CN104013818A - Plaster for treating cancer pains - Google Patents
Plaster for treating cancer pains Download PDFInfo
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- CN104013818A CN104013818A CN201410287521.XA CN201410287521A CN104013818A CN 104013818 A CN104013818 A CN 104013818A CN 201410287521 A CN201410287521 A CN 201410287521A CN 104013818 A CN104013818 A CN 104013818A
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Abstract
The invention relates to a plaster for treating cancer pains, and can effectively solve the problem that cancer pains are difficult to relieve. The plaster is characterized by comprising the following raw medicinal materials by weight: 5-7g of raw monkshood, 5-7g of radix aconiti agrestis, 13-17g of radix angelicae sinensis, 9-11g of corium bufonis, 1.5-2.5g of croton, 27-33g of gamboge, 1.5-2.5g of raw nux vomica, 9-11g of anemonis raddeanae, 5-7g of bletilla striata, 14-16g of rheum officinale, 9-11g of carbonized hair, 9-11g of fructus forsythiae, 14-16g of apiary, 14-16g of radix ampelopsis, 14-16g of caltrop, 14-16g of semen momordicae, 11-13g of pangolin sheet, 11-13g of frankincense, 11-13g of myrrh and 5-7g of dragon blood. The plaster is reasonable in compatibility, is easy to produce and paste, can be applied to a painful part when being used to effectively treat pains caused by various cancers, such as liver cancer, lung cancer, pancreatic cancer, breast cancer, ovarian cancer, bladder cancer, prostatic cancer, colorectal cancer and the like, has the advantages of stability and reliability, good curative effect, quick response, long acting duration, no toxic or side effect, simple, safe and reliable, and is convenient to use.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly a kind of plaster for the treatment of cancerous pain.
Background technology
Cancerous pain generally refers to the pain directly being caused by tumor, as tumor invading or pressuring neural root, nerve trunk, plexus nervorum or nerve, brain, spinal cord, periosteum, skeleton, parenchymal viscera and cavity internal organs etc.Cancerous pain may come across the tumor patient of each phase, and has had a strong impact on patient's quality of life and life span, becomes a great problem of oncology.
Summary of the invention
For above-mentioned situation, for solving the defect of prior art, the present invention's object is just to provide a kind of plaster for the treatment of cancerous pain, can effectively solve the problem that treatment cancerous pain is difficult to effectively be eased.
The technical scheme that the present invention solves is: a kind of plaster for the treatment of cancerous pain, and this plaster comprises crude drug by weight: Radix Aconiti 5-7g, Radix Aconiti Kusnezoffii 5-7g, Radix Angelicae Sinensis 13-17g, dry maxima skin 9-11g, Fructus Crotonis 1.5-2.5g, Resina garciniae 27-33g, Semen Strychni 1.5-2.5g, Rhizoma Anemones Raddeanae 9-11g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-7g, Radix Et Rhizoma Rhei 14-16g, Crinis Carbonisatus 9-11g, Fructus Forsythiae 9-11g, Nidus Vespae 14-16g, Radix Ampelopsis 14-16g, Fructus Tribuli 14-16g, Semen Momordicae 14-16g, Squama Manis sheet 11-13g, Olibanum 11-13g, Myrrha 11-13g and Sanguis Draxonis 5-7g, wherein, by Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Angelicae Sinensis, dry maxima skin, Fructus Crotonis, Resina garciniae, Semen Strychni, Rhizoma Anemones Raddeanae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Crinis Carbonisatus, Fructus Forsythiae, Nidus Vespae, Radix Ampelopsis, Fructus Tribuli, Semen Momordicae and Squama Manis sheet mix to obtain hybrid medicine, add the Oleum sesami identical with hybrid medicine weight, fried after immersion 2h, until the white medicine in hybrid medicine is (as Radix Aconiti, Fructus Crotonis, the Pseudobulbus Bletillae (Rhizoma Bletillae)s etc.) explode into micro-Huang, elimination medicinal residues, obtain medicine fluid, and heating is refined oil to dripping into pearl, then presses medicine fluid, hydrargyrum oxydatum crudum weight ratio 1 ︰ 0.5 adds hydrargyrum oxydatum crudum, and limit edged stirs, and adds hydrargyrum oxydatum crudum, then adds Olibanum, Myrrha and Sanguis Draxonis, be stirred in the cold water of pouring 5-30 ℃ after ointment into and soak 1-2 week releasing fire-toxin, changes water every day one time, ointment after releasing fire-toxin is pulled out, heat fused, evenly stand is coated on cloth or on paper, and cooling rear stripping and slicing obtains (uniform painting 3-5g on the cloth of every 8 cm * 10cm or paper).
