CN116077613A - A traditional Chinese medicine preparation for treating spleen-stomach disease and its preparation method and application - Google Patents

Abstract

The traditional Chinese medicine preparation of the invention relates to a traditional Chinese medicine formula for regulating cold and cold spleen and stomach, stagnation of spleen and stomach, upward reversal of stomach qi, bile reflux gastritis, atrophic gastritis, gastric ulcer and other spleen and stomach diseases and cervical spondylosis. Specifically, it is a Chinese patent medicine preparation prepared from Chinese herbal medicines as raw materials, as well as the specific raw material formula of the medicine, the usage amount of each component, the specific production process steps and processing methods. A traditional Chinese medicine for treating cervical spondylosis protected by the present invention includes the following components: bletilla striata, golden fruit olive, huaishan, gorgon, poria cocos, white peony root, atractylodes macrocephala, coix seed, dandelion, forsythia, Cyperus cyperi, cinnamon, roasted licorice , tangerine peel, dried ginger.

Description

A traditional Chinese medicine preparation for treating spleen-stomach disease and its preparation method and application

This application is a divisional application with an application date of August 25, 2016, an application number of 201610725392.7, and an invention title of "A Traditional Chinese Medicine Preparation and Preparation Method for Treating Spleen and Stomach Diseases".

technical field

The invention relates to a traditional Chinese medicine formula for treating gastritis, gastric ulcer and various diseases of the spleen and stomach, specifically a Chinese patent medicine preparation prepared from Chinese herbal medicines as raw materials, as well as the specific raw material formula of the medicine and the usage amount of each component, Specific production process steps and processing methods.

Background technique

With the continuous development of people's living standards and technology, modern people's living standards are improving day by day. Due to long-term emotional distress and improper diet, spleen and stomach diseases have become a common phenomenon, including chronic gastritis, atrophic gastritis, Stomach pain and bloating, early gastric cancer, etc., so timely prevention and treatment are required.

As we all know, Chinese medicine is a broad and profound medicine, which has a good effect on the prevention and treatment of some chronic diseases and the maintenance of human health. At the same time, compared with Western medicine, Chinese medicine has a wide variety of diagnosis and treatment methods, less side effects, and the curative effect of treating both symptoms and root causes Many chronic disease patients and working-class people in a sub-health state prefer to use traditional Chinese medicine to prevent and treat diseases, or to regulate sub-health.

Spleen and stomach diseases in Western medicine include superficial gastritis, chronic gastritis, gastric ulcer, duodenal ulcer, atrophic gastritis, gastric distension, gastric pain, gastric pantothenic acid, gastric gas reversed and other gastrointestinal diseases. Patients may have different degrees of indigestion Symptoms include upper abdominal discomfort and dull pain after eating, accompanied by belching, nausea, pantothenic acid, and occasional vomiting. In traditional Chinese medicine, it belongs to the categories of "epigastric pain", "fullness", "sour swallowing", "noisy" and "loss of appetite". The present invention is based on the principle of "preventive treatment of disease" in traditional Chinese medicine, "the kidney is the foundation of the innate, and the spleen and stomach are the foundation of the acquired." Starting from the pathogenesis of spleen and stomach diseases, early intervention prevention and treatment from the source of the disease can ensure the health of the body. health.

purpose of invention

The traditional Chinese medicine preparation of the present invention adopts traditional Chinese medicine to regulate the middle burner, and is effective for coldness of the spleen and stomach, stagnation of the spleen and stomach, upward reversal of stomach qi, bile reflux gastritis, atrophic gastritis and gastric ulcer. So as to achieve the purpose of slowing down and treating spleen and stomach diseases. After more than ten years of clinical trials, the present invention has very remarkable effect. It can not only effectively treat spleen and stomach diseases, but also comprehensively regulate various organs of the human body, especially the heart, brain, liver, kidney, and spleen, and reverse its pathological mechanism. Thus stepping into the best treatment effect of fundamental treatment, overall recovery, standard rate and treatment, and the overall curative effect of preventing the decline of body function and improving the body's resistance and immunity. Another object of the present invention is to provide the production process and preparation method of the medicine.

