CN116077613A

CN116077613A - Traditional Chinese medicine preparation for treating spleen and stomach diseases and preparation method and application thereof

Info

Publication number: CN116077613A
Application number: CN202310026281.7A
Authority: CN
Inventors: 董琴
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-08-25
Filing date: 2016-08-25
Publication date: 2023-05-09
Also published as: CN107773739A

Abstract

The invention relates to a traditional Chinese medicine preparation, which relates to a traditional Chinese medicine formula for conditioning spleen and stomach diseases such as cold and cool spleen and stomach, spleen and stomach stagnation, stomach qi upward reversal, bile reflux gastritis, atrophic gastritis, gastric ulcer and the like and cervical spondylosis. In particular to a Chinese patent medicine preparation prepared by taking Chinese herbal medicines as raw materials, a specific raw material medicine formula of the medicine, the use amount of each component, specific production flow steps and a specific technological processing method. The invention provides a traditional Chinese medicine for treating cervical spondylosis, which comprises the following components: bletilla striata, tinospora root, huishan, gorgon fruit, poria cocos, white peony root, bighead atractylodes rhizome, coix seed, dandelion, fructus forsythiae, nutgrass galingale rhizome, cinnamon, honey-fried licorice root, dried orange peel and dried ginger.

Description

Traditional Chinese medicine preparation for treating spleen and stomach diseases and preparation method and application thereof

The application is a divisional application of a Chinese medicinal preparation for treating spleen and stomach diseases and a preparation method thereof, wherein the application date is 25 of 2016 and 08, the application number is 201610725392.7.

Technical Field

The invention relates to a traditional Chinese medicine formula for treating gastritis, gastric ulcer and various spleen and stomach diseases, in particular to a traditional Chinese medicine preparation prepared by taking Chinese herbal medicines as raw materials, and a specific raw material medicine formula, the use amount of each component, specific production flow steps and a specific technological processing method of the medicine.

Background

With the continuous development of the living standard and science and technology of people, the living level of modern people is improved day by day, and diseases of spleen and stomach become common phenomena due to long-term emotional disturbance, improper diet and the like, wherein the diseases comprise chronic gastritis, atrophic gastritis, gastralgia and gastrectasia, early gastric cancer and the like, so that the diseases need to be prevented and treated in time.

As is well known, the traditional Chinese medicine is a profound medicine, has good effects of preventing and treating some chronic diseases and keeping human health, and meanwhile, compared with the western medicine, the diagnosis and treatment method of the traditional Chinese medicine has the curative effects of various kinds, small side effects and treatment of both principal and secondary aspects of diseases, and many chronic disease patients and the work and salary class in sub-health state prefer to prevent and treat diseases or condition sub-health state by using traditional Chinese medicine.

Spleen stomach diseases in western medicine include superficial gastritis, chronic gastritis, gastric ulcer, duodenal ulcer, atrophic gastritis, gastrectasia, gastralgia, gastric pantothenic acid, upward reverse stomach qi and other gastrointestinal diseases, patients can have different degrees of dyspepsia symptoms, and after eating, the patients can suffer from discomfort of upper abdomen, hidden pain, belch, nausea, pantothenic acid and occasional vomiting. In the traditional Chinese medicine, the Chinese medicine belongs to the categories of epigastric pain, distention and fullness, acid regurgitation, noisy, anorexia and the like. The invention is based on the principle of ' treating disease ' in traditional Chinese medicine, the kidney is the congenital origin, the spleen and stomach is the acquired origin ', and the disease source of the disease is used for early intervention prevention and treatment based on the pathogenesis principle of the spleen and stomach disease, so that the health of the body can be ensured.

Object of the Invention

The traditional Chinese medicine preparation adopts traditional Chinese medicines to condition middle energizer, and is used for treating spleen-stomach cold, spleen-stomach stagnation, gastric qi upward reversal, bile reflux gastritis, atrophic gastritis and gastric ulcer. Thereby achieving the purpose of slowing down and treating spleen and stomach diseases. The invention has remarkable clinical trial effect for more than ten years, can effectively treat spleen and stomach diseases, can comprehensively regulate all organs of human body, particularly regulate the whole body of heart, brain, liver, kidney and spleen, and reverse pathological mechanism, thereby stepping into the best treatment effects of radical treatment, integral recovery and standard rate treatment, and has the integral curative effects of preventing body function from being reduced and improving human body resistance and immunity. Another object of the invention is to provide a process for the manufacture and a method for the preparation of the medicament.

