CN103272207B - Traditional Chinese medicine for treating nerve headaches and preparation method of traditional Chinese medicine - Google Patents
Traditional Chinese medicine for treating nerve headaches and preparation method of traditional Chinese medicine Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine for treating nerve headaches. The traditional Chinese medicine is prepared by primary medicines and auxiliary medicines. Each dosage of medicinal materials is as follows: the primary materials: 4 g of asarum, 30 g of angelica sinensis, 8 g of safflower carthamus, 12 g of Chinese parsnip roots, 8 g of notopterygium roots, 10 g of prepared rehmannia roots, 30 g of gypsum, 15 g of tuber fleeceflower stems, 4 centipedes, 10 g of scorpions and 20 g of nutgrass galingale rhizome; and the auxiliary medicines: 30 g of Ligusticum wallichii, 7 g of chastetree fruits, 6 g of white paeony roots, 12 g of chrysanthemum, 10 g of mint, 20 g of concha haliotidis, 8 g of fructus evodiae and 10 g of fresh ginger. A preparation method comprises the steps as follows: the centipedes and the scorpions are crushed for standby use; then the medicinal materials are cleaned, dried, crushed and sterilized respectively, and are mixed according to the formula proportion; water is added, the materials are steeped and heated for three times through steam, and effective ingredients are extracted; an extract is prepared through filtration; then the extract is dried, crushed and ground into powder; powder of the centipedes and the scorpions is added and uniformly mixed; and finally the powder is crushed into tablets or filled into capsules, so that the traditional Chinese medicine for treating the nerve headaches is obtained. The traditional Chinese medicine is remarkable in treatment effect and applicable to treatment on patients suffering from the nerve headaches caused by various pathogeneses.
Description
Technical field
The present invention is relevant with medicinal preparation, in particular to the medicine for the treatment of nervous headache, also relates to the preparation method of this Chinese medicine.
Background technology
Nervous headache mainly refers to tension headache, functional headache and angioneurotic headache, how to be caused by psychentonia, anger, the vexed pain of head, constriction, sense of heaviness that cardinal symptom is persistence, and have " lock ring " that have felt.Most patients is amphicrania, mostly is two temporo sides, rear pillow part and head or full head.Headache character is dull pain, distending pain, constriction, feeling of numbness and the sense of band sample lock ring.
Increase very fast with the Chinese patent application part of Chinese crude drug treatment nervous headache disease in recent years, for example No. 200810014884.0 " a kind of Chinese medicine preparation for the treatment of nervous headache ", number 200910019186.4 " a kind of Chinese medicine composition for the treatment of nervous headache ", number 201010258392.3 " a kind of decoction medicine for the treatment of nervous headache ", number 201010136566.9 " a kind of Chinese medicine for the treatment of nervous headache ", number 201110003320.9 " a kind of Chinese medicine preparation for the treatment of nervous headache and preparation method thereof ", number 201110316165.6 " a kind of Chinese medicine for the treatment of nervous headache ", number 201210097956.9 " Chinese medicine preparation for the treatment of nervous headache ", No. 201210565521.2 " treatment nervous headache Chinese medicine formulas " and No. 201310044454.4 " a kind of medicines for the treatment of nervous headache and preparation method thereof " etc.These patent applications all disclose some Drug therapy nervous headache diseases of utilizing Chinese crude drug to prepare, but its curative effect there is no report.Therefore people are still at exploitation renewal, more effective medicine.
Summary of the invention
Object of the present invention is just to provide a kind of Chinese medicine for the treatment of nervous headache disease, to increase the types of drugs for the treatment of nervous headache disease, enables the health service into people.
Another object of the present invention is to provide the preparation method of this Chinese medicine.
