CN104524039A - Traditional Chinese medicine for treating uterine fibroids - Google Patents

Traditional Chinese medicine for treating uterine fibroids Download PDF

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Publication number
CN104524039A
CN104524039A CN201510029173.0A CN201510029173A CN104524039A CN 104524039 A CN104524039 A CN 104524039A CN 201510029173 A CN201510029173 A CN 201510029173A CN 104524039 A CN104524039 A CN 104524039A
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chinese medicine
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陈吉美
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/37Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/40Cornaceae (Dogwood family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/69Polygalaceae (Milkwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

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Abstract

The invention relates to a traditional Chinese medicine for treating uterine fibroids. The traditional Chinese medicine is prepared from common threewingnut root, rush, largehead atractylodes rhizome, immature bitter orange, common macrocarpium fruits, rhizome of largeleaf Japanese ginseng, fiveleaf akebia fruits, glaucescent fissistigma root, Indian buead, Chinese wolfberry root-bark, thinleaf milkwort root-bark, fossilizid and liquorice root. The traditional Chinese medicine can be clinically used for treating uterine fibroids.

Description

A kind of Chinese medicine for the treatment of hysteromyoma
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine for the treatment of hysteromyoma.
Background technology
Hysteromyoma is the modal benign tumors of female sex organs, forms primarily of smooth muscle cell proliferation, has a small amount of fibrous connective tissue therebetween.According to statistics, the women of child-bearing age of at least 20% have hysteromyoma.The method treatments such as the many employing operations of modern medicine or hormone interference, affect comparatively large because of it on female normal physiological function and have certain side effect, and easily recurring after drug withdrawal.The present inventor, through putting into practice for many years, utilizes treatment by Chinese herbs hysteromyoma to obtain good curative effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, to human non-toxic's side effect, cure after the Chinese medicine for the treatment of hysteromyoma that not easily recurs.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Radix Tripterygii Wilfordii, Medulla Junci, the Rhizoma Atractylodis Macrocephalae, long-pending reality, Fructus Corni, Rhizoma panacis majoris, Fructus Akebiae, Radix Fissistigmatis Glaucescentis, Poria, Cortex Lycii, Radix Polygalae, Os Draconis, Radix Glycyrrhizae, according to certain compatibility requirement, form through specific processes.
Prepare Chinese medicine of the present invention to be made up of following raw material medicaments: Radix Tripterygii Wilfordii 20-40 part, Medulla Junci 20-40 part, Rhizoma Atractylodis Macrocephalae 10-20 part, long-pending real 5-15 part, Fructus Corni 10-30 part, Rhizoma panacis majoris 5-15 part, Fructus Akebiae 5-15 part, Radix Fissistigmatis Glaucescentis 10-30 part, Poria 10-20 part, Cortex Lycii 5-15 part, Radix Polygalae 10-30 part, Os Draconis 10-20 part, Radix Glycyrrhizae 10-30 part.
Optimum weight part of raw material of Chinese medicine medicine of the present invention is: Radix Tripterygii Wilfordii 30 parts, Medulla Junci 30 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, long-pending real 10 parts, Fructus Corni 20 parts, Rhizoma panacis majoris 10 parts, Fructus Akebiae 10 parts, Radix Fissistigmatis Glaucescentis 20 parts, 15 parts, Poria, Cortex Lycii 10 parts, Radix Polygalae 20 parts, Os Draconis 15 parts, 20 parts, Radix Glycyrrhizae.
The pharmacological action of Chinese medicine of the present invention is as follows:
Radix Tripterygii Wilfordii: bitter, Xin Wen.Return liver, stomach warp.Promoting the circulation of QI to relieve pain, invigorating blood circulation addiction.For the blood addiction stagnation of QI, distending pain over the hypochondrium, stomach institute pain, traumatic injury.
