CN103656041B - A kind of Chinese medicine for the treatment of cervical cancer - Google Patents
A kind of Chinese medicine for the treatment of cervical cancer Download PDFInfo
- Publication number
- CN103656041B CN103656041B CN201310674302.2A CN201310674302A CN103656041B CN 103656041 B CN103656041 B CN 103656041B CN 201310674302 A CN201310674302 A CN 201310674302A CN 103656041 B CN103656041 B CN 103656041B
- Authority
- CN
- China
- Prior art keywords
- grams
- treatment
- cervical cancer
- chinese medicine
- radix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003814 drug Substances 0.000 title claims abstract description 30
- 206010008342 Cervix carcinoma Diseases 0.000 title claims abstract description 25
- 201000010881 cervical cancer Diseases 0.000 title claims abstract description 25
- 229940079593 drugs Drugs 0.000 claims abstract description 13
- 241000717739 Boswellia sacra Species 0.000 claims abstract description 5
- 241000628997 Flos Species 0.000 claims abstract description 5
- 239000004863 Frankincense Substances 0.000 claims abstract description 5
- 241001057584 Myrrha Species 0.000 claims abstract description 5
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 5
- 241000131808 Scolopendra Species 0.000 claims abstract description 5
- 241000522620 Scorpio Species 0.000 claims abstract description 5
- 210000000582 Semen Anatomy 0.000 claims abstract description 5
- 239000009490 scorpio Substances 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances data:image/svg+xml;base64,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 data:image/svg+xml;base64,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 O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 239000012535 impurity Substances 0.000 claims description 3
- 206010028980 Neoplasm Diseases 0.000 abstract description 6
- 230000001900 immune effect Effects 0.000 abstract description 2
- 208000002193 Pain Diseases 0.000 description 19
- 230000036407 pain Effects 0.000 description 18
- 239000008280 blood Substances 0.000 description 17
- 210000004369 Blood Anatomy 0.000 description 16
- 210000004185 Liver Anatomy 0.000 description 15
- 210000001015 Abdomen Anatomy 0.000 description 12
- 210000000952 Spleen Anatomy 0.000 description 10
- 201000011510 cancer Diseases 0.000 description 9
- 210000002216 Heart Anatomy 0.000 description 8
- 230000001105 regulatory Effects 0.000 description 8
- 206010001928 Amenorrhoea Diseases 0.000 description 7
- 206010022114 Injury Diseases 0.000 description 7
- 231100000614 Poison Toxicity 0.000 description 7
- 231100000540 amenorrhea Toxicity 0.000 description 7
- 201000000736 amenorrhea Diseases 0.000 description 7
- 206010037660 Pyrexia Diseases 0.000 description 6
- 210000000481 Breast Anatomy 0.000 description 5
- 206010027514 Metrorrhagia Diseases 0.000 description 5
- 206010046910 Vaginal haemorrhage Diseases 0.000 description 5
- 235000009508 confectionery Nutrition 0.000 description 5
- 230000001717 pathogenic Effects 0.000 description 5
- 206010007247 Carbuncle Diseases 0.000 description 4
- 210000003679 Cervix Uteri Anatomy 0.000 description 4
- 208000001848 Dysentery Diseases 0.000 description 4
- 206010018987 Haemorrhage Diseases 0.000 description 4
- 210000002784 Stomach Anatomy 0.000 description 4
- 206010042674 Swelling Diseases 0.000 description 4
- 230000000202 analgesic Effects 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 201000009030 carcinoma Diseases 0.000 description 4
- 238000002512 chemotherapy Methods 0.000 description 4
- 238000003745 diagnosis Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 201000004792 malaria Diseases 0.000 description 4
- 238000001959 radiotherapy Methods 0.000 description 4
- 230000002522 swelling Effects 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 239000003440 toxic substance Substances 0.000 description 4
- 206010000087 Abdominal pain upper Diseases 0.000 description 3
- 208000006820 Arthralgia Diseases 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 3
- 208000000059 Dyspnea Diseases 0.000 description 3
- 206010013975 Dyspnoeas Diseases 0.000 description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 210000004072 Lung Anatomy 0.000 description 3
- 206010027327 Menstrual disease Diseases 0.000 description 3
- 210000003205 Muscles Anatomy 0.000 description 3
- 206010047700 Vomiting Diseases 0.000 description 3
- 230000002159 abnormal effect Effects 0.000 description 3
- 231100000319 bleeding Toxicity 0.000 description 3
- 230000000740 bleeding Effects 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- 230000001737 promoting Effects 0.000 description 3
- 231100000486 side effect Toxicity 0.000 description 3
- 230000001225 therapeutic Effects 0.000 description 3
- 206010000060 Abdominal distension Diseases 0.000 description 2
- 210000000988 Bone and Bones Anatomy 0.000 description 2
- 210000003756 Cervix Mucus Anatomy 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 208000002173 Dizziness Diseases 0.000 description 2
- 206010051244 Dyschezia Diseases 0.000 description 2
- 208000005679 Eczema Diseases 0.000 description 2
- 210000000232 Gallbladder Anatomy 0.000 description 2
- 206010018836 Haematochezia Diseases 0.000 description 2
- 206010019233 Headache Diseases 0.000 description 2
- 208000008454 Hyperhidrosis Diseases 0.000 description 2
- 206010021118 Hypotonia Diseases 0.000 description 2
- 210000000936 Intestines Anatomy 0.000 description 2
- 210000003734 Kidney Anatomy 0.000 description 2
- 206010027336 Menstruation delayed Diseases 0.000 description 2
- 210000000214 Mouth Anatomy 0.000 description 2
- 206010033557 Palpitations Diseases 0.000 description 2
- 206010040943 Skin ulcer Diseases 0.000 description 2
- 206010068760 Ulcers Diseases 0.000 description 2
- 210000003932 Urinary Bladder Anatomy 0.000 description 2
- 230000001154 acute Effects 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 210000000038 chest Anatomy 0.000 description 2
- 201000004624 dermatitis Diseases 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 231100001003 eczema Toxicity 0.000 description 2
- 230000003419 expectorant Effects 0.000 description 2
- 239000003172 expectorant agent Substances 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 235000019525 fullness Nutrition 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 210000002429 large intestine Anatomy 0.000 description 2
