CN111317678A - Beautifying formula - Google Patents
Beautifying formula Download PDFInfo
- Publication number
- CN111317678A CN111317678A CN201811524489.7A CN201811524489A CN111317678A CN 111317678 A CN111317678 A CN 111317678A CN 201811524489 A CN201811524489 A CN 201811524489A CN 111317678 A CN111317678 A CN 111317678A
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- China
- Prior art keywords
- parts
- extract
- sodium hyaluronate
- ceramide
- hydrolyzed
- Prior art date
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- Pending
Links
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 24
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 24
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 24
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 claims abstract description 15
- 229940106189 ceramide Drugs 0.000 claims abstract description 15
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 claims abstract description 15
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 claims abstract description 15
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 claims abstract description 14
- 241001530056 Athelia rolfsii Species 0.000 claims abstract description 12
- OWPUOLBODXJOKH-UHFFFAOYSA-N 2,3-dihydroxypropyl prop-2-enoate Chemical compound OCC(O)COC(=O)C=C OWPUOLBODXJOKH-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 230000003796 beauty Effects 0.000 claims abstract description 7
- 239000000284 extract Substances 0.000 claims description 27
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 19
- 238000003756 stirring Methods 0.000 claims description 14
- 241000205585 Aquilegia canadensis Species 0.000 claims description 12
- 235000008331 Pinus X rigitaeda Nutrition 0.000 claims description 12
- 235000011613 Pinus brutia Nutrition 0.000 claims description 12
- 241000018646 Pinus brutia Species 0.000 claims description 12
- 239000011259 mixed solution Substances 0.000 claims description 12
- 235000020710 ginseng extract Nutrition 0.000 claims description 11
- 239000002537 cosmetic Substances 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 7
- 229940059958 centella asiatica extract Drugs 0.000 claims description 6
- 238000001816 cooling Methods 0.000 claims description 3
- 238000011049 filling Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 claims description 3
- 239000000419 plant extract Substances 0.000 claims description 2
- 230000008569 process Effects 0.000 claims description 2
- 238000009472 formulation Methods 0.000 claims 6
- 125000001549 ceramide group Chemical group 0.000 claims 1
- 230000003020 moisturizing effect Effects 0.000 abstract description 7
- 230000003647 oxidation Effects 0.000 abstract description 6
- 238000007254 oxidation reaction Methods 0.000 abstract description 6
- 230000002087 whitening effect Effects 0.000 abstract description 5
- 230000001153 anti-wrinkle effect Effects 0.000 abstract description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract description 3
- 229910052760 oxygen Inorganic materials 0.000 abstract description 3
- 239000001301 oxygen Substances 0.000 abstract description 3
- 230000008929 regeneration Effects 0.000 abstract description 3
- 238000011069 regeneration method Methods 0.000 abstract description 3
- 230000037394 skin elasticity Effects 0.000 abstract description 2
- 210000003491 skin Anatomy 0.000 description 35
- 230000000694 effects Effects 0.000 description 26
- 239000000047 product Substances 0.000 description 9
- 238000002360 preparation method Methods 0.000 description 8
- 239000004480 active ingredient Substances 0.000 description 7
- 210000004027 cell Anatomy 0.000 description 7
- 241000167550 Centella Species 0.000 description 6
- 230000001815 facial effect Effects 0.000 description 5
- 230000001965 increasing effect Effects 0.000 description 5
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 4
- KZTJQXAANJHSCE-OIDHKYIRSA-N N-octodecanoylsphinganine Chemical group CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)CCCCCCCCCCCCCCC KZTJQXAANJHSCE-OIDHKYIRSA-N 0.000 description 4
- 239000000706 filtrate Substances 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- 238000000227 grinding Methods 0.000 description 4
- 230000019612 pigmentation Effects 0.000 description 4
- 230000002829 reductive effect Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 241000221696 Sclerotinia sclerotiorum Species 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 150000003254 radicals Chemical class 0.000 description 3
- 238000005303 weighing Methods 0.000 description 3
- 230000037303 wrinkles Effects 0.000 description 3
- 241000208340 Araliaceae Species 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 2
- 235000003140 Panax quinquefolius Nutrition 0.000 description 2
- 230000032683 aging Effects 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 235000008434 ginseng Nutrition 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
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- 230000036548 skin texture Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 description 1
