CN110934804A - Skin micro-ecological nursing mask added with distiller's grains - Google Patents
Skin micro-ecological nursing mask added with distiller's grains Download PDFInfo
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- CN110934804A CN110934804A CN201911372045.0A CN201911372045A CN110934804A CN 110934804 A CN110934804 A CN 110934804A CN 201911372045 A CN201911372045 A CN 201911372045A CN 110934804 A CN110934804 A CN 110934804A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Abstract
The invention discloses a skin micro-ecological nursing facial mask added with distiller's grains, which comprises rice (ORYZA SATIVA) lees extract/molasses, saccharomycetes/rice fermentation filtrate, lactobacillus/mung bean (PHASEOLUS RADIATUS) seed extract/sodium glutamate fermentation product filtrate, fructooligosaccharide, β -glucan, corn gluten amino acids and auxiliary components.
Description
Technical Field
The invention relates to the field of daily chemicals, and particularly relates to a skin micro-ecological nursing facial mask added with distiller's grains.
Background
A large number of microorganisms exist on the surface of human skin, and about 200-300 bacteria exist. The type and amount of microorganisms in the skin have a very important influence on the health of the skin. For example, abnormally large increases in acne bacilli in the skin can lead to skin acne problems; an increased imbalance of malassezia in the scalp leads to the production of dandruff. The good skin microbial balance can form a protective layer for the skin. Help skin maintain good pH value; prevent the invasion and breeding of harmful bacteria; enhancing the immune system of the skin; participate in the synthesis of nutrition, etc. Along with the change of life style and living environment, people with skin microbial imbalance are more and more, and the skin problems caused by the people are more and more serious. However, most of cosmetics in the market still stay in common traditional means of cleaning, moisturizing and the like, and the important influence of microorganisms on the surface of the skin on the health of the skin is ignored. And thus, a plurality of skin problems are not scientifically and reasonably nursed.
Disclosure of Invention
The invention relates to a skin micro-ecological nursing facial mask added with distiller's grains, which can improve the problem of skin microorganisms, and can effectively balance the population and the quantity of the skin microorganisms so as to return the skin to a healthy state.
In order to realize the functions, the invention provides the following technical scheme:
the skin micro-ecological nursing facial mask added with the alcohol dregs comprises, by weight, 0.5-8% of rice (Oryza SATIVA) lees extract/molasses, 1-8% of yeast/rice fermentation filtrate, 0.1-0.5% of lactobacillus/mung bean (Phaseolus radiatus) seed extract/sodium glutamate fermentation product filtrate, 0.5-2% of fructo-oligosaccharide, 0.2-1.5% of β -glucan, 0.5-1% of corn gluten amino acids, 0.1-0.3% of allantoin, 0.5-2% of betaine, 5-30% of glycerol, 1-5% of 1, 3-propylene glycol and 45.9-90.6% of auxiliary components, wherein the auxiliary components comprise water, grease, emulsifier, preservative, solubilizer, thickener and humectant.
Preferably, the mask comprises, by weight, 0.5% of rice (Oryza SATIVA) lees extract/molasses, 2% of yeast/rice fermentation filtrate, 0.1% of lactobacillus/mung bean (Phaseolus RADIATUS) seed extract/sodium glutamate fermentation product filtrate, 0.5% of fructo-oligosaccharide, 0.2% of β -glucan, 0.5% of corn gluten amino acids, 0.1% of allantoin, 0.5% of betaine, 5% of glycerol, 2% of 1, 3-propanediol and 88.6% of auxiliary components.
Preferably, the yeast/rice fermentation filtrate is prepared by fermenting yeast in yellow wine and Wuchang rice.
The method for preparing the skin micro-ecological nursing mask added with the distiller's grains comprises the following steps: sequentially adding the components one by one, stirring and mixing, adding one component each time, stirring, mixing fully and completely dissolving, adding the next raw material, and stirring to be completely transparent and uniform after adding to obtain the skin micro-ecological nursing facial mask added with the distiller's grains.
Preferably, the method for preparing the skin micro-ecological nursing mask added with the alcohol dregs comprises the following steps of 1) mixing rice (Oryza SATIVA) lees extract/molasses with yeast/rice fermentation filtrate and water, stirring for 10 minutes to obtain a mixture, 2) sequentially adding fructo oligosaccharide, β -glucan, corn gluten amino acids, allantoin, betaine, glycerol, propylene glycol and residual auxiliary components except water into the mixture obtained in the step 1), stirring and mixing for full dissolution, adding the next raw material, and stirring to be completely transparent and uniform after the addition is finished to obtain the skin micro-ecological nursing mask added with the alcohol dregs.
