CN111544561A

CN111544561A - Pharmaceutical composition for treating poultry influenza and preparation method thereof

Info

Publication number: CN111544561A
Application number: CN202010512692.3A
Authority: CN
Inventors: 郭万恒; 郭金皋; 田勇
Original assignee: Shijiazhuang Hengtaihe Animal Pharmacy Co ltd
Current assignee: Shijiazhuang Hengtaihe Animal Pharmacy Co ltd
Priority date: 2020-06-08
Filing date: 2020-06-08
Publication date: 2020-08-18

Abstract

The invention discloses a pharmaceutical composition for treating poultry influenza, which comprises the following components in parts by weight: 10-16 parts of buffalo horn, 35-55 parts of nacre, 18-26 parts of pumice, 18-26 parts of gardenia, 10-16 parts of burdock, 10-16 parts of roasted ephedra, 6-12 parts of ginger, 6-12 parts of picrorhiza rhizome, 6-12 parts of rhizoma acori graminei and 4-8 parts of liquorice. The formula disclosed by the invention has the advantages of small toxic and side effects, no drug resistance, difficulty in residue and the like, and can be used for remarkably improving the organism immunity and anti-stress capability of poultry and resisting the occurrence and spread of avian influenza.

Description

Pharmaceutical composition for treating poultry influenza and preparation method thereof

Technical Field

The invention relates to the technical field related to livestock breeding, in particular to a pharmaceutical composition for treating poultry influenza and a preparation method and application thereof.

Background

Avian influenza can be classified into three major groups, high pathogenicity, low pathogenicity and non-pathogenicity, depending on the type of pathogen. Non-pathogenic avian influenza does not cause obvious symptoms, and only makes the bodies of infected birds produce virus antibodies. The low pathogenicity avian influenza can cause the poultry to have mild respiratory symptoms, reduce the food intake, reduce the egg production and cause sporadic death. Highly pathogenic avian influenza is the most severe, the morbidity and mortality are high, and infected chicken flocks are often covered by the whole army. Avian influenza has become one of the major diseases affecting the current productivity benefits of poultry, and control of this disease and secondary infections has become a major target for disease control in poultry.

In recent years, on one hand, the poultry breeding industry develops rapidly, presents a good situation of large-scale production, and becomes one of important ways for getting rich by a family; in the process of modernized intensive poultry breeding, disease prevention and treatment are important factors directly influencing the economic benefit of poultry breeding. The current poultry farms generally adopt measures such as increasing the feeding density and the like, so that poultry are easy to be infected with avian influenza. On the other hand, poultry have weak resistance to avian influenza diseases and high mortality rate, which causes considerable economic loss to production operators. At present, no good therapeutic medicine exists for the disease. Therefore, how to treat the poultry influenza and promote the healthy growth of the poultry is particularly important and is an important problem to be solved urgently in the poultry breeding process.

Disclosure of Invention

The invention aims to solve the technical problem of providing a pharmaceutical composition for treating poultry influenza and a preparation method thereof.

In order to solve the technical problems, the technical scheme adopted by the invention is as follows.

The pharmaceutical composition for treating poultry influenza comprises the following components in parts by weight: 8-20 parts of buffalo horn, 30-60 parts of nacre, 15-30 parts of pumice, 15-30 parts of gardenia, 8-20 parts of burdock, 8-20 parts of roasted ephedra, 5-15 parts of ginger, 5-15 parts of picrorhiza rhizome, 5-15 parts of rhizoma acori graminei and 2-10 parts of liquorice.

As a preferable technical scheme of the invention, the pharmaceutical composition comprises the following components in parts by weight: 10-16 parts of buffalo horn, 35-55 parts of nacre, 18-26 parts of pumice, 18-26 parts of gardenia, 10-16 parts of burdock, 10-16 parts of roasted ephedra, 6-12 parts of ginger, 6-12 parts of picrorhiza rhizome, 6-12 parts of rhizoma acori graminei and 4-8 parts of liquorice.

As a preferable technical scheme of the invention, the pharmaceutical composition comprises the following components in parts by weight: 13 parts of buffalo horn, 45 parts of nacre, 22 parts of pumice, 22 parts of gardenia, 13 parts of burdock, 13 parts of roasted ephedra, 9 parts of ginger, 9 parts of picrorhiza rhizome, 9 parts of rhizoma acori graminei and 6 parts of liquorice.

