CN109908111A - A kind of rhinitis plaster and preparation method thereof - Google Patents
A kind of rhinitis plaster and preparation method thereof Download PDFInfo
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- CN109908111A CN109908111A CN201910295202.6A CN201910295202A CN109908111A CN 109908111 A CN109908111 A CN 109908111A CN 201910295202 A CN201910295202 A CN 201910295202A CN 109908111 A CN109908111 A CN 109908111A
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Abstract
The present invention relates to a kind of rhinitis plasters, including the following raw material to be made: Moschus, cortex cinnamomi, the root of Dahurain angelica, pinellia, vinegar rhizoma corydalis, asarum, Rhizoma Et Radix Notopterygii, Korean ginseng, radix saposhnikoviae, aconiti preparata,radix, Radix Salviae Miltiorrhizae, radix aucklandiae, the root of three-nerved spicebush and flos caryophylli.Rhinitis plaster of the invention passes through the synergistic effect of each raw material, has stronger penetrating power, lesion of going directly, a surname's clearing the nasal passage, relieving cough and asthma, warming yang and benefiting qi effect is obvious, it is convenient to smear, and action time is short and significant effect, i.e., can play the role of that As the medicine took effect, the symptoms lessened in the short period；Effective ingredient in Moschus, radix saposhnikoviae, Radix Salviae Miltiorrhizae and the root of three-nerved spicebush is adequately extracted by extraction, after mixing with other raw materials, the penetrating power of drug can be remarkably reinforced, and preparation method is simple by the preparation method of rhinitis plaster of the invention, can be with use of large-scale production.
Description
Technical field
The invention belongs to pharmaceutical technology fields, and in particular to a kind of rhinitis plaster and preparation method thereof.
Background technique
Rhinitis and nasal cavity inflammatory disease are noses caused by viral, the various physical and chemical introductions of bacterium and certain systemic diseases
The inflammation of chamber mucous membrane.The main pathological change of rhinitis is bronchia mucosal hyperemia, swelling, exudation, hyperplasia, atrophy or necrosis etc..Nose
Inflammation brings many inconvenience to people's lives, and other symptoms multiplicity will lead to nasal obstruction, rhiocnesmus, sneezing, rhinorrhea, serious person
It results even in its nose and feels forfeiture, dizzy, insomnia, and then lead to memory loss, quality of life degradation.
Treatment for rhinitis, the prior art there is no radical cure method, the method for generally having following several treatments, alleviating,
In one is whole body and the local cause of disease according to etiological treatment, is first found out, treat systemic chronic disease in time, nasosinusitis, close on
Infection focus and deviation of nasal septum etc., then have in mind and make the life better and working environment, it takes exercises, improves Abwehrkraft des Koepers.It is another
Kind is local treatment, using glucocorticoid is intranasally used, is the medication of rhinitis chronic first choice, has good anti-inflammatory effect, and most
Congestion effect is generated eventually.The existing drug for treating rhinitis on the market is generally spray or the Western medicine using some anti-inflammatory drugs, this
It is merely able to play the role of postponement, and Western medicine has drug resistance, if used for a long time, it will lose effect, Western medicine tool
There is side effect, should not also use for a long time.The some plaster also occurred are caused by the disease such as rhinitis, paranasal sinusitis for the treatment of patient
Thin nasal discharge, turbid nasal discharge, sneeze, sleep mouth breathing, tears liquid flow backward into symptoms such as larynx, dizziness, alliteration, headaches, and the course of disease several years
The even rhinitis of decades, paranasal sinusitis patient, lacking has the liniment of obvious clinical efficacy to treat, and has seriously affected patient
Health and work and quality of life.
For these reasons, the present invention is specifically proposed.
Summary of the invention
In order to solve problem above of the existing technology, the present invention provides a kind of rhinitis plaster and preparation method thereof,
Rhinitis plaster Medicated Permeation ability of the invention is strong, and go directly lesions position, and a surname's clearing the nasal passage, relieving cough and asthma, warming yang and benefiting qi effect is bright
Aobvious, it is convenient to smear, and function and effect are significant.
