CN103550696A - Medicine for treating lung cancer - Google Patents
Medicine for treating lung cancer Download PDFInfo
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Abstract
The invention discloses a medicine for treating lung cancer. The medicine is prepared from the following crude medicines: ginseng, lucid ganoderma, codonopsis pilosula, fruit of Chinese magnoliavine, selfheal, oldenlandia diffusa, houttuynia cordata, java brucea fruit, seed of cowherb, astragalus membranaceus, medlar, glossy privet fruit, yam, gorgon euryale seed, bighead atractylodes rhizome, radix glehniae, turtle shell, radix polygonati officinalis, dendrobe, vietnamese sophora root, radix curcumae, common hogfenneI root, cortex lycii radicis, trichosanthes kirilowii maxim, tabasheer, root of common peony, angelica, Indian iphigenia bulb, suberect spatholobus stem, platycodon grandiflorum, curcuma zedoary, ligusticum wallichii and liquorice. The medicine, in treating lung cancer, can achieve a total effective rate of 91%.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of pulmonary carcinoma, belong to technical field of Chinese medicines.
Background technology
Pulmonary carcinoma is that M & M growth is the fastest, and population health and life are threatened to one of maximum malignant tumor.Over nearly 50 years, many countries all report that the M & M of pulmonary carcinoma all obviously increases, and male lung cancer M & M all accounts for first of all malignant tumor, and women's sickness rate accounts for second, and mortality rate accounts for second.The cause of disease of pulmonary carcinoma is still not exclusively clear and definite so far, and great mass of data shows, long-term a large amount of smoking and pulmonary carcinoma have a very close relationship.
The treatment means of pulmonary carcinoma has operation, radiotherapy, Drug therapy at present, and the Comprehensive Treatment of above-mentioned therapy.In Drug therapy, Chinese medicine, because lasting medicine, side effect are little, becomes patient's first-selection, take to alleviate patient's misery, extend its life, improve its quality of life as object, and on market, this type of Chinese medicine is many, but ubiquity uncertain therapeutic efficacy cuts, the problem that effective percentage is low.
Summary of the invention
The present invention has overcome above-mentioned the deficiencies in the prior art, and a kind of medicine for the treatment of pulmonary carcinoma is provided, and this medicine has good therapeutic effect to pulmonary carcinoma.
Technical scheme of the present invention is: a kind of medicine for the treatment of pulmonary carcinoma, it is characterized in that, crude drug by following weight is made: Radix Ginseng 10 g, Ganoderma 10 g, Radix Codonopsis 15 g, Fructus Schisandrae Chinensis 10 g, Spica Prunellae 10 g, Herba Hedyotidis Diffusae 15 g, Herba Houttuyniae 12 g, Fructus Bruceae 12 g, Semen Vaccariae 10 g, the Radix Astragali 10 g, Fructus Lycii 15 g, Fructus Ligustri Lucidi 20 g, Rhizoma Dioscoreae 18 g, Semen Euryales 15 g, the Rhizoma Atractylodis Macrocephalae 15 g, Radix Glehniae 15 g, Carapax Trionycis 20 g, Rhizoma Polygonati Odorati 18 g, Herba Dendrobii 15 g, Radix Sophorae Tonkinensis 10 g, Radix Curcumae 15 g, Radix Peucedani 12 g, Cortex Lycii 12 g, Fructus Trichosanthis 10 g, Concretio Silicea Bambusae 8 g, Radix Paeoniae Rubra 8 g, Radix Angelicae Sinensis 10g, Pseudobulbus Cremastrae Seu Pleiones 12g, Caulis Spatholobi 10g, Radix Platycodonis 10g, Rhizoma Curcumae 12g, Rhizoma Chuanxiong 15g and Radix Glycyrrhizae 5g.
Preparation and instructions of taking: decocting boils, take at twice sooner or later, within 1 month, is 1 course for the treatment of.
Each herbal pharmacology effect:
Radix Ginseng: sweet, micro-hardship, flat.Return spleen, lung, heart channel.Function with cure mainly: strongly invigorating primordial QI, multiple arteries and veins is admittedly de-, invigorating the spleen to benefit the lung, promotes the production of body fluid, and calms the nerves.For weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, prolonged illness weakness with emaciation, palpitation with fear insomnia, sexual impotence cold womb; Heart failure, cardiogenic shock.
