CN103110057A - Two-step fermentation preparation method and application of sweet fermented-rice nutrient or brewing nutrition products - Google Patents
Two-step fermentation preparation method and application of sweet fermented-rice nutrient or brewing nutrition products Download PDFInfo
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- CN103110057A CN103110057A CN2012104088046A CN201210408804A CN103110057A CN 103110057 A CN103110057 A CN 103110057A CN 2012104088046 A CN2012104088046 A CN 2012104088046A CN 201210408804 A CN201210408804 A CN 201210408804A CN 103110057 A CN103110057 A CN 103110057A
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- glutinous rice
- fermented glutinous
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- nutrients
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Abstract
The invention relates to a two-step fermentation preparation method and application of sweet fermented-rice nutrient or brewing nutrition products with extremely high values. The two-step fermentation preparation method comprises the following steps of: (1) fermenting raw materials to prepare initial sweet fermented-rice or fermenting products according to a sweet fermented-rice preparation process or a conventional brewing process; and (2) performing drying fermentation or drying during fermentation on the initial sweet fermented-rice or the initial brewing fermentation products in a low-temperature mode, or performing drying fermentation on the initial sweet fermented-rice or the initial brewing fermentation products for a certain time to directly prepare a nutrient solution on the basis of the step (1). The main nutritive components of the powder or substance are obviously higher than those of sweet fermented-rice prepared by a traditional method by 3-5 times, the total protein of the powder is close to 30 percent, and the content of essential amino acids of a human body is over 20 percent; and moreover, the product does not contain alcohol and can be naturally preserved for over 12 months. The product has the effects of resisting fatigue, enhancing immunity, improving sleep quality, improving sexual function, and promoting growth of white blood cells and development of infants. The product can be prepared into foods, health-care foods and medicines of various dosage forms by traditional methods and also can serve as ingredients of foods, health-care foods and medicines.
Description
Technical field
This patent of invention relates to a kind of high fermented glutinous rice nutrients or wine brewing nutritional product of being worth, i.e. product of a kind of fermented glutinous rice nutrients or the preparation of wine brewing nutritional product two-step fermenting and uses thereof.This thing can not add any anticorrisive agent and naturally preserve more than 12 months.This thing is except the food that is prepared into various formulations with traditional method, nutrient candy, health food, auxiliary curing medicine and treatment medicine.Also use as food, health food, auxiliary curing medicine and treatment medicine batching, also can be prepared into health products and medicine with other food materials and medicinal material prescription with health care and treatment function.
Background technology
Wine brewing is to utilize microbial fermentation production to contain the process of finite concentration alcoholic beverage.Liquor-making raw material and wine brewing container are two prerequisites of cereal wine brewing.Show according to the wine brewing utensil of Unearthed when Archaeological Studies apart from modern more than 5,000 year: there are this industry of making wine in legendary Yellow Emperor, a legendary ruler period, Yu's epoch summer, and the origin of wine brewing also before this.During time immemorial, people may first touch some natural fermented wine, are then copied.Domestic scholars generally believes, Longshan culture wine brewing in period is comparatively flourishing industry.Liquor-making raw material is different, and microorganism used therefor and brewing process are also different.The distiller's yeast wine brewing is the elite place of China's wine brewing.To modern age, modern times, the technology of wine brewing develops rapidly, adopts different raw materials and the technology of distiller's yeast to develop rapidly.Generally speaking, the core procedure of wine brewing is to select to ferment after raw material and distiller's yeast.
Fermented glutinous rice or be rice wine, have another name called fermented glutinour rice, ancients are " sweet wine ", are also a kind of wine brewing products.Also can say, fermented glutinous rice is that a kind of ethanol content that produces in the wine brewing process is few, the product that pol is higher, flavor is sweet.The fermented glutinous rice primary raw material is glutinous rice (glutinous rice), so also be glutinous rice wine or be glutinous rice wine.Fermented glutinous rice claims generally that in the north it is " rice wine " or " sweet wine ", is made by distiller's yeast (mainly comprise rhizopus etc. have fermentation, saccharification, benefit the bacterium of one or more functions such as give birth to and form).The loose soup of fermented glutinous rice rice is clear, and honey is aromatic strongly fragrant, and entrance is sweet, contains abundant multivitamin, glucose, the nutritional labelings such as amino acid can be whetted the appetite after drink and refresh oneself, and be had lively atmosphere to nourish blood, the function of enriching yin and nourishing kidney, puerpera and gynecologic menstrual are eaten more, and be outstanding helpful, is all suitable nutrient excellent product and tonics of old children.But the technology of brewageing fermented glutinous rice is wayward, grasps bad or yeast-bitten as time and temperature, the easy ageing of fermented glutinous rice, alcohol content increases or acidity increases, do not drink or people that capacity for liquor is not all right easily drunk or do not like drinking.The fermented glutinous rice moisture content is more than 50%, except carrying inconvenience, also is not easy to preserve perishable, must put into low temperature and store.As high-temperature sterilization or surpass 60 ℃, the active ingredients such as some active materials (as organized enzyme and phthaleins material etc.) are easily destroyed.The fermented glutinous rice of prior art has good nutritive value, for example has a sweet taste, and can be used for making numerous food or condiment for cooking.
