CN108578525A - A kind of Chinese medicine composition and feed and preparation method thereof of prevention hydropsy for baby pigs - Google Patents
A kind of Chinese medicine composition and feed and preparation method thereof of prevention hydropsy for baby pigs Download PDFInfo
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- CN108578525A CN108578525A CN201711472038.9A CN201711472038A CN108578525A CN 108578525 A CN108578525 A CN 108578525A CN 201711472038 A CN201711472038 A CN 201711472038A CN 108578525 A CN108578525 A CN 108578525A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/83—Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
- A61K36/835—Aquilaria
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/20—Animal feeding-stuffs from material of animal origin
- A23K10/22—Animal feeding-stuffs from material of animal origin from fish
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
- A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
Abstract
The present invention discloses a kind of feed for preventing the Chinese medicine composition and its preparation of hydropsy for baby pigs, by the pathogenesis for being purposefully directed to hydropsy for baby pigs, utilize the use of the chemicals such as Chinese herbal medicine substitute antibiotics, effectively prevent the generation of hydropsy for baby pigs, and effectively treat illness piglet, case fatality rate is reduced, pigling immunity is improved, improves the pipe intestinal digesting function of piglet.
Description
Technical field
The invention belongs to formula for pig forage technical fields, and in particular to for prevent hydropsy for baby pigs Chinese medicine composition and
Feed and preparation method thereof.
Background technology
Hydropsy for baby pigs also known as piglet stomach and intestine oedema, are the one kind for causing weanling pig by the toxin of pathogenic Escherichia coli
Acute sporadic disease, the toxin generated by enteropathogenic E. Coli cause.With palpebral edema, ataxia, convulsions, paralysis,
The oedema such as stomach wall, mesenterium are characterized when calling hoarse and dissect.It is prominent that the disease mostly occurs in late fall in early spring, temperature cataclysm, feed
When so converting and turn group, delactational piglets are taken place mostly in, are fallen ill especially with the piglet fast, in good condition of growth in 5~15 days after wean
It is most common.The disease incidence is 5-30%, and lethality is up to 90% or more, pathogenesis be protect after piglet ablactation piglet from
The maternal antibody of pathogenic bacteria invasion gradually decreases, and the ability that enteron aisle resists bacteria planting declines, while because feed changes, making to cause a disease
Property Escherichia coli mass propagation, and be attached on intestinal wall by colonization factor, generate one or more of enterotoxins, enterotoxin with
Receptor on vascular endothelial cell and smooth muscle cell combines, and the protein of target cell is hindered synthesize, cause the denaturation of cell with
Necrosis causes vasopermeability to increase, and intravascular macromolecular substances enter tissue, so that tissue infiltration pressure is sharply increased, hydrone
Largely enter, eventually causes the oedema lesion of tissue.
The drug for the treatment of hydropsy for baby pigs is mostly Western medicine such as kanamycin sulfate injection liquid at present, although there is therapeutic effect,
But therapeutic effect unobvious, and can only just be treated when symptom to be found, prevention, and antibiotic cannot be played the role of
There is medicament residue in class drug.
Have many trials and prevents and treats hydropsy for baby pigs using traditional Chinese medicine in feed.
For example, Chinese patent CN201210318267.6 discloses a kind of Chinese traditional medicine composition for treating hydropsy for baby pigs
Object, feed and preparation method, wherein Chinese medicine composition include plantain seed, akebi, motherwort, the stem of noble dendrobium, red bean, umbellate pore furgus, winter
Melon skin, rhizoma alismatis, rhizome of cyrtomium, paris polyphylla, gymnema sylvestre, Fructus Corni, radix rehmanniae preparata, matrimony vine and root of Chinese trichosanthes.Achieve cure rate height, quick, nothing
Toxic side effect does not easily cause the advantageous effect of medicament residue etc..
Chinese patent CN201710640420.X discloses a kind of Chinese medicine additive that treating bowel oedema disease and its preparation side
Method is raw material by using folium artemisiae argyi, Asian puccoon, acupuncture needle head, wild honeysuckle, China pink grass, lychee leaf, paper mulberry bark, matrimony vine and motherwort, leads to
Rational proportion design is crossed, in conjunction with the regulation and control of technological parameter, so that the effect of collaboration is formed between drug, it can be effective
Treatment bowel oedema disease, treatment cycle is short, and treatment cost is low, and can also improve the immunocompetence of pig so that the disease-resistant energy of pig
Power is reinforced, while improving the gastrointestinal function of pig so that pig improves the utilization rate of feed, reduces feedstuff-meat ratio, improves economic effect
Benefit.
