CN111544540A - Medicine for resisting novel coronavirus, preparation method and application thereof - Google Patents

Medicine for resisting novel coronavirus, preparation method and application thereof Download PDF

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CN111544540A
CN111544540A CN202010338859.9A CN202010338859A CN111544540A CN 111544540 A CN111544540 A CN 111544540A CN 202010338859 A CN202010338859 A CN 202010338859A CN 111544540 A CN111544540 A CN 111544540A
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parts
medicine
novel coronavirus
camphor
herb
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冼茂忠
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Foshan Aiting Electric Appliance Co ltd
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Foshan Aiting Electric Appliance Co ltd
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    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
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Abstract

The invention relates to a medicine for resisting the new coronavirus, its preparation method and its application, said medicine is calculated according to the part by weight, include herba Houttuyniae 20-30, rhizoma Coptidis 15-25, radix Stemonae 20-30, 15-25 of fructus forsythiae, 15-25 of radix Saposhnikoviae, 10-20 of herba Scutellariae Barbatae, fresh aloe 25-35, herba Ecliptae 10-20 and camphor 5-10; through the reasonable compatibility of the medicinal materials, the medicine has the functions of clearing away heat and toxic materials, resisting bacteria, fungi, viruses and the like, sterilizing and diminishing inflammation and improving the immunity of a human body, is beneficial to strengthening the physique of the human body, preventing and treating a novel coronavirus pneumonia patient infected at the early stage, and accelerating prognosis and disease outcome; the preparation method is simple and easy to realize; the medicine is atomized and then directly inhaled by a human body, directly contacts with germs, and then passes through the external high-temperature sauna environment to kill harmful germs in the environment, so that the inside and the outside are combined, and the treatment with high speed, high efficiency and low cost is achieved.

Description

Medicine for resisting novel coronavirus, preparation method and application thereof
Technical Field
The invention relates to the technical field of a medicine composition for resisting novel coronavirus, in particular to a medicine for resisting novel coronavirus, a preparation method and application thereof.
Background
2019, the novel coronavirus is abbreviated as 2019-nCoV, people infected with the virus have common signs of respiratory symptoms, fever, cough, breathlessness, dyspnea and the like, in more serious cases, the infection can cause pneumonia, severe acute respiratory syndrome, renal failure and even death, the lethality rate of the virus is about 2% -4%, the virus is mainly transmitted through respiratory droplets, contact transmission, aerosol and other ways, and after the people infected with the 2019-nCoV, the virus firstly affects the lung, shows that the lung is subjected to compaction, a large amount of exudation, infiltration of inflammatory cytokines, a large amount of infiltration of inflammatory cells and the like. Meanwhile, many secretions are seen in small bronchus, so that small gas passages are blocked, and gas exchange is influenced. The immune system is more heavily affected. Clinically, a very clear correlation between leukopenia, lymphopenia and disease progression and even death can be seen. The immunity is low, bacterial and fungal infection is easy to occur, but no specific treatment method for diseases caused by the novel coronavirus exists at present.
It is seen that improvements and enhancements to the prior art are needed.
Disclosure of Invention
In view of the defects of the prior art, the invention aims to provide a medicine for resisting the novel coronavirus, a preparation method and application thereof, and aims to solve the technical problem that the existing patient infected with the novel coronavirus can only resist the novel coronavirus through autoimmunity.
In order to achieve the purpose, the invention adopts the following technical scheme:
the medicine for resisting the novel coronavirus comprises the following components in parts by weight: 20-30 parts of houttuynia cordata, 15-25 parts of coptis chinensis, 20-30 parts of radix stemonae, 15-25 parts of fructus forsythiae, 15-25 parts of radix saposhnikoviae, 10-20 parts of sculellaria barbata, 25-35 parts of fresh aloe, 10-20 parts of eclipta and 5-10 parts of camphor.
The medicine for resisting the novel coronavirus also comprises the following components in parts by weight: 10-20 parts of dried ginger and 0.8-1.2 parts of antibiotic.
In the anti-novel coronavirus medicine, the anti-novel coronavirus medicine comprises the following components in parts by weight: 25 parts of heartleaf houttuynia herb, 20 parts of coptis chinensis, 25 parts of radix stemonae, 20 parts of weeping forsythia, 20 parts of divaricate saposhnikovia root, 15 parts of barbed skullcap herb, 30 parts of fresh aloe, 15 parts of yerbadetajo herb, 15 parts of dried ginger, 6 parts of camphor and 1 part of antibiotic.
In the medicine for resisting the novel coronavirus, the antibiotic is a cephalosporin antibiotic.
In the medicine for resisting the novel coronavirus, the cephalosporin antibiotics are one of ceftazidime, cefixime and cefetamet pivoxil.
A preparation method of a novel coronavirus resistant medicament, which comprises the novel coronavirus resistant medicament; the preparation method comprises the following steps:
s1, weighing the houttuynia cordata, the coptis chinensis, the stemona root, the fructus forsythiae, the saposhnikovia divaricata, the barbed skullcap herb, the fresh aloe, the eclipta, the dried ginger, the camphor and the antibiotics in parts by weight respectively;
s2, adding houttuynia cordata, coptis chinensis, radix stemonae, fructus forsythiae, radix saposhnikoviae, herba scutellariae barbatae, fresh aloe, herba ecliptae and rhizoma zingiberis into water, decocting for 15-20 minutes, separating residues, cooling, sequentially adding camphor and antibiotics into filtrate, and stirring until the camphor and the antibiotics are dissolved to obtain the medicine.