In the wine brewing process, through the product that fermentation obtains, comprise that above-mentioned fermented glutinous rice all contains abundant nutrition.Yet the inventor is through studying discovery for a long period of time, and the nutritive value of fermented glutinous rice or wine brewing product is far from reaching and takes full advantage of.Particularly, after the fermentation step of fermented glutinous rice or wine brewing is complete, and after fermented glutinous rice finally made finished product such as fermented glutinour rice, the nutritional labeling of front and back altered a great deal, and the effect of its use is poor far especially.Further research is found, even the fermentation of the fermented glutinous rice of prior art complete after, must be through the high temperature operations such as enzyme and sterilizing of going out, otherwise fermented glutinous rice can continue fermentation, souring, last corruption.But, the high temperature enzyme process that goes out can cause organized enzyme, beneficial bacterium and peptide matters to decompose, and various nutriments and active principle comprise that useful enzyme and active material, microorganism etc. all can destroy, greatly lose nutriment, thereby cause fermented glutinous rice to lose itself beneficial effect and effect.And the sweat process of traditional wine brewing or fermented glutinous rice is single, as adopts solid-state nest fermentation or liquid state fermentation.All the time, above-mentioned tradition or conventional sweat all do not obtained larger breakthrough or improvement.
Purpose of the present invention is wanted to address the above problem topic thirty years of age exactly, and a kind of real, fermented glutinous rice of works very well or the product of wine brewing are provided.Because product of the present invention has nutritive value, be referred to as in the present invention fermented glutinous rice nutrients or wine brewing nutritional product.I have not only found this key technical problem, and by series of experiments, have solved preferably this technical problem, and new discovery and invention have been arranged.Therefore, purpose of the present invention be exactly to provide a kind of than common fermented glutinous rice nutritive value higher the fermented glutinous rice nutrients or the wine brewing nutritional product, and its production and use.It the results are shown in summary of the invention.
Summary of the invention
One, the invention provides a kind of fermented glutinous rice nutrients or wine brewing nutritional product, its main technical schemes is:
Technical scheme (one):
A kind of prepared fermented glutinous rice nutrient powder of fermented glutinous rice that is led to by glutinous rice or rice is characterized in that low temperature drying, and its dry temperature can not cause the beneficial bacterium in fermented glutinous rice to destroy.
Described fermented glutinous rice nutrient powder, the fermented glutinous rice that is led to by glutinous rice or rice is prepared into the fermented glutinous rice nutrient powder, it is characterized in that grasping dry temperature, and the temperature of described drying is 0-60 ℃, allows its drying.
Described fermented glutinous rice nutrient powder, the fermented glutinous rice that is led to by glutinous rice or rice is prepared into the fermented glutinous rice nutrient powder, it is characterized in that grasping dry temperature, and the temperature of described drying is 15-45 ℃, allows its drying.
Described fermented glutinous rice nutrient powder, this fermented glutinous rice nutrient powder can be used for being prepared into various forms of or adds various health foods, food, food additives, nutritious supplementary pharmaceutical, nutrient candy, fermented glutinous rice sugar, fermented glutinous rice beverage, biscuit, instant noodles, noodles to, and animal feed additive.
Described fermented glutinous rice nutrient powder, this powder can form composition with honey and be prepared into nutrient candy and food, as are made into fermented glutinous rice halavah, fermented glutinous rice honey cake and fermented glutinous rice honey paste (or congee).Its composite formula ratio is fermented glutinous rice nutrient powder 5.0-9.9 part: honey 0.1-5.0 part, especially formula rate is fermented glutinous rice nutrient powder 8-9.5 part: most suitable during honey 0.5-2 part.
Described fermented glutinous rice nutrient powder, this powder can with honey and sesame (or Semen sesami nigrum), be prepared into nutrient candy and health food with conventional method.As be made into fermented glutinous rice sesame seed candy, fermented glutinous rice honey cake, fermented glutinous rice honey mush (or congee).Its composite formula ratio is fermented glutinous rice nutrient powder 5.0-9.0 part: honey 0.5-3.0 part: sesame 0.5-2.0 part.Especially formula rate is at fermented glutinous rice nutrient powder 7.5-8.5 part: honey 0.5-1.5: most suitable during sesame 0.5-1.2 part.
Described fermented glutinous rice nutrient powder, this powder can form composition with honey and Poria cocos, is prepared into nutrient candy and health food with conventional method.As be made into fermented glutinous rice pachymose, fermented glutinous rice tuckahoe cake, fermented glutinous rice Poria cocos mush (or congee) and fermented glutinous rice Poria cocos biscuit.Its composite formula ratio is fermented glutinous rice nutrient powder 5.0-9.8 part: honey 0.1-2.0 part: Poria cocos 0.1-3.0 part.Especially formula rate is at fermented glutinous rice nutrient powder 7.5-9.0 part: honey 0.5-1.0: most suitable during Poria cocos 0.5-1.5 part.
Described fermented glutinous rice nutrient powder, this powder adds in food as a kind of nutrient additive for food, makes health food with conventional method.As fermented glutinous rice biscuit, the fragrant revive ball of fermented glutinous rice, fermented glutinous rice egg roll, fermented glutinous rice noodles, fermented glutinous rice instant noodles, milk fermented glutinous rice powder and lotus seeds fermented glutinous rice custard.The ratio that its powder adds is generally all comparatively suitable about 10-50%.
Be used for making various goods and preparation according to the above-mentioned fermented glutinous rice nutrient powder for preparing and composition, comprise powder, pill, granule, electuary, tablet, oral liquid and liquid beverage, and the preparation of pie shape, bar shaped and block shape, comprise relating to the traditional auxiliary material that adds in case of necessity.
Above-mentioned fermented glutinous rice nutrient powder or composition can add any one or multiple edible or medicinal animals and plants, Chinese medicine or animals and plants, Chinese medical extract.