As a preferable technical scheme of the invention, the pharmaceutical composition comprises the following components in parts by weight: 12 parts of buffalo horn, 50 parts of nacre, 25 parts of pumice, 20 parts of gardenia, 10 parts of burdock, 12 parts of roasted ephedra, 9 parts of ginger, 6 parts of rhizoma picrorhizae, 10 parts of rhizoma acori graminei and 7 parts of liquorice.

As a preferable technical scheme of the invention, the pharmaceutical composition comprises the following components in parts by weight: 15 parts of buffalo horn, 40 parts of nacre, 20 parts of pumice, 22 parts of gardenia, 15 parts of burdock, 14 parts of roasted ephedra, 7 parts of ginger, 8 parts of picrorhiza rhizome, 12 parts of rhizoma acori graminei and 5 parts of liquorice.

As a preferable technical scheme of the invention, the pharmaceutical composition comprises the following components in parts by weight: 16 parts of buffalo horn, 55 parts of nacre, 26 parts of pumice, 26 parts of gardenia, 16 parts of burdock, 16 parts of roasted ephedra, 2 parts of ginger, 12 parts of picrorhiza rhizome, 12 parts of rhizoma acori graminei and 8 parts of liquorice.

As a preferable technical scheme of the invention, the pharmaceutical composition comprises the following components in parts by weight: 10 parts of buffalo horn, 35 parts of nacre, 18 parts of pumice, 18 parts of gardenia, 10 parts of burdock, 10 parts of roasted ephedra, 6 parts of ginger, 6 parts of rhizoma picrorhizae, 6 parts of rhizoma acori graminei and 4 parts of liquorice.

A method for preparing a pharmaceutical composition for treating avian influenza, the method comprising the steps of: A. weighing the material components according to the weight part ratio for later use; B. preparing an extracting solution: taking oxhorn, nacre, pumice and burdock to respectively crush into fine powder, wrapping the fine powder with a sandbag, adding 5-30 times of water by weight, decocting for 2-4 hours, and filtering to obtain an extracting solution I; C. preparing an extracting solution: decocting the residual materials and the dregs obtained in the previous step for 2-3 times, adding 5-20 times of water for decocting for 1-2 hours each time, mixing decoctions, and filtering to obtain an extracting solution II; D. and combining the first extract and the second extract, and concentrating under reduced pressure until the relative density is 1.1-1.3 to obtain a concentrated solution.

As a preferred technical scheme of the invention, the preparation method further comprises the following post-treatment process: adding water into the concentrated solution to prepare oral liquid and/or injection.

As a preferred technical scheme of the invention, the preparation method further comprises the following post-treatment process: adding adjuvants into the concentrated solution, and making into tablet, pill, dripping pill, or granule.

Adopt the produced beneficial effect of above-mentioned technical scheme to lie in: avian influenza is an exogenous disease caused by the repeated affection of pathogenic wind, cold, dryness, summer-heat, dampness, fire (warm, hot) or epidemic toxin under the condition of insufficient vital qi of the body of the domestic fowls. The healthy qi is not coherent with the pathogenic factors, and the pathogenic factors play a role and the qi must be deficient. If the healthy qi of the poultry body is sufficient, that is, the organs are dynamically balanced, the flu does not sufficiently develop even when the poultry suffers from the external infection. Therefore, the first key point of preventing and treating influenza is to ensure the health of poultry bodies and sufficient healthy qi and enhance the capability of the bodies to resist viruses, stress and various external environments. The formula disclosed by the invention has the advantages of small toxic and side effects, no drug resistance, difficulty in residue and the like, and can be used for remarkably improving the organism immunity and anti-stress capability of poultry and resisting the occurrence and spread of avian influenza.

Detailed Description

The following examples illustrate the invention in detail. The raw materials and various devices used in the invention are conventional commercially available products, and can be directly obtained by market purchase.

In the following description of embodiments, for purposes of explanation and not limitation, specific details are set forth, such as particular system structures, techniques, etc. in order to provide a thorough understanding of the embodiments of the present application. It will be apparent, however, to one skilled in the art that the present application may be practiced in other embodiments that depart from these specific details. In other instances, detailed descriptions of well-known systems, devices, circuits, and methods are omitted so as not to obscure the description of the present application with unnecessary detail.

It will be understood that the terms "comprises" and/or "comprising," when used in this specification and the appended claims, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof.

It should also be understood that the term "and/or" as used in this specification and the appended claims refers to and includes any and all possible combinations of one or more of the associated listed items.