- 210000004914 menses Anatomy 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000005180 public health Effects 0.000 description 2
- 238000004080 punching Methods 0.000 description 2
- 238000010926 purge Methods 0.000 description 2
- 230000001047 pyretic Effects 0.000 description 2
- 238000007086 side reaction Methods 0.000 description 2
- 231100000019 skin ulcer Toxicity 0.000 description 2
- 230000004206 stomach function Effects 0.000 description 2
- 201000010874 syndrome Diseases 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 206010000059 Abdominal discomfort Diseases 0.000 description 1
- 208000002399 Aphthous Stomatitis Diseases 0.000 description 1
- 206010003549 Asthenia Diseases 0.000 description 1
- 208000004429 Bacillary Dysentery Diseases 0.000 description 1
- 210000001124 Body Fluids Anatomy 0.000 description 1
- 206010006187 Breast cancer Diseases 0.000 description 1
- 241000208365 Celastraceae Species 0.000 description 1
- 206010010741 Conjunctivitis Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 206010061428 Decreased appetite Diseases 0.000 description 1
- 206010012335 Dependence Diseases 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 206010013990 Dysuria Diseases 0.000 description 1
- 206010015037 Epilepsy Diseases 0.000 description 1
- 208000001780 Epistaxis Diseases 0.000 description 1
- 206010016286 Febrile disease Diseases 0.000 description 1
- 206010017915 Gastroenteritis shigella Diseases 0.000 description 1
- 206010018498 Goitre Diseases 0.000 description 1
- 206010018830 Haematemesis Diseases 0.000 description 1
- 208000005252 Hepatitis A Diseases 0.000 description 1
- 206010019780 Hepatitis infectious Diseases 0.000 description 1
- 206010019909 Hernia Diseases 0.000 description 1
- 210000003026 Hypopharynx Anatomy 0.000 description 1
- 208000004404 Intractable Pain Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 210000003141 Lower Extremity Anatomy 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 208000004396 Mastitis Diseases 0.000 description 1
- 206010027295 Menometrorrhagia Diseases 0.000 description 1
- 206010029410 Night sweats Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010034960 Photophobia Diseases 0.000 description 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-N Picric acid Chemical compound data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='300px' height='300px' viewBox='0 0 300 300'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='300.0' height='300.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 237.8,148.0 L 221.6,148.0' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 221.6,148.0 L 205.4,148.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 205.4,148.0 L 180.7,190.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 193.1,149.5 L 175.8,179.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-12 atom-1' d='M 180.7,105.2 L 205.4,148.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 180.7,190.8 L 188.5,204.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 188.5,204.4 L 196.3,217.9' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-2 atom-6' d='M 180.7,190.8 L 131.2,190.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 194.0,253.3 L 191.7,257.3' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 191.7,257.3 L 189.4,261.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 230.6,238.6 L 234.5,238.6' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 234.5,238.6 L 238.4,238.6' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 230.6,228.7 L 234.5,228.7' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 234.5,228.7 L 238.4,228.7' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 131.2,190.8 L 106.5,148.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 136.1,179.5 L 118.8,149.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 106.5,148.0 L 94.4,148.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 94.4,148.0 L 82.3,148.0' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-7 atom-11' d='M 106.5,148.0 L 131.2,105.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 48.0,132.3 L 45.7,128.4' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 45.7,128.4 L 43.5,124.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 41.4,165.2 L 39.1,169.2' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 39.1,169.2 L 36.8,173.2' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 50.0,170.2 L 47.7,174.2' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 47.7,174.2 L 45.4,178.1' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 131.2,105.2 L 180.7,105.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 138.7,115.1 L 173.3,115.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 180.7,105.2 L 187.4,93.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 187.4,93.6 L 194.0,82.1' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 230.6,62.4 L 234.5,62.4' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 234.5,62.4 L 238.4,62.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 200.6,44.2 L 198.3,40.3' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 198.3,40.3 L 196.1,36.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 192.0,49.1 L 189.8,45.2' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 189.8,45.2 L 187.5,41.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='248.9' y='157.9' class='atom-0' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='262.6' y='157.9' class='atom-0' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='199.5' y='243.5' class='atom-3' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >N</text>
<text x='213.1' y='235.6' class='atom-3' style='font-size:13px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >+</text>
<text x='174.8' y='286.4' class='atom-4' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='188.4' y='278.5' class='atom-4' style='font-size:13px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='248.9' y='243.5' class='atom-5' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='51.1' y='157.9' class='atom-8' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >N</text>
<text x='64.8' y='150.0' class='atom-8' style='font-size:13px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >+</text>