The standard Chinese name of the distiller's grains extract in the invention is: the rice (ORYZA SATIVA) lees extract/molasses (without CAS number for a moment) is prepared by fermenting rice through yeast, has a long history as a product of traditional brewing, can provide a proper growth environment and nutrient components required by metabolism for beneficial bacteria in skin, and enables the probiotics on the surface of the skin to return to normal growth, thereby competitively reducing the number and the types of pathogenic bacteria and harmful bacteria. The skin surface is in a healthy and stable environment. After the test subject uses the mask added with the distiller's grains extract for 4 weeks, the means of gene test shows that the types of microorganisms on the skin surface of the test subject are richer and the quantity of the microorganisms is more balanced than before. Three key bacteria respectively corresponding to oil secretion, skin moisturizing ability and skin barrier in the skin: the acne bacillus, corynebacterium coelicolor and staphylococcus epidermidis all return to more reasonable levels, and the physiological indexes of the skin are obviously improved.
The yeast/rice fermentation filtrate in the invention has standard Chinese name: the yeast/rice fermentation filtrate (without CAS number) is prepared by fermenting yeast in Shaoxing yellow wine and Wuchang rice, is rich in various micromolecule nutrients required by skin, is easy to be absorbed and utilized by skin, and has comprehensive nutrition, and is mild in nourishing and repairing skin.
The lactobacillus/mung bean (PHASEOLUS RADIATUS) seed extract/sodium glutamate fermentation product filtrate of the present invention, standard chinese name: lactobacillus/semen Phaseoli Radiati (Phaseolus RADIATUS) seed extract/sodium glutamate fermentation product filtrate (without CAS number) is obtained by fermenting semen Phaseoli Radiati and lactobacillus together, and has effects of improving skin resistance and relieving skin allergy symptom due to external stimulation.
The standard Chinese name of the fructo-oligosaccharide of the invention is: the fructo-oligosaccharide (no CAS number temporarily) is a plant source, has good moisturizing capability, is the nutrition of probiotic microorganisms on the surface of the skin, and enables the probiotic microorganisms in the skin to grow better.
The β -glucan of the invention has the standard Chinese name of β -glucan (CAS number: 160872-27-5; 53238-80-5; 55965-23-6), has the effect of improving the immunity of the skin, is the nutrition of probiotic microorganisms on the surface of the skin and enables the probiotic microorganisms in the skin to grow better.
The corn gluten amino acids in the invention have standard Chinese names: corn gluten amino acids (CAS number: 65072-01-7) extracted from corn has good moisturizing and repairing effects.
Allantoin in the present invention, standard chinese name: allantoin (CAS number: 97-59-6), as a traditional ingredient in the medical field, is used to repair soft skin, improve cell renewal, and promote wound healing.
Betaine in the invention, standard Chinese name: betaine (CAS number: 107-43-7) is extracted from beet, and NMF in skin mainly contains the components for supplementing natural skin moisturizing factors, and moisturizing, moistening and brightening skin.
Glycerol in the present invention, standard chinese name: glycerol (CAS number: 56-81-5), a plant source, is one of moisturizing care ingredients with the highest cost performance, and has good moisturizing effect.
1, 3-propanediol in the invention, standard Chinese name: 1, 3-propylene glycol (CAS number: 504-63-2; 26264-14-2), has good moisturizing effect, and can greatly improve the original moisturizing capability of glycerin when being compounded with glycerin according to a specific proportion.
The distiller's grains applied to the mask are obtained by fermenting yeast, and have a long history as a product of traditional wine brewing. However, its role in cosmetics has been in a blank state. Tests show that the product fermented by the yeast and the grains can provide a proper growth environment and nutrient components required by metabolism for beneficial bacteria in the skin, and the beneficial bacteria on the surface of the skin return to normal growth, so that the quantity and the types of pathogenic bacteria and harmful bacteria are reduced competitively. The skin surface is in a healthy and stable environment. After the test subject uses the mask added with the distiller's grains extract for 4 weeks, the means of gene test shows that the types of microorganisms on the skin surface of the test subject are richer and the quantity of the microorganisms is more balanced than before. Three key bacteria respectively corresponding to oil secretion, skin moisturizing ability and skin barrier in the skin: acne, corynebacterium coelicolor and staphylococcus epidermidis all have corresponding improvements.
