CN101618201B

CN101618201B - Medicine for curing vulvar leukoplakia

Info

Publication number: CN101618201B
Application number: CN2009100656518A
Authority: CN
Inventors: 辛保山
Original assignee: Individual
Current assignee: Individual
Priority date: 2009-08-05
Filing date: 2009-08-05
Publication date: 2012-02-29
Anticipated expiration: 2029-08-05
Also published as: CN101618201A

Abstract

The invention provides a medicine for curing vulvar leukoplakia. The medicine is prepared by the following raw traditional Chinese medical materials: gentian, bupleurum, fiveleaf akebia, alisma orientale, peach kernels, safflowers, red sage roots, barbed skullcap, angelica, peony roots, atractylodes, poria, radix rehmanniae, ginger and glycyrrhiza which are supplemented each other and jointly take the efficacy of clearing heat, promoting diuresis, promoting blood circulation by removing blood stasis, dispersing liver, nourishing blood and moistening dryness. The invention differentially cures the vulvar leukoplakia by traditional Chinese medical science, has ideal curing effect and achieves a curative ratio of 80 percent so that patients can recover.

Description

A kind of medicine of treating leukoplakia vulvae

Technical field

The invention belongs to technical field of Chinese medicines, relate to a kind of medicine of treating leukoplakia vulvae.

Background technology

Leukoplakia vulvae mainly is the proliferative lesion of a kind of mucosal epithelium or epidermis, is the localised leukasmus that betides on women's vulvar mucous membrane, generally is shown in the obese women after the menopause more than 40 years old.The primary disease cause of disease is unclear fully as yet, with some general factor as: diabetes, endocrine regulation, malnutrition, vitamin deficiency etc. are relevant, and leukoplakia vulvae also can be unclean by the part, the long-time stimulus of chronic inflammatory disease and vaginal secretions causes.Chinese medical discrimination thinks that this disease is how deficient by the internal organs QI and blood, and essence and blood does not fill, and is qi-blood disharmony, and pudendum loses in scholar and supports, and blood deficiency is then sought dry, wind syndrome due to blood-deficiency.Control suitable clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling, dispersing the stagnated live-QI to relieve the stagnation of QI, nourishing blood to expel wind, Runzao Zhiyang.

Summary of the invention

The medicine that the purpose of this invention is to provide a kind of effective treatment leukoplakia vulvae.

For realizing above-mentioned purpose; The present invention adopts following technical scheme: a kind of medicine of treating leukoplakia vulvae, process by following parts by weight of traditional Chinese medicines raw material: 4～8 parts in 11～19 parts of Radix Gentianae, 11～19 parts of Radix Bupleuri, 7～13 parts of Caulis Akebiaes, 7～13 parts of Rhizoma Alismatis, 7～13 parts in Semen Persicae, 7～13 parts on Flos Carthami, 11～19 parts of Radix Salviae Miltiorrhizaes, 14～26 parts of Herba Scutellariae Barbataes, 11～19 parts of Radix Angelicae Sinensis, 9～14 parts of the Radix Paeoniae Albas, 11～19 parts of the Rhizoma Atractylodis Macrocephalaes, 11～19 parts in Poria, 11～19 parts of Radix Rehmanniae, 7～13 parts in Rhizoma Zingiberis Recens and Radix Glycyrrhizae.

The parts by weight of said each raw material of Chinese medicine are: 6 parts in 15 parts of Radix Gentianae, 15 parts of Radix Bupleuri, 10 parts of Caulis Akebiaes, 10 parts of Rhizoma Alismatis, 10 parts in Semen Persicae, 10 parts on Flos Carthami, 15 parts of Radix Salviae Miltiorrhizaes, 20 parts of Herba Scutellariae Barbataes, 15 parts of Radix Angelicae Sinensis, 12 parts of the Radix Paeoniae Albas, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts in Poria, 15 parts of Radix Rehmanniae, 10 parts in Rhizoma Zingiberis Recens and Radix Glycyrrhizae.

Said medicine is a decoction, with each raw materials mix, adds raw material gross weight 5-7 decocting doubly then and boils 20-30 minute during preparation, the extracting juice that removes slag, one pair of every day, twice sooner or later.

