CN111388520A - Fermentation method of Jianqu - Google Patents
Fermentation method of Jianqu Download PDFInfo
- Publication number
- CN111388520A CN111388520A CN201911127426.2A CN201911127426A CN111388520A CN 111388520 A CN111388520 A CN 111388520A CN 201911127426 A CN201911127426 A CN 201911127426A CN 111388520 A CN111388520 A CN 111388520A
- Authority
- CN
- China
- Prior art keywords
- parts
- flour
- fermentation method
- bran
- herba
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/289—Vladimiria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/532—Agastache, e.g. giant hyssop
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/89—Cyperaceae (Sedge family)
- A61K36/8905—Cyperus (flatsedge)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8998—Hordeum (barley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Nutrition Science (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the field of traditional Chinese medicine decoction pieces, in particular to a fermentation method of Jian Qu. The invention overcomes the defect that the effective components in the raw materials for preparing the koji in the prior art are not released to cause poor drug effect of the most prepared koji, and has the advantages that the effective components of the drug can be fully exerted and can not be damaged, thereby having good drug effect of the koji.
Description
Technical Field
The invention relates to the field of traditional Chinese medicine decoction pieces, in particular to a fermentation method of Jianqu.
Background
Jian Qu is recorded in the book number of Z17-142 in the pharmaceutical Standard "Chinese medicine Cheng Fang Zhi (seventeenth volume) of the Ministry of health of the people's republic of China, has slightly bitter taste and fragrant smell, has the efficacy of relieving exterior syndrome and regulating the middle warmer, and is mainly used for headache due to cold and heat, food stagnation and vomiting and fullness. The preparation method comprises pulverizing the above materials into fine powder, mixing with testa Tritici, sieving, making flour into paste, mixing with the above powder, making into square blocks, fermenting until the blocks become white mould and have wine fragrance, and drying. Meanwhile, the characteristics of the koji-making prepared in the standard 'quality standard of the koji-making' (standard code number WS-B-3238-98) issued by the Ministry of health of China are as follows: the product is a yellow brown rectangular block, has rough outer surface, yellow brown color, white mold, loose cross section, and yellow brown color; fragrant smell and slightly bitter taste.
Disclosure of Invention
The invention provides a fermentation method of Jian qu, which can effectively improve the drug effect of the Jian qu and aims to overcome the defect that the drug effect of the Jian qu prepared in the middle is poor due to the fact that the active ingredients in the raw materials for preparing the Jian qu are not released in the prior art.
In order to achieve the purpose, the invention is realized by the following technical scheme:
a fermentation method of Jianqu comprises 106 parts of flour, 212 parts of bran, 40 parts of phaseolus calcaratus, 40 parts of bitter almond, 66 parts of sweet wormwood, 66 parts of polygonum hydropiper, 66 parts of xanthium sibiricum, 60 parts of pogostemon cablin, 90 parts of malt, 90 parts of rice sprout, 90 parts of fried hawthorn, 60 parts of dried orange peel, 60 parts of perilla leaf, 60 parts of rhizoma cyperi, 60 parts of rhizoma atractylodis, 30 parts of bran-fried fructus aurantii, 30 parts of betel nut, 30 parts of mint, 30 parts of mangnolia officinalis, 30 parts of radix aucklandiae, 30 parts of radix angelicae, 15 parts of cinnamon and 15 parts of liquorice according to mass fraction, and comprises the following steps:
(1) crushing and uniformly mixing: pulverizing semen Phaseoli, semen Armeniacae amarum, herba Artemisiae Annuae, herba Polygoni Hydropiperis, herba Xanthii, herba Agastaches, fructus Hordei Germinatus, fructus crataegi preparata, pericarpium Citri Tangerinae, folium Perillae, rhizoma Cyperi, rhizoma Atractylodis, fructus Aurantii parched with bran, Arecae semen, herba Menthae, cortex Magnolia officinalis, radix aucklandiae, radix Angelicae Dahuricae, cortex Cinnamomi, and Glycyrrhrizae radix, sieving, and mixing to obtain mixed powder;
(2) uniformly stirring and cutting: sieving the mixed powder, bran and flour, mixing, adding Aspergillus oryzae spore powder, mixing with water, and cutting into rectangular blocks;
(3) fermentation: spreading the cut Massa Medicata Fermentata on stainless steel plate, fermenting, and taking out when there is white mold and wine aroma;
(4) and (3) drying: and (5) uniformly spreading the Jian Qu until the Jian Qu is dried.