Technical scheme (two):
1, a kind of fermented glutinous rice nutrients or wine brewing nutritional product, is characterized in that, adopts the two-step fermenting preparation, and its step is as follows:
(1) first step according to the common process of fermented glutinous rice preparation technology or wine brewing, prepares initial fermented glutinous rice or initial brewing fermentation product with fermenting raw materials;
(2) second step on the basis of step (1), adopts the mode of low temperature that initial fermented glutinous rice or initial brewing fermentation product are carried out drying or carries out the drying fermentation or drying in fermentation.
2, according to claim 1 the fermented glutinous rice nutrients or the wine brewing nutritional product, it is characterized in that, raw material described in step (1) is glutinous rice, rice, millet, wheat, corn, soybean, lotus seeds, coix seed, or arbitrary combination of above-mentioned raw materials or the combination of multiple thing, the particularly combination of glutinous rice and/or rice and other raw material different proportion;
Or in step (2), be in fermentation dried process or carry out drying fermentation or add powder when dry in fermentation, described powder is glutinous rice, rice, millet, wheat, corn, soybean, lotus seeds, coix seed, or arbitrary combination of above-mentioned raw materials or the combination of multiple thing, the particularly combination of glutinous rice and/or rice and other raw material different proportion.
3, according to claim 1 the fermented glutinous rice nutrients or the wine brewing nutritional product, it is characterized in that, the fermentation standard of the described initial fermented glutinous rice of the first step (1) or initial brewing fermentation product is: the initial fermented glutinous rice nest of A. can be seen the initial fermented glutinous rice of liquid or a little liquid or B. liquid can occur through slight extruding, or the initial fermented glutinous rice of C. has sweet taste or sweet taste slightly through trial test.
4, according to claim 1 the fermented glutinous rice nutrients or the wine brewing nutritional product, it is characterized in that, the mode of the described employing low temperature of second step (2) is carried out drying to initial fermented glutinous rice or initial brewing fermentation product, is the process that realizes limit drying, limit fermentation or keep fermentation in drying.
5, according to claim 1 the fermented glutinous rice nutrients or the wine brewing nutritional product, it is characterized in that, the mode of the described employing low temperature of second step (2) is carried out in drying initial fermented glutinous rice or initial brewing fermentation product, and the drying mode of selection is: the oven dry of A. drying under reduced pressure or B. drying room or baking oven or C. dry or any combination of a kind of or above-mentioned drying mode of E. that D. dries naturally.
6, according to claim 1 the fermented glutinous rice nutrients or the wine brewing nutritional product, it is characterized in that, the mode of the described employing low temperature of second step (2) is carried out in drying initial fermented glutinous rice or initial brewing fermentation product, the standard of the baking temperature of selecting is: under this baking temperature, the probio that can not kill or can not kill in large quantities in fermented glutinous rice is as the criterion, described probio refers to the rhizopus, Aspergillus, Bacillus acidi lactici, the saccharomycete that use in conventional brewing method, or with its combination, particularly with the combination of rhizopus, or the combination of multiple bacterium.
7, according to claim 1 the fermented glutinous rice nutrients or the wine brewing nutritional product, it is characterized in that, fermentation described in the first step (1) prepares in initial fermented glutinous rice or initial brewing fermentation product, needs according to working condition, fermentation temperature is at 15-40 ℃, and fermentation time is to be advisable in 8-48 hour; Or fermentation temperature is at 25-35 ℃, and fermentation time was advisable at 16-28 hour.
8, according to claim 1 the fermented glutinous rice nutrients or the wine brewing nutritional product, it is characterized in that, the mode of the described employing low temperature of second step (2) is carried out in drying initial fermented glutinous rice or initial brewing fermentation product, the baking temperature of selecting be: according to the needs of working condition, baking temperature is to allow its drying in 0-60 ℃ or 10-40 ℃ or 20-35 ℃.
Or fermented glutinous rice nutrients according to claim 1 or wine brewing nutritional product, it is characterized in that, the mode of the described employing low temperature of second step (2) is carried out in drying initial fermented glutinous rice, the standard of the drying time of selecting is: according to the needs of working condition, be to be advisable in 24-172 hour drying time, being perhaps 72-124 hour, is perhaps 80-96 hour, slowly allows its drying.
9, the preparation method of the nutritional product of a kind of fermented glutinous rice nutrients or wine brewing, is characterized in that, adopted step (1) in claim 1-8 any one and the step of (2).
