CN111328290A - 用于靶向核酸编辑的基于crispr/cas-腺嘌呤脱氨酶的组合物、系统和方法 - Google Patents

用于靶向核酸编辑的基于crispr/cas-腺嘌呤脱氨酶的组合物、系统和方法 Download PDF

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CN111328290A
CN111328290A CN201880055316.7A CN201880055316A CN111328290A CN 111328290 A CN111328290 A CN 111328290A CN 201880055316 A CN201880055316 A CN 201880055316A CN 111328290 A CN111328290 A CN 111328290A
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protein
adenosine deaminase
sequence
rna
guide
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F·张
J·戈滕贝格
D·B·T·科克斯
O·阿布达耶
S·坎南
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Massachusetts Institute of Technology
Broad Institute Inc
Harvard University
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Broad Institute Inc
Harvard University
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CN201880055316.7A 2017-06-26 2018-06-26 用于靶向核酸编辑的基于crispr/cas-腺嘌呤脱氨酶的组合物、系统和方法 Pending CN111328290A (zh)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US201762525181P 2017-06-26 2017-06-26
US62/525,181 2017-06-26
US201762528391P 2017-07-03 2017-07-03
US62/528,391 2017-07-03
US201762534016P 2017-07-18 2017-07-18
US62/534,016 2017-07-18
US201762561638P 2017-09-21 2017-09-21
US62/561,638 2017-09-21
US201762568304P 2017-10-04 2017-10-04
US62/568,304 2017-10-04
US201762574158P 2017-10-18 2017-10-18
US62/574,158 2017-10-18
US201762591187P 2017-11-27 2017-11-27
US62/591,187 2017-11-27
US201762610105P 2017-12-22 2017-12-22
US62/610,105 2017-12-22
PCT/US2018/039616 WO2019005884A1 (en) 2017-06-26 2018-06-26 CRISPR / CAS-ADENINE DEAMINASE COMPOSITIONS, SYSTEMS AND METHODS FOR TARGETED NUCLEIC ACID EDITION

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US (1) US20210093667A1 (enExample)
EP (1) EP3645054A4 (enExample)
JP (2) JP7454494B2 (enExample)
KR (1) KR102761791B1 (enExample)
CN (1) CN111328290A (enExample)
AU (2) AU2018290843B2 (enExample)
CA (1) CA3064601A1 (enExample)
WO (1) WO2019005884A1 (enExample)

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CN111727247A (zh) * 2017-10-04 2020-09-29 博德研究所 用于靶向核酸编辑的系统、方法和组合物
CN112126645A (zh) * 2020-09-11 2020-12-25 广州吉赛生物科技股份有限公司 一种环形rna敲低方法及其应用
CN112877314A (zh) * 2021-03-08 2021-06-01 四川大学 一种诱导型碱基编辑系统及其应用
CN113519456A (zh) * 2021-08-27 2021-10-22 三江县连兴蛇业有限公司 一种五步蛇养殖方法
CN113667734A (zh) * 2021-07-16 2021-11-19 四川大学华西医院 Shank3片段序列甲基化检测试剂在制备精神分裂症诊断试剂盒中的用途
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CN114560946A (zh) * 2020-11-27 2022-05-31 华东师范大学 无pam限制的腺嘌呤单碱基编辑产品、方法和应用
WO2022253351A1 (zh) * 2021-06-04 2022-12-08 中国科学院脑科学与智能技术卓越创新中心 新型Cas13蛋白及其筛选方法和应用
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CN115820691A (zh) * 2022-07-25 2023-03-21 安徽农业大学 一种基于LbCpf1变体的水稻碱基编辑系统和应用
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