<text x='26.4' y='115.1' class='atom-9' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='40.1' y='107.2' class='atom-9' style='font-size:13px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='26.4' y='200.7' class='atom-10' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='199.5' y='72.3' class='atom-13' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >N</text>
<text x='213.1' y='64.4' class='atom-13' style='font-size:13px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >+</text>
<text x='248.9' y='72.3' class='atom-14' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='262.6' y='64.4' class='atom-14' style='font-size:13px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='174.8' y='29.5' class='atom-15' style='font-size:19px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
</svg>
 data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='85px' height='85px' viewBox='0 0 85 85'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='85.0' height='85.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 69.6,41.4 L 63.6,41.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 63.6,41.4 L 57.7,41.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 57.7,41.4 L 50.7,53.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 54.2,41.9 L 49.3,50.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-12 atom-1' d='M 50.7,29.3 L 57.7,41.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 50.7,53.6 L 53.6,58.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 53.6,58.6 L 56.5,63.6' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-2 atom-6' d='M 50.7,53.6 L 36.7,53.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 55.8,69.1 L 53.8,72.4' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 53.8,72.4 L 51.9,75.8' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 62.3,67.1 L 66.0,67.1' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 66.0,67.1 L 69.7,67.1' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 62.3,64.3 L 66.0,64.3' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-3 atom-5' d='M 66.0,64.3 L 69.7,64.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 36.7,53.6 L 29.7,41.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 38.1,50.4 L 33.2,41.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 29.7,41.4 L 25.0,41.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 25.0,41.4 L 20.3,41.4' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-7 atom-11' d='M 29.7,41.4 L 36.7,29.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 14.4,39.3 L 12.5,35.9' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 12.5,35.9 L 10.6,32.6' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 12.5,44.1 L 10.6,47.5' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 10.6,47.5 L 8.6,50.8' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 15.0,45.5 L 13.0,48.9' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 13.0,48.9 L 11.1,52.2' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 36.7,29.3 L 50.7,29.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 38.8,32.1 L 48.6,32.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 50.7,29.3 L 53.2,24.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 53.2,24.9 L 55.8,20.5' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 62.3,17.2 L 66.0,17.2' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 66.0,17.2 L 69.7,17.2' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 57.7,14.3 L 55.7,11.0' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 55.7,11.0 L 53.8,7.6' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 55.2,15.7 L 53.3,12.4' style='fill:none;fill-rule:evenodd;stroke:#4284F4;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-13 atom-15' d='M 53.3,12.4 L 51.4,9.0' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='69.9' y='44.4' class='atom-0' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='74.0' y='44.4' class='atom-0' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='55.9' y='68.7' class='atom-3' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >N</text>
<text x='60.0' y='66.3' class='atom-3' style='font-size:3px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >+</text>
<text x='48.9' y='80.8' class='atom-4' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='53.0' y='78.4' class='atom-4' style='font-size:3px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='69.9' y='68.7' class='atom-5' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='13.9' y='44.4' class='atom-8' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >N</text>
<text x='18.0' y='42.0' class='atom-8' style='font-size:3px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >+</text>
<text x='6.9' y='32.3' class='atom-9' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='11.0' y='29.9' class='atom-9' style='font-size:3px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='6.9' y='56.6' class='atom-10' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='55.9' y='20.2' class='atom-13' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >N</text>
<text x='60.0' y='17.8' class='atom-13' style='font-size:3px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#4284F4' >+</text>
<text x='69.9' y='20.2' class='atom-14' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='74.0' y='17.8' class='atom-14' style='font-size:3px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >-</text>
<text x='48.9' y='8.0' class='atom-15' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
</svg>
 OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 208000008425 Protein Deficiency Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 208000008128 Pulmonary Tuberculosis Diseases 0.000 description 1
- 210000004915 Pus Anatomy 0.000 description 1
- 208000009146 Rhinoscleroma Diseases 0.000 description 1
- 210000000614 Ribs Anatomy 0.000 description 1
- 206010040007 Sense of oppression Diseases 0.000 description 1
- 210000003491 Skin Anatomy 0.000 description 1
- 206010040872 Skin infection Diseases 0.000 description 1
- 235000000336 Solanum dulcamara Nutrition 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 206010041660 Splenomegaly Diseases 0.000 description 1
- 210000001138 Tears Anatomy 0.000 description 1
- 206010044008 Tonsillitis Diseases 0.000 description 1
