CN103110749B - Traditional Chinese medicine composition for treating chloasma - Google Patents
Traditional Chinese medicine composition for treating chloasma Download PDFInfo
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- CN103110749B CN103110749B CN201310069298.7A CN201310069298A CN103110749B CN 103110749 B CN103110749 B CN 103110749B CN 201310069298 A CN201310069298 A CN 201310069298A CN 103110749 B CN103110749 B CN 103110749B
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Abstract
The invention discloses a traditional Chinese medicine composition for treating chloasma. The traditional Chinese medicine composition is prepared from oriental bittersweet roots, wilson passion flowers, achyranthes aspera, field melasma herbs, folium isatidis, siberian walking fern, Japanese ardisia herbs, oroxylum indicum, radix paeoniae alba, cow pea pod, medical stones and cornu bubali. The traditional Chinese medicine composition can be used for treating chloasma clinically.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of chloasma.
Background technology
Chloasma is a kind of chromatopathy that betides face, skin lesion is filbert to dark brown, well-defined patch, often be symmetrically distributed in face, NIP performance and squama, without obvious subjective symptoms, women is multiple, mainly occurs in after adolescence, the state of an illness can have seasonality, and the Chang Xiachong winter is light.Though it is attractive in appearance that patient, without significant discomfort, hinders, patients ' psychological is posed a big pressure, severe patient can affect work and life.Through inventor's long-term practice, draw, the Chinese medicine brown patch of harnessing the Yellow River has better effect, obtains good effect.
Summary of the invention
The object of the present invention is to provide the Chinese medicine composition of the treatment chloasma that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Radix Celastri Orbiculati, Herba Passiflorae Wilsonii, Radix Achyranthis, Herba Melasmatis arvensis, Folium Isatidis, Herba Camptosori Sibirici, Herba Ardisiae Japonicae, Semen Oroxyli, the Radix Paeoniae Alba, Pericarpium Vignae sinensis, Maifanitum, Cornu Bubali are according to certain compatibility requirement, through being processed into.
Preparing Chinese medicine composition of the present invention is made by following raw material medicaments: Radix Celastri Orbiculati 40-60 part, Herba Passiflorae Wilsonii 30-50 part, Radix Achyranthis 30-50 part, Herba Melasmatis arvensis 30-50 part, Folium Isatidis 20-40 part, Herba Camptosori Sibirici 20-40 part, Herba Ardisiae Japonicae 20-40 part, Semen Oroxyli 10-25 part, Radix Paeoniae Alba 10-25 part, Pericarpium Vignae sinensis 10-25 part, Maifanitum 8-15 part, Cornu Bubali 6-10 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 50 parts of Radix Celastri Orbiculatis, 40 parts of Herba Passiflorae Wilsoniis, 40 parts of Radix Achyranthis, 40 parts of Herba Melasmatis arvensiss, 30 parts of Folium Isatidiss, 30 parts of Herba Camptosori Sibiricis, 30 parts of Herba Ardisiae Japonicaes, 20 parts of Semen Oroxylis, 18 parts of the Radix Paeoniae Albas, 20 parts of Pericarpium Vignae sinensiss, 12 parts of Maifanitums, 8 parts of Cornu Bubalis.
The pharmacological action of Chinese medicine of the present invention is as follows:
Radix Celastri Orbiculati: pungent, bitter, flat.Return kidney, bladder, Liver Channel.Expelling wind and removing dampness, promoting blood circulation to restore menstrual flow, subduing swelling and detoxicating.Clinical in rheumatic arthralgia, treating swelling and pain by traumatic injury, amenorrhea, headache, lumbago, hernia pain, the diseases such as dysentery carbuncle pyogenic infections from tumour or sore.
Herba Passiflorae Wilsonii: bitter, warm.Wind-damp dispelling, invigorating the liver and kidney, promoting blood flow to regulate menstruation, parasite killing preventing the attack (or recurrence) of malaria.For rheumatic ostalgia, sore waist and aching in the waist and the back, hepatitis, liver cirrhosis, menoxenia, traumatic injury, fracture, the diseases such as malaria.