Preferably, the particle size of the mixed powder in the step (1) is 80-150 meshes.
Preferably, the mass ratio of the flour to the water in the step (4) is 106: (900-1000).
Preferably, the mass ratio of the flour to the aspergillus oryzae spore powder in the step (2) is 100: (0.5-2.5).
Preferably, the fermentation temperature in the step (3) is 26-32 ℃.
Preferably, the fermentation relative humidity in the step (3) is 65-85%.
Preferably, in the step (6), the drying temperature is 50-70 ℃, and the drying time is 8-24 h.
Therefore, the invention has the following beneficial effects:
(1) the effective components of the medicine can be fully exerted and cannot be damaged;
(2) the medicinal effect of the medicinal starter is good.
Detailed Description
The invention is further described with reference to specific examples. The following description of the embodiments is provided to enable any person skilled in the art to make and use the invention. It will be readily apparent to those skilled in the art that various modifications to these embodiments may be made, and the generic principles described herein may be applied to other embodiments without the use of the inventive faculty. Therefore, the present invention is not limited to the following embodiments, and those skilled in the art should make improvements and modifications within the scope of the present invention based on the disclosure of the present invention.
Example 1
A fermentation method of Jianqu comprises 106 parts of flour, 212 parts of bran, 40 parts of phaseolus calcaratus, 40 parts of bitter almond, 66 parts of sweet wormwood, 66 parts of polygonum hydropiper, 66 parts of xanthium sibiricum, 60 parts of pogostemon cablin, 90 parts of malt, 90 parts of rice sprout, 90 parts of fried hawthorn, 60 parts of dried orange peel, 60 parts of perilla leaf, 60 parts of rhizoma cyperi, 60 parts of rhizoma atractylodis, 30 parts of bran-fried fructus aurantii, 30 parts of betel nut, 30 parts of mint, 30 parts of mangnolia officinalis, 30 parts of radix aucklandiae, 30 parts of radix angelicae, 15 parts of cinnamon and 15 parts of liquorice according to mass fraction, and comprises the following steps:
(1) crushing and uniformly mixing: pulverizing semen Phaseoli, semen Armeniacae amarum, herba Artemisiae Annuae, herba Polygoni Hydropiperis, herba Xanthii, herba Agastaches, fructus Hordei Germinatus, parched fructus crataegi, pericarpium Citri Tangerinae, folium Perillae, rhizoma Cyperi, rhizoma Atractylodis, bran-parched fructus Aurantii, Arecae semen, herba Menthae, cortex Magnolia officinalis, radix aucklandiae, radix Angelicae Dahuricae, cortex Cinnamomi, and Glycyrrhrizae radix into 80 mesh, sieving, and mixing to obtain mixed powder;
(2) uniformly stirring and cutting: sieving and uniformly mixing the mixed powder, bran and flour, adding aspergillus oryzae spore powder, wherein the mass ratio of the flour to the aspergillus oryzae spore powder is 100: 0.5, uniformly mixing the flour with water, placing the mixture on a medicine slicing machine, and slicing the mixture into rectangular blocks, wherein the mass ratio of the flour to the water is 106: 900;
(3) fermentation: spreading the cut Massa Medicata Fermentata on stainless steel plate, fermenting at 26 deg.C and humidity of 65%, and taking out when there is white mold and wine aroma;
(4) and (3) drying: the Jian Qu is evenly spread out at 50 ℃ and dried for 8 h.
