CN103920124A - Sterilizing and skin-protecting chilblain cream - Google Patents
Sterilizing and skin-protecting chilblain cream Download PDFInfo
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Abstract
The invention discloses sterilizing and skin-protecting chilblain cream, and relates to the technical field of daily-use chemical industry. The sterilizing and skin-protecting chilblain cream is prepared from the following raw materials in parts by weight: 2-7 parts of tea oil, 1-3 parts of tea seed cake, 0.5-2 parts of ginger, 35-60 parts of Vaseline, 0.1-2 parts of pepper, 0.5-2.5 parts of sinkiang arnebia root, 2-6 parts of towel gourd and 2.25-13.75 parts of purified water. A preparation method of the sterilizing and skin-protecting chilblain cream comprises the following steps: I, preparing a water extract: (1) preparing a filtrate A, (2) preparing a filtrate B, and (3) combining the filtrates; II, preparing powder; III, preparing a substrate; IV, preparing a finished product. The sterilizing and skin-protecting chilblain cream has the effects of cooling blood, activating blood, relieving swelling and pain, resisting bacteria, diminishing inflammation, removing freckle and wrinkle, preserving moisture, moistening and the like, can be used for treating chilblain, effectively relieving the skin problems of stain, redness and swelling, crack and the like, and treating and preventing chilblain, and is suitable for children, young people as well as middle aged and elderly people.
Description
Technical field
The present invention relates to daily-use chemical industry technical field, particularly a kind of sterilizing skin-protective kibe ointment.
Technical background
Chilblain is a kind of very common dermatosis, is owing to being exposed to limitation, the infringement of erythema inflammation that subzero cold environment causes, mostly occurring in autumn and winter, and especially in temperate climate area, cooling in winter sharply and more common when humid environment.Disease locus mostly is the positions such as finger, toes, heel, thigh, nose, cheek and ear, shows as the symptom such as redness, pruritus, and severe patient can cause blister, ulcer etc.Chilblain is many can cause skin lesion, and malpractice can cause skin to occur that cicatrix is difficult to cure, and affects attractive in appearance.The medicine of traditional treatment chilblain is mainly with improving circulation for object, and it is main that the curative effect of chilblain is also only limited to treatment, adds a large amount of Chinese medicine ingredients more, and onset is slow, toxicity is stronger.And the medicine of traditional treatment chilblain is less to the nursing role of skin, after curing may there is a large amount of pigmentation in chilblain position, and skin fineness is declined, and scar impact is attractive in appearance.At present, treatment chilblain mainly contains following methods: the one, and constitutional treatment, application vasodilation and vitamin E; The 2nd, topical therapeutic, principle is antiinflammatory, detumescence, promote blood circulation, for the not broken person of skin lesion, select 10% camphor spirit, 10% camphor ointment, Oleum Terebinthinae, unguentum perniosis, Mel Adeps Sus domestica ointment (containing 70% Mel, 30% Adeps Sus domestica) etc., also can use Fructus Solani melongenae stalk, Fructus Capsici stalk or Qi Ai, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi) decocting thermal; For ulceration person, first clean with 3% boric acid water, then use 10% camphor ointment, unguentum perniosis, Mel Adeps Sus domestica ointment, 10% YUSHIZHI RUANGAO etc., when secretions is many, can evaporate net for catching birds or fish bag with 3% boric acid water; The 3rd, physiotherapy, adopts ultraviolet erythema amount to irradiate or He-Ne Lasers local irradiation or audio frequency electrotherapy; The 4th, tcm therapy, principle is dispelling cold by warming the meridian, promoting blood circulation to remove obstruction in the collateral, danggui sini decoction or YANGHE TANG etc. for side; The 5th, topical therapeutic, broken person can use Fructus Solani melongenae stalk, and Fructus Capsici stalk or Qi Ai, Exocarpium Benincasae, Cortex cinnamomi japonici (Ramulus Cinnamomi) decocting thermal have broken person and can use Chinese medicine purple cellulitis skin ulcer cream, the removing toxic substances ointment that falls apart.
