CN110973410A - Formula and preparation method of in-vivo and in-vitro antidote for aquatic animals - Google Patents

Formula and preparation method of in-vivo and in-vitro antidote for aquatic animals Download PDF

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Publication number
CN110973410A
CN110973410A CN201911385965.6A CN201911385965A CN110973410A CN 110973410 A CN110973410 A CN 110973410A CN 201911385965 A CN201911385965 A CN 201911385965A CN 110973410 A CN110973410 A CN 110973410A
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CN
China
Prior art keywords
antidote
vivo
vitro
mixing
preparation
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Pending
Application number
CN201911385965.6A
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Chinese (zh)
Inventor
谢维宣
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Hainan Chief Biology Technique Empolder Co ltd
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Hainan Chief Biology Technique Empolder Co ltd
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Priority to CN201911385965.6A priority Critical patent/CN110973410A/en
Publication of CN110973410A publication Critical patent/CN110973410A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/80Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins

Abstract

The invention discloses a formulation and a preparation method of an in vivo and in vitro antidote for aquatic animals. The invention can prevent various vitamins and trace elements from being lack, promote growth and development and improve the absorption and utilization of feed; participating in the generation of red blood cells and hemoglobin, promoting the generation of immunoglobulin and enhancing the utilization of glutamic acid; complexing and degrading algae toxins, bacteria toxins, ammonia nitrogen, hydrogen sulfide, nitrite, heavy metals, antibiotics, pesticide residues and other toxins, protecting the liver and promoting healthy growth; cooling, anti-stress, eliminating bottom heat, relieving and eliminating anaerobic fermentation; eliminating various strong stress reactions caused by water quality deterioration, hot weather, pond passing, catching, rainy days, low-temperature days, day and night temperature difference and the like.

