CN107648398A - Treat the Chinese medicine composition of escherichia coli of piglets type stomach and intestine oedema - Google Patents
Treat the Chinese medicine composition of escherichia coli of piglets type stomach and intestine oedema Download PDFInfo
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- CN107648398A CN107648398A CN201711066772.5A CN201711066772A CN107648398A CN 107648398 A CN107648398 A CN 107648398A CN 201711066772 A CN201711066772 A CN 201711066772A CN 107648398 A CN107648398 A CN 107648398A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
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Abstract
The present invention relates to a kind of Chinese medicine composition for treating escherichia coli of piglets type stomach and intestine oedema and preparation method thereof, the component and its ratio of weight and number of the Chinese medicine composition are respectively：10 40 parts of the bighead atractylodes rhizome；10 40 parts of akebi；10 35 parts of the coptis；10 35 parts of Poria cocos；10 35 parts of rhizoma alismatis；5 25 parts of waxgourd peel；5 25 parts of Divine Comedy；5 25 parts of umbellate pore furgus；5 20 parts of Asiatic plantain；5 20 parts of radix glycyrrhizae.The present invention has the effect of clearing heat and detoxicating, air making-up and spleen enlivening antidiarrheal, and preparation method is simple, easy to use, toxic side effect is small, drug residue free, is a kind of effective Chinese medicine composition for treating piglet stomach and intestine diarrhea caused by Escherichia coli.
Description
Technical field
The invention belongs to field of veterinary, especially a kind of Chinese medicine composition for treating escherichia coli of piglets type stomach and intestine oedema
And preparation method thereof.
Background technology
Escherichia coli of piglets type stomach and intestine oedema is to be colonized in infectiousness intestines caused by enteral enteropathogenic E. Coli
Endotoxemia.Clinically using acute death, eyelid swelled, call hoarse, nervous symptoms and greater curvature and mesocolon oedema as
Feature.It can occur throughout the year, clinic is mainly shown as incoordination, and four limbs tamper, shape of seemingly swimming, the common face of sick pig,
Palpebral edema, severe one are extended down to face, neck, and head becomes fat.Because the cause of disease is complicated, this sick remedy measures is seldom.The present invention takes aim at
The drawbacks of quasi- escherichia coli of piglets type stomach and intestine oedema, start with from Chinese herbal medicine and studied.
The content of the invention
The present invention has the effect of clearing heat and detoxicating, air making-up and spleen enlivening antidiarrheal, and preparation method is simple, easy to use, price is low
It is honest and clean, toxic side effect is small, drug residue free, be a kind of Chinese traditional medicine composition of good treatment escherichia coli of piglets type stomach and intestine oedema
Thing.
It is another object of the present invention to provide a kind of Chinese traditional medicine composition for treating escherichia coli of piglets type stomach and intestine oedema
The preparation method of thing.
The present invention is achieved by the following technical solutions：
A kind of Chinese medicine composition for treating escherichia coli of piglets type stomach and intestine oedema, the component of its Chinese medicine composition and its again
Measuring portion rate is respectively：
Bighead atractylodes rhizome 10-40 parts；
Akebi 10-40 parts；
Coptis 10-35 parts；
Poria cocos 10-35 parts；
Rhizoma alismatis 10-35 parts；
Waxgourd peel 5-25 parts；
Divine Comedy 5-25 parts；
Umbellate pore furgus 5-25 parts；
Asiatic plantain 5-20 parts；
Radix glycyrrhizae 5-20 parts.
A kind of preparation method for the Chinese medicine composition for treating escherichia coli of piglets type stomach and intestine oedema, the step of its preparation method
It is rapid as follows：
(1) bighead atractylodes rhizome, akebi, the coptis, Poria cocos, rhizoma alismatis, waxgourd peel, Divine Comedy, umbellate pore furgus, Chinese herbaceous peony are weighed respectively according to weight proportion
Grass and radix glycyrrhizae are crushed, and all pass through 100 mesh sieves respectively；
(2) by the bighead atractylodes rhizome after being sieved in step (1), akebi, the coptis, Poria cocos, rhizoma alismatis, waxgourd peel, Divine Comedy, umbellate pore furgus, Chinese herbaceous peony
Grass and radix glycyrrhizae are put into blending tank, are sufficiently mixed uniformly, that is, the Chinese medicine group for the escherichia coli of piglets type stomach and intestine oedema that obtains medical treatment
Compound finished product.
