CN104815029B - A kind of drug and preparation method thereof for treating tinea pedis - Google Patents
A kind of drug and preparation method thereof for treating tinea pedis Download PDFInfo
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- CN104815029B CN104815029B CN201510227096.XA CN201510227096A CN104815029B CN 104815029 B CN104815029 B CN 104815029B CN 201510227096 A CN201510227096 A CN 201510227096A CN 104815029 B CN104815029 B CN 104815029B
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Abstract
The invention discloses a kind of drug for treating tinea pedis, it includes following component that the raw material of the drug is counted in parts by weight：10~30 parts of hairyvein agrimony, 1~10 part of kuh-seng, 1~3 part of radix euphorbiae lantu, 1~3 part of Sulfur, 1~5 part of stiff silkworm, 10~30 parts of uncaria, 10~30 parts of Chinese trumpet creeper, 10~30 parts of corter pseudolaricis, 1~10 part of plum blossom, 10~20 parts of Radix Glycyrrhizae, 10~20 parts of mulberry leaf.The present invention treats the drug of tinea pedis, and dispelling wind and eliminating dampness, desinsection is antipruritic to dispel skin wet poison in vitro, so that skin lesion is gradually reduced to stubborn dermatitis and all subsides, the later stage promotes epidermis dermis growth.Tinea pedis is fundamentally cured, recurrent exerbation is avoided.It is significant in efficacy, and treatment cycle is short, mitigates the pain of patient.The preparation method of tinea pedis drug of the present invention is simple, easily operated, convenient for promoting.
Description
Technical field
The present invention relates to the field of Chinese medicines, more particularly to a kind of drug and preparation method thereof for treating tinea pedis.
Background technology
Tinea pedis (popular name " athlete's foot ", tinea pedis), is that fungal infection causes, and skin lesion is often first unilateral (i.e. single foot)
Occur, just offside is arrived in infection after several weeks or several months.Blister mainly appears on toe abdomen and toe side, is most commonly between three or four toes, vola
Also it may occur in which, be deep-seated phlysis, can gradually be fused into bleb.The skin lesion of tinea pedis has a feature, i.e. clear border, can
Gradually extend to the outside.Because of progression of the disease or scratching, rotten to the corn, sepage may occur in which, even, there is warts etc. in bacterium infection.
Tinea pedis is the foot dermatosis caused by pathogenic fungus, has infectiousness.Tinea pedis is popular in the whole world,
Subtropical and tropical zones are more universal.In China, the incidence of tinea pedis is also quite high.Without sebum between the vola and toe of people
Gland, to lack the aliphatic acid for inhibiting skin filamentous fungi, physiological defense function is poor, and the sweat gland of skin at these positions is very
It is abundant, it perspires relatively more, air circulation is poor in addition, part damp warm, is conducive to the growth of filamentous fungi.In addition, vola
Area skin cuticula is thicker, and the keratin in cuticula is the abundant nutrition substance of fungi, is conducive to the growth of fungi.
The drug products type for the treatment of tinea pedis is various currently on the market, but effect is imprecise, and treatment cycle is long.
Being disclosed in the information of the background technology part, it is only intended to increase understanding of the overall background of the invention, without answering
It has been the prior art well known to persons skilled in the art when being considered as recognizing or imply that the information is constituted in any form.
Invention content
The purpose of the present invention is to provide a kind of drugs for treating tinea pedis, to overcome the existing drug therapy tinea pedis period
Long, the inapparent disadvantage of curative effect.
To achieve the above object, the present invention provides a kind of drug for treating tinea pedis, the raw material of the drug is in parts by weight
Meter includes following component：10~30 parts of hairyvein agrimony, 1~10 part of kuh-seng, 1~3 part of radix euphorbiae lantu, 1~3 part of Sulfur, 1~5 part of stiff silkworm, hook
10~30 parts of rattan, 10~30 parts of Chinese trumpet creeper, 10~30 parts of corter pseudolaricis, 1~10 part of plum blossom, 10~20 parts of Radix Glycyrrhizae, mulberry leaf 10~20
Part.