Compatibility of the present invention is reasonable, easily produces, and easily pastes and uses, during use, plaster is applied ointment or plaster at painful area, effectively treat the pain that various tumors cause, as hepatocarcinoma, pulmonary carcinoma, cancer of pancreas, breast carcinoma, the pain that the various tumors such as ovarian cancer, bladder cancer, carcinoma of prostate, colorectal cancer cause all can be used, reliable and stable, good effect, instant effect, acting duration is long, has no side effect, easy to use, simple, safe and reliable.
The specific embodiment
Below in conjunction with embodiment, the specific embodiment of the present invention is described in further detail.
Embodiment 1
The plaster of the present embodiment comprises crude drug by weight: Radix Aconiti 5g, Radix Aconiti Kusnezoffii 5g, Radix Angelicae Sinensis 13g, dry maxima skin 9g, Fructus Crotonis 1.5g, Resina garciniae 27g, Semen Strychni 1.5g, Rhizoma Anemones Raddeanae 9g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Radix Et Rhizoma Rhei 14g, Crinis Carbonisatus 9g, Fructus Forsythiae 9g, Nidus Vespae 14g, Radix Ampelopsis 14g, Fructus Tribuli 14g, Semen Momordicae 14g, Squama Manis sheet 11g, Olibanum 11g, Myrrha 11g and Sanguis Draxonis 5g, wherein, by Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Angelicae Sinensis, dry maxima skin, Fructus Crotonis, Resina garciniae, Semen Strychni, Rhizoma Anemones Raddeanae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Crinis Carbonisatus, Fructus Forsythiae, Nidus Vespae, Radix Ampelopsis, Fructus Tribuli, Semen Momordicae and Squama Manis sheet mix to obtain hybrid medicine, add the Oleum sesami identical with hybrid medicine weight, fried after immersion 2h, until the white medicine in hybrid medicine explodes into micro-Huang, elimination medicinal residues, obtain medicine fluid, heating is refined oil to dripping into pearl, then presses medicine fluid, hydrargyrum oxydatum crudum weight ratio 1 ︰ 0.5 adds hydrargyrum oxydatum crudum, and limit edged stirs, and adds hydrargyrum oxydatum crudum, then adds Olibanum, Myrrha and Sanguis Draxonis, be stirred in the cold water of pouring 5-30 ℃ after ointment into and soak 1-2 week releasing fire-toxin, changes water every day one time, ointment after releasing fire-toxin is pulled out, heat fused, evenly stand is coated on cloth or on paper, cooling rear stripping and slicing and get final product uniform painting 3g on the cloth of every 8 cm * 10cm or paper.
Embodiment 2
The plaster of the present embodiment comprises crude drug by weight: Radix Aconiti 6g, Radix Aconiti Kusnezoffii 6g, Radix Angelicae Sinensis 15g, dry maxima skin 10g, Fructus Crotonis 2g, Resina garciniae 30g, Semen Strychni 2g, Rhizoma Anemones Raddeanae 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 6g, Radix Et Rhizoma Rhei 15g, Crinis Carbonisatus 10g, Fructus Forsythiae 10g, Nidus Vespae 15g, Radix Ampelopsis 15g, Fructus Tribuli 15g, Semen Momordicae 15g, Squama Manis sheet 12g, Olibanum 12g, Myrrha 12g and Sanguis Draxonis 6g, wherein, by Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Angelicae Sinensis, dry maxima skin, Fructus Crotonis, Resina garciniae, Semen Strychni, Rhizoma Anemones Raddeanae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Crinis Carbonisatus, Fructus Forsythiae, Nidus Vespae, Radix Ampelopsis, Fructus Tribuli, Semen Momordicae and Squama Manis sheet mix to obtain hybrid medicine, add the Oleum sesami identical with hybrid medicine weight, fried after immersion 2h, until the white medicine in hybrid medicine explodes into micro-Huang, elimination medicinal residues, obtain medicine fluid, heating is refined oil to dripping into pearl, then presses medicine fluid, hydrargyrum oxydatum crudum weight ratio 1 ︰ 0.5 adds hydrargyrum oxydatum crudum, and limit edged stirs, and adds hydrargyrum oxydatum crudum, then adds Olibanum, Myrrha and Sanguis Draxonis, be stirred in the cold water of pouring 5-30 ℃ after ointment into and soak 1-2 week releasing fire-toxin, changes water every day one time, ointment after releasing fire-toxin is pulled out, heat fused, evenly stand is coated on cloth or on paper, cooling rear stripping and slicing and get final product uniform painting 4g on the cloth of every 8 cm * 10cm or paper.
