CN104324108B - External-use traditional Chinese medicine composition for treating knee osteoarthritis (arthralgia syndrome) - Google Patents

External-use traditional Chinese medicine composition for treating knee osteoarthritis (arthralgia syndrome) Download PDF

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CN104324108B
CN104324108B CN201410491208.8A CN201410491208A CN104324108B CN 104324108 B CN104324108 B CN 104324108B CN 201410491208 A CN201410491208 A CN 201410491208A CN 104324108 B CN104324108 B CN 104324108B
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medicine composition
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熊桂华
矫俊东
高金良
杨冬雨
刘舒音
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Changchun University of Chinese Medicine
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Abstract

The invention relates to an external-use traditional Chinese medicine composition for treating knee osteoarthritis (arthralgia syndrome), the traditional Chinese medicine composition comprises the following raw materials of papaya, gardenia, rhubarb, dandelion, frankincense, myrrh, rhizoma corydalis, safflower, angelica, radix clematidis and rhizoma cibotii in the mass ratio of 4:3:3:4:2:2:6:2:3:4:6. The traditional Chinese medicine composition uses a monarch, minister, assistant and guide formula, and uses traditional Chinese acupoint therapy and modern medicine transdermal absorption theory, the external-use traditional Chinese medicine composition is crushed into powder, and mixed with yellow wine to prepare a paste, and the paste is applied to heding of two sides of human body and the acupuncture points of inner and outer eyes of the knee. By stimulation of acupuncture points, conduction of main and collateral channels, dredging of main and collateral channels, promoting of blood circulation, and removing of blood stasis, tendons and vessels and qi and blood are smoothened so as to achieve the purpose of treatment. The medicine administration method is convenient, the medicine effect is lasting, adverse reaction is less, the recovery and effecting rate is 18%, the effective rate is 72%, the total effective rate is 90%, and the external-use traditional Chinese medicine composition is an effective medicine for the treatment of the knee osteoarthritis.

Description

The external medicine composition for the treatment of knee joint osseous arthritis (damp arthralgia)
Technical field
The invention belongs to technical field of Chinese medicines, treat outside knee joint osseous arthritis (damp arthralgia) more particularly to one Use Chinese medicine composition.
Background technology
Knee joint osseous arthritis is a kind of chronic joint being characterized with degeneration, destruction and the hyperosteogeny of articular cartilage Disease, also known as Knee Arthritis, senile gonarthritis.It is a kind of chronic joint diseases, and its main change is that knee joint closes The degeneration of joint cartilage surface and insecondary hyperosteogeny.Main performance be arthralgia and activity dumb, x-ray performance is closed Joint gap turn narrow, subchondral bone matter is fine and close, and bone trabecula ruptures, and has hardening and cystis degeneration, and joint margins has lip sample hypertrophy, later stage bone End deformation, articular surface is uneven, and intraarticular cartilage peels off, and sclerotin fragmentation enters joint, forms articular mobile corpus.
Falling ill with person in middle and old age clinically most common, women is more than male.Pathological characteristic is the regression of focal articular cartilage Property become, subchondral bone qualitative change close (hardening), marginality bone cartilage hyperosteogeny formation and joint deformity.
Modern medicine is thought, knee joint osseous arthritis is divided into constitutional and Secondary cases two kinds.Constitutional person is owing to closing Joint cartilage degeneration and joint are caused by chronic injury, and fat and inherited genetic factors etc. also has a certain impact, multiple be born in old Year people.Secondary cases person is due to knee wound, strain, chronic inflammatory disease, and the inside and outside talipes varus of knee joint etc. is caused, such as condyle of femur or Fracture of the tibial plateau, Patella fracture or dislocation, articular cartilage damage, meniscus injury, Chondromalacia of patella etc., multiple be born in blue or green strong Year.
The traditional Chinese medical science is thought: liver governing tendons, kidney governing bones.The full then muscle strength of Liver and kidney is strong, the sliding profit in joint.In the middle age with year, Liver and kidney is gradually Virtual loss, deficiency of kidney-QI, muscles and bones loses it and supported, and muscle cartilage withers, or hold concurrently suffer wind-cold damp pathogen in invade, easily send out primary disease.If knee wound, labor Damaging, QI-blood circulation is not smooth, and passages through which vital energy circulates is obstructed, and causes muscles and bones to be lost and supports and fall ill.