Preferably, in above-mentioned technical proposal, the drug of the treatment tinea pedis, the raw material medicaments in part by weight number meter of the drug
Including following component：15 parts of hairyvein agrimony, 5 parts of kuh-seng, 2 parts of radix euphorbiae lantu, 2 parts of Sulfur, 3 parts of stiff silkworm, 15 parts of uncaria, 20 parts of Chinese trumpet creeper,
18 parts of corter pseudolaricis, 5 parts of plum blossom, 14 parts of Radix Glycyrrhizae, 16 parts of mulberry leaf.
Preferably, in above-mentioned technical proposal, the drug of the treatment tinea pedis, the drug can be made into spray or paste.
A kind of preparation method of drug that treating tinea pedis, the drug are made spray, include the following steps：
(1) add water to decoct bulk pharmaceutical chemicals, first boil with high heat again with 30~60min is cooked by slow fire, then go filtrate,
The remaining dregs of a decoction；
(2) add water to decoct again the dregs of a decoction of the step (1), first boil with high heat again be cooked by slow fire 30~
The liquid decocted twice is mixed to get raw material liquid by 60min.
A kind of preparation method of drug that treating tinea pedis, the drug are made paste, include the following steps, by raw material medicinal powder
It is broken, bulk pharmaceutical chemicals are mixed with borneol, paste auxiliary material then, paste is made.
Preferably, in above-mentioned technical proposal, the paste auxiliary material includes vaseline, liquid paraffin, vaseline and lanolin
One kind in mixture.
Preferably, in above-mentioned technical proposal, it includes 2~8 parts that the borneol is counted in parts by weight.
The bulk pharmaceutical chemicals pharmacological property that the present invention treats tinea pedis drug is as follows：
Hairyvein agrimony：Astringing to arrest bleeding, preventing malaria, stop dysentery, removing toxic substances.For hemoptysis, spit blood, metrostaxis, malaria, bloody flux, de- power
Internal lesion caused by overexertion, carbuncle sore tumefacting virus, under pruritus vulvae band.
Kuh-seng：Heat-clearing and damp-drying drug, desinsection, diuresis.It for hot dysentery, has blood in stool, jaundice renal shutdown, leukorrhea with reddish discharge, swelling of vulva pruritus vulvae is wet
Rash, wet sore, pruitus, mange leprosy；Control trichomonas vaginitis outside.
Radix euphorbiae lantu：Dissipating bind is relieved oedema or abdominal distension through diuresis or purgation, analgesic, desinsection.For aqueous vapor swelling, scrofula；Scabies, tinea are controlled in external application, kill fly, maggot.
Sulfur：External application removing toxic substances desinsection treats sore；Mends fire supporing yang defaecation for oral administration.It controls outside for mange, the favus of the scalp, cloudy subcutaneous ulcer malignant sore；It is interior
Take, void asthma asthma of cold type cold enough in impotence, cold of insufficiency type constipation.
Stiff silkworm：Dispelling wind and relieving convulsion, reducing phlegm and resolving masses.For convulsion, abscess of throat, pruitus, submandibular lymph nodes is scorching, face
Neural paralysis.
Uncaria：The flat liver of heat-clearing, dispelling wind and relieving convulsion.For dizziness of having a headache, dysphoric cold, twitch, pre-eclampsia；High blood
Pressure.
Chinese trumpet creeper：Cool blood, stagnation resolvation, wind-dispelling.For irregular menstruation, Jing Bi wei lumps in the abdomen, postpartum breast is swollen, and rubella is rubescent, skin scabies
Itch, acne.
Corter pseudolaricis：Anti-Puritic and insecticidal.For trick tinea, neurodermatitis, eczema, leprosy dysentery head.