Embodiment 3
The plaster of the present embodiment comprises crude drug by weight: Radix Aconiti 7g, Radix Aconiti Kusnezoffii 7g, Radix Angelicae Sinensis 17g, dry maxima skin 11g, Fructus Crotonis 2.5g, Resina garciniae 33g, Semen Strychni 2.5g, Rhizoma Anemones Raddeanae 11g, Pseudobulbus Bletillae (Rhizoma Bletillae) 7g, Radix Et Rhizoma Rhei 16g, Crinis Carbonisatus 11g, Fructus Forsythiae 11g, Nidus Vespae 16g, Radix Ampelopsis 16g, Fructus Tribuli 16g, Semen Momordicae 16g, Squama Manis sheet 13g, Olibanum 13g, Myrrha 13g and Sanguis Draxonis 7g, wherein, by Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Angelicae Sinensis, dry maxima skin, Fructus Crotonis, Resina garciniae, Semen Strychni, Rhizoma Anemones Raddeanae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Crinis Carbonisatus, Fructus Forsythiae, Nidus Vespae, Radix Ampelopsis, Fructus Tribuli, Semen Momordicae and Squama Manis sheet mix to obtain hybrid medicine, add the Oleum sesami identical with hybrid medicine weight, fried after immersion 2h, until the white medicine in hybrid medicine explodes into micro-Huang, elimination medicinal residues, obtain medicine fluid, heating is refined oil to dripping into pearl, then presses medicine fluid, hydrargyrum oxydatum crudum weight ratio 1 ︰ 0.5 adds hydrargyrum oxydatum crudum, and limit edged stirs, and adds hydrargyrum oxydatum crudum, then adds Olibanum, Myrrha and Sanguis Draxonis, be stirred in the cold water of pouring 5-30 ℃ after ointment into and soak 1-2 week releasing fire-toxin, changes water every day one time, ointment after releasing fire-toxin is pulled out, heat fused, evenly stand is coated on cloth or on paper, cooling rear stripping and slicing and get final product uniform painting 5g on the cloth of every 8 cm * 10cm or paper.
The present invention it is to be noted; technological core of the present invention is prescription and compatibility amount; the preparation method of plaster is conventional method; do not ask to give special protection; as long as the either method that reaches technique effect all can, the medicament that every use prescription of the present invention and consumption are made all belongs to the scope of the application's protection.
In said medicine, wherein:
Radix Aconiti: expelling wind and removing dampness, antalgic; For anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type, have a pain.Be used for the treatment of the diseases such as anemofrigid-damp arthralgia, arthralgia.
Radix Aconiti Kusnezoffii: recuperating depleted YANG is mended fire, dispelling cold and removing dampness, has spasmolytic, analgesia, wind-damp dispelling and the effect such as antipyretic.
Radix Angelicae Sinensis: energy blood circulation promoting and blood stasis dispelling, the disease that treatment amenorrhea is obstructed and blood stasis stagnates and swells and ache.
Cutis Bufonis: heat-clearing and toxic substances removing, diuretic relieving distension, for controlling carbuncle, toxic swelling, scrofula, tumor, infantile malnutrition abdominal distention, chronic tracheitis.