The wine cake mask completely meets all indexes in the cosmetic hygiene standard (2015 edition) issued by the state, and the composition does not contain any toxic substance.
The distiller's grains mask is a cream-shaped product, can be directly smeared on the surface of skin, and is washed clean after being applied for 15-30 minutes. Mainly for the face and neck.
Has the advantages that:
the distiller's grains facial mask provided by the invention is based on skin microbiology, can improve the problem of skin microorganisms, and can effectively balance the population and the quantity of the skin microorganisms, so that the skin returns to a healthy state.
Detailed Description
The invention is further illustrated with reference to the following examples:
the specific proportions of the distiller's grains facial mask of examples 1-5 and comparative examples 1-3 of the invention are shown in Table 1
TABLE 1
The auxiliary components comprise water, grease, an emulsifier, a preservative, a solubilizer, a thickener, a humectant, water and the like, almost have no influence on the efficacy of the product, and are prepared according to the conventional national standard.
The method for preparing the distiller's grains mask of examples 1-5 and comparative examples 1-3 includes the steps of 1) mixing rice (oryza sativa) lees extract/molasses with yeast/rice fermentation filtrate and water, stirring for 10 minutes to obtain a mixture, 2) adding fructooligosaccharide, β -dextran, corn gluten amino acids, allantoin, betaine, glycerin, propylene glycol and the remaining auxiliary components except water to the mixture obtained in step 1) in sequence, stirring each component, mixing completely and dissolving completely, adding the next raw material, and stirring to be completely transparent and uniform after adding to obtain the distiller's grains-added skin micro-ecological nursing mask.
Example 6
Example 6 differs from example 1 only in that the auxiliary ingredient was mixed with glycerin, and other preparation methods and preparation conditions were the same as those of example 1.
Comparative example 4
Comparative example 4 differs from example 1 only in that no rice (ORYZA SATIVA) spent grain extract/molasses is added and other preparation methods and preparation conditions are identical to those of example 1.
Comparative example 5
Comparative example 5 is different from example 1 only in that yeast/rice fermentation filtrate was not added, and other preparation methods and preparation conditions were identical to those of example 1.
Comparative example 6
Comparative example 6 differs from example 1 only in that lactobacillus/mung bean (PHASEOLUS RADIATUS) seed extract/sodium glutamate fermentation product filtrate was not added, and other preparation methods and preparation conditions were identical to those of example 1.
The lees mask products prepared in examples 1 to 6 and comparative examples 1 to 6 were subjected to tests such as microbial population change and skin physiological parameter change. The change of microbial population mainly monitors three common skin floras of acne bacillus (excessive harmful strains), corynebacterium (proper amount of beneficial strains) and staphylococcus (excessive harmful strains), and the corresponding skin physiological indexes are skin grease secretion, skin percutaneous water loss and skin redness.
The clinical experimental conditions were: 120 women, 10 in each group, aged 20-45, were used 1 time every 2 days for 28 consecutive days, and the average data for each group were recorded, and the experimental results are shown in tables 2 and 3.
Table 2 (microbial count variation):
table 3 (skin physiological index change):
as can be seen from tables 2 and 3, example 1 is the best option, and from comparison of example 6 with example 1, it is better to mix rice (Oryza SATIVA) grain extract/molasses with yeast/rice fermentation filtrate and water, and then add other components, as seen from comparison of comparative examples 4-6 with example 1, the rice (Oryza SATIVA) grain extract/molasses, yeast/rice fermentation filtrate and lactobacillus/mung bean (Lactobacillus RADIATUS) seed extract/sodium glutamate fermentation product filtrate of the present invention synergize synergistically to balance the population and amount of skin microorganisms, thereby allowing the skin to return to a healthy state, and any one of the lack of rice (Oryza SATIVA) grain extract/molasses, yeast/rice fermentation filtrate and lactobacillus/mung bean (Lactobacillus raduatus) seed extract/sodium glutamate fermentation product filtrate can greatly affect the change in the amount of skin surface microorganisms, as can be seen from comparison of comparative examples 1-3 with example 1, the skin micro-ecological care mask of the distiller's grains of the present invention has an excellent effect of balancing the population and amount of skin microorganisms to return the skin to a healthy state only when the rice (Oryza SATIVA) grain extract/molasses is 0.5-8%, yeast/rice fermented filtrate is 1-8%, and lactobacillus/mung bean (Phaseolus RADIATUS) seed extract/sodium glutamate fermented product filtrate is 0.1-0.5%.