Radix Achyranthis: sweet, micro-hardship, micro-acid, cold in nature.Return liver, kidney channel.Blood circulation promoting and blood stasis dispelling, eliminating fire and detoxication, inducing diuresis for treating stranguria syndrome.For amenorrhea, traumatic injury, Fengshi Guanjie pain, dysentery, diphtheria, laryngopharynx swelling and pain, the diseases such as edema.
Herba Melasmatis arvensis: micro-hardship, cool.Clearing away heat-damp and promoting diuresis, promoting blood circulation to remove blood stasis.For icterohepatitis, traumatic injury, the diseases such as dysmenorrhea.
Folium Isatidis: bitter, cold.Return liver, the heart, stomach, spleen channel.Heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.For the high hot excessive thirst of calentura, coma, macule, spits blood, epistaxis, jaundice, dysentery etc.
Herba Camptosori Sibirici: light, flat.GUIXIN warp.Blood circulation promoting and blood stasis dispelling, hemostasis, removing toxic substances.For thromboangiitis obliterans, hemiplegia, metrorrhagia, traumatic hemorrhage, neurodermatitis, ulcer of the lower limb.
Herba Ardisiae Japonicae: pungent, micro-hardship, flat.Return lung, Liver Channel.Preventing phlegm from forming and stopping coughing, dampness removing, invigorates blood circulation.For new chronic cough, cough, sputum mixed with blood, jaundice, edema, stranguria, leucorrhea, amenorrhea dysmenorrhea, rheumatic arthralgia, traumatic injury, the diseases such as painful and swollen testis.
Semen Oroxyli: micro-hardship, sweet, be slightly cold.Return lung, liver, stomach warp.Sore-throat relieving lung moistening, dispersing the stagnated liver-QI for regulating the stomach, expelling pus and promoting granulation.For pharyngalgia sore throat, hoarseness, cough, stomachache due to hyperactive liver-QI attacking the stomach, skin infection is burst for a long time and is not more waited disease.
The Radix Paeoniae Alba: bitter, sour, be slightly cold, return liver, spleen channel.Nourish blood and seek, relieving spasm to stop pain, yin fluid astringing suppressing the hyperactive liver.Cure mainly blood deficiency cold and heat, epigastric pain, has a headache dizzy.
Pericarpium Vignae sinensis: sweet, flat.Return stomach warp.Kidney and spleen invigorating, inducing diuresis to remove edema, analgesia, removing toxic substances.For lumbago, nephritis, cholecystitis, herpes zoster, the diseases such as acute mastitis.
Maifanitum: sweet, warm.Return liver, stomach, kidney channel.Detoxicating and resolving stagnation of pathogens, removing the necrotic tissue and promoting granulation, except cold damp eliminating, the liver benefiting stomach invigorating, blood circulation promoting and blood stasis dispelling, diuresis fossil.Clinical in carbuncle, acne, eczema, beriberi, miliaria, finger is chapped, chloasma, toothache, oral ulcer, rheumatic arthralgia, chronic hepatitis, gastritis, dysentery, neurasthenia, wound is red and swollen, hypertension, senile sclerosis of blood vessels, the diseases such as lithangiuria.
Cornu Bubali: bitter, salty, cold.GUIXIN, Liver Channel.Heat clearing away, removing toxic substances, removing heat from blood, arresting convulsion.For calentura headache, the hot coma of business, sends out speckle dermexanthesis, stagnant heat jaundice, infantile convulsion and laryngopharynx swelling and pain, aphtha of the mouth and tongue etc.