As used in this specification and the appended claims, the term "if" may be interpreted contextually as "when", "upon" or "in response to" determining "or" in response to detecting ". Similarly, the phrase "if it is determined" or "if a [ described condition or event ] is detected" may be interpreted contextually to mean "upon determining" or "in response to determining" or "upon detecting [ described condition or event ]" or "in response to detecting [ described condition or event ]".

Furthermore, in the description of the present application and the appended claims, the terms "first," "second," "third," and the like are used for distinguishing between descriptions and not necessarily for describing or implying relative importance.

Reference throughout this specification to "one embodiment" or "some embodiments," or the like, means that a particular feature, structure, or characteristic described in connection with the embodiment is included in one or more embodiments of the present application. Thus, appearances of the phrases "in one embodiment," "in some embodiments," "in other embodiments," or the like, in various places throughout this specification are not necessarily all referring to the same embodiment, but rather "one or more but not all embodiments" unless specifically stated otherwise. The terms "comprising," "including," "having," and variations thereof mean "including, but not limited to," unless expressly specified otherwise.

The pharmacological effects are as follows:

buffalo horn, name of traditional Chinese medicine. Is a substitute of traditional Chinese medicine rhinoceros horn and has the functions of clearing heat, cooling blood, arresting convulsion and detoxifying. Treating cold, epidemic febrile disease, fever in blood system, mania, dysphoria, delirium, macula, jaundice, hematemesis, epistaxis, hemorrhage, superficial infection, toxic swelling

Concha Margaritifera has effects of suppressing hyperactive liver, subsiding yang, removing liver fire, improving eyesight, calming heart and tranquilizing mind. Has tranquilizing, anticonvulsive, gastric acid secretion reducing, ulcer healing promoting, and anoxia resisting effects.

The pumice mainly clears away the lung-heat and reduces phlegm, and has good treatment effect on symptoms such as chronic cough, phlegm-heat cough and hemoptysis

Cape jasmine has the effects of purging fire, relieving restlessness, clearing heat, promoting diuresis, cooling blood and removing toxicity; it can be used topically for relieving swelling and pain. Can be used for treating febrile vexation, damp-heat jaundice, stranguria with pain, hematemesis, epistaxis, conjunctival congestion, swelling and pain, and pyocutaneous disease due to fire toxin, and for treating sprain, contusion and pain.

The main treatment effects of the great burdock achene and great burdock achene are wind and heat dispelling, heat clearing, detoxifying, eruption promoting, lung ventilating, sore throat relieving and swelling eliminating. It can be used for treating wind-heat type common cold and sore throat. The product has effects of dispelling pathogenic wind and heat, dispersing lung qi and relieving sore throat, and can be used for treating wind-heat type common cold and sore throat,

the efficacy of mix-fried ephedra herb is to induce sweating and dispel cold, ventilate lung and relieve asthma, induce diuresis and alleviate edema. In clinic, the traditional Chinese medicine composition is often applied to wind-cold type cold, edema, chest distress, dyspnea and suffocation and cough. The use frequency of the mix-fried ephedra herb in clinic is higher, the effect of the mix-fried ephedra herb is particularly good for the exterior syndrome of wind-cold type, the common symptoms are acute upper respiratory tract infection and acute tonsillitis, and the effect of the mix-fried ephedra herb is the best particularly for the symptom of fever without sweat.

The ginger and ginger special gingerol can stimulate gastrointestinal mucosa to enhance the congestion and digestive ability of the gastrointestinal tract. It can effectively treat abdominal pain, diarrhea, abdominal distention, emesis and the like caused by excessive cold and cool food. After eating the ginger, people can feel hot because the ginger can expand blood vessels, accelerate blood circulation and promote pores on the bodies to open, so that not only can redundant heat be taken away, but also pathogenic bacteria and cold in the bodies can be taken away together.

Rhizoma picrorhizae and rhizoma picrorhizae are rhizome of Scrophulariaceae plant rhizoma picrorhizae and Tibetan rhizoma picrorhizae. It is bitter in taste and cold in nature, and enters liver meridian, stomach meridian and large intestine meridian. Has the functions of clearing and reducing deficiency heat, cooling blood and stopping bleeding, clearing heat and drying dampness, killing insects and eliminating malnutrition. It can be used for treating night sweat due to yin deficiency, hectic fever, infantile malnutrition, jaundice, dysentery, hematemesis, epistaxis, conjunctival congestion, swelling and pain, carbuncle, swelling, and pyocutaneous disease.