Damp arthralgia, has another name called arthralgia chiefly caused by damp pathogen, is not enough by human righteousness, experiences damp, or folder wind, folder are trembled with fear, folder heat, attack skin, muscle Bone, joint, cause the resistance of QI and blood numbness and cause ache with limbs joint, weigh, swelling, the joint stuffiness one as principal character Disease.Primary disease is one of clinical Familiar Rheumatism, the most all can fall ill, be common with long summer, season in severe winter.Age of onset With person between twenty and fifty for many, sex difference is little.
The method for the treatment of knee joint osseous arthritis is varied at present, can be divided into non-operative treatment and operative therapy, and The former is the most the most frequently used, and patient is easily accepted by most, and non-operative treatment can be divided into physical therapy, laser irradiation, acupuncture therapy, auxiliary The modes such as assistant engineer's tool, injection treatment, medicine.The Treatment of Osteoarthritis of Knee Joint with External Therapy of Chinese Traditional Medicine often with invigorating the liver and kidney, bone and muscle strengthening, is dispelled Wind, dissipating cold, dehumidifying invigorates blood circulation, and removing obstruction in the collateral to relieve pain is method.The determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of the Treatment of Osteoarthritis of Knee Joint with External Therapy of Chinese Traditional Medicine and internal treatment Principle is identical, curative effect the most definite (list of references, sun rising sun liter, Jin Jiachang, Jin He Chinese medicine external treatment knee joint bone Arthritis progress, " traditional Chinese medical science bonesetting ", the 2nd phase of volume 22 in February, 2010).
Summary of the invention
In order to solve the problem that prior art exists, the Chinese medicine of abundant treatment knee joint osseous arthritis, meanwhile, also In order to clinical treatment primary disease is more targeted, the invention provides a kind of special for treating knee joint osseous arthritis (damp arthralgia) External medicine composition.Described external medicine composition selects acupoint application of Chinese herb, is conducted by meridians, QI and blood regulating, dispels Wind dehumidifies, and makes channels and collaterals dredging, muscle support, and bone has been given birth to, thus reaches the purpose of cure diseases.
The raw material composition of the external medicine composition of the treatment knee joint osseous arthritis (damp arthralgia) that the present invention provides and matter Amount proportioning is as follows: Fructus Chaenomelis: Fructus Gardeniae: Radix Et Rhizoma Rhei: Herba Taraxaci: Olibanum: Myrrha: Rhizoma Corydalis: Flos Carthami: Radix Angelicae Sinensis: Radix Clematidis: the quality of Rhizoma Cibotii Ratio is 4:3:3:4:2:2:6:2:3:4:6.
Fructus Chaenomelis, nature and flavor: put down, be slightly cold, sweet, return liver, spleen channel.Effect: suppressing the hyperactive liver, relaxing muscles and tendons, and spleen, removing dampness.Fructus Chaenomelis sarcocarp In the carpaine that contains there is the effect alleviating spasm pain, row's myenteron spasm is had obvious therapeutical effect.Fructus Chaenomelis taste Acid, slightly warm in nature, Main Function is damp eliminating numbness, relaxing muscles and tendons and activating QI and blood in the collateral, for rheumatalgia patient's optimum.Arrest for rheumatic arthralgia, muscle arteries and veins Contraction, tinea pedis swell and ache.Fructus Chaenomelis has preferable relaxing muscles and tendons and activating QI and blood in the collateral effect, and energy removing dampness, is commonly used by dispelling the wind and dampness pathogens arthralgia pain, and arteries and veins contracture person is outstanding for muscle For key medicine.As Fructus Chaenomelis is decocted, control muscular contracture stiffness of the nape, unable to move around, i.e. join Olibanum, Myrrha, the Radix Rehmanniae with this product.
Fructus Gardeniae, nature and flavor: bitter, cold, GUIXIN, liver, lung, stomach, tri-jiao channel.Function cures mainly: cooling blood for hemostasis, and Fructus Gardeniae has detumescence only Effect of pain, Compendium of Material Medica: " controlling ... traumatic blood stasis ... " modern study shows, its experiment to animal soft tissue damage There is preferable therapeutical effect.
