained by commercially available purchase.
The embodiment of the present invention provides a kind of drug and preparation method thereof for treating osteoproliferation and disc herniation, presses According to parts by weight meter, the drug includes following components:3-10 parts of costus root, Beijing spurge root 7-12 parts, 15-25 parts of meson is natural 3-8 parts of copper, 2-7 parts of carbonized hair, 6-15 parts of radix notoginseng, 30-60 parts of Bulbus Allii Fistulosi, 3-10 parts of pangolin, 0.1-1 parts of borneol, Moschus 0.1-1 parts.
The pharmacology and nature,taste and action of ingredient used in the embodiment of the present invention:
Costus root:Warm-natured, pungent scattered temperature is logical, can disperse pathogenic cold in abdomen, the stagnant gas in row stomach and intestine, chest and abdomen one can be controlled by being good at regulating the qi flowing in the channels Cold obstruction causing qi stagnation is cut to have a pain.
Beijing spurge root:For drastically purgating water drug, external application here takes the work(of its dispersing swelling and dissipating binds, cure mainly heat toxin stop up it is stagnant, phlegm condensation gather it Otherwise severe takes its phase meaning with Radix Glycyrrhizae compatibility, increases high violent gesture, drug is made to go deep into osseous part.
Meson:Can warm lung slit phlegm profit gas, dissipating bind remove obstruction in channels to relieve pain, be mainly used for the stagnant channels and collaterals of phlegm, dissipating bind is removed obstruction in channels to relieve pain, joint fiber crops Wood, pain, cloudy subcutaneous ulcer pyogenic infections.
Native copper:There is the effect of scattered stasis of blood synthetism, analgesic, is mainly used for treating the diseases such as tumbling and swelling, injured bone.
Carbonized hair:Main five galleries, obstruction and rejection is obstructed, diuresis water channel, treats children's epilepsy, adult's convulsion.
Radix notoginseng:It can stop blooding, dissipate the stasis of blood, detumescence, analgesic therapy, be mainly used for strong waist knee, scattered stasis detumescence, waist and knee numbness pain, control bruise Damage, fracture.
Bulbus Allii Fistulosi:It is acrid in flavour and warm in nature;Return lung, stomach;Inducing sweat and dispelling exogenous evils, suitable for the mild case caught cold;Sensible yang-energy, can be used for cold sensation of the genitalia Interior Sheng, refusing yang are fainted inverse in outer, weak pulse.
Pangolin:Warm-natured cold, property is apt to walk to alter, and the special row of work(dissipates interior logical internal organs, and outer channels and collaterals have detumescence effect.
Borneol:Borneol fragrance is walked to alter, and osmosis is strong, can all medicines of rate guide drugs to illness station.
Moschus:The secretion of glandular sac between the navel and genitals of male musk deer is in granular form or blocky after dry, there is spy Different fragrance, there is bitter taste, and fragrance can be made, and can also be used as medicine;It is central nervous excitation agent, external application can ease pain, subside a swelling;For Blood stasis, note of the ancient Chinese lump in the abdomen, trusted subordinate sudden and violent pain, traumatic injury, the cards such as wind-cold-dampness arthralgia;The pungent perfume (or spice) of the product, opens away and alters, the stasis of blood that can be in promoting circulation of blood Stagnant, the heap soil or fertilizer over and around the roots for opening channels and collaterals is held back, and is used for sore swollen toxin, abscess of throat with promoting menstruation eliminating stagnation to stop pain, the pungent fragrant row of the product dissipates, and has good promoting blood circulation Dissipating bind, swelling and pain relieving effect, takes orally, external application has good effect.
Preferably, according to weight fraction meter, each component dosage of the drug of the embodiment of the present invention can be as follows:Costus root 4- 9 parts, such as can be, but it is not limited to 5,6,7 or 8 parts etc.;Beijing spurge root 8-14 parts, such as can be, but be not limited to 9,10, 11,12 or 13 parts;16-24 parts of meson, such as can be, but it is not limited to 17,18,19,20,21,22 or 23 parts;Native copper 4-7 Part, such as can be, but it is not limited to 5 or 6 parts;3-6 parts of carbonized hair, such as can be, but it is not limited to 4 or 5 parts;Radix notoginseng 7-14 Part, such as can be, but it is not limited to 8,9,10,11,12 or 13 parts;35-55 parts of Bulbus Allii Fistulosi for example can be, but be not limited to 40, 45,50 parts;4-9 parts of pangolin for example can be, but be not limited to 5,6,7 or 8 parts;0.2-0.9 parts of borneol, such as can be, but It is not limited to 0.3,0.4,0.5,0.6,0.7,0.8 part;0.2-0.9 parts of Moschus, such as can be, but be not limited to 0.3,0.4,0.5, 0.6,0.7,0.8 part.