In the preparation method of the novel coronavirus resistant drug, the temperature of the filtrate is 75-80 ℃ when camphor and antibiotics are added in the step S2; the volume of the prepared drug is 1000-1500 ml.
Use of an anti-neocoronavirus drug comprising nebulizing the prepared drug into a sauna room using one of a humidifier or nebulizer.
In the application of the novel coronavirus resistant drug, the temperature of the top of the sauna room is 65-70 ℃.
In the application of the novel coronavirus resistant medicine, the application is to prepare a medicine for improving the human immunity of a 2019-infected novel coronavirus patient.
Has the advantages that:
the invention provides a medicine for resisting novel coronavirus, a preparation method and application thereof, and the medicine has the functions of clearing away heat and toxic material, sterilizing and diminishing inflammation such as antibacterial, antifungal and antiviral and improving human immunity through reasonable compatibility of the medicinal materials, is beneficial to strengthening human body, preventing and treating patients infected with early novel coronavirus pneumonia, and accelerating prognosis and disease outcome; the atomized liquid is directly inhaled by a human body and directly contacted with germs, and then harmful germs in the environment are killed through the external high-temperature sauna environment, so that the inside and the outside are combined, and the quick, efficient and low-cost treatment is achieved.
Detailed Description
The invention provides a medicine for resisting novel coronavirus, a preparation method and application, and in order to make the purpose, technical scheme and effect of the invention clearer and clearer, the invention is further detailed by the following examples. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
The invention provides a medicine for resisting novel coronavirus, which comprises the following components in parts by weight: comprises 20-30 parts of heartleaf houttuynia herb, 15-25 parts of coptis, 20-30 parts of radix stemonae, 15-25 parts of weeping forsythia, 15-25 parts of divaricate saposhnikovia root, 10-20 parts of barbed skullcap herb, 25-35 parts of fresh aloe, 10-20 parts of yerbadetajo herb and 5-10 parts of camphor. Through the synergistic effect of the reasonable compatibility, the medicine has the functions of clearing away heat and toxic materials, resisting bacteria, fungi, viruses and the like, sterilizing and diminishing inflammation and improving the immunity of a human body, is favorable for enhancing the physique, preventing and treating patients infected with early novel coronavirus pneumonia, and quickens prognosis and disease outcome.
Further, the medicine for resisting the novel coronavirus also comprises the following components in parts by weight: 10-20 parts of dried ginger and 0.8-1.2 parts of antibiotic. On the basis of the medicines, the dried ginger in parts by weight is added for neutralizing the cold and cool of compatibility, so that discomfort caused by taking of people with cold and cool physique is avoided; trace antibiotic is added to enhance the bactericidal effect.
Specifically, the anti-novel coronavirus medicine comprises the following components in parts by weight: 25 parts of heartleaf houttuynia herb, 20 parts of coptis chinensis, 25 parts of radix stemonae, 20 parts of weeping forsythia, 20 parts of divaricate saposhnikovia root, 15 parts of barbed skullcap herb, 30 parts of fresh aloe, 15 parts of yerbadetajo herb, 15 parts of dried ginger, 6 parts of camphor and 1 part of antibiotic.
Houttuynia cordata: centario Sibiricum (Wuyue spring and autumn), houttuynia cordata (Bie Biao), potamogeton crispus (Tang Ben Cao), houttuynia cordata (Meng), houttuynia cordata (Fo rock Ben Cao), houttuynia cordata (Ji Yi Fang), potamogeton crispus (compendium), Clerodendron trichotomum (Jialin Co., Ltd.), Pleurotus ostreatus (Zun Fu Zhi), pig nostril (Tian Bao Ben Cao), Jijiuxian (Ling nan Cao Yao (Ling Yang Yao Co., Ltd.), heavy drugs, Caraway clavulifera (modern practical Chinese medicine), Cibotium barometz (Guangzhou Yao Yi Xue Yao Wu Yang Yao Wu Zhong Yao Yang Yao Zhi Xue Cao (Gui Zhong Yao Zhong Yao Xue Cao Wan, Qin Zhu Yao Yang Cao Zhong Yao Wan Zhong Zi Cao Wan Cao (Jian, stinky wormwood (Ben Cao of Quanzhou), clerodendrum bungei, laggera pterodonta, pungent litse fruit, milk hair grass (J. Don pharmaceutical record of Hunan), herb, tangerine peel and houttuynia cordata (Ben Cao of Min Dong). The name of the prescription: houttuynia cordata, houttuynia cordata and herba houttuyniae. Yu xing Cao is pungent in flavor and cold in nature and enters lung meridian. Has effects in clearing away heat and toxic materials, relieving swelling, treating sore, promoting urination, removing dampness, clearing away heat, relieving dysentery, invigorating stomach, and promoting digestion, and can be used for treating lung abscess, pyocutaneous disease, hemorrhoid hematochezia, and heat accumulation in spleen and stomach due to excess heat, heat toxin, dampness, and disease heat; can be used for treating lobar pneumonia, acute bronchitis, enteritis, and diarrhea; fructus forsythiae is added to treat toxic pneumonia; the cordate houttuynia decoction has different degrees of inhibition effects on various gram positive bacteria and negative bacteria such as staphylococcus aureus, staphylococcus albus, hemolytic streptococcus, pneumococcus, catacoccus, diphtheria bacillus, proteus bacillus, shigella, fuwensis and shigella sonnei, enteritis bacillus and the like, and the effective component decanoyl acetaldehyde has obvious antibacterial effects on various bacteria, acid-fast bacillus, fungi and the like; in addition, the houttuynia cordata has the antiviral effect and is realized by inhibiting the activity of transcription factors required by virus replication; the houttuynia cordata decoction can obviously promote the ability of human peripheral blood leukocytes to phagocytose staphylococcus aureus in vitro, synthesize houttuynine sodium bisulfite, improve the phagocytic function of the leukocytes of patients with chronic tracheitis, improve the serum properdin level of the patients and improve the immunity of organisms; flavonoid compounds such as quercetin, quercitrin, isoquercitrin and the like contained in the houttuynia cordata also have remarkable anti-inflammatory effect, and can remarkably inhibit capillary hyperfunction at the early stage of inflammation; therefore, the houttuynia cordata has the effects of resisting bacteria and viruses, improving immunity, resisting inflammation, promoting urination and the like.
