CN112022916A - Traditional Chinese medicine composition and preparation for treating postpartum body pain and preparation method and application thereof - Google Patents
Traditional Chinese medicine composition and preparation for treating postpartum body pain and preparation method and application thereof Download PDFInfo
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- CN112022916A CN112022916A CN202011092056.6A CN202011092056A CN112022916A CN 112022916 A CN112022916 A CN 112022916A CN 202011092056 A CN202011092056 A CN 202011092056A CN 112022916 A CN112022916 A CN 112022916A
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Abstract
The invention provides a traditional Chinese medicine composition for treating postpartum body pain, which comprises, by weight, 10-20 parts of raw astragalus membranaceus, 5-15 parts of cooked monkshood, 15-25 parts of cinnamon, 5-15 parts of cassia twig, 10-20 parts of morinda officinalis, 10-20 parts of angelica sinensis, 15-25 parts of caulis spatholobi, 15-25 parts of spina date seeds, 10-20 parts of schizonepeta, 10-20 parts of radix angelicae pubescentis, 10-20 parts of notopterygium roots, 10-20 parts of folium artemisiae argyi, 10-20 parts of ramulus mori, 10-20 parts of parasitic loranthus, 15-25 parts of radix puerariae, 5-15 parts of frankincense and 10-20 parts of myrrh. The invention also provides a traditional Chinese medicine decoction prepared from the traditional Chinese medicine composition and a preparation method; and the application of the Chinese medicinal composition in preparing medicaments for treating postpartum pain of body, postpartum arthralgia, postpartum headache or postpartum cold.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating postpartum body pain, a preparation method and application thereof.
Background
Postpartum general pain occurs in puerperium, and is usually manifested as soreness, pain, and heaviness of limbs or joints. The investigation shows that the body pain rate of the patient in the puerperium is higher, and the patient has sudden characteristics and is unfavorable for the physical and mental health of the patient. If the patient does not see a doctor in time, the patient cannot receive scientific and effective treatment, and the patient is difficult to self-heal under normal conditions. At present, western medicine lacks a specific therapy for the disease, but the traditional Chinese medicine treatment has a long history of postpartum body pain, has the advantages of good curative effect, high safety and the like, and can improve the disease after scientific treatment of most patients.
In addition, female patients often have high requirements on self body shapes, but pregnancy and childbirth can not avoid the increase of the body mass and the change of the body shape of the female, and if the women do not carry out scientific body shape recovery in time after delivery, the recovery of body building shapes is not facilitated, and a plurality of health problems can be caused. Therefore, postpartum recovery of body is important and necessary.
The Chinese patent application with the application number of CN201610144830.0 discloses an external washing medicine for treating postpartum external rheumatism, which comprises the following components: 30 parts of astragalus membranaceus, 30 parts of schizonepeta, 30 parts of mulberry twigs, 30 parts of pine segments, 30 parts of garlic stems, 30 parts of cassia twig, 30 parts of dried ginger, 20 parts of notopterygium roots, 20 parts of root of sanguineous, 20 parts of cinnamon, 15 parts of ligusticum wallichii, 15 parts of radix cyathulae and 30 parts of wormwood; the inventor claims that the traditional Chinese medicine can warm channel and dispel cold, promote blood circulation and remove meridian obstruction, and tonify qi and expel wind; is suitable for induced abortion and postpartum, and can effectively prevent puerperal diseases, repair birth canal, promote uterine contraction and promote lochia discharge; enhancing immunity, preventing invasion of exogenous pathogenic factors, relieving fatigue, promoting physical strength recovery of parturient, preventing gynecological diseases, preventing common cold, promoting health, and strengthening body constitution. But the treatment effect is poor, so that the problems of body pain and vaginal bleeding cannot be obviously improved on one hand; on the other hand, the body shape recovery of the lying-in woman basically has no improvement effect, and a plurality of problems are brought to the body shape recovery and the health of the lying-in woman.
Disclosure of Invention
The first purpose of the invention is to provide a traditional Chinese medicine composition for treating postpartum body pain, which can remarkably relieve pain of patients, regulate serum pain medium, clear and activate the channels and collaterals, regulate qi and blood and contribute to improvement of hemodynamics.
The second purpose of the invention is to provide a preparation method, application and use method of a traditional Chinese medicine decoction for treating postpartum body pain, which can exert the drug effect to the maximum extent and improve the positive effect of the efficacy of postpartum body pain.
The embodiment of the invention is realized by the following technical scheme:
a traditional Chinese medicine composition for treating postpartum pain of body comprises, by weight, 10-20 parts of raw astragalus membranaceus, 5-15 parts of cooked monkshood, 15-25 parts of cinnamon, 5-15 parts of cassia twig, 10-20 parts of morinda officinalis, 10-20 parts of angelica sinensis, 15-25 parts of caulis spatholobi, 15-25 parts of spina date seeds, 10-20 parts of schizonepeta, 10-20 parts of radix angelicae pubescentis, 10-20 parts of notopterygium roots, 10-20 parts of folium artemisiae argyi, 10-20 parts of ramulus mori, 10-20 parts of parasitic loranthus, 15-25 parts of radix puerariae, 5-15 parts of frankincense and 10-20 parts of myrrh.
An application of a Chinese medicinal composition in preparing medicine for treating puerperal pain of body, puerperal arthralgia, puerperal headache, and puerperal cold is provided.
A preparation prepared from a traditional Chinese medicine composition for treating postpartum body pain comprises the traditional Chinese medicine composition and pharmaceutically acceptable auxiliary materials.
Furthermore, the preparation is in the form of any one of decoction, powder and paste; preferably a decoction.