However, the Chinese medicine composition of above-mentioned patent needs to handle medicine in such a way that even traditional boiling is alcohol extracting
Object, since the special odor of Chinese medicine causes piglet not eat the feed containing such drug substantially.And the Chinese medicine of above-mentioned patent is matched
In place of 5 Shortcomings, for prevention hydropsy for baby pigs, the effect is unsatisfactory.
Present inventors have also extensively studied the pathogenesis of hydropsy for baby pigs, propose in a kind of prevention hydropsy for baby pigs newly
Medicine composition.
Invention content
The present invention is directed to overcome the deficiencies of the prior art and provide it is a kind of for prevent hydropsy for baby pigs Chinese medicine composition and
Its feed prepared utilizes the chemistry such as Chinese herbal medicine substitute antibiotics by being purposefully directed to the pathogenesis of hydropsy for baby pigs
The use of drug effectively prevents the generation of hydropsy for baby pigs, and effectively treatment illness piglet, reduces case fatality rate, improve piglet
Immunity improves the pipe intestinal digesting function of piglet.
In order to achieve the above object, the present invention provides a kind of for preventing the Chinese medicine composition of hydropsy for baby pigs, including with
Lower traditional Chinese medicinal components：Agalloch eaglewood, the root of three-nerved spicebush, Poria cocos, cup chrysanthemum, Chinese Fevervine Herb and crowndaisy chrysanthemum.
In some embodiments, the Chinese medicine composition includes the traditional Chinese medicinal components of following mass fraction：Agalloch eaglewood 5~15,
The root of three-nerved spicebush 5~15, Poria cocos 20~40, cup chrysanthemum 10~30, Chinese Fevervine Herb 5~15 and crowndaisy chrysanthemum 5~25.
Preferably, the Chinese medicine composition includes the traditional Chinese medicinal components of following mass fraction：Agalloch eaglewood 10, the root of three-nerved spicebush 10, Poria cocos 30,
Cup chrysanthemum 20, Chinese Fevervine Herb 10 and crowndaisy chrysanthemum 20.
In another aspect of this invention, a kind of feeding for preventing hydropsy for baby pigs comprising the Chinese medicine composition is provided
Material, the feed further includes feed pre-mixing material.
The feed pre-mixing material includes one in milk powder, corn, dregs of beans, fish meal, wheat bran, soya-bean oil, amino acid and minerals
Kind is a variety of.
According to another aspect of the invention, a kind of method preparing the feed for being used to prevent hydropsy for baby pigs is provided,
Include the following steps：1) the traditional Chinese medicinal components broken wall is ground into the particle of 200-300 mesh；2) particle is uniformly mixed
Afterwards, it is added in feed pre-mixing material by a certain percentage；3) it is blended with the feed pre-mixing material granulation of the Chinese medicine composition, is obtained
The feed.
Preferably, additive amount of the Chinese medicine composition in feed is 0.5~5%, preferably 1.0~1.2%, with quality
Percentage meter.
Preferably, the pelleting temperature of the feed pre-mixing material is controlled at 80 degrees Celsius or less.
Certainly, those skilled in the art can also be by way of mixing the Chinese medicine composition of the present invention with other feeds
Voluntarily prepare.
The present invention also provides it is a kind of for prevent hydropsy for baby pigs feed application method, wherein the feed applications in
The swinery for hydropsy for baby pigs occur takes the whole mode added or pulsed is added.
Research finds that the cause of disease of hydropsy for baby pigs is immunity degradation after piglet ablactation, while foodstuff changes and causes
Gastrointestinal function is inadaptable, and enteropathogenic E. Coli is colonized in enteron aisle, and the enterotoxin of release causes vascular permeability to sexually revise to be made
At.
For above-mentioned pathogenesis, the present invention is matched using agalloch eaglewood, the root of three-nerved spicebush, Poria cocos, cup chrysanthemum, Chinese Fevervine Herb and crowndaisy chrysanthemum Six-element Chinese medicine
5, promoting qi circulation and relieving pain, warming kidney for dispelling cold, eliminating dampness and diuresis is clearing heat and detoxicating, and dehumidify diuresis, swelling and pain relieving, and mild taste can either reconcile
Stomach prevents oedema, and the inducing diuresis to remove edema that can detoxify, and effectively treats hydropsy for baby pigs, obtains extraordinary effect.