Claims (5)
1. A skin micro-ecological nursing facial mask added with alcohol dregs is characterized by comprising, by weight, 0.5-8% of rice (ORYZA SATIVA) lees extract/molasses, 1-8% of yeast/rice fermentation filtrate, 0.1-0.5% of lactobacillus/mung bean (PHASEOLUS RADIATUS) seed extract/sodium glutamate fermentation product filtrate, 0.5-2% of fructo-oligosaccharide, 0.2-1.5% of β -glucan, 0.5-1% of corn gluten amino acids, 0.1-0.3% of allantoin, 0.5-2% of betaine, 5-30% of glycerol, 1-5% of 1, 3-propylene glycol and 45.9-90.6% of auxiliary components, wherein the auxiliary components comprise water, grease, an emulsifier, a preservative, a solubilizer, a thickener and a humectant.
2. The distiller's grains-added skin micro-ecological nursing mask as set forth in claim 1, wherein the mask comprises, by weight, 0.5% of rice (Oryza SATIVA) grains extract/molasses, 2% of yeast/rice fermentation filtrate, 0.1% of lactobacillus/mung bean (Phaseolus RADIATUS) seeds extract/sodium glutamate fermentation product filtrate, 0.5% of fructo-oligosaccharide, 0.2% of β -glucan, 0.5% of corn gluten amino acids, 0.1% of allantoin, 0.5% of betaine, 5% of glycerin, 2% of 1, 3-propylene glycol, and 88.6% of auxiliary ingredients.
3. The skin micro-ecological caring mask with added distiller's grains according to claim 1, wherein the yeast/rice fermentation filtrate is prepared by fermenting yeast in yellow wine and Wuchang rice.
4. A method of preparing the distiller's grains-supplemented skin micro-ecological care mask of any one of claims 1-3, comprising the steps of: sequentially adding the components one by one, stirring and mixing, adding one component each time, stirring, mixing fully and completely dissolving, adding the next raw material, and stirring to be completely transparent and uniform after adding to obtain the skin micro-ecological nursing facial mask added with the distiller's grains.
5. The method for preparing a mask for skin micro-ecological care containing distiller's grains according to claim 4, comprising the steps of 1) mixing rice (ORYZA SATIVA) lees extract/molasses with yeast/rice fermentation filtrate and water, and stirring for 10 minutes to obtain a mixture, 2) adding fructo-oligosaccharide, β -glucan, corn gluten amino acids, allantoin, betaine, glycerin, propylene glycol and the rest of auxiliary ingredients except water to the mixture obtained in step 1), sequentially stirring, mixing and dissolving completely, adding the next material, and stirring to be completely transparent and uniform after adding the next material to obtain the mask for skin micro-ecological care containing distiller's grains.
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| CN112826788A (en) * | 2021-01-26 | 2021-05-25 | 山东福瑞达生物工程有限公司 | Composition beneficial to skin micro-ecology after staying up all night, preparation method and application |
| CN113425657A (en) * | 2021-07-29 | 2021-09-24 | 广东丸美生物技术股份有限公司 | Moisturizing, anti-aging and whitening skin-care matrix and preparation method and application thereof |
| CN113425661A (en) * | 2021-08-11 | 2021-09-24 | 广州睿森生物科技有限公司 | Plant composition with cleaning and repairing effects and application thereof |
| CN115844772A (en) * | 2022-12-08 | 2023-03-28 | 贵州中心酿酒集团有限公司 | Distiller's grains mask and preparation method thereof |
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| CN112402356A (en) * | 2020-11-25 | 2021-02-26 | 周建大 | Pure micro-ecological skin cooling and nursing mask containing Chinese herbal medicines |
| CN112826788A (en) * | 2021-01-26 | 2021-05-25 | 山东福瑞达生物工程有限公司 | Composition beneficial to skin micro-ecology after staying up all night, preparation method and application |
| CN113425657A (en) * | 2021-07-29 | 2021-09-24 | 广东丸美生物技术股份有限公司 | Moisturizing, anti-aging and whitening skin-care matrix and preparation method and application thereof |
| CN113425661A (en) * | 2021-08-11 | 2021-09-24 | 广州睿森生物科技有限公司 | Plant composition with cleaning and repairing effects and application thereof |
| CN115844772A (en) * | 2022-12-08 | 2023-03-28 | 贵州中心酿酒集团有限公司 | Distiller's grains mask and preparation method thereof |
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