Chinese patent (number of patent application is 201110341504.6) disclosed " a kind of kibe ointment for the treatment of chilblain ", mainly to count ratio by following raw materials in parts by weight to be prepared from: 10-35 parts of Radix Arnebiae (Radix Lithospermi)s, 10-30 parts, Rhizoma Zingiberis Recens, 20-50 parts of Ramulus Cinnamomi, 10-30 parts, the Radix Rehmanniae, 10-35 parts of Radix Glycyrrhizae Preparatas, 5-20 parts of Radix Angelicae Sinensis, 5-30 parts of the Radix Paeoniae Albas, 5-20 parts of Herba Asaris, 200-600 parts of Saccharum Sinensis Roxb.; This invention is made simple, and therapeutic effect is obvious, and cure rate is high, cheap, has no side effect.
Summary of the invention
The object of the present invention is to provide the effects such as one has removing heat from blood, invigorates blood circulation, reducing swelling and alleviating pain, anti-inflammation, freckle and wrinkle removing, moisturizing moistening, chilblain can be treated, and the kibe ointment due to mottle that chilblain causes, redness, the skin problem such as dry and cracked can be effectively alleviated.
For achieving the above object, the technical measures that the present invention takes are a kind of sterilizing skin-protective kibe ointments of invention, are to be prepared from by following raw material by weight:
Oleum Camelliae 2-7 tea dregs of rice 1-3 Rhizoma Zingiberis Recens 0.5-2 vaseline 35-60
Fructus Capsici 0.1-2 Radix Arnebiae (Radix Lithospermi) 0.5-2.5 Fructus Luffae 2-6 pure water 2.25-13.75;
Its preparation method is as follows:
(i), water extraction liquid preparation:
1., filtrate A preparation: the Rhizoma Zingiberis Recens in above-mentioned raw materials, Fructus Capsici, Fructus Luffae are squeezed the juice respectively, are filtered, merge to obtain filtrate A, for subsequent use;
2., liquor B preparation: the tea dregs of rice in above-mentioned raw materials and Radix Arnebiae (Radix Lithospermi) are mixed, add pure water, supersound process 15-30min, filters, and obtains respectively filtering residue and liquor B, for subsequent use;
3., merging filtrate: by filtrate A for subsequent use and liquor B mix homogeneously, obtain water extraction liquid, for subsequent use;
(ii), powder body preparation: filter residue and drying for subsequent use to water content is less than to 10%, and pulverizing, crosses 180-220 mesh sieve, obtains powder body, for subsequent use;
(iii), matrix preparation: water extraction liquid for subsequent use is heated to boiling, is then cooled to 60-80 DEG C, add Oleum Camelliae for subsequent use, be incubated 5-10min, then add powder body for subsequent use at 60-70 DEG C, homogenizing 5-10min, obtains matrix, for subsequent use;
(iv), finished product preparation: vaseline for subsequent use is heated to fusing, is cooled to 50-70 DEG C, then adds matrix for subsequent use, homogenizing 5-10min, obtains sterilizing skin-protective kibe ointment.
The technical scheme one of its optimization is to be prepared from by following raw material by weight:
Oleum Camelliae 3-6 tea dregs of rice 1.5-2.5 Rhizoma Zingiberis Recens 0.8-1.5 vaseline 40-55
Fructus Capsici 0.5-1.5 Radix Arnebiae (Radix Lithospermi) 0.75-1.75 Fructus Luffae 3-5 pure water 3.5-10.
The technical scheme two of its optimization is to be prepared from by following raw material by weight:
Oleum Camelliae 4-5 tea dregs of rice 1.7-2 Rhizoma Zingiberis Recens 1-1.25 vaseline 45-50
Fructus Capsici 0.8-1.0 Radix Arnebiae (Radix Lithospermi) 1.25-1.5 Fructus Luffae 3.5-4.5 pure water 4.5-9.
