CN102552753B - Chinese medicinal composition for treating uterine fibroid - Google Patents

Chinese medicinal composition for treating uterine fibroid Download PDF

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Publication number
CN102552753B
CN102552753B CN 201210022591 CN201210022591A CN102552753B CN 102552753 B CN102552753 B CN 102552753B CN 201210022591 CN201210022591 CN 201210022591 CN 201210022591 A CN201210022591 A CN 201210022591A CN 102552753 B CN102552753 B CN 102552753B
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parts
fructus
radix
medicinal composition
chinese medicinal
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CN102552753A (en
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金伟
董涛
王健
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Haimen Linjiang biological medicine science and Technology Pioneer Park Co Ltd
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金伟
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Abstract

The invention discloses a Chinese medicinal composition for treating uterine fibroid. The Chinese medicinal composition is prepared from Chinese angelica, red paeony root, cyperus rotundus, immature bitter orange, dogwood, peony root bark, stem of climbing entada, airpotato yam rhizome, akebia fruit, stone-like omphalia, dried orange peel, cassia twig, tuckahoe, herb of pilosella-leaved drymoglossum, cortex lycii, thinleaf milkwort root bark, keel, oyster, scorch-fried malt, hawthorn fruit and medicated leaven and liquorice. The Chinese medicinal composition is clinically used for treating the uterine fibroid.