Drymoglossum Herba Drymoglossi: sweet, light, micro-cool.Return liver, lung meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, hemostasis.For damp and hot yellow cellulitis, conjunctival congestion and swelling pain, parotitis, lymphadenitis, traumatic injury.
The Rhizoma Atractylodis Macrocephalae: bitter, be slightly cold.Return liver, spleen channel.Clearing away heat and cooling blood, addiction of dispelling of invigorating blood circulation.For maculae caused by violent heat pathogen, discharging fresh blood stool, carbuncle skin infection etc.
Long-pending real: bitter, acrid, cold.Return spleen, stomach, liver, heart channel.Dispelling the stagnated QI removing food stagnancy, reduces phlegm except painful abdominal mass.Stop in stagnant, feeling of fullness distending pain, constipation, gastroptosis, proctoptosis etc.
Fructus Corni: acid, tepor, returns liver, kidney channel.Liver and kidney tonifying, convergence are admittedly de-.Cure mainly and have a dizzy spell, the cards such as deafness and tinnitus.
Rhizoma panacis majoris: bitter, cold, returns lung, Liver Channel.Eliminating stagnation dispersing tumor, heat-clearing and toxic substances removing, cooling blood for hemostasis.Cure mainly tumor tumor, sore throat, carbuncle sore tumefacting virus, lung-heat cough with asthma etc.
Fructus Akebiae: micro-hardship, property are flat.Return liver, stomach, wing moon bright warp.Dispersing the stagnated liver-QI for regulating the stomach, promoting blood circulation and stopping pain, hard masses softening and resolving, diuresis.For stagnation of liver-QI and stomach-QI, institute's abdomen, the side of body help distending pain, and diet does not disappear, and dysentery is just let out, Shan gas pain, lumbago, amenorrhea dysmenorrhea, tumor tumor numbness carbuncle, malignant tumor etc.
Radix Fissistigmatis Glaucescentis: acrid, bitter, warm, returns spleen, stomach, lung meridian.Regulate the flow of vital energy in adjusting, stopping nausea and vomiting by lowering the adverse flow of QI, drying dampness to eliminate phlegm.Full vexed for septum pectorale, institute's abdominal distention and pain, anorexia, vomiting etc.
Poria: sweet, light, flat.GUIXIN, spleen, lung, kidney channel.Eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.For dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, has loose bowels, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.
Cortex Lycii: sweet, cold.Return lung, kidney channel.Clearind deficient heat, purte the white, removing heat from blood.For hectic fever due to deficiency of YIN, hectic fever due to YIN-deficiency night sweat, the long-pending heating of children's's skin ulcer, dyspnea and cough due to lung-heat, spit blood, hematuria, quenches one's thirst.
Radix Polygalae: bitter, pungent, tepor, GUIXIN, kidney, lung meridian.Mind tranquilizing and the heart calming, eliminates the phlegm and has one's ideas straightened out, dissipation carbuncle.For palpitation with fear, insomnia forgetfulness, phlegmatic mental confusion, insane pain is gone mad.
Os Draconis: puckery, sweet, flat, GUIXIN, liver, kidney, large intestine channel.Tranquilizing mind, suppressing the hyperactive liver and subsiding YANG, restrains astringent or styptic treatment for spontaneous sweating.For cardiopalmus, insomnia, forgetful, dizzy.
Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, relieving spasm to stop pain, the mediation property of medicine.For abundant expectoration cough, pathopyretic ulcer.
In side, Radix Tripterygii Wilfordii, Drymoglossum Herba Drymoglossi are monarch drug, tool promoting flow of QI and blood, heat-clearing and toxic substances removing, share, reach effect of invigorating blood circulation addiction, hard masses softening and resolving with other drug composition, improve immunity of organisms, thus cure hysteromyoma.
Detailed description of the invention
Embodiment 1, a kind of Chinese medicine for the treatment of hysteromyoma is by Radix Tripterygii Wilfordii 30g, Medulla Junci 30g, Rhizoma Atractylodis Macrocephalae 15g, and long-pending real 10g, Fructus Corni 20g, Rhizoma panacis majoris 10g, Fructus Akebiae 10g, Radix Fissistigmatis Glaucescentis 20g, Poria 15g, Cortex Lycii 10g, Radix Polygalae 20g, Os Draconis 15g, Radix Glycyrrhizae 20g makes.