Chloasma belongs to the category of Chinese medicine " chloasma ", mainly by suffer from a deficiency of the kidney and blood paralysis due to.Suffering from a deficiency of the kidney is the basic of morbidity, and blood addiction is mark, has a close relationship with liver,spleen,kidney three is dirty.Angry owing to being worried, cause liver and lose bar and reach, so that stagnation of QI blood stain, the sick positive QI-insufficiency of patient for a long time, imbalance of YIN and YANG, the consume of Liver and kidney essence and blood punching appoint in debt, QI and blood must not on hold, face network loses in making moist, the true qualities of kidney are revealed in face, there is chloasma in face.Radix Celastri Orbiculati promoting blood circulation to restore menstrual flow in the present invention, the removing toxic substances of dispeling the wind, is monarch drug, Herba Passiflorae Wilsonii promoting blood flow to regulate menstruation, invigorating the liver and kidney, Radix Achyranthis blood circulation promoting and blood stasis dispelling, Herba Melasmatis arvensis clearing away heat-damp and promoting diuresis, promoting blood circulation to remove blood stasis, is ministerial drug, Folium Isatidis blood cooling and ecchymoses removing, Herba Camptosori Sibirici, Herba Ardisiae Japonicae blood circulation promoting and blood stasis dispelling, Semen Oroxyli expelling pus and promoting granulation, the Radix Paeoniae Alba joint venture of nourishing blood, Pericarpium Vignae sinensis kidney and spleen invigorating, removing toxic substances, the stomach invigorating of Maifanitum the liver benefiting, blood circulation promoting and blood stasis dispelling, Cornu Bubali removing pathogenic heat from blood and toxic substance from the body.All medicines share plays liver and kidney tonifying altogether, cooling blood and removing stasis, and the effect of the speckle removing of invigorating blood circulation, the removing toxic substances of dispeling the wind, finds that through clinical practice chloasma is had to unique curative effect.
Chinese medicine composition of the present invention was in 2004 to 2010 the routine patients of clinical observation chloasma 55, and clinical report is as follows:
1, physical data
In 55 routine patients, in age 25-63 year, 43 years old mean age was all women.
2, diagnostic criteria
The < < traditional Chinese medical science disease Standardization of diagnosis and curative effect > > that diagnosis basis State Administration of Traditional Chinese Medicine issues:
Face is filbert to dark brown, well-defined patch, and symmetry distributes conventionally, NIP performance and squama; Without obvious subjective symptoms; Women is multiple, mainly occurs in after adolescence; The state of an illness can have seasonality, and the Chang Xiachong winter is light.
3, exclusion standard
Gestation or women breast-feeding their children; Be associated with liver, cardiovascular disease person; Malignant tumor patient; In 4 weeks, once systematic treating was crossed patient; During treatment, end treatment or change medicine, method person; Cannot judge curative effect or the data judgement person that entirely do not affect the treatment.
4, Therapeutic Method
4.1 prescriptions: Radix Celastri Orbiculati 50g, Herba Passiflorae Wilsonii 40g, Radix Achyranthis 40g, Herba Melasmatis arvensis 40g, Folium Isatidis 30g, Herba Camptosori Sibirici 30g, Herba Ardisiae Japonicae 30g, Semen Oroxyli 20g, Radix Paeoniae Alba 18g, Pericarpium Vignae sinensis 20g, Maifanitum 12g, Cornu Bubali 8g.
4.2 methods of preparation and use: said medicine routinely technique is made decoction, every day 2 times, 21 days were 1 course for the treatment of at 1 dose of every day.During treatment, note sun-proofly, avoid and take contraceptive, do not abuse cosmetics, avoid psychentonia.
5, therapeutic outcome:
5.1 formulate with reference to < < Chinese medicine Clinical Researches of New Drugs guideline > >:
Cure: naked eyes are depending on the mottle area > 90% that disappears, and color disappears substantially; Point system is calculated, decline index >=0.8 after treatment.
Effective: naked eyes are depending on the mottle area > 60% that disappears, and color is obviously thin out; Point system is calculated, decline index >=0.5 after treatment.
Take a turn for the better: naked eyes are depending on the mottle area > 30% that disappears, and color is thin out; Point system is calculated, decline index >=0.3 after treatment.