Fructus Crotonis: hot in nature, acrid in the mouth, function removing mass, relieve oedema or abdominal distension through diuresis or purgation, vomiting phlegm and saliva by emesis, contribute to control distension and fullness of the chest and abdomen shoot, constipation, dysentery, edema enlarged abdomen, phlegm retention dyspnea with fullness of the chest, acute throat trouble sore throat, carbuncle, malignant boil scabies due to constipation due to pathogenic cold constipation, ascites swelling, cold-evil's food stagnation.
Resina garciniae: detumescence, blood stasis dispelling, hemostasis, is used for the treatment of swollen ulcer drug, stubborn dermatitis malignant boil, damage, the disease such as hemorrhage.
Semen Strychni: removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.For rheumatoid arthritis stubborn, paralysis and numbness, injury from falling down, ulcer sore pain; Poliomyelitis sequela, rheumatoid arthritis.
Rhizoma Anemones Raddeanae: wind-damp dispelling, subduing inflammation.For anemofrigid-damp arthralgia, spasm of the limbs, arthralgia, carbuncle turgescence canker.
The Pseudobulbus Bletillae (Rhizoma Bletillae): claim again Pseudobulbus Bletillae (Rhizoma Bletillae), cure mainly: astringing to arrest bleeding, detumescence and promoting granulation.For hemoptysis, spit blood, traumatic hemorrhage, sore swollen toxin, chapped skin; Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.
Radix Et Rhizoma Rhei: have and attack the effects such as stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances, cure mainly: excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; Edema abdominal distention; Dysuria; Conjunctival congestion; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Gastropyretic vomiting; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Blood-retention; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Lump in the abdomen; Traumatic injury; Pyretic toxicity carbuncle and ulcer; Erysipelas; Scald.
Crinis Carbonisatus: there is the effect of astringing to arrest bleeding, blood stasis dispelling diuresis, cure mainly haematemesis, spitting of blood, hematuria, have blood in stool, epistaxis, dysentery, stranguria with blood, traumatic hemorrhage and the disease such as woman uterine bleeding and dysuria.
Fructus Forsythiae: the effect of tool heat-clearing and toxic substances removing, the knot evacuation of pus that disappears, for antibacterial, antiinflammatory, antipyretic, tell in town, diuresis heart tonifying, anti-liver damage, analgesia, suppress the effects such as phosphodiesterase, antiviral, blood pressure lowering, inhibition elastin laminin enzyme activity, antiendotoxin,
Nidus Vespae: dispel the wind, counteracting toxic substances, parasite killing, pain relieving, antiallergic, cures mainly toothache due to dental caries, sore swollen toxin, acute mastitis, scrofula, skin stubborn dermatitis, fungal infection of hand and foot, allergic constitution.
Radix Ampelopsis: heat-clearing and toxic substances removing; Removing obstruction for relieving pain; Promoting tissue regeneration and ulcer healing, cures mainly: sore swollen toxin, scrofula, scalds eczema, pyrexial malaria, infantile convulsion, dysentery, hemorrhoidal hamorrhage, anal fistula, leucorrhea, traumatic injury, traumatic hemorrhage.
Fructus Tribuli: suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic.Be used for having a headache dizzy, distending pain in the chest and hypochondrium, breast closes acute mastitis, conjunctival congestion cataracta, rubella pruritus.
Semen Momordicae: mass dissipating and swelling eliminating, counteracting toxic substances is treated skin ulcer.For sore swollen toxin, acute mastitis, scrofula, anal fistula, chronic eczema, tinea alba.
Squama Manis sheet: have invigorate blood circulation, the effect such as stimulating milk secretion, detumescence, evacuation of pus, for diseases such as galactostasis, carbuncle sore tumefacting virus, group's warp, arthralgia.
Olibanum: regulating qi and activating blood, analgesic therapy, chases after poison.Cure mainly coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Myrrha, has another name called myrrh, cures mainly breast abdomen stasis of blood pain, dysmenorrhea, amenorrhea, lump in the abdomen, traumatic injury, carbuncle skin infection, acute appendicitis, conjunctival congestion and swelling pain.There are the effects such as promoting blood circulation and stopping pain, detumescence and promoting granulation.