The Chinese medicine for the treatment of nervous headache disease of the present invention is formulated by 11 taste principal agents and 8 taste accessory drugss, and the principal agent of every potion Chinese medicine and the medical material of accessory drugs are:
Principal agent: Herba Asari 4g, Radix Angelicae Sinensis 30g, Flos Carthami 8g, Radix Saposhnikoviae 12g, Rhizoma Et Radix Notopterygii 8g, Radix Rehmanniae Preparata 10g, Gypsum Fibrosum 30g, Caulis Polygoni Multiflori 15g, 4 of Scolopendras, Scorpio 10g, Rhizoma Cyperi 20g;
Accessory drugs: Rhizoma Chuanxiong 30g, Fructus Viticis 7g, Radix Paeoniae Alba 6g, Flos Chrysanthemi 12g, Herba Menthae 10g, Concha Haliotidis 20g, Fructus Evodiae 8g, Rhizoma Zingiberis Recens 10g.
In above-mentioned principal agent medical material:
herba Asarifor Fructus Aristolochiae plant Herba Asari (
asarum sieboldii) whole herb with root, acrid in the mouth, warm in nature, can dispel the wind, cold expelling, Hang Shui, have one's ideas straightened out (see the new medical college in Jiangsu compile " Chinese medicine voluminous dictionary " 1477 pages);
radix Angelicae Sinensis,for umbelliferae angelica (
angelica sinensis) root, sweet in the mouth is pungent, warm in nature, the effect that has benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation can be controlled menoxenia, headache due to deficiency of blood, dizzy, the numbness of withering (seeing " Chinese medicine voluminous dictionary " 876 pages);
flos Carthamifor irides Stigma Croci (
crocus sativus) top and the stigma of style, sweet in the mouth, property is flat, can blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens (seeing " Chinese medicine voluminous dictionary " 2671 pages);
radix Saposhnikoviae, for umbelliferae Saposhnikovia divaricata (
saposhnikovia divaricata) root, acrid-sweet flavor, warm in nature, can deliver, dispel the wind, victory is wet, pain relieving, controls affection of exogenous wind-cold, headache and dizziness, anemofrigid-damp arthralgia, joint are ached, tetanus (seeing " Chinese medicine voluminous dictionary " 985 pages);
rhizoma Et Radix Notopterygii, for samphire Rhizoma Et Radix Notopterygii (
notopterygium incisum) rhizome, acrid in the mouth hardship, warm in nature, can fall apart exterior cold, wind-damp dispelling, sharp joint, the wind and cold that cures cold, anemofrigid-damp arthralgia, edema due to wind pathogen edema (seeing " Chinese medicine voluminous dictionary " 172 pages);
radix Rehmanniae Preparata, for scrophulariaceae rehmannia glutinosa plant (
rehmannia glutinosa) rhizome, sweet in the mouth, slightly warm in nature, the effect of have YIN nourishing, enriching blood, can control deficiency of YIN insufficiency of blood, the waist knee joint disease (seeing " Chinese medicine voluminous dictionary " 2626 pages) such as weak of withering;
gypsum Fibrosum(Gypsum Fibrosum), for Sulfates mineral gypsum (
cypsum) Ore, acrid-sweet flavor, cold in nature, expelling pathogenic factors from muscles for clearing heat, relieving restlessness quench the thirst (seeing " Chinese medicine voluminous dictionary " 592 pages);
caulis Polygoni Multiflorifor polygonum multiflorum thunb (
polygonum multiflorum) rattan or leaf bine stem, sweet and slightly bitter taste, property is flat, can tranquilizing by nourishing the heart, dredging collateral dispel the wind (seeing " Chinese medicine voluminous dictionary " 1443 pages);
scolopendra,for Scolopendra section animal Scolopendpa Subspinipes Mutilans L. KOCH (
scolopendra subspinipes) dry Scorpio, acrid in the mouth, warm in nature, poisonous, can dispel the wind, fixed warp, counteracting toxic substances, eliminating stagnation (seeing " Chinese medicine voluminous dictionary " 2473 pages);
scorpio, i.e. Scorpio, for Buthidae animal Scorpio (
buthus martensi) dry Scorpio, salty in the mouth is pungent, property is flat, poisonous, can dispel the wind, pain relieving, (seeing " Chinese medicine voluminous dictionary " 933 pages) stimulates the menstrual flow, detoxifies;
rhizoma Cyperifor sedge dried tuber rhizome, the micro-hardship of acrid in the mouth is sweet, property flat, the resolving depression of regulating the flow of vital energy, pain relieving regulating menstruation (seeing " Chinese medicine voluminous dictionary " 1672 pages).