Summary of the invention

The present invention discloses a Chinese medicine prescription for curing spleen and stomach diseases and its preparation method, which is made up by using 100% of Chinese medicinal materials of root, stem, leaf flower, fruit, seed, fungus, insect and mineral substance through the processes of cleaning, drying and processing, etc. under the condition of sterility and dust-free, using Chinese medicinal pulverizer to respectively pulverize Chinese medicinal materials, sieving with 800 meshes sieve, mixing them uniformly according to a certain proportion. Then extracting, concentrating, separating, drying, granulating, packaging and refining to obtain pure Chinese medicinal product series. The traditional Chinese medicine decoction piece guarantees all characteristics of the original traditional Chinese medicine decoction piece, can meet the requirement of doctors for treatment based on syndrome differentiation, is modified according to syndrome, has strong medicine property and high medicine effect, and has the advantages of no need of decoction, direct administration, small dosage, rapid effect, complete ingredients, definite curative effect, safety and sanitation, convenient carrying and storage, easy modulation, suitability for industrial production and the like.

Considering that the spleen and stomach of the spleen and stomach patient are generally weak, capsules and pills are difficult to digest, the traditional Chinese medicine mixed powder can be prepared into a granular formulation, is convenient to take, has stable and durable curative effect, has thorough curative effect, has no toxic or side effect and is convenient to carry.

Wherein component A is as follows: 15 parts of bletilla striata, tinospora root, huishan, gorgon euryale seed, poria cocos, white peony root, bighead atractylodes rhizome, coix seed, 10 parts of dandelion, fructus forsythiae, nutgrass galingale rhizome, cinnamon, honey-fried licorice root, dried orange peel and 8 parts of dried ginger.

Wherein component B is as follows: the ginger is mixed with 2/5 parts of cleaning mashed juice per part, and the flour is mixed with 1/5 parts per part. Wherein the auxiliary material is sweet orange essence without sucrose, has better taste, and the sugar content does not affect diabetics.

The invention is further characterized by the addition of the following claims 1: pinellia tuber, rhizoma Pinelliae-koji 15 parts, with pungent and sweet nature, has the effects of enhancing the effects of relieving cough and reducing sputum, relieving asthma and lowering adverse flow of qi, harmonizing stomach and arresting vomiting, and relieving stuffiness and resolving masses.

The invention is further characterized by the addition of the following claims 2: fructus Amomi and radix aucklandiae, each 10 parts, are effective in regulating spleen and ascending qi, and reducing stomach qi.

The invention is further characterized by the addition of the following claims 3: 10 parts of bupleurum, 10 parts of immature bitter orange and 8 parts of cassia twig, has the effects of soothing liver, regulating qi, harmonizing stomach, relieving pain, strengthening spleen and removing blood stasis, and can dynamically restore the blood circulation and regulate the channels and collaterals.

The invention is further characterized by the addition of the following claims 4: 10 parts of cuttlefish bone, 30 parts of astragalus mongholicus, 15 parts of ginseng, and the effects of resisting tumors, ulcers and the like, can strengthen the effects of tonifying qi and blood, resisting aging, enhancing the immunity of human bodies, preventing and treating early gastric cancer diseases and prolonging life.

According to some theories and practices of traditional Chinese medicine, the medicines are decocted together, the effect of the decoction is not completely the same as that of the simple granule formulation, the curative effect of the decoction together is obviously stronger than that of the granule after being simply mixed, and the toxicity of some medicines can be greatly reduced. Therefore, the invention is characterized in that the effective components of the Chinese medicinal materials are extracted and enhanced by common decoction and concentration of the common materials such as bletilla striata, tinospora root, huaishan, gorgon fruit, white paeony root, largehead atractylodes rhizome, coix seed, weeping forsythiae capsule, cuttlefish bone, nutgrass galingale rhizome, honey-fried licorice root and the like.