Raw material of the present invention comprises that Oleum Camelliae (Camellia oleifera Abel) is to refine by Camellia oil fruit the edible oil forming, be rich in the unsaturated fatty acid such as oleic acid, linoleic acid, not containing harmful materials such as erucic acid, cholesterol, there is the title of " east olive oil "; In addition, the bioactive substances such as vitamin E, Squalene, tea polyphenols and camellianin element in Oleum Camelliae, are also rich in, there is the effects such as clearing away heat and eliminating dampness, reducing swelling and alleviating pain, anti-inflammation, can ultraviolet light, prevent sunburn and wrinkle removing stricture of vagina, skin is had to lubricated, moisture-keeping function preferably, desalination spot is had to good effect.The tea dregs of rice are remaining slags after the oil expression of Camellia oil fruit, contain many bioactive substances as tea saponin, active polysaccharide, aminoacid etc., wherein tea saponin content is higher, is about 10%-20%, it is a kind of natural nonionic surfactant, has the effects such as analgesia, antiinflammatory, itch-stopping bactericidal.Rhizoma Zingiberis Recens (Zingiber officinale Roscoe) is the tuber stem of ginger, and warming spleen and stomach for dispelling cold, has the effect such as disinfecting detoxifying, reducing swelling and alleviating pain, and skin sore, freckle and drying property skin etc. are also had to certain therapeutic effect.Vaseline (vaseline) is a kind of mineral wax, and it can not be absorbed by the skin, but can form protecting film one in skin surface, and the difficult evaporation of moisture of skin is scattered and disappeared, and has good moistening effect, meanwhile, also has the effect of removing scar.Fructus Capsici (chillies) can warming the stomach be dispeled cold, blood circulation promoting, alleviation skin pain, has antiinflammatory and antioxidation, and external can treating chilblain.Radix Arnebiae (Radix Lithospermi) (Lithospermum erythrorhizon) removing heat from blood, invigorates blood circulation, and removing toxic substances rash, has the effect of significant anti-acne and antiinflammatory.Fructus Luffae [Luffa cylindrica (Linn.) Roem] removing pathogenic heat from blood and toxic substance from the body; contain lymphatic temperament, wood glue, citrulline, xylan and can prevent the composition such as the vitamin B group of skin aging and the vitamin C of skin whitening; can protect skin, eliminate speckle, make that skin is pure white, delicate, raising skin elasticity.Pure water is pure, clean, does not contain the water of impurity or antibacterial.
Thereby sterilizing skin-protective kibe ointment of the present invention, compared with prior art, has following characteristics:
The one, secondary little, the good absorbing, rapid-action of poison.The selected composition of the present invention mostly is integration of edible and medicinal herbs attribute material, and its interpolation has no side effect to human body, without irritated.Add natural Oleum Camelliae, wherein unsaturated fatty acid content is up to more than 90%, and absorption of human body utilization rate is high, adopts Oleum Camelliae and various integration of edible and medicinal herbs composition to cooperatively interact, and makes product good absorbing, rapid-action.
The 2nd, green, environmental protection, pollution-free.Primary raw material of the present invention adopts the Oleum Camelliae and the tea dregs of rice that originate from the xylophyta mountain tea Culture in remote mountains, and in growth course, no pesticide grown chemical fertilizer, heavy metal free pollute; The compositions such as the Rhizoma Zingiberis Recens, Radix Arnebiae (Radix Lithospermi), Fructus Capsici, Fructus Luffae adopting all belong to integration of edible and medicinal herbs food, and cost is low, toxicity is little, pollution is few; In the course of processing, the present invention does not add any antiseptic and essence, and product pure natural is manufactured, and belongs to a real green, healthy free of contamination treatment chilblain class medicine.
The 3rd, prevention, treatment, the unification of maintenance triple effect.Sterilizing skin-protective kibe ointment of the present invention, adopt above-mentioned many raw materials to share, there is removing heat from blood, invigorate blood circulation, the effect such as reducing swelling and alleviating pain, anti-inflammation, freckle and wrinkle removing, moisturizing moistening, can effectively prevent and treat chilblain, and in treatment, promote skin regeneration, improve skin growing environment, skin is had to effect moist, that repair, therefore can effectively improve the symptom such as chapped skin, cicatrix causing due to chilblain, really play the effect of prevention, treatment, the unification of maintenance triple effect.
Sterilizing skin-protective kibe ointment quality better of the present invention, effective ingredient activity is higher.Product standard meets QB/T1875-2004, and its indices testing result is as shown in table 1 below, and sanitary index testing result is as shown in table 2.