Coptis chinensis: wang Lian and Zhi Lian. Firstly, the flavor is even named: chuanlian (Bencao Meng quan), Jizhan Lian, Jizhan Huang, Guang Lian. ② Yalian (Ben Cao Yuan Xin) also named: cilian emei, Jiading lian and Cigailian. ③ Ye Huanglian is named: the phoenix tail is connected. Yunlian (rhizoma Coptidis ), Chuan Huanglian. Coptis root, rhizoma Coptidis, with bitter and cold nature, enters heart, spleen, stomach, liver, gallbladder and large intestine meridians; bitter taste is a turbid yin medicine, bitter and cold can reduce fire heat, can purge fire, eliminate dampness, detoxify and kill parasites, the bitter and cold can purge taiyin lung and spleen and remove damp-heat, and can reduce fire heat of three yin to remove toxicity, heat toxin is generated during treatment, typhoid fever, severe heat, vexation, fullness and vomiting, bacillary dysentery, heat diarrhea abdominal pain, lung nodule pressing, vomiting, epistaxis, bleeding, thirst quenching, malnutrition, ascariasis, whooping cough, sore throat, hot eyes, aphtha, carbuncle, ulcer, eczema and scald caused by hot water. The traditional Chinese medicine composition is clinically used for treating diseases such as bacillary dysentery, typhoid fever, phthisis, epidemic cerebrospinal meningitis, lobar pneumonia, scarlet fever, diphtheria, lung abscess, empyema, ulcerative colitis, hypertension, brucellosis, pulmonary candidiasis, balantidosis coli, measles, pertussis, burn, anal fissure, osteoarticular tuberculosis sinus, gynecological diseases, ophthalmic diseases, suppurative otitis media, atrophic rhinitis, angina, acute tonsillitis, maxillary sinusitis, root canal diseases, oral and maxillofacial inflammation, skin cancer inflammation, eczema, and various exudative erythema.
Stemona root: cough medicine (Taoyhongjing), BAIGEN, radix asparagi, BANAI (Young's experience prescription), JIUJUGEN (herbal convenient prescription), JIUGENG (classified herbaceous medicine property), YIWUJI (Jiangsu herbal medicine record), ninety-nine GEN (Chinese soil pesticide record), SHANGBAOGEN (Chinese medicine record), and NIAOBING (Mindong herbal medicine record). Radix stemonae, also known as: stemona (fructus Kochiae), Borneo camphor (Japanese St. Ex Fr.) Pilat, and Stemona (radix Stemonae). Radix Stemonae is slightly warm in nature, sweet and bitter in taste, enters lung meridian, has effects of moistening lung, relieving cough and eliminating phlegm, belongs to cough and asthma relieving medicines classified under phlegm-eliminating cough and asthma relieving medicines, has curative effect on new and long-term cough such as pulmonary tuberculosis, pertussis, acute and chronic tracheitis, and can resist pathogenic microorganism. It is often combined with ginger juice to treat cough.
Fructus forsythiae: herba Ecliptae (treatise on herb Property), semen seu radix Kalopanacis Delavayi (Tang Ben Cao), and vacant shell (Chinese materia Medica). Forsythia, also known as: LIAN, YI QIAO (Elya), LANHUA, axletree terminal, herba Ardisiae Gigantifoliae, SANJIAO (Ben Jing), LIAO (uncut Guo Zhu in Erya), DAQIAO (Tang materia Medica), HUANGJIE, HUASHOUDAN, HUA petal, FANQIAO, and HUAHUA stripe. The name of the prescription: forsythia fruit, green forsythia fruit. Empty fructus forsythiae, old fructus forsythiae, (Lian Han, Lian Feng, Lian Chi); it is cold in nature and bitter in taste; it enters lung, heart and small intestine meridians. The fruit contains phillyrin, sterol compounds, saponin (without hemolytic activity), flavonol glycosides, and malpigenin. The pericarp contains oleanolic acid. The green forsythia contains 4.89% of saponin and 0.2% of alkaloid. Has the effects of clearing away heat and toxic materials, dispersing pathogenic accumulation, and relieving swelling. It can be used for treating warm heat, erysipelas, acute mastitis, macula, carbuncle, ulcer, toxic swelling, lymphoid tuberculosis, wind-heat type common cold, early stage epidemic febrile disease, fever, polydipsia, coma, macula, heat stranguria, and anuresis. Fructus forsythiae and Spica Prunellae have effects in dispersing pathogen accumulation and eliminating scrofula; matched with divaricate saposhnikovia root for treating infantile fever; fructus forsythiae has antibacterial effect in vitro, and can inhibit typhoid bacillus, paratyphoid bacillus, Escherichia coli, dysentery bacillus, diphtheria bacillus, Vibrio cholerae, staphylococcus, streptococcus, etc., and has better in vitro antibacterial effect with rhizoma Coptidis; fructus forsythiae also has effects in stopping vomiting, tonifying heart, and promoting urination; the traditional Chinese medicine composition is clinically used for treating lung abscess, acute nephritis, purpura, retinal hemorrhage and the like.