- 231100000765 Toxin Toxicity 0.000 description 1
- 210000001113 Umbilicus Anatomy 0.000 description 1
- 206010046901 Vaginal discharge Diseases 0.000 description 1
- 231100000611 Venom Toxicity 0.000 description 1
- 210000001048 Venoms Anatomy 0.000 description 1
- 206010052769 Vertigos Diseases 0.000 description 1
- 208000001877 Whooping Cough Diseases 0.000 description 1
- 230000003187 abdominal Effects 0.000 description 1
- 230000003213 activating Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000001166 anti-perspirant Effects 0.000 description 1
- 239000003213 antiperspirant Substances 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 201000009361 ascariasis Diseases 0.000 description 1
- 201000008275 breast carcinoma Diseases 0.000 description 1
- 230000001914 calming Effects 0.000 description 1
- 230000000973 chemotherapeutic Effects 0.000 description 1
- 230000001684 chronic Effects 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 201000008286 diarrhea Diseases 0.000 description 1
- 201000009910 diseases by infectious agent Diseases 0.000 description 1
- 201000008325 diseases of cellular proliferation Diseases 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000001815 facial Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 201000003872 goiter Diseases 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 201000003453 lung abscess Diseases 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 230000003340 mental Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000001617 migratory Effects 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 230000003000 nontoxic Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000000414 obstructive Effects 0.000 description 1
- 244000045947 parasites Species 0.000 description 1
- 244000052769 pathogens Species 0.000 description 1
- 230000001575 pathological Effects 0.000 description 1
- 201000005702 pertussis Diseases 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 229940114148 picric acid Drugs 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 230000025627 positive regulation of urine volume Effects 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000003014 reinforcing Effects 0.000 description 1
- 238000007665 sagging Methods 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 201000005113 shigellosis Diseases 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 230000002269 spontaneous Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000001502 supplementation Effects 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 231100000224 toxic side effect Toxicity 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 230000002936 tranquilizing Effects 0.000 description 1
- 229950002929 trinitrophenol Drugs 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 230000003639 vasoconstrictive Effects 0.000 description 1
- 239000002435 venom Substances 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Abstract
The invention discloses a kind of Chinese medicine for the treatment of cervical cancer, belong to the field of Chinese medicines.It is made up of the crude drug of following weight: Flos Sophorae (parched) 20 grams, Spica Prunellae 20 grams, Herba Scutellariae Barbatae 20 grams, Herba Hedyotidis Diffusae 20 grams, 15 grams, Pericarpium Citri Reticulatae Viride, Cortex Moutan 15 grams, 15 grams, Semen Persicae, the Radix Paeoniae Alba 15 grams, Carapax Trionycis 15 grams, Rhizoma Cyperi 15 grams, 15 grams, Poria, Cortex Phellodendri 15 grams, Ramulus Cinnamomi 10 grams, Radix Angelicae Sinensis 10 grams, Olibanum 10 grams, Myrrha 6 grams, 5 pieces, Fructus Jujubae, Rhizoma Coptidis 10 grams, Scorpio 6 grams, Scolopendra 10g, 3 grams, Radix Glycyrrhizae.The present invention effectively can improve the immunologic function of cervical cancer patient, improves body constitution, suppresses to kill cancerous cell, softens and reduces tumor, increases the ability to bear of cervical cancer patient, can prevent recurrence and transfer, increase the chance for the treatment of.
Description
Technical field
The present invention relates to a kind of Chinese medicine for the treatment of cervical cancer, belong to the field of Chinese medicines.
Background technology
Cervical cancer refers to the malignant tumor occurring in utero vaginal portion and cervical canal, is modal gynecologic malignant tumor, in the world, more than 20 ten thousand women are about had to die from cervical cancer every year, in developing country, cervical cancer then belongs to common multiple gynecological tumor, the seniority among brothers and sisters umber one.Early cervical carcinoma there will be colporrhagia or neoplasm, involves scope occur different Secondary Symptoms according to cancer.There will be frequent micturition, the symptom such as urgent micturition, constipation, lower limb swell and ache.
The western medical treatment mode of cervical cancer is the operative treatment known by us, radiotherapy, chemotherapy.Although western medical treatment instant effect, easily recurs, side effect is large.So in, the expectant treatment in late period, or the auxiliary treatment of Radiotherapy chemotherapy after early operation, the traditional Chinese medical science plays an important role, but the most uncertain therapeutic efficacy of existing Chinese medicine formula is cut.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine for the treatment of cervical cancer, all select natural Chinese medicinal herb, effectively can treat cervical cancer.
Technical scheme of the present invention is: a kind of Chinese medicine for the treatment of cervical cancer, is characterized in that, is made up of the crude drug of following weight: Flos Sophorae (parched) 20 grams, Spica Prunellae 20 grams, Herba Scutellariae Barbatae 20 grams, Herba Hedyotidis Diffusae 20 grams, 15 grams, Pericarpium Citri Reticulatae Viride, Cortex Moutan 15 grams, 15 grams, Semen Persicae, the Radix Paeoniae Alba 15 grams, Carapax Trionycis 15 grams, Rhizoma Cyperi 15 grams, 15 grams, Poria, Cortex Phellodendri 15 grams, Ramulus Cinnamomi 10 grams, Radix Angelicae Sinensis 10 grams, Olibanum 10 grams, Myrrha 6 grams, 5 pieces, Fructus Jujubae, Rhizoma Coptidis 10 grams, Scorpio 6 grams, Scolopendra 10g, 3 grams, Radix Glycyrrhizae.
