CN111643618A - 一种益气生津、降血糖中药组合物及其制备方法 - Google Patents
一种益气生津、降血糖中药组合物及其制备方法 Download PDFInfo
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- CN111643618A CN111643618A CN202010666091.8A CN202010666091A CN111643618A CN 111643618 A CN111643618 A CN 111643618A CN 202010666091 A CN202010666091 A CN 202010666091A CN 111643618 A CN111643618 A CN 111643618A
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Abstract
本发明公开一种益气生津、降血糖中药组合物及其制备方法。本发明的益气生津、降血糖中药组合物，包括如下重量份数的组分：人参须5‑10重量份、天冬5‑10重量份、五味子5‑10重量份、地黄5‑10重量份、玄参5‑10重量份、北沙参5‑10重量份、茯苓5‑10重量份、红花5‑10重量份、覆盆子5‑10重量份、枸杞子5‑10重量份、山药10‑15重量份、香附5‑10重量份、黄芪5‑10重量份、柏子仁5‑10重量份、天花粉10‑15重量份、土茯苓10‑15重量份。本发明的益气生津、降血糖中药组合物可达到标本兼治，对糖尿病患者能起到很好的治疗作用，且制备工艺简单，易于制作。
Description
技术领域
本发明涉及中药技术领域，尤其涉及一种益气生津、降血糖中药组合物及其制备方法。
背景技术
糖尿病(diabetes mellitus，DM)是一组由多病因引起的以慢性高血糖为特征的代谢性疾病，是由于胰岛素分泌和(或)作用缺陷所引起。其典型症状为“三多一少”，即多尿、多饮、多食和体重减轻，可伴有皮肤瘙痒。长期碳水化合物以及脂肪、蛋白质代谢紊乱还可引起多种慢性并发症的产生，如眼、肾、神经、心脏、血管等组织器官慢性进行性病变、功能减退及衰竭；病情严重或应激时可发生急性严重代谢紊乱，如糖尿病酮症酸中毒(DKA)、高渗高血糖综合征，对人体健康造成很大危害。由于饮食习惯、环境等外界因素导致糖尿病患者逐年增多，发病率高达10％以上，目前市场上治疗糖尿病以西药为主，存在终身用药、毒副作用多等问题。因此，有必要提出一种益气生津、降血糖中药组合物制备方法及应用，以解决上述问题。
发明内容
本发明提供一种益气生津、降血糖中药组合物及其制备方法，以解决现有目前市场上治疗糖尿病方式存在终身用药、毒副作用多的问题。
第一方面，本发明提供一种益气生津、降血糖中药组合物，包括如下重量份数的组分：
人参须5-10重量份、天冬5-10重量份、五味子5-10重量份、地黄5-10重量份、玄参5-10重量份、北沙参5-10重量份、茯苓5-10重量份、红花5-10重量份、覆盆子5-10重量份、枸杞子5-10重量份、山药10-15重量份、香附5-10重量份、黄芪5-10重量份、柏子仁5-10重量份、天花粉10-15重量份、土茯苓10-15重量份。
可选的，所述益气生津、降血糖中药组合物，包括如下重量份数的组分：
人参须5重量份、天冬5重量份、五味子5重量份、地黄5重量份、玄参5重量份、北沙参5重量份、茯苓5重量份、红花5重量份、覆盆子5重量份、枸杞子5重量份、山药10重量份、香附5重量份、黄芪5重量份、柏子仁5重量份、天花粉10重量份、土茯苓10重量份。
可选的，所述益气生津、降血糖中药组合物，包括如下重量份数的组分：
人参须10重量份、天冬10重量份、五味子10重量份、地黄10重量份、玄参10重量份、北沙参10重量份、茯苓10重量份、红花10重量份、覆盆子10重量份、枸杞子10重量份、山药15重量份、香附10重量份、黄芪10重量份、柏子仁10重量份、天花粉15重量份、土茯苓15重量份。
可选的，所述益气生津、降血糖中药组合物，包括如下重量份数的组分：
人参须7重量份、天冬8重量份、五味子6重量份、地黄8重量份、玄参9重量份、北沙参5重量份、茯苓6重量份、红花8重量份、覆盆子7重量份、枸杞子9重量份、山药12重量份、香附6重量份、黄芪7重量份、柏子仁5重量份、天花粉14重量份、土茯苓13重量份。