To achieve the goals above, the present invention adopts the following technical scheme:
A kind of rhinitis plaster, including the following raw material are made: Moschus, cortex cinnamomi, the root of Dahurain angelica, pinellia, vinegar rhizoma corydalis, asarum, Qiang
Work, Korean ginseng, radix saposhnikoviae, aconiti preparata,radix, Radix Salviae Miltiorrhizae, radix aucklandiae, the root of three-nerved spicebush and flos caryophylli.
Further, it is made according to parts by weight, including the following raw material: Moschus 5-15 parts by weight, cortex cinnamomi 180-220 weight
Part, root of Dahurain angelica 180-220 parts by weight, pinellia 180-220 parts by weight, vinegar rhizoma corydalis 180-220 parts by weight, asarum 130-170 weight
Measure part, Rhizoma Et Radix Notopterygii 130-170 parts by weight, Korean ginseng 130-170 parts by weight, radix saposhnikoviae 80-120 parts by weight, aconiti preparata,radix 40-60 weight
Part, Radix Salviae Miltiorrhizae 80-120 parts by weight, radix aucklandiae 90-110 parts by weight, root of three-nerved spicebush 180-220 parts by weight and flos caryophylli 180-220 parts by weight.
Further, it is made according to parts by weight, including the following raw material: Moschus 8-12 parts by weight, cortex cinnamomi 190-210 weight
Part, root of Dahurain angelica 195-205 parts by weight, pinellia 195-205 parts by weight, vinegar rhizoma corydalis 195-205 parts by weight, asarum 140-160 weight
Measure part, Rhizoma Et Radix Notopterygii 140-160 parts by weight, Korean ginseng 140-160 parts by weight, radix saposhnikoviae 90-110 parts by weight, aconiti preparata,radix 45-55 weight
Part, Radix Salviae Miltiorrhizae 90-110 parts by weight, radix aucklandiae 95-105 parts by weight, root of three-nerved spicebush 190-210 parts by weight and flos caryophylli 190-210 parts by weight.
Further, it is made according to parts by weight, including the following raw material: 10 parts by weight of Moschus, 200 parts by weight of cortex cinnamomi, the root of Dahurain angelica
200 parts by weight, 200 parts by weight of pinellia, 200 parts by weight of vinegar rhizoma corydalis, 150 parts by weight of asarum, 150 parts by weight of Rhizoma Et Radix Notopterygii, Koryo
Join 150 parts by weight, windproof 100 parts by weight, 50 parts by weight of aconiti preparata,radix, 100 parts by weight of Radix Salviae Miltiorrhizae, 100 parts by weight of radix aucklandiae, the root of three-nerved spicebush 200
200 parts by weight of parts by weight and flos caryophylli.
Moschus, which is called, loses perfume, navel perfume, hearty cord perfume, when the door etc., is point of the glandular sac between the navel and genitals of male musk deer
Secretion is in granular form or blocky after dry, has special fragrance, there is bitter taste, fragrance can be made, can also be used as medicine.For blood
Stasis of blood menostasis levies lump in the abdomen, trusted subordinate sudden and violent pain, traumatic injury, wind-cold-dampness arthralgia, activating microcirculation and removing stasis medicinal etc..
Cortex cinnamomi is using the dry hide of lauraceae plant cortex cinnamomi as medicinal position, and Chinese medicine thinks its warm-natured acrid flavour, sweet, there is complement
The effect of sun, warming spleen and stomach, removing internal cold etc., can be clinically used for the diseases such as cold limbs, abdominal pain diarrhoea or waist and knee crymodynia
The treatment of symptom.
Root of Dahurain angelica wind-damp dispelling, apocenosis of invigorating blood circulation, myogenic pain relieving.For having a headache, having a toothache, nasosinusitis, intestines wind anal fistula, leukorrhea with reddish discharge, carbuncle
Subcutaneous ulcer sore, pruitus.
Pinellia is common Chinese medicinal material, is the Preparation process product of the tuber of pinellia.The tuber of pinellia is with virose a herb material, nature and flavor
Pungent-warm, because its acrid flavour is peppery, numb tongue due to pierce larynx, the irritation with " halberd people pharynx ", one of processed product obtained after processing ginger is partly
Summer toxicity reduces.