Preparation and instructions of taking: first by the Impurity removal of each crude drug, all medicines of receiving add water 500 milliliters in marmite, decoct half an hour, potion on the one, takes at twice.It within 30 days, is a course for the treatment of.
Pharmacological action:
Flos Sophorae (parched): have the effect such as vasoconstrictive, hemostasis, has unique therapeutic effect to hyperpietic.
Spica Prunellae: toil, cold.Enter liver, gallbladder meridian.Liver heat removing, eliminating stagnation.Control scrofula, goiter, acute mastitis, breast carcinoma, order pearl nyctalgia, photophobia is shed tears, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, acute icteric infectious hepatitis, metrorrhagia, leukorrhagia.
Herba Scutellariae Barbatae: heat clearing away, removing toxic substances, dissipating blood stasis, hemostasis, analgesic therapy.Control haematemesis, epistaxis, stranguria with blood, bloody dysentery, lung abscess, cancerous protuberance, traumatic injury knife injury, venom.
Herba Hedyotidis Diffusae: heat clearing away, dampness removing, removing toxic substances.Control dyspnea and cough due to lung-heat, tonsillitis.
Pericarpium Citri Reticulatae Viride: temperature, acrid in the mouth.Enter liver, gallbladder meridian.Soothing the liver dispelling the stagnated QI, eliminating stagnation expectorant.Control breast side of body gastralgia, hernia, food stagnation, swelling of the breast, nodule in the breast, chronic malaria addiction block Radix Angelicae Sinensis: sweet, acrid, warm.Enter the heart, liver, spleen channel.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia is heavy after bloody dysentery; Carbuncle skin ulcer is stolen, injury from falling down.
Cortex Moutan: heat clearing away, removing heat from blood, and blood, repercussive.Control the pathogenic heat attacking blood system in febrile diseases, send out speckle, infantile convulsion, tells, is defeated in battle, has blood in stool, hectic fever due to YIN-deficiency consumptive fever, and amenorrhea ， mass in the abdomen, carbuncle and ulcer, flutters damage.
Semen Persicae: bitter sweet is flat.Enter the heart, liver, large intestine channel.Blood stasis removing and clots absorbing, moisturizes laxation.Control amenorrhea ， mass in the abdomen, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.
The Radix Paeoniae Alba: picric acid is cool.Enter liver, spleen channel.Nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives antiperspirant. control the breast abdomen pain over the hypochondriac region, spontaneous sweating, fever due to yin deficiency.
Carapax Trionycis: salty is flat.Enter liver, spleen channel.Replenishing YIN and removing heat, suppressing the hyperactive liver to relieve the wind syndrome, hard masses softening and resolving.Control consumptive fever hectic fever due to YIN-deficiency, stirring of wind due to deficiency of YIN, malaria with general debility malaria with splenomegaly ， mass in the abdomen mass beside the umbilicus, amenorrhea menometrorrhagia, pediatric epilepsy scared.
Rhizoma Cyperi: pungent micro-hardship is sweet, flat.Enter liver, tri-jiao channel.To regulate the flow of vital energy resolving depression, pain relieving regulating menstruation.Treating the liver discomfort in the stomach, depression of QI, breast abdomen distending pain over the hypochondrium, phlegm retention feeling of fullness, menoxenia, bleeding not during menses.
Poria: sweet light is flat.Enter the heart, spleen, lung meridian.Eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Control dysuria, edema distension, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.
Cortex Phellodendri: bitter, cold.Enter kidney, urinary bladder channel.Heat clearing away, dampness, pathogenic fire purging removes steams, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, osteopyrexia and fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Ramulus Cinnamomi: Xin Gan, temperature.Enter bladder, the heart, lung meridian.Diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation.Control exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.
Radix Angelicae Sinensis: sweet, acrid, warm.Enter the heart, liver, spleen channel.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia is heavy after bloody dysentery; Carbuncle skin ulcer is stolen, injury from falling down.
Olibanum: regulating qi and activating blood, analgesic therapy, chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Myrrha: bitter, pungent is flat, nontoxic.Liver, spleen, the heart, kidney channel.Invigorate blood circulation analgesic therapy, detumescence and promoting granulation, cures mainly traumatic injury, incised wound, muscles and bones, all pains of trusted subordinate, lump in the abdomen, amenorrhea, ulcer sore pain, and skin infection does not close up after bursting for a long time.
Fructus Jujubae: sweet, temperature.Enter spleen, stomach warp.Spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid, adjusts battalion to defend, separates poison of drug.Control insufficiency of stomach lack of appetite, the weak loose stool of spleen, qi-blood-body fluid is not enough, disharmony of nutrient QI with defensive QI, severe palpitation.Married woman's stolen goods are hot-tempered.