Example 2
A fermentation method of Jianqu comprises 106 parts of flour, 212 parts of bran, 40 parts of phaseolus calcaratus, 40 parts of bitter almond, 66 parts of sweet wormwood, 66 parts of polygonum hydropiper, 66 parts of xanthium sibiricum, 60 parts of pogostemon cablin, 90 parts of malt, 90 parts of rice sprout, 90 parts of fried hawthorn, 60 parts of dried orange peel, 60 parts of perilla leaf, 60 parts of rhizoma cyperi, 60 parts of rhizoma atractylodis, 30 parts of bran-fried fructus aurantii, 30 parts of betel nut, 30 parts of mint, 30 parts of mangnolia officinalis, 30 parts of radix aucklandiae, 30 parts of radix angelicae, 15 parts of cinnamon and 15 parts of liquorice according to mass fraction, and comprises the following steps:
(1) crushing and uniformly mixing: pulverizing semen Phaseoli, semen Armeniacae amarum, herba Artemisiae Annuae, herba Polygoni Hydropiperis, herba Xanthii, herba Agastaches, fructus Hordei Germinatus, parched fructus crataegi, pericarpium Citri Tangerinae, folium Perillae, rhizoma Cyperi, rhizoma Atractylodis, bran-parched fructus Aurantii, Arecae semen, herba Menthae, cortex Magnolia officinalis, radix aucklandiae, radix Angelicae Dahuricae, cortex Cinnamomi, and Glycyrrhrizae radix into 150 mesh, sieving, and mixing to obtain mixed powder;
(2) uniformly stirring and cutting: sieving and uniformly mixing the mixed powder, bran and flour, adding aspergillus oryzae spore powder, wherein the mass ratio of the flour to the aspergillus oryzae spore powder is 100: 2.5, uniformly mixing the flour with water, placing the mixture on a medicine slicing machine, and slicing the mixture into rectangular blocks, wherein the mass ratio of the flour to the water is 106: 1000, parts by weight;
(3) fermentation: spreading the cut Massa Medicata Fermentata on stainless steel plate, fermenting at 32 deg.C and 85% humidity, and taking out when there is white mold and wine aroma;
(4) and (3) drying: the Jian Qu is evenly spread out at 70 ℃ and dried for 24 h.
Example 3
A fermentation method of Jianqu comprises 106 parts of flour, 212 parts of bran, 40 parts of phaseolus calcaratus, 40 parts of bitter almond, 66 parts of sweet wormwood, 66 parts of polygonum hydropiper, 66 parts of xanthium sibiricum, 60 parts of pogostemon cablin, 90 parts of malt, 90 parts of rice sprout, 90 parts of fried hawthorn, 60 parts of dried orange peel, 60 parts of perilla leaf, 60 parts of rhizoma cyperi, 60 parts of rhizoma atractylodis, 30 parts of bran-fried fructus aurantii, 30 parts of betel nut, 30 parts of mint, 30 parts of mangnolia officinalis, 30 parts of radix aucklandiae, 30 parts of radix angelicae, 15 parts of cinnamon and 15 parts of liquorice according to mass fraction, and comprises the following steps:
(1) crushing and uniformly mixing: pulverizing semen Phaseoli, semen Armeniacae amarum, herba Artemisiae Annuae, herba Polygoni Hydropiperis, herba Xanthii, herba Agastaches, fructus Hordei Germinatus, parched fructus crataegi, pericarpium Citri Tangerinae, folium Perillae, rhizoma Cyperi, rhizoma Atractylodis, bran-parched fructus Aurantii, Arecae semen, herba Menthae, cortex Magnolia officinalis, radix aucklandiae, radix Angelicae Dahuricae, cortex Cinnamomi, and Glycyrrhrizae radix into 100 mesh, sieving, and mixing to obtain mixed powder;
(2) uniformly stirring and cutting: sieving and uniformly mixing the mixed powder, bran and flour, adding aspergillus oryzae spore powder, wherein the mass ratio of the flour to the aspergillus oryzae spore powder is 100: 1, uniformly mixing the flour with water, placing the mixture on a medicine slicing machine, and slicing the mixture into rectangular blocks, wherein the mass ratio of the flour to the water is 106: 950;
(3) fermentation: spreading the cut Massa Medicata Fermentata on stainless steel plate, fermenting at 29 deg.C and 75% humidity, and taking out when there is white mold and wine aroma;
(4) and (3) drying: the Jian Qu is evenly spread out at 55 ℃ and dried for 10 h.