The promoting blood circulation of vinegar rhizoma corydalis；Promoting the circulation of qi；Analgesic.For all pain cards of stagnation of QI-blood；It is usually used in chest impediment and cardialgia, stomachache, liver depression gas
The stagnant distending pain in hypochondrium, dysmenorrhea, postpartum stasis abdominal pain, cold hernia stomachache, traumatic injury, rheumatic arthralgia etc..Vinegar rhizoma corydalis: it takes and prolongs only recklessly
Rope is mixed thoroughly with vinegar, infiltration, until vinegar exhausts, sets micro- dry with being fried with slow fire in pot, taking-up cools；Or net rhizoma corydalis is taken, add vinegar to set
It is boiled altogether in pot, until vinegar exhausts, dries, take out, cool.The effect of analgesic can be enhanced after vinegar system.
Asarum is warm-natured, acrid flavour, slightly poisonous, has the effect of cold dispelling wind-dispelling, analgesic, warming lung and resolving fluid, sensible etc., clinical
On can be used for the treatments of the disease symptoms such as exterior syndrome due to wind-cold, rheumatic arthralgia and headache, toothache.
Rhizoma Et Radix Notopterygii is very effective in cure to affection of exogenous wind-cold, and Rhizoma Et Radix Notopterygii has the function of antipyretic analgesic, treats anemofrigid cold, cough due to common cold etc.
Symptom.Have the function of wind-expelling pain-stopping, is mainly used for rheumatic and rheumatoid, arthritis, the diseases such as scapulohumeral periarthritis.
Korean ginseng have reinforce vital energy, strengthening by means of tonics, promote the production of body fluid to quench thirst, intelligence development and other effects of allaying excitement, be suitable for insomnia of palpitating with fear person,
Physically weak person, heart failure, cardiogenic shock etc..
Anti- wind, relieving exterior syndrome is length with wind-dispelling, dispersing wind and cold and can dissipate wind-heat, can wind-damp dispelling and relieve pain, Chang Peihe Rhizoma Et Radix Notopterygii,
Root of fangji etc. treats the diseases such as rheumatic arthralgia.Radix saposhnikoviae controls tetanus, there is expelling wind and relieving convulsion.
Aconiti preparata,radix dispelling wind and eliminating dampness, antalgic are used for treating arthralgia due to cold and dampness, and joint crymodynia, cold hernia is had a pain and narcotic analgesic.
The effect of Radix Salviae Miltiorrhizae has promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness and restlessness, cool blood to disappear carbuncle.For chest impediment and cardialgia, the stomach duct and abdomen side of body
Bitterly, a lump in the abdomen causing distension and pain, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhea menostasis, sore swell and ache curative.
Also there are many crude drug ingredient, its antibacterial with super strength and antiinflammations in radix aucklandiae, can inhibit more in human body
Kind pathogenic bacteria breed and breeding, have very outstanding inhibition and elimination to act on the intracorporal Escherichia coli of people and corynebacterium diphtheriae.
The root of three-nerved spicebush is used for cold obstruction causing qi stagnation, and chest and abdomen swelling and pain, circulation of vital energy in the wrong direction asthma is anxious, deficiency-cold in the urinary bladder, enuresis frequent micturition, hernia pain, through abdomen of trembling with fear
Bitterly.
Flos caryophylli is acrid in flavour and warm in nature.Returns spleen, stomach, lung, kidney channel.Fear Radix Curcumae.Inverse, eliminating cold to stop pain, warming kidney and enhancing yang drop in middle benefit gas.
Moschus, asarum, radix saposhnikoviae, root of Dahurain angelica a surname active row of clearing the nasal passage in the present invention is turbid；Cortex cinnamomi, Korean ginseng, flos caryophylli Wen Yang
QI invigorating；Pinellia, aconiti preparata,radix, radix aucklandiae cold dispelling qi-regulating Zhichuan；Rhizoma Et Radix Notopterygii, Radix Salviae Miltiorrhizae, root of three-nerved spicebush temperature are through stagnation resolvation qi-regulating.
Rhinitis plaster treating rhinitis of the invention, paranasal sinusitis, cough, asthma, bronchitis, stomachache with cool feeling, ephidrosis,
Indigestion, constipation due to deficiency of vital energy, hypoimmunity etc..A surname clearing the nasal passage, warming yang and benefiting qi, it is relieving cough and asthma, help win prevent prolapse.
