CN103751570B - The migrainous Chinese medicine of a kind of orally taken for curing - Google Patents

The migrainous Chinese medicine of a kind of orally taken for curing Download PDF

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CN103751570B
CN103751570B CN201410049659.6A CN201410049659A CN103751570B CN 103751570 B CN103751570 B CN 103751570B CN 201410049659 A CN201410049659 A CN 201410049659A CN 103751570 B CN103751570 B CN 103751570B
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radix
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rhizoma
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王怀方
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Abstract

The invention discloses the migrainous Chinese medicine of a kind of orally taken for curing, belong to the field of Chinese medicines.It is made up of following raw material medicaments: the Radix Astragali, Pheretima, Rhizoma Chuanxiong, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, Poria, Radix Paeoniae Rubra, Semen Cassiae, the Radix Paeoniae Alba, Radix Rehmanniae Preparata, Radix Gentianae Macrophyllae, Spica Prunellae, Flos Carthami, Herba Schizonepetae, Flos Chrysanthemi, Semen Persicae, Herba Asari, Radix Bupleuri, Radix Codonopsis, Radix Angelicae Sinensis, Rhizoma Gastrodiae, the Radix Angelicae Dahuricae and Fructus Viticis.Its scheme of curing the disease of the present invention, based on activating QI to alleviate the depression, promoting blood circulation to remove obstruction in the collateral, the intestinal stasis relieving that reduces phlegm, wind-expelling pain-stopping, reaches the object improved blood circulation, reduce vascular resistance, microcirculation blood flow speed is accelerated, has instant effect, the advantages such as short treating period, expense are low.

Description

The migrainous Chinese medicine of a kind of orally taken for curing
Technical field
The present invention relates to the migrainous Chinese medicine of a kind of orally taken for curing, belong to the field of Chinese medicines.
Background technology
Migraine is a kind of pulsatile headache of recurrent exerbation, and be common chronic forms vascular illness, a lot of disease is in child and adolescence, the young and middle-aged phase reaches onset peak, and women is common, and men and women's Proportion of patients is about 1: 2 ~ 3, in crowd, prevalence is 5% ~ 10%, often has genetic background.The tendencys such as flash of light, blurred vision, numb limbs and tense tendons are often had before migraine, there is the pain of side head in few minutes to 1 hours, and aggravates gradually, until after there is Nausea and vomiting, sensation just has and taken a turn for the better, headache relief in peace and quiet, dark surrounds or after sleep.
The migrainous medicine of current treatment is a lot, and as pizotifen, ibuprofen etc., these medicines all have some curative effects substantially, but the frequent person that shows effect is as often taken analgesic, only cures the symptoms, not the disease, and also can bring many side effect.Use Chinese traditional treatment migraine, toxic and side effects is little, but the migrainous prescriptions of Chinese medicine of existing treatment exists long, the problem such as uncertain therapeutic efficacy the is cut course for the treatment of mostly.
Summary of the invention
The object of the invention is to the deficiency overcoming existing treatment, and provide a kind of orally taken for curing migrainous Chinese medicine, migraine treatment effect can be significantly improved.
Technical scheme of the present invention is: the migrainous Chinese medicine of a kind of orally taken for curing, it is characterized in that, be made up of the crude drug of following weight: Radix Astragali 18-22 gram, Pheretima 12-18 gram, Rhizoma Chuanxiong 12-18 gram, Rhizoma Atractylodis Macrocephalae 8-12 gram, Radix Saposhnikoviae 8-12 gram, Poria 8-12 gram, Radix Paeoniae Rubra 8-12 gram, Semen Cassiae 8-12 gram, Radix Paeoniae Alba 8-12 gram, Radix Rehmanniae Preparata 8-12 gram, Radix Gentianae Macrophyllae 8-12 gram, Spica Prunellae 8-12 gram, Flos Carthami 8-12 gram, Herba Schizonepetae 5-8 gram, Flos Chrysanthemi 5-8 gram, Semen Persicae 5-8 gram, Herba Asari 1-3 gram, Radix Bupleuri 12-18 gram, Radix Codonopsis 12-18 gram, Radix Angelicae Sinensis 12-18 gram, Rhizoma Gastrodiae 12-18 gram, Radix Angelicae Dahuricae 8-12 gram, Fructus Viticis 5-10 gram.