第二方面，本发明提供一种益气生津、降血糖中药组合物的制备方法，包括如下步骤：
将人参须5-10重量份粉碎成细粉，备用；
将天冬5-10重量份、五味子5-10重量份、地黄5-10重量份、玄参5-10重量份、北沙参5-10重量份、茯苓5-10重量份、红花5-10重量份、覆盆子5-10重量份、枸杞子5-10重量份、山药10-15重量份、香附5-10重量份、黄芪5-10重量份、柏子仁5-10重量份、天花粉10-15重量份、土茯苓10-15重量份，加水煎煮二次，浓缩干燥粉碎成细粉，加入人参须细粉，混匀，得到益气生津、降血糖中药组合物。
可选的，所述方法还包括：向益气生津、降血糖中药组合物添加辅料，制成口服制剂。
可选的，所述口服制剂包括：口服液、颗粒剂、片剂、硬胶囊、软胶囊以及丸剂。
可选的，所述方法还包括：将所述益气生津、降血糖中药组合物的活性组分与米、面配方加工成防治糖尿病的保健食品。
可选的，所述防治糖尿病的保健食品包括：固体饮料、压片糖果、粥、面条、面包以及饼干。
本发明的有益效果如下：本发明提供的一种益气生津、降血糖中药组合物及其制备方法，其中药组合物中所选的十六味中药材，在《本草纲目》、《神农本草经》等古籍中都有记载，是多年传承下来的传统中药材，而且大都是食材或者药食同源中药材，本品经国家批准的机构进行的急性毒性试验、长期毒性试验检查，毒副作用都尚未发现，经药效学试验和临床验证，证明益气生津、降血糖作用明显，是一款不可多得的益气生津、降血糖佳品。现在糖尿病治疗临床上多以二甲双胍、格列本脲等西药为主，肝肾损伤、恶心呕吐等等的毒副作用显著，而且患者大都要终身服药，控制血糖。该益气生津、降血糖中药组合物纯中药制剂，作用机制与二甲双胍等西药根本不同，标本兼治，对糖尿病患者能起到很好的治疗作用，且制备工艺简单，易于制作。
附图说明
为了更清楚地说明本发明实施例或现有技术中的技术方案，下面将对实施例中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图仅仅是本发明的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。
图1为本发明提供的一种益气生津、降血糖中药组合物的制备方法的流程图。
具体实施方式
为使本发明的目的、技术方案和优点更加清楚，下面将结合本发明具体实施例及相应的附图对本发明技术方案进行清楚、完整地描述。显然，所描述的实施例仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。以下结合附图，详细说明本发明各实施例提供的技术方案。
本发明提供一种益气生津、降血糖中药组合物，包括如下重量份数的组分：
人参须5-10重量份、天冬5-10重量份、五味子5-10重量份、地黄5-10重量份、玄参5-10重量份、北沙参5-10重量份、茯苓5-10重量份、红花5-10重量份、覆盆子5-10重量份、枸杞子5-10重量份、山药10-15重量份、香附5-10重量份、黄芪5-10重量份、柏子仁5-10重量份、天花粉10-15重量份、土茯苓10-15重量份。
作为一种可选的实施方式，该益气生津、降血糖中药组合物具体可以包括如下重量份数的组分：
人参须5重量份、天冬5重量份、五味子5重量份、地黄5重量份、玄参5重量份、北沙参5重量份、茯苓5重量份、红花5重量份、覆盆子5重量份、枸杞子5重量份、山药10重量份、香附5重量份、黄芪5重量份、柏子仁5重量份、天花粉10重量份、土茯苓10重量份。
作为一种可选的实施方式，该益气生津、降血糖中药组合物具体可以包括如下重量份数的组分：
人参须10重量份、天冬10重量份、五味子10重量份、地黄10重量份、玄参10重量份、北沙参10重量份、茯苓10重量份、红花10重量份、覆盆子10重量份、枸杞子10重量份、山药15重量份、香附10重量份、黄芪10重量份、柏子仁10重量份、天花粉15重量份、土茯苓15重量份。
作为一种可选的实施方式，该益气生津、降血糖中药组合物具体可以包括如下重量份数的组分：