The medicine taking method of the invention comprises the following steps: is administered after half an hour after meal, 2-3 times per day, 6 g each time. Half a month is a treatment course, and the duration of taking medicine is determined according to the constitution and the disease duration of a patient and the repairing effect. It is often contraindicated to eat spicy, chilled foods, etc. The stomach disease is cured, the diet is required to have a festival, the food is light, the proportion is reasonable, and the stomach nourishing food is eaten more, such as millet porridge, cooked wheaten food and the like.

ADVANTAGEOUS EFFECTS OF INVENTION

The treatment of the spleen and stomach diseases is a long-term recuperation treatment process, and the ' three-branch treatment and the ' seven-branch recuperation ' of the spleen and stomach diseases are taught in the traditional Chinese medicine. The Chinese patent medicine starts from the root cause of the spleen and stomach diseases, comprehensively regulates spleen and stomach and viscera, treats the original spleen and stomach function decline until each organ of the human body is in a slow process, and particularly has obvious regulation and treatment on spleen and stomach, liver and kidney functions. After the Chinese patent medicine is taken for 2-3 treatment courses (1 treatment course is 1 month), the pathogenesis of spleen and stomach diseases is thoroughly reversed fundamentally, so that the channels and collaterals of the body are unobstructed, qi and blood are full, and meanwhile, various substances necessary for the human body are supplemented, and the Chinese patent medicine mainly contains more than 30 amino acids, more than 20 microelements and more than 10 minerals. The device comprises: 1. treat both principal and secondary aspect of disease. The traditional treatment limitation is broken through, and the medicine can inhibit the pathological changes of important viscera such as spleen, stomach, liver, kidney and the like to the maximum extent while treating cervical spondylosis, and improves the overall health. 2. Spleen-strengthening and stomach-nourishing breaks through the traditional treatment, and is only used for eliminating inflammation symptoms, and the whole treatment is carried out on the basis of the principle of the corresponding generation and restriction of viscera of Jin Mushui fire earth. 3. The Chinese patent medicine is used for comprehensively treating and breaking the conventional tactics, and aims at regulating and nourishing the whole body, improving the qi and blood circulation, correcting the balance of yin and yang and smoothening the qi and blood circulation of the whole body from the upper, middle and lower three-way.

Detailed description of the preferred embodiments

The preparation method comprises the following steps of selecting selected herbal medicines, processing the Chinese herbal medicines, processing and extracting the effective components of the Chinese herbal medicines, concentrating liquid medicine, preparing auxiliary materials, drying, processing particles, checking quality and packaging, wherein the steps comprise:

step one: selecting the medicines according to the formula proportion and the mass multiplication in the claim 1, and weighing the medicines according to the weight part ratio.

Step two: processing the Chinese herbal medicines selected in the first step, and cleaning and drying all the pure Chinese herbal medicine raw materials.

Step three: slicing radix Paeoniae alba and radix Paeoniae alba, spraying with rice vinegar, and parching with slow fire.

Step four: brushing and cleaning cuttlefish bone, sun drying, crushing into small pieces, drying the inner shell, and parching with slow fire to yellow; or placing in a normal jar, calcining to brown, taking out, and cooling.

Step five: stir-frying white atractylodes rhizome: spreading honey-fried bran into a hot pot, adding Atractylodis rhizoma tablet when smoking, parching to brown, escaping Jiao Xiangqi, taking out, and sieving to remove honey-fried bran. 10 parts of bran are roasted with honey per 100 parts of bighead atractylodes rhizome slices.

Step six: the effective components of rhizoma Bletillae, radix tinosporae, rhizoma Dioscoreae, semen euryales, radix Paeoniae alba, atractylodis rhizoma, coicis semen, fructus forsythiae, os Sepiae, rhizoma Cyperi, radix Glycyrrhizae Preparata and Zingiberis rhizoma are decocted together to extract and strengthen.