The preparation method of the drug of the embodiment of the present invention includes the following steps:By costus root, Beijing spurge root, meson, native copper, Carbonized hair, radix notoginseng, Bulbus Allii Fistulosi and pangolin are ground to pureed mixture;Borneol and Moschus are mixed and melted in the pureed mixture In, form pasta medicine for external application.
The drug of the embodiment of the present invention there is the knot analgesic that disappears, myogenic to dispel bitterly, promoting blood circulation and removing blood stasis, the effect of resolution.Wherein Drug ingedient be mostly that pungent-warm walks the product altered, have stronger penetration power.In place of sticking lesion, pore is promoted to open, blood capillary Enlargement of pipe, drug penetrate rapidly skin, and place, discharges pharmacodynamic feature completely from dermal absorption to lesion, reach warm eliminating evil bitterly, The stasis of blood is dissipated with tonneau, so that symptom is controlled or is disappeared, functional rehabilitation.
Embodiment one:
According to weight grams, 3 grams of costus root, 7 grams of Beijing spurge root, 20 grams of meson, 3 grams of native copper, 7 grams of carbonized hair, ginseng three are taken 76 grams, 30 grams of Bulbus Allii Fistulosi, 10 grams of pangolin, 0.1 gram of borneol, 0.1 gram of Moschus.
Then according to above-mentioned grams ratio by costus root, Beijing spurge root, meson, native copper, carbonized hair, radix notoginseng, Bulbus Allii Fistulosi and Pangolin is ground to pureed mixture;Borneol and Moschus are mixed and melted in the pureed mixture, pasta medicine for external application is formed.
Embodiment two:
According to weight grams, 10 grams of costus root, 9 grams of Beijing spurge root, 25 grams of meson, 3 grams of native copper, 2 grams of carbonized hair, ginseng three are taken 76 grams, 60 grams of Bulbus Allii Fistulosi, 10 grams of pangolin, 1 gram of borneol, 1 gram of Moschus.
Then according to above-mentioned grams ratio by costus root, Beijing spurge root, meson, native copper, carbonized hair, radix notoginseng, Bulbus Allii Fistulosi and Pangolin is ground to pureed mixture;Borneol and Moschus are mixed and melted in the pureed mixture, pasta medicine for external application is formed.
Embodiment three:
According to weight grams, 4 grams of costus root, 9 grams of Beijing spurge root, 18 grams of meson, 7 grams of native copper, 6 grams of carbonized hair, ginseng three are taken 7 13 grams, 50 grams of Bulbus Allii Fistulosi, 7 grams of pangolin, 0.6 gram of borneol, 0.5 gram of Moschus.
Then according to above-mentioned grams ratio by costus root, Beijing spurge root, meson, native copper, carbonized hair, radix notoginseng, Bulbus Allii Fistulosi and Pangolin is ground to pureed mixture;Borneol and Moschus are mixed and melted in the pureed mixture, pasta medicine for external application is formed.
Example IV:
According to weight grams, 6 grams of costus root, 11 grams of Beijing spurge root, 16 grams of meson, 7 grams of native copper, 3 grams of carbonized hair, ginseng three are taken 7 14 grams, 45 grams of Bulbus Allii Fistulosi, 9 grams of pangolin, 0.3 gram of borneol, 0.8 gram of Moschus.
Then according to above-mentioned grams ratio by costus root, Beijing spurge root, meson, native copper, carbonized hair, radix notoginseng, Bulbus Allii Fistulosi and Pangolin is ground to pureed mixture;Borneol and Moschus are mixed and melted in the pureed mixture, pasta medicine for external application is formed.
Embodiment five:
According to weight grams, 4 grams of costus root, 9 grams of Beijing spurge root, 18 grams of meson, 7 grams of native copper, 6 grams of carbonized hair, ginseng three are taken 7 13 grams, 50 grams of Bulbus Allii Fistulosi, 7 grams of pangolin, 0.6 gram of borneol, 0.5 gram of Moschus.
Then according to above-mentioned grams ratio by costus root, Beijing spurge root, meson, native copper, carbonized hair, radix notoginseng, Bulbus Allii Fistulosi and Pangolin is ground to pureed mixture;Borneol and Moschus are mixed and melted in the pureed mixture, pasta medicine for external application is formed.