Wind prevention: herba Pileae Scriptae (Ben Jing), herba Foeniculi, Baizhi, BAIBU (WU Pu Ben Cao), Screen (Bie Lu), and herba Saussureae Involueratae (herbal materials Collection). Ledebouriella root, also known as: mountain celery and white hairy grass. Trade name: radix Saposhnikoviae, and radix Saposhnikoviae. The wind-proof flavor is pungent, sweet and warm; meridian tropism is classified into bladder, liver and spleen meridians. The functions are mainly used for relieving exterior syndrome, dispelling wind, eliminating dampness and relieving pain; it is used to treat wind-cold type common cold, headache, dizziness, stiff neck, arthralgia due to wind-cold-dampness, joint pain, spasm and spasm of limbs, and tetanus. Dispelling wind and relieving exterior syndrome; eliminating dampness and relieving pain; spasmolysis; relieving itching. Wind-cold affecting the exterior; headache and body pain; rheumatic arthralgia; joint soreness; abdominal pain and diarrhea; the intestinal wind gives the blood; tetanus; rubella with pruritus; beginning of ulcer; it has analgesic, tranquilizing, antiinflammatory, and antiallergic effects, and can inhibit bacteria of Staphylococcus aureus, beta hemolytic streptococcus, Diplococcus pneumoniae, and two kinds of fungi (Penicillium chrysogenum, Aspergillus versicolor).
The Chinese barbed skullcap herb has the alias: the traditional Chinese medicine composition comprises the following raw materials of general grass, eclipta alba (Nanjing folk medicinal grass), toothbrush grass (Jiangsu medicinal herb record), small Han Xin grass, water Han Xin (Guangxi medicinal herb record), small ear du grass (Nanning city medicinal herb record)), linearstripe skullcap root, golden du ear (Jiangxi folk medicinal herb empirical prescription), wild selfheal, fangcao, herb of common semiflower, herb of semiaquilegia, vervain, four-side grass (Zhejiang folk common herbal medicine record), ear du grass (Guangxi Chinese herbal medicine record), small Asian calendula, tiger red, recycled grass (Fujian Chinese herbal medicine record), Jianshanbian verbena (Chengdu common herbal medicine record) and narrow-leaf Tianzhan (Fujian new medical treatment record compilation). The barbed skullcap herb is pungent in flavor; bitter; cold in nature; meridian tropism entering lung; liver; the kidney channel. Mainly used for clearing away heat and toxic material; stasis dissipating and bleeding stopping; induce diuresis to alleviate edema. It can be used for treating heat and toxic materials, blood stasis, hemostasis, diuresis, detumescence, toxic heat, carbuncle, laryngopharynx pain, lung abscess, intestinal abscess, lymphoid tuberculosis, venomous snake bite, traumatic injury, hematemesis, epistaxis, bloody stranguria, ascites and cancer; it has inhibitory effect on Staphylococcus aureus, Shigella flexneri, typhoid bacillus, Pseudomonas aeruginosa, and Escherichia coli; the carthamin has strong effect in resisting smooth muscle contraction caused by histamine, and has good effects in eliminating phlegm, inhibiting tumor, and regulating immunity.
Fresh aloe is also called as follows: the classic of the Luo (treatise on drug Property) is the Bureau (supplement to materia Medica), the elephant gallbladder and Nodey (materia Medica of Kaibao), the Logwei (reserve of raw herb-property), also named: transparent aloe. Aloe is bitter in taste and cold in nature; it enters liver, stomach and large intestine meridians; the functions are mainly used for treating liver channel excess heat dizziness, headache, tinnitus, dysphoria, constipation, infantile convulsion, malnutritional stagnation, atrophic rhinitis and scrofula; it can be used together with Coptidis rhizoma to treat mania, irritability, palpitation, and convulsion due to excessive fire in liver meridian; the alcohol extract of Aloe has effect in inhibiting human type tubercle bacillus; it can inhibit the synthesis of bacterial nucleic acid, which results in inhibiting the synthesis of protein, and thus inhibiting the growth of bacteria, and its methanol extract can inhibit herpes simplex virus 1 and 2 in vitro; aloe has effects in resisting Escherichia coli and Pseudomonas aeruginosa; aloe polysaccharide has immunoregulatory activity.