In above-mentioned accessory drugs medical material:
rhizoma Chuanxiongfor umbrella section plant Rhizoma Chuanxiong (
ligusticum chuanxiong) rhizome, acrid in the mouth, warm in nature, can activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness.Promoting blood circulation and stopping pain (seeing " Chinese medicine voluminous dictionary " 220 pages);
fructus Viticisfor Verbenaceae wild pepper (
vitex rotundifolia) fruit, bitter in the mouth is pungent, cool in nature, can dispelling wind and heat pathogens, the clear sharp head (seeing " Chinese medicine voluminous dictionary " 2541 pages);
radix Paeoniae Albafor ranunculaceae plant Radix Paeoniae (
paeonia lactiflora) root, bitter in the mouth acid, cool in nature, have nourish blood, the effect of easing the affected liver, can control the diseases such as conjunctival congestion (seeing " Chinese medicine voluminous dictionary " 706 pages);
flos Chrysanthemifor feverfew chrysanthemum (
chrysanthemum morifolium) head inflorescence, sweet-bitter flavor, cool in nature, can dispelling wind, heat clearing away, improving eyesight, removing toxic substances (seeing " Chinese medicine voluminous dictionary " 2008 pages);
herba Menthae, for labiate Herba Menthae (
mentha haplocalyx) herb or leaf, acrid in the mouth, cool in nature, can dispelling wind, heat radiation, ward off dirty, removing toxic substances (Chinese medicine dictionary: 2648 pages); Concha Haliotidis,
semen Cassiae, for leguminous plant Semen Cassiae (
cassia tora) mature seed, bitter but sweet flavor, cool in nature, can liver heat removing, improving eyesight, diuretic, relieving constipation (seeing " Chinese medicine voluminous dictionary " 1905 pages);
fructus Evodiaefor rutaceae Fructus Evodiae (
evodia retaecarpa) immature fruit, acrid in the mouth hardship, warm in nature, poisonous, have warming middle-JIAO, pain relieving, regulate the flow of vital energy, the effect (seeing " Chinese medicine voluminous dictionary " 1118 pages) of dampness;
rhizoma Zingiberis Recens, for zingiber (
zingiberofficinale), pungent, temperature, can deliver, cold expelling, warming middle-JIAO, preventing or arresting vomiting (Nanjing Traditional Chinese Medical College compiles. traditional Chinese medical science outline. and People's Health Publisher .1958:52 page).
Above-mentioned medical material should meet the regulation under each medical material item in one of " Chinese Pharmacopoeia " nineteen ninety-five version.
The preparation method of the Chinese medicine of the treatment nervous headache disease that inventor provides is first by 4 of Scolopendras, and Scorpio 10g pulverizes, for subsequent use; Again other 9 tastes in above-mentioned 11 taste principal agents and 8 taste accessory drugs medical materials are cleaned respectively, with hot-air seasoning, be processed into fragment; Use again disinfection by ultraviolet light, after mixing by formula proportion, put into the pond that pottery or copper tank or wooden barrel or cement is built into and add water retting, and pass into steam heated to boiling 3 times, and 1～2 hour for the first time, 0.5～1 hour for the second time, 0.5 hour for the third time, so far wherein active ingredient proposed substantially; After filtering, medicinal liquid is made extractum; Fire drying in using again, pulverizes, grinds to form 60 order powder; The powder of Scolopendra, Scorpio is added to mix homogeneously; Finally pharmaceutical technology routinely, is pressed into tablet or incapsulates, and every 1g or every 1g, obtain tablet or capsule.