Ganoderma: sweet, flat.GUIXIN, lung, liver, kidney channel.There is the effect of antitumor and protecting liver and detoxication.
Radix Codonopsis: sweet, flat.Return spleen, lung meridian.Spleen invigorating lung benefiting, nourishing blood to promote the production of body fluid.For deficiency of both the splenic and pulmonary QI, lack of appetite asthenia, cough dyspnea due to deficiency, insufficiency of vital energy and blood, shallow complexion, shortness of breath and palpitation, Tianjin wound is thirsty, and interior-heat is quenched one's thirst.
Fructus Schisandrae Chinensis: sour, sweet, temperature.Lung, the heart, kidney channel.Restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, palpitation and insomnia.
Spica Prunellae: pungent, bitter, cold.Return liver, gallbladder meridian.Function with cure mainly: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, and goiter, acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Herba Hedyotidis Diffusae: bitter sweet, cold.Nontoxic, enter heart channel, Liver Channel, spleen channel.Effect: heat-clearing and toxic substances removing; Dampness removing.Cure mainly: dyspnea and cough due to lung-heat; Laryngopharynx swelling and pain; Intestinal carbuncle; Furuncle and phyma skin infection; Venom; The puckery pain of pyretic stranguria; Edema; Dysentery; Intestinal is scorching; Jaundice due to damp-heat; Be good at treatment kinds cancer.
Herba Houttuyniae: heat-clearing and toxic substances removing; Removing pus and relieving carbuncle; Inducing diuresis for treating stranguria syndrome.Cure mainly: the main lung abscess vomiting pus of pyretic stranguria; Expectorant dyspnea of heat type is coughed; Larynx; Hematodiarrhoea; Carbuncle sore tumefacting virus.Effect: heat-clearing and toxic substances removing, inducing diuresis to remove edema.Control pneumonia, malaria, edema, gonorrhea, leucorrhea, carbuncle, hemorrhoid, proctoptosis, eczema, tinea alba, scabies etc.
Fructus Bruceae: hardship, cold; Slightly poisonous.Return large intestine, Liver Channel.Function with cure mainly: heat-clearing and toxic substances removing, preventing the attack (or recurrence) of malaria, dysentery relieving, corrosion wart.For dysentery, malaria; External treatment wart, clavus.
Pollen Typhae: sweet, flat.Return liver, pericardium channel.Function with cure mainly: hemostasis, blood stasis dispelling, treating stranguria.For spitting blood, epistaxis, spitting of blood, metrorrhagia, traumatic hemorrhage, amenorrhea dysmenorrhea, gastral cavity ventral spine pain, tumbling and swelling, blood strangury and dry pain.
Semen Vaccariae: hardship, flat.Return liver, stomach warp.Function with cure mainly: promoting blood circulation to restore menstrual flow, stimulating milk secretion detumescence.For agalactia, amenorrhea, dysmenorrhea, acute mastitis swells and ache.
The Radix Astragali: sweet, temperature.Return lung, spleen channel.Function with cure mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Fructus Lycii: sweet in the mouth; Property is put down.Return Liver Channel; Kidney channel; Lung meridian.Nourishing the liver; Nourishing kidney; Lung moistening.Caused by liver and kidney deficiency; Have a dizzy spell; Visual unclear; Soreness of the waist and knees; Impotence and seminal emission; Cough due to consumptive disease; The taking fluids profusely of quenching one's thirst.
Fructus Ligustri Lucidi: sweet, bitter, cold.Return liver, kidney channel.Nourishing the liver and kidney, improving eyesight black hair.For the hepatic and renal YIN deficiency, vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision, interior-heat is quenched one's thirst, osteopyrexia and fever.
Rhizoma Dioscoreae: there is spleen reinforcing nourishing the stomach, the function of the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung breath with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat quench one's thirst.Rhizoma dioscoreae (parched) spleen reinforcing stomach invigorating, for insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, leukorrhagia.