And (3) eclipta: jinling grasses (Qianjin Oenothera biennis), lotus seeds grasses (Tang Ben Cao), eclipta alba (Ben draft Jing), white eclipta alba (crawler rock Ben Cao), monkey heads of Chinese roses (complete collections of things necessary for families), lotus grasses (Yunnan Ben Cao), herba phyllanthi (Zhen Xue Zheng Chuan Shu), tabacco, herba ecliptae and herba Swertiae Bimaculatae (compendium), white flower Wedelia chinensis (Linn nan Cao Yao Bing Yao (modern practical Chinese medicine), wild hydrangea (herbal material Association), plucked head Wu Tou, dripped Wu Jiang Jiangjiang river Chinese herbal handbook), water hyacinth (Jiangsu Yao Zhi Cao (Miao Hua Cao Wo Ya, golden silk anesthesia (survey of herbal medicine in Guizhou), Chinese ink and herbaceous plant (empirical prescription of folk herbal medicine in Jiangxi). The name of the prescription: ecliptae herba, and Ecliptae herba. The eclipta is sweet in nature, sour in taste and cold in nature; entering kidney and liver meridian; the functions are mainly used for nourishing liver and kidney, benefiting yin, cooling blood and stopping bleeding; can be used for treating odontoseisis, premature gray hair, giddiness, tinnitus, soreness of waist and knees, yin deficiency, blood heat, hematemesis, hemoptysis, epistaxis, hematuria, bloody dysentery, diphtheria, stranguria with turbid urine, metrorrhagia, metrostaxis, hemorrhage due to trauma, etc.; ecliptae herba also has antibacterial effect.
Rhizoma zingiberis also named as: white ginger, yujiang ginger and dried ginger (gang mu). The name of the prescription: dried ginger, fried ginger and dried ginger slices. The traditional Chinese medicine composition is mainly used for diminishing inflammation and sterilizing, coptis chinensis is bitter and cold, the spleen and the stomach are easily injured after long-term taking, sculellaria barbata, fresh aloe and eclipta are cold in nature, the compatibility is cold and cool, deficiency-cold symptoms are not suitable for excessive taking, but dried ginger is hot, pungent and strong in property, is good at warming yang of the spleen and the stomach, can warm lung and reduce phlegm, is clinically used for treating diseases such as deficiency-cold of middle jiao, yang deficiency and prostration, lung cough and asthma caused by cold drink, and is used for warming middle energizer to dispel cold, restoring yang to promote blood circulation, warming lung to resolve fluid retention, removing dislike and nourishing new, and plays a role in neutralization in the compatibility.
The name of camphor is: shaoyao brain (Shenxiao Fang), Chao brain (Pin Hui Jing Yao), brain (Ben Jing Yuan), Youyao brain, and Tree brain (Yao Wan). The camphor is pungent in flavor and warm in nature; entering heart and spleen meridians; the camphor has the functions of stimulating the cold receptors, locally anaesthetizing, relieving itching and easing pain, can excite the central nervous system, and is particularly obvious for the high-grade central nervous system; has cardiotonic effect on circulatory collapse or acute heart failure; and has slight phlegm-eliminating effect.
Further, the antibiotic is a cephalosporin antibiotic. Specifically, the cephalosporin antibiotics are ceftazidime (molecular formula is C)22H22N6O7S2) Cefixime (molecular formula is C)16H17N5O7S2) Cefetamet pivoxil (molecular formula C)20H25N5O7S2) One kind of (1). The cephalosporin antibiotics are preferably third-generation cephalosporin antibiotics, have wide antibacterial spectrum, and have antibacterial activity on partial gram-positive bacteria and partial gram-negative bacteriaThe third generation cephalosporin antibiotics have strong stability to β -lactamase produced by various bacteria, show excellent antibacterial power to β -lactamase producing bacteria and are basically nontoxic to kidneys, because the novel coronaviruses cause serious influence on the immune system of the human body after invading the human body, cause reduction in the total number of leukocytes and reduction in the count of lymphocytes, cause increase in peripheral blood inflammatory factors such as IL-6 and C-reactive protein, and the like, the human immunity is reduced, the cephalosporins antibiotics are very likely to cause infection of fungi, most of the cephalosporins antibiotics are used for killing bacteria and improving the human immunity, novel coronaviruses can prevent the bacteria, can alleviate the bacterial infection in the market, and are convenient to purchase, and are convenient to prepare and convenient to prepare medicines for oral administration, and are convenient to prepare medicines for treating the coronaviruses.
A preparation method of a novel coronavirus resistant medicament, which comprises the novel coronavirus resistant medicament; the preparation method comprises the following steps: respectively weighing the cordate houttuynia, the coptis chinensis, the stemona root, the fructus forsythiae, the radix sileris, the sculellaria barbata, the fresh aloe, the eclipta, the dried ginger, the camphor and the antibiotic in parts by weight; adding houttuynia cordata, coptis chinensis, stemona, fructus forsythiae, radix sileris, barbed skullcap herb, fresh aloe, yerbadetajo herb and dried ginger into 2000ml of 1500-fold water, decocting with strong fire for 15-20 minutes after the water is boiled, turning off the fire when the water amount in the kettle is 1500ml, filtering the dregs of a decoction, sequentially adding ground camphor and antibiotic when the filtrate is cooled to 75-80 ℃, and stirring until the camphor and the antibiotic are dissolved to obtain the medicine. Boiling with strong fire, decocting with slow fire for 15-20 minutes, adding the effective components of the medicinal materials into water, adding the ground camphor and antibiotics into the filtrate at 75-80 ℃, so that the problem that the antibiotics lose efficacy due to overhigh temperature during addition is avoided, the problem that the camphor and the antibiotics are not sufficiently melted during addition is avoided, and the drug effect is reduced. The preparation method is simple and convenient, has no difference with the ordinary medicine cooking method of people, and is easy to realize.