content of the invention

The invention discloses a new formula and preparation method of Chinese patent medicine for treating spleen and stomach diseases. It adopts 100% roots, stems, leaves, flowers, fruits, seeds, fungi, insects and minerals of Chinese herbal medicines, washes them, and bakes them. Drying, processing and other processes, under sterile and dust-free conditions, Chinese herbal medicines are separately crushed with a Chinese medicine grinder, sieved with an 800-mesh sieve, and blended according to the proportion. Then it is a series of pure traditional Chinese medicine products that are extracted, concentrated, separated, dried, granulated, and packaged by modern pharmaceutical technology. It guarantees all the characteristics of the original Chinese herbal decoction pieces, and can satisfy the needs of doctors in treating syndromes based on syndrome differentiation. It has strong medicinal properties and high efficacy. At the same time, it does not require decoction, can be directly taken directly, takes less amount, has rapid action, complete ingredients, and curative effect. Accurate, safe and hygienic, convenient to carry and store, easy to adjust and suitable for industrial production and many other advantages.

Considering that patients with spleen and stomach diseases generally have weak spleen and stomach and are not easy to digest capsules and pills, the Chinese medicine mixed powder can be made into granule dosage form, which is convenient to take, has stable and long-lasting curative effect, complete treatment effect, no toxic side effects, and is easy to carry.

Component A is as follows: Bletilla striata, golden fruit olive, Huaishan, Gorgon fruit, Poria cocos, white peony root, Atractylodes macrocephala, coix seed each 15 parts, dandelion, forsythia, Cyperus cyperi, cinnamon, roasted licorice, tangerine peel 10 parts, dried ginger 8 parts share.

Component B is as follows: each part of ginger is mixed with 2/5 parts of washed, mashed and twisted juice, and each part of flour is mixed with 1/5. Among them, the auxiliary material is sweet citrus essence without sucrose, which has a better taste, and the sugar content does not affect diabetic patients.

The present invention is also characterized in that on the basis of claim 1, 15 parts of pinellia song, pungent in nature, sweet and warm, can enhance the effects of relieving cough and resolving phlegm, relieving asthma and reducing adverse reactions, harmonizing the stomach, relieving vomiting, and dispelling mass.

The present invention is also characterized in that on the basis of claim 2, 10 parts each of amomum and woody incense are added, which mainly play a role in following the spleen to control the rising qi and lowering the stomach qi.

The present invention is also characterized in that on the basis of claim 3, 10 parts of Bupleurum bupleurum, 10 parts of Citrus aurantium, and 8 parts of cassia twig have the effects of soothing the liver and regulating qi, harmonizing the stomach, relieving pain, invigorating the spleen, and removing blood stasis. Dynamic recovery of meridian regulation function.

The feature of the present invention is also to add on the basis of claim 4: 10 parts of cuttlefish bone, anti-tumor, anti-ulcer and other effects, and 30 parts of astragalus, 15 parts of ginseng, which can strengthen Qi and blood, anti-aging and anti-aging, and enhance human immunity Ability to prevent and treat early gastric cancer and prolong life.

According to some theories and practices of traditional Chinese medicine, it has been proved that several medicinal materials are boiled together, and the effect is not exactly the same as that of the simple formula of granules. toxicity. Therefore, the present invention is characterized in that bletilla striata, golden fruit olive, huaishan, gorgon, white peony root, atractylodes macrocephala, coix seed, forsythia, cuttlefish bone, Cyperus cyperi, roasted licorice, etc. are jointly decocted and concentrated to extract and strengthen their active ingredients.

The medicine taking method of the present invention is: 2-3 times every day, each 6 grams, take half an hour after meal. Half a month is a course of treatment, and the duration of continuous medication is determined according to the patient's constitution, duration of illness, and repair effect. Usually avoid spicy, cold and hard food and so on. Stomach disease focuses on maintenance. It requires a regular diet, regular work and rest, light food, and reasonable proportions. Eat more food that nourishes the stomach, such as millet porridge, pasta, etc.