Embodiment 2, a kind of Chinese medicine for the treatment of hysteromyoma is by Radix Tripterygii Wilfordii 20g, Medulla Junci 20g, Rhizoma Atractylodis Macrocephalae 10g, and long-pending real 5g, Fructus Corni 10g, Rhizoma panacis majoris 5g, Fructus Akebiae 5g, Radix Fissistigmatis Glaucescentis 10g, Poria 10g, Cortex Lycii 5g, Radix Polygalae 10g, Os Draconis 10g, Radix Glycyrrhizae 10g makes.
Embodiment 3, a kind of Chinese medicine for the treatment of hysteromyoma is by Radix Tripterygii Wilfordii 40g, Medulla Junci 40g, Rhizoma Atractylodis Macrocephalae 20g, and long-pending real 15g, Fructus Corni 30g, Rhizoma panacis majoris 15g, Fructus Akebiae 15g, Radix Fissistigmatis Glaucescentis 30g, Poria 20g, Cortex Lycii 15g, Radix Polygalae 30g, Os Draconis 20g, Radix Glycyrrhizae 30g makes.
Below, to Chinese medicine of the present invention in, 208 years to 2012 routine patients of clinical observation hysteromyoma 60, clinical report is as follows:
1, physical data 1
In 60 routine patients, minimum 24 years old of age, maximum 55 years old, 42 years old mean age.
2, diagnostic criteria
(1) menorrhagia, menostaxis or irregular bleeding, can there is lump in lower abdomen, minority has pain and pressure symptom, or companion's basin blood; (2) uterus increases, and matter is hard; (3) detect uterine cavity to increase or distortion; (4) examine when scraping and touch crowning in uterine cavity; B ultrasonic and/or uteroscopy can assist to check.
3, Therapeutic Method
3. 1 prescription: Radix Tripterygii Wilfordii 30g, Medulla Junci 30g, Rhizoma Atractylodis Macrocephalae 15g, long-pending real 10g, Fructus Corni 20g, Rhizoma panacis majoris 10g, Fructus Akebiae 10g, Radix Fissistigmatis Glaucescentis 20g, Poria 15g, Cortex Lycii 10g, Radix Polygalae 20g, Os Draconis 15g, Radix Glycyrrhizae 20g.
3. 2 preparation methoies: said medicine routinely technique makes decoction.
3. 3 instructions of taking: each 1 dose, every mouthful 2 times, menstrual period stop using, within 30 days, be 1 course for the treatment of.
4, therapeutic outcome:
4. 1 curative effect judging standard is with reference to " new Chinese medicine guideline of clinical investigations " second volume.
Recovery from illness: clinical symptom disappearance, muscular tumor disappears, the eumenorrhea;
Effective: the eumenorrhea, or muscular tumor disappearance menstrual symptom thing changes, and muscular tumor reduces >0. 5cm;
Effective: clinical symptom relief or disappearance, muscular tumor reduces, menstruation without improvement or muscular tumor unchanged, the eumenorrhea;
Invalid: muscular tumor is unchanged or increase, and menstruation is without change.
4.2 results: 44 examples of fully recovering (73.3%), effective 10 examples (16.7%), effective 4 examples (6.7%), do not heal 2
Example (3.3%).Total effective rate, by recovery from illness, effective and effectively, is 96.7%.
5, model case
5. 1 Chen, 36 years old, peasant, few time many during beginning leukorrhagia before February, the even fiery blood streak of yellow skin, dim through circumstances in which people get things ready for a trip purple, measure how fiery clot, lower abdomen pain, companion's xerostomia is for drink, susceptible to lose temper due to restlessness, poor dreaminess of sleeping, red tongue with yellow fur is micro-greasy, thready and rapid pulse, B ultrasonic shows: uterus 6. 4cm X 5. lcm X 4. 8cm, and the 2. low echo light groups of 3cm X 2. Ocm are seen at cervix uteri rear, prompting hysteromyoma.Through 3 courses for the treatment of of treatment, menstruation and leukorrhagia normal, remaining disease disappears, and check B ultrasonic shows that hysteromyoma disappears.
5.2 Liu, 42 years old, office clerks, closely over the past half year, the phase was thought in menstruation, and few through row amount, color purple is dim, dripping unclean through row, menostaxis, and even the whole month is unclean, and through the few abdomen pain of row, after obtaining fomentation, pain is alleviated, and light red tongue, tongue is micro-greasy in vain, deep and hesitant pulse.B ultrasonic: anterior uterine wall is shown in 3. 9cm X 3. 3cm echo light groups, prompting hysteromyoma.Serve on 3 checks course for the treatment of, B ultrasonic: anterior uterine wall is shown in 1. 3cm X 1. 2cm size echo light groups, prompting hysteromyoma reduces, continues to take 2 courses for the treatment of, and B ultrasonic is checked: hysteromyoma disappears.