Invalid: naked eyes are depending on the mottle area < 30% that disappears, and change color is not obvious; Point system is calculated, and after treatment, decline index becomes≤0.
5.2 methods of marking and standard
Skin lesion area scoring: 0 is without skin lesion; 1 is area < 2cm
2time; 2 is area 2cm
2-4cm
2time; 3 is skin lesion area > 4cm
2time.Skin lesion color scoring: 0 is the normal colour of skin; 1 is filbert; 2 is brown; 3 is dark brown.
The scoring of total mark=area scoring+color.
Point system decline index calculation method: total mark before decline index=(the rear total mark of total mark-treatment before treatment)/treatment.
5.3 results: in 55 routine patients, clinical cure 21 examples (38.2%), effective 19 examples (34.5%), 9 examples (16.3%) that take a turn for the better, invalid 6 examples (11%), total effective rate is 89%.
6, model case
6.1 weeks certain, female, 36 years old, there is chloasma in face, color is deepened gradually, spreads all over volume, cheek, nose, mouthful week etc., is a lamellar, symmetry occurs, without squama, without gargalesthesia, dimly red tongue, has petechia, white and thin fur, stringy and hesitant pulse.Be diagnosed as chloasma.Take medicine of the present invention, treat 1 course for the treatment of, symptom obviously alleviates, and facial black speck part goes down, and continues to take 2 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after half a year without recurrence.
6.2 Chens, female, 35 years old, while cherishing second fetus before 3 years there is chloasma in face, and increase the weight of year by year, upper to 1cm on geisoma line, along the line down to the corners of the mouth, on inside cord, point arises from eyebrow, and mid point is in bridge of the nose outside, and on out conductor, point is at temple, along cheekbone outside, area of chloasma accounts for 2/3 of whole face, presents dark brown a slice, symmetry.Be diagnosed as chloasma.Take medicine of the present invention, 1 dose of every day, after 1 course for the treatment of, chloasma starts to dissipate, and scope is dwindled, and continues to take 2 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
6.3 Liu, female, 45 years old, face played speckle, and companion's poor appetite is sleepy weak, sleeps night and feels unwell, half congealed during stool.Preceeded menorrhea, many, the color of amount secretly have clot, and light red tongue is tender indentation, yellow fur, moderate pulse.Existing buccal, the visible map shape of two cheekbone yellowish-brown patch.Be diagnosed as chloasma.Take medicine of the present invention, 1 dose of every day, after 1 course for the treatment of, brown patch color is thin out, sleep slightly good, and tired alleviating, menstrual blood loss is front minimizing, light red tongue, tongue is white, moderate pulse.Continue to take 2 courses for the treatment of, recovery from illness, continues to take 1 course for the treatment of and consolidates, and follows up a case by regular visits to without recurrence after 1 year
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.
Embodiment 1, a kind of Chinese medicine composition for the treatment of chloasma, be by Radix Celastri Orbiculati 40g, Herba Passiflorae Wilsonii 30g, Radix Achyranthis 30g, Herba Melasmatis arvensis 30g, Folium Isatidis 20g, Herba Camptosori Sibirici 20g, Herba Ardisiae Japonicae 20g, Semen Oroxyli 10g, Radix Paeoniae Alba 10g, Pericarpium Vignae sinensis 10g, Maifanitum 8g, Cornu Bubali 6g make.
Embodiment 2, a kind of Chinese medicine composition for the treatment of chloasma, be by Radix Celastri Orbiculati 50g, Herba Passiflorae Wilsonii 40g, Radix Achyranthis 40g, Herba Melasmatis arvensis 40g, Folium Isatidis 30g, Herba Camptosori Sibirici 30g, Herba Ardisiae Japonicae 30g, Semen Oroxyli 20g, Radix Paeoniae Alba 18g, Pericarpium Vignae sinensis 20g, Maifanitum 12g, Cornu Bubali 8g make.