Application method: it is of different sizes according to painful area, suitable dressing patch is selected, it is appropriate to dip in plaster with spatula,
Even painting is smoothed out on dressing patch, being affixed on affected part, is removed after 24 hours.
A kind of preparation method of the rhinitis plaster, includes the following steps:
(1) it is weighed respectively according to the weight of each raw material spare；
(2) each raw material is crushed respectively it is spare, by smashed Moschus, radix saposhnikoviae, Radix Salviae Miltiorrhizae and the root of three-nerved spicebush addition volume fraction be
It is extracted in 75% alcohol, collects leachate and filter residue；
(3) it is crushed after drying filter residue, leachate is concentrated under reduced pressure into no ethanol flavor, obtains concentrate；
(4) concentrate, the filter residue of crushing and other remaining raw materials are mixed, honey is added, stirs evenly, obtains
The rhinitis plaster.
Further, 80-100 mesh is crushed in step (2).
Further, the Alcohol by weight that volume fraction is 75% in step (2) is weight in Moschus, radix saposhnikoviae, Radix Salviae Miltiorrhizae and the root of three-nerved spicebush
2.5-3.5 times of amount.
Further, 200-300 mesh is crushed in step (3).
Further, the mass ratio of honey and other remaining raw materials is 2-4:1 in step (4).
Further, the mass ratio of honey and other remaining raw materials is 3:1 in step (4).
Other remaining raw materials refer to the raw material except Moschus, radix saposhnikoviae, Radix Salviae Miltiorrhizae and the root of three-nerved spicebush in the present invention.
Compared with prior art, the invention has the benefit that
(1) rhinitis plaster of the invention passes through the synergistic effect of each raw material, has stronger penetrating power, lesion of going directly,
Declare that clearing the nasal passage, relieving cough and asthma, warming yang and benefiting qi effect is obvious, it is convenient to smear, and action time is short and significant effect, i.e., in the short period
It can play the role of that As the medicine took effect, the symptoms lessened；
(2) raw material of the invention is all made of natural material and is prepared, for treating rhinitis, paranasal sinusitis, cough, heavy breathing
Asthma, bronchitis, stomachache with cool feeling, ephidrosis, indigestion, constipation due to deficiency of vital energy, hypoimmunity etc. have good effect, do not have
The problems such as side effect is not easy allergy, and the position of application is not in redness；
(3) preparation method of rhinitis plaster of the invention, will be effective in Moschus, radix saposhnikoviae, Radix Salviae Miltiorrhizae and the root of three-nerved spicebush by extraction
Composition adequately extracts, and after mixing with other raw materials, the penetrating power of drug can be remarkably reinforced, and preparation method is simple, can
With use of large-scale production.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical solution of the present invention will be carried out below
Detailed description.Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art are obtained all without making creative work
Other embodiment belongs to the range that the present invention is protected.
Embodiment 1
A kind of rhinitis plaster of the present embodiment, including the following raw material are made: Moschus 5g, cortex cinnamomi 180g, root of Dahurain angelica 180g, ginger half
Summer 180g, vinegar rhizoma corydalis 180g, asarum 130g, Rhizoma Et Radix Notopterygii 130g, Korean ginseng 130g, radix saposhnikoviae 80g, aconiti preparata,radix 40g, Radix Salviae Miltiorrhizae 80g, wood
Fragrant 90g, root of three-nerved spicebush 180g and flos caryophylli 180g.
The preparation method of the rhinitis plaster of the present embodiment, includes the following steps:
(1) it is weighed respectively according to the weight of each raw material spare；
(2) that each raw material is crushed to 80-100 mesh respectively is spare, and smashed Moschus, radix saposhnikoviae, Radix Salviae Miltiorrhizae and the root of three-nerved spicebush are added
It is extracted in the alcohol that volume fraction is 75%, Alcohol by weight is Moschus, radix saposhnikoviae, 2.5 times of weight in Radix Salviae Miltiorrhizae and the root of three-nerved spicebush, is received
Collect leachate and filter residue；
(3) it carries out being crushed to 200-300 mesh after drying filter residue, leachate is concentrated under reduced pressure into no ethanol flavor, is obtained
To concentrate；
(4) concentrate, the filter residue of crushing and other remaining raw materials are mixed, be added honey, honey with it is remaining
The mass ratio of other raw materials is 2:1, is stirred evenly, and the rhinitis plaster is obtained.