Description

A kind of Chinese medicine composition for the treatment of hysteromyoma
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of hysteromyoma.
Background technology
Hysteromyoma is the modal benign tumors of female sex organs, also is the modal tumor of human body, is mainly formed by smooth muscle cell proliferation, and a small amount of fibrous connective tissue is arranged therebetween.Be common in 30-50 year women, according to statistics, at least 20% the women of child-bearing age have hysteromyoma.Modern medicine adopts operation or the treatment of the methods such as hormone interference more, because it is large and have certain side effect on the impact of female normal physiological function, and recurs easily drug withdrawal after.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, human body had no side effect, cure the Chinese medicine composition of the treatment hysteromyoma of rear difficult recurrence.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Cyperi, Fructus Aurantii Immaturus, Fructus Corni, Cortex Moutan, Semen Bauhiniae championii, Rhizoma Dioscoreae Bulbiferae, August short, bristly hair or beard, Omphalia, Pericarpium Citri Reticulatae, Ramulus Cinnamomi, Poria, newspaper tree lotus, Cortex Lycii, Radix Polygalae, Os Draconis, Concha Ostreae, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Radix Glycyrrhizae, according to certain compatibility requirement, form through specific processes.
Preparing Chinese medicine composition of the present invention is made by following raw material medicaments: Radix Angelicae Sinensis 10-30 part, Radix Paeoniae Rubra 10-20 part, Rhizoma Cyperi 10-30 part, Fructus Aurantii Immaturus 5-15 part, Fructus Corni 10-30 part, Cortex Moutan 10-20 part, Semen Bauhiniae championii 20-40 part, Rhizoma Dioscoreae Bulbiferae 5-15 part, August short, bristly hair or beard 5-15 part, Omphalia 5-15 part, Pericarpium Citri Reticulatae 10-30 part, Ramulus Cinnamomi 10-20 part, Poria 10-20 part, newspaper tree lotus 20-40 part, Cortex Lycii 5-15 part, Radix Polygalae 10-30 part, Os Draconis 10-20 part, Concha Ostreae 10-30 part, each 10-30 part of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Radix Glycyrrhizae 10-30 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 20 parts of Radix Angelicae Sinensis, 15 parts of Radix Paeoniae Rubra, 20 parts of Rhizoma Cyperis, 10 parts of Fructus Aurantii Immaturuss, 20 parts of Fructus Corni, 15 parts of Cortex Moutans, 30 parts of Semen Bauhiniae championiis, 10 parts of Rhizoma Dioscoreae Bulbiferaes, August, short, bristly hair or beard was 10 parts, 10 parts of Omphalias, 20 parts of Pericarpium Citri Reticulataes, 15 parts of Ramulus Cinnamomi, 15 parts in Poria, 30 parts in newspaper tree lotus, 10 parts of Cortex Lycii, 20 parts of Radix Polygalaes, 15 parts of Os Draconis, 20 parts of Concha Ostreaes, each 20 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), 20 parts in Radix Glycyrrhizae.
The pharmacological action of Chinese medicine of the present invention is as follows:
Radix Angelicae Sinensis: sweet, hot, warm, return liver, the heart, spleen channel.Enrich blood, invigorate blood circulation, regulating menstruation, pain relieving.Be used for heart-liver blood deficiency, ulcer sores etc.
Radix Paeoniae Rubra: bitter, be slightly cold.Return liver, spleen channel.Clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.Be used for maculae caused by violent heat pathogen, discharging fresh blood stool, carbuncle skin infection etc.
Rhizoma Cyperi: hot, sweet, little hardship, flat.Return liver, tri-jiao channel.Regulate the flow of vital energy resolving depression, regulating menstruation, antiabortive.Be used for distending pain over the hypochondrium, gastral cavity abdomen feeling of fullness pain, abdominal pain during menstruation etc.
Fructus Aurantii Immaturus: bitter, hot, cold.Return spleen, stomach, liver, heart channel.The dispelling the stagnated QI removing food stagnancy reduces phlegm except painful abdominal mass.Stop feeling of fullness distending pain, constipation, gastroptosis, proctoptosis etc. in being used for stagnating.
Fructus Corni: acid, tepor, return liver, kidney channel.Liver and kidney tonifying, convergence are taken off admittedly.Cure mainly and have a dizzy spell, the cards such as deafness and tinnitus.
Cortex Moutan: arduous, cool, be slightly cold.GUIXIN, sweet, kidney, lung meridian.Heat clearing away, promoting blood circulation to remove blood stasis.Be used for the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, tell nosebleed, deficiency of YIN osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatism pyretic arthralgia etc.
Semen Bauhiniae championii: bitter, Xin Wen.Return liver, stomach warp.Promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling.Be used for stagnation of QI and blood, distending pain over the hypochondrium, gastric abscess, traumatic injury.
Rhizoma Dioscoreae Bulbiferae: bitter, cold, return lung, Liver Channel.The eliminating stagnation wart that disappears, heat-clearing and toxic substances removing, cooling blood for hemostasis.Cure mainly goiter, sore throat, carbuncle sore tumefacting virus, lung-heat cough with asthma etc.