Example 4
A fermentation method of Jianqu comprises 106 parts of flour, 212 parts of bran, 40 parts of phaseolus calcaratus, 40 parts of bitter almond, 66 parts of sweet wormwood, 66 parts of polygonum hydropiper, 66 parts of xanthium sibiricum, 60 parts of pogostemon cablin, 90 parts of malt, 90 parts of rice sprout, 90 parts of fried hawthorn, 60 parts of dried orange peel, 60 parts of perilla leaf, 60 parts of rhizoma cyperi, 60 parts of rhizoma atractylodis, 30 parts of bran-fried fructus aurantii, 30 parts of betel nut, 30 parts of mint, 30 parts of mangnolia officinalis, 30 parts of radix aucklandiae, 30 parts of radix angelicae, 15 parts of cinnamon and 15 parts of liquorice according to mass fraction, and comprises the following steps:
(1) crushing and uniformly mixing: pulverizing semen Phaseoli, semen Armeniacae amarum, herba Artemisiae Annuae, herba Polygoni Hydropiperis, herba Xanthii, herba Agastaches, fructus Hordei Germinatus, fructus crataegi preparata, pericarpium Citri Tangerinae, folium Perillae, rhizoma Cyperi, rhizoma Atractylodis, fructus Aurantii parched with bran, Arecae semen, herba Menthae, cortex Magnolia officinalis, radix aucklandiae, radix Angelicae Dahuricae, cortex Cinnamomi, and Glycyrrhrizae radix into 120 mesh, sieving, and mixing to obtain mixed powder;
(2) uniformly stirring and cutting: sieving and uniformly mixing the mixed powder, bran and flour, adding aspergillus oryzae spore powder, wherein the mass ratio of the flour to the aspergillus oryzae spore powder is 100: 1.5, uniformly mixing the flour with water, placing the mixture on a medicine slicing machine, and slicing the mixture into rectangular blocks, wherein the mass ratio of the flour to the water is 106: 980;
(3) fermentation: spreading the cut Massa Medicata Fermentata on stainless steel plate, fermenting at 30 deg.C and humidity of 80%, and taking out when there is white mold and wine aroma;
(4) and (3) drying: the Jian Qu is evenly spread out at 65 ℃ and dried for 15 h.
Example 5
A fermentation method of Jianqu comprises 106 parts of flour, 212 parts of bran, 40 parts of phaseolus calcaratus, 40 parts of bitter almond, 66 parts of sweet wormwood, 66 parts of polygonum hydropiper, 66 parts of xanthium sibiricum, 60 parts of pogostemon cablin, 90 parts of malt, 90 parts of rice sprout, 90 parts of fried hawthorn, 60 parts of dried orange peel, 60 parts of perilla leaf, 60 parts of rhizoma cyperi, 60 parts of rhizoma atractylodis, 30 parts of bran-fried fructus aurantii, 30 parts of betel nut, 30 parts of mint, 30 parts of mangnolia officinalis, 30 parts of radix aucklandiae, 30 parts of radix angelicae, 15 parts of cinnamon and 15 parts of liquorice according to mass fraction, and comprises the following steps:
(1) crushing and uniformly mixing: pulverizing semen Phaseoli, semen Armeniacae amarum, herba Artemisiae Annuae, herba Polygoni Hydropiperis, herba Xanthii, herba Agastaches, fructus Hordei Germinatus, fructus crataegi preparata, pericarpium Citri Tangerinae, folium Perillae, rhizoma Cyperi, rhizoma Atractylodis, fructus Aurantii parched with bran, Arecae semen, herba Menthae, cortex Magnolia officinalis, radix aucklandiae, radix Angelicae Dahuricae, cortex Cinnamomi, and Glycyrrhrizae radix into 140 mesh, sieving, and mixing to obtain mixed powder;
(2) uniformly stirring and cutting: sieving and uniformly mixing the mixed powder, bran and flour, adding aspergillus oryzae spore powder, wherein the mass ratio of the flour to the aspergillus oryzae spore powder is 100: 2, uniformly mixing the flour with water, placing the mixture on a medicine slicing machine, and slicing the mixture into rectangular blocks, wherein the mass ratio of the flour to the water is 106: 980;
(3) fermentation: spreading the cut Massa Medicata Fermentata on stainless steel plate, fermenting at 30 deg.C and humidity of 70%, and taking out when there is white mold and wine aroma;
(4) and (3) drying: the Jian Qu is evenly spread out at 70 ℃ and dried for 18 h.