Description

Formula and preparation method of in-vivo and in-vitro antidote for aquatic animals
Technical Field
The invention relates to the technical field of antidotes, in particular to a formula of an in-vivo and in-vitro antidote for aquatic animals and a preparation method thereof.
Background
Aquatic products occupy an important position in national dietary structure, can provide high-quality protein food for human beings, develop the aquaculture industry of aquatic animals, improve national food structure and quality of life of people, improve national nutrition and health level, and have positive effects on realizing good health and long life.
The applicant of the present invention finds that in the process of aquatic product cultivation, antibiotics and various antiviral medicines are added into a pond or a reservoir in order to prevent aquatic animals from getting ill, and because the living space of the cultivated aquatic animals is relatively small, the antibiotics and medicines in the aquatic animals are not discharged out of the bodies of the aquatic animals when the aquatic animals are sold, which can seriously affect the quality of the aquatic animals.
Disclosure of Invention
The invention aims to provide a formula and a preparation method of an in-vivo and in-vitro antidote for aquatic animals, and aims to solve the problem that the aquatic animals contain heavy metals, antibiotics, pesticide residues and heavy metals.
The invention is realized by the following steps:
a formulation of an in vivo and in vitro antidote for aquatic animals and its preparation method comprises pulverizing and screening raw materials and adjuvants, weighing trace raw materials, mixing and stirring at first stage, weighing vitamins, and mixing and stirring at second stage.
Further, the process of crushing the raw and auxiliary materials comprises the following steps: mixing Glycyrrhrizae radix and herba Menthae at a ratio of 1: 1, pulverizing with pulverizer, and screening to obtain material A.
Further, the process of weighing the trace raw materials comprises the following steps: ferrous sulfate and copper sulfate are weighed by an analytical balance, and the ferrous sulfate and the copper sulfate are mixed according to the proportion of 1: 0.15 to obtain a material B.
Further, the primary mixing and stirring process comprises the following steps: mixing the material A and the material B according to the proportion of 1: 0.13 to obtain a material C.
Further, the aquatic animal in-vivo and in-vitro antidote formula and the preparation method thereof according to claim 4 are characterized in that the vitamin weighing process comprises the following steps: and weighing the vitamin B2 and the folic acid by using an analytical balance, and mixing the vitamin B2 and the folic acid according to the ratio of 1: 1 to obtain a material D.
Further, the secondary mixing and stirring process comprises the following steps: and mixing the material C and the material D according to the ratio of 1: 0.0017 to obtain a finished antidote product.
Compared with the prior art, the invention has the beneficial effects that: the invention can prevent various vitamins and trace elements from being lack, promote growth and development and improve the absorption and utilization of feed; participating in the generation of red blood cells and hemoglobin, promoting the generation of immunoglobulin and enhancing the utilization of glutamic acid; complexing and degrading algae toxins, bacteria toxins, ammonia nitrogen, hydrogen sulfide, nitrite, heavy metals, antibiotics, pesticide residues and other toxins, protecting the liver and promoting healthy growth; cooling, anti-stress, eliminating bottom heat, relieving and eliminating anaerobic fermentation; eliminating various strong stress reactions caused by water quality deterioration, hot weather, pond passing, catching, rainy days, low-temperature days, day and night temperature difference and the like.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the embodiments of the present invention will be described clearly and completely in conjunction with the description of the embodiments of the present invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention. Thus, the following detailed description of the embodiments of the present invention provided in the description is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
A formulation of an in vivo and in vitro antidote for aquatic animals and its preparation method comprises pulverizing and screening raw materials and adjuvants, weighing trace raw materials, mixing and stirring at first stage, weighing vitamins, and mixing and stirring at second stage.
The process of crushing the raw materials and the auxiliary materials comprises the following steps: mixing Glycyrrhrizae radix and herba Menthae at a ratio of 1: 1, pulverizing with pulverizer, and screening to obtain material A.
The process of weighing the trace raw materials comprises the following steps: ferrous sulfate and copper sulfate are weighed by an analytical balance, and the ferrous sulfate and the copper sulfate are mixed according to the proportion of 1: 0.15 to obtain a material B.
The first-stage mixing and stirring process comprises the following steps: mixing the material A and the material B according to the proportion of 1: 0.13 to obtain a material C.
The process of vitamin weighing comprises the following steps: and weighing the vitamin B2 and the folic acid by using an analytical balance, and mixing the vitamin B2 and the folic acid according to the ratio of 1: 1 to obtain a material D.
The secondary mixing and stirring process comprises the following steps: and mixing the material C and the material D according to the ratio of 1: 0.0017 to obtain a finished antidote product.
The effects of the raw materials are as follows:
licorice root: eliminating various strong stress reactions caused by water quality deterioration, hot weather, pond passing, catching, rainy days, low-temperature days, day and night temperature difference and the like;
mint: cooling, anti-stress, eliminating bottom heat, relieving and eliminating anaerobic fermentation;
ferrous sulfate: complexing and degrading algae toxins, bacteria toxins, ammonia nitrogen, hydrogen sulfide, nitrite, heavy metals, antibiotics, pesticide residues and other toxins, protecting the liver and promoting healthy growth;
copper sulfate: copper sulfate has strong capability of killing pathogens, can be used for preventing and treating fish diseases caused by algae, such as adhesion disease of starch egg and green mud moss, and also can prevent diseases caused by protozoa, such as cryptotrichinemia, ciliate and Chinese harassment;
vitamin B2: it is also known as riboflavin (which has a chemical name because it contains ribose and isoalloxazine in its structure and is yellow). B2 is slightly soluble in water and alcohol, but insoluble in other organic solvents; the material is stable in an acid solution, but is easy to decompose in alkali liquor or when exposed to visible light; physiological function of vitamin B2: in vivo in the form of Flavin Mononucleotide (FMN) and Flavin Adenine Dinucleotide (FAD); FMN and FAD are coenzymes of many oxidoreductases in the body and play a role in hydrogen delivery in redox reactions. In addition, B2 has important effects on maintaining normal functions of skin, mucosa and vision, participating in the production of erythrocyte and hemoglobin, promoting the production of immunoglobulin, and enhancing the utilization of glutamic acid;
folic acid: acid, also known as an anti-anemia factor, is a yellow crystal, slightly soluble in water, stable in acidic solutions, but readily decomposed by heat or light. Physiological function of folic acid: in vivo, the folic acid reductase catalyzes and hydrogenates the folic acid into tetrahydrofolic acid (THFA), the THFA is a coenzyme of the body-carbon group (such as-CH 3, -CH2OH and-CH 2-) transferase, and the transfer of the-carbon group is closely related to the synthesis of purine and pyrimidine and the metabolism of amino acid.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (6)

