CN111448321A - Sod1双表达载体及其用途 - Google Patents

Sod1双表达载体及其用途 Download PDF

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Publication number
CN111448321A
CN111448321A CN201880061583.5A CN201880061583A CN111448321A CN 111448321 A CN111448321 A CN 111448321A CN 201880061583 A CN201880061583 A CN 201880061583A CN 111448321 A CN111448321 A CN 111448321A
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nucleic acid
promoter
sod1
isolated nucleic
sequence
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CN201880061583.5A
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Chinese (zh)
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C·米勒
R·H·小布朗
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University of Massachusetts Amherst
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University of Massachusetts Amherst
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CN201880061583.5A 2017-09-22 2018-09-21 Sod1双表达载体及其用途 Pending CN111448321A (zh)

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US201762561932P 2017-09-22 2017-09-22
US62/561,932 2017-09-22
PCT/US2018/052173 WO2019060686A1 (en) 2017-09-22 2018-09-21 NEW DUAL EXPRESSION VECTORS OF SOD1 AND USES THEREOF

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EP (1) EP3684937A4 (enExample)
JP (3) JP7397488B2 (enExample)
CN (2) CN111448321A (enExample)
AU (2) AU2018338188B2 (enExample)
CA (1) CA3075643A1 (enExample)
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CN111448321A (zh) 2017-09-22 2020-07-24 马萨诸塞大学 Sod1双表达载体及其用途
WO2022060857A1 (en) * 2020-09-16 2022-03-24 Biogen Ma Inc. Compositions and methods for treating amyotrophic lateral sclerosis (als) with aav-mir-sod1
EP4291654A2 (en) 2021-02-12 2023-12-20 Alnylam Pharmaceuticals, Inc. Superoxide dismutase 1 (sod1) irna compositions and methods of use thereof for treating or preventing superoxide dismutase 1- (sod1-) associated neurodegenerative diseases
WO2025072224A1 (en) * 2023-09-25 2025-04-03 California Institute Of Technology Mirna circuits for controlled gene expression

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