Raw material of the present invention also can be processed pill, tablet or capsule by conventional method.

Among the present invention, Radix Gentianae, bitter in the mouth, cold in nature, go into liver, gallbladder meridian, heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire is used for damp and hot yellow cellulitis, swelling of the vulva pudendal pruritus, leukorrhagia, eczema pruritus, deafness, hypochondriac pain, bitter taste, convulsion with spasms.Radix Bupleuri, bitter in the mouth, cool in nature, go into liver, gallbladder meridian, reconciling superficies and interior is arranged, soothing the liver, the yang invigorating effect is controlled alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, diarrhea proctoptosis, menoxenia, uterine prolapse.Caulis Akebiae, bitter in the mouth, cool in nature, go into the heart, small intestinal, urinary bladder channel, pathogenic fire purging row water is arranged, the promoting blood circulation effect is controlled hot urination, stranguria with turbid discharge, edema, irritable feverish sensation in the chest, sore throat pharyngalgia, inflexible pain all over, women's amenorrhea, galactostasis.Rhizoma Alismatis, sweet in the mouth, cold in nature, go into kidney, urinary bladder channel, diuretic is arranged, eliminating dampness by diuresis, the effect that expels the heat-evil is controlled dysuria, edema distension, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria.Semen Persicae, bitter in the mouth, sweet, property is flat, goes into the heart, liver, large intestine channel, and blood stasis removing and clots absorbing is arranged, and moisturizes the laxation effect, controls amenorrhea ， mass in the abdomen, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.Flos Carthami, acrid in the mouth, warm in nature, go into the heart, Liver Channel, promoting blood circulation to restore menstrual flow is arranged, blood stasis removing pain relieving effect is controlled amenorrhea ， mass in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.Radix Salviae Miltiorrhizae, bitter in the mouth, tepor is gone into the heart, Liver Channel, and blood circulation promoting and blood stasis dispelling is arranged, calming heart and tranquilizing mind, evacuation of pus, the pain relieving effect is controlled angina pectoris, menoxenia, dysmenorrhea, amenorrhea, metrorrhagia leukorrhagia ， mass in the abdomen gathers, abdominal pain due to blood stasis, arthralgia, palpitation with fear sleeplessness, malignant boil toxic swelling.Herba Scutellariae Barbatae, acrid in the mouth, property is flat, and heat clearing away is arranged, detoxifcation, dissipating blood stasis, hemostasis, the analgesic therapy effect is controlled haematemesis, epistaxis, stranguria with blood, bloody dysentery, jaundice is had sore throat, and lung abscess is treated skin ulcer, scrofula, sore, cancerous protuberance, traumatic injury knife injury, venom.Radix Angelicae Sinensis, sweet in the mouth, suffering, warm in nature, go into the heart, liver, spleen channel, benefiting blood and regulating blood circulation is arranged, menstruction regulating and pain relieving is moisturized the laxation effect, controls menoxenia, and amenorrhea stomachache ， mass in the abdomen knot gathers metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; The dryness of the intestine dyschezia is heavy after the bloody dysentery; The carbuncle skin ulcer is stolen, injury from falling down.The Radix Paeoniae Alba, bitter in the mouth, acid, cool in nature, go into liver, spleen channel, nourishing blood to suppress the hyperactive liver is arranged, slow middle pain relieving, yin fluid astringing is received the antiperspirant effect, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.The Rhizoma Atractylodis Macrocephalae, bitter in the mouth, sweet, warm in nature, go into spleen, stomach warp, spleen reinforcing is arranged, stomach reinforcing, dampness and in, antiabortive effect is controlled deficient QI of the spleen and stomach, anorexia, the asthenia weak breath, deficiency-distension is had loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea is uneasy.Poria, sweet in the mouth, light, property is flat, goes into the heart, spleen, lung meridian, and eliminating dampness and diuresis is arranged, the strengthening the spleen stomach function regulating, the mind tranquilizing and the heart calming effect is controlled dysuria, the edema distension, the phlegm retention cough with dyspnea, the sound of vomiting of vomitting is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.Radix Rehmanniae, sweet in the mouth, hardship, cold in nature, go into the heart, liver, kidney channel, heat clearing away is arranged, removing heat from blood, the effect of YIN nourishing and the production of body fluid promoting is used for calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, the hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and sends out the speckle dermexanthesis.Rhizoma Zingiberis Recens, acrid in the mouth, warm in nature, go into lung, stomach, spleen channel, deliver, cold expelling, preventing or arresting vomiting is opened the expectorant effect, the wind and cold that cures cold, vomiting, phlegm retention is breathed with cough, and distension is had loose bowels; Separate the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poison.Radix Glycyrrhizae, sweet in the mouth, property is flat, goes into spleen, stomach, lung meridian, have and middle emergency, lung moistening, detoxifcation, the coordinating the actions of various ingredients in a prescription effect is controlled laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.