Step seven: concentrating the liquid medicine in the step six, adopting a water flow jet pump to pump air and decompress and concentrate, reducing the pressure in an evaporator, and performing evaporation concentration under the pressure lower than 1 atmosphere.

Step eight: slicing and pulverizing the other processed Chinese herbal medicines in the second step under the aseptic and dust-free conditions respectively by using a Chinese herbal medicine pulverizer, grinding into powder, and sieving with a 800-mesh sieve to mix into fine powder for later use; the other processed Chinese herbal medicines comprise Poria, herba Taraxaci, cortex Cinnamomi, pericarpium Citri Tangerinae or Poria, herba Taraxaci, cortex Cinnamomi, pericarpium Citri Tangerinae and prescription increasing components; the prescription-increasing component is one or more of fructus Amomi, radix aucklandiae, bupleuri radix, fructus Aurantii Immaturus, ramulus Cinnamomi, radix astragali and Ginseng radix.

Step nine: processing rhizoma Pinelliae Preparata, pulverizing rhizoma Pinelliae Preparata and rhizoma Pinelliae Preparata into powder, and sieving with 800 mesh sieve. Every 10 parts, 8 parts of ginger are used for cleaning, mashing and juice, 4 parts of flour and warm boiled water are mixed into thin paste, the thin paste is poured into pinellia tuber powder for kneading and agglomerating, after fermentation, the thin paste is pressed into small blocks by a wooden model, and the small blocks are dried and crushed into fine powder, and the thin paste is suitable for being placed in a dry place for mildew prevention.

Step ten: the auxiliary materials are prepared, and the auxiliary materials are selected from rice oil extracts prepared by decocting sugar-free sweet orange essence and millet, so that the effects of invigorating stomach and benefiting spleen are enhanced, and the taking of diabetics is not influenced by the sweet orange essence.

Step eleven: drying, because of the large amount of auxiliary materials, the dried materials can be put in a shady place for drying in the shade or can be used after being dried in an oven.

Step twelve: and (3) processing particles, namely continuously feeding and mixing the auxiliary materials and the concentrated solution by using particle processing equipment, adding the pinellia tuber yeast according to a proportion in the process, continuously swinging and sieving, and finally forming particles with uniform size and drying.

Step thirteen: and (5) quality inspection, namely inspecting the working procedure in the process of manufacturing the granules and the quality of the granules.

Step fourteen: packaging, and packaging the granule in a sealed container or plastic bag to prevent moisture, high temperature and insect damage.

The invention provides an application of the composition in preparing a Chinese patent medicine for treating spleen and stomach diseases, which radically and thoroughly reverses pathogenesis of the spleen and stomach diseases, enables channels and collaterals of a body to be unobstructed, enables qi and blood to be full, and supplements various substances necessary for a human body.

Preferably, the application includes any one or two or more of the following (1) to (3):

(1) Inhibiting pathological changes of important viscera of spleen, stomach, liver and kidney;

(2) Based on the principle of corresponding to viscera of Jin Mushui fire, the whole body is treated;

(3) The whole body is maintained, the qi and blood circulation is improved, the balance of yin and yang is corrected, and the qi and blood circulation of the whole body is smooth from the upper, middle and lower three-way.

The invention also provides application of the composition in preparing a Chinese patent medicine for treating cervical spondylosis.

Although the foregoing embodiments have been described in some, but not all, embodiments of the invention, it should be understood that other embodiments may be devised in accordance with the present embodiments without departing from the spirit and scope of the invention.

Claims

1. The composition for treating spleen and stomach diseases is characterized by comprising the following components in parts by mass:

the component A comprises: 15 parts of bletilla striata, 15 parts of radix tinosporae, 15 parts of radix polygoni multiflori, 15 parts of semen euryales, 15 parts of poria cocos, 15 parts of white paeony root, 15 parts of bighead atractylodes rhizome, 15 parts of coix seed, 10 parts of dandelion, 10 parts of fructus forsythiae, 10 parts of rhizoma cyperi, 10 parts of cinnamon, 10 parts of honey-fried licorice root, 10 parts of dried orange peel and 8 parts of dried ginger;

the component B is as follows: 2/5 parts of ginger is added to each part of ginger, the juice is smashed, 1/5 parts of flour is added to each part of ginger, and the auxiliary material is selected as sweet orange essence without sucrose.