The application of the novel coronavirus resistant medicine comprises the steps of atomizing the prepared medicine into a sauna room with the top temperature of 65-70 ℃ by utilizing one of a humidifier or an atomizer, enabling the medicine to be directly acted on bacteria, fungi and viruses through the high-temperature environment of the sauna room and the medicine atomization to be inhaled into the lung through the respiratory tract of a person, and enabling the distance between the head of the human body and an atomizer tube to be 15-20 cm when the medicine is inhaled. Through the control at novel coronavirus morbidity early stage, reach effectual prevention effect, high temperature sauna can also promote people's health blood circulation, increases the endocrine and expels toxin, perspires, the hydrofuge etc to play the health care effect of reinforcing physique, improve human immunity, improve the ability of patient's immune system to confront novel coronavirus, use still to chronic rhinitis, chronic pharyngolaryngitis, facial skin nursing plays certain effect. Because high-temperature sauna is involved, the population needs to be divided into the following types: 1. healthy people; 2. people with basic diseases; 3. people with hypertension; 4. children, infants; 5. a pregnant woman; 6. the elderly population; the above people need to be reasonably adjusted according to their own physical conditions, and pregnant women are prohibited to use high-temperature sauna; children and infants need to be accompanied by adults; the hypertension can be only performed after the blood pressure of the hypertension group is regulated to be normal, and the hypertension is determined by the degree of disease of basic patients. The prepared medicine is taken for five days as a treatment course, the medicine which is not used temporarily is kept fresh and preserved, and the medicine is taken out for one time, so that the medicine is prevented from being polluted by the sharp increase of the number of bacteria after multiple heating, the curative effect of the medicine is prevented from being influenced, and the risk of respiratory diseases is increased; the refrigerated medicine is heated to 80-90 ℃ before being used each time, poured into a humidifier or an atomizer, and then used in combination with a sauna room, wherein the refrigerated medicine is used by healthy people of 18-65 years old 2 times a day, and is used once in the morning and at night, and each time is 15-20 minutes.
Further, the application is the application in the preparation of the medicine for improving the human immunity of the patient infected with the 2019 novel coronavirus. By adopting the medicine, the human immunity of a 2019-infected novel coronavirus patient is improved, the physique of the patient is enhanced, immune cells in the body of the patient can generate immune response, and the novel coronavirus can be eliminated.
The novel coronavirus resistant medicine is used for treating patients infected by various viruses or infected by low immunity and infected by wind, heat and damp toxin caused by wind, heat and damp toxin in vivo and patients infected by 2019 novel coronavirus with early symptoms; the patients infected with the 2019 novel coronavirus can be classified into early stage, middle stage and later stage according to the damage degree caused to the immune system of a human body, the medicament has curative effect on the patients with early symptoms, and the curative effect on the patients with middle and later stage symptoms is reduced or cannot reach the due curative effect; in addition, because sweet, greasy and spicy foods are the substances for supporting yang to generate heat and consuming body fluid to impair qi, patients with wind-fire and damp-heat should fast and cautiously eat sweet, greasy and spicy foods, and the patients can reduce the beneficial effects of the foods or can not achieve the due treatment effects of the foods if overeating, overeating and eating the sweet, greasy and spicy foods during the treatment period; in addition, a patient infected with the 2019 novel coronavirus should keep a pleasant mood, properly exercise and properly ingest high-protein foods, such as meat, fish, eggs and the like, so that the physique can be enhanced, and the prognosis is better by combining the use of the medicines.
Example 1
The medicine for resisting the novel coronavirus comprises the following components in parts by weight: 25 parts of heartleaf houttuynia herb, 15 parts of coptis chinensis, 30 parts of radix stemonae, 25 parts of weeping forsythia, 20 parts of divaricate saposhnikovia root, 20 parts of barbed skullcap herb, 25 parts of fresh aloe, 15 parts of yerbadetajo herb, 15 parts of dried ginger, 8 parts of camphor and 1.2 parts of ceftazidime.
A preparation method of an anti-novel coronavirus medicine comprises the following steps: respectively weighing the cordate houttuynia, the coptis chinensis, the stemona root, the forsythia, the divaricate saposhnikovia root, the barbed skullcap herb, the fresh aloe, the yerbadetajo herb, the dried ginger, the camphor and the ceftazidime in parts by weight; adding houttuynia cordata, coptis chinensis, radix stemonae, fructus forsythiae, radix sileris, barbed skullcap herb, fresh aloe, yerbadetajo herb and dried ginger into 1500ml of water, boiling the mixture with strong fire, decocting the mixture for 18 minutes with slow fire until the water content in the pot is 1000-1500ml, separating slag, cooling, sequentially adding camphor and ceftazidime into filtrate at the temperature of 75-80 ℃, and stirring the mixture until the mixture is dissolved to obtain the medicine.