Embodiment 2
A kind of rhinitis plaster of the present embodiment, including the following raw material are made: Moschus 8g, cortex cinnamomi 190g, root of Dahurain angelica 195g, ginger half
Summer 195g, vinegar rhizoma corydalis 195g, asarum 140g, Rhizoma Et Radix Notopterygii 140g, Korean ginseng 140g, radix saposhnikoviae 90g, aconiti preparata,radix 45g, Radix Salviae Miltiorrhizae 90g, wood
Fragrant 95g, root of three-nerved spicebush 190g and flos caryophylli 190g.
The preparation method of the rhinitis plaster of the present embodiment, includes the following steps:
(1) it is weighed respectively according to the weight of each raw material spare；
(2) that each raw material is crushed to 80-100 mesh respectively is spare, and smashed Moschus, radix saposhnikoviae, Radix Salviae Miltiorrhizae and the root of three-nerved spicebush are added
It is extracted in the alcohol that volume fraction is 75%, Alcohol by weight is Moschus, radix saposhnikoviae, 3 times of weight in Radix Salviae Miltiorrhizae and the root of three-nerved spicebush, is collected
Leachate and filter residue；
(3) it carries out being crushed to 200-300 mesh after drying filter residue, leachate is concentrated under reduced pressure into no ethanol flavor, is obtained
To concentrate；
(4) concentrate, the filter residue of crushing and other remaining raw materials are mixed, be added honey, honey with it is remaining
The mass ratio of other raw materials is 3:1, is stirred evenly, and the rhinitis plaster is obtained.
Embodiment 3
A kind of rhinitis plaster of the present embodiment, including the following raw material are made: Moschus 10g, cortex cinnamomi 200g, root of Dahurain angelica 200g, ginger
Tuber of pinellia 200g, vinegar rhizoma corydalis 200g, asarum 150g, Rhizoma Et Radix Notopterygii 150g, Korean ginseng 150g, radix saposhnikoviae 100g, aconiti preparata,radix 50g, Radix Salviae Miltiorrhizae
100g, radix aucklandiae 100g, root of three-nerved spicebush 200g and flos caryophylli 200g.
The preparation method of the rhinitis plaster of the present embodiment, includes the following steps:
(1) it is weighed respectively according to the weight of each raw material spare；
(2) that each raw material is crushed to 80-100 mesh respectively is spare, and smashed Moschus, radix saposhnikoviae, Radix Salviae Miltiorrhizae and the root of three-nerved spicebush are added
It is extracted in the alcohol that volume fraction is 75%, Alcohol by weight is Moschus, radix saposhnikoviae, 3 times of weight in Radix Salviae Miltiorrhizae and the root of three-nerved spicebush, is collected
Leachate and filter residue；
(3) it carries out being crushed to 200-300 mesh after drying filter residue, leachate is concentrated under reduced pressure into no ethanol flavor, is obtained
To concentrate；
(4) concentrate, the filter residue of crushing and other remaining raw materials are mixed, be added honey, honey with it is remaining
The mass ratio of other raw materials is 3:1, is stirred evenly, and the rhinitis plaster is obtained.
Embodiment 4
A kind of rhinitis plaster of the present embodiment, including the following raw material are made: Moschus 12g, cortex cinnamomi 210g, root of Dahurain angelica 205g, ginger
Tuber of pinellia 205g, vinegar rhizoma corydalis 205g, asarum 160g, Rhizoma Et Radix Notopterygii 160g, Korean ginseng 160g, radix saposhnikoviae 110g, aconiti preparata,radix 55g, Radix Salviae Miltiorrhizae
110g, radix aucklandiae 105g, root of three-nerved spicebush 210g and flos caryophylli 210g.
The preparation method of the rhinitis plaster of the present embodiment, includes the following steps:
(1) it is weighed respectively according to the weight of each raw material spare；
(2) that each raw material is crushed to 80-100 mesh respectively is spare, and smashed Moschus, radix saposhnikoviae, Radix Salviae Miltiorrhizae and the root of three-nerved spicebush are added
It is extracted in the alcohol that volume fraction is 75%, Alcohol by weight is Moschus, radix saposhnikoviae, 2.8 times of weight in Radix Salviae Miltiorrhizae and the root of three-nerved spicebush, is received
Collect leachate and filter residue；
(3) it carries out being crushed to 200-300 mesh after drying filter residue, leachate is concentrated under reduced pressure into no ethanol flavor, is obtained
To concentrate；
(4) concentrate, the filter residue of crushing and other remaining raw materials are mixed, be added honey, honey with it is remaining
The mass ratio of other raw materials is 3.5:1, is stirred evenly, and the rhinitis plaster is obtained.