Plum blossom：Open Yu Hezhong, resolving sputum, removing toxic substances.For gloomy vexed, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach, globus hysteriocus, scrofula sore.
Radix Glycyrrhizae：It invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, burnout is weary
Power, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus alleviate drug toxicity, strong.
Mulberry leaf：Dispelling wind and heat from the body, clearing away the lungheat and moisturizing are clear liver and improved vision.For anemopyretic cold, lung-heat type cough, dizziness headache, hot eyes dusk
Flower.
Borneol：Inducing resuscitation of having one's ideas straightened out, clearing away heat to and alleviating pain.It faints for pyreticosis coma, convulsion, apoplexy coma due to blocking of the respiratory system, bstruction of the circulation of vital energy is fainted cruelly, middle evil is gone into a coma,
Hot eyes, aphtha, abscess of throat, duct are suppurated.
Compared with prior art, the present invention has the advantages that：The present invention treats the drug of tinea pedis, and wind-dispelling removes
Wet, desinsection is antipruritic to dispel skin wet poison in vitro, so that skin lesion is gradually reduced to stubborn dermatitis and all subsides, the later stage promotes epidermis dermis life
It is long.Tinea pedis is fundamentally cured, recurrent exerbation is avoided.It is significant in efficacy, and treatment cycle is short, mitigates the pain of patient.The present invention
The preparation method of tinea pedis drug is simple, easily operated, convenient for promoting.
Specific implementation mode
With reference to specific embodiment, the specific implementation mode of the present invention is described in detail, it is to be understood that this hair
Bright protection domain is not restricted by specific implementation.
Embodiment 1
A kind of drug for treating tinea pedis, it includes following component that the raw material of the drug is counted in parts by weight：10 parts of hairyvein agrimony, hardship
1 part of ginseng, 1 part of radix euphorbiae lantu, 1 part of Sulfur, 1 part of stiff silkworm, 10 parts of uncaria, 10 parts of Chinese trumpet creeper, 10 parts of corter pseudolaricis, 1 part of plum blossom, Radix Glycyrrhizae 10
Part, 10 parts of mulberry leaf.
A kind of preparation method of drug that treating tinea pedis, the drug are made spray, include the following steps：
(1) add water to decoct bulk pharmaceutical chemicals, first boil with high heat again with 30min is cooked by slow fire, then go filtrate, it is remaining
The dregs of a decoction；
(2) add water to decoct again the dregs of a decoction of the step (1), first boil with high heat again with being cooked by slow fire 30min,
The liquid decocted twice is mixed to get raw material liquid, liquid is then wanted to dispense finished product.
Embodiment 2
A kind of drug for treating tinea pedis, it includes following component that the raw material of the drug is counted in parts by weight：15 parts of hairyvein agrimony, hardship
5 parts of ginseng, 2 parts of radix euphorbiae lantu, 2 parts of Sulfur, 3 parts of stiff silkworm, 15 parts of uncaria, 20 parts of Chinese trumpet creeper, 18 parts of corter pseudolaricis, 5 parts of plum blossom, Radix Glycyrrhizae 14
Part, 16 parts of mulberry leaf.
A kind of preparation method of drug that treating tinea pedis, the drug are made spray, include the following steps：
(1) add water to decoct bulk pharmaceutical chemicals, first boil with high heat again with 50min is cooked by slow fire, then go filtrate, it is remaining
The dregs of a decoction；
(2) add water to decoct again the dregs of a decoction of the step (1), first boil with high heat again with being cooked by slow fire 40min,
The liquid decocted twice is mixed to get raw material liquid, liquid is then wanted to dispense finished product.
Embodiment 3
A kind of drug for treating tinea pedis, it includes following component that the raw material of the drug is counted in parts by weight：30 parts of hairyvein agrimony, hardship
10 parts of ginseng, 3 parts of radix euphorbiae lantu, 3 parts of Sulfur, 5 parts of stiff silkworm, 30 parts of uncaria, 30 parts of Chinese trumpet creeper, 30 parts of corter pseudolaricis, 10 parts of plum blossom, Radix Glycyrrhizae 20
Part, 20 parts of mulberry leaf.