A preparation method of a traditional Chinese medicine decoction for treating postpartum body pain comprises the following steps: weighing the components according to the proportion, cleaning, crushing, and soaking in water for 10-30 minutes; decocting with slow fire after boiling, filtering, and cooling to obtain Chinese medicinal decoction.
A method for using Chinese medicinal decoction comprises selecting rectangular region from lumbar vertebra to back Shu line, 10cm on both sides of the posterior midline as fumigation part, and bathing and fumigating for 1 time per day with Chinese medicinal decoction.
The technical scheme of the embodiment of the invention at least has the following advantages and beneficial effects:
1. the components in the traditional Chinese medicine composition have synergistic effect, and the traditional Chinese medicine composition has the effects of warming and activating yang, nourishing yin and blood, and dispelling wind and cold, and is suitable for symptoms such as postpartum headache, aching muscles of trunk and limbs and the like.
2. The decoction prepared from the traditional Chinese medicine composition provided by the invention can remarkably relieve pain of patients, regulate serum pain medium, dredge meridian passage, regulate qi and blood, and is beneficial to improvement of hemodynamics.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
The following specifically describes the traditional Chinese medicine composition and the traditional Chinese medicine decoction for treating postpartum body pain, the preparation method, the use method and the application thereof provided by the embodiment of the invention.
A traditional Chinese medicine composition for treating postpartum pain of body comprises, by weight, 10-20 parts of raw astragalus membranaceus, 5-15 parts of cooked monkshood, 15-25 parts of cinnamon, 5-15 parts of cassia twig, 10-20 parts of morinda officinalis, 10-20 parts of angelica sinensis, 15-25 parts of caulis spatholobi, 15-25 parts of spina date seeds, 10-20 parts of schizonepeta, 10-20 parts of radix angelicae pubescentis, 10-20 parts of notopterygium roots, 10-20 parts of folium artemisiae argyi, 10-20 parts of ramulus mori, 10-20 parts of parasitic loranthus, 15-25 parts of radix puerariae, 5-15 parts of frankincense and 10-20 parts of myrrh.
Further, the traditional Chinese medicine composition comprises, by weight, 13-18 parts of raw astragalus membranaceus, 7-12 parts of cooked monkshood, 12-23 parts of cinnamon, 7-12 parts of cassia twig, 12-17 parts of morinda officinalis, 12-18 parts of angelica sinensis, 17-23 parts of caulis spatholobi, 17-22 parts of spina date seed, 12-18 parts of schizonepeta, 12-18 parts of radix angelicae pubescentis, 12-18 parts of notopterygium root, 12-18 parts of folium artemisiae argyi, 12-18 parts of ramulus mori, 12-18 parts of loranthus parasiticus, 17-23 parts of radix puerariae, 7-12 parts of frankincense and 13-18 parts of.
Further, the traditional Chinese medicine composition comprises, by weight, 15 parts of raw astragalus membranaceus, 10 parts of cooked monkshood, 20 parts of cinnamon, 10 parts of cassia twig, 15 parts of morinda officinalis, 15 parts of angelica sinensis, 20 parts of caulis spatholobi, 20 parts of spina date seed, 15 parts of schizonepeta, 5 parts of radix angelicae pubescentis, 15 parts of notopterygium root, 15 parts of folium artemisiae argyi, 15 parts of ramulus mori, 15 parts of parasitic loranthus, 20 parts of radix puerariae, 10 parts of frankincense and 15 parts of myrrh.
Further, the traditional Chinese medicine composition comprises, by weight, 18 parts of raw astragalus membranaceus, 12 parts of cooked monkshood, 20 parts of cinnamon, 12 parts of cassia twig, 17 parts of morinda officinalis, 18 parts of angelica sinensis, 23 parts of caulis spatholobi, 22 parts of spina date seed, 18 parts of schizonepeta, 18 parts of radix angelicae pubescentis, 18 parts of notopterygium root, 18 parts of folium artemisiae argyi, 18 parts of ramulus mori, 18 parts of parasitic loranthus, 23 parts of radix puerariae, 12 parts of frankincense and 18 parts of myrrh.
1. Pharmacological action of the ingredients
Raw astragalus root: sweet and mild in taste, has the effects of invigorating qi, consolidating superficial resistance, promoting sore, promoting granulation and inducing diuresis, and is mainly used for treating symptoms such as qi and blood weakness, spontaneous perspiration, chronic diarrhea, rectocele, uterine prolapse, nephritis edema, albuminuria, diabetes, chronic ulcer and the like.
Cooked monkshood: pungent and sweet in flavor and strongly hot in nature. Is toxic. It enters heart, kidney and spleen meridians. Has the effects of restoring yang, rescuing from collapse, tonifying fire, supporting yang, and expelling wind, cold and dampness. Can be used for treating yang exhaustion, collapse, cold limbs, slight pulse, sexual impotence, cold womb, psychroalgia of heart and abdomen, vomiting and diarrhea due to deficiency-cold, edema due to yin-cold, affection of exogenous pathogenic factor due to yang deficiency, and arthralgia due to cold-dampness.
Cinnamon: pungent and sweet in flavor and warm in nature. It enters kidney, spleen, heart and liver meridians. Has the effects of tonifying fire, supporting yang, guiding fire to the origin, dispelling cold, relieving pain, and warming and dredging channels and collaterals. Can be used for treating sexual impotence, cold womb, cold pain of waist and knee, asthma due to kidney deficiency, floating of deficient yang, giddiness, conjunctival congestion, cold pain of heart and abdomen, vomiting and diarrhea due to deficiency cold, cold hernia, abdominal pain, dysmenorrhea, and amenorrhea.