Embodiment 5
A kind of rhinitis plaster of the present embodiment, including the following raw material are made: Moschus 15g, cortex cinnamomi 220g, root of Dahurain angelica 220g, ginger
Tuber of pinellia 220g, vinegar rhizoma corydalis 220g, asarum 170g, Rhizoma Et Radix Notopterygii 170g, Korean ginseng 170g, radix saposhnikoviae 120g, aconiti preparata,radix 60g, Radix Salviae Miltiorrhizae
120g, radix aucklandiae 110g, root of three-nerved spicebush 220g and flos caryophylli 220g.
The preparation method of the rhinitis plaster of the present embodiment, includes the following steps:
(1) it is weighed respectively according to the weight of each raw material spare；
(2) that each raw material is crushed to 80-100 mesh respectively is spare, and smashed Moschus, radix saposhnikoviae, Radix Salviae Miltiorrhizae and the root of three-nerved spicebush are added
It is extracted in the alcohol that volume fraction is 75%, Alcohol by weight is Moschus, radix saposhnikoviae, 3.5 times of weight in Radix Salviae Miltiorrhizae and the root of three-nerved spicebush, is received
Collect leachate and filter residue；
(3) it carries out being crushed to 200-300 mesh after drying filter residue, leachate is concentrated under reduced pressure into no ethanol flavor, is obtained
To concentrate；
(4) concentrate, the filter residue of crushing and other remaining raw materials are mixed, be added honey, honey with it is remaining
The mass ratio of other raw materials is 4:1, is stirred evenly, and the rhinitis plaster is obtained.
Comparative example 1
The raw material and preparation method and embodiment 3 of the rhinitis plaster of this comparative example preparation are all the same, the difference is that, musk deer
Fragrant, radix saposhnikoviae, Radix Salviae Miltiorrhizae and the root of three-nerved spicebush are handled without extraction, directly mix each raw material.
Test example pharmacodynamics test
1, experimental animal
Healthy female cavy 70 are chosen, 240-260g/ only, is provided by Fujian University of Traditional Chinese Medicine's Experimental Animal Center.Nose
Scorching model mice modeling mode (the Nasal hypersensitivity experimental model such as Zhao Xiuwen establish [J] China hals,Nasen und Ohrenheilkunde magazine,
1993) 7 groups, every group 10, are randomly divided into.
Modeling cavy is killed at the 30th day, it is sterile to take spleen and shred, splenic lymphocytes are separated with density-gradient centrifugation method,
It is placed on 5%CO2, is cultivated in 37 DEG C of incubators.The plaster 10g that 1-5 group is prepared to embodiment 1-5 respectively, the 6th group to comparative example
The plaster 10g of 1 preparation, the 7th group is not administered as blank control group, culture for 24 hours, 48h and 72 hour, existed with microplate reader measurement
OD value at 450mm, measurement drug is to spleen lymphocyte proliferation inhibiting rate, and (1- administration group OD/ is empty by proliferation inhibition rate R=
White control group OD) × 100%, it the results are shown in Table 1.
Table 1
The emplastrum of embodiment 1-5 preparation makees spleen lymphocyte proliferation with a degree of inhibition as can be seen from the above table
With, and it is higher than the inhibiting rate of the emplastrum of the preparation of comparative example 1, illustrate that rhinitis models mouse can be effectively relieved in emplastrum of the invention
Inflammation has certain therapeutic effect to rhinitis illness, and therapeutic effect of the invention is good.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of rhinitis plaster, which is characterized in that be made including the following raw material: Moschus, cortex cinnamomi, the root of Dahurain angelica, pinellia, vinegar prolong recklessly
Rope, asarum, Rhizoma Et Radix Notopterygii, Korean ginseng, radix saposhnikoviae, aconiti preparata,radix, Radix Salviae Miltiorrhizae, radix aucklandiae, the root of three-nerved spicebush and flos caryophylli.