Rhizoma Coptidis: bitter in the mouth, cold.Enter the heart, liver, stomach, large intestine channel.Pathogenic fire purging, dampness, removing toxic substances, parasite killing.Row pyretic toxicity when controlling, typhoid fever, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, and diarrhea of heat type is suffered from abdominal pain, and lung knot is pressed, and tells, is defeated in battle, hematochezia, quench one's thirst, infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.
Scorpio, Scolopendra: salty pungent, flat, poisonous.Meridian of Foot-JUE YIN.The two function is similar, has relieving spasm by subduing liver-wind, and effect of detoxicating and resolving stagnation of pathogens pain network pain relieving, can draw out pus by applying a plaster to the affected part by counteracting toxic substances, separate the stasis of blood and fall apart stagnant, open expectorant eliminating stagnation, broken hard detumescence.For intractable pain, there is obvious analgesic efficacy.
Cervical cancer belongs in the tcm clinical practice category such as " metrorrhagia ", " multicolored vaginal discharge ".Chinese medicine thinks that primary disease and punching are appointed relevant.Metrorrhagia, leukorrhagia are that punching is appointed deficient, and governor vessel mistake department, causes dai channel ill.Cervical cancer controlled by Chinese medicine can make up operative treatment, radiotherapy, chemotherapeutical deficiency, increases the chance of advanced cervical cancer patients's treatment.For the patient losing western medical treatment chance late period, adopt separately traditional Chinese medical herbal treatment effectively can improve the immunologic function of cervical cancer patient, improve body constitution, suppress to kill cancerous cell, soften and reduce tumor, increase the ability to bear of patient, recurrence and transfer can be prevented, increase the chance for the treatment of.
Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.
One, clinical observation
1, clinical data: the outpatient service and inpatient totally 78 examples that are selected from June, 20011 to 2012 year JIUYUE, wherein early cervical carcinoma 26 example.Age is 48-64 year, average 56.4 years old.
2, diagnostic criteria: the diagnosis of cervical cancer standard in " the Chinese common cancer diagnosis and treatment specification " compiled with China's Ministry of Public Health is for foundation.Clinical stages, all belongs to II phase, III phase, IV phase.Meet the standard of " Chinese common cancer diagnosis and treatment specification " and objective efficacy assessment standard, adopt WHO standard to evaluate.
3, Therapeutic Method: take medicine of the present invention, soak by water, takes at twice sooner or later.It within 1 month, is 1 course for the treatment of.
4, efficacy assessment standard: according to Ministry of Public Health " Chinese common cancer diagnosis and treatment specification " cervical cancer efficacy assessment standard, so that rear B ultrasonic or CT compare with treatment before patient treatment, carry out efficacy evaluation with complete incidence graph (CR), partial rcsponse (PR), stable (SD), progress (PD).
5, therapeutic outcome: complete incidence graph 62 example, partial rcsponse 7 example, stablizes 9 examples, progress 0 example.Effective percentage (CR+PR) is 88.5%, and coefficient of stabilization (CR+PR+SD) is 100%.There are 20 examples to cure (tumor all disappears, and follows up a case by regular visits to and does not recur for 1 year) in early stage 26 routine early cervical carcinomas simultaneously.
6, toxic and side effects analysis
In the 78 routine patients observed, only have 2 examples to occur stomach discomfort, 1 routine laxativeness, occur that the probability of side reaction is only 3.8% after taking Chinese medicine of the present invention, dispose side reaction through suiting the medicine to the illness and disappear, all the other are without any side effects.
In sum, the present invention is used for the treatment of the medicine of cervical cancer, through clinical trial, shows that it can effectively suppress cervical cancer to develop, improves patients symptomatic, sign, and without obvious toxic-side effects.
Two, model case
Case 1: Liu so-and-so, female, 38 years old, people from Hubei.This patient's hemorrhage of cervix, is diagnosed as cervical cancer through examination in hospital early stage.In western medical treatment and chemotherapy process, nausea and vomiting, inappetence, stops treatment.Take a course for the treatment of of Chinese medicine of the present invention, chest and abdomen swelling and pain alleviates, and vaginal hemorrhage reduces.Two courses for the treatment of of former side plus-minus following the service, clinical symptoms disappears substantially.Tumor disappearance on inspection.Follow up a case by regular visits to 1 year without recurrence.
Case 2: grandson, female, 41 years old, people from Shandong.More than patient's abnormal vaginal bleeding half a year, be diagnosed as by the section of certain Hospital Pathological Department: cervix uteri squama type cell carcinoma first phase.Patient refuses operation, by chemotherapy four the aggravation course for the treatment of, abnormal vaginal bleeding, costa sternales distension, sagging distention in the smaller abdomen pain, after taking two courses for the treatment of of Drug therapy of the present invention, there is not bleeding in cervix uteri, vaginal secretions is also normal to be alleviated again, after the course for the treatment of of continuing to take medicine, transference cure, recovers normal.