Optimum ratio: the Radix Astragali 20 grams, Pheretima 15 grams, Rhizoma Chuanxiong 15 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, Radix Saposhnikoviae 10 grams, 10 grams, Poria, Radix Paeoniae Rubra 10 grams, Semen Cassiae 10 grams, the Radix Paeoniae Alba 10 grams, Radix Rehmanniae Preparata 10 grams, Radix Gentianae Macrophyllae 10 grams, Spica Prunellae 10 grams, 10 grams, Flos Carthami, Herba Schizonepetae 6 grams, Flos Chrysanthemi 6 grams, 6 grams, Semen Persicae, Herba Asari 2 grams, Radix Bupleuri 15 grams, Radix Codonopsis 15 grams, Radix Angelicae Sinensis 15 grams, 15 grams, Rhizoma Gastrodiae, the Radix Angelicae Dahuricae 10 grams, Fructus Viticis 8 grams.
Preparation and instructions of taking: soak by water, take at twice sooner or later.It within seven days, is a course for the treatment of.
Pharmacological action:
The Radix Astragali: warm in nature, sweet in the mouth.Tonifying Qi and lifting yang, benefit defends consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, diuretic detumescent.Cure mainly weakness of the spleen and stomach, lack of appetite asthenia, deficiency of vital energy blood prostration, exterior deficiency spontaneous perspiration, night sweat.
Pheretima: heat clearing away, suppressing the hyperactive liver, Zhichuan, dredging collateral.Control high fanatical hot-tempered, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, apoplexy and hemiplegia, pants, sore throat, arthralgia, bleeding from the gum, urinary obstruction, scrofula.
Rhizoma Chuanxiong: acrid in the mouth, temperature.Enter liver, gallbladder meridian.Activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
The Rhizoma Atractylodis Macrocephalae: bitter sweet, temperature.Enter spleen, stomach warp.Spleen reinforcing, stomach reinforcing, dampness, and in, antiabortive.Control deficient QI of the spleen and stomach, anorexia, asthenia weak breath, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizzy, spontaneous perspiration, and nausea is uneasy.
Radix Saposhnikoviae: Xin Gan, temperature.Enter bladder, lung, spleen channel.Deliver and dispel the wind, victory is wet, pain relieving.Control affection of exogenous wind-cold, headache, dizzy, stiffness of the nape, anemofrigid-damp arthralgia, joint is ached.
Poria: sweet light is flat.Enter the heart, spleen, lung meridian.Eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Control dysuria, edema distension, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.
Radix Paeoniae Rubra: bitter, is slightly cold.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea , mass in the abdomen is suffered from abdominal pain, injury from falling down, carbuncle skin infection.
Semen Cassiae: bitter sweet, cool.Enter liver, kidney channel.Have liver heat removing, improving eyesight, dispel the wind, effect of relieving constipation.Control the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation.
The Radix Paeoniae Alba: picric acid is cool.Enter liver, spleen channel.Nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives antiperspirant.Control the breast abdomen pain over the hypochondriac region, spontaneous sweating, fever due to yin deficiency.
Radix Rehmanniae Preparata: both kind YIN nourishing of enriching blood, again can vital essence replenishing and marrow benifiting, cures mainly the disease that all blood deficiency the moon lose oligospermia.Major function nourishing the blood and yin, vital essence replenishing and marrow benifiting, for blood deficiency and yellow complexion, dizzy, cardiopalmus.
Radix Gentianae Macrophyllae: expelling wind and removing dampness, and blood relaxing muscles and tendons, clearing away heat and promoting diuresis.Dispelling the wind and dampness pathogens arthralgia pain; Muscles and bones contracture, jaundice, has blood in stool, osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.
Spica Prunellae: toil, cold.Enter liver, gallbladder meridian.Liver heat removing, eliminating stagnation.Control scrofula, goiter, acute mastitis, breast carcinoma, order pearl nyctalgia, photophobia is shed tears, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, acute icteric infectious hepatitis, metrorrhagia, leukorrhagia.
Flos Carthami: pungent, temperature.Enter the heart, Liver Channel.Promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving.Control amenorrhea , mass in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.
Herba Schizonepetae: pungent, temperature.Enter lung, Liver Channel.Deliver, dispel the wind, treating blood disorders; Parch to black stops blooding.Cure cold heating, headache, laryngopharynx swelling and pain, apoplexy locked mouth, and spit blood, epistaxis, has blood in stool; Metrorrhagia, puerperal blood faints; Carbuncle, skin ulcer scabies, scrofula.