The grassleaf sweelflag rhizome has a plurality of efficacies and effects, mainly has the effects of resolving dampness and stimulating appetite, inducing resuscitation and eliminating phlegm, refreshing mind and benefiting intelligence, coma and epilepsy, amnesia and deafness and the like, and can regulate qi, activate blood, dispel wind and dampness, treat epilepsy, phlegm syncope, fever and coma, amnesia, qi block and deafness, chest and dysphoria, stomachache, bellyache, anemofrigid-damp arthralgia, traumatic injury and the like

The liquorice and liquorice have the effects of tonifying spleen and qi, clearing away heat and toxic materials, eliminating phlegm and stopping cough, relieving spasm and pain and harmonizing the medicines. The traditional Chinese medicine composition is clinically used for treating weakness of spleen and stomach, lassitude and hypodynamia, palpitation and shortness of breath, cough and excessive phlegm, abdominal and limb spasm and pain, carbuncle and sore toxin, and relieving the toxicity of the medicine. In daily life, when the body has symptoms of palpitation, severe palpitation, intermittent pulse, deficiency of spleen-stomach qi, lassitude and weakness caused by deficiency of both qi and blood, the body can be comprehensively conditioned by matching liquorice with other medicines. When the body has swollen sore throat, carbuncle, cellulitis and sore and ulcer, the Chinese medicinal composition has good treatment effect when being taken orally or applied externally. When asthma and cough appear in the body, the traditional Chinese medicine composition can be matched with other cough-relieving and phlegm-reducing medicines, and has good treatment effects on wind-heat cough and wind-cold cough of the body.

Example 1

The pharmaceutical composition for treating poultry influenza comprises the following components in parts by weight: 13 parts of buffalo horn, 45 parts of nacre, 22 parts of pumice, 22 parts of gardenia, 13 parts of burdock, 13 parts of roasted ephedra, 9 parts of ginger, 9 parts of picrorhiza rhizome, 9 parts of rhizoma acori graminei and 6 parts of liquorice.

Example 2

A preparation method of a pharmaceutical composition for treating poultry influenza comprises the following steps: A. weighing the material components according to the weight part ratio for later use; B. preparing an extracting solution: pulverizing cornu bovis Seu Bubali, Concha Margaritifera, Pumex, and fructus Arctii into fine powder, wrapping with sandbag, decocting with 18 weight times of water for 2-4 hr, and filtering to obtain extractive solution I; C. preparing an extracting solution: decocting the residual materials and the dregs obtained in the previous step for 2-3 times, adding 12 weight times of water for each time, decocting for 1-2 hours, mixing decoctions, and filtering to obtain an extracting solution II; D. and combining the first extract and the second extract, and concentrating under reduced pressure until the relative density is 1.1-1.3 to obtain a concentrated solution.

Example 3

Dosage form selection of the pharmaceutical composition for treating poultry influenza: the concentrated solution obtained in the above embodiment is added with water to prepare oral liquid and/or injection.

Example 4

Dosage form selection of the pharmaceutical composition for treating poultry influenza: the concentrated solution obtained in the above embodiment is added with auxiliary materials to prepare tablets, pills, dripping pills and granules.

Example 5

Safety test

The medicinal composition in the embodiment 1 of the invention is mixed with common feed for laying hens and stirred uniformly, the mixed feed is used for feeding mice, the mice are continuously fed and observed for 30 days, the skin and hair of the mice are smooth, the mice are normal in eating and drinking water, normal in behavior and activity, normal in weight increase, the biochemical index and hematology of blood fluctuate within a normal range, the urinary index and the marrow index fluctuate within a normal range, the tissue organs are not abnormal, and the whole body has no toxicological reaction. No death and abnormal toxic reaction are seen in the test period, the test mouse is dissected after the test is finished, and the liver, the kidney, the spleen, the stomach, the heart, the lung and the intestine are observed and have no abnormal change.

Then 1000 laying hens which lay eggs normally are fed, the laying hens are divided into a control group and a test group, the control group is fed with common laying hen feed without any additive, the test group is fed with the feed added with the pharmaceutical composition in the embodiment 1, the feeding and egg laying conditions of the two groups of laying hens are normal and do not occur abnormally after the feeding is continued for 30 days, wherein the weight of the laying hens in the test group is obviously increased, and wings are bright.