Each index testing result of table 1 sterilizing skin-protective kibe ointment of the present invention
| Composition | Content |
| Tea saponin (milligram/g) | 30.5-40.8 |
| Squalene (milligram/g) | 1.53-2.11 |
| V E(microgram/g) | 167-184 |
| Unsaturated fatty acid (milligram/g) | 242-351 |
The sanitary index testing result of table 2 sterilizing skin-protective kibe ointment of the present invention
(note: ND represents not detect)
Sterilizing skin-protective kibe ointment of the present invention has done clinical verification test for the effect of its treatment chilblain, and process of the test and result are as follows:
1, EXPERIMENTAL DESIGN
Choose easy frostbitten child and teenager in backlands district, Henan, E Beidiqu, area, the Three Eastern Provinces as subjects, age distribution is tested amounting to 108 people (each 54 people of men and women) in 3-18 year.All there is chilblain and have ulceration phenomenon (that is: II degree--chickenpox chilblain) for examination object.The design of test number is as shown in table 3.Every group of subjects is all selected from identical school, respectively organizes personnel's living environment identical.Control sample is only smeared vaseline skin protection, not administering therapeutic and anti-frostbite class medicine.
The design of table 3 test number
Each subjects is smeared sterilizing skin-protective kibe ointment of the present invention in chilblain position, use continuously 3 months, investigates its therapeutic effect to chilblain.Enter every year when local temperature on average is lower than 15 DEG C after autumn and start to smear sterilizing skin-protective kibe ointment of the present invention, verify its preventive effect to chilblain, whether tracking test 2 years, investigate chilblain and recur.
Treatment to chilblain and preventive effect evaluation criterion are as shown in following table 4 and table 5.
Table 4 is to treatment of perniosis effect assessment standard
| Phenomenon | Effect score |
| Red swelling of the skin, chickenpox | Invalid |
| Skin is without chickenpox, redness, the dark red purple of color | ★★ |
| Skin is without chickenpox, and redness disappears, color pinkiness | ★★★ |
| Skin is without redness, and other site color of chilblain place and skin approach | ★★★★ |
| Skin smooth exquisiteness, without red and swollen, the phenomenon such as dry and cracked, color is normal | ★★★★★ |
The preventive effect evaluation criterion of table 5 to chilblain
2 result of the tests
After tracking test 2 years, the treatment of sterilizing skin-protective kibe ointment of the present invention to chilblain and preventive effect are as shown in table 6 and table 7.
The therapeutic effect of table 6 sterilizing skin-protective kibe ointment of the present invention to chilblain
The preventive effect of table 7 sterilizing skin-protective kibe ointment of the present invention to chilblain
As shown in Table 6, sterilizing skin-protective kibe ointment of the present invention all has good therapeutic effect to three, three areas age bracket for examination object, Heilongjiangdistrict wintry weather cold, and therapeutic effect is slightly poor compared with other two areas, but significantly better than control sample.Sterilizing skin-protective kibe ointment of the present invention to the redness causing because of chilblain, ulcer, very itch, the symptom such as pigmentation has good curative effect, after using, cure patient skin majority and become smooth exquisiteness.As shown in Table 7, continue to use after sterilizing skin-protective kibe ointment of the present invention, most of patients chilblain recurrence probability reduces, ulcer phenomenon disappears, the inflammation person such as occur individually itching, red and swollen continues to smear transference cure after sterilizing skin-protective kibe ointment of the present invention, and skin gloss increases, without the phenomenon such as withered.Matched group is easily recurrence.Sterilizing skin-protective kibe ointment of the present invention has obvious preventive effect to chilblain as can be seen here.
Specific implementation method
Below in conjunction with specific embodiment, the present invention will be further described.Explanation is below the mode exemplifying, but protection scope of the present invention is not limited to this.
Embodiment mono-:
The sterilizing skin-protective kibe ointment of the present embodiment, its preparation method is as follows:
(i), get the raw materials ready: get respectively Oleum Camelliae 2g, tea dregs of rice 1g, Rhizoma Zingiberis Recens 0.5g, vaseline 35g, Fructus Capsici 0.1g, Radix Arnebiae (Radix Lithospermi) 0.5g, Fructus Luffae 2g, pure water 2.25g, for subsequent use;
(i), water extraction liquid preparation:
1., filtrate A preparation: the Rhizoma Zingiberis Recens in above-mentioned raw materials, Fructus Capsici, Fructus Luffae are squeezed the juice respectively, are filtered, merge to obtain filtrate A, for subsequent use;
2., liquor B preparation: the tea dregs of rice in above-mentioned raw materials and Radix Arnebiae (Radix Lithospermi) are mixed, add pure water, supersound process 15min, filters, and obtains respectively filtering residue and liquor B, for subsequent use;
3., merging filtrate: by filtrate A for subsequent use and liquor B mix homogeneously, obtain water extraction liquid, for subsequent use;
(ii), powder body preparation: be 9.5% by filter residue and drying for subsequent use to water content, pulverizing, crosses 200 mesh sieves, obtains powder body, for subsequent use;
(iii), matrix preparation: water extraction liquid for subsequent use is heated to boiling, is then cooled to 65 DEG C, add Oleum Camelliae for subsequent use, be incubated 8min, then add powder body for subsequent use at 65 DEG C, homogenizing 10min, obtains matrix, for subsequent use;
(iv), finished product preparation: vaseline for subsequent use is heated to fusing, is cooled to 55 DEG C, then adds matrix for subsequent use, homogenizing 7min, obtains sterilizing skin-protective kibe ointment, is finished product after subpackage.