Flos Carthami, nature and flavor: Xin Wen, GUIXIN, Liver Channel, effect: promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing, can be used for traumatic injury. " detailed outline ": invigorate blood circulation, moisturizes, pain relieving, dissipates swollen, stimulates the menstrual flow." medicineization justice ": Flos Carthami, kind tonneau passages through which vital energy circulates, for gas medicine in blood, can rush down and Can mend again, be respectively arranged with wonderful justice.Modern study shows that Carthamus yellow and yellow II, yellow III has and improves Peripheral Microcirculation obstructive action, makes Blood flow accelerates, the open number of capillary network increases and Blood cell accumulation degree alleviates.
Radix Angelicae Sinensis, nature and flavor: Gan Xinwen.Return liver, the heart, spleen channel.It is replenishing and activating blood, rheumatic arthralgia, injury from falling down that function cures mainly. " Treatise on Febrile Disease with Notes " is recorded: " promoting blood circulation ".Meanwhile, modern study record Radix Angelicae Sinensis decoct ear vascular perfusion stream can make a rabbit blood vessel relax , water extract-alcohol precipitation liquid intravenous can make anesthetized dog arterial pressure decline, arteria coronaria, cerebral arteries and femoral artery drop in resistance, and blood flow increases.
Herba Taraxaci, nature and flavor: bitter sweet cold.Gui Jing: enter liver, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, diuresis eliminating stagnation.Control acute breast Adenitis, lymphadenitis, scrofula, furuncle carbuncle toxin, " the southern regions of the Yunnan Province book on Chinese herbal medicine " is recorded: apply all pyogenic infections from tumour or sore, mange tinea skin ulcer;Dispeling the wind, disappear all sores, Dissipate scrofula tuberculosis." detailed outline " is recorded: strengthening bone and muscle.
Olibanum, nature and flavor: arduous temperature.Gui Jing: enter the heart, liver, spleen channel.Cure mainly: regulating qi and activating blood, analgesic therapy, chase after poison.Control QI and blood to coagulate Stagnant, ulcerative carbuncle toxic swelling." detailed outline ": Olibanum perfume (or spice) is altered, and enters heart channel, analgesic therapy of invigorating blood circulation, therefore be ulcer sores, cardiac and abdominal pain key medicine." Plain Questions " cloud: All sufferings skin infection, all belonging to heart-fire is.The all sides of obstetrics multiplex it, also take its merit invigorated blood circulation you.... Yang Qing old man's cloud: ordinary person's muscle is not The person of stretching, the drug of topical application preferably adds Olibanum, and its performance stretches muscle." Bencao Jingshu ": edema due to wind pathogen poison is swollen, invade in evil dry heart spleen, bad odor, also by two through void And heresy is easily violated.Urticaria itch poison, always because heart spleen is done cause by rheumatism pathogenic heat.Spleen governing muscles and sufferings skin infection all belongs to heart-fire, this medicine Just entering two warps, pungent perfume can dissipate all and stay knot, and the most all cards are from recover.
Myrrha: nature and flavor: toil is put down.Return liver, spleen, the heart, kidney channel.Function cures mainly: dissipate blood blood stasis removing, subduing swelling and relieving pain.Control and fall damage, Incised wound, muscles and bones, all pains of trusted subordinate, abdominal mass, amenorrhea, ulcer sore pain.Amplification on Canon of Materia Medica: Myrrha, general logical stagnant blood, beat and flutter damage pain, All take with alcoholizing.Stasis then gas is stopped up solidifying, and it is completely anxious that gas stops up solidifying then meridians, and meridians are completely anxious, therefore pain and swollen.All beating flutters muscle palpus swelling Person, meridian trauma, QI and blood is not all right, stops up solidifying, therefore in this way." Elementary Medicine ": east wall cloud, Chuan Sanxuezhi section controlled by Myrrha.This medicine pushes away old Cause new, therefore stagnated blood can be broken, reducing swelling and alleviating pain, for the strange medicine of persons particularly liable to develop skin infection also.Compendium of Material Medica: dissipate blood detumescence, analgesic therapy granulation promoting." book on Chinese herbal medicine guiding principle Mesh ": Olibanum is invigorated blood circulation, and Myrrha dissipates blood, all can alleviating pain and detumescence, granulation promoting, thus two medicines mutually hold concurrently and use.