Advantages of the present invention and beneficial effect are：
1st, the bighead atractylodes rhizome, akebi, the coptis, the Fu contained in the Chinese medicine composition of this treatment escherichia coli of piglets type stomach and intestine oedema
The Chinese medicinal ingredients such as Siberian cocklebur, rhizoma alismatis, waxgourd peel, Divine Comedy, umbellate pore furgus, Asiatic plantain and radix glycyrrhizae, antiviral, antiphlogistic antibacterial, air making-up and spleen enlivening antidiarrheal
And other effects it is good.
2nd, Chinese medicine composition of the invention absorbs well, and be not easy to quite stable in the environment in gastric tissue after taking orally
Influenceed by temperature, acid-base value, the blood concentration required for treatment can be reached in the short period of time.
Embodiment
The present invention is described in further detail by following examples.It should be noted that：Following embodiments are illustrative, are not
It is limited, it is impossible to limit protection scope of the present invention with following embodiments.
The bighead atractylodes rhizome, akebi, the coptis, Poria cocos, rhizoma alismatis, waxgourd peel, Divine Comedy, umbellate pore furgus, Asiatic plantain and radix glycyrrhizae involved in the present invention
Can commercially it be commercially available.
Embodiment 1
A kind of Chinese medicine composition for treating escherichia coli of piglets type stomach and intestine oedema, the component of its Chinese medicine composition and its again
Amount is respectively：
Bighead atractylodes rhizome 40g, akebi 40g, coptis 35g, Poria cocos 35g, rhizoma alismatis 35g, waxgourd peel 25g, Divine Comedy 25g, umbellate pore furgus 25g, car
Preceding careless 20g, radix glycyrrhizae 20g.
A kind of preparation method for the Chinese medicine composition for treating escherichia coli of piglets type stomach and intestine oedema, the step of preparation technology
It is as follows：
(1) bighead atractylodes rhizome, akebi, the coptis, Poria cocos, rhizoma alismatis, waxgourd peel, Divine Comedy, umbellate pore furgus, Chinese herbaceous peony are weighed respectively according to weight proportion
Grass and radix glycyrrhizae are crushed, and all pass through 100 mesh sieves respectively；
(2) by the bighead atractylodes rhizome after being sieved in step (1), akebi, the coptis, Poria cocos, rhizoma alismatis, waxgourd peel, Divine Comedy, umbellate pore furgus, Chinese herbaceous peony
Grass and radix glycyrrhizae are put into blending tank, are sufficiently mixed uniformly, that is, the Chinese medicine group for the escherichia coli of piglets type stomach and intestine oedema that obtains medical treatment
Compound finished product.
Embodiment 2
A kind of Chinese medicine composition for treating escherichia coli of piglets type stomach and intestine oedema, the component of its Chinese medicine composition and its again
Amount is respectively：
Bighead atractylodes rhizome 10kg, akebi 10kg, coptis 10kg, Poria cocos 10kg, rhizoma alismatis 10kg, waxgourd peel 5kg, Divine Comedy 5kg, umbellate pore furgus
5kg, Asiatic plantain 5kg, radix glycyrrhizae 5kg.
The step of its preparation method, is the same as embodiment 1.
Embodiment 3
A kind of Chinese medicine composition for treating escherichia coli of piglets type stomach and intestine oedema, the component of its Chinese medicine composition and its again
Amount is respectively：
Bighead atractylodes rhizome 30kg, akebi 30kg, coptis 30kg, Poria cocos 30kg, rhizoma alismatis 20kg, waxgourd peel 15kg, Divine Comedy 15kg, umbellate pore furgus
15kg, Asiatic plantain 10kg, radix glycyrrhizae 10kg.
The step of its preparation method, is the same as embodiment 1.
Clinical practice
In order to verify clinical therapeutic efficacy of the present invention to escherichia coli of piglets type stomach and intestine oedema, we are right with the present invention
The case of pig natural infection escherichia coli of piglets type stomach and intestine oedema has carried out efficacy experiment.Experiment by the present invention be divided into it is low, in,
High three dosage carries out packet administration to animal, compared with the infection control group of escherichia coli of piglets type stomach and intestine oedema,
So as to evaluate the therapeutic effect of the present invention and optimum amount.
1 material and method
In the piglet 30 for suffering from escherichia coli of piglets type stomach and intestine oedema in the pig farm of Tianjin Wuqing District to being diagnosed as
Carry out effect test of the present invention.
2 experimental animals are grouped and processing
The sick pig of abiogenous escherichia coli of piglets type stomach and intestine oedema is randomly divided into 5 groups, every group 6.
1 group is tested as infection control group, is not processed.
It is low dose group of the present invention to test 2 groups, and 1/2 times of amount (per kilogram of body weight 1g) of clinical recommended dose is administered, spice,
Successive administration 5 days.