10, the application form of the fermented glutinous rice nutrients of any one of claim 1-8 or wine brewing nutritional product, it is characterized in that, on the basis of step (2), further be prepared into the fermented glutinous rice nutrients of different dosage form form or initial brewing fermentation product, the different dosage form form of described fermented glutinous rice nutrients or initial brewing fermentation product is: the A. drying is to moisture below 20%, pulverize, obtain nutrient powder, B. drying is to moisture below 50%, add auxiliary material, pulverize, obtain nutrient powder, C. drying is to moisture below 80%, be prepared into oral liquid or other semi-solid or viscid nutriment,
Perhaps, with described fermented glutinous rice nutrients or the wine brewing nutritional product for the preparation of various forms of food, health food, food ingredient, food additives, nutritious supplementary pharmaceutical, fermented glutinous rice sugar, fermented glutinous rice beverage, medicine and animal feed, forage compounding, feed addictive, the nutraceutical consumption of fermented glutinous rice is generally all at 0.1-99.9%:
Perhaps, in described fermented glutinous rice nutrients or wine brewing nutritional product, add animals and plants, Chinese medicine or animals and plants, the Chinese medical extract of any one or multiple edible or medicinal efficacy, to be prepared into food or health food or the medicine that contains functional component;
Perhaps, described fermented glutinous rice nutrients or wine brewing nutritional product form composition with honey and are prepared into nutrient candy and food, as are made into fermented glutinous rice halavah, fermented glutinous rice honey cake and fermented glutinous rice honey paste (or congee); Its composite formula ratio is fermented glutinous rice nutrients or wine brewing nutritional product 5.0-9.9 part: honey 0.1-5.0 part, and especially formula rate is fermented glutinous rice nutrient powder 8-9.5 part: most suitable during honey 0.5-2 part;
Perhaps, be prepared into nutrient candy and health food with conventional method; As be made into fermented glutinous rice sesame seed candy, fermented glutinous rice sesame, fermented glutinous rice sesame mush (or congee); Its composite formula ratio is fermented glutinous rice nutrients or wine brewing nutritional product 5.0-9.0 part: honey 0.5-3.0 part: sesame 0.5-2.0 part; Especially formula rate is at fermented glutinous rice nutrients or wine brewing nutritional product 7.0-8.5 part: honey 0.5-1.5: most suitable during sesame 0.5-1.5 part;
Perhaps, be prepared into nutrient candy and health food with conventional method; As be made into fermented glutinous rice pachymose, fermented glutinous rice tuckahoe cake, fermented glutinous rice Poria cocos mush (or congee) and fermented glutinous rice Poria cocos biscuit; Or fermented glutinous rice radix puerariae sugar, fermented glutinous rice root of kudzu vine cake, fermented glutinous rice root of kudzu vine mush (or congee) and fermented glutinous rice root of kudzu vine biscuit; Its composite formula ratio is fermented glutinous rice nutrients or wine brewing nutritional product 5.0-9.8 part: honey 0.1-2.0 part: Poria cocos or root of kudzu vine 0.1-3.0 part; Especially formula rate is fermented glutinous rice nutrients or wine brewing nutritional product 7.5-9.0 part: honey 0.5-1.0: most suitable when Poria cocos or root of kudzu vine 0.5-1.5 part;
Perhaps, be prepared into health products or medicine with conventional method; As being made into fermented glutinous rice astragalus oral liquid or electuary or granule, its composite formula ratio is fermented glutinous rice nutrients or wine brewing nutritional product 5.0-9.8 part: Radix Astragali ethanol extract 0.1-3.0 part: especially formula rate is fermented glutinous rice nutrients or wine brewing nutritional product 7.5-9.0 part: most suitable during Radix Astragali ethanol extract 0.5-1.0 part;
Perhaps, be prepared into health products or medicine with conventional method; As being made into fermented glutinous rice Radix Astragali ass glue oral liquid or electuary or granule or pill, its composite formula ratio is fermented glutinous rice nutrients or wine brewing nutritional product 5.0-9.8 part: Radix Astragali ethanol extract 0.1-2.0 part: donkey-hide gelatin 0.1-3.0 part; Especially formula rate is fermented glutinous rice nutrients or wine brewing nutritional product 7.5-9.0 part: Radix Astragali ethanol extract 0.5-1.0: most suitable during donkey-hide gelatin 0.5-1.5 part;
Perhaps, be prepared into health products or medicine with conventional method; As being made into fermented glutinous rice glossy ganoderma fleece-flower root oral liquid or electuary or granule or pill, its composite formula ratio is fermented glutinous rice nutrients or wine brewing nutritional product 4.0-9.7 part: glossy ganoderma ethanol extract or water topic thing 0.1-2.0 part: Poria cocos ethanol extract or water topic thing 0.1-2.0 part: fleece-flower root ethanol extract or water extract 0.1-2.0 part; Especially formula rate is fermented glutinous rice nutrients or wine brewing nutritional product 7.0-9.7 part: glossy ganoderma ethanol extract or water extract 0.5-1.0: Poria cocos ethanol extract or water extract 0.1-1.0 part: most suitable when fleece-flower root ethanol extract or water extract 0.5-1.0 part;
Perhaps, be prepared into food, health products or medicine with conventional method; As being made into fermented glutinous rice kidney-tonifying and yang-strengthening oral solution or electuary or granule or pill, its composite formula ratio is fermented glutinous rice nutrients or wine brewing nutritional product 4.0-9.8 part: Chinese yam 0.1-2.0 part: pumpkin seeds benevolence 0.1-2.0 part; Fruit of Chinese wolfberry 0.5-2.0 part, especially formula rate is fermented glutinous rice nutrients or wine brewing nutritional product 7.0-9.0 part: Chinese yam 0.5-1.0 part: pumpkin seeds benevolence 0.2-1.0 part; Most suitable during fruit of Chinese wolfberry 0.3-1.0 part;
Perhaps, the purposes of the fermented glutinous rice nutrients of according to claim 1-8 any one or wine brewing nutritional product is: be used for bread and cheese, or be used for the treatment of leucocyte, red blood cell and thrombocytopenia, or promote health products and the medicine of leucocyte, red blood cell and platelet levels; Or can be used as adjuvant drug with tumour and cancer patient's radiotherapy, chemotherapy and surgical postoperative patient; Or can be used as be used for the treatment of men and women's sexual disorder and the requirement of raising property or improve health products and medicine sleep or that calm the nerves; Or be made into food, health products and the medicine that promotes infant development.
Perhaps, described fermented glutinous rice nutrients or wine brewing nutritional product are made the dosage form of various food or health products or medicine, comprise powder, pill, granule, electuary, tablet, oral liquid and liquid beverage, the preparation of solid beverage and pie shape, bar shaped and block shape; In case of necessity, the traditional auxiliary material that adds.