- FEBUJFMRSBAMES-UHFFFAOYSA-N 2-[(2-{[3,5-dihydroxy-2-(hydroxymethyl)-6-phosphanyloxan-4-yl]oxy}-3,5-dihydroxy-6-({[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-4-yl)oxy]-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl phosphinite Chemical compound OC1C(O)C(O)C(CO)OC1OCC1C(O)C(OC2C(C(OP)C(O)C(CO)O2)O)C(O)C(OC2C(C(CO)OC(P)C2O)O)O1 FEBUJFMRSBAMES-UHFFFAOYSA-N 0.000 description 1
- 229920002498 Beta-glucan Polymers 0.000 description 1
- 108030001720 Bontoxilysin Proteins 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 229920002305 Schizophyllan Polymers 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 208000030961 allergic reaction Diseases 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 229940053031 botulinum toxin Drugs 0.000 description 1
- 238000005282 brightening Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000000686 essence Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000007830 nerve conduction Effects 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000037368 penetrate the skin Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000009758 senescence Effects 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 230000008326 skin blood flow Effects 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9755—Gymnosperms [Coniferophyta]
- A61K8/9767—Pinaceae [Pine family], e.g. pine or cedar
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a beauty formula which comprises the following raw materials in parts by mass: 80-90 parts of cross-linked sodium hyaluronate, 5-8 parts of hydrolyzed sodium hyaluronate, 0.5-3 parts of ceramide, 0.5-3 parts of hydrolyzed sclerotium rolfsii gum, 0.5-3 parts of glycerol acrylate and 0.5-2 parts of hexapeptide. The product prepared by the content formula has good safety and high absorptivity, can promote cell regeneration, increase skin elasticity, resist oxidation and clear oxygen free radicals, and has remarkable whitening, moisturizing and anti-wrinkle effects.
Description
Technical Field
The invention relates to the technical field of medical cosmetology, in particular to a cosmetology formula.
Background
Due to the influence of factors such as dry and dirty air, interference of ultraviolet rays, working pressure, life rhythm and the like in a living environment, the outer layer of the skin of a human body is influenced to have the phenomena of dry and tight skin, roughness, aging, wrinkle generation, elasticity loss, large pores, dull and dull skin and the like. At present, various beauty and skin care products are full of markets, the cosmetics can clean, care and beautify the skin, however, the skin cuticle has a shielding effect, and most active ingredients in the cosmetics are difficult to penetrate the skin, so that the effects of the ingredients are influenced. The appearance of the introduction instrument overcomes the skin barrier effect, and the skin barrier effect can be overcome by matching the introduction instrument with cosmetics, so that the active ingredients are promoted to enter dermis and subcutaneous tissues through epidermis, the permeability of the locally applied active ingredients is increased, and the transdermal absorption is increased.
However, most of the skin care products used in the market together with the lead-in instrument are prepared by chemical synthesis, contain preservatives and essences, have poor compatibility with human skin, cause adverse effects when entering the skin, and have single efficacy and less absorption of active ingredients in the products by the skin.
Therefore, the formula of the beauty product which has multiple effects of moisturizing, improving cell activity, resisting oxidation and whitening, has good safety and high absorptivity and has important research significance and application value is developed.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide an introduction type beautifying formula with high safety, and the introduction type beautifying formula has multiple effects of high moisture retention, cell activity improvement, skin tightening, oxidation resistance and the like.
In order to achieve the purpose, the invention adopts the following technical scheme:
the beauty formula comprises the following raw materials in parts by mass:
80-90 parts of cross-linked sodium hyaluronate
5-8 parts of hydrolyzed sodium hyaluronate
0.5-3 parts of ceramide
0.5-3 parts of hydrolyzed sclerotium rolfsii gum
0.5-3 parts of glycerol acrylate
0.5-2 parts of hexapeptide.
Preferably, the feed comprises the following raw materials in parts by mass:
80 parts of crosslinked sodium hyaluronate
Hydrolyzed sodium hyaluronate 6 parts
Ceramide 1.5 parts
2 parts of hydrolyzed sclerotium rolfsii gum
1 part of glycerol acrylate
1.5 parts of hexapeptide.
Preferably, the plant extract comprises 5 parts of ginseng extract, 1.8 parts of pine needle water extract, 1.5 parts of honeysuckle extract and 2 parts of centella extract.
Preferably, the ceramide is ceramide II.