The prevalence rate of the avian influenza is related to the immunity of the organism, the immunity of the organism is strong, the resistance to the influenza is strong, the avian influenza is not easy to suffer from, or the cure rate after suffering from the avian influenza is quicker than the recovery of the immunity which is lower. The lymphocyte transformation rate is an important index for evaluating the cellular immune function of an organism, and the level of the antibody after vaccine immunization reflects the humoral immune capability of the organism, so after the feed of the pharmaceutical composition disclosed by the invention is fed, the lymphocyte transformation rate of the laying hen and the level of the avian influenza antibody are measured, and the influence of the pharmaceutical composition disclosed by the invention on the immune function of the organism is verified.

Organism detection is carried out on the two groups of laying hens, and the lymphocyte conversion rate and the avian influenza antibody level detection results of the two groups of laying hens are shown in the table 1:

table 1 results of detecting lymphocyte transformation rate and avian influenza antibody level of laying hens:

experiments show that the method has good effect on treating early avian influenza, can effectively improve the lymphocyte transformation rate and avian influenza antibody level of chickens, and enhances the autoimmune capability of organisms.

Control experiments were performed in the ligusticum city breeding area. The breeding test is carried out on 1000 laying hens suffering from avian influenza, and the breeding test is divided into two groups, one group is normally fed with common chicken feed, and the other group is administered with the pharmaceutical composition in the embodiment 1 of the invention except for the normal feeding of the common chicken feed, and the administration method comprises the following steps: orally administering the medicine according to the amount of 0.3-0.5 g crude drug per Kg of the weight of each poultry; the amount of the crude drug is 0.1-0.2 g/Kg per poultry. The mortality, laying rate and growth status of the two groups of laying hens were shown in table 2, 2 times a day, for 30 days in succession:

table 2 detection results of laying rate, growth status and mortality of layer chickens:

experiments show that the method has good effect on treating early avian influenza, can improve symptoms, improve the growth condition of sick chickens, increase the laying rate, increase the feed intake and increase the survival rate.

Example 6

This embodiment is different from embodiment 1 in that: the pharmaceutical composition comprises the following components in parts by weight: 12 parts of buffalo horn, 50 parts of nacre, 25 parts of pumice, 20 parts of gardenia, 10 parts of burdock, 12 parts of roasted ephedra, 9 parts of ginger, 6 parts of rhizoma picrorhizae, 10 parts of rhizoma acori graminei and 7 parts of liquorice.

Example 7

This embodiment is different from embodiment 1 in that: the pharmaceutical composition comprises the following components in parts by weight: 15 parts of buffalo horn, 40 parts of nacre, 20 parts of pumice, 22 parts of gardenia, 15 parts of burdock, 14 parts of roasted ephedra, 7 parts of ginger, 8 parts of picrorhiza rhizome, 12 parts of rhizoma acori graminei and 5 parts of liquorice.

Example 8

This embodiment is different from embodiment 1 in that: the pharmaceutical composition comprises the following components in parts by weight: 16 parts of buffalo horn, 55 parts of nacre, 26 parts of pumice, 26 parts of gardenia, 16 parts of burdock, 16 parts of roasted ephedra, 2 parts of ginger, 12 parts of picrorhiza rhizome, 12 parts of rhizoma acori graminei and 8 parts of liquorice.

Example 9

This embodiment is different from embodiment 1 in that: the pharmaceutical composition comprises the following components in parts by weight: 10 parts of buffalo horn, 35 parts of nacre, 18 parts of pumice, 18 parts of gardenia, 10 parts of burdock, 10 parts of roasted ephedra, 6 parts of ginger, 6 parts of rhizoma picrorhizae, 6 parts of rhizoma acori graminei and 4 parts of liquorice.

In conclusion, the breeding test shows that the formula disclosed by the invention has the advantages of small toxic and side effects, no drug resistance, difficulty in residue and the like, and can be used for remarkably improving the organism immunity and anti-stress capability of poultry and resisting the occurrence and spread of avian influenza.

The above-mentioned embodiments are only used for illustrating the technical solutions of the present invention, and not for limiting the same; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not substantially depart from the spirit and scope of the embodiments of the present invention, and are intended to be included within the scope of the present invention.

Claims

1. A pharmaceutical composition for treating poultry influenza, which is characterized in that: the pharmaceutical composition comprises the following components in parts by weight: 8-20 parts of buffalo horn, 30-60 parts of nacre, 15-30 parts of pumice, 15-30 parts of gardenia, 8-20 parts of burdock, 8-20 parts of roasted ephedra, 5-15 parts of ginger, 5-15 parts of picrorhiza rhizome, 5-15 parts of rhizoma acori graminei and 2-10 parts of liquorice.