Two, the terminological interpretation of technical scheme:
Wine brewing is to utilize microbial fermentation production to contain the process of finite concentration alcoholic beverage.
The wine brewing nutritional product, the definition of corresponding above-mentioned wine brewing refers to method of the present invention, in the wine brewing process, adopts the fermentation of step (1), and the dry run of step (2), the wine brewing nutritional product with nutritional labeling that finally obtains.
Fermented glutinous rice or be rice wine, have another name called fermented glutinour rice, ancients are " sweet wine ".Primary raw material is glutinous rice (glutinous rice), so also be glutinous rice wine or be glutinous rice wine.Fermented glutinous rice claims generally that in the north it is " rice wine " or " sweet wine ", is made by distiller's yeast (mainly comprise rhizopus etc. have fermentation, saccharification, benefit the bacterium of one or more functions such as give birth to and form).
The fermented glutinous rice nutrients, a kind of two step method method preparation of the present invention (1) and (2) is adopted in the definition of corresponding above-mentioned fermented glutinous rice, and the procedure of processing of some conventional fermented glutinous rice or wine brewing, take glutinous rice or rice as raw material, the product that contains nutritional labeling for preparing.These products can be dry fermented glutinous rice pressed powders, and the granularity of its pulverizing can be regulated as required, and fermented glutinous rice nutrients of the present invention is to obtain by the step of fermenting.Therefore, fermented glutinous rice nutrients or wine brewing nutritional product also can be referred to as fermented glutinous rice or brewing fermentation thing, fermented glutinous rice or wine brewing nutrition yeast powder, fermented glutinous rice or brewing fermentation powder etc.Fermented glutinous rice nutrients of the present invention, color are white or slightly little yellowish pressed powder, and the content of the distinguish the flavor of natural fragrance sweet, that fermented glutinous rice is arranged and ethanol is very low.
Drying mode, drying mode of the present invention can be selected from the oven dry of drying under reduced pressure, drying room or baking oven, one or more the combination of drying, drying.If preparation fermented glutinous rice or brewing fermentation powder, should make the product of fermented glutinous rice or wine brewing be dried to moisture is in the 0.1-20% scope, is beneficial to pulverize.
Three, the invention provides a kind of fermented glutinous rice nutrients, main feature and the advantage of its preparation method are:
1, sweat is flexible, and easily grasps.For example, the fermentation described in the first step (1) prepares in initial fermented glutinous rice or initial brewing fermentation product, and according to the needs of working condition, fermentation temperature is at 15-40 ℃, and fermentation time is to be advisable in 8-48 hour; Or fermentation temperature is at 25-35 ℃, and fermentation time was advisable at 16-28 hour; The mode of the described employing low temperature of second step (2) is carried out in drying initial fermented glutinous rice, the standard of the drying time of selecting is: according to the needs of working condition, be to be advisable in 24-172 hour drying time, is perhaps 72-124 hour, be perhaps 80-96 hour, slowly allow its drying.These processes under guidance of the present invention, are not easily grasped even do not have the common laborer of cultural knowledge yet.
2, this fermented glutinous rice nutrients has the nature antisepsis, does not add any anticorrisive agent, can place more than 12 months not corruptly after dry sealing in natural temperature, has the environmental protection characteristics; One of mechanism of its natural antisepsis may be, dry run makes moisture greatly reduce, and sugar part Enrichment has suppressed the harmful microbe growth, and the live probiotics itself that exists has bacteriostasis.Certainly, if in conjunction with adopting some conventional disinfecting actions, more be conducive to the prolongation of shelf-life.
3, product thing nutritive value of the present invention is high after measured, albumen and each seed amino acid and must amino acid, carotene, riboflavin, vitamin E higher than the fermented glutinous rice thing 3-5 of traditional handicraft preparation doubly, data that in detail can reference example.Especially be embodied on the component contents such as protein, amino acid.
4, the test of small white mouse antifatigue effect and raising immunity shows that the fermented glutinous rice nutrients group of patented method preparation is better than the fermented glutinous rice thing group of conventional method preparation; Mouse oral toxicity test shows fermented glutinous rice nutrients mouse maximal tolerance dose greater than 10gkg-1, prove the little or avirulence of toxicity, use safety.
5, this thing can be prepared into health food, nutrient candy and the medicine of various formulations, also can be prepared into health food, medicine with other food with health role or medicinal material prescription, and can be used as batching, auxiliary material and the additive use of food, health products and medicine.
Embodiment:
One, take glutinous rice as raw material, fermentation preparation fermented glutinous rice nutrients is example, and nutraceutical preparation technology is as follows for fermented glutinous rice
1. first water is with 6-10 hour (summer is shorter) of glutinous rice (also available rice) bubble, and rinsing is clean, cooks into rice, namely puts water in steamer, pad one deck gauze on steaming tray, and heating up water has boiled to steam.Glutinous rice is dragged for to be placed on cloth cook, taste the mouthfeel of rice grain, if rice grain is partially hard, just spill again a little water and mix steaming more for a moment, steamed rear rice contain the fermentation use container in, stir and spill mineral water (or cold water) its cooling with spoon, cool to non-scald on hand (temperature 30 left and right) for well.Then prepare the fermented glutinous rice nutrients with two-step fermenting.