Preferably, the preparation method of the cosmetic formula comprises the following steps:
s1: firstly, stirring ceramide and glyceryl acrylate for 10-20min at the temperature of 60-80 ℃ until the ceramide is completely dissolved to form a uniform mixed solution, and then cooling to normal temperature;
s2: adding the hydrolyzed sclerotium rolfsii and the hexapeptide into the mixed solution in the step S1, and continuing stirring for 5-10 min;
s3: adding cross-linked sodium hyaluronate and sodium hyaluronate into the mixed solution in the step S2, and uniformly mixing;
s4: adding the ginseng extract, the pine needle water extract, the honeysuckle flower extract and the centella asiatica extract into the mixed solution in the step S3, and slowly stirring until the mixture is uniformly mixed;
s5: sterilizing and filling.
Preferably, the rotation speed during the stirring in the steps S1 and S2 is 100-300 rmp.
Preferably, the rotation speed during the stirring process of the step S3 is 100-200 rmp.
The cross-linked sodium hyaluronate in the beauty formula can form a breathable net-shaped hydrated film on the surface of skin to adjust the moisture balance of the surface of the skin, and the low-molecular hydrolyzed sodium hyaluronate can promote the repair of the skin, permeate into the deep layer of the skin, play the roles of internally moisturizing and preserving moisture and repairing damaged cells, and simultaneously can promote the absorption of active ingredients in the formula by the skin.
The formula also selects various active ingredients for synergistic promotion, the ceramide with moisturizing and antioxidant effects can inhibit active sebaceous gland secretion while perfecting sebaceous membranes, balance skin water and oil, enhance the self-protection function of skin, the hydrolyzed sclerotium rolfsii gum with the effects of moisturizing, delaying senescence and improving cell activity, the hydrolyzed sclerotium rolfsii gum (scleroglucan) is hydrolyzed β -glucan decomposed from sclerotium rolfsii which is a fungus plant, namely sclerotium rolfsii, has excellent water locking capacity and activity bioactivity by preventing cell water loss through a space for increasing the water content of cells, and the hexapeptide with excellent anti-aging, repairing and antioxidant effects has all functions of botulinum toxin without any toxicity, has similar effects of inhibiting nerve conduction substances, blocking the conduction function between nerve muscles, avoiding over-contraction of muscles and preventing fine wrinkles from forming.
In addition, active ingredients of a ginseng extract, a pine needle water extract, a honeysuckle flower extract and a centella extract are selected in the formula, wherein the ginseng extract contains volatile oil ginseng saponin, polysaccharide, various low molecular weight skin amino acids, B vitamins, vitamin C and the like, so that the blood circulation of the skin can be improved, the metabolism of the skin is promoted, and the effect of delaying skin aging is achieved; the pine needle water extract has the effects of dissolving ageing substances in a human body, adjusting and promoting body and tissue functions and promoting human health; the honeysuckle flower extract can improve the water retention capacity of skin and form a natural water-locking barrier; the centella asiatica extract has strong oxidation resistance, can inhibit free radical activity, lighten melanin pigmentation, improve skin blood circulation, renew skin cell regeneration, help melanin to be successfully metabolized out of the body, and has smooth and tender skin, whitening and brightening skin after being used. The four components are used together, can promote cell regeneration, increase skin elasticity, resist oxidation and remove oxygen free radicals, and has remarkable whitening, moisturizing and anti-wrinkle effects.
Detailed Description
For a better understanding and an enabling description of the present invention, reference will now be made to the following examples which are set forth in order to provide a further understanding of the invention.
The preparation process of the ginseng extract in each embodiment of the invention comprises the following steps: grinding Ginseng radix, pulverizing, decocting in 6 times of water for 3 hr, filtering, and concentrating the filtrate to obtain concentrated solution with relative density of 1.05-1.10.
The preparation process of the pine needle water extract comprises the following steps: grinding and crushing pine needles, adding 6 times of water, decocting twice for 2 hours for the first time and 1 hour for the second time, filtering, combining filtrates, and concentrating to obtain a concentrated solution with the relative density of 1.05-1.10.
The preparation process of the honeysuckle flower extract comprises the following steps: grinding and crushing honeysuckle flower, adding 6 times of water, decocting twice, filtering for 2 hours for the first time and 1 hour for the second time, combining the filtrates, and concentrating to obtain a concentrated solution with the relative density of 1.05-1.10.
The preparation process of the centella extract comprises the following steps: grinding and crushing centella, adding 6 times of water, decocting twice, decocting for 2 hours for the first time and 1 hour for the second time, filtering, combining filtrates, and concentrating to obtain a concentrated solution with the relative density of 1.05-1.10.