Semen Euryales: sweet in the mouth, puckery, property is flat.Return spleen, kidney channel.There is supplementing the kidney to control the nocturnal, spleen reinforcing antidiarrheal, the function of damp eliminating leukorrhagia stopping.Raw moral character is flat, puckery and not stagnant, spleen reinforcing kidney and hold concurrently can damp eliminating.Be usually used in nebulousurine, leukorrhagia, seminal emission, incontinence of urine, the turbid damp person that holds concurrently is especially suitable.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, temperature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Radix Glehniae: sweet, micro-hardship, is slightly cold.Attach to the lung and stomach meridians.Nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.For lung-heat type cough, chronic cough expectorant blood, deficiency of stomach-Yin, calentura Tianjin wound, dry throat and mouth.
Carapax Trionycis: salty, be slightly cold.Return liver, kidney channel.Nourishing YIN for suppressing the hyperactive YANG, brings down a fever except steaming, hard masses softening and resolving.For fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, hyperactivity of YANG due to deficiency of YIN, has a dizzy spell, stirring-up of pathogenic wind in the interior resulting from deficiency.
Rhizoma Polygonati Odorati: sweet in the mouth, property is flat.Return lung; Stomach warp.Effect with cure mainly: nourishing YIN and moistening the lung; Nourishing the stomach to promote the production of body fluid.Cough caused by dryness; Chronic cough; The dry throat and mouth of the cloudy liquid consumption of calentura wound; Interior-heat is quenched one's thirst; Deficiency of YIN diseases caused by exogenous pathogenic factor; Dizzy dizzy; Muscle arteries and veins spasm and pain.
Herba Dendrobii: sweet, be slightly cold.Return stomach, kidney channel.Function with cure mainly: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.For calentura Tianjin wound, xerostomia excessive thirst, deficiency of stomach-Yin, lack of appetite is retched, and deficiency-heat is not moved back after being ill, hyperactivity of fire caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, poor vision, muscles and bones flaccidity is soft.
Radix Sophorae Tonkinensis: hardship, cold; Poisonous.Attach to the lung and stomach meridians.Heat-clearing and toxic substances removing, detumescence sore-throat relieving.For fire-toxin, pent up disease.
Radix Curcumae: pungent, bitter, cold.Return liver, the heart, lung meridian.Promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice.For the twinge of the breast side of body, obstruction of qi in the chest and cardialgia.
Radix Peucedani: bitter, pungent, be slightly cold.Return lung meridian.Lowering the adverse-rising QI to resolve phlegm, loose wind heat clearing away.Full for expectorant dyspnea of heat type, cough up phlegm yellow thick, cough due to pathogenic wind-heat's abundant expectoration.
Cortex Lycii: sweet, cold.Return lung, liver, kidney channel.Removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing.For cloudy Virtual hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis, interior-heat is quenched one's thirst.
The Rhizoma Anemarrhenae: bitter, sweet, cold.Return lung, stomach, kidney channel.Clearing away heat-fire is nourshing Yin and drynsessmoistening prescription.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Fructus Trichosanthis: sweet, micro-hardship, cold.Return lung, stomach, large intestine channel.Clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes laxation.For cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, acute appendicitis, constipation.
Concretio Silicea Bambusae: sweet, cold.GUIXIN, Liver Channel.Clear heat and eliminate phlegm, cool heart arresting convulsion.For calentura coma, middle wind-phlegm fan, the hot infantile convulsion of children's's expectorant, tic, night cry.
Radix Paeoniae Rubra: hardship, is slightly cold.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.For heat, enter nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, mass in the abdomen stomachache, injury from falling down, carbuncle skin infection etc.
Fructus Jujubae: sweet, temperature.Return spleen, stomach, heart channel.Invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.For spleen Virtual lack of appetite, weak loose stool, woman hysteria.
Radix Angelicae Sinensis: sweet, acrid, warm.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.
Pseudobulbus Cremastrae Seu Pleiones: sweet, micro-pungent, cold.Enter liver, spleen channel.Detumescence, eliminating stagnation, reduces phlegm, removing toxic substances.Control carbuncle furuncle swollen, scrofula, sore throat swells and ache, Serpentis, worm, mad dog wound.