This product has no side effect, good absorbing, rapid-action, green health is pollution-free, the effect of skin after freezing with skin protection reparation in prevention and treatment chilblain, and product quality meets the requirement of QB/T1875-2004.
Embodiment bis-:
The sterilizing skin-protective kibe ointment of the present embodiment, its preparation method is as follows:
(i) `, get the raw materials ready: get respectively Oleum Camelliae 4g, tea dregs of rice 1.5g, Rhizoma Zingiberis Recens 1g, vaseline 55g, Fructus Capsici 1.3g, Radix Arnebiae (Radix Lithospermi) 1.5g, Fructus Luffae 4g, pure water 6g, for subsequent use;
(i), water extraction liquid preparation:
1., filtrate A preparation: the Rhizoma Zingiberis Recens in above-mentioned raw materials, Fructus Capsici, Fructus Luffae are squeezed the juice respectively, are filtered, merge to obtain filtrate A, for subsequent use;
2., liquor B preparation: the tea dregs of rice in above-mentioned raw materials and Radix Arnebiae (Radix Lithospermi) are mixed, add pure water, supersound process 25min, filters, and obtains respectively filtering residue and liquor B, for subsequent use;
3., merging filtrate: by filtrate A for subsequent use and liquor B mix homogeneously, obtain water extraction liquid, for subsequent use;
(ii), powder body preparation: be 8.0% by filter residue and drying for subsequent use to water content, pulverizing, crosses 200 mesh sieves, obtains powder body, for subsequent use;
(iii), matrix preparation: water extraction liquid for subsequent use is heated to boiling, is then cooled to 65 DEG C, add Oleum Camelliae for subsequent use, be incubated 8min, then add powder body for subsequent use at 65 DEG C, homogenizing 10min, obtains matrix, for subsequent use;
(iv), finished product preparation: vaseline for subsequent use is heated to fusing, is cooled to 55 DEG C, then adds matrix for subsequent use, homogenizing 7min, obtains sterilizing skin-protective kibe ointment, is finished product after subpackage.
This product has no side effect, good absorbing, rapid-action, green health is pollution-free, the effect of skin after freezing with skin protection reparation in prevention and treatment chilblain, and product quality meets the requirement of QB/T1875-2004.
Embodiment tri-:
The sterilizing skin-protective kibe ointment of the present embodiment, its preparation method is as follows:
(i) `, get the raw materials ready: get respectively Oleum Camelliae 7g, tea dregs of rice 3g, Rhizoma Zingiberis Recens 2g, vaseline 60g, Fructus Capsici 2g, Radix Arnebiae (Radix Lithospermi) 2.5g, Fructus Luffae 6g, pure water 13.75g, for subsequent use;
(i), water extraction liquid preparation:
1., filtrate A preparation: the Rhizoma Zingiberis Recens in above-mentioned raw materials, Fructus Capsici, Fructus Luffae are squeezed the juice respectively, are filtered, merge to obtain filtrate A, for subsequent use;
2., liquor B preparation: the tea dregs of rice in above-mentioned raw materials and Radix Arnebiae (Radix Lithospermi) are mixed, add pure water, supersound process 15min, filters, and obtains respectively filtering residue and liquor B, for subsequent use;
3., merging filtrate: by filtrate A for subsequent use and liquor B mix homogeneously, obtain water extraction liquid, for subsequent use;
(ii), powder body preparation: be 9.0% by filter residue and drying for subsequent use to water content, pulverizing, crosses 200 mesh sieves, obtains powder body, for subsequent use;
(iii), matrix preparation: water extraction liquid for subsequent use is heated to boiling, is then cooled to 65 DEG C, add Oleum Camelliae for subsequent use, be incubated 8min, then add powder body for subsequent use at 65 DEG C, homogenizing 10min, obtains matrix, for subsequent use;
(iv), finished product preparation: vaseline for subsequent use is heated to fusing, is cooled to 55 DEG C, then adds matrix for subsequent use, homogenizing 7min, obtains sterilizing skin-protective kibe ointment, is finished product after subpackage.