Sanguis Draxonis: promoting blood circulation to remove blood stasis for oral administration, analgesic therapy, external hemostasia and promoting granulation, sore, cures mainly congestion amenorrhea, dysmenorrhea, postpartum stagnation; Lump in the abdomen mass in the abdomen, breast ventral spine pain; Traumatic injury, congestion swells and ache; Traumatic hemorrhage, ulcer being unable to heal.
Hydrargyrum oxydatum crudum, Oleum sesami are commercially available prod (known technology).
Effective combination of said medicine, supports mutually, and through science preparation, has the effect for the treatment of cancerous pain, have no side effect, and stable curative effect, instant effect, long action time, effective percentage is high, and cost is low, dose homeostasis, patient's no pain, easy to use, simple, effective, clinical data fully proves.Concrete relevant clinical data of the present invention is as follows:
1, select the standard of case
1.1 physical data
Effective case 180 examples are included in this research altogether in, are divided at random two groups.In treatment group 120 examples, male 71 examples, female's 49 examples, the oldest 79 years old, minimum 32 years old, 65.5 years old mean age; Matched group 60 examples, male 34 examples, female's 26 examples, the oldest 78 years old, minimum 30 years old, 63.3 years old mean age.Two groups of disease distribution situations: treatment group hepatocarcinoma 32 examples, pulmonary carcinoma 16 examples, cancer of pancreas 16 examples, breast carcinoma 24 examples, ovarian cancer 12 examples, bladder cancer 8 examples, carcinoma of prostate 8 examples, colorectal cancer 4 examples; Matched group 12 Cases of Liver Cancer, pulmonary carcinoma 6 examples, cancer of pancreas 4 examples, mammary cancer 10 example, ovarian cancer 6 examples, bladder cancer 4 examples, carcinoma of prostate 6 examples, colorectal cancer 8 examples, cancer of biliary duct 4 examples.Two groups of basic conditions and disease distribution situation are similar.All cases all derive from the inpatient of in January, 2011 to 2013 year December, and are diagnosed as malignant tumor patient through pathology or cytology or typical imaging examination.
1.2 inclusive criteria age >=18 year old, estimate that life cycle is more than two months.Do not receive chemotherapy in the recent period and during treatment, radiotherapy, viewing duration tranquilizer, analgesic.
1.3 exclusion standard compliances are poor, have dysnoesia or Patient with Mental Disease, and self judges the pain degree person of having any problem; There is serious externally applied ointment skin allergy person; Gestation and nurture phase women; Medication maybe can not complete regulation person's course for the treatment of in accordance with regulations; Data is not completely without legally constituted authority meter curative effect person.
1.4 diagnostic criteria
Pain diagnostic criteria: pain degree classification, according to main suit's Pain Grading (VRS), is divided into 4 grades.0 grade painless; 1 grade (mild pain): though there is pain sense to stand, and can orthobiosis, sleep is interference-free; 2 grades (moderate pain): pain is obvious, is impatient at, and requires to take analgesic, and sleep is disturbed; 3 grades (severe pain): sharp ache is impatient at, and needs analgesic, sleep is seriously interfered, can be with autonomic nervous dysfunction's performance or positive position.Take 1～2 grade as light moderate pain.
therapeutic scheme
2.1 treatment groups: with warm water cleaning painful area skin, dry or dry, external application plaster of the present invention, every note, with 2.5～3 days, is cleaned skin with safflower oil while changing plaster, after 12 hours, forces on again.
2.2 matched groups: with indometacin bolt, receive anus treatment, the same treatment group of method, oral each 4 of placebo, every day 3 times, clothes, are used in conjunction 7 d after the meal.
2.3 observation index and method
2.3.1 pain relief degree is understood the best analgesic effect after medication.Alleviate completely (CR): completely painless after treatment.Partial rcsponse (PR): pain obviously alleviates before compared with administration, sleeps substantially interference-free, can orthobiosis.Slight alleviate (MR): pain alleviates before compared with administration, but still feels obvious pain, and sleep is still disturbed.Invalid (NR): with before treatment relatively pain without alleviating.CR+PR+MR is effective.
2.3.2 pain relieving onset time starts to alleviate the time of experiencing from first medication to pain, and in min, less than 1 min person calculates by 0 min.