2. the first step: mix distiller's yeast and fermentation
With spoon, rice is done to break up even, with a certain amount of distiller's yeast soluble in water (head mold making), be sprinkling upon equably on glutinous rice and (stay a little little by little last using), with spoon, rice is stirred, purpose is to be mixed distiller's yeast even as far as possible.And with spoon compacting gently, make terrace pyramid type, the middle depression nest that extrudes is sprinkling upon the inside with last point distiller's yeast and a small amount of water.Then container is covered tightly, be placed on (25-32 ℃ of left and right) fermentation at suitable temperature.If room temperature is inadequate, can container be wrapped heat-preservation fermentation with thick towel or cotton-wadded quilt etc.The centre can check, looks at mainly whether temperature is suitable.Just can taste or observe after general 16-20 hour.Juice occurs, or occur little by little that fragrance and sweet can stopping ferment.
3. second step: fermentation dried and make finished product
It is dried or low temperature drying (temperature 25-35 ℃ of left and right), dry or dry and to surpass 72 hours, make it slowly fermentation dried.Insufficient and not enough if ferment, but time of proper extension drying (be actually allow it continue fully fermentation, the drying while ferment) also.Make at last the fermented glutinous rice nutrients, taste very fragrant and sweet.
Two, take wheat as raw material, fermentation preparation wine brewing nutrients or wine brewing nutritional product are that the preparation technology of example is as follows
1. the saccharification of Fructus Hordei Germinatus: adopt the intensification infusion mashing, carry out saccharification.First utilize water at low temperature 35-38 degree dipping Fructus Hordei Germinatus, time 0.5-1 hour; Be warmed up to 50 degree, carry out protein and decompose, kept about 40 minutes; Slowly be warmed up to the 62-63 degree, saccharification is about 30 minutes again; Continue intensification 68-70 degree, until saccharification fully; Be warmed up at last 78 degree, stop saccharification.
2, the filtration of brewer's wort: with above-mentioned saccharification completely the Fructus Hordei Germinatus wine with dregs filter, obtain brewer's wort.
3, boiling of brewer's wort: adopt traditional batch (-type) normal pressure boiling method, boiling time 70-90 minute; In boiling part, add appropriate hops 0.01-0.08%.
4, adjust the concentrated of brewer's wort: as required brewer's wort is concentrated, be concentrated near solid state.
5, the fermentation of Fructus Hordei Germinatus and drying (two step method): add beer yeast fermenting, fermentation just can be tasted or be observed after general 16-20 hour.Juice occurs, or the fragrant and sweet fermentation that can stop occurs, it is dried or low temperature drying (temperature 25-35 ℃ of left and right), dry or dry and to surpass 72 hours, make it slowly dry.Insufficient and not enough if ferment, but time of proper extension drying (be actually allow it continue fully fermentation, the drying while ferment) also.Make at last the wine brewing nutritional product, taste very fragrant and sweet, with the taste of beer.
Three, take glutinous rice and corn as mixed material, fermentation preparation wine brewing nutrients or wine brewing nutritional product are that the preparation technology of example is as follows
1. first water mixes glutinous rice (0.1-9.9 part) with corn fine-grained powder (0.1-9.9 part), steep (summer is shorter) rinsing in 8-12 hour clean, pad one deck gauze on steaming tray, glutinous rice is dragged for to be placed on cloth cook, taste the mouthfeel of rice grain, if rice grain is partially hard, just spill again a little water and mix steaming more for a moment, in the steamed rear container of rice being contained fermentation use, with spoon stirring with spill mineral water (or cold water) its cooling, cool to non-scald on hand (temperature 30 left and right) for well.Then prepare the fermented glutinous rice nutrients with two-step fermenting.
2. the first step: mix distiller's yeast and fermentation
With spoon, rice is done to break up even, with a certain amount of distiller's yeast soluble in water (head mold making), be sprinkling upon equably on glutinous rice and (stay a little little by little last using), with spoon, rice is stirred, purpose is to be mixed distiller's yeast even as far as possible.And with spoon compacting gently, make terrace pyramid type, the middle depression nest that extrudes is sprinkling upon the inside with last point distiller's yeast and a small amount of water.Then container is covered tightly, be placed on (25-32 ℃ of left and right) fermentation at suitable temperature.If room temperature is inadequate, can container be wrapped heat-preservation fermentation with thick towel or cotton-wadded quilt etc.The centre can check, looks at mainly whether temperature is suitable.Just can taste or observe after general 16-20 hour.Juice occurs, or occur little by little that fragrance and sweet can stopping ferment.
3. second step: fermentation dried and make finished product
It is dried or low temperature drying (temperature 25-35 ℃ of left and right), dry or dry and to surpass 72 hours, make it slowly fermentation dried.If everfermentation, fermented glutinous rice is too much, can add a certain amount of glutinous rice or corn dry powder, preferably ripe dry powder.Insufficient and not enough if ferment, but time of proper extension drying (be actually allow it continue fully fermentation, the drying while ferment) also.Make at last the fermented glutinous rice nutrients, taste very fragrant and sweet.
Four, the comparison of active ingredient
Press the fermented glutinous rice nutrients of the fermentation of the described method of this patent and dry preparation, according to the detection to the main component of this thing, every 100 grams contain albumen and each seed amino acid and must amino acid etc. main nutrient composition prepare 3-5 times of fermented glutinous rice thing apparently higher than conventional method.
In addition, the yield by the described method gained of this patent fermented glutinous rice nutrients (dry powder) prepares fermented glutinous rice gains (if also carrying out drying) yield higher than 2-3 doubly than conventional method.
The below simply concludes, and this patent prepares fermented glutinous rice nutrients and traditional wine method for brewing (seeing Table 1).