Cassia twig: pungent and sweet in flavor and warm in nature. It enters lung, heart and bladder meridians. Has effects of inducing sweat, relieving exterior syndrome, dispelling cold, relieving pain, activating yang, and regulating qi-flowing. Can be used for treating common cold due to wind-cold, pain due to cold accumulation and blood stagnation, phlegm retention, water retention syndrome, and palpitation.
Morinda officinalis: sweet and pungent in flavor and slightly warm in nature. It enters kidney and liver meridians. Has the effects of tonifying kidney yang, strengthening tendons and bones, and dispelling wind-damp. Can be used for treating sexual impotence, spermatorrhea, infertility due to cold womb, menoxenia, cold pain of lower abdomen, rheumatic arthralgia, and flaccidity of tendons and bones.
Chinese angelica: sweet and pungent in flavor and warm in nature. It enters liver, heart and spleen meridians. Has the effects of enriching blood, promoting blood circulation, regulating menstruation, relieving pain, moistening intestines and relaxing bowels. Can be used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, rheumatalgia, traumatic injury, superficial infection, pyocutaneous disease, intestinal dryness, and constipation. The wine angelica sinensis can activate blood and promote menstruation. Can be used for treating amenorrhea, dysmenorrhea, rheumatalgia, and traumatic injury.
Caulis spatholobi: bitter, sweet and warm. It enters liver and kidney meridians. Has the effects of promoting blood circulation, replenishing blood, regulating menstruation, relieving pain, relaxing muscles and tendons, and activating collaterals. Can be used for treating menoxenia, dysmenorrhea, amenorrhea, rheumatalgia, numbness, paralysis, and sallow complexion due to blood deficiency.
Wild jujube seed: sweet and sour in flavor and neutral in nature. It enters liver, gallbladder and heart meridians. Has the effects of nourishing heart, tonifying liver, calming heart, tranquilizing mind, arresting sweating and promoting fluid production. Can be used for treating vexation, insomnia, palpitation, dreaminess, asthenia, hyperhidrosis, body fluid deficiency, and thirst.
Herba schizonepetae: pungent in flavor and slightly warm in nature. It enters lung and liver meridians. Has the effects of relieving exterior syndrome, dispelling wind, promoting eruption and eliminating sore. Can be used for treating common cold, headache, measles, rubella, and initial stage of pyocutaneous disease.
Radix angelicae pubescentis: pungent and bitter with slightly warm nature. It enters kidney and bladder meridians. Has the effects of dispelling wind and removing dampness, and relieving pain and pain of arthralgia. Can be used for treating arthralgia due to wind-cold-dampness, lumbago, gonalgia, headache due to wind-cold-yin deficiency, and headache due to wind-cold-dampness.
Notopterygium root: pungent and bitter with warm nature. Enter bladder and kidney meridians. Has the effects of relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, eliminating dampness, and relieving pain. Wind-cold type common cold, wind-cold-dampness arthralgia, stiff neck, spasm of tendons and tendons, soreness and pain of joints, edema due to wind-damp, superficial infection and sore-toxin.
Folium artemisiae argyi: pungent, bitter and warm. It enters liver, spleen and kidney meridians. Channel warming, bleeding stopping, cold dispelling and pain relieving; it has the effects of dispelling dampness and relieving itching. Can be used for treating hematemesis, epistaxis, metrorrhagia, menorrhagia, fetal leakage, lower blood, lower abdomen psychroalgia, menoxenia, and infertility due to cold womb; it can be used for treating skin pruritus. Vinegar moxa charcoal can warm meridians and stop bleeding, and is indicated for bleeding due to deficiency-cold.
Mulberry twig: slightly bitter taste and mild nature. The liver meridian. Has the functions of expelling wind-damp and benefiting joints. Can be used for treating rheumatism, shoulder pain, arm pain, and arthralgia.
Parasitic loranthus: bitter and sweet in taste and neutral in nature. The liver and kidney meridians. Has effects in dispelling pathogenic wind and dampness, nourishing liver and kidney, strengthening tendons and bones, and protecting fetus. Can be used for treating rheumatalgia, soreness of waist and knees, weakness of bones and muscles, metrorrhagia, metrostaxis, pregnant hemorrhage, threatened abortion, and dizziness.
Kudzu root: sweet and pungent in flavor and cool in nature. It enters lung and stomach meridians. Has the effects of expelling pathogenic factors from muscles, relieving fever, promoting eruption, promoting salivation, quenching thirst, invigorating yang, and relieving diarrhea. Can be used for treating fever due to exterior syndrome, pain of neck and back, measles without adequate eruption, thirst due to fever, diabetes due to yin deficiency, dysentery due to heat-purging, and diarrhea due to spleen deficiency.
Frankincense: pungent, bitter and warm. It enters heart, liver and spleen meridians. Has the effects of promoting blood circulation, promoting qi circulation, relieving pain, eliminating swelling and promoting granulation. Can be used for treating thoracic obstruction, cardialgia, epigastralgia, dysmenorrhea, amenorrhea, puerperal blood stasis, abdominal pain, rheumatic arthralgia, spasm of muscles and tendons, traumatic injury, carbuncle, swelling, and pyocutaneous disease.
Myrrh: pungent and bitter in flavor and mild in nature. It enters heart, liver and spleen meridians. Has the effects of removing blood stasis, relieving pain, eliminating swelling and promoting granulation. Can be used for treating thoracic obstruction, cardialgia, gastralgia, dysmenorrhea, amenorrhea, puerperal blood stasis, abdominal mass, rheumatic arthralgia, traumatic injury, carbuncle, swelling, and pyocutaneous disease.