2.3.3 the pain relieving persistent period is from medication first, and after each medication, pain starts to alleviate to pain and recovers degree required time before medication, in h.Less than 0.5 h person, by 0 h, surpasses 0.5 h and is less than 1 h person by 1 h.
2.3.4 quality of life scoring is evaluated according to Kamofsky scoring method quality of life, if compare integration before treatment and after treatment, to increase >=10 minutes persons be raising; Increase or reduce 10 minutes persons of < for stable; Reduce >=10 and be divided into reduction.
2.3.5 in untoward reaction treatment front and back and therapeutic process, detect routine blood test, hepatic and renal function, four of blood clottings and electrocardiogram.With reference to WHO cancer therapy drug untoward reaction calibration standard.
2.4 statistical analysis application SPSS13.0 softwares carry out statistical procedures, and measurement data adopts t check, and technical data is checked with X2.
result
The comparison of 3.1 liang of group total effectses, in Table 1.Two groups of complete remission rates compare P < 0.01, and treatment group is better than matched group.
Table 1 liang group pain palliation efficacy comparison
Note: with matched group comparison,
p< 0.01, (table 2～3 are same).
Organize pain relieving onset, persistent period comparison for 3.2 liang, in Table 2
Table 2 liang group pain relieving onset time, the comparison of pain relieving persistent period (
± s)
Two groups of pain relieving onset time comparisons, no significant difference (P > 0.05), illustration time of origin is suitable; And the comparison of pain relieving persistent period, two groups of differences have highly significant meaning (P < 0.01), illustrate that therapeutic alliance group analgesic effect is better, and 12 taste tumor suppression capsules have played important function.
The scoring of 3.3 quality of lifes is compared, in Table 3.Two groups of obvious effective rate comparisons, P < 0.01, treatment group is better than matched group.
Table 3 liang group quality of life comparison (
± s)
3.4 untoward reaction are treatment group 3 examples relatively, and matched group 8 examples have perspiration in various degree, but general vital sign is steady; After two groups of medications, at aspects such as routine blood test, hepatic and renal function, electrolyte, electrocardiograms, be showed no significant change.
conclusion
By above-mentioned, shown, drug matching science of the present invention, consumption is reasonable, reliable and stable, therapeutic effect is good, instant effect, acting duration is long, has no side effect, and the obvious clinical symptoms of reduction of patient on cancerous pain, for canurous ache patients provides good treatment condition, effective percentage reaches 98.3%, is that one on Chinese medicine and pharmacy created greatly, has actual clinical meaning, be that one on cancerous pain medicine innovated greatly, have good society and economic benefit.
Claims (4)
1. a plaster for the treatment of cancerous pain, is characterized in that, this plaster comprises crude drug by weight: Radix Aconiti 5-7g, Radix Aconiti Kusnezoffii 5-7g, Radix Angelicae Sinensis 13-17g, dry maxima skin 9-11g, Fructus Crotonis 1.5-2.5g, Resina garciniae 27-33g, Semen Strychni 1.5-2.5g, Rhizoma Anemones Raddeanae 9-11g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-7g, Radix Et Rhizoma Rhei 14-16g, Crinis Carbonisatus 9-11g, Fructus Forsythiae 9-11g, Nidus Vespae 14-16g, Radix Ampelopsis 14-16g, Fructus Tribuli 14-16g, Semen Momordicae 14-16g, Squama Manis sheet 11-13g, Olibanum 11-13g, Myrrha 11-13g and Sanguis Draxonis 5-7g, wherein, by Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Angelicae Sinensis, dry maxima skin, Fructus Crotonis, Resina garciniae, Semen Strychni, Rhizoma Anemones Raddeanae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Crinis Carbonisatus, Fructus Forsythiae, Nidus Vespae, Radix Ampelopsis, Fructus Tribuli, Semen Momordicae and Squama Manis sheet mix to obtain hybrid medicine, add the Oleum sesami identical with hybrid medicine weight, fried after immersion 2h, until the white medicine in hybrid medicine explodes into micro-Huang, elimination medicinal residues, obtain medicine fluid, heating is refined oil to dripping into pearl, then presses medicine fluid, hydrargyrum oxydatum crudum weight ratio 1 ︰ 0.5 adds hydrargyrum oxydatum crudum, and limit edged stirs, and adds hydrargyrum oxydatum crudum, then adds Olibanum, Myrrha and Sanguis Draxonis, be stirred in the cold water of pouring 5-30 ℃ after ointment into and soak 1-2 week releasing fire-toxin, changes water every day one time, the ointment after releasing fire-toxin is pulled out, and heat fused, evenly stand is coated on cloth or on paper, cooling rear stripping and slicing and get final product.