A kind of preparation method of drug that treating tinea pedis, the drug are made spray, include the following steps：
(1) add water to decoct bulk pharmaceutical chemicals, first boil with high heat again with 60min is cooked by slow fire, then go filtrate, it is remaining
The dregs of a decoction；
(2) add water to decoct again the dregs of a decoction of the step (1), first boil with high heat again with being cooked by slow fire 60min,
The liquid decocted twice is mixed to get raw material liquid, liquid is then wanted to dispense finished product.
Embodiment 4
A kind of drug for treating tinea pedis, it includes following component that the raw material of the drug is counted in parts by weight：18 parts of hairyvein agrimony, hardship
8 parts of ginseng, 1 part of radix euphorbiae lantu, 2 parts of Sulfur, 3 parts of stiff silkworm, 23 parts of uncaria, 16 parts of Chinese trumpet creeper, 18 parts of corter pseudolaricis, 5 parts of plum blossom, Radix Glycyrrhizae 13
Part, 13 parts of mulberry leaf, 3 parts of borneol.
A kind of preparation method of drug that treating tinea pedis, the drug are made paste, include the following steps, by raw material medicinal powder
It is broken, bulk pharmaceutical chemicals are mixed with borneol, paste auxiliary material then, paste is made.
Preferably, the paste auxiliary material includes one kind in vaseline, liquid paraffin, vaseline and lanolin mixture.
The application method of drug of the present invention is as follows：
It when pharmaceutical dosage form is spray, sprays 4~5 times daily, with the liquid and hot water by 1 before sleeping:After 10 ratio allotment
Foot is steeped, soaking time is 30min or more, 10 days as a treatment course.
Pharmaceutical dosage form is paste, is applied to affected part daily 2~3 times, 15 days as a treatment course.
Therapeutic effect is as follows：
Clinical test is carried out to 200 patients, wherein man 104, female 96, age bracket is between 20~50 years old.It is divided to two
Group is tested, every group of 100 people, drug made from first group of embodiment 2 used, and second group uses embodiment 4 to be made
Drug.
Diagnostic criteria：
Clinical manifestation is to be divided into three type of scales of skin that peel off angling, bubble and intertrigo, is in clinically that scales of skin that peel off keratinization type shows, just more
Rise between hand, toe, there is deep-seated blister repeatedly in foot and its lateral margin, with apparent itch, furfur after blister liquid is dry, range day flaring
Greatly, pachylosis thickens at furfur, and the wide depth of dermatoglyph loses normal gloss and flexibility, strip furfur occurs, touches thick
Rough, long entire brothers slap involvement.To winter, pain is felt in dry and cracked aggravation.Cuticula thickens, is coarse, furfur, dry and cracked, nothing
Sweat, such as bark shape.
Criterion of therapeutical effect：
Clinical recovery：Mycology examination is negative at skin lesion, and skin lesion disappears；It is effective：Fungus examination is turned out cloudy at skin lesion, skin
Skin damage recession 80%；Effectively：Fungus examination is turned out cloudy at skin lesion, skin lesion recession 60%；In vain：Fungus examination sun at skin lesion
Property, skin lesion recession less than 30% or it is counter see increase.
Two groups for the treatment of results and curative effect compare, as shown in table 1.
1 two groups for the treatment of results of table and curative effect compare
| Group | Number | It cures | It is effective | Effectively | In vain | Total effective rate |
| First group | 100 | 83 | 15 | 2 | 0 | 100% |
| Second group | 100 | 82 | 15 | 3 | 0 | 100% |
Pay a return visit tracking
First group of recurrence rate is 2%, and second group is 3%.
