CN111526914A - 电子呼吸致动式直线型液滴输送装置及其使用方法 - Google Patents

电子呼吸致动式直线型液滴输送装置及其使用方法 Download PDF

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Publication number
CN111526914A
CN111526914A CN201880073105.6A CN201880073105A CN111526914A CN 111526914 A CN111526914 A CN 111526914A CN 201880073105 A CN201880073105 A CN 201880073105A CN 111526914 A CN111526914 A CN 111526914A
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delivery device
droplet
droplets
mouthpiece
droplet delivery
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CN201880073105.6A
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English (en)
Chinese (zh)
Inventor
J·H·赫布朗克
C·E·亨特
C·W·毛雷尔
李成杰
L·T·格米纳里奥
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Pneuma Respiratory Inc
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Pneuma Respiratory Inc
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Application filed by Pneuma Respiratory Inc filed Critical Pneuma Respiratory Inc
Priority to CN202410176111.1A priority Critical patent/CN118203735A/zh
Publication of CN111526914A publication Critical patent/CN111526914A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/14Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A61M16/18Vaporising devices for anaesthetic preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/005Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
    • AHUMAN NECESSITIES
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M11/06Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • A61M15/0025Mouthpieces therefor with caps
    • A61M15/0026Hinged caps
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008Electronic counters
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M11/001Particle size control
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    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
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    • A61M2016/0027Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/35Communication
    • A61M2205/3576Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A61M2205/3592Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using telemetric means, e.g. radio or optical transmission
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61M2205/50General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502User interfaces, e.g. screens or keyboards
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/587Lighting arrangements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/60General characteristics of the apparatus with identification means
    • A61M2205/6054Magnetic identification systems
    • AHUMAN NECESSITIES
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8206Internal energy supply devices battery-operated
    • AHUMAN NECESSITIES
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8237Charging means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/11Laminar flow
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201880073105.6A 2017-10-04 2018-10-04 电子呼吸致动式直线型液滴输送装置及其使用方法 Pending CN111526914A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202410176111.1A CN118203735A (zh) 2017-10-04 2018-10-04 电子呼吸致动式直线型液滴输送装置及其使用方法

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201762568057P 2017-10-04 2017-10-04
US62/568,057 2017-10-04
US201762575165P 2017-10-20 2017-10-20
US62/575,165 2017-10-20
US201862622022P 2018-01-25 2018-01-25
US62/622,022 2018-01-25
US201862732455P 2018-09-17 2018-09-17
US62/732,455 2018-09-17
PCT/US2018/054417 WO2019071008A1 (en) 2017-10-04 2018-10-04 ELECTRONIC DEVICE FOR DELIVERY OF LINEAR SHAPE ADMINISTRATION OPERATED BY BREATHING AND METHODS OF USE

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CN202410176111.1A Pending CN118203735A (zh) 2017-10-04 2018-10-04 电子呼吸致动式直线型液滴输送装置及其使用方法

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US (2) US11738158B2 (https=)
EP (1) EP3691728B1 (https=)
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CN111479604A (zh) * 2017-11-08 2020-07-31 精呼吸股份有限公司 具有小体积安瓿的电动呼吸致动直列液滴输送装置及使用方法
CN112996605A (zh) * 2018-10-01 2021-06-18 精呼吸股份有限公司 低表面张力组合物经由电子呼吸致动式液滴递送装置向肺系统的递送

