CN114949145A - Swelling-dispersing pain-relieving powder and preparation method thereof - Google Patents

Swelling-dispersing pain-relieving powder and preparation method thereof Download PDF

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CN114949145A
CN114949145A CN202210639484.9A CN202210639484A CN114949145A CN 114949145 A CN114949145 A CN 114949145A CN 202210639484 A CN202210639484 A CN 202210639484A CN 114949145 A CN114949145 A CN 114949145A
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parts
pain
swelling
powder
relieving
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张北军
郑宗敬
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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Abstract

The invention discloses swelling-diminishing and pain-relieving powder and a preparation method thereof, wherein the swelling-diminishing and pain-relieving powder is prepared from the following raw materials in parts by weight: 1-3 parts of rhubarb, 3-5 parts of turmeric, 2-3 parts of gardenia, 3-5 parts of pawpaw, 3-5 parts of dandelion and 5-8 parts of phellodendron. Has the advantages that: the formula disclosed by the invention has good skin affinity, can generate anaphylactic reaction for few patients, and has remarkable swelling and pain relieving effects on traumatic injury, soft tissue injury swelling and pain, gout arthritis swelling and pain, tendon sheath edema and bone marrow edema.

Description

Swelling-dispersing pain-relieving powder and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to swelling-diminishing and pain-relieving powder and a preparation method thereof.
Background
At present, although a lot of medicines for relieving swelling and pain exist, the treatment effect is not ideal mostly, some oral medicines have great side effect, some external medicines have unpleasant smell, and other external medicines have irritation to the skin. For example, some external liquid medicines only have the effect of relieving pain for a short time, and can treat the exterior and do not treat the root cause; some oral medicines not only have slow speed of detumescence and acesodyne, but also have side effects of damaging liver and kidney. In addition, some external drugs can cause adverse reactions such as skin allergy and the like after being used for a long time.
Disclosure of Invention
The invention aims to solve the problems and provide swelling-diminishing and pain-relieving powder and a preparation method thereof.
The invention realizes the purpose through the following technical scheme:
the swelling-diminishing and pain-relieving powder consists of the following raw materials in parts by weight: 1-3 parts of rhubarb, 3-5 parts of turmeric, 2-3 parts of gardenia, 3-5 parts of pawpaw, 3-5 parts of dandelion and 5-8 parts of phellodendron.
Preferably, the composition is prepared from the following raw materials in parts by weight: 1 part of rhubarb, 4 parts of turmeric, 2 parts of gardenia, 4 parts of pawpaw, 4 parts of dandelion and 6 parts of phellodendron.
Preferably, the composition is prepared from the following raw materials in parts by weight: 3 parts of rhubarb, 3 parts of turmeric, 3 parts of gardenia, 3 parts of pawpaw, 3 parts of dandelion and 8 parts of phellodendron.
Preferably, the composition is prepared from the following raw materials in parts by weight: 2 parts of rhubarb, 5 parts of turmeric, 2 parts of gardenia, 5 parts of pawpaw, 5 parts of dandelion and 5 parts of phellodendron.
The invention also provides a preparation method for producing the swelling-diminishing and pain-relieving powder, which comprises the following steps:
a. weighing the rhubarb, the turmeric, the gardenia, the pawpaw, the dandelion and the phellodendron according to the weight parts, and respectively grinding into fine powder;
b. mixing radix et rhizoma Rhei fine powder, Curcuma rhizome fine powder, fructus Gardeniae fine powder, fructus Chaenomelis fine powder, herba Taraxaci fine powder and cortex Phellodendri fine powder to obtain the final product.
The medicine properties of the medicine are as follows:
rhubarb: bitter taste and cold nature; spleen, stomach, large intestine, liver, heart meridian entered; the efficacy is as follows: has effects in purging pathogenic accumulation, clearing away heat, purging pathogenic fire, cooling blood, removing toxic materials, dispelling blood stasis, dredging channels, promoting diuresis, and eliminating jaundice; the main treatment is as follows: can be used for treating constipation due to excessive heat accumulation, hematemesis, epistaxis, conjunctival congestion, pharyngeal swelling, carbuncle, sore, intestinal carbuncle, abdominal pain, blood stasis, amenorrhea, puerperal blood stasis, traumatic injury, damp-heat dysentery, jaundice, dark urine, stranguria, and edema; externally treating burns and scalds;