人参须7重量份、天冬8重量份、五味子6重量份、地黄8重量份、玄参9重量份、北沙参5重量份、茯苓6重量份、红花8重量份、覆盆子7重量份、枸杞子9重量份、山药12重量份、香附6重量份、黄芪7重量份、柏子仁5重量份、天花粉14重量份、土茯苓13重量份。
该益气生津、降血糖中药组合物中所选的十六味中药材，在《本草纲目》、《神农本草经》等古籍中都有记载，或有益气生津、止渴，养阴润燥、清肺生津的功效，或能调节血糖，促进胰岛素分泌从而降低血糖的功效，这十六味中药材协同作用，使本品活性组分加强，益气生津、降血糖效果明显。经药效学试验结果表明：该降血糖中药组合物可显著降低2型糖尿病实验大鼠的血糖，糖化血红蛋白(GHb)、改善氧化应激指标，并具有显著的调节血脂功能，升高HDL-C、降低TC、TG、LDL-C，从而达到预期的效果。
上述中药组合物中所选的十六味中药材是多年传承下来的传统中药材，而且大都是食材或者药食同源中药材，本品经国家批准的机构进行的急性毒性试验、长期毒性试验检查，毒副作用都尚未发现，经药效学试验和临床验证，证明益气生津、降血糖作用明显，是一款不可多得的益气生津、降血糖佳品。现在糖尿病治疗临床上多以二甲双胍、格列本脲等西药为主，肝肾损伤、恶心呕吐等等的毒副作用显著，而且患者大都要终身服药，控制血糖。该益气生津、降血糖中药组合物纯中药制剂，作用机制与二甲双胍等西药根本不同，标本兼治，对糖尿病患者能起到很好的治疗作用。
如图1所示，本发明还提供一种益气生津、降血糖中药组合物的制备方法，包括如下步骤：
步骤一，将人参须5-10重量份粉碎成细粉，备用。
步骤二，将天冬5-10重量份、五味子5-10重量份、地黄5-10重量份、玄参5-10重量份、北沙参5-10重量份、茯苓5-10重量份、红花5-10重量份、覆盆子5-10重量份、枸杞子5-10重量份、山药10-15重量份、香附5-10重量份、黄芪5-10重量份、柏子仁5-10重量份、天花粉10-15重量份、土茯苓10-15重量份，加水煎煮二次，浓缩干燥粉碎成细粉，加入人参须细粉，混匀，得到益气生津、降血糖中药组合物。
作为一种可选的实施方式，该益气生津、降血糖中药组合物的制备方法中，具体可以选择如下重量份数的组分：
人参须5重量份、天冬5重量份、五味子5重量份、地黄5重量份、玄参5重量份、北沙参5重量份、茯苓5重量份、红花5重量份、覆盆子5重量份、枸杞子5重量份、山药10重量份、香附5重量份、黄芪5重量份、柏子仁5重量份、天花粉10重量份、土茯苓10重量份。
作为一种可选的实施方式，该益气生津、降血糖中药组合物的制备方法中，具体可以选择如下重量份数的组分：
人参须10重量份、天冬10重量份、五味子10重量份、地黄10重量份、玄参10重量份、北沙参10重量份、茯苓10重量份、红花10重量份、覆盆子10重量份、枸杞子10重量份、山药15重量份、香附10重量份、黄芪10重量份、柏子仁10重量份、天花粉15重量份、土茯苓15重量份。
作为一种可选的实施方式，该益气生津、降血糖中药组合物的制备方法中，具体可以选择如下重量份数的组分：
人参须7重量份、天冬8重量份、五味子6重量份、地黄8重量份、玄参9重量份、北沙参5重量份、茯苓6重量份、红花8重量份、覆盆子7重量份、枸杞子9重量份、山药12重量份、香附6重量份、黄芪7重量份、柏子仁5重量份、天花粉14重量份、土茯苓13重量份。
进一步地，所述方法还可以包括：向益气生津、降血糖中药组合物添加药学上允许的辅料按常规方法制成口服制剂。所述口服制剂可以包括：口服液、颗粒剂、片剂、硬胶囊、软胶囊以及丸剂等。
进一步地，所述方法还可以包括：将所述益气生津、降血糖中药组合物的活性组分与米、面配方加工成防治糖尿病的保健食品。所述防治糖尿病的保健食品可以包括：固体饮料、压片糖果、粥、面条、面包以及饼干等。
需要注意的是，这里所使用的术语仅是为了描述具体实施方式，而非意图限制根据本申请的示例性实施方式。如在这里所使用的，除非上下文另外明确指出，否则单数形式也意图包括复数形式，此外，还应当理解的是，当在本说明书中使用术语“包含”和/或“包括”时，其指明存在特征、步骤、操作、器件、组件和/或它们的组合。
以上所述仅为本发明的优选实施例而已，并不用于限制本发明，对于本领域的技术人员来说，本发明可以有各种更改和变化。凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。
