CN103585519A - Traditional Chinese medicine preparation for curing chloasma - Google Patents

Abstract

The invention relates to a traditional Chinese medicine preparation for curing chloasma. The traditional Chinese medicine preparation is prepared from radix angelicae, semen cassiae, radix bupleuri, radix ophiopogonis, polygonum multiflorum, anise, Chinese date, trichosanthes peel, fruit of Chinese wolfberry, tangerine seed, henry woodbetony root and semen coicis. The traditional Chinese medicine preparation can be clinically used for curing chloasma.

Description

A kind of Chinese medicine preparation for the treatment of chloasma

Technical field

The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine preparation for the treatment of chloasma.

Background technology

Chloasma is commonly called as " butterfly spot ", " chloasma hepaticum " or " cyasma ".Mainly occur in face, take cheekbone portion, buccal, nose, forehead, chin portion as main.For the brown of obscure boundary Chu or the patch of black, mostly be symmetry.The appearance of chloasma is most relevant with endocrine, especially relevant with women's estrogen level, menoxenia, gestation, takes contraceptive or liver function is bad and chronic nephropathy all may occur chloasma.The inventor draws through long-term practice, and the Chinese medicine brown patch of harnessing the Yellow River has better effect, obtains good effect.

Summary of the invention

The object of the present invention is to provide the Chinese medicine preparation of the treatment chloasma that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.

The present invention adopts the Radix Angelicae Dahuricae, Semen Cassiae, Radix Bupleuri, Radix Ophiopogonis, Radix Polygoni Multiflori, anise, Fructus Jujubae, Pericarpium Trichosanthis, Fructus Lycii, Fructus Citri tangerinae core, Radix Pedicularis Henryi, Semen Coicis according to certain compatibility requirement, through being processed into.

Preparing Chinese medicine of the present invention is made by following raw material medicaments: Radix Angelicae Dahuricae 30-50 part, Semen Cassiae 30-50 part, Radix Bupleuri 20-40 part, Radix Ophiopogonis 20-40 part, Radix Polygoni Multiflori 20-40 part, anistree 20-40 part, Fructus Jujubae 10-20 part, Pericarpium Trichosanthis 10-20 part, Fructus Lycii 10-20 part, Fructus Citri tangerinae core 10-20 part, Radix Pedicularis Henryi 10-20 part, Semen Coicis 10-20 part.

Optimum weight part of raw material of Chinese medicine medicine of the present invention is: 40 parts of the Radixs Angelicae Dahuricae, 40 parts of Semen Cassiaes, 30 parts of Radix Bupleuri, 30 parts of Radix Ophiopogonis, 30 parts of Radix Polygoni Multiflori, 30 parts of anises, 15 parts, Fructus Jujubae, 15 parts of Pericarpium Trichosanthiss, 15 parts of Fructus Lycii, 15 parts of Fructus Citri tangerinae cores, 15 parts of Radix Pedicularis Henryis, 15 parts of Semen Coiciss.

The pharmacological action of Chinese medicine of the present invention is as follows:

The Radix Angelicae Dahuricae: pungent, warm.Return lung, spleen, stomach warp.Expelling wind and removing dampness, logical pain relieving, the detumescence and apocenosis stolen.For headache due to common cold, supraorbital bone pain, toothache, nasal obstruction, nasal sinusitis, domination of damp pathogen chronic diarrhea, women leucorrhea, ulcer sores, venom etc.

Semen Cassiae: sweet, bitter, salty, be slightly cold.Return liver, large intestine channel.Clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation.Return liver, kidney, large intestine channel.The effect that has fat-reducing.Control wind heat acute conjunctivitis, optic atrohic blindness, nyctalopia, hypertension, hepatitis, cirrhotic ascites, habitual constipation.

Radix Bupleuri: bitter, pungent, be slightly cold, return liver, gallbladder meridian.Evacuation is brought down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI.For stagnation of QI due to depression of the liver, pain in chest and hypochondrium.

Radix Ophiopogonis: sweet, micro-hardship, be slightly cold.Return lung, stomach, heart channel.Nourishing YIN and moistening the lung, reinforcing stomach reg fluid, relieving restlessness clears away heart-fire.Cure mainly dryness of the lung dry cough, the deficiency of YIN, Tianjin wound is thirsty, the cards such as vexed insomnia.