The aspergillus built obtained in the embodiments 1-5 is used for measuring aflatoxin B1 according to the guide principle of mycotoxin measurement in four parts 9305 traditional Chinese medicine in pharmacopoeia of the people's republic of China 2015, and no aflatoxin B1 is detected in the finished product of the aspergillus built.
Claims (7)
1. A fermentation method of Jianqu comprises 106 parts of flour, 212 parts of bran, 40 parts of phaseolus calcaratus, 40 parts of bitter almond, 66 parts of sweet wormwood, 66 parts of polygonum hydropiper, 66 parts of xanthium sibiricum, 60 parts of cablin potchouli herb, 90 parts of malt, 90 parts of rice sprout, 90 parts of fried hawthorn, 60 parts of dried orange peel, 60 parts of perilla leaf, 60 parts of rhizoma cyperi, 60 parts of rhizoma atractylodis, 30 parts of bran-fried fructus aurantii, 30 parts of betel nut, 30 parts of mint, 30 parts of mangnolia officinalis, 30 parts of radix aucklandiae, 30 parts of radix angelicae, 15 parts of cinnamon and 15 parts of liquorice according to mass fraction, and is characterized by comprising the following steps:
(1) crushing and uniformly mixing: pulverizing semen Phaseoli, semen Armeniacae amarum, herba Artemisiae Annuae, herba Polygoni Hydropiperis, herba Xanthii, herba Agastaches, fructus Hordei Germinatus, fructus crataegi preparata, pericarpium Citri Tangerinae, folium Perillae, rhizoma Cyperi, rhizoma Atractylodis, fructus Aurantii parched with bran, Arecae semen, herba Menthae, cortex Magnolia officinalis, radix aucklandiae, radix Angelicae Dahuricae, cortex Cinnamomi, and Glycyrrhrizae radix, sieving, and mixing to obtain mixed powder;
(2) uniformly stirring and cutting: sieving the mixed powder, bran and flour, mixing, adding Aspergillus oryzae spore powder, mixing with water, and cutting into rectangular blocks;
(3) fermentation: spreading the cut Massa Medicata Fermentata on stainless steel plate, fermenting, and taking out when there is white mold and wine aroma;
(4) and (3) drying: and (5) uniformly spreading the Jian Qu until the Jian Qu is dried.
2. The fermentation method of koji making according to claim 1, wherein the particle size of the powder mixture in step (1) is in the range of 80 to 150 mesh.
3. The fermentation method of koji making according to claim 1, wherein the mass ratio of flour to water in step (2) is 106: (900-1000).
4. The fermentation method of koji-making according to claim 1 or 3, wherein the mass ratio of the flour to the Aspergillus oryzae spore powder in the step (2) is 100: (0.5-2.5).
5. The fermentation method of koji making according to claim 1, wherein the fermentation temperature in the step (3) is 26-32 ℃.
6. The fermentation method of koji making according to claim 1, wherein the fermentation relative humidity in step (3) is 65-85%.