Flos Chrysanthemi: sweetness and bitterness is cool.Enter lung, Liver Channel.Dispelling wind, heat clearing away, improving eyesight, removing toxic substances.Control headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.
Semen Persicae: bitter sweet is flat.Enter the heart, liver, large intestine channel.Blood stasis removing and clots absorbing, moisturizes laxation.Control amenorrhea , mass in the abdomen, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.
Herba Asari: pungent, temperature.Enter lung, kidney channel.There is the effects such as expelling cold and relieving exterior syndrome, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, anti-inflammatory analgetic, heat-clearing and toxic substances removing. control air-cooled headache, nasal sinusitis, laugh somebody to scorn, rheumatic arthralgia.
Radix Bupleuri: pungent, micro-hardship, to be slightly cold; Return liver, gallbladder meridian.Induce sweat and bring down a fever, soothing liver-QI for relieving depression, elevate a turnable ladder yang-energy.This product is dredged to reach and kind be thoroughly longer than and discongest stagnant heat in the liver and gall, again can depressed liver-energy dispersing and QI regulating, pain over the hypochondriac region key medicine caused by treatment stagnant heat in the liver and gall, stagnation of QI due to depression of the liver.
Radix Codonopsis: sweet is flat.Start with, meridian of Foot-TAI YIN edema caused by disorder of QI.Invigorating the spleen and replenishing QI, promotes the production of body fluid, and nourishes blood.The empty asthenia of body for deficiency of QI in middle-JIAO, weakness of the spleen and stomach, deficiency of both QI and blood, controls fatigue and lack of strength, lung qi virtual loss.Control lack of appetite, thirsty, chronic diarrhea, proctoptosis.And the two shallow complexion of losing of QI and blood, dizzy cardiopalmus etc.
Radix Angelicae Sinensis: sweet, acrid, warm.Enter the heart, liver, spleen channel.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Control menoxenia, amenorrhea stomachache , mass in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia is heavy after bloody dysentery; Carbuncle skin ulcer is stolen, injury from falling down.
Rhizoma Gastrodiae: acrid in the mouth, temperature.Enter Liver Channel.Endogenous wind stopping, arresting convulsion. control dizzy pupil, wind syndrome of head is had a headache, numb limbs and tense tendons, hemiplegia.
The Radix Angelicae Dahuricae: pungent, temperature.Enter lung, thigh, stomach warp.Dispel the wind, dampness, detumescence, pain relieving.Control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.
Fructus Viticis: dispelling wind and heat pathogens, the clear sharp head.Control anemopyretic cold, headache, toothache, acute conjunctivitis, arthralgia chiefly caused by damp pathogen contracture.
The traditional Chinese medical science is thought, headache, the reason of migrainous generation is deficient qi and blood, blood stasis blocking, irritability is not smooth, the reasons such as excessive rising of liver-YANG cause the obstruction of head passages through which vital energy circulates to cause, for the etiology and pathogenesis of primary disease, the guiding theory of its scheme of curing the disease should from activating QI to alleviate the depression, promoting blood circulation to remove obstruction in the collateral, reduce phlegm intestinal stasis relieving, wind-expelling pain-stopping is main, reach and improve blood circulation, reduce vascular resistance, make the object that microcirculation blood flow speed is accelerated, there is instant effect, short treating period, the advantages such as expense is low, make headache, migrainous attack times gradually reduces, until stop, thus reach and fundamentally really cure headache, migrainous object.
Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.
1, clinical data: be selected from patient's totally 136 examples year March in January, 2012 to 2013 with complete data.Be divided into two groups at random, treatment group 68 example, matched group 68 example.Treatment group adopts treatment by Chinese herbs of the present invention, and matched group adopts the treatment of pizotifen, ibuprofen, continuously treatment 3 months.
2, diagnostic criteria:
(1) intermittent recurrent exerbation, start-stop is unexpected, and the intermission, the course of disease was longer as ordinary person.
(2) normal onset is in adolescence, and women falls ill in the majority.
(3) based on pulsatile headache when showing effect, also can be distending pain.
(4) side headache is main, also can be full headache.
(5) to have before Headache attacks or without premonitory symptom or simultaneous phenomenons such as sense of vision, sensualness, mobility, spiritualities, but during outbreak majority all with the significantly autonomic nerve symptom such as Nausea and vomiting.