The effect of the invention

The treatment of spleen and stomach diseases is a long-term recuperation and treatment process. In traditional Chinese medicine, spleen and stomach diseases are "three-point treatment and seven-point recuperation". The Chinese patent medicine of this invention starts from the root cause of spleen and stomach diseases, comprehensively regulates the spleen, stomach and various viscera, and treats the slow process from the original decline of spleen and stomach function to the normalization of various organs of the human body, especially the regulation of spleen, stomach, liver and kidney functions is more obvious . After taking 2-3 courses of treatment (one course of treatment is 1 month), the Chinese patent medicine of this invention can fundamentally reverse the pathogenesis of spleen and stomach disease, make the meridians of the body unobstructed, qi and blood full, and at the same time supplement the essential nutrients needed by the human body. A variety of substances, mainly containing more than 30 kinds of amino acids, more than 20 kinds of trace elements and more than 10 kinds of minerals. Have: 1, treat both symptoms and root causes. It breaks through the limitations of traditional treatment. While treating cervical spondylosis, the drug can suppress the lesions of important viscera such as spleen, stomach, liver and kidney to the greatest extent, and improve the overall health. 2. Invigorating the spleen and nourishing the stomach breaks the traditional treatment only to eliminate inflammation symptoms, and proceeds from the principle of mutual generation and restraint of each viscera corresponding to metal, wood, water, fire and earth, and conducts overall treatment. 3. The comprehensive treatment of Chinese patent medicine breaks the conventional tactics. It uses a variety of medicines to take care of the whole body, improve the circulation of Qi and blood, correct the balance of Yin and Yang, and aim at the smooth circulation of Qi and blood in the whole body from the upper, middle and lower three points.

Specific implementation process

The specific preparation and production steps and process methods of the present invention and the specific process conditions for implementing the technical solution, wherein the steps include selection of Chinese herbal medicine → processing of Chinese herbal medicine → processing and extraction of active ingredients of Chinese herbal medicine → concentration of medicinal liquid → blending of auxiliary materials → drying → particle processing → quality Check → Pack, as follows:

Step 1: Select the medicine of high quality according to the formula ratio in claim 1, and weigh each medicine according to the weight ratio.

Step 2: Process the selected Chinese herbal medicine in step 1, and all the pure Chinese herbal medicine raw materials are washed and dried.

Step 3: Slice the Radix Paeoniae Alba and Radix Paeoniae Alba into slices, spray with rice vinegar, and stir-fry slightly with a slow fire for later use.

Step 4: Wash the cuttlefish bones, dry them in the sun, smash them into small pieces, then dry the inner shell and stir-fry them with a slow fire until they are yellow; or put them in a jar, calcinate them until they are burnt black, take them out and let them cool.

Step 5: Stir-fry Atractylodes macrocephala: Sprinkle the honey-roasted bran into the hot pot, add Atractylodes macrocephala slices when it smokes, fry until it is burnt yellow and release the burnt aroma, take it out, and sieve off the honey-roasted bran. For every 100 parts of Atractylodes macrocephala slices, 10 parts of bran are roasted with honey.

Step 6: Bletilla striata, golden fruit olive, Huaishan, gorgon, white peony root, Atractylodes macrocephala, coix seed, forsythia, cuttlefish bone, Cyperus cyperus, roasted licorice and dried ginger are decocted together to extract and strengthen their active ingredients.

Step 7: Concentrate the medicinal liquid in step 6, use a water jet pump to extract air and concentrate under reduced pressure, reduce the pressure in the evaporator, and conduct evaporation and concentration at a pressure lower than 1 atmosphere.