The above-mentioned pharmaceutical technology that is pressed into tablet comprises: 1. the 60 order powder that make are added to adjuvant, main adjuvant is adhesive modified starch, mix homogeneously; 2. in mixed powder, add water as wetting agent, make soft material; 3. soft material extruding is sieved, granulation; 4. granule is through super-dry, make its moisture be applicable to and evenly, grain graininess is suitable; 5. dried particles, through inspection, confirms to meet the requirement of tablet; 6. extrude tablet with Chong Yashi or rotary tablet machine, what be up to the standards is finished product.
The pharmaceutical technology of above-mentioned capsule comprises: 1. prepare or buy the capsulae vacuus taking gelatin as primary raw material; 2. the 60 order powder that make are crossed to sieve No. 6, the fine powder obtaining is for subsequent use; 3. enter soft capsule with the artificial medicated powder of loading, or pack medicated powder into automatic filling machine; 4. the effective ingredient to medicated powder and quality are tested, and the qualified rear glue with gelatin, in the sealing of capsule capping place, obtains finished product.
Inventor points out: this Chinese medicine also can be prepared into any conventional peroral dosage form by conventional method of Chinese medicinal.No matter which kind of dosage form, all must deposit according to the relevant regulations of drug stock control.
The Chinese medicine using method for the treatment of nervous headache disease of the present invention is oral, warm water delivery service, every day 2 times, each 4～5/sheet.
The Chinese medicine for the treatment of nervous headache disease of the present invention is tested application clinical, and treatment nervous headache disease patient 17 examples, all achieve good results.Model case has:
Case one: Nie Cuicui, female, 43 years old, people from Bijie City, Guizhou Province.Suffer from a private prosecution pain about 10 years.Once multi-treatment and lose effect, is diagnosed as refreshing smart headache through Guiyang Medical College inspection, hospitalization ten days, alleviate to some extent, due to economic cause, leave hospital and take Western medicine and treatment by Chinese herbs.Since 2009, the aggravation of headache phenomenon, every other day, will pain analgesic, a pain killer injection all can not solve pain.Observation patient expresses one's feelings thin at ordinary times, and one's eyes are lustreless, and blood pressure is at 125/75 ㎜, pale tongue, pulse condition stringy and thready pulse and puckery, is decided to be nervous headache according to theory of Chinese medical science, take medicine of the present invention after 5 days, pain obviously alleviates, and takes continuously 20 days, this elimination of pain perception, in order to consolidate curative effect, serve on 40 days, symptom is all eliminated, after 2 years, follow up a case by regular visits to, not recurrence.
Case two: Gong Dinglun, 54 years old, peasant, lived Bijie City seven-star and closes Cha He town, district.Patient's private prosecution, from 1998, is found headache, repeatedly shows effect the several years, once takes multiple analgesic, and analgesic can be alleviated originally.2003 start, with the dry vomiting of the heart, and two tops, sustainable 4-5 days sometimes shows effect, once be refreshing smart headache at many examination in hospital, after change into and take medicine of the present invention after 15 days, pain obviously alleviates, and serve on 17 days, pain all disappears, and after 1 year, with anti-, does not recur.
Case three: the jade of passing away, 38 years old, Cha He people from town, Bijie City, Guizhou Province.Patient for a long time, once took headache tablets at several years of once having a headache, and peace is to wait various analgesic quietly, originally can also pain relieving, produced afterwards Drug resistance, and have to go to hospital to make electroencephalogram, the inspections such as head film making, all no abnormal, face and be often diagnosed as refreshing smart headache, but in hospital treatment poor effect.By the agency of, changes and takes medicine of the present invention after 6 days, and symptom alleviates, and is used in conjunction headache in 27 days and all disappears, and follows up a case by regular visits to, not recurrence after 1 year.
The Chinese medicinal material for the treatment of nervous headache disease of the present invention is easy to get, and easy to process, curative effect is obvious, is applicable to the patient of the nervous headache disease for the treatment of the various causes of disease.