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EP4624054A3 (en) 2016-05-03 2025-11-19 Pneuma Respiratory, Inc. Methods for generating and delivering droplets to the pulmonary system using a droplet delivery device
WO2017192774A1 (en) 2016-05-03 2017-11-09 Pneuma Respiratory, Inc. Methods for the systemic delivery of therapeutic agents to the pulmonary system using a droplet delivery device
WO2017192782A1 (en) 2016-05-03 2017-11-09 Pneuma Respiratory, Inc. Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment
WO2017192773A1 (en) 2016-05-03 2017-11-09 Pneuma Respiratory, Inc. Methods for treatment of pulmonary lung diseases with improved therapeutic efficacy and improved dose efficiency
WO2018213834A1 (en) 2017-05-19 2018-11-22 Pneuma Respiratory, Inc. Dry powder delivery device and methods of use
EP4344719B1 (en) 2017-10-17 2025-12-31 Pneuma Respiratory, Inc. NASAL MEDICATION ADMINISTRATION DEVICE
CA3087769A1 (en) * 2018-01-08 2019-07-11 Pneuma Respiratory, Inc. Treatment of pulmonary cancers using an electronic breath actuated droplet delivery device
US11517685B2 (en) 2019-01-18 2022-12-06 Qnovia, Inc. Electronic device for producing an aerosol for inhalation by a person
US12501929B2 (en) 2018-08-22 2025-12-23 Qnovia, Inc. Electronic device for producing an aerosol for inhalation by a person
CA3110469A1 (en) 2018-08-22 2020-02-27 Respira Technologies, Inc. Electronic device for producing an aerosol for inhalation by a person
US11690963B2 (en) 2018-08-22 2023-07-04 Qnovia, Inc. Electronic device for producing an aerosol for inhalation by a person
US20210077753A1 (en) * 2019-04-01 2021-03-18 Bn Intellectual Properties, Inc. Nebulizer delivery systems and methods
US11406786B2 (en) * 2019-04-22 2022-08-09 Sunovion Pharmaceuticals Inc. Nebulizer monitoring device, system and method
KR20220002979A (ko) * 2019-05-03 2022-01-07 제이티 인터내셔널 소시에떼 아노님 검출기가 있는 이동식 마개를 갖는 에어로졸 발생 장치
JP7434361B2 (ja) * 2019-05-07 2024-02-20 キンデーバ ドラッグ デリバリー リミティド パートナーシップ 警告システム、吸入器及び警告生成方法
CA3144418A1 (en) * 2019-06-27 2020-12-30 Pneuma Respiratory, Inc. Delivery of small droplets to the respiratory system via electronic breath actuated droplet delivery device
US11889861B2 (en) 2019-09-23 2024-02-06 Rai Strategic Holdings, Inc. Arrangement of atomization assemblies for aerosol delivery device
EP3967347B1 (de) * 2020-09-09 2023-05-31 Pulmotree Medical GmbH Vernebler
CN116322848B (zh) * 2020-10-16 2026-02-10 维克多瑞传送设备有限公司 用于检测振动膜喷雾器中液体存在的方法
US12471625B2 (en) 2020-11-01 2025-11-18 Qnovia, Inc. Electronic devices and liquids for aerosolizing and inhaling therewith
US11969545B2 (en) 2020-12-01 2024-04-30 Rai Strategic Holdings, Inc. Liquid feed systems for an aerosol delivery device
US11793945B2 (en) 2021-06-22 2023-10-24 Pneuma Respiratory, Inc. Droplet delivery device with push ejection
JP2024533453A (ja) * 2021-09-12 2024-09-12 ニコノックス エルエルシー 送達デバイスおよび組成物
US12484618B2 (en) 2022-04-22 2025-12-02 Qnovia, Inc. Electronic devices for aerosolizing and inhaling liquid having diaphragm and a pressure sensor
CN119768202A (zh) 2022-07-18 2025-04-04 精呼吸股份有限公司 小步长高分辨率气溶胶生成系统及方法
US12550948B2 (en) 2022-08-19 2026-02-17 Rai Strategic Holdings, Inc. Pressurized aerosol delivery device
WO2025129612A1 (en) * 2023-12-22 2025-06-26 Imperial Tobacco Limited Aerosol generating apparatus
CN120287550B (zh) * 2025-06-13 2025-08-19 西安高达新材料科技有限公司 一种聚酯型抗静电粉末涂料的制备方法

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