Caulis Spatholobi: bitter in the mouth, micro-sweet, warm in nature, return Liver Channel.Have that promoting the circulation of blood is enriched blood, the merit of relaxing muscles and tendons and activating QI and blood in the collateral.Modern study shows, Caulis Spatholobi is improved hemopoietic system, blood vessel dilating, increase Tissue Blood flow, regulates immunity, antithrombotic, antineoplastic action.
Radix Platycodonis: bitter, pungent, flat.Return lung meridian.Function with cure mainly: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Rhizoma Curcumae: pungent, bitter, temperature.Return liver, spleen channel, there is the effect of eliminating stagnation, removing blood stasis, promoting the circulation of QI to relieve pain, also have protect the liver, antiinflammatory, antitumor action.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Effect: blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping.
Radix Glycyrrhizae: coordinating the actions of various ingredients in a prescription.
The present invention is with above-mentioned medicament composing prescription, and each crude drug combined effect reaches antitumor, supports the solid gold of lung, fills blood, the effect of activating blood circulation to dissipate blood stasis, dissipating phlegm and resolving masses and conditioning the five internal organs, thereby can effectively treat pulmonary carcinoma.Below in conjunction with clinical data and model case, beneficial effect of the present invention is further illustrated.
One, clinical data:
1, physical data
Patients with Non-small-cell Lung 178 examples of choosing the outpatient service of 2009.6-2011.6 and being in hospital, age 32-68 year, 57.3 years old mean age.
2, diagnostic criteria
Western medicine diagnose standard: specified standard in the < < China common cancer diagnosis and treatment standard > > that Department of Medical Administration of Diagnosis of Non-Small Cell Lung standard employing Ministry of Health of the People's Republic of China writes.
3, Therapeutic Method
Adopt medicine of the present invention, be decocted in water for oral dose, potion, divided and sooner or later took for twice every day, within 1 month, was a course for the treatment of.
4, efficacy assessment standard: alleviate completely (CR): all visible focuses disappear completely, at least maintain more than 4 weeks; Partial rcsponse (PR): the product in tumor maximum gauge and maximum perpendicular footpath reduces more than 50%, without other focus progress, occurs without any new focus; Stable disease unchanged (SD): the product in tumor maximum gauge and maximum perpendicular footpath reduces and is less than 50%, or increase and be no more than 25%, without any new focus appearance; Progress (PD): the product in tumor maximum gauge and maximum perpendicular footpath is greater than 25%; CR+PR is total effective rate.
5, therapeutic effect: CR:83 example, PR:79 example, SD:16 example, PD:0 example.Total effective rate is 91%.
Two, model case
Case 1: Zhang, man, 62 years old.This patient's long-term smoking, start to occur cough, expectoration and dyspnea symptom in January, 2010, in July, 2010 breast CT inspection shows that right hilar shadow increases, bottom right lung patch shape shade, tracheoscopy is shown in bottom right lung dorsal segment opening neoplasm, and biopsy pathology is shown pulmonary carcinoma.Through taking medicine of the present invention, be decocted in water for oral dose, potion, divided and sooner or later took for twice every day, and cough after 3 courses for the treatment of, expectoration and dyspnea symptom obviously alleviate.Continue to take 4 months, patient's focus and symptom disappear completely, so far without recurrence.
Case 2: Zhao, man, 58 years old.Patient coughs 3 months continuously, and companion's hoarseness, feels sick, and the symptom ，Dao hospitals such as Upper abdominal pain discomfort carry out CT and MRI inspection is diagnosed as pulmonary carcinoma.Through taking medicine of the present invention, be decocted in water for oral dose, potion, divided and sooner or later took for twice every day, and after 2 courses for the treatment of, patient's cough, Upper abdominal pain, hoarseness symptom obviously alleviate.Continue to take 4 months, patient's focal symptom disappears completely, follows up a case by regular visits to 1 year without recurrence.