It is middle dose group of the present invention to test 3 groups, clinical recommended dose (per kilogram of body weight 2g) administration, spice, successive administration 5
My god.
It is high dose group of the present invention to test 4 groups, 2 times of amount (per kilogram of body weight 4g) administrations of clinical recommended dose, spice, is connected
Continuous administration 5 days.
It is Injection of Norfloxacin group to test 5 groups, is used to specifications：Twice daily, intramuscular injection, per kilogram of body weight
5mL amount administration, successive administration 5 days.
3 result of the tests
To natural infection escherichia coli of piglets type stomach and intestine oedema, after the administration of this Chinese medicine composition spice, by with infection
Control group is compared, and the clinical symptoms of morbid pig substantially mitigate.The therapeutic effect of middle dose group has reached preferable requirement.Knot
Fruit is shown in Table 1.
The observation of curative effect of table 1
4 interpretations of result
Analyzed in terms of clinical symptoms, inefficiency, cure rate three, the therapeutic effect of middle dose group apparently higher than its
His treatment group.The present invention is administered by per kilogram of body weight 4g, and spice, continuous 5 days to clinical type escherichia coli of piglets type stomach and intestine oedema
Disease has good therapeutic effect.
Claims (2)
- A kind of 1. Chinese medicine composition for treating escherichia coli of piglets type stomach and intestine oedema, it is characterised in that：The Chinese medicine composition Component and its ratio of weight and number are respectively：Bighead atractylodes rhizome 10-40 parts；Akebi 10-40 parts；Coptis 10-35 parts；Poria cocos 10-35 parts；Rhizoma alismatis 10-35 parts；Waxgourd peel 5-25 parts；Divine Comedy 5-25 parts；Umbellate pore furgus 5-25 parts；Asiatic plantain 5-20 parts；Radix glycyrrhizae 5-20 parts.
- A kind of 2. preparation side of the Chinese medicine composition for the treatment of escherichia coli of piglets type stomach and intestine oedema as claimed in claim 1 Method, it is characterised in that：The step of preparation method, is as follows：(1) weighed respectively according to weight proportion the bighead atractylodes rhizome, akebi, the coptis, Poria cocos, rhizoma alismatis, waxgourd peel, Divine Comedy, umbellate pore furgus, Asiatic plantain and Radix glycyrrhizae is crushed, and all passes through 100 mesh sieves respectively；(2) by the bighead atractylodes rhizome after sieving in step (1), akebi, the coptis, Poria cocos, rhizoma alismatis, waxgourd peel, Divine Comedy, umbellate pore furgus, Asiatic plantain and Radix glycyrrhizae is put into blending tank, is sufficiently mixed uniformly, that is, the Chinese medicine composition for the escherichia coli of piglets type stomach and intestine oedema that obtains medical treatment Finished product.
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| CN201711066772.5A CN107648398A (en) | 2017-11-03 | 2017-11-03 | Treat the Chinese medicine composition of escherichia coli of piglets type stomach and intestine oedema |
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| CN201711066772.5A CN107648398A (en) | 2017-11-03 | 2017-11-03 | Treat the Chinese medicine composition of escherichia coli of piglets type stomach and intestine oedema |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108578525A (en) * | 2017-12-29 | 2018-09-28 | 湖南惠生农业科技开发股份有限公司 | A kind of Chinese medicine composition and feed and preparation method thereof of prevention hydropsy for baby pigs |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102784306A (en) * | 2012-08-31 | 2012-11-21 | 山东新希望六和集团有限公司 | Traditional Chinese medicine composition and feed for treating piglet edema disease and preparation methods of traditional Chinese medicine composition and feed |
| CN105641260A (en) * | 2014-11-11 | 2016-06-08 | 天津中敖生物科技有限公司 | Traditional Chinese medicinal composition for treating piglet edema disease and preparation method of traditional Chinese medicinal composition |
-
2017
- 2017-11-03 CN CN201711066772.5A patent/CN107648398A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102784306A (en) * | 2012-08-31 | 2012-11-21 | 山东新希望六和集团有限公司 | Traditional Chinese medicine composition and feed for treating piglet edema disease and preparation methods of traditional Chinese medicine composition and feed |
| CN105641260A (en) * | 2014-11-11 | 2016-06-08 | 天津中敖生物科技有限公司 | Traditional Chinese medicinal composition for treating piglet edema disease and preparation method of traditional Chinese medicinal composition |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108578525A (en) * | 2017-12-29 | 2018-09-28 | 湖南惠生农业科技开发股份有限公司 | A kind of Chinese medicine composition and feed and preparation method thereof of prevention hydropsy for baby pigs |
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