7. The fermentation method of koji making according to claim 1, wherein the drying temperature in step (4) is 50 to 70 ℃ and the drying time is 8 to 24 hours.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911127426.2A CN111388520A (en) | 2019-11-18 | 2019-11-18 | Fermentation method of Jianqu |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911127426.2A CN111388520A (en) | 2019-11-18 | 2019-11-18 | Fermentation method of Jianqu |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111388520A true CN111388520A (en) | 2020-07-10 |
Family
ID=71415035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911127426.2A Pending CN111388520A (en) | 2019-11-18 | 2019-11-18 | Fermentation method of Jianqu |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111388520A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113713061A (en) * | 2021-08-27 | 2021-11-30 | 四川百胜药业有限公司 | Jian qu and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102058759A (en) * | 2010-12-31 | 2011-05-18 | 广东太安堂药业股份有限公司 | Medicinal tea prepared from Chinese medicinal materials by microbial fermentation |
| CN104547767A (en) * | 2014-12-26 | 2015-04-29 | 四川百胜药业有限公司 | Processing method of medicinal fermented mass particles |
| CN105267249A (en) * | 2015-06-19 | 2016-01-27 | 王秋红 | Method for preparing shenqu by purebred fermentation |
| CN106039139A (en) * | 2016-07-18 | 2016-10-26 | 泸州正泰生物工程有限公司 | Traditional Chinese medicine fermenting agent and preparation method thereof |
-
2019
- 2019-11-18 CN CN201911127426.2A patent/CN111388520A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102058759A (en) * | 2010-12-31 | 2011-05-18 | 广东太安堂药业股份有限公司 | Medicinal tea prepared from Chinese medicinal materials by microbial fermentation |
| CN104547767A (en) * | 2014-12-26 | 2015-04-29 | 四川百胜药业有限公司 | Processing method of medicinal fermented mass particles |
| CN105267249A (en) * | 2015-06-19 | 2016-01-27 | 王秋红 | Method for preparing shenqu by purebred fermentation |
| CN106039139A (en) * | 2016-07-18 | 2016-10-26 | 泸州正泰生物工程有限公司 | Traditional Chinese medicine fermenting agent and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| 刘亚明，主编: "《发酵技术在中医药中的应用》", 31 March 2010, 中国中医药出版社 * |
| 戴龙瑞，等: "浅论六曲和建曲的组方、制作及改良途径", 《上海中医药杂志》 * |
| 王延年，等: "中药发酵研究进展", 《世界科学技术(中医药现代化)》 * |
| 贾晓归: "疏肝健脾汤治疗肠易激综合征36例", 《中国医药导报》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113713061A (en) * | 2021-08-27 | 2021-11-30 | 四川百胜药业有限公司 | Jian qu and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103918830A (en) | Warming tea beverage | |
| CN105831594A (en) | Delicious tongue-numbing spicy gluten strip and preparation method thereof | |
| CN105851870A (en) | Hot and spicy gluten strip and preparation method thereof | |
| CN109007828A (en) | A kind of colla corii asini cake and preparation method thereof with rich in nutrition effect | |
| CN111418750A (en) | Polygonatum odoratum solid beverage and preparation method thereof | |
| CN107115460B (en) | Polygonatum sibiricum compound electuary with blood fat reducing effect and preparation method thereof | |
| CN104547767B (en) | A kind of concocting method for building bent particle | |
| CN111388520A (en) | Fermentation method of Jianqu | |
| CN111406816A (en) | Series tea substitute with five colors of tea soup and preparation method thereof | |
| CN105876019A (en) | Method for making lavender tea | |
| CN103272207B (en) | Traditional Chinese medicine for treating nerve headaches and preparation method of traditional Chinese medicine | |
| CN105617148B (en) | One kind building bent preparation method | |
| CN101317983A (en) | Method for preparing capsule for nourishing Yin and suppressing Yang, discharging fire and pacifying the mind | |
| CN104095123A (en) | Cool and refreshing type health-care tea with hippophae rhamnosides leaves and preparation method thereof | |
| CN103463208A (en) | Granules for preventing and treating piglet diarrhea and preparation method for granules | |
| CN103446469B (en) | Preparation method of pinellia rhizome fermented mass | |
| CN113797294A (en) | Medicine composition for treating atrophic gastritis and preparation method thereof | |
| CN106474330A (en) | A kind of tranquillizing and allaying excitement alternative tea made as composition using food plant | |
| CN116077613A (en) | Traditional Chinese medicine preparation for treating spleen and stomach diseases and preparation method and application thereof | |
| CN107582920A (en) | One kind builds bent and its concocting method | |
| CN105056170A (en) | Application of traditional Chinese medicine composition in preparing drug for treating acute gastritis | |
| CN104757585A (en) | Folium eriobotryae sausage and making method thereof | |
| CN109316589A (en) | A kind of drug and preparation method thereof for treating stomach trouble | |
| CN101317949A (en) | Method for preparing capsule for nourishing blood, regulating menstruation and nourishing blood and liver | |
| CN106620210A (en) | Preparation method of mind-tranquilizing substitute tea prepared by taking food plants as components |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200710 |