The description of the aforementioned specific exemplary embodiment to the present invention is in order to illustrate and illustration purpose.These descriptions
It is not wishing to limit the invention to disclosed precise forms, and it will be apparent that according to the above instruction, can much be changed
And variation.The purpose of selecting and describing the exemplary embodiment is that explaining the specific principle of the present invention and its actually answering
With so that those skilled in the art can realize and utilize the present invention a variety of different exemplary implementation schemes and
Various chooses and changes.The scope of the present invention is intended to be limited by claims and its equivalents.
Claims (6)
1. a kind of drug for treating tinea pedis, which is characterized in that the raw material of the drug is counted in parts by weight, is made of following components：
10 ~ 30 parts of hairyvein agrimony, 1 ~ 10 part of kuh-seng, 1 ~ 3 part of radix euphorbiae lantu, 1 ~ 3 part of Sulfur, 1 ~ 5 part of stiff silkworm, 10 ~ 30 parts of uncaria, Chinese trumpet creeper 10 ~
30 parts, 10 ~ 30 parts of corter pseudolaricis, 1 ~ 10 part of plum blossom, 10 ~ 20 parts of Radix Glycyrrhizae, 10 ~ 20 parts of mulberry leaf；Spray or paste is made in the drug.
2. the drug for the treatment of tinea pedis according to claim 1, which is characterized in that the raw material medicaments in part by weight number of the drug
Meter, is made of following components：15 parts of hairyvein agrimony, 5 parts of kuh-seng, 2 parts of radix euphorbiae lantu, 2 parts of Sulfur, 3 parts of stiff silkworm, 15 parts of uncaria, Chinese trumpet creeper
20 parts, 18 parts of corter pseudolaricis, 5 parts of plum blossom, 14 parts of Radix Glycyrrhizae, 16 parts of mulberry leaf.
3. a kind of preparation method of the drug for the treatment of tinea pedis according to claim 1, which is characterized in that the drug is made
Spray includes the following steps：
（1）Bulk pharmaceutical chemicals plus water are decocted, first boils with high heat again with 30 ~ 60min is cooked by slow fire, then goes filtrate, it is remaining
The dregs of a decoction；
（2）By the step（1）The dregs of a decoction add water to be decocted again, first boil with high heat again with being cooked by slow fire 30 ~ 60min,
The liquid decocted twice is mixed to get raw material liquid.
4. a kind of preparation method of the drug for the treatment of tinea pedis according to claim 1, which is characterized in that the drug is made
Paste includes the following steps, bulk pharmaceutical chemicals are crushed, and then mixes bulk pharmaceutical chemicals with borneol, paste auxiliary material, paste is made.
5. the preparation method of the drug for the treatment of tinea pedis according to claim 4, which is characterized in that the paste auxiliary material includes all
One kind in intellectual circle, liquid paraffin, vaseline and lanolin mixture.
6. the preparation method of the drug for the treatment of tinea pedis according to claim 4, which is characterized in that the borneol is in parts by weight
It is calculated as 2 ~ 8 parts.
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| CN201510227096.XA CN104815029B (en) | 2015-05-06 | 2015-05-06 | A kind of drug and preparation method thereof for treating tinea pedis |
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| CN104815029B true CN104815029B (en) | 2018-09-21 |
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| CN111265578A (en) * | 2020-03-19 | 2020-06-12 | 坤承(北京)健康管理有限公司 | Antibacterial spray for treating beriberi and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101518600A (en) * | 2009-03-30 | 2009-09-02 | 李燕 | Chinese medicinal composition for treating bacterial or fungal dermatosis and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004196669A (en) * | 2002-12-16 | 2004-07-15 | Kose Corp | Melanocyte proliferation inhibitor and skin care preparation for external use comprising the same |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101518600A (en) * | 2009-03-30 | 2009-09-02 | 李燕 | Chinese medicinal composition for treating bacterial or fungal dermatosis and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 祛风止痒凌霄花;章茂森;《中国中医药报》;20060511;第007版 * |
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