2. The pharmaceutical composition for treating avian influenza according to claim 1, wherein: the method is characterized in that: the pharmaceutical composition comprises the following components in parts by weight: 10-16 parts of buffalo horn, 35-55 parts of nacre, 18-26 parts of pumice, 18-26 parts of gardenia, 10-16 parts of burdock, 10-16 parts of roasted ephedra, 6-12 parts of ginger, 6-12 parts of picrorhiza rhizome, 6-12 parts of rhizoma acori graminei and 4-8 parts of liquorice.

3. The pharmaceutical composition for treating avian influenza according to claim 1, wherein: the method is characterized in that: the pharmaceutical composition comprises the following components in parts by weight: 13 parts of buffalo horn, 45 parts of nacre, 22 parts of pumice, 22 parts of gardenia, 13 parts of burdock, 13 parts of roasted ephedra, 9 parts of ginger, 9 parts of picrorhiza rhizome, 9 parts of rhizoma acori graminei and 6 parts of liquorice.

4. The pharmaceutical composition for treating avian influenza according to claim 1, wherein: the method is characterized in that: the pharmaceutical composition comprises the following components in parts by weight: 12 parts of buffalo horn, 50 parts of nacre, 25 parts of pumice, 20 parts of gardenia, 10 parts of burdock, 12 parts of roasted ephedra, 9 parts of ginger, 6 parts of rhizoma picrorhizae, 10 parts of rhizoma acori graminei and 7 parts of liquorice.

5. The pharmaceutical composition for treating avian influenza according to claim 1, wherein: the method is characterized in that: the pharmaceutical composition comprises the following components in parts by weight: 15 parts of buffalo horn, 40 parts of nacre, 20 parts of pumice, 22 parts of gardenia, 15 parts of burdock, 14 parts of roasted ephedra, 7 parts of ginger, 8 parts of picrorhiza rhizome, 12 parts of rhizoma acori graminei and 5 parts of liquorice.

6. The pharmaceutical composition for treating avian influenza according to claim 1, wherein: the method is characterized in that: the pharmaceutical composition comprises the following components in parts by weight: 16 parts of buffalo horn, 55 parts of nacre, 26 parts of pumice, 26 parts of gardenia, 16 parts of burdock, 16 parts of roasted ephedra, 2 parts of ginger, 12 parts of picrorhiza rhizome, 12 parts of rhizoma acori graminei and 8 parts of liquorice.

7. The pharmaceutical composition for treating avian influenza according to claim 1, wherein: the method is characterized in that: the pharmaceutical composition comprises the following components in parts by weight: 10 parts of buffalo horn, 35 parts of nacre, 18 parts of pumice, 18 parts of gardenia, 10 parts of burdock, 10 parts of roasted ephedra, 6 parts of ginger, 6 parts of rhizoma picrorhizae, 6 parts of rhizoma acori graminei and 4 parts of liquorice.

8. A preparation method of a pharmaceutical composition for treating poultry influenza is characterized by comprising the following steps: the method comprises the following steps:

A. weighing the material components according to the weight part ratio for later use;

B. preparing an extracting solution: taking oxhorn, nacre, pumice and burdock to respectively crush into fine powder, wrapping the fine powder with a sandbag, adding 5-30 times of water by weight, decocting for 2-4 hours, and filtering to obtain an extracting solution I;

C. preparing an extracting solution: decocting the residual materials and the dregs obtained in the previous step for 2-3 times, adding 5-20 times of water for decocting for 1-2 hours each time, mixing decoctions, and filtering to obtain an extracting solution II;

D. and combining the first extract and the second extract, and concentrating under reduced pressure until the relative density is 1.1-1.3 to obtain a concentrated solution.

9. The method for preparing a pharmaceutical composition for treating avian influenza according to claim 8, wherein the pharmaceutical composition comprises: the preparation method also comprises the following post-treatment process: adding water into the concentrated solution to prepare oral liquid and/or injection.

10. The method for preparing a pharmaceutical composition for treating avian influenza according to claim 8, wherein the pharmaceutical composition comprises: the preparation method also comprises the following post-treatment process: adding adjuvants into the concentrated solution, and making into tablet, pill, dripping pill, or granule.