2. The composition of claim 1, further comprising 15 parts of pinellia ternate.

3. The composition of claim 2, further comprising 10 parts of fructus amomi and 10 parts of elecampane.

4. The composition of claim 3, further comprising 10 parts of bupleurum, 10 parts of immature bitter orange and 8 parts of cassia twig.

5. The composition of claim 4, further comprising 10 parts of cuttlefish bone, 30 parts of astragalus and 15 parts of ginseng.

6. A process for the preparation of a composition as claimed in any one of claims 1 to 5, comprising the steps of:

step one: selecting the medicines according to the formula proportion and the mass multiplication in the claim 1, and weighing the medicines according to the weight part ratio;

step two: processing the Chinese herbal medicines selected in the first step, and cleaning and drying all the pure Chinese herbal medicine raw materials;

step three: slicing radix Paeoniae alba and radix Paeoniae alba, spraying with rice vinegar, and parching with slow fire;

step four: brushing and cleaning cuttlefish bone, sun drying, crushing into small pieces, drying the inner shell, and parching with slow fire to yellow; or placing in a jar, calcining to brown, taking out, and cooling;

step five: stir-frying white atractylodes rhizome: spreading honey-fried bran into a hot pot, adding Atractylodis rhizoma tablet when smoking, parching to brown, escaping Jiao Xiangqi, taking out, and sieving to remove honey-fried bran; 10 parts of bran is roasted by honey per 100 parts of bighead atractylodes rhizome slices;

step six: decocting rhizoma Bletillae, radix tinosporae, rhizoma Dioscoreae, semen euryales, radix Paeoniae alba, atractylodis rhizoma, coicis semen, fructus forsythiae, os Sepiae, rhizoma Cyperi, and radix Glycyrrhizae Preparata, and enhancing effective components;

step seven: concentrating the liquid medicine in the step six, adopting a water flow jet pump to pump air and decompress and concentrate, reducing the pressure in an evaporator, and performing evaporation concentration under the pressure lower than 1 atmosphere;

step eight: slicing and pulverizing the other processed Chinese herbal medicines in the second step under the aseptic and dust-free conditions respectively by using a Chinese herbal medicine pulverizer, grinding into powder, and sieving with a 800-mesh sieve to mix into fine powder for later use;

step nine: processing rhizoma Pinelliae Preparata, pulverizing rhizoma Pinelliae Preparata and rhizoma Pinelliae Preparata into powder, and sieving with 800 mesh sieve; every 10 parts, cleaning 8 parts of ginger, mashing and mincing juice, mixing 4 parts of flour with warm boiled water to form thin paste, pouring the thin paste into pinellia tuber powder, kneading the thin paste into blocks, fermenting, pressing the blocks into small blocks by using a wooden model, airing the blocks, and grinding the blocks into fine powder, wherein the blocks are suitable for being placed in a drying place for mildew prevention;

step ten: blending auxiliary materials, wherein the auxiliary materials are selected from rice oil extracts prepared by decocting sugar-free sweet orange essence and millet, so that the stomach strengthening and spleen benefiting effects are enhanced, and the taking of diabetics is not influenced by the sweet orange essence;

step eleven: drying, wherein the auxiliary materials with larger water content are put in a shade place for drying in the shade or can be used after being dried in an oven;

7. The use of the composition according to any one of claims 1 to 5 or the Chinese composition prepared by the preparation method of claim 6 in the preparation of a Chinese patent medicine for treating spleen and stomach diseases, wherein the use radically and thoroughly reverses pathogenesis of the spleen and stomach diseases, so that channels and collaterals of a body are unobstructed, qi and blood are full, and meanwhile, a plurality of substances necessary for a human body are supplemented.

8. The use according to claim 7, comprising any one or two or more of the following (1) to (3):

9. Use of a composition according to any one of claims 1 to 5 or a composition according to claim 6 in the preparation of a Chinese patent medicine for the treatment of cervical spondylosis.