turmeric: pungent and bitter taste, warm nature; entering liver and spleen meridians; the efficacy is as follows: breaking blood and moving qi, inducing menstruation and alleviating pain, the main indications are: the pungent and pungent turmeric can disperse warmly, dredge bitter, enter the blood system and the qi system, can activate blood, promote qi circulation and relieve pain, can treat chest and chest pain caused by the failure of chest yang and the blockage of heart and vessels, can also be used for treating chest and hypochondriac pain caused by qi stagnation of liver and stomach and congealing cold, or dysmenorrhea, amenorrhea and postpartum abdominal pain caused by qi stagnation and blood stasis, can also be used for treating traumatic injury, stasis and swelling pain, and in addition, the turmeric can disperse warmly and pungent, bitter, warm and dredge, externally disperse wind cold and damp evil, internally circulate qi and blood, dredge channels and relieve pain, and can be used for treating rheumatic arthralgia;
gardenia: bitter and cold in property, non-toxic, entering heart, lung, stomach and triple energizer meridians, and mainly functions: purging pathogenic fire, relieving restlessness, clearing away heat, promoting urination, cooling blood, and removing toxic substances; can be used for treating pyretic vexation, depression, restlessness, damp-heat stagnation, jaundice, oliguria with reddish urine, hematemesis due to excessive heat and toxic heat, epistaxis, hematuria, carbuncle, conjunctival congestion, swelling and pain, and pyocutaneous disease and furuncle; sprain, contusion and pain in external use; charred fructus Gardeniae has effects in cooling blood and stopping bleeding, and can be used for treating hematemesis, epistaxis, hematuria, metrorrhagia and metrostaxis;
pawpaw: sour and warm; entering liver and spleen; the functional indications are as follows: relaxing muscles and tendons, activating collateral flow, regulating stomach function, and eliminating dampness; used for treating damp arthralgia and spasm; soreness, heaviness and pain of the waist and knee joints; vomiting and diarrhea due to summer-heat dampness, spasm and pain of tendon, beriberi and edema;
dandelion: bitter and sweet, cold and entering liver and stomach meridians, mainly functions: clearing away heat and toxic materials, inducing diuresis, and resolving hard mass, and can be used for treating acute mastitis, lymphadenitis, lymphoid tuberculosis, furunculosis, acute conjunctivitis, common cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, and urinary tract infection;
phellodendron bark: bitter in taste and cold in nature, entering kidney meridian; the bladder; the large intestine channel, the functional indications are: clearing heat and detoxicating, purging pathogenic fire and eliminating dampness, and can be used for treating acute bacillary dysentery, acute enteritis, acute icteric hepatitis, urinary system infection, etc., and for treating fire scald, otitis media, acute conjunctivitis, etc. by external application.
The invention has the beneficial effects that:
the formula disclosed by the invention has good skin affinity, can generate anaphylactic reaction for few patients, and has remarkable swelling and pain relieving effects on traumatic injury, soft tissue injury swelling and pain, gout arthritis swelling and pain, tendon sheath edema and bone marrow edema.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows:
the swelling-diminishing and pain-relieving powder consists of the following raw materials in parts by weight: 1 part of rhubarb, 4 parts of turmeric, 2 parts of gardenia, 4 parts of pawpaw, 4 parts of dandelion and 6 parts of phellodendron.
Example two:
the swelling-diminishing and pain-relieving powder consists of the following raw materials in parts by weight: 3 parts of rhubarb, 3 parts of turmeric, 3 parts of gardenia, 3 parts of pawpaw, 3 parts of dandelion and 8 parts of phellodendron.
Example three:
2 parts of rhubarb, 5 parts of turmeric, 2 parts of gardenia, 5 parts of pawpaw, 5 parts of dandelion and 5 parts of phellodendron.
A preparation method for producing the swelling-dispersing and pain-relieving powder comprises the following steps:
a. weighing the rhubarb, the turmeric, the gardenia, the pawpaw, the dandelion and the phellodendron according to the weight parts, and respectively grinding into fine powder;
b. is prepared from radix et rhizoma Rhei fine powder, Curcuma rhizome fine powder, fructus Gardeniae fine powder, fructus Chaenomelis fine powder, herba Taraxaci fine powder and cortex Phellodendri fine powder.
The using method comprises the following steps: according to the following steps: 0.5, mixing the fine powder with normal saline uniformly, and carrying out external application by covering the affected part with the mixture according to the area of the affected part, wherein the change is carried out for 1 time every 24 hours.
Example one prepared drug application example 1:
in any certain patient, the female is aged 76 years, the left ankle joint is painful for more than 20 days, the patient is examined by a traditional Chinese medical hospital in county of 2022 years, 5 months and 23 days, the traditional Chinese medical hospital is in a way of going to mountain, the patient has no obvious inducement before more than 20 days, the left ankle joint is painful, the patient slightly swells, the skin color is normal, the left ankle joint continuously attacks, the pain is difficult to endure in sitting, standing, lying and walking, the pain is even, the pain is relieved by using a pain relieving suppository, the patient is still in the mental state, the sleep is not good, the diet is not good, the patient mainly eats food, the nocturia frequency is frequent, the patient is constipation, the physical body weight is not obviously reduced, and the western medicine is identified and diagnosed: the medicinal powder is applied to acupuncture points, namely Kunlun, Shenmai, Taixi and Canhai 4 acupuncture points each time, the pain of the left ankle joint of a patient is obviously relieved before the examination of the next day, the swelling is eliminated, the skin color is normal, and the pain of the left ankle joint disappears after two days of application.
Application example 2:
Wu-Chi, women, age 54, neck and shoulder pain, lumbago for more than 10 days, pain in the shoulder joints and limited activity at the left nowadays, and no obvious relief of the rest symptoms at home, the doctor in Laitong county in 2022 years needs to be recovered after treatment in 12 days 05 and 5 and 14 days, the medicinal powder is adopted for acupoint application treatment: four acupuncture points of the cervical root, the shoulder well, the Jianyu and the arm Binao are taken once a day, the left shoulder pain is relieved after examination for 5 and 17 days, the motion range of the left shoulder joint is enlarged, then the four acupuncture points are continuously pasted for treatment, and the pain disappears after 3 days.
Application example 3:
in summer, a woman is 80 years old, lumbago caused by double lower limbs and intermittent attack are caused by patients without obvious reasons before 4 years, lumbar intervertebral disc foramen operation treatment is performed once, the symptoms of the patients before 22 months at 4 months at 2022 are aggravated again with back pain and severe pain of the double lower limbs, the pain at the inner sides of the double knee joints is obvious, foot numbness and continuous attack are caused, the patients cannot walk for a long distance, the patients must rest and walk after walking for about 40-50 meters, pain at night is waken, intolerance of cold, fever, abdominal pain, diarrhea, pain in urine, edema and the like, daily life is seriously affected, the patients are diagnosed in Shanshan county in a hospital in 28 days in 4 months, the medicinal powder is applied to the patients after 4 days in 5 months, 8 acupuncture points of 11 ridges (double), aspiration chambers (right), ideo (right), inner knee eyes (double), and crane tops (double) are applied to the medicine once a month in 5-15 days, the patients have obvious improvement of the back pain before the pain every day, the pain of waist and double knee joints is relieved earlier, and then the acupoint application treatment is continued, 8 acupoints of waist 5/sacrum 1 (double), Dachangshu (double), inner knee eye (double) and Crane crown (double) are applied with the medicine, once a day, after 6 days, the pain of waist and double knee joints of the patient disappears, and the patient is discharged.
Application example 4:
the traditional Chinese medicine is examined by a traditional Chinese medicine hospital in Xuan Yi, a woman, 75 years old, 2022 years old, 5 months and 4 days to Tongshan county, and has no obvious induction of sudden onset of lumbar pain, 3-day aggravation, accompanying hip pain, difficult stooping and turning over, difficult pain feeling in sitting, standing and walking, no relief of physical therapy treatment symptoms in a private clinic and western medicine diagnosis: bone marrow edema, chest 12 vertebral body compression fracture, lumbar spondylolisthesis, low-frequency pulse electrical therapy, medium-frequency pulse electrical therapy, traditional Chinese medicine oriented drug delivery therapy and low-frequency pulse electrical therapy part treatment are adopted from 5 months to 5 months 17 days, but the patient feels no obvious improvement of the pain of the waist and the back, the spirit is normal, the patient takes the medicine powder for pasting treatment in 5 months 17 days, the 4 points of the Shu vesicae, the Shenshu, the Dachangshu and the triple energizer are pasted with the medicine, the inspection is carried out again for 1 time every day, 20 months and 20 days, the patient feels the pain of the waist and the back obviously improved earlier, the walking is easy, the spirit is normal, the diet is normal, other discomforts are not mentioned, the vital signs are stable, the medicine powder is continuously adopted for pasting treatment in the 4 points of the Shu vesicae, the Shenshu, the big changshu and the triple energizer for 5 months 30 days, the pain of the waist and the patient is discharged from a hospital.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed.