Case 3: solemn so-and-so, female, 48 years old, people from Xi'an.Patient, because of abnormal vaginal bleeding more than a year, has 3 scleromas, contact bleeding through certain examination in hospital cervix uteri is other.Be diagnosed as the cervical cancer second phase, after five courses for the treatment of of row radiotherapy, aggravation, vaginal hemorrhage amount is many, weak weak breath Mental fatigue, lower abdominal distention pain.Take two courses for the treatment of of treatment by Chinese herbs of the present invention, symptom takes a turn for the better, and sensation of oppression over the chest with shortness of breath alleviates, lower abdomen pain relief, and food of receiving increases, and two is just normal.Top plus-minus two courses for the treatment of of following the service, symptom disappears substantially.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine of cervical cancer, is made up of the crude drug of following weight: Flos Sophorae (parched) 20 grams, Spica Prunellae 20 grams, Herba Scutellariae Barbatae 20 grams, Herba Hedyotidis Diffusae 20 grams, 15 grams, Pericarpium Citri Reticulatae Viride, Cortex Moutan 15 grams, 15 grams, Semen Persicae, the Radix Paeoniae Alba 15 grams, Carapax Trionycis 15 grams, Rhizoma Cyperi 15 grams, 15 grams, Poria, Cortex Phellodendri 15 grams, Ramulus Cinnamomi 10 grams, Radix Angelicae Sinensis 10 grams, Olibanum 10 grams, Myrrha 6 grams, 5 pieces, Fructus Jujubae, Rhizoma Coptidis 10 grams, Scorpio 6 grams, Scolopendra 10g, 3 grams, Radix Glycyrrhizae.
Preparation and instructions of taking:
First by the Impurity removal of each crude drug, all medicines of receiving add water 500 milliliters in marmite, and decoct half an hour, potion on the one, takes at twice.It within 30 days, is a course for the treatment of.
Claims (1)
1. treat a Chinese medicine for cervical cancer, it is characterized in that, be made up of the crude drug of following weight: Flos Sophorae (parched) 20 grams, Spica Prunellae 20 grams, Herba Scutellariae Barbatae 20 grams, Herba Hedyotidis Diffusae 20 grams, 15 grams, Pericarpium Citri Reticulatae Viride, Cortex Moutan 15 grams, 15 grams, Semen Persicae, the Radix Paeoniae Alba 15 grams, Carapax Trionycis 15 grams, Rhizoma Cyperi 15 grams, 15 grams, Poria, Cortex Phellodendri 15 grams, Ramulus Cinnamomi 10 grams, Radix Angelicae Sinensis 10 grams, Olibanum 10 grams, Myrrha 6 grams, 5 pieces, Fructus Jujubae, Rhizoma Coptidis 10 grams, Scorpio 6 grams, Scolopendra 10g, 3 grams, Radix Glycyrrhizae; First by the Impurity removal of each crude drug, all medicines of receiving add water 500 milliliters in marmite, decoct half an hour.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310674302.2A CN103656041B (en) | 2013-12-11 | 2013-12-11 | A kind of Chinese medicine for the treatment of cervical cancer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310674302.2A CN103656041B (en) | 2013-12-11 | 2013-12-11 | A kind of Chinese medicine for the treatment of cervical cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103656041A CN103656041A (en) | 2014-03-26 |
| CN103656041B true CN103656041B (en) | 2016-04-20 |
Family
ID=50295600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310674302.2A Active CN103656041B (en) | 2013-12-11 | 2013-12-11 | A kind of Chinese medicine for the treatment of cervical cancer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103656041B (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104013925A (en) * | 2014-06-28 | 2014-09-03 | 黄翠萍 | Traditional Chinese medicine for treating cervical cancer |
| CN104027785A (en) * | 2014-06-28 | 2014-09-10 | 黄翠萍 | Traditional Chinese medicine honeyed pill for treating cervical cancer |
| CN104306632A (en) * | 2014-09-27 | 2015-01-28 | 张乔木 | An antitumor medicine and a preparing method thereof |
| CN104436063A (en) * | 2014-12-15 | 2015-03-25 | 鲁娟 | Traditional Chinese medicine for treating cervical cancer caused by damp heat and phlegm retention and preparation method of traditional Chinese medicine |
| CN104491719A (en) * | 2014-12-16 | 2015-04-08 | 牟慧芳 | Traditional Chinese medicine composition for treating cervical cancers |
| CN105250748A (en) * | 2015-10-08 | 2016-01-20 | 谭真 | Traditional Chinese medicine for treating cervical cancer and preparation method |
| CN105362685A (en) * | 2015-11-29 | 2016-03-02 | 四川聚豪生物科技有限公司 | Pill medicine with effective cervical cancer treatment function and method for preparing pill medicine |
| CN105853923A (en) * | 2016-05-17 | 2016-08-17 | 王德玉 | Pure traditional Chinese medicinal preparation for treating early-stage cervical carcinoma |
| CN106511864A (en) * | 2016-09-21 | 2017-03-22 | 深圳市得道中医馆管理有限责任公司 | Traditional Chinese medicine composition and preparation method and applications thereof in treatment of cervical carcinoma |