Raw material among the present invention complements each other, and Radix Gentianae, Herba Scutellariae Barbatae, the Rhizoma Atractylodis Macrocephalae, Radix Rehmanniae heat clearing away, dampness, are moisturized Semen Persicae, Flos Carthami, Radix Salviae Miltiorrhizae, Caulis Akebiae, Radix Angelicae Sinensis, Radix Paeoniae Alba blood circulation promoting and blood stasis dispelling, promoting blood circulation, blood-supplementing blood-nourishing; The soothing the liver yang invigorating of Radix Bupleuri, Poria, Rhizoma Alismatis eliminating dampness and diuresis, Radix Bupleuri, the Rhizoma Zingiberis Recens cold expelling, soothing the liver that induces sweat; The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription is played clearing away heat-damp and promoting diuresis altogether, blood circulation promoting and blood stasis dispelling, the soothing the liver effect that nourishes blood, moisturizes; The tcm syndrome differentiation and treatment leukoplakia vulvae, therapeutic effect is desirable, and cure rate reaches 80%; Generally can cure the 1-2 month, the patient is got well.

Through clinical treatment statistics, adopt Drug therapy female vulva leukoplakia disease of the present invention that 500 examples are arranged, wherein 400 examples are cured after taking medicine of the present invention fully, after recurrence; There are 50 examples to take the back effectively, but the recurrence sign is arranged; All the other 50 routine patients take DeGrain.Statistics cure rate 80%, effective percentage 90%, inefficiency 10%, inefficiency is low.

The specific embodiment

Embodiment 1: Radix Gentianae 11g, Radix Bupleuri 11g, Caulis Akebiae 7g, Rhizoma Alismatis 7g, Semen Persicae 7g, Flos Carthami 7g, Radix Salviae Miltiorrhizae 11g, Herba Scutellariae Barbatae 14g, Radix Angelicae Sinensis 11g, Radix Paeoniae Alba 9g, Rhizoma Atractylodis Macrocephalae 11g, Poria 11g, Radix Rehmanniae 11g, Rhizoma Zingiberis Recens 7g and Radix Glycyrrhizae 4g.

With each raw materials mix, the decocting that adds 6 times of raw material gross weights then boiled 25 minutes, the extracting juice that removes slag, one pair of every day, twice on the one during the preparation decoction.

Embodiment 2: 6 parts in 15 parts of Radix Gentianae, 15 parts of Radix Bupleuri, 10 parts of Caulis Akebiaes, 10 parts of Rhizoma Alismatis, 10 parts in Semen Persicae, 10 parts on Flos Carthami, 15 parts of Radix Salviae Miltiorrhizaes, 20 parts of Herba Scutellariae Barbataes, 15 parts of Radix Angelicae Sinensis, 12 parts of the Radix Paeoniae Albas, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts in Poria, 15 parts of Radix Rehmanniae, 10 parts in Rhizoma Zingiberis Recens and Radix Glycyrrhizae.

Process pill: can above each raw material of Chinese medicine be pulverized during preparation, add refined honey then and process honeyed pill, every ball 6g takes one time 1～2 ball, 2-3 time on the one.