2. the plaster for the treatment of cancerous pain according to claim 1, is characterized in that, this plaster comprises crude drug by weight: Radix Aconiti 5g, Radix Aconiti Kusnezoffii 5g, Radix Angelicae Sinensis 13g, dry maxima skin 9g, Fructus Crotonis 1.5g, Resina garciniae 27g, Semen Strychni 1.5g, Rhizoma Anemones Raddeanae 9g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Radix Et Rhizoma Rhei 14g, Crinis Carbonisatus 9g, Fructus Forsythiae 9g, Nidus Vespae 14g, Radix Ampelopsis 14g, Fructus Tribuli 14g, Semen Momordicae 14g, Squama Manis sheet 11g, Olibanum 11g, Myrrha 11g and Sanguis Draxonis 5g, wherein, by Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Angelicae Sinensis, dry maxima skin, Fructus Crotonis, Resina garciniae, Semen Strychni, Rhizoma Anemones Raddeanae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Crinis Carbonisatus, Fructus Forsythiae, Nidus Vespae, Radix Ampelopsis, Fructus Tribuli, Semen Momordicae and Squama Manis sheet mix to obtain hybrid medicine, add the Oleum sesami identical with hybrid medicine weight, fried after immersion 2h, until the white medicine in hybrid medicine explodes into micro-Huang, elimination medicinal residues, obtain medicine fluid, heating is refined oil to dripping into pearl, then presses medicine fluid, hydrargyrum oxydatum crudum weight ratio 1 ︰ 0.5 adds hydrargyrum oxydatum crudum, and limit edged stirs, and adds hydrargyrum oxydatum crudum, then adds Olibanum, Myrrha and Sanguis Draxonis, be stirred in the cold water of pouring 5-30 ℃ after ointment into and soak 1-2 week releasing fire-toxin, changes water every day one time, ointment after releasing fire-toxin is pulled out, heat fused, evenly stand is coated on cloth or on paper, cooling rear stripping and slicing and get final product uniform painting 3g on the cloth of every 8 cm * 10cm or paper.
3. the plaster for the treatment of cancerous pain according to claim 1, is characterized in that, this plaster comprises crude drug by weight: Radix Aconiti 6g, Radix Aconiti Kusnezoffii 6g, Radix Angelicae Sinensis 15g, dry maxima skin 10g, Fructus Crotonis 2g, Resina garciniae 30g, Semen Strychni 2g, Rhizoma Anemones Raddeanae 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 6g, Radix Et Rhizoma Rhei 15g, Crinis Carbonisatus 10g, Fructus Forsythiae 10g, Nidus Vespae 15g, Radix Ampelopsis 15g, Fructus Tribuli 15g, Semen Momordicae 15g, Squama Manis sheet 12g, Olibanum 12g, Myrrha 12g and Sanguis Draxonis 6g, wherein, by Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Angelicae Sinensis, dry maxima skin, Fructus Crotonis, Resina garciniae, Semen Strychni, Rhizoma Anemones Raddeanae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Crinis Carbonisatus, Fructus Forsythiae, Nidus Vespae, Radix Ampelopsis, Fructus Tribuli, Semen Momordicae and Squama Manis sheet mix to obtain hybrid medicine, add the Oleum sesami identical with hybrid medicine weight, fried after immersion 2h, until the white medicine in hybrid medicine explodes into micro-Huang, elimination medicinal residues, obtain medicine fluid, heating is refined oil to dripping into pearl, then presses medicine fluid, hydrargyrum oxydatum crudum weight ratio 1 ︰ 0.5 adds hydrargyrum oxydatum crudum, and limit edged stirs, and adds hydrargyrum oxydatum crudum, then adds Olibanum, Myrrha and Sanguis Draxonis, be stirred in the cold water of pouring 5-30 ℃ after ointment into and soak 1-2 week releasing fire-toxin, changes water every day one time, ointment after releasing fire-toxin is pulled out, heat fused, evenly stand is coated on cloth or on paper, cooling rear stripping and slicing and get final product uniform painting 4g on the cloth of every 8 cm * 10cm or paper.