Radix Polygoni Multiflori: hardship; Sweet; Puckery; Slightly warm in nature.Cure mainly blood deficiency anemia; Light-headedness; Cardiopalmus; Insomnia; The soreness of the waist and knees of the hepatic and renal YIN deficiency; Early whitening of beard and hair; Tinnitus; Seminal emission; Dryness of the intestine constipation; Chronic malaria body is empty; Rubella pruritus; Carbuncle sore; Scrofula; Hemorrhoid.Anistree: pungent, sweet, warm.Return liver,kidney,spleen, stomach warp.Cold expelling, regulate the flow of vital energy, pain relieving.For colic of cold type stomachache, chills and pain of the waist and kness, fear of cold vomiting, the disturbance of lower legs due to pathogenic cold and dampness etc.

Fructus Jujubae: sweet, warm.Return spleen, stomach warp.Invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, relaxes the property of medicine.For insufficiency of the spleen anorexia and loose stool, fatigue and weakness, blood deficiency and yellow complexion and women's internal organs, mind is uneasy, protection healthy energy etc.

Pericarpium Trichosanthis: sweet, bitter, cold.Attach to the lung and stomach meridians.Removing heat from the lung and dissipating phlegm, promoting the circulation of QI relieving stuffiness of the chest by dispersing aggregation of pathogens.For cough due to lung-heat, breast side of body painful abdominal mass pain, laryngopharynx swelling and pain, the diseases such as nodules of the breast acute mastitis.

Fructus Lycii: sweet, flat.Return liver, kidney channel.Invigorating the liver and kidney, improving eyesight.For deficiency of the liver and kindey, soreness of waist seminal emission, has a dizzy spell, and visual deterioration, quenches one's thirst etc.

Fructus Citri tangerinae core: flat, bitter, return liver, kidney channel.Regulate the flow of vital energy, eliminating stagnation, pain relieving.For inguinal hernia, painful and swollen testis, acute mastitis swells and ache.

Radix Pedicularis Henryi: sweet, micro-hardship, temperature.Fill blood, bone and muscle strengthening, strengthening the spleen and stomach.For dizziness and tinnitus, palpitation and short breath, brothers' flaccidity is soft, bones and muscles pain, bronchitis, food stagnation of child, malnutrition.

Semen Coicis: sweet, light, be slightly cold.Return spleen, lung, kidney channel.Dampness removing spleen invigorating, arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus.For edema, beriberi, dribbling urination, the leukorrhagia of having loose bowels, rheumatic arthralgia, the contracture of muscle arteries and veins, lung abscess, acute appendicitis, verruca plana etc.

Chinese medicine preparation of the present invention was in 2006 to 2012 the routine patients of clinical observation chloasma 60, and clinical report is as follows:

1, physical data

In 60 routine patients, in age 23-65 year, 41.6 years old mean age was all women.

2, diagnostic criteria

The < < traditional Chinese medical science disease Standardization of diagnosis and curative effect > > that diagnosis basis State Administration of Traditional Chinese Medicine issues:

Face is filbert to dark brown, well-defined patch, and symmetry distributes conventionally, NIP performance and squama; Without obvious subjective symptoms; Women is multiple, mainly occurs in after adolescence; The state of an illness can have seasonality, and the Chang Xiachong winter is light.Visible two side of body distending pains of symptom, susceptible to lose temper due to restlessness, belch, often because emotional factors brings out, premenstrual distending pain of the breast, has a headache with both sides more so, insomnia and dreamful sleep, dim complexion, there are the symptoms such as petechia on red tongue, both sides.

3, exclusion standard

Gestation or women breast-feeding their children; Be associated with liver, cardiovascular disease person; Malignant tumor patient; In 4 weeks, once systematic treating was crossed patient; During treatment, end treatment or change medicine, method person; Cannot judge curative effect or the data judgement person that entirely do not affect the treatment.

4, Therapeutic Method

4.1 prescriptions: Radix Angelicae Dahuricae 40g, Semen Cassiae 40g, Radix Bupleuri 30g, Radix Ophiopogonis 30g, Radix Polygoni Multiflori 30g, anistree 30g, Fructus Jujubae 15g, Pericarpium Trichosanthis 15g, Fructus Lycii 15g, Fructus Citri tangerinae core 15g, Radix Pedicularis Henryi 15g, Semen Coicis 15g.

4.2 methods of preparation and use: said medicine routinely technique is made decoction, every day 2 times, 10 days were 1 course for the treatment of at 1 dose of every day.

5, therapeutic outcome:

5.1 formulate with reference to < < Chinese medicine Clinical Researches of New Drugs guideline > >:

Cure: naked eyes are depending on the mottle area >90% that disappears, and color disappears substantially; Point system is calculated, decline index >=0.8 after treatment.

Effective: naked eyes are depending on the mottle area >60% that disappears, and color is obviously thin out; Point system is calculated, decline index >=0.5 after treatment.