Rhizoma Corydalis, warm in nature, acrid in the mouth is bitter, and GUIXIN, spleen, liver, lung, be the quality goods of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, especially with the merit of pain relieving Imitate and be world-famous for.Li Shizhen (1518-1593 A.D.) concludes Rhizoma Corydalis in Compendium of Material Medica " invigorate blood circulation, promoting the circulation of QI, pain relieving, diuresis " four large effects, and High praise Rhizoma Corydalis " stagnation of QI, stasis in gas in energy promoting the circulation of blood, therefore specially control upper and lower all pains all over the body ".
Radix Clematidis, nature and flavor: pungent, salty, temperature, poisonous.Return bladder warp.Expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, dissipate the hypochondriac lump.Main Control gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, knee joint cold type of pain, muscle arteries and veins contracture, joint stuffiness, tinea pedis, malaria, lump in the abdomen, broken wound Wind, tonsillitis, all a fishbone or other bone caught in the throat swallow." Kaibao Bencao ": main all wind, logical five Tibetan of a surname, cold stagnant in removing abdomen, septum cordis expectorant water amasss for a long time, lump in the abdomen Xuan tinea air parcel, bladder place pus aversion to water, the cold pain of waist knee joint and treatment injured." Guangxi Chinese herbal medicine ": expelling wind and removing dampness, dredge the meridian passage, diuresis, only Bitterly.Dispelling the wind and dampness pathogens osteodynia, jaundice, edema, dysuria, migraine, internal traumatic injury.
Rhizoma Cibotii, nature and flavor: bitter, sweet, warm;Return liver, kidney channel.Function cures mainly: invigorating the liver and kidney, wind-damp dispelling, strong waist foot, profit joint.Control Back ache, gonalgia flaccidity of the lower limbs, cold-damp general arthralgia, lose and drown, frequent micturition, seminal emission, leucorrhea." herbal classic ": main back is strong, office's emergency, general arthralgia Cold-damp, gonalgia.Quite profit old man." not Lu ": treat that losing drowns does not saves, man's flaccidity of the lower limbs lumbago, ailment said due to cold or exposure drenches dew, few gas mesh, and hard ridge, profit is bowed Face upward, woman's damaging the spleen and stomach, joint weight." property of medicine opinion ": controlling man's woman's poison wind weak foot, pathogen arthralgia chiefly caused by damp pathogen, kidney qi is weak, tonification man, stricture of vagina Muscles and bones." detailed outline ": strong Liver and kidney, strong bone, control wind empty.
Radix Et Rhizoma Rhei, nature and flavor: bitter, cold.Gui Jing: stomach warp;Large intestine channel;Liver Channel;Spleen channel effect: blood stasis dispelling.Cure mainly: traumatic injury.With In traumatic injury, the stasis of blood is stagnant has a pain.Shennong's Herbal records its main lower blood stasis, blood closes, cold and heat, broken lump in the abdomen." it is on the point of Hu Ji Letter side " record its " control and beat servant's scar, blood stasis rolling note, or the person that makees hectic fever: rhei,rhizoma pulveratum, Sucus Zingberis are adjusted and be coated with.At one night, black person is purple, two nights, Purple person is white also.”
Fructus Chaenomelis 4g, Fructus Gardeniae 3g, Radix Et Rhizoma Rhei 3g, Herba Taraxaci 4g, Olibanum 2g, Myrrha 2g, Rhizoma Corydalis 6g, Flos Carthami 2g, Radix Angelicae Sinensis 3g Wheeling Celestial 4g Rhizoma Cibotii 6g.
The present invention is with monarch prescription, with Rhizoma Corydalis, Rhizoma Cibotii as monarch drug.Rhizoma Corydalis, warm in nature, acrid in the mouth is bitter, GUIXIN, spleen, liver, Lung, can " invigorate blood circulation, promoting the circulation of QI, pain relieving, diuresis " " stagnation of QI, stasis in gas in energy promoting the circulation of blood, therefore specially control upper and lower all pains all over the body ";Canis familiaris L. Ridge, nature and flavor: bitter, sweet, warm;Return liver, kidney channel.Back ache, gonalgia flaccidity of the lower limbs, cold-damp general arthralgia can be treated.With two medicines as monarch, jointly send out Wave wind-damp dispelling, the effect in profit joint.
With Fructus Chaenomelis, Herba Taraxaci, Radix Clematidis as ministerial drug, Fructus Chaenomelis, returns liver, spleen channel.Can coordinate monarch drug to reach relaxing muscles and tendons, removing dampness.Main Acting on is damp eliminating numbness, relaxing muscles and tendons and activating QI and blood in the collateral, for rheumatalgia patient's optimum.Fructus Chaenomelis has preferable relaxing muscles and tendons and activating QI and blood in the collateral effect, and can change Wet, commonly used by dispelling the wind and dampness pathogens arthralgia pain, muscle arteries and veins contracture person particularly key medicine.