Claims (5)

1. The swelling-diminishing and pain-relieving powder is characterized in that: the composition is characterized by comprising the following raw materials in parts by weight: 1-3 parts of rhubarb, 3-5 parts of turmeric, 2-3 parts of gardenia, 3-5 parts of pawpaw, 3-5 parts of dandelion and 5-8 parts of phellodendron.
2. The swelling-reducing and pain-relieving powder as claimed in claim 1, which is characterized in that: the composition is characterized by comprising the following raw materials in parts by weight: 1 part of rhubarb, 4 parts of turmeric, 2 parts of gardenia, 4 parts of pawpaw, 4 parts of dandelion and 6 parts of phellodendron.
3. The swelling-reducing and pain-relieving powder as claimed in claim 1, which is characterized in that: the composition is characterized by comprising the following raw materials in parts by weight: 3 parts of rhubarb, 3 parts of turmeric, 3 parts of gardenia, 3 parts of pawpaw, 3 parts of dandelion and 8 parts of phellodendron.
4. The swelling-reducing and pain-relieving powder as claimed in claim 1, which is characterized in that: the composition is characterized by comprising the following raw materials in parts by weight: 2 parts of rhubarb, 5 parts of turmeric, 2 parts of gardenia, 5 parts of pawpaw, 5 parts of dandelion and 5 parts of phellodendron.
5. The process for preparing the swelling-dispersing and pain-relieving powder as claimed in any one of claims 1 to 4, is characterized in that: the method comprises the following steps:
a. weighing the rhubarb, the turmeric, the gardenia, the pawpaw, the dandelion and the phellodendron according to the weight parts, and respectively grinding into fine powder;
b. mixing radix et rhizoma Rhei fine powder, Curcuma rhizome fine powder, fructus Gardeniae fine powder, fructus Chaenomelis fine powder, herba Taraxaci fine powder and cortex Phellodendri fine powder to obtain the final product.
CN202210639484.9A 2022-06-08 2022-06-08 Swelling-dispersing pain-relieving powder and preparation method thereof Pending CN114949145A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432516A (en) * 2013-08-12 2013-12-11 刘斌 Plaster capable of eliminating stasis, activating collaterals and relieving pain and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103432516A (en) * 2013-08-12 2013-12-11 刘斌 Plaster capable of eliminating stasis, activating collaterals and relieving pain and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王德军: "四妙散加味配合消肿散外敷治疗痛风性关节炎的临床研究" *

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Application publication date: 20220830

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