Claims (9)
1.一种益气生津、降血糖中药组合物，其特征在于，包括如下重量份数的组分：
人参须5-10重量份、天冬5-10重量份、五味子5-10重量份、地黄5-10重量份、玄参5-10重量份、北沙参5-10重量份、茯苓5-10重量份、红花5-10重量份、覆盆子5-10重量份、枸杞子5-10重量份、山药10-15重量份、香附5-10重量份、黄芪5-10重量份、柏子仁5-10重量份、天花粉10-15重量份、土茯苓10-15重量份。
2.如权利要求1所述的一种益气生津、降血糖中药组合物，其特征在于，包括如下重量份数的组分：
人参须5重量份、天冬5重量份、五味子5重量份、地黄5重量份、玄参5重量份、北沙参5重量份、茯苓5重量份、红花5重量份、覆盆子5重量份、枸杞子5重量份、山药10重量份、香附5重量份、黄芪5重量份、柏子仁5重量份、天花粉10重量份、土茯苓10重量份。
3.如权利要求1所述的一种益气生津、降血糖中药组合物，其特征在于，包括如下重量份数的组分：
人参须10重量份、天冬10重量份、五味子10重量份、地黄10重量份、玄参10重量份、北沙参10重量份、茯苓10重量份、红花10重量份、覆盆子10重量份、枸杞子10重量份、山药15重量份、香附10重量份、黄芪10重量份、柏子仁10重量份、天花粉15重量份、土茯苓15重量份。
4.如权利要求1所述的一种益气生津、降血糖中药组合物，其特征在于，包括如下重量份数的组分：
人参须7重量份、天冬8重量份、五味子6重量份、地黄8重量份、玄参9重量份、北沙参5重量份、茯苓6重量份、红花8重量份、覆盆子7重量份、枸杞子9重量份、山药12重量份、香附6重量份、黄芪7重量份、柏子仁5重量份、天花粉14重量份、土茯苓13重量份。
5.一种益气生津、降血糖中药组合物的制备方法，其特征在于，包括如下步骤：
将人参须5-10重量份粉碎成细粉，备用；
将天冬5-10重量份、五味子5-10重量份、地黄5-10重量份、玄参5-10重量份、北沙参5-10重量份、茯苓5-10重量份、红花5-10重量份、覆盆子5-10重量份、枸杞子5-10重量份、山药10-15重量份、香附5-10重量份、黄芪5-10重量份、柏子仁5-10重量份、天花粉10-15重量份、土茯苓10-15重量份，加水煎煮二次，浓缩干燥粉碎成细粉，加入人参须细粉，混匀，得到益气生津、降血糖中药组合物。
6.如权利要求5所述的一种益气生津、降血糖中药组合物的制备方法，其特征在于，所述方法还包括：向益气生津、降血糖中药组合物添加辅料，制成口服制剂。
7.如权利要求6所述的一种益气生津、降血糖中药组合物的制备方法，其特征在于，所述口服制剂包括：口服液、颗粒剂、片剂、硬胶囊、软胶囊以及丸剂。
8.如权利要求5所述的一种益气生津、降血糖中药组合物的制备方法，其特征在于，所述方法还包括：将所述益气生津、降血糖中药组合物的活性组分与米、面配方加工成防治糖尿病的保健食品。
9.如权利要求8所述的一种益气生津、降血糖中药组合物的制备方法，其特征在于，所述防治糖尿病的保健食品包括：固体饮料、压片糖果、粥、面条、面包以及饼干。
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| CN1491697A (zh) * | 2003-08-21 | 2004-04-28 | 衡水市冀衡药业有限公司 | 治疗糖尿病的中药制剂及其制备方法 |
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| CN1491697A (zh) * | 2003-08-21 | 2004-04-28 | 衡水市冀衡药业有限公司 | 治疗糖尿病的中药制剂及其制备方法 |
Non-Patent Citations (1)
| Title |
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| 国家药品监督管理局编: "《国家中成药标准汇编 内科 气血津液 分册》", 31 December 2002 * |
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