Herba Taraxaci returns liver, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, diuresis eliminating stagnation." the southern regions of the Yunnan Province book on Chinese herbal medicine " is recorded: apply all pyogenic infections from tumour or sore, Mange tinea skin ulcer;Dispeling the wind, disappear all sores, dissipates scrofula tuberculosis." detailed outline " is recorded: strengthening bone and muscle.Coordinate monarch drug can increase bone and muscle strengthening to dispel Effect of wind.
Radix Clematidis returns bladder warp.Expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, dissipate the hypochondriac lump.Cure mainly gout insensitive impediment, rheumatic arthralgia, Numb limbs and tense tendons, knee joint cold type of pain, muscle arteries and veins contracture, joint stuffiness." Guangxi Chinese herbal medicine ": expelling wind and removing dampness, dredge the meridian passage, diuresis, pain relieving.Control Rheumatic ostalgia.Thus strengthen effect of monarch drug expelling wind and removing dampness.、
With Fructus Gardeniae, Radix Et Rhizoma Rhei, when being classified as adjuvant drug, in primary disease pathogenic process, may occur in which the diseases such as swelling pain, and Fructus Gardeniae have Effect of reducing swelling and alleviating pain, Radix Et Rhizoma Rhei stasis-dispelling and pain-killing, Chinese angelica blood supplementing are invigorated blood circulation, wind-damp dispelling stopping numbness pain effect, and medicine-feeding combination can assist monarch drug Reach to enrich blood, blood stasis dispelling, dispel the wind, dehumidify, effect of pain relieving, therefore medicine can be promoted and absorb, strengthen each medicine in full side and jointly act on;
Olibanum, Myrrha, Flos Carthami for making medicine, three medicines make mutually with monarch drug into, play the function of blood-activating and qi-promoting altogether, Myrrha compatibility is red Budelium promoting blood circulation and stopping pain, Flos Carthami activating blood and removing stasis stimulates the menstrual flow.Three share, have invigorate blood circulation, silt of dispelling, stimulate the menstrual flow, effect of pain relieving, with monarch drug Coordinating, logical to reach blood then gas, blood then wind damp eliminating removes.
Described Chinese medicine composition reasonable recipe, full side plays blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, the merit of expelling wind and removing dampness altogether.
Using yellow wine as extra conductant ingredient, Compendium of Material Medica is said " all wine alcohol is different, and only rice wine enters medicinal " (rice wine i.e. yellow wine), Yellow wine can help blood circulation, enhances metabolism, and has blood-enriching face-nourishing, cold relieving of invigorating blood circulation, the effect of dredge the meridian passage.
Use Traditional Chinese Medicine acupoint therapy and modern pharmacy Transdermal absorption theoretical, use Chinese medicine composition acupoint application treatment Treatment knee joint osseous arthritis, is the characteristic of the present invention.
Research shows, persistently stimulates human acupoint, can make to be distributed in the subcutaneous nerve in corresponding acupuncture point and blood vessel is in one Excitatory state, the ability of mass exchange is strengthened, and promotes the nerve of human body, Humoral immunity effect and immunologic function, improves phase Close the functional activity of organ, thus reach to treat the purpose of disease.
Cave, Heding belongs to extra nerve points, i.e. points not mentioned in the ancient medical classics, is positioned at above-knee portion, goes down on one's knees, and recess above the midpoint at the bottom of kneecap, its subcutaneous shallow-layer has hidden Nervous ramification and rami cutanei anteriores nervi femoralis distribution;Deep layer has femoral nerve articular branches and the distribution of Knee joint artery net.Function cures mainly as logical Profit joint, expelling wind and removing dampness, activating collaterals to relieve pain.Inside and outside point ex-le 5, extra nerve points, i.e. points not mentioned in the ancient medical classics name, comes from Thousand Golden Prescriptions, calls knee joint mesh.Acupoint selection: Go down on one's knees, at patellar ligament both sides recess, at the title neix of inner side, the outer Xiyan of the title in outside, totally four cave, left and right, it is furnished with hidden god The infrapatellar branch of warp and shin, the most inside and outside articular branches of common peroneal nerve, the dynamic and static network of vein of knee joint.Cure mainly gonalgia, legs and feet weight pain, foot Gas, and knee joint and surrounding soft tissue thereof are scorching, crural paralysis etc..Three caves are knee joint near-end acupuncture point, but it is to knee joint disease Sick excellent treatment effect, therefore choose three cave associatings, it is coated with Chinese medicine, up to the purpose of disease recovery from illness.