(6) family has or without migrainous same trouble patient.
(7) factor such as some diet, menstruation, anxious state of mind, overwork can be brought out, compressing common carotid artery, superficial temporal artery, supraorbital artery or have a rest in short-term, sleeping to make headache alleviate.
(8) striped detests test mostly to be positive, and EEG (electrocardiogram) examination is even to be had slight or moderate is abnormal, asymmetric through cranium color Doppler visible bilateral cerebral blood flow speed, Brian Imaging (comprising angiography) and other auxiliary examinations all without exception.
3. efficacy assessment standard:
This efficacy assessment standard formulates with reference to according to " disease of tcm Standardization of diagnosis and curative effect ".
1. fully recover: migraine and related symptoms all disappear, and do not affect activity and work, follow up a case by regular visits to 3 months without recurrence;
2. effective: migraine and related symptoms thereof disappear substantially, after treatment, symptom obviously alleviates, and does not affect daily life and work;
3. effective: related symptoms and sign are improved, but unstable condition, there is recurrence after drug withdrawal;
4. invalid: clinical symptoms and sign unchanged or instead to increase the weight of.
4. therapeutic outcome: two groups of therapeutic outcomes are as shown in table 1:
Treatment group compares with matched group total effective rate, utilizes this kind of migrainous Chinese medicine composition total effective rate of orally taken for curing up to 97.0%, far above matched group 64.7% total effective rate, and difference highly significant, and have no side effect through this medicine of clinical observation.
Model case
Example one: flood so-and-so, female, 16 years old.Patient often had a headache over the past two years, and on the right side of during outbreak, the huge pain of head unbearably, started to be show effect 1-2 time every month, each headache continues several hours, but constantly serious along with the state of an illness, existing headache almost every day, oral pain alleviating class medicine, poor effect, after taking a course for the treatment of of Chinese medicine of the present invention, headache syndromes is clearly better, and after the after treatment of three courses for the treatment of, symptom is eliminated completely, thorough disengaging Drug therapy, follows up a case by regular visits to without rebound phenomenon.Example two: Dong so-and-so, man, 38 years old, patient starts headache companion nausea and vomiting the year before, eats analgesic symptom and alleviates, aggravation afterwards, pain time lengthens, and frequency increases, and time serious, almost every day all has a headache, and pain degree aggravation, took treatment by Chinese herbs of the present invention upon somebody's introduction afterwards, the same day symptom of taking medicine alleviates, take medicine seven days afterwards have a headache number of times reduce, pain degree alleviates, and continues medication treatment and fully recovers after one month, follow up a case by regular visits to and do not recur so far.
Example three: look into so-and-so, 45 years old, female.The frequent cephalic pain of patient, based on forehead and sun district, right side, ate a lot of Chinese medicine and western medicine and was showed no effect.After taking a course for the treatment of of this kind of orally taken for curing migrainous Chinese medicine, patient has a headache and obviously alleviates, and symptom is progressively alleviated, then through the after treatment of two courses for the treatment of, clinical symptoms disappears completely, follows up a case by regular visits to and does not recur so far.
Detailed description of the invention
Embodiment 1
Proportioning: the Radix Astragali 20 grams, Pheretima 15 grams, Rhizoma Chuanxiong 15 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, Radix Saposhnikoviae 10 grams, 10 grams, Poria, Radix Paeoniae Rubra 10 grams, Semen Cassiae 10 grams, the Radix Paeoniae Alba 10 grams, Radix Rehmanniae Preparata 10 grams, Radix Gentianae Macrophyllae 10 grams, Spica Prunellae 10 grams, 10 grams, Flos Carthami, Herba Schizonepetae 6 grams, Flos Chrysanthemi 6 grams, 6 grams, Semen Persicae, Herba Asari 2 grams, Radix Bupleuri 15 grams, Radix Codonopsis 15 grams, Radix Angelicae Sinensis 15 grams, 15 grams, Rhizoma Gastrodiae, the Radix Angelicae Dahuricae 10 grams, Fructus Viticis 8 grams.
Preparation and instructions of taking: raw material is mixed in marmite, adds water and soak in right amount; First intense fire is fried boiling, then with half an hour at a simmer, leaches medicinal liquid, adds water and again decoct half an hour in right amount, then leach medicinal liquid in medicinal residues.Twice medicinal liquid mixes, cools completely, and respectively at half an hour before breakfast, within after supper two hours, takes.It within seven days, is a course for the treatment of.