This product has no side effect, good absorbing, rapid-action, green health is pollution-free, the effect of skin after freezing with skin protection reparation in prevention and treatment chilblain, and product quality meets the requirement of QB/T1875-2004.
Sterilizing skin-protective kibe ointment of the present invention, both can be used for treating chilblain, also can be used for anti-frostbite; Both be applicable to child and adolescence, and be also applicable to middle-aged and elderly people and use.
Claims (3)
1. a sterilizing skin-protective kibe ointment, it is characterized in that being prepared from by following raw material by weight:
Oleum Camelliae 2-7 tea dregs of rice 1-3 Rhizoma Zingiberis Recens 0.5-2 vaseline 35-60
Fructus Capsici 0.1-2 Radix Arnebiae (Radix Lithospermi) 0.5-2.5 Fructus Luffae 2-6 pure water 2.25-13.75;
Its preparation method is as follows:
(i), water extraction liquid preparation:
1., filtrate A preparation: the Rhizoma Zingiberis Recens in above-mentioned raw materials, Fructus Capsici, Fructus Luffae are squeezed the juice respectively, are filtered, merge to obtain filtrate A, for subsequent use;
2., liquor B preparation: the tea dregs of rice in above-mentioned raw materials and Radix Arnebiae (Radix Lithospermi) are mixed, add pure water, supersound process 15-30min, filters, and obtains respectively filtering residue and liquor B, for subsequent use;
3., merging filtrate: by filtrate A for subsequent use and liquor B mix homogeneously, obtain water extraction liquid, for subsequent use;
(ii), powder body preparation: filter residue and drying for subsequent use to water content is less than to 10%, and pulverizing, crosses 180-220 mesh sieve, obtains powder body, for subsequent use;
(iii), matrix preparation: water extraction liquid for subsequent use is heated to boiling, is then cooled to 60-80 DEG C, add Oleum Camelliae for subsequent use, be incubated 5-10min, then add powder body for subsequent use at 60-70 DEG C, homogenizing 5-10min, obtains matrix, for subsequent use;
(iv), finished product preparation: vaseline for subsequent use is heated to fusing, is cooled to 50-70 DEG C, then adds matrix for subsequent use, homogenizing 5-10min, obtains sterilizing skin-protective kibe ointment.
2. sterilizing skin-protective kibe ointment according to claim 1, it is characterized in that being prepared from by following raw material by weight:
Oleum Camelliae 3-6 tea dregs of rice 1.5-2.5 Rhizoma Zingiberis Recens 0.8-1.5 vaseline 40-55
Fructus Capsici 0.5-1.5 Radix Arnebiae (Radix Lithospermi) 0.75-1.75 Fructus Luffae 3-5 pure water 3.5-10.
3. sterilizing skin-protective kibe ointment according to claim 1 and 2, it is characterized in that being prepared from by following raw material by weight:
Oleum Camelliae 4-5 tea dregs of rice 1.7-2 Rhizoma Zingiberis Recens 1-1.25 vaseline 45-50
Fructus Capsici 0.8-1.0 Radix Arnebiae (Radix Lithospermi) 1.25-1.5 Fructus Luffae 3.5-4.5 pure water 4.5-9.
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| CN107243072A (en) * | 2017-04-28 | 2017-10-13 | 贵州益寿农业科技有限公司 | A kind of skin care kibe ointment and preparation method thereof |
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| CN105456157B (en) * | 2015-12-11 | 2019-01-25 | 泉州市福达科技咨询有限公司 | A kind of pure natural tea seed skin-care facial mask and preparation method thereof |
| CN107243072A (en) * | 2017-04-28 | 2017-10-13 | 贵州益寿农业科技有限公司 | A kind of skin care kibe ointment and preparation method thereof |
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| CN103920124B (en) | 2016-05-11 |
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