The using method of the external medicine composition for the treatment of knee joint osseous arthritis (damp arthralgia) provided by the present invention is such as Under: described Chinese medicine composition is ground into powder, and the amount of every pair of medicine is as follows: Fructus Chaenomelis 4g, Fructus Gardeniae 3g, Radix Et Rhizoma Rhei 3g, Herba Taraxaci 4g, Olibanum 2g, Myrrha 2g, Rhizoma Corydalis 6g, Flos Carthami 2g, Radix Angelicae Sinensis 3g, Radix Clematidis 4g, Rhizoma Cibotii 6g.Add yellow wine and mix well into pasty state, even application On medically acceptable 3 or 6 pieces of strile gauze dressings, spread on human body one side or bilateral (may occur in which one side or bilateral knee joint Osteoarthritis) cave, Heding, inside and outside point ex-le 5, indwelling every day was taken off after 8-10 hour.The most concrete consumption is exactly every pair The amount of medicine.Within 10 days, it is a course for the treatment of, is spaced 2 two courses for the treatment of.
Taboo: this Chinese medicine composition skin allergy person is disabled.
Efficacy determination: comment with reference to State Administration of Traditional Chinese Medicine's " Chinese medical disease Standardization of diagnosis and curative effect " curative effect of formulating in 1994 Calibration standard.
Recovery from illness: transference cure, joint movement function recovers normal, and without arthroncus, stair activity is without pain, and local is without pressure Bitterly, joint motion is without bony crepitus, stiff without obvious morning;
Effective: symptom alleviates, joint movement function still can, joint not enlargement pain, stair activity is the most uncomfortable, joint live Without bony crepitus time dynamic, stiff without obvious morning, tibia medial epicondyle or the light tenderness of patella;
Effective: symptom alleviates, joint movement function takes a turn for the better earlier above, and local pain alleviates, and stair activity pain takes a turn for the better earlier above, Even during joint motion have bony crepitus, and morning, deadlock alleviated earlier above;
Invalid: symptom, sign are unchanged, joint movement function is without improvement, stair activity, arthroncus, locally tenderness, morning Deadlocks etc. are without changing.
Treatment case and therapeutic effect statistics:
According to above-mentioned evaluation criteria, use Drug therapy knee osteoarthritis patients 100 example of the present invention, wherein, Man's 31 examples, female 69 example;Age 20~70 years old, average 48.7 years old;The course of disease 5 days~20 years, average 10.8 months.
Administration time is 3-5 the course for the treatment of.
Recovery from illness and obvious effective rate 18.0%, 3 examples of fully recovering, effective 15 examples;Totally 18 people, male 6 examples, female 12 example;Age 20~42 years old, Average 31.8 years old;The course of disease 5 days~2 years, average 3.7 months.Slight 2 examples;Moderate 14 example;Severe 2 example.
Effective percentage is 72.0%;Totally 72 people, male 28 examples, female 44 example;Age 25~62 years old, average 42.0 years old;The course of disease 15 days~ 3 years, average 5.0 months.Slight 30 examples;Moderate 28 example;Severe 14 example.
Invalid is 10.0 %;Totally 10 people, male 6 examples, female 4 example;Age 55~70 years old, average 60.1 years old;The course of disease 3 months~ 10 years, average 5.4 years.Severe 10 example.
Beneficial effect: the external medicine composition of the treatment knee joint osseous arthritis (damp arthralgia) that the present invention provides, with monarch Minister assistant makes prescription, and the present invention is with monarch prescription, with Rhizoma Corydalis, Rhizoma Cibotii as monarch drug.Rhizoma Corydalis, warm in nature, acrid in the mouth is bitter, GUIXIN, spleen, Liver, lung, can " invigorate blood circulation, promoting the circulation of QI, pain relieving, diuresis " " stagnation of QI, stasis in gas in energy promoting the circulation of blood, therefore specially control upper and lower all pains all over the body "; Rhizoma Cibotii, nature and flavor: bitter, sweet, warm;Return liver, kidney channel.Back ache, gonalgia flaccidity of the lower limbs, cold-damp general arthralgia can be treated.With two medicines as monarch, jointly Play wind-damp dispelling, the effect in profit joint.