Example 2
The medicine for resisting the novel coronavirus comprises the following components in parts by weight: 20 parts of heartleaf houttuynia herb, 20 parts of coptis chinensis, 25 parts of radix stemonae, 15 parts of weeping forsythia, 25 parts of divaricate saposhnikovia root, 15 parts of barbed skullcap herb, 35 parts of fresh aloe, 15 parts of yerbadetajo herb, 10 parts of dried ginger and 10 parts of camphor.
A preparation method of an anti-novel coronavirus medicine comprises the following steps: respectively weighing the cordate houttuynia, the coptis chinensis, the stemona root, the fructus forsythiae, the radix sileris, the sculellaria barbata, the fresh aloe, the eclipta, the dried ginger and the camphor in parts by weight; adding houttuynia cordata, coptis chinensis, radix stemonae, fructus forsythiae, radix sileris, barbed skullcap herb, fresh aloe, yerbadetajo herb and dried ginger into 1500ml of water, boiling the mixture with strong fire, decocting the mixture for 15 minutes with slow fire until the water amount in the pot is 1000-1500ml, separating slag, cooling, sequentially adding camphor into filtrate at the temperature of 75-80 ℃, and stirring the mixture until the camphor is dissolved to obtain the medicine.
Example 3
The medicine for resisting the novel coronavirus comprises the following components in parts by weight: 30 parts of heartleaf houttuynia herb, 25 parts of coptis chinensis, 20 parts of radix stemonae, 20 parts of weeping forsythia, 15 parts of divaricate saposhnikovia root, 10 parts of barbed skullcap herb, 25 parts of fresh aloe, 10 parts of yerbadetajo herb, 20 parts of dried ginger, 5 parts of camphor and 0.8 part of cefetamet pivoxil.
A preparation method of an anti-novel coronavirus medicine comprises the following steps: respectively weighing the cordate houttuynia, the coptis chinensis, the stemona root, the forsythia, the divaricate saposhnikovia root, the barbed skullcap herb, the fresh aloe, the yerbadetajo herb, the dried ginger, the camphor and the cefetamet pivoxil in parts by weight; adding houttuynia cordata, coptis chinensis, radix stemonae, fructus forsythiae, radix sileris, barbed skullcap herb, fresh aloe, yerbadetajo herb and dried ginger into 2000ml of water, boiling the mixture with a strong fire, decocting the mixture for 20 minutes with a slow fire until the water amount in the pot is 1000-1500ml, separating slag, cooling the mixture, sequentially adding camphor and cefetamet pivoxil into the filtrate at the temperature of 75-80 ℃, and stirring the mixture until the mixture is dissolved to obtain the medicine.
Example 4
The medicine for resisting the novel coronavirus comprises the following components in parts by weight: 25 parts of heartleaf houttuynia herb, 20 parts of coptis chinensis, 30 parts of radix stemonae, 20 parts of weeping forsythia, 15 parts of divaricate saposhnikovia root, 15 parts of barbed skullcap herb, 30 parts of fresh aloe, 20 parts of yerbadetajo herb, 6 parts of camphor and 1 part of cefixime.
A preparation method of an anti-novel coronavirus medicine comprises the following steps: respectively weighing the cordate houttuynia, the coptis chinensis, the stemona root, the forsythia, the divaricate saposhnikovia root, the barbed skullcap herb, the fresh aloe, the yerbadetajo herb, the camphor and the cefixime in parts by weight; adding houttuynia cordata, coptis chinensis, radix stemonae, fructus forsythiae, radix sileris, barbed skullcap herb, fresh aloe and yerbadetajo herb into 2000ml of water, boiling the mixture with a big fire, decocting the mixture for 15 minutes with a small fire until the water amount in the pot is 1000-1500ml, separating dregs, cooling, sequentially adding camphor and cefixime into filtrate at the temperature of 75-80 ℃, and stirring the mixture until the mixture is dissolved to obtain the medicine.
Respectively selecting 10 (3 ages are 18-20, 3 ages are 28-30, 2 ages are 50-52 and 2 ages are 65-70) normal healthy people, 10 chronic rhinitis patients (5 chronic simple rhinitis, 3 medical histories are 3-5, 2 medical histories are 8-10, 5 chronic hypertrophic rhinitis, 2 medical histories are 3-5, 2 medical histories are 6-7, 1 medical history is more than 10) and 10 chronic pharyngolaryngitis patients (5 chronic simple pharyngitis, 1 medical history is 2, 2 medical history is 3-5, 2 medical history is more than 10, 5 chronic hypertrophic pharyngitis, 2 medical history is 3-5, 2 medical history is more than 10) to atomize the medicine prepared in the embodiment 1-4, inhaling orally and nasally at the same time 15-20 cm away from the head, and treating in sauna room at the top temperature of 65-70 deg.C for 15-20 min 2 times a day, all with good effect; the number of sneezing of the chronic rhinitis patient in the early period is greatly reduced, the probability of nasal obstruction is reduced, the smell is recovered, and nasal secretion is reduced; the symptoms of discomfort, dry itching, distending pain, foreign body sensation, cough, expectoration and the like of the throat of the patient with chronic pharyngolaryngitis are relieved.