Detailed description of the invention
embodiment1
Chinese medicine according to the following step preparation treatment nervous headache disease:
First be about to 4 of Scolopendras, Scorpio 10g pulverizes, for subsequent use; Again 11 taste principal agents in formula and 8 taste accessory drugs medical materials are cleaned respectively, with hot-air seasoning, be processed into fragment; Use again disinfection by ultraviolet light.Then get principal agent: Herba Asari 4g, Radix Angelicae Sinensis 30g, Flos Carthami 8g, Radix Saposhnikoviae 12g, Rhizoma Et Radix Notopterygii 8g, Radix Rehmanniae Preparata 10g, Gypsum Fibrosum 30g, Caulis Polygoni Multiflori 15g, Rhizoma Cyperi 20g; Get again accessory drugs: Rhizoma Chuanxiong 30g, Fructus Viticis 7g, Radix Paeoniae Alba 6g, Flos Chrysanthemi 12g, Herba Menthae 10g, Concha Haliotidis 20g, Fructus Evodiae 8g, Rhizoma Zingiberis Recens 10g; After mixing, put into wooden barrel and add water retting, and pass into steam heated to boiling 3 times, 2 hours for the first time, 1 hour for the second time, 0.5 hour for the third time, so far wherein active ingredient proposed substantially; After filtering, medicinal liquid is made extractum; Fire drying in using again, pulverizes, grinds to form 60 order powder; The powder of Scolopendra, Scorpio is added to mix homogeneously; Finally pharmaceutical technology routinely, is pressed into tablet, and every 1g, obtains tablet product.
embodiment 2
Preparation process is with embodiment 1.Grind to form 60 object drug powders, finally pharmaceutical technology routinely, incapsulates, and every 1g, obtains capsule product.
Claims (2)
1. treat a Chinese medicine for nervous headache disease, it is characterized in that this Chinese medicine is formulated by 11 taste principal agents and 8 taste accessory drugss, the quality of medicinal material proportioning of every potion Chinese medicine is:
Principal agent: Herba Asari 4g, Radix Angelicae Sinensis 30g, Flos Carthami 8g, Radix Saposhnikoviae 12g, Rhizoma Et Radix Notopterygii 8g, Radix Rehmanniae Preparata 10g, Gypsum Fibrosum 30g, Caulis Polygoni Multiflori 15g, 4 of Scolopendras, Scorpio 10g, Rhizoma Cyperi 20g;
Accessory drugs: Rhizoma Chuanxiong 30g, Fructus Viticis 7g, Radix Paeoniae Alba 6g, Flos Chrysanthemi 12g, Herba Menthae 10g, Concha Haliotidis 20g, Fructus Evodiae 8g, Rhizoma Zingiberis Recens 10g.
2. prepare the method for Chinese medicine described in claim 1, it is characterized in that first, by 4 of Scolopendras, Scorpio 10g pulverizes, for subsequent use; Again other 9 tastes in above-mentioned 11 taste principal agents and 8 taste accessory drugs medical materials are cleaned respectively, with hot-air seasoning, be processed into fragment; Use again disinfection by ultraviolet light, after mixing by formula proportion, put into the pond that pottery or copper tank or wooden barrel or cement is built into and add water retting, and pass into steam heated to boiling 3 times, and 1～2 hour for the first time, 0.5～1 hour for the second time, 0.5 hour for the third time, so far wherein active ingredient proposed substantially; After filtering, medicinal liquid is made extractum; Fire drying in using again, pulverizes, grinds to form 60 order powder; The powder of Scolopendra, Scorpio is added to mix homogeneously; Finally pharmaceutical technology routinely, is pressed into tablet or incapsulates, and every 1g or every 1g, obtain tablet or capsule.
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| CN104645074A (en) * | 2013-11-21 | 2015-05-27 | 朱亶斌 | Traditional Chinese medicine for treating neuropathic headache |
| CN104784517A (en) * | 2015-04-27 | 2015-07-22 | 龚灿锋 | Traditional Chinese medicine for treating nerve headache |
| CN105853892A (en) * | 2016-06-07 | 2016-08-17 | 佛山市朗达信息科技有限公司 | Traditional Chinese medicine composition and preparation for treating nerve headache and preparing method thereof |
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