It is more than thousand to use the patient of the plaster treatment of the medicine preparation of the embodiment of the present invention for many years, by patient Observation, understanding, pay a return visit summarize, it is known that:The important composition of the embodiment of the present invention is for osteoproliferation, the protrusion of the intervertebral disc Treated effect is up to 90% or more, 80% or more cure rate.
Treat the clinical statistics of osteoproliferation:
Male 453 people, 378 people of female;40 years old or more 652, the oldest 86 years old, minimum 20 years old.Wherein lumbar vertebrae hyperosteogeny 633 people, 521 people of cervical vertebrae hyperosteogeny, 133 people of articulatio genus hyperosteogeny, 67 people of hyperosteogeny.All make film through x-ray, CT It makes a definite diagnosis.Longest 30 years of the course of disease in patient, shortest 1 month, 85% controlled by traction, massage, drug injection and oral drugs It treats or even operative treatment is invalid or effect unobvious.
The effect for the treatment of:
723 people, cure rate 87%, effective percentage 94%, inefficiency 6% are cured in 831 middle-older patients.90% patient It is not recurred for a long time after healing.40 years old 179 people of patient below cure 163 people, cure rate 91%, effective percentage 96%, inefficiency 4%.
There are 12 and with the protrasion of the lumbar intervertebral disci and patient of lower limb paralysis cures, freedom of movement is taken care of oneself.
Treat the clinical statistics of disc herniation:
Male 572 people, 431 people of female, 18-40 Sui accounts for 32%, and 40 years old or more is common.Wherein 683 people of protrusion of lumber intervertebral disc, neck 320 people of disc herniation.Patient makes a definite diagnosis through the film making of x-ray, CT and nuclear-magnetism, and 80% is undesirable by a variety of method therapeutic effects, 20 people did intervertebral disc operation treatment and recurred again.
The effect for the treatment of:
40 years old or more 672 people of patient, 401 people of male, healing 353, cure rate 88%, effective percentage 97%, inefficiency 3%. 271 people of women cures 247 people, cure rate 92%, effective percentage 96%, inefficiency 4%.Protrusion of lumber intervertebral disc patient 683 rules by men more 608 people, cure rate 89%, effective percentage 97%, inefficiency 3%.Cervical Disk Herniation patient 320 rules more 285 people, cure rate by men 89%, effective percentage 96%, inefficiency 4%.
Treatment observation is characterized as:
One, the treatment of osteoproliferation
It cures:Osteoproliferation position nerve is no longer pressurized, and inflammation disappears, and limbs pain disappears.
Effectively:Hyperplasia position inflammation is substantially reduced, and limbs pain mitigates.
In vain:Not up to above-mentioned standard, hyperplasia position inflammation and limbs pain do not mitigate as invalid.
Two, the treatment of disc herniation
It cures:The nerve root inflammation at disc herniation position disappears, and interverbebral disc sets back, and damaged fibrous ring is repaiied Multiple, limbs pain disappears.
Effectively:Though above-mentioned standard not fully achieved, limbs pain sense is substantially reduced.
In vain:Still not up to above-mentioned standard person is as invalid after treating two courses for the treatment of.
The drug for the treatment of osteoproliferation and disc herniation that the embodiment of the present invention is provided has through the clinical application of more than 10 years Following advantages:
One, since basic Chinese medicine used by the embodiment of the present invention only has ten kinds, and the preparation process of medicament is more simple It is single, therefore have the advantages that cost is inexpensive, and the number that patient uses is few, it is quick, can be greatly reduced the treatment of patient at This.
Two, there is short treating period, high efficiency and eutherapeutic excellent using the medicinal ointment therapy osteoproliferation, disc herniation Point.
Three, the medical ointment plaster method is simple and convenient, and ointment need to only be applied to paste on stype and use by patient, and uninterrupted medication is It can.It is not required to be hospitalized, and stops other treatment method.
Four, since the ointment is all formed by Chinese herbal medicine compatibility, and to be applied with, there is nontoxic nothing compared with using Western medicine The advantages of side effect.
Model case:The drug of embodiment 1-5 is respectively used to treatment osteoproliferation, Cervical Disk Herniation and waist respectively Disc herniation patient;
1, patient's section certain, man, 76 years old, CT reported waist 5 sacrum 1 disc herniation, waist 4-5 osteoproliferations, pain of bending on foot Unbearably, after the plaster that the drug that five lose money in a business inventive embodiments one makes has been pasted at Lesional Skin, symptom disappears, not multiple so far Hair.
2, patient Huang, female, 59 years old, CT reported that waist 4-5,5-6 osteoproliferation, paxwax calcification, Symptoms are headache Hand is numb, eye-blurred, and after the plaster that the rear drug for losing money in a business inventive embodiments one with 6 makes, symptom is obviously improved, headache hand fiber crops, Eye-blurred symptom is greatly alleviated.