Embodiment 2
Proportioning: the Radix Astragali 18 grams, Pheretima 12 grams, Rhizoma Chuanxiong 12 grams, the Rhizoma Atractylodis Macrocephalae 8 grams, Radix Saposhnikoviae 8 grams, 8 grams, Poria, Radix Paeoniae Rubra 8 grams, Semen Cassiae 8 grams, the Radix Paeoniae Alba 8 grams, Radix Rehmanniae Preparata 8 grams, Radix Gentianae Macrophyllae 8 grams, Spica Prunellae 8 grams, 8 grams, Flos Carthami, Herba Schizonepetae 5 grams, Flos Chrysanthemi 5 grams, 5 grams, Semen Persicae, Herba Asari 1 gram, Radix Bupleuri 12 grams, Radix Codonopsis 12 grams, Radix Angelicae Sinensis 12 grams, 12 grams, Rhizoma Gastrodiae, the Radix Angelicae Dahuricae 8 grams, Fructus Viticis 5 grams.
Preparation and instructions of taking: with embodiment 1.
Embodiment 3
Proportioning: the Radix Astragali 22 grams, Pheretima 18 grams, Rhizoma Chuanxiong 18 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Radix Saposhnikoviae 12 grams, 12 grams, Poria, Radix Paeoniae Rubra 12 grams, Semen Cassiae 12 grams, the Radix Paeoniae Alba 12 grams, Radix Rehmanniae Preparata 12 grams, Radix Gentianae Macrophyllae 12 grams, Spica Prunellae 12 grams, 12 grams, Flos Carthami, Herba Schizonepetae 8 grams, Flos Chrysanthemi 8 grams, 8 grams, Semen Persicae, Herba Asari 3 grams, Radix Bupleuri 18 grams, Radix Codonopsis 18 grams, Radix Angelicae Sinensis 18 grams, 18 grams, Rhizoma Gastrodiae, the Radix Angelicae Dahuricae 12 grams, Fructus Viticis 10 grams.
Preparation and instructions of taking: with embodiment 1.

Claims (2)

1. the migrainous Chinese medicine of orally taken for curing, it is characterized in that, be made up of the crude drug of following weight: Radix Astragali 18-22 gram, Pheretima 12-18 gram, Rhizoma Chuanxiong 12-18 gram, Rhizoma Atractylodis Macrocephalae 8-12 gram, Radix Saposhnikoviae 8-12 gram, Poria 8-12 gram, Radix Paeoniae Rubra 8-12 gram, Semen Cassiae 8-12 gram, Radix Paeoniae Alba 8-12 gram, Radix Rehmanniae Preparata 8-12 gram, Radix Gentianae Macrophyllae 8-12 gram, Spica Prunellae 8-12 gram, Flos Carthami 8-12 gram, Herba Schizonepetae 5-8 gram, Flos Chrysanthemi 5-8 gram, Semen Persicae 5-8 gram, Herba Asari 1-3 gram, Radix Bupleuri 12-18 gram, Radix Codonopsis 12-18 gram, Radix Angelicae Sinensis 12-18 gram, Rhizoma Gastrodiae 12-18 gram, Radix Angelicae Dahuricae 8-12 gram, Fructus Viticis 5-10 gram.
2. the migrainous Chinese medicine of a kind of orally taken for curing as claimed in claim 1, it is characterized in that, be made up of the crude drug of following weight: the Radix Astragali 20 grams, Pheretima 15 grams, Rhizoma Chuanxiong 15 grams, the Rhizoma Atractylodis Macrocephalae 10 grams, Radix Saposhnikoviae 10 grams, 10 grams, Poria, Radix Paeoniae Rubra 10 grams, Semen Cassiae 10 grams, the Radix Paeoniae Alba 10 grams, Radix Rehmanniae Preparata 10 grams, Radix Gentianae Macrophyllae 10 grams, Spica Prunellae 10 grams, 10 grams, Flos Carthami, Herba Schizonepetae 6 grams, Flos Chrysanthemi 6 grams, 6 grams, Semen Persicae, Herba Asari 2 grams, Radix Bupleuri 15 grams, Radix Codonopsis 15 grams, Radix Angelicae Sinensis 15 grams, 15 grams, Rhizoma Gastrodiae, the Radix Angelicae Dahuricae 10 grams, Fructus Viticis 8 grams.
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