2. rhinitis plaster according to claim 1, which is characterized in that be made according to parts by weight, including the following raw material: Moschus
5-15 parts by weight, cortex cinnamomi 180-220 parts by weight, root of Dahurain angelica 180-220 parts by weight, pinellia 180-220 parts by weight, vinegar rhizoma corydalis
180-220 parts by weight, asarum 130-170 parts by weight, Rhizoma Et Radix Notopterygii 130-170 parts by weight, Korean ginseng 130-170 parts by weight, radix saposhnikoviae 80-
120 parts by weight, aconiti preparata,radix 40-60 parts by weight, Radix Salviae Miltiorrhizae 80-120 parts by weight, radix aucklandiae 90-110 parts by weight, root of three-nerved spicebush 180-220 weight
Part and flos caryophylli 180-220 parts by weight.
3. rhinitis plaster according to claim 2, which is characterized in that be made according to parts by weight, including the following raw material: Moschus
8-12 parts by weight, cortex cinnamomi 190-210 parts by weight, root of Dahurain angelica 195-205 parts by weight, pinellia 195-205 parts by weight, vinegar rhizoma corydalis
195-205 parts by weight, asarum 140-160 parts by weight, Rhizoma Et Radix Notopterygii 140-160 parts by weight, Korean ginseng 140-160 parts by weight, radix saposhnikoviae 90-
110 parts by weight, aconiti preparata,radix 45-55 parts by weight, Radix Salviae Miltiorrhizae 90-110 parts by weight, radix aucklandiae 95-105 parts by weight, root of three-nerved spicebush 190-210 weight
Part and flos caryophylli 190-210 parts by weight.
4. rhinitis plaster according to claim 3, which is characterized in that be made according to parts by weight, including the following raw material: Moschus
10 parts by weight, 200 parts by weight of cortex cinnamomi, 200 parts by weight of the root of Dahurain angelica, 200 parts by weight of pinellia, 200 parts by weight of vinegar rhizoma corydalis, asarum
150 parts by weight, 150 parts by weight of Rhizoma Et Radix Notopterygii, 150 parts by weight of Korean ginseng, windproof 100 parts by weight, 50 parts by weight of aconiti preparata,radix, Radix Salviae Miltiorrhizae 100
Parts by weight, 200 parts by weight of 100 parts by weight of radix aucklandiae, 200 parts by weight of the root of three-nerved spicebush and flos caryophylli.
5. a kind of preparation method of rhinitis plaster described in claim 1-4 any one, which is characterized in that including walking as follows
It is rapid:
(1) it is weighed respectively according to the weight of each raw material spare；
(2) each raw material is crushed respectively it is spare, by smashed Moschus, radix saposhnikoviae, Radix Salviae Miltiorrhizae and the root of three-nerved spicebush be added volume fraction be 75%
Alcohol in extracted, collect leachate and filter residue；
(3) it is crushed after drying filter residue, leachate is concentrated under reduced pressure into no ethanol flavor, obtains concentrate；
(4) concentrate, the filter residue of crushing and other remaining raw materials are mixed, honey is added, stirs evenly, obtained described
Rhinitis plaster.
6. the preparation method of rhinitis plaster according to claim 5, which is characterized in that step is crushed to 80-100 in (2)
Mesh.
7. the preparation method of rhinitis plaster according to claim 5, which is characterized in that volume fraction is in step (2)
75% Alcohol by weight is Moschus, radix saposhnikoviae, 2.5-3.5 times of weight in Radix Salviae Miltiorrhizae and the root of three-nerved spicebush.
8. the preparation method of rhinitis plaster according to claim 5, which is characterized in that step is crushed to 200-300 in (3)
Mesh.
9. the preparation method of rhinitis plaster according to claim 5, which is characterized in that in step (4) honey with it is remaining
The mass ratio of other raw materials is 2-4:1.
10. the preparation method of rhinitis plaster according to claim 9, which is characterized in that in step (4) honey with it is remaining
The mass ratio of other raw materials is 3:1.
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| CN103099848A (en) * | 2012-12-13 | 2013-05-15 | 新昌县冠阳技术开发有限公司 | Nasal obstruction for treating anaphylactic rhinitis |
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Application publication date: 20190621 |