Step 8: Under aseptic and dust-free conditions, other Chinese herbal medicines processed in step 2 are sliced and pulverized respectively with a Chinese medicine pulverizer, then ground into powders, passed through a 800-mesh sieve and mixed into fine powders for later use; The prepared Chinese herbal medicine is Poria cocos, dandelion, cinnamon, tangerine peel or Poria cocos, dandelion, cinnamon, tangerine peel and ingredients of increasing prescription; One or more than two kinds of ginseng.

Step 9: Processing of pinellia koji, take half of raw pinellia and half of French pinellia, grind into powder, and sieve with an 800-mesh sieve. For every 10 servings, use 8 servings of ginger, wash, mash and grind the juice, 4 servings of the same flour, mix with warm water to make a thin paste, pour it into pinellia powder and knead it into a ball, after fermentation, press it into small pieces with a wooden model, Dry it and grind it into a fine powder, and put it in a dry place to prevent mildew.

Step 10: Preparation of excipients. The choice of excipients is sucrose-free sweet citrus essence combined with millet boiled rice oil extract, which not only strengthens the effect of invigorating the stomach and spleen, but also does not affect the consumption of diabetic patients.

Step 11: Drying. Because the auxiliary materials have a large amount of water, they should be dried in a cool place or dried in an oven before use.

Step 12: Granule processing, using granule processing equipment to continuously add and mix the above auxiliary materials and concentrated liquid, add pinellia koji in proportion during the process, shake and sieve continuously, and finally form uniform sized granules and dry them.

Step thirteen: Quality inspection, check the process and the quality of the particles in the process of making the particles.

Step 14: Packing, put the finished granules in airtight containers or plastic bags and seal them to prevent moisture, high temperature and pests.

The present invention provides an application of the composition described in the above technical scheme in the preparation of Chinese patent medicine for treating spleen-stomach disease. Various substances necessary for the human body.

Preferably, the application includes any one or more than two of the following (1) to (3):

(1) Inhibit the pathological changes of spleen, stomach, liver and kidney important viscera;

(2) Based on the principle of mutual generation and mutual restraint corresponding to each viscera of metal, wood, water, fire and earth, overall regulation;

(3) Overall recuperation, improving Qi and blood circulation, correcting the balance of yin and yang, and aiming at unobstructed Qi and blood circulation in the whole body from the upper, middle and lower three points.

The present invention also provides an application of the composition described in the above technical solution in the preparation of a Chinese patent medicine for treating cervical spondylosis.

Although the foregoing embodiment has described the present invention in detail, it is only a part of the embodiments of the present invention, rather than all embodiments, and people can also obtain other embodiments according to the present embodiment without inventive step, these embodiments All belong to the protection scope of the present invention.

Claims (9)

1. The composition for treating spleen and stomach diseases is characterized by comprising the following components in parts by mass:

the component A comprises: 15 parts of bletilla striata, 15 parts of radix tinosporae, 15 parts of radix polygoni multiflori, 15 parts of semen euryales, 15 parts of poria cocos, 15 parts of white paeony root, 15 parts of bighead atractylodes rhizome, 15 parts of coix seed, 10 parts of dandelion, 10 parts of fructus forsythiae, 10 parts of rhizoma cyperi, 10 parts of cinnamon, 10 parts of honey-fried licorice root, 10 parts of dried orange peel and 8 parts of dried ginger;

the component B is as follows: 2/5 parts of ginger is added to each part of ginger, the juice is smashed, 1/5 parts of flour is added to each part of ginger, and the auxiliary material is selected as sweet orange essence without sucrose.

2. The composition of claim 1, further comprising 15 parts of pinellia ternate.

3. The composition of claim 2, further comprising 10 parts of fructus amomi and 10 parts of elecampane.

4. The composition of claim 3, further comprising 10 parts of bupleurum, 10 parts of immature bitter orange and 8 parts of cassia twig.

5. The composition of claim 4, further comprising 10 parts of cuttlefish bone, 30 parts of astragalus and 15 parts of ginseng.