With Fructus Chaenomelis, Herba Taraxaci, Radix Clematidis as ministerial drug, Fructus Chaenomelis, returns liver, spleen channel.Can coordinate monarch drug to reach relaxing muscles and tendons, removing dampness.Main Acting on is damp eliminating eliminating impediment, relaxing muscles and tendons and activating QI and blood in the collateral, for rheumatalgia patient's optimum.Fructus Chaenomelis has preferable relaxing muscles and tendons and activating QI and blood in the collateral effect, and energy Removing dampness, is commonly used by dispelling the wind and dampness pathogens arthralgia pain, muscle arteries and veins contracture person particularly key medicine.
Herba Taraxaci returns liver, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, diuresis eliminating stagnation." the southern regions of the Yunnan Province book on Chinese herbal medicine " is recorded: apply all pyogenic infections from tumour or sore, Mange tinea skin ulcer;Dispeling the wind, disappear all sores, dissipates scrofula tuberculosis." detailed outline " is recorded: strengthening bone and muscle.Coordinate monarch drug can increase bone and muscle strengthening to dispel Effect of wind.
Radix Clematidis returns bladder warp.Expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, dissipate the hypochondriac lump.Cure mainly gout insensitive impediment, rheumatic arthralgia, Numb limbs and tense tendons, knee joint cold type of pain, muscle arteries and veins contracture, joint stuffiness." Guangxi Chinese herbal medicine ": expelling wind and removing dampness, dredge the meridian passage, diuresis, pain relieving.Control Rheumatic ostalgia.Thus strengthen effect of monarch drug expelling wind and removing dampness.、
With Fructus Gardeniae, Radix Et Rhizoma Rhei, when being classified as adjuvant drug, in primary disease pathogenic process, may occur in which the diseases such as swelling pain, and Fructus Gardeniae have Effect of reducing swelling and alleviating pain, Radix Et Rhizoma Rhei stasis-dispelling and pain-killing, Chinese angelica blood supplementing are invigorated blood circulation, wind-damp dispelling stopping numbness pain effect, and medicine-feeding combination can assist monarch drug Reach to enrich blood, blood stasis dispelling, dispel the wind, dehumidify, effect of pain relieving, therefore medicine can be promoted and absorb, strengthen each medicine in full side and jointly act on;
Olibanum, Myrrha, Flos Carthami for making medicine, three medicines make mutually with monarch drug into, play the function of blood-activating and qi-promoting altogether, Myrrha compatibility is red Budelium promoting blood circulation and stopping pain, Flos Carthami activating blood and removing stasis stimulates the menstrual flow.Three share, have invigorate blood circulation, silt of dispelling, stimulate the menstrual flow, effect of pain relieving, with monarch drug Coordinating, logical to reach blood then gas, blood then wind damp eliminating removes.
Described Chinese medicine composition reasonable recipe, full side plays blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, the merit of expelling wind and removing dampness altogether.
Described Chinese medicine composition reasonable recipe, full side plays product blood stasis dispelling of invigorating blood circulation, removing obstruction in the collateral to relieve pain, the merit of expelling wind and removing dampness altogether.
Using yellow wine as extra conductant ingredient, blood circulation promoting, accelerate metabolism, there is the work of cold relieving of invigorating blood circulation, dredge the meridian passage With.
Use Traditional Chinese Medicine acupoint therapy and modern pharmacy Transdermal absorption theoretical, use Chinese medicine composition acupoint application treatment Treatment knee joint osseous arthritis (damp arthralgia), can make the various teleneurons of Skin at Acupoints enter active state, constantly promote The nerve of human body, Humoral immunity effect and immunologic function, improved the functional activity of each internal organs organ, conducted by meridians, QI and blood regulating, thus reach good therapeutic effect.
Chinese medicine application therapy is easy, quick, safe and reliable, have no side effect, and cost of medical service is cheap, it is adaptable to primary care Unit is introduced, is promoted, and can be accepted by vast knee joint osseous arthritis (damp arthralgia) patient.Its recovery from illness and obvious effective rate 18.0%, Effective percentage is 72.0%, and total effective rate is 90.0%, is a kind of active drug treating knee joint osseous arthritis.