| CN106728762A (en) * | 2017-03-14 | 2017-05-31 | 贵州灿石正科信息咨询服务有限公司 | It is a kind of to treat Chinese medicine composition of cervical carcinoma and preparation method thereof |
| CN110227118A (en) * | 2018-03-05 | 2019-09-13 | 曾令元 | A kind of herbal composite that treating cervical carcinoma and preparation method |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1157737A (en) * | 1996-10-24 | 1997-08-27 | 张文善 | ''Shanzhiai'' oral dosage |
| CN101670071A (en) * | 2009-09-25 | 2010-03-17 | 卢速江 | Traditional Chinese medicine preparation for treating cancer and preparation method thereof |
| CN102716417A (en) * | 2012-06-15 | 2012-10-10 | 祁连明 | Traditional Chinese medicine preparation for treating gynaecopathia and preparation method of preparation |
| CN102772745A (en) * | 2012-08-21 | 2012-11-14 | 卢速江 | Chinese medicinal preparation for treating cancer and preparation method thereof |
-
2013
- 2013-12-11 CN CN201310674302.2A patent/CN103656041B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1157737A (en) * | 1996-10-24 | 1997-08-27 | 张文善 | ''Shanzhiai'' oral dosage |
| CN101670071A (en) * | 2009-09-25 | 2010-03-17 | 卢速江 | Traditional Chinese medicine preparation for treating cancer and preparation method thereof |
| CN102716417A (en) * | 2012-06-15 | 2012-10-10 | 祁连明 | Traditional Chinese medicine preparation for treating gynaecopathia and preparation method of preparation |
| CN102772745A (en) * | 2012-08-21 | 2012-11-14 | 卢速江 | Chinese medicinal preparation for treating cancer and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 近年来中医药治疗子宫颈癌的概况;李应存等;《甘肃中医》;19961231;第9卷(第1期);46-48 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103656041A (en) | 2014-03-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103656041B (en) | A kind of Chinese medicine for the treatment of cervical cancer | |
| CN103611094B (en) | A kind of medicine for the treatment of cervical cancer | |
| CN102671129B (en) | Traditional Chinese medicine compound for treating cervical cancer | |
| CN101700393B (en) | Traditional Chinese medicine composition for treating breast cancer | |
| CN103800622A (en) | Traditional Chinese medicament for treating prostatitis | |
| CN104383514A (en) | Traditional Chinese medicine for treating cervical cancer | |
| CN103751702B (en) | A kind of Chinese medicine for the treatment of breast carcinoma | |
| CN101569738B (en) | Plaster for treating mastitis, hyperplasia of mammary glands, breast lumps, hydrarthrosis, traumatic injury, preparation method and application thereof | |
| CN104013925A (en) | Traditional Chinese medicine for treating cervical cancer | |
| CN103656382A (en) | Traditional Chinese medicinal decoction for treating hemorrhoids | |
| CN102552753B (en) | Chinese medicinal composition for treating uterine fibroid | |
| CN103800842A (en) | Traditional Chinese medicine composition for treating carcinoma of urinary bladder | |
| CN103550709A (en) | Traditional Chinese medicine for treating chronic pelvic inflammation | |
| CN105832859A (en) | Medicine for treating lung cancer | |
| CN104013920A (en) | Traditional Chinese medicinal composition for treating gastric carcinoma | |
| CN103656525A (en) | Traditional Chinese medicinal composition for treating dysmenorrhea | |
| CN103585609A (en) | Traditional Chinese medicine composition for treating dysmenorrhea and preparation method thereof | |
| CN101618201B (en) | Medicine for curing vulvar leukoplakia | |
| CN104189878A (en) | Medicine for treating endometriosis | |
| CN104027785A (en) | Traditional Chinese medicine honeyed pill for treating cervical cancer | |
| CN102688453A (en) | Traditional Chinese medicine composite for treating breast cancer | |
| CN103285181B (en) | Traditional Chinese medicine composition for treating qi-stagnation and blood stasis type haemorrhoids | |
| CN104491719A (en) | Traditional Chinese medicine composition for treating cervical cancers | |
| CN102671124B (en) | Medicament for treating bilirubin calculus and preparation method thereof | |
| CN104436054A (en) | Traditional Chinese medicine for treating rectal cancer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhong Caiyun Inventor before: Zhang Chen |
|
| COR | Change of bibliographic data | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160324 Address after: 262500 Qingzhou maternal and child health care hospital, 2059 Linglong mountain road, Weifang, Shandong, Qingzhou Applicant after: Zhong Caiyun Address before: 250355 Changqing University of science and Technology Park, Ji'nan, University Road, No. 4655, No. Applicant before: Zhang Chen |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170605 Address after: The 9 group and the Yin Yang Zhen Feng Cun Qidong, Jiangsu city of Nantong province 226200 Patentee after: Qidong Feng Wu agricultural cooperatives Address before: 262500 Qingzhou maternal and child health care hospital, 2059 Linglong mountain road, Weifang, Shandong, Qingzhou Patentee before: Zhong Caiyun |