Example 1
Weighing the following raw materials in parts by mass for later use:
crosslinked sodium hyaluronate 80KG, hydrolyzed sodium hyaluronate 6KG, ceramide II type 1.5KG, hydrolyzed sclerotinia sclerotiorum gum 2KG, glyceryl acrylate 1KG, hexapeptide 1.5KG, ginseng extract 5KG, pine needle water extract 1.8KG, honeysuckle flower extract 1.5KG, centella asiatica extract 2 KG.
The preparation method comprises the following steps:
s1: adding ceramide and glycerol acrylate into a stirring container, controlling the rotating speed at 100-300rmp at the temperature of 60-80 ℃, stirring for 10-20min until the ceramide is completely dissolved to form a uniform mixed solution, and then cooling to the normal temperature;
s2: adding the hydrolyzed sclerotium rolfsii and the hexapeptide into the mixed solution in the step S1, and continuing stirring for 5-10 min;
s3: adding cross-linked sodium hyaluronate and sodium hyaluronate into the mixed solution in the step S2, controlling the rotating speed at 100-200rmp, and uniformly mixing;
s4: adding the ginseng extract, the pine needle water extract, the honeysuckle flower extract and the centella asiatica extract into the mixed solution in the step S3, and slowly stirring until the mixture is uniformly mixed;
s5: sterilizing and filling.
Example 2
Weighing the following raw materials in parts by mass for later use:
85KG of cross-linked sodium hyaluronate, 8KG of hydrolyzed sodium hyaluronate, 0.5KG of ceramide II type, 3KG of hydrolyzed sclerotinia sclerotiorum gum, 3KG of glycerol acrylate, 0.5KG of hexapeptide, 5KG of ginseng extract, 1.8KG of pine needle water extract, 1.5KG of honeysuckle flower extract and 2KG of centella extract.
The preparation method of this example has the same process steps as example 1.
Example 3
Weighing the following raw materials in parts by mass for later use:
90KG of cross-linked sodium hyaluronate, 5KG of hydrolyzed sodium hyaluronate, 3KG of ceramide II type, 0.5KG of hydrolyzed sclerotinia sclerotiorum gum, 0.5KG of glycerol acrylate, 2KG of hexapeptide, 5KG of ginseng extract, 1.8KG of pine needle water extract, 1.5KG of honeysuckle flower extract and 2KG of centella extract.
The preparation method of this example has the same process steps as example 1.
The product of the invention was tested as follows:
100 testers with loose facial skin, more fine wrinkles and severe pigmentation are selected, the testers are aged between 30 and 50 years and randomly divided into four groups, after the skin is cleaned in the morning and evening, commercially available skin care products are respectively selected as the products prepared by the comparative examples and the formulas of the examples 1 to 3 to be matched with an introduction instrument for use, the products are used once in the morning and at night and are continuously used for 60 days, and the specific results are as follows:
and (4) result evaluation standard:
has obvious effects: the experimenter feels very satisfied with the self, the facial skin has more elasticity, compactness and smoothness, the skin is fine and smooth, the facial fine lines are obviously reduced, the skin color is obviously whitened, and the skin texture density under a microscope is obviously reduced.
Has little effect: the experimenter feels common, the elastic, glossy and smooth degree of the facial skin is slightly increased, the complexion is whitened, the fine lines of the face are reduced, and the texture density of the skin under a microscope is slightly reduced.
No effect is achieved: the experimenter feels dissatisfied with the self, the elastic, glossy and smooth degree of the facial skin is not increased, the fine lines of the face are not obviously improved, the density of the skin texture under a microscope is not improved, and the pigmentation of the epidermis is not improved.
The test effect is counted as follows:
| group of | Number of test persons | Has obvious effect | Has little effect | Without effect | Allergic reaction |
| Comparative example | 25 persons | 6 persons | 12 persons | 5 persons | 2 persons |
| Example 1 | 25 persons | 22 persons | 3 persons | 0 person | 0 person |
| Example 2 | 25 persons | 21 persons | 4 persons | 0 person | 0 person |
| Example 3 | 25 persons | 20 persons | 5 persons | 0 person | 0 person |
The experimental result shows that the product prepared by the beauty formula has the effects of obviously promoting skin metabolism, enhancing skin activity, reducing epidermal pigmentation, resisting oxidation and removing oxygen free radicals after being used for a long time, has obvious whitening, moisturizing and anti-wrinkle effects and does not have any side effect.
The present invention has been described in terms of specific examples, which are provided to aid understanding of the invention and are not intended to be limiting. For a person skilled in the art to which the invention pertains, several simple deductions, modifications or substitutions may be made according to the idea of the invention.