Detailed description of the invention
Embodiment 1
The external medicine composition for the treatment of knee joint osseous arthritis (damp arthralgia).Its formula and quality are as follows: Fructus Chaenomelis 4g, Fructus Gardeniae 3g, Radix Et Rhizoma Rhei 3g, Herba Taraxaci 4g, Olibanum 2g, Myrrha 2g, Rhizoma Corydalis 6g, Flos Carthami 2g, Radix Angelicae Sinensis 3g, Radix Clematidis 4g, Rhizoma Cibotii 6g.
The using method of the external medicine composition for the treatment of knee joint osseous arthritis (damp arthralgia) is as follows: described Chinese medicine Composition powder is broken into powder, and the amount of every pair of medicine is as follows: Fructus Chaenomelis 4g, Fructus Gardeniae 3g, Radix Et Rhizoma Rhei 3g, Herba Taraxaci 4g, Olibanum 2g, Myrrha 2g, Rhizoma Corydalis 6g, Flos Carthami 2g, Radix Angelicae Sinensis 3g, Radix Clematidis 4g, Rhizoma Cibotii 6g;Adding yellow wine and mix well into pasty state, even application is in medically connecing In the 3 or 6 pieces of strile gauze dressings being subject to, spread on human body one side or the crane of bilateral (may occur in which one side or bilateral knee joint osseous arthritis) Top cave, inside and outside point ex-le 5, indwelling every day was taken off after 8-10 hour.The most concrete consumption is exactly the amount of every pair of medicine.Within 10 days, it is one The individual course for the treatment of, two courses for the treatment of are spaced 2.
Taboo: this Chinese medicine composition skin allergy person is disabled.
The using method of this Chinese medicine composition is as follows: the external application Chinese medicine combination for the treatment of knee joint osseous arthritis (damp arthralgia) Thing is ground into powder, adds yellow wine and mixes well into pasty state, and even application, on medically acceptable 3 or 6 pieces of strile gauze dressings, applies On human body one side or the cave, Heding of bilateral (may occur in which one side or bilateral knee joint osseous arthritis), inside and outside point ex-le 5, every day Indwelling was taken off after 8-10 hour.It within 10 days, it is a course for the treatment of.
Taboo: this Chinese medicine composition skin allergy person is disabled.

Claims (2)

1. the external medicine composition treating damp arthralgia type knee joint osseous arthritis, it is characterised in that: this Chinese medicine composition Raw material composition and quality proportioning as follows: Fructus Chaenomelis: Fructus Gardeniae: Radix Et Rhizoma Rhei: Herba Taraxaci: Olibanum: Myrrha: Rhizoma Corydalis: Flos Carthami: Radix Angelicae Sinensis: Wheeling Celestial: the mass ratio of Rhizoma Cibotii is 4:3:3:4:2:2:6:2:3:4:6.
2. the external medicine composition treating damp arthralgia type knee joint osseous arthritis as claimed in claim 1, it is characterised in that: Its formula and quality are as follows: Fructus Chaenomelis 4g, Fructus Gardeniae 3g, Radix Et Rhizoma Rhei 3g, Herba Taraxaci 4g, Olibanum 2g, Myrrha 2g, Rhizoma Corydalis 6g, Flos Carthami 2g, when Return 3g, Radix Clematidis 4g, Rhizoma Cibotii 6g.
CN201410491208.8A 2014-09-24 2014-09-24 External-use traditional Chinese medicine composition for treating knee osteoarthritis (arthralgia syndrome) Expired - Fee Related CN104324108B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1213551A (en) * 1997-10-07 1999-04-14 何立祥 Medicine for treating heperosteogeny and its prepn. method
CN1462628A (en) * 2003-06-19 2003-12-24 贾松 Pasting medicated plaster for treating bone disease
CN103784890A (en) * 2014-02-28 2014-05-14 刁智刚 Traditional Chinese medicine composition for treating bone diseases

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1213551A (en) * 1997-10-07 1999-04-14 何立祥 Medicine for treating heperosteogeny and its prepn. method
CN1462628A (en) * 2003-06-19 2003-12-24 贾松 Pasting medicated plaster for treating bone disease
CN103784890A (en) * 2014-02-28 2014-05-14 刁智刚 Traditional Chinese medicine composition for treating bone diseases

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