2. Theory of traditional Chinese medicine
The invention is inspired by the classic clinical treatment thought of the traditional Chinese medicine under the guidance of the theory of the traditional Chinese medicine, and is obtained through a large number of preparation process tests and years of practice. The Huangdi's classic on the internal classic of medicine records that the meridian is the main term, so the meridian goes through the blood and qi to nourish yin and yang, moisten the muscles and bones and benefit the joints. "Qing Dynasty leaf Tianshi" clinical evidence guideline medical record, delivery gate, pressing language "has: the governor vessel is the disease, and the antler is used for warming. "
In addition, TCM believes that governor vessel governs yang of the whole body, and governs all yang channels, which is the sea of yang vessels. That is, the governor vessel governs yang qi of the whole body, and the governor vessel is empty and deficient, which can cause symptoms such as soreness and weakness of the waist and back. The traditional Chinese medicine composition has the advantages that the traditional Chinese medicine composition has poor treatment effects by singly using qi-tonifying and blood-nourishing, blood circulation-activating and blood stasis-removing, cold evil invasion as a target and has poor treatment effects by warming up the governor vessel, tonifying qi and blood, dispelling cold and dredging collaterals, so that various symptoms are gradually relieved, the traditional Chinese medicine composition is in the uterus, passes through the brain, is in contact with the kidney, governs yang channels, regulates qi of the whole body, and is capable of warming up yang, strengthening the exterior of muscles, filling vital qi, transporting yang, enabling blood to pass through, strengthening kidney meridian, making the kidney difficult to attack, and wind-damp stasis toxin is easy to expel.
3. The pharmacological effects of the technical scheme of the invention are as follows:
the inventor creatively discovers that the pathogenesis of postpartum body pain is mostly deficiency of qi and blood, deficiency of yang and qi, and repeated affection of pathogenic wind and cold, so the treatment principle is to strengthen the body resistance and eliminate pathogenic factors, and both attack and tonification are applied; for treatment, it is advisable to warm yang qi, nourish yin and blood, expel wind and remove cold; therefore, the raw astragalus root for tonifying qi and the prepared aconite root for warming and tonifying yang qi are mainly used as monarch drugs in the technical scheme of the invention; cinnamon and cassia twig are used as ministers to warm and dredge channels and collaterals, morinda officinalis tonifies kidney yin and kidney yang, and angelica, caulis spatholobi and spina date seed are used for nourishing blood and tonifying yin; herba schizonepetae, notopterygium root and radix angelicae pubescentis are used as adjuvant drugs and also as guiding drugs, ramulus mori is good at dredging the qi of upper limbs, loranthus parasiticus is good at dredging the obstruction of muscles and joints, frankincense and myrrh are used for removing blood stasis and relieving pain, radix puerariae is used for treating all kinds of arthralgia, and plays a role in activating yin qi, folium artemisiae argyi is used for warming the channels and dredging collaterals, and also can be used for enlivening the spleen and walking on the surface of the whole. The traditional Chinese medicine composition is combined to play the functions of warming and activating yang, nourishing yin and blood, dispelling wind and removing cold, and is suitable for symptoms such as postpartum headache, aching muscles of trunk and limbs and the like.
A preparation prepared from a traditional Chinese medicine composition for treating postpartum body pain comprises the traditional Chinese medicine composition and pharmaceutically acceptable auxiliary materials.
The preparation is in the form of decoction, powder, paste, granules, pills, tablets or capsules; preferably a decoction.
A preparation method of a traditional Chinese medicine decoction for treating postpartum body pain comprises the following steps: weighing the components according to the proportion, cleaning, crushing, adding into 3-5L of water, and soaking for 10-30 minutes; decocting with slow fire after boiling, filtering, and cooling to obtain Chinese medicinal decoction.
Further, boiling with strong fire for 10-20 min, decocting with slow fire for 20 min, and naturally cooling to 55-60 deg.C.
A method for using Chinese medicinal decoction comprises selecting rectangular region from lumbar vertebra to back Shu line, 10cm on both sides of the posterior midline as fumigation part, and bathing and fumigating for 1 time per day with Chinese medicinal decoction. The inventor finds that the patient with simple deficiency syndrome or excess syndrome is few, and the postpartum qi and blood yin and yang deficiency and exogenous pathogenic factor invasion are most of the patients with deficiency and exogenous pathogenic factors, and the syndrome belongs to deficiency and exogenous infection, and the deficiency and the excess are the most of the patients, so the traditional Chinese medicine decoction is applied to the governor vessel fumigation and washing method to treat the postpartum bodily pain, the traditional Chinese medicine governor vessel fumigation and washing can stimulate skin sensory organs through the thermal property and infrared radiation, and the biochemical metabolism and the nervous system function of tissue cells are regulated through nerve conduction, thereby achieving the purpose of treating the disease and obtaining the satisfactory clinical curative effect.
The traditional Chinese medicine decoction disclosed by the invention is matched with the governor vessel fumigation treatment to fully utilize the advantages of the traditional Chinese medicine, can effectively solve the problems of postpartum general pain and the like, and is beneficial to promoting postpartum recovery, improving adverse psychological states and improving the receptivity of puerperae.
The traditional Chinese medicine composition is applied to preparing medicines for treating postpartum body pain, postpartum joint pain, postpartum arthralgia syndrome, postpartum headache or postpartum cold.
Example 1
A traditional Chinese medicine composition for treating postpartum body pain comprises: 10g of raw astragalus membranaceus, 5g of cooked monkshood, 15g of cinnamon, 5g of cassia twig, 10g of morinda officinalis, 10g of angelica, 15g of caulis spatholobi, 15-25g of spina date seed, 10g of schizonepeta, 10g of radix angelicae pubescentis, 10g of notopterygium root, 10g of folium artemisiae argyi, 10g of ramulus mori, 10g of parasitic loranthus, 15g of radix puerariae, 5g of frankincense and 10g of myrrh.