Table 1 patented method prepares fermented glutinous rice nutrients and the fermented glutinous rice of conventional method preparation and the difference of related products
Specific embodiment
One, Preparation Example
1, the nutraceutical product batch number of fermented glutinous rice of the present invention is 20110101, and referred to as fermented glutinous rice nutrients or fermentate, except indicating especially, following related experiment all adopts fermented glutinous rice nutrients or the yeast powder of this lot number.Concrete production process is as follows:
(1) first water steeps glutinous rice 8 hours, and rinsing is clean, then puts water in steamer, pad one deck gauze on steaming tray, and heating up water has boiled to steam.Glutinous rice is dragged for to be placed on cloth cook, taste the mouthfeel of rice grain, if rice grain is partially hard, just spill again a little water and mix steaming more for a moment, in the steamed rear container of rice being contained fermentation use, with spoon stirring with spill mineral water it is lowered the temperature, cool to non-scald on hand (30 ℃ of temperature).Then prepare the fermented glutinous rice nutrients with two-step fermenting.
(2) first step: mix distiller's yeast and fermentation
Do to break up rice even with spoon, to be dissolved in a certain amount of distiller's yeast in mineral water (commercially available) (commercially available, as mainly to comprise the probio such as rhizopus etc.), be sprinkling upon equably on glutinous rice (stay a little little by little last with), with spoon, rice is stirred, purpose is to be mixed distiller's yeast even as far as possible.And with spoon compacting gently, make terrace pyramid type, the middle depression nest that extrudes is sprinkling upon the inside with last point distiller's yeast and a small amount of water.Then container is covered tightly, be placed on (30 ℃ of fermentations stop fermentation after 18 hours) at the temperature of 30 ℃.
(3) second step: fermentation dried and making finished product
With the fermented glutinous rice that ferments, its low temperature drying (constant temperature blast drying oven, 30 ℃ of temperature), with 75 hours fermentation dried, then make dry powder, should according to actual conditions, stir in drying course.
2, the making of the common fermented glutinous rice powder of contrast: the product batch number of fermented glutinous rice powder is (20110102): the front operation is the same, with the fermented glutinous rice that ferments, it is dried (constant temperature blast drying oven according to normal baking temperature, temperature 70 C), in 24 hours, dry powder is made in oven dry, should according to actual conditions, stir in drying course.
Two, small white mouse antifatigue pharmacology test
Contrast negative medicine: physiological saline.
Contrast positive drug: commercially available " general tonic pill ".
Related documents method (Qi Chen chief editor's herbal pharmacology methodology is pressed in experiment, 1993); 60 of the accurate small white mouses of label taking, body weight 18-21g, male and female half and half; weigh respectively, number; be divided at random four groups by body weight, sex, first group is fermented glutinous rice nutrients of the present invention (product batch number is 20110101), second group is that the preparation fermented glutinous rice thing group lot number of conventional method is (20110102); the 3rd group is the blank group, and the 4th group is the general tonic pill group.Routine feeding 3d conforming, is subjected to weigh before test product, every gavage according to dosage, and the blank group is fed the physiological saline of same dose.Before experiment, two kinds of fermented glutinous rice powder are prepared into the oral liquid of Isodose, give continuously and feed 10d, every day 1 time.30min after giving trial target on the 10th day weighs in, and at afterbody bundle heavy burden thing 1 gram, mouse is put into respectively bathtub, bathtub water 18cm, interior swimming between water temperature 23-25 ℃, and beginning timing.Till can not emerging from the mouse entry to its head submerged 10s, the time therebetween is the duration of mouse swimming, and experimental data is carried out statistical procedures, the results are shown in Table 2.
The test of table 2 small white mouse antifatigue pharmacology test small white mouse antifatigue pharmacology (x ± s)
Annotate: testing one group is the fermented glutinous rice nutrient powder group of patented method preparation, and testing two groups is the fermented glutinous rice powder group of conventional method preparation
This experimental result shows that the fermented glutinous rice nutrient powder group of patented method preparation and the fermented glutinous rice powder group of conventional method preparation carry out statistics t check comparison, and the former is better than the latter its antifatigue effect, and dose-effect relationship has significant difference (P＜0.01).
Three, fermented glutinous rice nutrients rising PBL animal pharmacology research
(1) the leukocytic experimental study of fermented glutinous rice nutrients rising mouse peripheral blood
Medicine and reagent: prepare the oral liquid of Isodose during fermented glutinous rice nutrient powder (self-produced: as to produce certification 20110101) experiment, endoxan (CTX), powder-injection, 200mg/ bottle, Hualian Pharmaceutical Co., Ltd., Shanghai's product, lot number: 110320; Benzene, purity are 1199.5, Beijing North fine chemicals Co., Ltd, lot number: 1109432;Using mouse is bright kind of mouse, SPF level, ♀ ♂ half and half, body weight (20 ± 2).
Statistical method: experimental data is used SPSS software and is carried out variance analysis, the F check.Between each group, average relatively adopts the q check.(x ± s) expression, significance level and result judgement are by general hypothesis testing standard with mean ± standard deviation for result.