4. the plaster for the treatment of cancerous pain according to claim 1, is characterized in that, this plaster comprises crude drug by weight: Radix Aconiti 7g, Radix Aconiti Kusnezoffii 7g, Radix Angelicae Sinensis 17g, dry maxima skin 11g, Fructus Crotonis 2.5g, Resina garciniae 33g, Semen Strychni 2.5g, Rhizoma Anemones Raddeanae 11g, Pseudobulbus Bletillae (Rhizoma Bletillae) 7g, Radix Et Rhizoma Rhei 16g, Crinis Carbonisatus 11g, Fructus Forsythiae 11g, Nidus Vespae 16g, Radix Ampelopsis 16g, Fructus Tribuli 16g, Semen Momordicae 16g, Squama Manis sheet 13g, Olibanum 13g, Myrrha 13g and Sanguis Draxonis 7g, wherein, by Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Angelicae Sinensis, dry maxima skin, Fructus Crotonis, Resina garciniae, Semen Strychni, Rhizoma Anemones Raddeanae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Crinis Carbonisatus, Fructus Forsythiae, Nidus Vespae, Radix Ampelopsis, Fructus Tribuli, Semen Momordicae and Squama Manis sheet mix to obtain hybrid medicine, add the Oleum sesami identical with hybrid medicine weight, fried after immersion 2h, until the white medicine in hybrid medicine explodes into micro-Huang, elimination medicinal residues, obtain medicine fluid, heating is refined oil to dripping into pearl, then presses medicine fluid, hydrargyrum oxydatum crudum weight ratio 1 ︰ 0.5 adds hydrargyrum oxydatum crudum, and limit edged stirs, and adds hydrargyrum oxydatum crudum, then adds Olibanum, Myrrha and Sanguis Draxonis, be stirred in the cold water of pouring 5-30 ℃ after ointment into and soak 1-2 week releasing fire-toxin, changes water every day one time, ointment after releasing fire-toxin is pulled out, heat fused, evenly stand is coated on cloth or on paper, cooling rear stripping and slicing and get final product uniform painting 5g on the cloth of every 8 cm * 10cm or paper.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410287521.XA CN104013818A (en) | 2014-06-25 | 2014-06-25 | Plaster for treating cancer pains |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410287521.XA CN104013818A (en) | 2014-06-25 | 2014-06-25 | Plaster for treating cancer pains |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105770827A (en) * | 2016-04-19 | 2016-07-20 | 贵阳中医学院 | Medicinal patch treating cancer pain and preparation method thereof |
| CN106237088A (en) * | 2016-08-25 | 2016-12-21 | 杨明军 | A kind of Chinese medicine plaster |
| CN110575474A (en) * | 2019-09-24 | 2019-12-17 | 佘建华 | plaster for treating pain and preparation method thereof |
| CN111297991A (en) * | 2018-12-10 | 2020-06-19 | 刘志皋 | Formula and preparation method of internal medicinal liquor |
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2014
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| 张汝涛等: "加味万应膏临床应用举隅", 《贵阳中医学院学报》 * |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105770827A (en) * | 2016-04-19 | 2016-07-20 | 贵阳中医学院 | Medicinal patch treating cancer pain and preparation method thereof |
| CN105770827B (en) * | 2016-04-19 | 2020-02-14 | 贵阳中医学院 | Medicinal paper for treating cancer pain and preparation method thereof |
| CN106237088A (en) * | 2016-08-25 | 2016-12-21 | 杨明军 | A kind of Chinese medicine plaster |
| CN111297991A (en) * | 2018-12-10 | 2020-06-19 | 刘志皋 | Formula and preparation method of internal medicinal liquor |
| CN110575474A (en) * | 2019-09-24 | 2019-12-17 | 佘建华 | plaster for treating pain and preparation method thereof |
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