Example 2
A traditional Chinese medicine composition for treating postpartum body pain comprises: 20g of raw astragalus membranaceus, 15g of cooked monkshood, 25g of cinnamon, 15g of cassia twig, 20g of morinda officinalis, 20g of angelica, 25g of suberect spatholobus stem, 25g of spina date seed, 20g of schizonepeta, 20g of radix angelicae pubescentis, 20g of notopterygium root, 20g of folium artemisiae argyi, 20g of ramulus mori, 20g of parasitic loranthus, 25g of radix puerariae, 15g of frankincense and 20g of myrrh.
Example 3
A traditional Chinese medicine composition for treating postpartum body pain comprises: 15g of raw astragalus, 10g of cooked monkshood, 20g of cinnamon, 10g of cassia twig, 15g of morinda officinalis, 15g of angelica, 20g of suberect spatholobus stem, 20g of spina date seed, 15g of schizonepeta, 15g of radix angelicae pubescentis, 15g of notopterygium root, 15g of folium artemisiae argyi, 15g of ramulus mori, 15g of parasitic loranthus, 20g of radix puerariae, 10g of frankincense and 15g of myrrh.
Example 4
A traditional Chinese medicine composition for treating postpartum body pain comprises: 18g of raw astragalus membranaceus, 12g of cooked monkshood, 20g of cinnamon, 12g of cassia twig, 17g of morinda officinalis, 18g of angelica, 23g of suberect spatholobus stem, 22g of spina date seed, 18g of schizonepeta, 18g of radix angelicae pubescentis, 18g of notopterygium root, 18g of folium artemisiae argyi, 18g of ramulus mori, 18g of parasitic loranthus, 23g of radix puerariae, 12g of frankincense and 18g of myrrh.
Example 5
A traditional Chinese medicine composition for treating postpartum body pain comprises: 18g of raw astragalus membranaceus, 9g of cooked monkshood, 17g of cinnamon, 11g of cassia twig, 12g of morinda officinalis, 12g of angelica, 19g of suberect spatholobus stem, 19g of spina date seed, 13g of schizonepeta, 18g of radix angelicae pubescentis, 17g of notopterygium root, 18g of folium artemisiae argyi, 13g of ramulus mori, 13g of parasitic loranthus, 21g of radix puerariae, 8g of frankincense and 18g of myrrh.
Example 6
A traditional Chinese medicine composition for treating postpartum body pain comprises: 16g of raw astragalus membranaceus, 11g of cooked monkshood, 16g of cinnamon, 12g of cassia twig, 14g of morinda officinalis, 114g of angelica, 19g of suberect spatholobus stem, 19g of spina date seed, 16g of schizonepeta, 16g of radix angelicae pubescentis, 16g of notopterygium root, 13g of folium artemisiae argyi, 13g of ramulus mori, 13g of parasitic loranthus, 18g of radix puerariae, 12g of frankincense and 14g of myrrh.
Example 7
A traditional Chinese medicine composition for treating postpartum body pain comprises: 12g of raw astragalus membranaceus, 8g of cooked monkshood, 22g of cinnamon, 12g of cassia twig, 16g of morinda officinalis, 12g of angelica, 21g of suberect spatholobus stem, 19g of spina date seed, 17g of schizonepeta, 16g of radix angelicae pubescentis, 17g of notopterygium root, 16g of folium artemisiae argyi, 17g of ramulus mori, 16g of parasitic loranthus, 22g of radix puerariae, 7g of frankincense and 16g of myrrh.
Example 8
A traditional Chinese medicine composition for treating postpartum body pain comprises: 12g of raw astragalus, 11g of cooked monkshood, 19g of cinnamon, 12g of cassia twig, 11g of morinda officinalis, 12g of angelica, 23g of suberect spatholobus stem, 21g of spina date seed, 18g of schizonepeta, 12g of radix angelicae pubescentis, 18g of notopterygium root, 12g of folium artemisiae argyi, 18g of ramulus mori, 12g of parasitic loranthus, 21g of radix puerariae, 7g of frankincense and 12g of myrrh.
Example 9
Based on example 1, the following method was used to prepare a traditional Chinese medicine decoction: cleaning the components in the embodiment 1, removing surface impurities, pulverizing into powder, and soaking in 3L of water for 10 min; boiling with strong fire for 10 min, decocting with slow fire for 20 min, and naturally cooling to 55 deg.C to obtain Chinese medicinal decoction.
Example 10
Based on example 2, the following method was used to prepare a traditional Chinese medicine decoction: cleaning the components in the embodiment 2, removing surface impurities, grinding into powder, and adding the powder into 5L of water for soaking for 30 minutes; boiling with strong fire for 20 min, decocting with slow fire for 20 min, and naturally cooling to 60 deg.C to obtain Chinese medicinal decoction.
Example 11
Based on example 3, a traditional Chinese medicine decoction is prepared by the following method: cleaning the components in the embodiment 3, removing surface impurities, pulverizing into powder, and soaking in 4L of water for 20 minutes; boiling for 15 min, decocting with slow fire for 20 min, and naturally cooling to 55 deg.C to obtain Chinese medicinal decoction.
Example 12
Based on example 11, a method for using a Chinese medicinal decoction comprises the following steps: selecting the rectangular areas from the lumbar region of the back of the patient to the lumbar region of the back of the patient, wherein the rectangular areas are 10cm away from the middle line of the back of the patient, and bathing and fumigating the patients 1 time per day by using the Chinese medicinal decoction of example 11.