In conclusion, the invention adopts the reasonable compatibility of the medicines and the antibiotic to enhance the sterilization effect, atomizes the medicines, directly inhales the medicines through a human body, directly contacts with pathogenic bacteria, and then kills harmful pathogenic bacteria in the environment through the external high-temperature sauna environment, so that the internal and external combination is realized, the fast, efficient and low-cost treatment is achieved, the body fluid circulation is accelerated, and the toxin is eliminated, thereby playing the roles of enhancing the physique and improving the immunity.
It should be understood that equivalents and modifications of the technical solution and inventive concept thereof may occur to those skilled in the art, and all such modifications and alterations should fall within the scope of the appended claims.

Claims (10)

1. The medicine for resisting the novel coronavirus is characterized by comprising the following components in parts by weight: 20-30 parts of houttuynia cordata, 15-25 parts of coptis chinensis, 20-30 parts of radix stemonae, 15-25 parts of fructus forsythiae, 15-25 parts of radix saposhnikoviae, 10-20 parts of sculellaria barbata, 25-35 parts of fresh aloe, 10-20 parts of eclipta and 5-10 parts of camphor.
2. The anti-neocoronavirus drug according to claim 1, further comprising the following components in parts by weight: 10-20 parts of dried ginger and 0.8-1.2 parts of antibiotic.
3. The anti-neocoronavirus agent according to claim 1, wherein the anti-neocoronavirus agent comprises the following components in parts by weight: 25 parts of heartleaf houttuynia herb, 20 parts of coptis chinensis, 25 parts of radix stemonae, 20 parts of weeping forsythia, 20 parts of divaricate saposhnikovia root, 15 parts of barbed skullcap herb, 30 parts of fresh aloe, 15 parts of yerbadetajo herb, 15 parts of dried ginger, 6 parts of camphor and 1 part of antibiotic.
4. The agent against novel coronaviruses according to claim 3, wherein the antibiotic is a cephalosporin antibiotic.
5. The agent for treating a novel coronavirus according to claim 4, wherein the cephalosporin antibiotic is one of ceftazidime, cefixime and cefetamet pivoxil.
6. A method for producing an anti-novel coronavirus drug, which comprises the anti-novel coronavirus drug according to any one of claims 1 to 5; the preparation method comprises the following steps:
s1, weighing the houttuynia cordata, the coptis chinensis, the stemona root, the fructus forsythiae, the saposhnikovia divaricata, the barbed skullcap herb, the fresh aloe, the eclipta, the dried ginger, the camphor and the antibiotics in parts by weight respectively;
s2, adding houttuynia cordata, coptis chinensis, radix stemonae, fructus forsythiae, radix saposhnikoviae, herba scutellariae barbatae, fresh aloe, herba ecliptae and rhizoma zingiberis into water, decocting for 15-20 minutes, separating residues, cooling, sequentially adding camphor and antibiotics into filtrate, and stirring until the camphor and the antibiotics are dissolved to obtain the medicine.
7. The method for preparing the anti-novel coronavirus drug according to claim 6, wherein the temperature of the filtrate when camphor and an antibiotic are added in the step S2 is 75-80 ℃; the volume of the prepared drug is 1000-1500 ml.
8. Use of an anti-neocoronavirus drug comprising nebulizing the drug prepared in claim 6 into a sauna room using one of a humidifier or nebulizer.
9. The use of claim 8 for resisting novel coronavirus, wherein the temperature of the top of the sauna room is 65-70 ℃.
10. The use of the novel coronavirus resistant agent according to any one of claims 1 to 5, wherein the use of the novel coronavirus resistant agent is used for preparing a medicament for improving the human immunity of a patient infected with the novel coronavirus 2019.
CN202010338859.9A 2020-04-26 2020-04-26 Medicine for resisting novel coronavirus, preparation method and application thereof Pending CN111544540A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114159445A (en) * 2020-09-11 2022-03-11 中国科学院分子细胞科学卓越创新中心 Method for screening small molecule drugs for inhibiting novel coronavirus infection and application thereof
WO2023022198A1 (en) * 2021-08-19 2023-02-23 国立大学法人東北大学 Novel prophylactic or therapeutic agent for novel coronavirus infection-related disease
CN115844967A (en) * 2022-09-06 2023-03-28 贵州碘雅医疗器械有限公司 Compound iodine disinfectant and preparation method and application thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
醉美微江夏: ""药来了！同济医院两款自制药可用于新冠肺炎的防治"", 《HTTPS://WWW.SOHU.COM/A/375268503_687058》 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114159445A (en) * 2020-09-11 2022-03-11 中国科学院分子细胞科学卓越创新中心 Method for screening small molecule drugs for inhibiting novel coronavirus infection and application thereof
CN114159445B (en) * 2020-09-11 2024-03-19 中国科学院分子细胞科学卓越创新中心 Method for screening small molecule drugs for inhibiting novel coronavirus infection and application thereof
WO2023022198A1 (en) * 2021-08-19 2023-02-23 国立大学法人東北大学 Novel prophylactic or therapeutic agent for novel coronavirus infection-related disease
CN115844967A (en) * 2022-09-06 2023-03-28 贵州碘雅医疗器械有限公司 Compound iodine disinfectant and preparation method and application thereof
CN115844967B (en) * 2022-09-06 2024-08-02 贵州碘雅医疗器械有限公司 Composite iodine disinfectant and preparation method and application thereof

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Application publication date: 20200818