August short, bristly hair or beard: little hardship, property are flat.Return liver, stomach, urinary bladder channel.Dispersing the stagnated liver-QI for regulating the stomach, promoting blood circulation and stopping pain, hard masses softening and resolving, diuresis.Be used for stagnation of liver-QI and stomach-QI, gastral cavity abdomen, the side of body help distending pain, and diet does not disappear, and dysentery is just let out, hernia pain, lumbago, amenorrhea dysmenorrhea, goiter scrofula, malignant tumor etc.
Omphalia: bitter, cold.Return stomach, large intestine channel.Removing food stagnancy, parasite killing.Be used for abdominal pain due to worm stagnation etc.
Pericarpium Citri Reticulatae: hot, bitter, warm, return spleen, stomach, lung meridian.Regulate the flow of vital energy and transfer, stopping nausea and vomiting by lowering the adverse flow of QI, drying dampness to eliminate phlegm.It is full vexed to be used for chest and diaphragm, abdominal distention, anorexia, vomiting etc.
Ramulus Cinnamomi: hot, sweet, warm, GUIXIN, lung, urinary bladder channel.The diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI.Be used for anemofrigid cold, congealing cold with blood stasis, phlegm retention, syndrome of water-retention.
Poria: sweet, light, flat.GUIXIN, spleen, lung, kidney channel.Eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.Be used for dysuria, the edema distension, the phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite is had loose bowels, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.
Drymoglossum Herba Drymoglossi: sweet, light, little cold.Return liver, lung meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, hemostasis.Be used for jaundice due to damp-heat, conjunctival congestion and swelling pain, parotitis, lymphadenitis, traumatic injury.
Cortex Lycii: sweet, cold.Return lung, kidney channel.Clearind deficient heat, purte the white, removing heat from blood.Be used for hectic fever due to deficiency of YIN, hectic fever due to YIN-deficiency night sweat, the infantile malnutrition heating, dyspnea and cough due to lung-heat is spitted blood, and hematuria is quenched one's thirst etc.
Radix Polygalae: bitter, hot, tepor, GUIXIN, kidney, lung meridian.Mind tranquilizing and the heart calming eliminates the phlegm and has one's ideas straightened out, the dissipation carbuncle.Be used for palpitation with fear, insomnia forgetfulness, phlegmatic mental confusion, epilepsy is gone mad.
Os Draconis: puckery, sweet, flat, GUIXIN, liver, kidney, large intestine channel.Tranquilizing mind, suppressing the hyperactive liver and subsiding YANG is restrained astringent or styptic treatment for spontaneous sweating.Be used for cardiopalmus, insomnia, forgetful, dizzy.
Concha Ostreae: salty, puckery, be slightly cold, return liver, kidney channel.Suppressing the hyperactive liver and subsiding YANG, hard masses softening and resolving is restrained astringent or styptic treatment for spontaneous sweating.Be mainly used in excessive rising of liver-YANG, have a dizzy spell, sucutaneous nodule, scrofula , lumps in the chest and abdomen etc.
Fructus Hordei Germinatus: sweet, flat.Return spleen, stomach warp.The removing food stagnancy relieving dyspepsia, galactopoiesis.Cure mainly food stagnation, abdominal distention is had loose bowels, nausea and vomiting, inappetence etc.
Fructus Crataegi: sour, sweet, tepor.Return spleen, stomach, Liver Channel.Promoting digestion and invigorating the stomach, the circulation of qi promoting dissipating blood stasis.Be used for eating accumulation, abdominal distention, dysentery, hernia swells and ache etc.
Massa Medicata Fermentata: sweet, hot, warm.Return spleen, stomach warp.Stomach function regulating helps digestion.Be used for the eating accumulation card, distension and fullness in the abdomen, lack of appetite are indigestion and loss of appetite, borborygmus diarrhoea etc.
Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.The QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, relieving spasm to stop pain, the mediation property of medicine.Be used for abundant expectoration cough, pathopyretic ulcer.
Reuse Semen Bauhiniae championii, Drymoglossum Herba Drymoglossi in the side, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Cyperi, Cortex Moutan, Semen Bauhiniae championii, newspaper tree lotus promoting flow of QI and blood, Rhizoma Dioscoreae Bulbiferae, August short, bristly hair or beard, Concha Ostreae, Omphalia, Radix Polygalae, Os Draconis blood stasis-eliminating and stagnation-dissipating, hard masses softening and resolving, during Fructus Aurantii Immaturus, Pericarpium Citri Reticulatae, Poria, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) are regulated the flow of vital energy and are transferred, invigorating the spleen and regulating the stomach, the Cortex Lycii heat-clearing and toxic substances removing, Ramulus Cinnamomi promoting the flow of QI-blood by warming the meridian, Fructus Corni improve the body microcirculation, improve immunity of organisms, the Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.Above medicine is played the effect of blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, hard masses softening and resolving altogether, improves immunity of organisms, thereby cures hysteromyoma.
Chinese medicine composition of the present invention was in 2006 to 2011 clinical observation hysteromyoma 80 routine patients, and clinical report is as follows:
1, physical data
Among the 80 routine patients, minimum 26 years old of age, maximum 50 years old, 39 years old mean age.
2, diagnostic criteria