Examples of the experiments
(1) Subject: 75 postpartum body pain patients admitted by the hospital during the period from 5 months to 12 months in 2019 are selected to be included in the study, and are divided into 2 groups according to a random digital table method:
control group: 37 cases with age of 20-41 years, mean age (30.49 + -5.18 years), gestational weeks of childbirth of 37-42 weeks, gestational weeks of mean childbirth of 40.48 + -0.75 weeks, 31 cases of primiparous women, and 6 cases of menstruation-lying women;
study group: 38 cases, age 21-41 years, mean age (30.63 + -4.79 years), gestational weeks of childbirth 37-42 weeks, gestational weeks of mean childbirth (40.54 + -0.69) weeks, 33 cases of primiparous women, and 5 cases of puerpera women.
The data in 2 groups are compared, and the difference is not statistically significant (P is more than 0.05). The ethical committee of the hospital has been reported and approved.
(2) Inclusion criteria were: meeting the diagnosis standard of postpartum body pain; ② all the births are single births, delivery in term; ③ no diseases during gestation period; the patient knows the study and signs the consent.
Exclusion criteria: the medicine has acute infectious diseases, rheumatism, osteoarthritis and the like; ② the research relates to the allergic condition of the medicine; (iii) asthma; fourthly, the skin has a wound with an enlarged area; fifth, the patient has a history of high or low blood pressure or cardiac dysfunction.
(3) The application and observation method comprises the following steps: (2 treatment courses were all 4w)
Control group: massaging acupuncture points, and specifically implementing: the ward is provided with a special massage room and a special massage bed. Secondly, selecting acupuncture points: selecting shenting acupoint, yin tang acupoint, baihui acupoint, taiyang acupoint and fengchi acupoint on the head and face; the trunk is selected from Shenmen acupoint, Zusanli acupoint, Sanyinjiao acupoint, Xinshu, Pishu, Shenshu, Sanyinjiao, Yongquan acupoint, Taixi acupoint, etc. And thirdly, starting point massage at 24 hours after delivery to assist the lying-in woman to lie on the back/face on the massage bed, and smearing a proper amount of massage essential oil on the points for 45 min/time and 1 time/d before massage.
Study group: the traditional Chinese medicine governor vessel fumigation is combined with acupoint massage, the acupoint massage is the same as that of a control group, and the traditional Chinese medicine governor vessel fumigation is specifically implemented: the use method of the traditional Chinese medicine decoction of the embodiment 12 of the invention is adopted; secondly, connecting a water inlet pipe and a tap water faucet of a fumigation bed (model number: LXZ-200E, manufacturer: Hangzhou State Xin medical apparatus Co., Ltd.); thirdly, adding the prepared and decocted traditional Chinese medicine liquid into a fumigation container; fourthly, opening the tap water faucet and switching on the power switch; pressing the 'on/off' key once, lighting a fumigation indicator lamp, starting 'medicine fumigation' 2 grades for fumigation preheating in the operation, and switching back to 'medicine fumigation' 1 grade after preheating is finished; sixthly, assisting the patient to lie on the fumigation bed, fully exposing the back, ensuring that the governor vessel corresponds to the central depression of the fumigation bed, fumigating the governor vessel by traditional Chinese medicine steam generated after boiling the traditional Chinese medicine liquid in the fumigation container, adjusting the treatment time and temperature of the fumigation bed through a plus key and a minus key, wherein the treatment temperature is 38-42 ℃, and the treatment time is set to be 60 min; seventhly, when the set treatment time is up, the treatment is finished, the fumigation bed automatically returns to the standby state, the on/off key is pressed once, the fumigation indicator lamp is turned on and off, and the liquid in the fumigation container needs to be drained when the instrument is not used for a long time. The fumigating bed is provided with an ozone disinfection function, is opened by pressing a disinfection key for the first time and is closed by pressing the disinfection key again, and needs to be disinfected by ozone in an unmanned state.
(4) Standard of care
(4.1) Visual Analog Scale (VAS) score comparison. VAS evaluation was performed 1 time before and after treatment, with a VAS score ranging from 0 (no pain) to 10 (severe pain), and pain was evident in patients with high scores.
(4.2) serum pain mediator Substance P (Presence P, SP) levels were compared to 5-hydroxytryptamine (5-hydroxytryptamine, 5-HT). Before and after treatment, 5mL of maternal peripheral blood samples are collected once, centrifuged, and the serum SP and 5-HT levels are measured by ELISA.
(4.3) comparison of hemodynamics. 4 hemodynamic indexes including Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), Heart Rate (Heart Rate, HR) and Mean Arterial Pressure (MAP) were selected and measured 1 time before and after treatment.
And (4.4) comparing the uterine height, the abdominal circumference and the body mass index. Before and after treatment, uterine height, abdominal circumference and body mass index need to be measured, and the body recovery condition of the patient is evaluated.
(5) Statistical treatment
The data obtained in the research are analyzed by adopting statistical software SPSS 22.0, the metering data conforming to normal distribution are expressed by means of average +/-standard deviation, the inter-group comparison adopts independent sample t test, and the intra-group comparison adopts paired sample t test; the counting data are expressed in percentage, and the comparison among groups is expressed in chi2The test shows that the test level alpha is 0.05, and P < 0.05 shows that the difference is statistically significant.
(6) The experimental results are as follows:
(6.1) VAS score comparison
The VAS scores of the two groups before treatment are compared, the difference is not statistically significant (P is more than 0.05), the VAS scores of the two groups after treatment are lower than those before treatment (P is less than 0.05), and the VAS scores of the research group after treatment are lower than those of the control group (P is less than 0.05). See table 1.