In the Chinese medicine composition of the present invention, agalloch eaglewood promoting qi circulation and relieving pain, warming middle energizer to arrest vomiting, gas of receiving relievings asthma；Root of three-nerved spicebush promoting qi circulation and relieving pain, temperature
Kidney cold dispelling；Poria cocos eliminating dampness and diuresis, beneficial spleen and stomach, antitoxic heart-soothing and sedative；Cup chrysanthemum is clearing heat and detoxicating, anti-inflammation hemostasia, and dehumidify diuresis, desinsection；Chicken
Dung rattan expelling wind and activating blood flow, analgesic antidotal, promoting digestion, dehumidification swelling；Crowndaisy chrysanthemum and taste, profit two just, drink by dissolving phlegm, and is rich in a variety of ammonia
Base acid.
By above-mentioned compatibility, Chinese medicine composition of the invention can effectively treat hydropsy for baby pigs, with promoting qi circulation and relieving pain, clearly
The effect of hot anti-inflammatory, removing toxic substances inducing diuresis to remove edema；And the gastrointestinal function of piglet can be improved, immunity is improved, is effectively substituted anti-
Raw element.
Compared with prior art, beneficial effects of the present invention are：
The present invention considers the pathogenesis of physilogical characteristics and oedema after piglet ablactation, by ingenious compatibility,
Realize following effect：
1, the generation of hydropsy for baby pigs is prevented and treated, the piglet death rate is significantly reduced；
2, improve piglet digestive function, improve piglet speed of growth；
3, the disease resistance ability of domestic animal pig body is improved, immunizing potency function is improved；
4, treatment oedema reaches ecological, environmental protective effect, saves feeding cost, growth promotion is excellent without adding any antibiotic
Gesture is apparent；
5, the directly broken rear and feed premix of Chinese medicine composition is mixed with feed, and feed taste is easy to be connect by piglet
By not interfering with piglet food-intake.
Specific implementation mode
Embodiment 1- prepares the Chinese medicine composition for preventing hydropsy for baby pigs
Weigh following weight traditional Chinese medicinal components：Agalloch eaglewood 1kg, root of three-nerved spicebush 1kg, Poria cocos 3kg, cup chrysanthemum 2kg, Chinese Fevervine Herb 1kg and crowndaisy chrysanthemum
2kg.The traditional Chinese medicinal components broken wall is ground into the particle of 200-300 mesh using Chinese medicine wall cell disruption machine, mixing obtains the present invention's
Chinese medicine composition for preventing hydropsy for baby pigs.
Embodiment 2- prepares the feed for preventing hydropsy for baby pigs
Prepare feed premix, come from Changde Hui Shengjiuding Food Co., Ltd, the feed premix includes corn, beans
The dregs of rice, fish meal, wheat bran, soya-bean oil, core material, amino acid and several mineral materials.
According to the ratio that Chinese medicine composition additive amount is 1.2wt%, by the Chinese medicine composition and feed premix of embodiment 1
Mixing, is granulated at 75 DEG C, the feed for preventing hydropsy for baby pigs is made.
Contrast experiment
The child care pig swinery of one initial oedema is tested, delactational piglets at the beginning of choosing 600, according to age in days, body
The identical principle of weight, health status, sex ratio is grouped at random, is divided into a control group and 1 experimental group, every group of 300 sons
Pig.The feed of the continuous 30 days feeding embodiments 2 of experimental group, the commercially available nursery-stage pig feed of the continuous 30 days feedings of control group and to morbidity
Piggy injection kanamycin sulfate injection liquid.Experimental group and control group daily health caring according to identical pig farm child care scheme into
Row.
Experimental data is as shown in table 1：
Table 1：The influence that the feed of prevention hydropsy for baby pigs cultivates child care pig
The experimental results showed that：1) experimental group does not have that new case occurs again during feeding, and the neopathy rate of control group
Reach about 10%, shows that the feed of the Chinese medicine composition containing the present invention can effectively prevent hydropsy for baby pigs, improve piglet
Immunity；2) death rate of the morbidity piglet of experimental group is only 25%, and control group is treated using kanamycin sulfate injection liquid
The death rate reach 56.2%, show that the feed of Chinese medicine composition containing the present invention can effectively treat hydropsy for baby pigs, show
Writing reduces the piglet death rate, and the effect for treating hydropsy for baby pigs is better than antibiotic；3) experimental group feeds 30 days average weights
It is apparently higher than control group, shows that the feed of the Chinese medicine composition containing the present invention can improve the pipe intestinal digesting function of domestic animal pig,
Promote nutrient absorption, improves piglet speed of growth；Show the taste of traditional Chinese medicine unobvious of feed of the present invention simultaneously, will not cause piglet into
Appetite declines, and can promote piglet speed of growth instead.