(1) menorrhagia, menostaxis or irregular bleeding, lump can appear in lower abdomen, and minority has pain and pressure symptom, or companion's basin blood; (2) uterus increases, and matter is hard; (3) surveying uterine cavity increases or is out of shape; (4) examine and touch crowning when scraping in the uterine cavity; (5) B ultrasonic and/or uteroscopy can assist to check.
3, Therapeutic Method
3.1 prescription: Radix Angelicae Sinensis 20g, Radix Paeoniae Rubra 15g, Rhizoma Cyperi 20g, Fructus Aurantii Immaturus 10g, Fructus Corni 20g, Cortex Moutan 15g, Semen Bauhiniae championii 30g, Rhizoma Dioscoreae Bulbiferae 10g, August short, bristly hair or beard 10g, Omphalia 10g, Pericarpium Citri Reticulatae 20g, Ramulus Cinnamomi 15g, Poria 15g, newspaper tree lotus 30g, Cortex Lycii 10g, Radix Polygalae 20g, Os Draconis 15g, Concha Ostreae 20g, each 20g of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Radix Glycyrrhizae 20g.
3.2 preparation method: said medicine routinely technique is made decoction.
3.3 instructions of taking: each 1 dose, every day 2 times, stop using menstrual period, and 30 days is 1 course for the treatment of.
4, therapeutic outcome:
4.1 curative effect judging standard is with reference to " new Chinese medicine guideline of clinical investigations " second volume.Recovery from illness: clinical symptom disappearance, muscular tumor disappears, the eumenorrhea; Produce effects: eumenorrhea, or the change of muscular tumor disappearance menstrual symptom thing, muscular tumor is dwindled>0.5cm; Effectively: clinical symptom relief or disappearance, muscular tumor is dwindled, and menstruation is unchanged without improvement or muscular tumor, the eumenorrhea; Invalid: the unchanged or increase of muscular tumor, menstruation is without change.
4.2 result: 54 examples of fully recovering (67.5%), produce effects 11 examples (13.75%), effective 10 examples (12.5%), 5 examples (6.25%) do not heal.Total effective rate is 93.75% by recovery from illness, produce effects and effectively.
5, model case
5.1 Liu is 39 years old, few when many during usual leukorrhagia, the yellow skin idol folder blood streak, dim through circumstances in which people get things ready for a trip purple, the many folders of amount clot, lower abdomen pain, companion's xerostomia wish drink, susceptible to lose temper due to restlessness, the poor dreaminess of sleeping, red tongue with yellow fur is little greasy, thready and rapid pulse, and B ultrasonic shows: uterus 6.8cm * 5.6cm * 5.1cm, the cervix uteri rear sees that 2.5cm * 2.1cm hangs down echo light group, the prompting hysteromyoma.Process is treated 3 courses for the treatment of, menstruation and leukorrhagia normal, and remaining disease disappears, and the check B ultrasonic shows that hysteromyoma disappears.
5.2 Tan, 42 years old, closely over the past half year, and delay of menstrual cycle, few through the row amount, the color purple is dim, and is dripping unclean through going, menostaxis, even the whole month is unclean, and pain is alleviated after going few abdomen pain, getting fomentation, light red tongue, and tongue is little is bored with deep and hesitant pulse in vain.B ultrasonic: anterior uterine wall is seen 3.7cm * 3.2cm echo light group, the prompting hysteromyoma.Serve on 3 checks course for the treatment of, B ultrasonic: anterior uterine wall is seen 1.2cm * 1.4cm size echo light group, and the prompting hysteromyoma dwindles, continues to take 2 courses for the treatment of, and the B ultrasonic check: hysteromyoma disappears.
The specific embodiment
Embodiment 1, and a kind of Chinese medicine for the treatment of hysteromyoma is by Radix Angelicae Sinensis 20g, Radix Paeoniae Rubra 15g, Rhizoma Cyperi 20g, Fructus Aurantii Immaturus 10g, Fructus Corni 20g, Cortex Moutan 15g, Semen Bauhiniae championii 30g, Rhizoma Dioscoreae Bulbiferae 10g, August short, bristly hair or beard 10g, Omphalia 10g, Pericarpium Citri Reticulatae 20g, Ramulus Cinnamomi 15g, Poria 15g, newspaper tree lotus 30g, Cortex Lycii 10g, Radix Polygalae 20g, Os Draconis 15g, Concha Ostreae 20g, each 20g of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Radix Glycyrrhizae 20g makes.
Embodiment 2, and a kind of Chinese medicine for the treatment of hysteromyoma is by Radix Angelicae Sinensis 10g, Radix Paeoniae Rubra 10g, Rhizoma Cyperi 10g, Fructus Aurantii Immaturus 5g, Fructus Corni 10g, Cortex Moutan 10g, Semen Bauhiniae championii 20g, Rhizoma Dioscoreae Bulbiferae 5g, August short, bristly hair or beard 5g, Omphalia 5g, Pericarpium Citri Reticulatae 10g, Ramulus Cinnamomi 10g, Poria 10g, newspaper tree lotus 20g, Cortex Lycii 5g, Radix Polygalae 10g, Os Draconis 10g, Concha Ostreae 10g, each 10g of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Radix Glycyrrhizae 10g makes.
Embodiment 3, and a kind of Chinese medicine for the treatment of hysteromyoma is by Radix Angelicae Sinensis 30g, Radix Paeoniae Rubra 20g, Rhizoma Cyperi 30g, Fructus Aurantii Immaturus 15g, Fructus Corni 30g, Cortex Moutan 20g, Semen Bauhiniae championii 40g, Rhizoma Dioscoreae Bulbiferae 15g, August short, bristly hair or beard 15g, Omphalia 15g, Pericarpium Citri Reticulatae 30g, Ramulus Cinnamomi 20g, Poria 20g, newspaper tree lotus 40g, Cortex Lycii 15g, Radix Polygalae 30g, Os Draconis 20g, Concha Ostreae 30g, each 30g of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata), Radix Glycyrrhizae 30g makes.