6. A process for the preparation of a composition as claimed in any one of claims 1 to 5, comprising the steps of:

step one: selecting the medicines according to the formula proportion and the mass multiplication in the claim 1, and weighing the medicines according to the weight part ratio;

step two: processing the Chinese herbal medicines selected in the first step, and cleaning and drying all the pure Chinese herbal medicine raw materials;

step three: slicing radix Paeoniae alba and radix Paeoniae alba, spraying with rice vinegar, and parching with slow fire;

step four: brushing and cleaning cuttlefish bone, sun drying, crushing into small pieces, drying the inner shell, and parching with slow fire to yellow; or placing in a jar, calcining to brown, taking out, and cooling;

step five: stir-frying white atractylodes rhizome: spreading honey-fried bran into a hot pot, adding Atractylodis rhizoma tablet when smoking, parching to brown, escaping Jiao Xiangqi, taking out, and sieving to remove honey-fried bran; 10 parts of bran is roasted by honey per 100 parts of bighead atractylodes rhizome slices;

step six: decocting rhizoma Bletillae, radix tinosporae, rhizoma Dioscoreae, semen euryales, radix Paeoniae alba, atractylodis rhizoma, coicis semen, fructus forsythiae, os Sepiae, rhizoma Cyperi, and radix Glycyrrhizae Preparata, and enhancing effective components;

step seven: concentrating the liquid medicine in the step six, adopting a water flow jet pump to pump air and decompress and concentrate, reducing the pressure in an evaporator, and performing evaporation concentration under the pressure lower than 1 atmosphere;

step eight: slicing and pulverizing the other processed Chinese herbal medicines in the second step under the aseptic and dust-free conditions respectively by using a Chinese herbal medicine pulverizer, grinding into powder, and sieving with a 800-mesh sieve to mix into fine powder for later use;

step nine: processing rhizoma Pinelliae Preparata, pulverizing rhizoma Pinelliae Preparata and rhizoma Pinelliae Preparata into powder, and sieving with 800 mesh sieve; every 10 parts, cleaning 8 parts of ginger, mashing and mincing juice, mixing 4 parts of flour with warm boiled water to form thin paste, pouring the thin paste into pinellia tuber powder, kneading the thin paste into blocks, fermenting, pressing the blocks into small blocks by using a wooden model, airing the blocks, and grinding the blocks into fine powder, wherein the blocks are suitable for being placed in a drying place for mildew prevention;

step ten: blending auxiliary materials, wherein the auxiliary materials are selected from rice oil extracts prepared by decocting sugar-free sweet orange essence and millet, so that the stomach strengthening and spleen benefiting effects are enhanced, and the taking of diabetics is not influenced by the sweet orange essence;

step eleven: drying, wherein the auxiliary materials with larger water content are put in a shade place for drying in the shade or can be used after being dried in an oven;

step twelve: and (3) processing particles, namely continuously feeding and mixing the auxiliary materials and the concentrated solution by using particle processing equipment, adding the pinellia tuber yeast according to a proportion in the process, continuously swinging and sieving, and finally forming particles with uniform size and drying.

7. The use of the composition according to any one of claims 1 to 5 or the Chinese composition prepared by the preparation method of claim 6 in the preparation of a Chinese patent medicine for treating spleen and stomach diseases, wherein the use radically and thoroughly reverses pathogenesis of the spleen and stomach diseases, so that channels and collaterals of a body are unobstructed, qi and blood are full, and meanwhile, a plurality of substances necessary for a human body are supplemented.

8. The use according to claim 7, comprising any one or two or more of the following (1) to (3):

(1) Inhibiting pathological changes of important viscera of spleen, stomach, liver and kidney;

(2) Based on the principle of corresponding to viscera of Jin Mushui fire, the whole body is treated;

(3) The whole body is maintained, the qi and blood circulation is improved, the balance of yin and yang is corrected, and the qi and blood circulation of the whole body is smooth from the upper, middle and lower three-way.

9. Use of a composition according to any one of claims 1 to 5 or a composition according to claim 6 in the preparation of a Chinese patent medicine for the treatment of cervical spondylosis.