Claims (7)
1. The beauty formula is characterized by comprising the following raw materials in parts by mass:
80-90 parts of cross-linked sodium hyaluronate
5-8 parts of hydrolyzed sodium hyaluronate
0.5-3 parts of ceramide
0.5-3 parts of hydrolyzed sclerotium rolfsii gum
0.5-3 parts of glycerol acrylate
0.5-2 parts of hexapeptide.
2. The cosmetic formulation according to claim 1, comprising the following raw materials in parts by mass:
80 parts of crosslinked sodium hyaluronate
Hydrolyzed sodium hyaluronate 6 parts
Ceramide 1.5 parts
2 parts of hydrolyzed sclerotium rolfsii gum
1 part of glycerol acrylate
1.5 parts of hexapeptide.
3. The cosmetic formulation according to claim 2, further comprising a plant extract comprising 5 parts of ginseng extract, 1.8 parts of pine needle water extract, 1.5 parts of honeysuckle flower extract and 2 parts of centella asiatica extract.
4. The cosmetic formulation according to claim 3, wherein said ceramide is selected from ceramide type II.
5. The method of preparing a cosmetic formulation according to claim 4, comprising the steps of:
s1: firstly, stirring ceramide and glyceryl acrylate for 10-20min at the temperature of 60-80 ℃ until the ceramide is completely dissolved to form a uniform mixed solution, and then cooling to normal temperature;
s2: adding the hydrolyzed sclerotium rolfsii and the hexapeptide into the mixed solution in the step S1, and continuing stirring for 5-10 min;
s3: adding cross-linked sodium hyaluronate and sodium hyaluronate into the mixed solution in the step S2, and uniformly mixing;
s4: adding the ginseng extract, the pine needle water extract, the honeysuckle flower extract and the centella asiatica extract into the mixed solution in the step S3, and slowly stirring until the mixture is uniformly mixed;
s5: sterilizing and filling.
6. The method for preparing a cosmetic formulation according to claim 5, wherein the rotation speed during the stirring in steps S1 and S2 is 100-300 rmp.
7. The method for preparing a cosmetic formulation according to claim 5, wherein the rotation speed during the stirring process of step S3 is 100-200 rmp.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811524489.7A CN111317678A (en) | 2018-12-13 | 2018-12-13 | Beautifying formula |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811524489.7A CN111317678A (en) | 2018-12-13 | 2018-12-13 | Beautifying formula |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105686980A (en) * | 2014-11-24 | 2016-06-22 | 深圳鑫新阳光实业发展有限公司 | Essence capable of nourishing relieving and restoring eyes |
| CN106361592A (en) * | 2015-07-23 | 2017-02-01 | 强生消费者公司 | Topical delivery of skin compositions having low pH |
| CN107998437A (en) * | 2016-10-31 | 2018-05-08 | 常州药物研究所有限公司 | Nanometer cross-linking hyaluronic acid sodium gel and its preparation method and application |
| CN108420767A (en) * | 2018-05-15 | 2018-08-21 | 上海东晟源日化有限公司 | It is a kind of that there are the crease-resistant skin care item to compact with U.S. face moisture-keeping efficacy |
| CN108478464A (en) * | 2018-04-29 | 2018-09-04 | 广州丽彦妆生物科技有限公司 | A kind of skin makeup peptide facial mask liquid and preparation method thereof |
-
2018
- 2018-12-13 CN CN201811524489.7A patent/CN111317678A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105686980A (en) * | 2014-11-24 | 2016-06-22 | 深圳鑫新阳光实业发展有限公司 | Essence capable of nourishing relieving and restoring eyes |
| CN106361592A (en) * | 2015-07-23 | 2017-02-01 | 强生消费者公司 | Topical delivery of skin compositions having low pH |
| CN107998437A (en) * | 2016-10-31 | 2018-05-08 | 常州药物研究所有限公司 | Nanometer cross-linking hyaluronic acid sodium gel and its preparation method and application |
| CN108478464A (en) * | 2018-04-29 | 2018-09-04 | 广州丽彦妆生物科技有限公司 | A kind of skin makeup peptide facial mask liquid and preparation method thereof |
| CN108420767A (en) * | 2018-05-15 | 2018-08-21 | 上海东晟源日化有限公司 | It is a kind of that there are the crease-resistant skin care item to compact with U.S. face moisture-keeping efficacy |
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Application publication date: 20200623 |