Claims (2)

1. Chinese medicine composition for the treatment of hysteromyoma is characterized in that it is to be made by following raw material medicaments:
Radix Angelicae Sinensis 10-30 part Radix Paeoniae Rubra 10-20 part Rhizoma Cyperi 10-30 part Fructus Aurantii Immaturus 5-15 part Fructus Corni 10-30 part
Cortex Moutan 10-20 part Semen Bauhiniae championii 20-40 part Rhizoma Dioscoreae Bulbiferae 5-15 part Fructus Akebiae 5-15 part Omphalia 5-15 part
Pericarpium Citri Reticulatae 10-30 part Ramulus Cinnamomi 10-20 part Poria 10-20 part Drymoglossum Herba Drymoglossi 20-40 part Cortex Lycii 5-15 part
Each 10-30 part Radix Glycyrrhizae 10-30 part of Radix Polygalae 10-30 part Os Draconis 10-20 part Concha Ostreae 10-30 part JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata).
2. Chinese medicine composition according to claim 1 is characterized in that it is to be made by following raw material medicaments:
20 parts of 10 parts of Fructus Corni of 20 parts of Fructus Aurantii Immaturuss of 15 portions of Rhizoma Cyperis of 20 parts of Radix Paeoniae Rubra of Radix Angelicae Sinensis
10 parts of 10 parts of Omphalias of 10 parts of Fructus Akebiaes of 30 parts of Rhizoma Dioscoreae Bulbiferaes of 15 parts of Semen Bauhiniae championiis of Cortex Moutan
10 parts of 30 parts of Cortex Lycii of 15 parts of Drymoglossum Herba Drymoglossis of 15 parts of Poria of 20 parts of Ramulus Cinnamomi of Pericarpium Citri Reticulatae
20 parts in each 20 portions of Radix Glycyrrhizae of 20 parts of JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) of 15 portions of Concha Ostreaes of 20 parts of Os Draconis of Radix Polygalae.
CN 201210022591 2012-01-05 2012-01-05 Chinese medicinal composition for treating uterine fibroid Expired - Fee Related CN102552753B (en)

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Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104398722A (en) * 2014-11-26 2015-03-11 辛秀芳 Traditional Chinese medicine for treating liver qi stagnation type uterine myoma
CN104491221A (en) * 2014-12-15 2015-04-08 杨连华 Traditional Chinese medicine for treating hysteromyoma with stagnation of phlegm and blood stasis
CN104524005A (en) * 2014-12-23 2015-04-22 代玉红 Traditional Chinese medicine for treating myoma of uterus due to qi stagnation and blood stasis
CN104524039A (en) * 2015-01-21 2015-04-22 陈吉美 Traditional Chinese medicine for treating uterine fibroids

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* Cited by examiner, † Cited by third party
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CN1123357C (en) * 1999-06-25 2003-10-08 刘永香 Powdered medicine for conditioning viscera and whole body

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