The specific embodiment
Embodiment 1
Formula: Radix Ginseng 10 g, Ganoderma 10 g, Radix Codonopsis 15 g, Fructus Schisandrae Chinensis 10 g, Spica Prunellae 10 g, Herba Hedyotidis Diffusae 15 g, Herba Houttuyniae 12 g, Fructus Bruceae 12 g, Semen Vaccariae 10 g, the Radix Astragali 10 g, Fructus Lycii 15 g, Fructus Ligustri Lucidi 20 g, Rhizoma Dioscoreae 18 g, Semen Euryales 15 g, the Rhizoma Atractylodis Macrocephalae 15 g, Radix Glehniae 15 g, Carapax Trionycis 20 g, Rhizoma Polygonati Odorati 18 g, Herba Dendrobii 15 g, Radix Sophorae Tonkinensis 10 g, Radix Curcumae 15 g, Radix Peucedani 12 g, Cortex Lycii 12 g, Fructus Trichosanthis 10 g, Concretio Silicea Bambusae 8 g, Radix Paeoniae Rubra 8 g, Radix Angelicae Sinensis 10g, Pseudobulbus Cremastrae Seu Pleiones 12g, Caulis Spatholobi 10g, Radix Platycodonis 10g, Rhizoma Curcumae 12g, Rhizoma Chuanxiong 15g and Radix Glycyrrhizae 5g.
Preparation and instructions of taking: decocting boils, take at twice sooner or later, within 1 month, is 1 course for the treatment of.
Claims (1)
1. a medicine for the treatment of pulmonary carcinoma, it is characterized in that, crude drug by following weight is made: Radix Ginseng 10 g, Ganoderma 10 g, Radix Codonopsis 15 g, Fructus Schisandrae Chinensis 10 g, Spica Prunellae 10 g, Herba Hedyotidis Diffusae 15 g, Herba Houttuyniae 12 g, Fructus Bruceae 12 g, Semen Vaccariae 10 g, the Radix Astragali 10 g, Fructus Lycii 15 g, Fructus Ligustri Lucidi 20 g, Rhizoma Dioscoreae 18 g, Semen Euryales 15 g, the Rhizoma Atractylodis Macrocephalae 15 g, Radix Glehniae 15 g, Carapax Trionycis 20 g, Rhizoma Polygonati Odorati 18 g, Herba Dendrobii 15 g, Radix Sophorae Tonkinensis 10 g, Radix Curcumae 15 g, Radix Peucedani 12 g, Cortex Lycii 12 g, Fructus Trichosanthis 10 g, Concretio Silicea Bambusae 8 g, Radix Paeoniae Rubra 8 g, Radix Angelicae Sinensis 10g, Pseudobulbus Cremastrae Seu Pleiones 12g, Caulis Spatholobi 10g, Radix Platycodonis 10g, Rhizoma Curcumae 12g, Rhizoma Chuanxiong 15g and Radix Glycyrrhizae 5g.
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| CN104984267A (en) * | 2015-08-03 | 2015-10-21 | 苏亮 | Traditional Chinese medicine composition for treating lung cancer |
| CN105748929A (en) * | 2016-03-31 | 2016-07-13 | 广州暨南生物医药研究开发基地有限公司 | Folium-artemisiae-argyi-containing traditional Chinese medicine composition for treating lung cancer and preparation method thereof |
| RU183040U1 (en) * | 2018-01-09 | 2018-09-07 | Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Образования "Ивановская Пожарно-Спасательная Академия Государственной Противопожарной Службы Министерства Российской Федерации По Делам Гражданской Обороны, Чрезвычайным Ситуациям И Ликвидации Последствий Стихийных Бедствий" (Ф | FIRE FIGHTING DEVICE FOR EQUIPMENT OF STORAGE ROOMS AND PARKING OF CARS |
| CN111228439A (en) * | 2019-11-07 | 2020-06-05 | 陈海林 | A Chinese medicinal composition for treating lung cancer and resisting lung cancer metastasis, and its preparation method |
| CN111700999A (en) * | 2020-07-15 | 2020-09-25 | 远见生物科技（上海）有限公司 | Pharmaceutical composition for treating lung cancer and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104984267A (en) * | 2015-08-03 | 2015-10-21 | 苏亮 | Traditional Chinese medicine composition for treating lung cancer |
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| CN111700999A (en) * | 2020-07-15 | 2020-09-25 | 远见生物科技（上海）有限公司 | Pharmaceutical composition for treating lung cancer and application thereof |
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