3, patient Cao, man, 57 years old, CT reported protrusion of lumber intervertebral disc and each lumbar vertebrae hyperosteogeny, and both legs are numb, walking Difficulty, after the plaster that the rear drug for losing money in a business inventive embodiments two with 10 makes, symptom disappearance is not recurred so far.
4, patient Sun, female, 50 years old, because of flank pain, limitation of activity etc., lumber ertebral disc CT showed waist 4-5 and 5 rumpbone of waist Matter hyperplasia, protrusion of lumber intervertebral disc seriously affect life, and the plaster that the rear drug for losing money in a business embodiment three with 5 makes, pain in the back disappears, Waist activity is good, checks waist and sacral CT shows that waist 4-5 and 5 sacrum of waist, disc herniation are obviously improved;Then using 6 patches, disease Shape disappears, and does not recur.
5, patient Lee, female, 35 years old, be in discontinuity, Changes in weather and labor because of the sour swollen and dizziness and nausea of neck, inability Symptom obviously aggravates after tired, after the plaster made of the drug of the embodiment of the present invention four has continuously pasted 4 patches, does not up to the present have Feeling of pain.
6, patient's week certain, man, 53 years old, cervical vertebra stiffness and knee joint swelling and pain made of the drug of the embodiment of the present invention five After plaster has continuously pasted 5 patches, symptom disappears, and more than 3 years so far in recall pain.
By the Experiment on therapy result of upper table it is found that drug of the present invention is for osteoproliferation, Cervical Disk Herniation and lumbar vertebrae Disk protrusion has good therapeutic effect.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.

Claims (4)

1. a kind of drug for treating osteoproliferation and disc herniation, it is characterised in that:In parts by weight, the drug packet Include following components:3-10 parts of costus root, Beijing spurge root 7-12 parts, 15-25 parts of meson, 3-8 parts of native copper, 2-7 parts of carbonized hair, ginseng three Seven 6-15 parts, 30-60 parts of Bulbus Allii Fistulosi, 3-10 parts of pangolin, 0.1-1 parts of borneol, 0.1-1 parts of Moschus.
2. drug according to claim 3, which is characterized in that in parts by weight, the drug includes:Costus root 4- 9 parts, Beijing spurge root 8-14 parts, 16-24 parts of meson, 4-7 parts of native copper, 3-6 parts of carbonized hair, 7-14 parts of radix notoginseng, Bulbus Allii Fistulosi 35-55 Part, 4-9 parts of pangolin, 0.2-0.9 parts of borneol, 0.2-0.9 parts of Moschus.
3. drug according to claim 1, which is characterized in that in parts by weight, the drug includes:Costus root 5- 7 parts, Beijing spurge root 9-13 parts, 17-23 parts of meson, 4-7 parts of native copper, 4-5 parts of carbonized hair, 8-13 parts of radix notoginseng, Bulbus Allii Fistulosi 40-50 Part, 5-8 parts of pangolin, 0.3-0.8 parts of borneol, 0.3-0.8 parts of Moschus.
4. a kind of preparation method of drug as claimed in any one of claims 1-3 comprising following steps:
Costus root, Beijing spurge root, meson, native copper, carbonized hair, radix notoginseng, Bulbus Allii Fistulosi and pangolin are ground to pureed mixture;
Borneol and Moschus are mixed and melted in the pureed mixture.
CN201810336253.4A 2018-04-16 2018-04-16 Treat the drug and preparation method thereof of osteoproliferation and disc herniation Pending CN108310185A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1775236A (en) * 2005-11-16 2006-05-24 石昆山 Ointment for treating hyperosteogeny and intervertebral disc protrusion and preparation method thereof
CN1840053A (en) * 2006-01-20 2006-10-04 唐印乔 Medicine for treating arthritis, hyperosteogeny and intervertebral disc protrusion and preparation process thereof
CN100998823A (en) * 2006-01-13 2007-07-18 程永军 Plaster for treating osteosis, protrasion of lumbar intervertebral disc

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1775236A (en) * 2005-11-16 2006-05-24 石昆山 Ointment for treating hyperosteogeny and intervertebral disc protrusion and preparation method thereof
CN100998823A (en) * 2006-01-13 2007-07-18 程永军 Plaster for treating osteosis, protrasion of lumbar intervertebral disc
CN1840053A (en) * 2006-01-20 2006-10-04 唐印乔 Medicine for treating arthritis, hyperosteogeny and intervertebral disc protrusion and preparation process thereof

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Application publication date: 20180724