TABLE 1VAS score comparison
| Group of | Number of examples | Before treatment | After treatment | t | P |
| Control group | 37 | 5.52±1.47 | 2.14±0.68 | 12.694 | 0.000 |
| Research group | 38 | 5.34±1.39 | 1.05±0.32 | 18.540 | 0.000 |
| t | - | 0.545 | 8.920 | - | - |
| P | - | 0.587 | 0.000 | - | - |
(6.2) comparison of serum pain mediator SP with 5-HT levels
The differences between serum SP and 5-HT levels in the pre-treatment group were not statistically significant (P > 0.05), the serum SP and 5-HT levels in both the post-treatment groups were decreased (P < 0.05), and the serum SP and 5-HT levels in the post-treatment study groups were lower than in the control group (P < 0.05). See table 2.
TABLE 2 comparison of serum pain mediator SP with 5-HT levels
Note: compared with the same group before treatment, P is less than 0.05.
(6.3) comparison of hemodynamics
Compared with SBP, DBP, HR and MAP in the two groups before treatment, the difference has no statistical significance (P is more than 0.05), SBP, DBP, HR and MAP in the two groups after treatment are all reduced (P is less than 0.05), and SBP, DBP, HR and MAP in the research group after treatment are all lower than that in the control group (P is less than 0.05). See table 3.
TABLE 3 hemodynamic comparison
TABLE 3
Note: compared with the same group before treatment, P is less than 0.05.
(6.4) comparison of uterine height, abdominal circumference and body constitution index
Compared with the uterine height, abdominal circumference and body mass index of the two groups before treatment, the difference has no statistical significance (P is more than 0.05), the uterine height, abdominal circumference and body mass index of the study group after treatment are all reduced (P is less than 0.05), and the uterine height, abdominal circumference and body mass index of the study group after treatment are all lower than those of the control group (P is less than 0.05). See table 4.
TABLE 4 comparison of uterine height, abdominal circumference and body constitution index
Note: compared with the same group before treatment, P is less than 0.05.
(1) As can be seen from the results in tables 1-2, there was essentially no significant difference between the VAS scores and the serum SP and 5-HT levels in the control and study groups prior to treatment. And the VAS score of the study group is lower than that of the control group after hospitalization; serum SP and 5-HT levels in the study group were lower than those in the control group after treatment; therefore, the decoction prepared by the traditional Chinese medicine composition provided by the invention is combined with the application method of traditional Chinese medicine governor vessel fumigation combined acupoint massage, so that the pain of a patient can be remarkably relieved, serum pain medium can be adjusted, and the analgesic effect is superior to that of single acupoint massage. Research shows that the generation and the degree of the pain are closely related to abnormal secretion of pain mediators (SP, 5-HT and the like are common), particularly SP and 5-HT can accurately transmit pain signals from the periphery to the central nervous system, and therefore pain generation is promoted. The acupoint massage can play a role in calming and inhibiting the nervous system, reduce the stress degree and reduce the release of pain substances. The traditional Chinese medicine governor vessel fumigation is carried out, under the combined action of potency of medicine, heat and the like, pores of the skin of the whole body are opened, the local blood circulation and the metabolism are obviously enhanced, an internal environment is provided for effectively removing substances causing pain, metabolic waste and the like, and the effect of relieving pain is achieved.
(2) The results in tables 3-4 show that there is no significant difference between the control group and the study group in 4 hemodynamic indexes including SBP, DBP, HR and MAP before treatment, uterine height, abdominal circumference and body mass index. SBP, DBP, HR, MAP were all lower in the study group than in the control group after admission. Therefore, the decoction prepared from the traditional Chinese medicine composition provided by the invention is combined with the application method of traditional Chinese medicine governor vessel fumigation combined acupoint massage, and based on the theory of channels, collaterals and acupoints, the decoction can act on specific acupoints to dredge the channels and activate collaterals, regulate qi and blood, and is beneficial to improvement of hemodynamics. The Chinese medicinal governor vessel fumigation can generate warm effect, under the combined action of medicinal potency, heat power, etc., the capillary vessel of fumigation part is in an expanded state, the blood circulation is accelerated, and medicinal potency can better penetrate skin and enter into striae, nourish viscera and channels and collaterals of the whole body, so that various indexes of hemodynamics can be improved.
Typical case data:
1. thank you, woman, admission number: 322 x, the patient had a temporary birth and a live baby due to premature rupture of fetal membranes, gestational diabetes, umbilical cord winding, G2P139+3 week pregnancy and live intra-uterine LOA. On the 2 nd day after delivery, the lower abdomen pain is obvious, the vagina bleeds a little, and the diagnosis of traditional Chinese medicine consultation is as follows: stagnation after delivery. According to the traditional Chinese medicine decoction and the using method thereof provided by the embodiment, the traditional Chinese medicine collapse and the traditional Chinese medicine steam bath are given once a day for 30 minutes each time. After 3 days of continuous treatment, the lower abdomen pain is obviously relieved, the vaginal bleeding is reduced, and after one week, the lower abdomen pain is basically free, and the vaginal bleeding phenomenon is avoided.
2. Cornuta, female, hospitalization number: 322 x, the patient is ready to give birth to a live baby due to premature rupture of the fetal membranes, G3P1+138+2 weeks of pregnancy and intra-uterine live ROA. On the 2 nd day after delivery, lower abdomen pain, bilateral hip pain and vaginal bleeding are obvious, and the diagnosis by traditional Chinese medicine consultation is as follows: qi stagnation and blood stasis. According to the traditional Chinese medicine decoction and the using method thereof provided by the embodiment, the traditional Chinese medicine collapse and the traditional Chinese medicine steam bath are given once a day for 30 minutes each time. After 3 days of continuous treatment, the lower abdomen pain and bilateral hip pain are obviously relieved, vaginal bleeding is reduced, and after one week, the lower abdomen pain and bilateral hip pain basically have no pain and vaginal bleeding phenomenon.