Embodiment 3: 8 parts in 19 parts of Radix Gentianae, 19 parts of Radix Bupleuri, 13 parts of Caulis Akebiaes, 13 parts of Rhizoma Alismatis, 13 parts in Semen Persicae, 13 parts on Flos Carthami, 19 parts of Radix Salviae Miltiorrhizaes, 26 parts of Herba Scutellariae Barbataes, 19 parts of Radix Angelicae Sinensis, 14 parts of the Radix Paeoniae Albas, 19 parts of the Rhizoma Atractylodis Macrocephalaes, 19 parts in Poria, 19 parts of Radix Rehmanniae, 13 parts in Rhizoma Zingiberis Recens and Radix Glycyrrhizae.

Process capsule: with above each raw material of Chinese medicine pulverize, mixing, incapsulate and get final product, one time 2～4,2-3 time on the one.

Umber among the above embodiment is parts by weight.

Model case:

Case 1: Zhang, the woman, 45 years old, white macula appearred in pudendum before readme January; Pruritus, back white macula scope continue to enlarge, and find the wellability speckle that white macula thickens for white during prescription on individual diagnosis, and the border is clear; Meet the symptom of leukoplakia vulvae, be diagnosed as leukoplakia vulvae, take the medicine of the embodiment of the invention 2 and treat; Each ball, every day, each once took a healing in month sooner or later.

Case 2: hot certain, the woman, 50 years old, white macula appearred in the pudendum place before half a year; Hospital is diagnosed as leukoplakia vulvae, and the back adopts the hydrocortisone ointment that hospital opened to treat, but i.e. recurrence after stopping using, the patient is very painful; Went to a doctor in this place afterwards, takes the medicine of the embodiment of the invention 1 and treat, one pair of every day; One day twice, take after one month and to cure, after recurrence.

Case 3: Zheng, the woman, 53 years old, the situation of white macula appearred in pudendum the year before, but does not seek medical advice always, and back white macula enlarges and increases, and pruritus increases the weight of just to go to a doctor, and is diagnosed as leukoplakia vulvae, and indivedual white macula places chap, and small pieces are rotten to the corn, ulcer, and are comparatively serious.After take the embodiment of the invention 3 medicine treat, every day three times, each four, the one and a half months symptom of taking medicine continuously disappears basically, continued is taken two weeks and is carried out after treatment, thoroughly cures behind the two weeks, recurrence is paid a return visit in the back.

Claims

1. medicine of treating leukoplakia vulvae is characterized in that being processed by following parts by weight of traditional Chinese medicines raw material: 4～8 parts in 11～19 parts of Radix Gentianae, 11～19 parts of Radix Bupleuri, 7～13 parts of Caulis Akebiaes, 7～13 parts of Rhizoma Alismatis, 7～13 parts in Semen Persicae, 7～13 parts on Flos Carthami, 11～19 parts of Radix Salviae Miltiorrhizaes, 14～26 parts of Herba Scutellariae Barbataes, 11～19 parts of Radix Angelicae Sinensis, 9～14 parts of the Radix Paeoniae Albas, 11～19 parts of the Rhizoma Atractylodis Macrocephalaes, 11～19 parts in Poria, 11～19 parts of Radix Rehmanniae, 7～13 parts in Rhizoma Zingiberis Recens and Radix Glycyrrhizae.

2. the medicine of a treatment leukoplakia vulvae as claimed in claim 1, it is characterized in that: the parts by weight of said each raw material of Chinese medicine are: 6 parts in 15 parts of Radix Gentianae, 15 parts of Radix Bupleuri, 10 parts of Caulis Akebiaes, 10 parts of Rhizoma Alismatis, 10 parts in Semen Persicae, 10 parts on Flos Carthami, 15 parts of Radix Salviae Miltiorrhizaes, 20 parts of Herba Scutellariae Barbataes, 15 parts of Radix Angelicae Sinensis, 12 parts of the Radix Paeoniae Albas, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts in Poria, 15 parts of Radix Rehmanniae, 10 parts in Rhizoma Zingiberis Recens and Radix Glycyrrhizae.

3. the medicine of a treatment leukoplakia vulvae according to claim 1 or claim 2, it is characterized in that: said medicine is a decoction, with each raw materials mix, adds raw material gross weight 5-7 decocting doubly then and boils 20-30 minute during preparation, extracting juice removes slag.