Take a turn for the better: naked eyes are depending on the mottle area >30% that disappears, and color is thin out; Point system is calculated, decline index >=0.3 after treatment.

Invalid: naked eyes are depending on the mottle area <30% that disappears, and change color is not obvious; Point system is calculated, and after treatment, decline index becomes≤0.

5.2 results: in 60 routine patients, cure 32 examples (53.3%), effective 13 examples (21.7%), 11 examples that take a turn for the better (18.3%), invalid 4 examples (6.7%), total effective rate is 93.3%.

6, model case

6.1 seasons, female, 34 years old, there is chloasma in face, and increase the weight of year by year, and it is upper that to 1cm on geisoma line, along the line down to the corners of the mouth, on inside cord, point arises from eyebrow, and mid point is in bridge of the nose outside, and on out conductor, point, at temple, along cheekbone outside, presents dark brown a slice, symmetry.Be diagnosed as chloasma.Take medicine of the present invention, 1 dose of every day, after 1 course for the treatment of, chloasma starts to dissipate, and scope is dwindled, and continues to take 2 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.

6.2 poplars, female, 47 years old, face played speckle, and companion's poor appetite is sleepy weak, sleeps night and feels unwell, half congealed during stool.Preceeded menorrhea, many, the color of amount secretly have clot, and light red tongue is tender indentation, yellow fur, moderate pulse.Existing buccal, the visible map shape of two cheekbone yellowish-brown patch.Be diagnosed as chloasma.Take medicine of the present invention, 1 dose of every day, after 1 course for the treatment of, brown patch color is thin out, sleep slightly good, and tired alleviating.Continue to take 2 courses for the treatment of, recovery from illness, continues to take 1 course for the treatment of and consolidates, and follows up a case by regular visits to without recurrence after 1 year.

The specific embodiment

Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.

Embodiment 1, treat a Chinese medicine preparation for chloasma, be by Radix Angelicae Dahuricae 30g, Semen Cassiae 30g, Radix Bupleuri 20g, Radix Ophiopogonis 20g, Radix Polygoni Multiflori 20g, anistree 20g, Fructus Jujubae 10g, Pericarpium Trichosanthis 10g, Fructus Lycii 10g, Fructus Citri tangerinae core 10g, Radix Pedicularis Henryi 10g, Semen Coicis 10g make.

Embodiment 2, treat a Chinese medicine preparation for chloasma, be by Radix Angelicae Dahuricae 40g, Semen Cassiae 40g, Radix Bupleuri 30g, Radix Ophiopogonis 30g, Radix Polygoni Multiflori 30g, anistree 30g, Fructus Jujubae 15g, Pericarpium Trichosanthis 15g, Fructus Lycii 15g, Fructus Citri tangerinae core 15g, Radix Pedicularis Henryi 15g, Semen Coicis 15g make.

Embodiment 3, treat a Chinese medicine preparation for chloasma, be by Radix Angelicae Dahuricae 50g, Semen Cassiae 50g, Radix Bupleuri 40g, Radix Ophiopogonis 40g, Radix Polygoni Multiflori 40g, anistree 40g, Fructus Jujubae 20g, Pericarpium Trichosanthis 20g, Fructus Lycii 20g, Fructus Citri tangerinae core 20g, Radix Pedicularis Henryi 20g, Semen Coicis 20g make.

Claims (2)

1. treat a Chinese medicine preparation for chloasma, it is characterized in that it is to be made by following raw material medicaments:

Radix Angelicae Dahuricae 30-50 part, Semen Cassiae 30-50 part, Radix Bupleuri 20-40 part, Radix Ophiopogonis 20-40 part, Radix Polygoni Multiflori 20-40 part, anistree 20-40 part, Fructus Jujubae 10-20 part, Pericarpium Trichosanthis 10-20 part, Fructus Lycii 10-20 part, Fructus Citri tangerinae core 10-20 part, Radix Pedicularis Henryi 10-20 part, Semen Coicis 10-20 part.

2. Chinese medicine preparation according to claim 1, is characterized in that it is to be made by following raw material medicaments:

40 parts of the Radixs Angelicae Dahuricae, 40 parts of Semen Cassiaes, 30 parts of Radix Bupleuri, 30 parts of Radix Ophiopogonis, 30 parts of Radix Polygoni Multiflori, 30 parts of anises, 15 parts, Fructus Jujubae, 15 parts of Pericarpium Trichosanthiss, 15 parts of Fructus Lycii, 15 parts of Fructus Citri tangerinae cores, 15 parts of Radix Pedicularis Henryis, 15 parts of Semen Coiciss.