1. An aquatic animal in-vivo and in-vitro antidote formula and a preparation method thereof are characterized in that: crushing and screening raw materials and auxiliary materials, weighing trace raw materials, mixing and stirring at a first stage, weighing vitamins and mixing and stirring at a second stage.
2. The aquatic animal in-vivo and in-vitro antidote formula and the preparation method according to claim 1, wherein the raw and auxiliary materials are crushed by the following steps: mixing Glycyrrhrizae radix and herba Menthae at a ratio of 1: 1, pulverizing with pulverizer, and screening to obtain material A.
3. The aquatic animal in-vivo and in-vitro antidote formula and the preparation method according to claim 2, wherein the process of weighing the trace raw materials comprises the following steps: ferrous sulfate and copper sulfate are weighed by an analytical balance, and the ferrous sulfate and the copper sulfate are mixed according to the proportion of 1: 0.15 to obtain a material B.
4. The aquatic animal in-vivo and in-vitro antidote formula and the preparation method according to claim 3, wherein the primary mixing and stirring process comprises the following steps: mixing the material A and the material B according to the proportion of 1: 0.13 to obtain a material C.
5. The aquatic animal in-vivo and in-vitro antidote formula and the preparation method according to claim 4, wherein the vitamin weighing process comprises the following steps: and weighing the vitamin B2 and the folic acid by using an analytical balance, and mixing the vitamin B2 and the folic acid according to the ratio of 1: 1 to obtain a material D.
6. The aquatic animal in-vivo and in-vitro antidote formula and the preparation method according to claim 5, wherein the secondary mixing and stirring process comprises the following steps: and mixing the material C and the material D according to the ratio of 1: 0.0017 to obtain a finished antidote product.
CN201911385965.6A 2019-12-29 2019-12-29 Formula and preparation method of in-vivo and in-vitro antidote for aquatic animals Pending CN110973410A (en)

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CN201911385965.6A CN110973410A (en) 2019-12-29 2019-12-29 Formula and preparation method of in-vivo and in-vitro antidote for aquatic animals

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CN201911385965.6A CN110973410A (en) 2019-12-29 2019-12-29 Formula and preparation method of in-vivo and in-vitro antidote for aquatic animals

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CN110973410A true CN110973410A (en) 2020-04-10

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CN101040669A (en) * 2007-04-19 2007-09-26 广东恒兴集团有限公司 Formulation and preparing method of expanded assorted feed for micropterus salmoides
US20080188427A1 (en) * 2005-05-26 2008-08-07 Clayton Paul Dick Fish Production
CN101647524A (en) * 2009-08-14 2010-02-17 淮安华威饲料发展有限公司 Feed for controlling medicine residues of channel catfishes
CN104206805A (en) * 2014-07-22 2014-12-17 众合发(北京)生物科技发展有限公司 Preparation for degrading vivotoxin and enhancing anti-stress capability of aquatic animals
CN106798192A (en) * 2016-12-12 2017-06-06 新昌县柏克动物饲料技术开发有限公司 Prevent the Chinese herbal feed additive of shrimp crab crust canker
CN106852396A (en) * 2015-12-08 2017-06-16 上海泓宝绿色水产股份有限公司 A kind of aquatic livestock liver-care preparations and its preparation and application
CN107712273A (en) * 2017-11-07 2018-02-23 熊国顺 Improve feed of bream anti-stress ability and preparation method thereof
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US20080188427A1 (en) * 2005-05-26 2008-08-07 Clayton Paul Dick Fish Production
CN101040669A (en) * 2007-04-19 2007-09-26 广东恒兴集团有限公司 Formulation and preparing method of expanded assorted feed for micropterus salmoides
CN101647524A (en) * 2009-08-14 2010-02-17 淮安华威饲料发展有限公司 Feed for controlling medicine residues of channel catfishes
CN104206805A (en) * 2014-07-22 2014-12-17 众合发(北京)生物科技发展有限公司 Preparation for degrading vivotoxin and enhancing anti-stress capability of aquatic animals
CN106852396A (en) * 2015-12-08 2017-06-16 上海泓宝绿色水产股份有限公司 A kind of aquatic livestock liver-care preparations and its preparation and application
US20190021368A1 (en) * 2016-01-22 2019-01-24 Guangzhou Insighter Biotechnology Co.,Ltd. Use of copper-calcium sulphate as animal feed additive
CN106798192A (en) * 2016-12-12 2017-06-06 新昌县柏克动物饲料技术开发有限公司 Prevent the Chinese herbal feed additive of shrimp crab crust canker
CN107712273A (en) * 2017-11-07 2018-02-23 熊国顺 Improve feed of bream anti-stress ability and preparation method thereof
CN110558436A (en) * 2019-08-22 2019-12-13 英联普美欣科技(江西)有限公司 Ruminant anti-stress premixed feed, preparation method and application

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