3. Sunny, female, hospital number: 322 x, patient had a viable infant due to intrauterine live LOA for G5P2+239+1 week. On the 2 nd day after delivery, the lower abdomen pain is obvious, the general muscle ache is obvious, the vaginal bleeding is a little, and the diagnosis by the traditional Chinese medicine consultation is as follows: qi stagnation and blood stasis. According to the traditional Chinese medicine decoction and the using method thereof provided by the embodiment, the collapse treatment of the traditional Chinese medicine is given once a day for 30 minutes each time. After 3 days of continuous treatment, the lower abdomen pain and the general aching pain are obviously relieved, the vaginal bleeding is reduced, the lower abdomen pain and the general pain do not exist basically after one week, and the vaginal bleeding does not exist.
In conclusion, the decoction prepared from the traditional Chinese medicine composition has remarkable promoting effects on eliminating pain symptoms, improving hemodynamics, reducing serum pain medium level, promoting body recovery and the like. The traditional Chinese medicine fumigation composition has the advantages that on the basis of highlighting the diagnosis and treatment concept of the traditional Chinese medicine theory and fully exerting the diagnosis and treatment advantages of the traditional Chinese medicine, the traditional Chinese medicine fumigation composition and the fumigation technology have a synergistic effect, and the positive effect is shown in the aspect of improving the curative effect of postpartum body pain.
Claims (10)
1. A traditional Chinese medicine composition for treating postpartum pain of body is characterized by comprising, by weight, 10-20 parts of raw astragalus membranaceus, 5-15 parts of cooked monkshood, 15-25 parts of cinnamon, 5-15 parts of cassia twig, 10-20 parts of morinda officinalis, 10-20 parts of angelica sinensis, 15-25 parts of caulis spatholobi, 15-25 parts of spina date seeds, 10-20 parts of schizonepeta, 10-20 parts of radix angelicae pubescentis, 10-20 parts of notopterygium roots, 10-20 parts of folium artemisiae argyi, 10-20 parts of ramulus mori, 10-20 parts of parasitic loranthus, 15-25 parts of radix puerariae, 5-15 parts of frankincense and 10-20 parts of myrrh.
2. The traditional Chinese medicine composition for treating postpartum pain of body as claimed in claim 1, wherein the composition comprises, by weight, 13-18 parts of raw astragalus membranaceus, 7-12 parts of prepared monkshood, 12-23 parts of cinnamon, 7-12 parts of cassia twig, 12-17 parts of morinda officinalis, 12-18 parts of angelica sinensis, 17-23 parts of caulis spatholobi, 17-22 parts of spina date seed, 12-18 parts of schizonepeta, 12-18 parts of radix angelicae pubescentis, 12-18 parts of notopterygium root, 12-18 parts of folium artemisiae argyi, 12-18 parts of ramulus mori, 12-18 parts of parasitic loranthus, 17-23 parts of radix puerariae, 7-12 parts of frankincense and 13-18 parts of myrrh.
3. The traditional Chinese medicine composition for treating postpartum pain of body as claimed in claim 1, wherein the composition comprises, by weight, 15 parts of raw astragalus membranaceus, 10 parts of cooked monkshood, 20 parts of cinnamon, 10 parts of cassia twig, 15 parts of morinda officinalis, 15 parts of angelica sinensis, 20 parts of caulis spatholobi, 20 parts of spina date seed, 15 parts of schizonepeta, 15 parts of radix angelicae pubescentis, 15 parts of notopterygium root, 15 parts of folium artemisiae argyi, 15 parts of ramulus mori, 15 parts of loranthus parasiticus, 20 parts of radix puerariae, 10 parts of frankincense and 15 parts of myrrh.
4. The traditional Chinese medicine composition for treating postpartum pain of body as claimed in claim 1, wherein the composition comprises, by weight, 18 parts of raw astragalus membranaceus, 12 parts of cooked monkshood, 20 parts of cinnamon, 12 parts of cassia twig, 17 parts of morinda officinalis, 18 parts of angelica sinensis, 23 parts of caulis spatholobi, 22 parts of spina date seed, 18 parts of schizonepeta, 18 parts of radix angelicae pubescentis, 18 parts of notopterygium root, 18 parts of folium artemisiae argyi, 18 parts of ramulus mori, 18 parts of loranthus parasiticus, 23 parts of radix puerariae, 12 parts of frankincense and 18 parts of myrrh.
5. Use of a Chinese medicinal composition according to any one of claims 1 to 4 in the preparation of a medicament for the treatment of postpartum pain of the body, postpartum arthralgia, postpartum pain, postpartum headache or postpartum cold.
6. A Chinese medicinal preparation for treating postpartum pain of body, which is characterized by comprising the Chinese medicinal composition of any one of claims 1-4 and pharmaceutically acceptable auxiliary materials.
7. The traditional Chinese medicine preparation for treating postpartum body pain according to claim 6, wherein the preparation is in the form of any one of decoction, powder, paste, granules, pills, tablets or capsules.
8. The traditional Chinese medicine preparation for treating postpartum body pain according to claim 7, wherein the preparation is in the form of decoction.
9. The preparation method of the traditional Chinese medicine preparation for treating postpartum body pain according to claim 8, characterized by comprising the following steps: weighing the components according to the proportion, cleaning, crushing, and soaking in water for 10-30 minutes; decocting with slow fire after boiling, filtering, and cooling to obtain Chinese medicinal decoction.
10. The method for preparing a Chinese medicinal preparation for treating postpartum pain of body as claimed in claim 9, wherein the preparation is prepared by boiling with strong fire for 10-20 minutes, decocting with slow fire for 20 minutes, filtering, and naturally cooling to 55-60 deg.C to obtain a Chinese medicinal decoction.
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Application publication date: 20201204 |