It is real accordingly as it can be seen that the Chinese medicine composition for being used to prevent hydropsy for baby pigs and feed of the present invention are by ingenious compatibility
Show the generation of prevention and treatment hydropsy for baby pigs, significantly reduces the piglet death rate；Improve piglet digestive function, improves piglet life
Long speed；The disease resistance ability of domestic animal pig body is improved, immunizing potency function is improved；Effectively treatment oedema is appointed without addition
What antibiotic reaches ecological, environmental protective effect, saves feeding cost, and growth promotion is with the obvious advantage；Feed does not have apparent Chinese medicine peculiar smell, raises
Material mouth taste is easy to be received by piglet, does not interfere with the remarkable efficacies such as piglet food-intake.The Chinese medicine composition and its feed of the present invention
It can not only prevent and reduce the generation of hydropsy for baby pigs, improve piglet speed of growth, effectively treat hydropsy for baby pigs, moreover it is possible to break away from
Dependence of the current cultivation to chemicals such as antibiotic, reduces the use of chemicals, realizes the cultivation of ecological, environmental protective.
Those of ordinary skills in the art should understand that：The discussion of any of the above embodiment is exemplary only, not
It is intended to imply that the scope of the present disclosure (including claim) is limited to these examples；Under the thinking of the present invention, above example
Or can also be combined between the technical characteristic in different embodiments, and there are different aspects present invention as described above
Many other variations, in order to it is concise they do not provided in details.Therefore, all within the spirits and principles of the present invention,
Any omission, modification, equivalent replacement, improvement for being made etc., should all be included in the protection scope of the present invention.
Claims (9)
1. a kind of Chinese medicine composition raised for sow postpartum, which is characterized in that including following traditional Chinese medicinal components：Agalloch eaglewood, the root of three-nerved spicebush,
Poria cocos, cup chrysanthemum, Chinese Fevervine Herb and crowndaisy chrysanthemum.
2. Chinese medicine composition as described in claim 1, which is characterized in that include the traditional Chinese medicinal components of following mass fraction：Agalloch eaglewood 5
~15, the root of three-nerved spicebush 5~15, Poria cocos 20~40, cup chrysanthemum 10~30, Chinese Fevervine Herb 5~15 and crowndaisy chrysanthemum 5~25.
3. Chinese medicine composition as described in claim 1, which is characterized in that the Chinese medicine composition includes following mass fraction
Traditional Chinese medicinal components：Agalloch eaglewood 10, the root of three-nerved spicebush 10, Poria cocos 30, cup chrysanthemum 20, Chinese Fevervine Herb 10 and crowndaisy chrysanthemum 20.
4. a kind of feed for preventing hydropsy for baby pigs, which is characterized in that comprising as in any one of claims 1 to 3
Drug composition and feed pre-mixing material.
5. feed as claimed in claim 4, which is characterized in that the feed pre-mixing material include milk powder, corn, dregs of beans, fish meal,
It is one or more in wheat bran, soya-bean oil, amino acid and minerals.
6. feed as claimed in claim 5, which is characterized in that additive amount of the Chinese medicine composition in the feed be
0.5~5%, it is calculated in mass percent.
7. a kind of preparation method as claimed in claim 4 for preventing the feed of hydropsy for baby pigs, includes the following steps：
1) each traditional Chinese medicinal components broken wall of the Chinese medicine composition is ground into the particle of 200-300 mesh；
2) after evenly mixing by the particle of each traditional Chinese medicinal components, it is added to by a certain percentage in the feed pre-mixing material；It 3) will mixing
There is the feed pre-mixing material of the Chinese medicine composition to pelletize, obtains the feed for preventing hydropsy for baby pigs.
8. the method for claim 7, which is characterized in that the pelleting temperature of the granulation step 3 is controlled at 80 degrees Celsius
Below.
9. a kind of application method as claimed in claim 4 for preventing the feed of hydropsy for baby pigs, which is characterized in that described
Feed is applied to the swinery for hydropsy for baby pigs occur, takes the whole mode added or pulsed is added.
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Application publication date: 20180928 |