Embodiment 3, a kind of Chinese medicine composition for the treatment of chloasma, be by Radix Celastri Orbiculati 60g, Herba Passiflorae Wilsonii 50g, Radix Achyranthis 50g, Herba Melasmatis arvensis 50g, Folium Isatidis 40g, Herba Camptosori Sibirici 40g, Herba Ardisiae Japonicae 40g, Semen Oroxyli 25g, Radix Paeoniae Alba 25g, Pericarpium Vignae sinensis 25g, Maifanitum 15g, Cornu Bubali 10g make.
Claims (2)
1. treat a Chinese medicine composition for chloasma, it is characterized in that it is to be made by following raw material medicaments:
Radix Celastri Orbiculati 40-60 part, Herba Passiflorae Wilsonii 30-50 part, Radix Achyranthis 30-50 part, Herba Melasmatis arvensis 30-50 part,
Folium Isatidis 20-40 part, Herba Camptosori Sibirici 20-40 part, Herba Ardisiae Japonicae 20-40 part, Semen Oroxyli 10-25 part,
Radix Paeoniae Alba 10-25 part, Pericarpium Vignae sinensis 10-25 part, Maifanitum 8-15 part, Cornu Bubali 6-10 part.
2. Chinese medicine composition according to claim 1, is characterized in that it is to be made by following raw material medicaments:
50 parts of Radix Celastri Orbiculatis, 40 parts of Herba Passiflorae Wilsoniis, 40 parts of Radix Achyranthis, 40 parts of Herba Melasmatis arvensiss,
30 parts of Folium Isatidiss, 30 parts of Herba Camptosori Sibiricis, 30 parts of Herba Ardisiae Japonicaes, 20 parts of Semen Oroxylis,
18 parts of the Radix Paeoniae Albas, 20 parts of Pericarpium Vignae sinensiss, 12 parts of Maifanitums, 8 parts of Cornu Bubalis.
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| CN1092998A (en) * | 1993-12-29 | 1994-10-05 | 陈能根 | Speckle disappears and preparation method thereof |
| CN1348779A (en) * | 2000-10-17 | 2002-05-15 | 刘宏龙 | Chloasma eliminating medicine |
| CN1403110A (en) * | 2001-09-13 | 2003-03-19 | 余灿明 | Crape myrtle-hibiscus pellet |
| CN1583028A (en) * | 2004-05-31 | 2005-02-23 | 韦益 | Preoparation and production of Taiwan lectuce for catharsis and face nourishment |
| CN101732683A (en) * | 2009-12-25 | 2010-06-16 | 卢速江 | Chinese medicinal preparation for treating facial chloasma and preparation method thereof |
| CN102293893A (en) * | 2010-06-25 | 2011-12-28 | 陈卫兵 | Chinese medicinal cream for whitening skin and removing speckles |
-
2013
- 2013-03-06 CN CN201310069298.7A patent/CN103110749B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1091963A (en) * | 1993-03-08 | 1994-09-14 | 董冬海 | Freckle-removing beauty drug |
| CN1092998A (en) * | 1993-12-29 | 1994-10-05 | 陈能根 | Speckle disappears and preparation method thereof |
| CN1348779A (en) * | 2000-10-17 | 2002-05-15 | 刘宏龙 | Chloasma eliminating medicine |
| CN1403110A (en) * | 2001-09-13 | 2003-03-19 | 余灿明 | Crape myrtle-hibiscus pellet |
| CN1583028A (en) * | 2004-05-31 | 2005-02-23 | 韦益 | Preoparation and production of Taiwan lectuce for catharsis and face nourishment |
| CN101732683A (en) * | 2009-12-25 | 2010-06-16 | 卢速江 | Chinese medicinal preparation for treating facial chloasma and preparation method thereof |
| CN102293893A (en) * | 2010-06-25 | 2011-12-28 | 陈卫兵 | Chinese medicinal cream for whitening skin and removing speckles |
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