Claims (2)

1. treat a Chinese medicine for hysteromyoma, it is characterized in that it is made up of following raw material medicaments: Radix Tripterygii Wilfordii 20-40 part, Medulla Junci 20-40 part, Rhizoma Atractylodis Macrocephalae 10-20 part, long-pending real 5-15 part, Fructus Corni 10-30 part, Rhizoma panacis majoris 5-15 part, be cut August 5-15 part, Radix Fissistigmatis Glaucescentis 10-30 part, Poria 10-20 part, Cortex Lycii 5-15 part, Radix Polygalae 10-30 part, Os Draconis 10-20 part, Radix Glycyrrhizae 10-30 part.
2. Chinese medicine according to claim 1, is characterized in that it is made up of following raw material medicaments: Radix Tripterygii Wilfordii 30 parts, Medulla Junci 30 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, long-pending real 10 parts, Fructus Corni 20 parts, Rhizoma panacis majoris 10 parts, be cut 10 parts August, Radix Fissistigmatis Glaucescentis 20 parts, 15 parts, Poria, Cortex Lycii 10 parts, Radix Polygalae 20 parts, Os Draconis 15 parts, 20 parts, Radix Glycyrrhizae.
CN201510029173.0A 2015-01-21 2015-01-21 Traditional Chinese medicine for treating uterine fibroids Pending CN104524039A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1679913A (en) * 2005-02-03 2005-10-12 贵阳德昌祥药业有限公司 Gynecologic rehabilitation capsules for treating gynecopathy
CN102552753A (en) * 2012-01-05 2012-07-11 金伟 Chinese medicinal composition for treating uterine fibroid
CN102716417A (en) * 2012-06-15 2012-10-10 祁连明 Traditional Chinese medicine preparation for treating gynaecopathia and preparation method of preparation
CN103272102A (en) * 2013-05-10 2013-09-04 张冠珍 Traditional Chinese medicine for treating myoma of uterus
CN103285295A (en) * 2013-06-14 2013-09-11 王保德 Traditional Chinese medicine preparation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1679913A (en) * 2005-02-03 2005-10-12 贵阳德昌祥药业有限公司 Gynecologic rehabilitation capsules for treating gynecopathy
CN102552753A (en) * 2012-01-05 2012-07-11 金伟 Chinese medicinal composition for treating uterine fibroid
CN102716417A (en) * 2012-06-15 2012-10-10 祁连明 Traditional Chinese medicine preparation for treating gynaecopathia and preparation method of preparation
CN103272102A (en) * 2013-05-10 2013-09-04 张冠珍 Traditional Chinese medicine for treating myoma of uterus
CN103285295A (en) * 2013-06-14 2013-09-11 王保德 Traditional Chinese medicine preparation

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