Rising Induced by Cyclophosphamide mouse peripheral blood total white blood cells lowly acts on experiment and establishes 5 groups, 12 every group, is respectively the blank group, model control group, fermented glutinous rice nutrient powder 0.5g/kg group, 1.0g/kg group, 2.0g/kg group (respectively referred to as fermented glutinous rice nutrient powder 1,2,3 groups).Each organizes equal ig administration, and 1 time/d, totally 13 days.Fermented glutinous rice nutrient powder 1.0g/kg, 2.0g/kg and 4.0g/kg3 dosage group are respectively with 10 times (1.0g/kg) of clinical Coming-of-Age Day dosage (0.25g/kg), 20 times (1.0g/kg) and 40 times (2.0g/kg).All the other respectively organized equal ip endoxan 100mg/kg1 time except the blank group in the 7th day in administration, 1h after administration in the 10th, 13 day (after being ip CTX the 3rd, 6 day), and the tail venous blood sampling is measured total white blood cells.Data is all so that (x ± s) expression, between the employing group, statistical procedures is carried out in the t test.Result: with model control group relatively, give after endoxan the 3rd day, fermented glutinous rice nutrient powder 0.5g/kg, 1.0g/kg and 2.0g/kg group total white blood cells all obviously raise.Show that the fermented glutinous rice nutrient powder has the rising Immunosuppressant Cyclophosphamide and brings out the mouse peripheral blood leucocyte and lowly act on.The low effect of fermented glutinous rice nutrient powder rising Induced by Cyclophosphamide mouse peripheral blood total white blood cells is compared with model group, and three groups are respectively P＜0.05, P＜0.01, and P＜0.001, particularly high dose group (2.0g/kg) effect is best.
The effect of fermented glutinous rice nutrient powder rising benzene poisoning mouse peripheral blood total white blood cells, before experiment, the preliminary election mouse tail is got blood, measures the PBL sum, gets the WBC total value in (10～12) * 10
9The mouse of/L is for the experiment modeling.Mouse sc99.5% benzene 5ml/kg contamination, 1 time/d, continuous 5 days, get hematometry mouse WBC sum, when mouse WBC sum is down to 50%～60%, be considered to the moulding success.Then, be divided into 4 groups by mouse WBC sum, every group of 12 mouse are respectively: benzene contamination model group; Fermented glutinous rice nutrient powder 1.0g/kg group; The YXL2.0g/kg group; Fermented glutinous rice nutrient powder 4.0g/kg group.Each organizes 5 days (contaminating altogether 10 days) of mouse continuation sc benzene contamination, and in the 7th contamination simultaneously, each organizes ig administration every day respectively 1 time, continuous 15 days YXL.1h gets hematometry WBC sum after administration in the 8th, 15 day.Data is all so that (x ± s) expression, between the employing group, statistical procedures is carried out in the t check.Result: with model group relatively, fermented glutinous rice nutrient powder ig8 days 1.0g/kg, 2.0g/kg, ig15 days 0.5g/kg, 1.0g/kg and 2.0g/kg group all can obviously raise, and periphery WBC lowly acts on due to the benzene poisoning mouse.Show that the fermented glutinous rice nutrient powder has rising benzene poisoning mouse peripheral blood leucocyte and lowly acts on.
Four, the toxicity test of small white mouse maximal tolerance dose
The nutraceutical product batch number of fermented glutinous rice of the present invention is (20110103, the preparation method is with 20110101 batches), and presses the related documents method; 60 of the accurate small white mouses of label taking, body weight 18-21g, male and female half and half; weigh respectively, number are divided into three groups at random by body weight, sex, 20 every group.First group is one group of experiment, feeds the fermented glutinous rice nutrients 8g/kg of the invention described above; Second group is two groups of experiments, feeds the dry thing 10g/kg of fermented glutinous rice of the invention described above; The 3rd group is physiology saline control group.The experiment before the animal fasting can't help water 12h, during experiment in one day every mouse give tested material by gavage, Continuous Observation 7 days.After result shows 7 days of three groups of mouse life in order, without the phenomena of mortality.Therefore record the maximal tolerance dose (MTD) of mouse 〉=10g/kg.Prove that the inspection of the very low or avirulence of this fermented glutinous rice nutrient powder toxicity or its toxicity does not measure, can be used as that a kind of safety food uses or health food uses.
Fermented glutinous rice nutrients of the present invention also has following effect
(1) effect of traditional fermented glutinous rice, for example, the effect such as increase newborn effect, beneficial gas, promote the production of body fluid, invigorate blood circulation.
(2) fermented glutinous rice nutrients of the present invention contains abundant beneficial bacterium, as rhizopus, Aspergillus, Bacillus acidi lactici, saccharomycete, can fully regulate functions of intestines and stomach.
(3) polysaccharide of fermentation generation, polypeptide etc. can improve the effects such as immunity of organisms, antifatigue and living leucocyte ability.
Five, the amino acid of fermented glutinous rice nutrients (nutrient powder, producing lot number is 20120101) and the check of protein
In order further to verify the value of fermented glutinous rice nutrient powder of the present invention, I have prepared this invention fermented glutinous rice nutrient powder again, product batch number is 20120101, the preparation method is with 20110101 batches, and entrust the authoritative institution of instrument test analysis center of the Chinese military medicine academy of sciences, yeast powder of the present invention (being the fermented glutinous rice nutrient powder of above-mentioned lot number 20120101) is tested.
After detection, as can be known, the nutritive value of yeast powder of the present invention is high, various food or the health foods take fermented glutinous rice as raw material that are far superior to see in the market.Detailed data shows, fermented glutinous rice nutrient powder of the present invention has 13 kinds of free amino acids, and accumulative total content reaches 168.3mg/g, and wherein lysine is 46.5mg/g; Each seed amino acid after hydrolysis is also very high, and wherein smart amino acid is up to 29.39mg/g; The content of gross protein is 293.2mg/g; The content of total reducing sugar is 83.3mg/g.This shows, the nutritive value of yeast powder of the present invention is very high, and the content of sugar is lower, is genuine fermented glutinous rice nutrient powder.
Further, analyze the data of the above results, except various amino acid contents are very high, also have following features: (1) leucine can promote sleep; (2) histidine and arginine promote infant development; (3) arginine and phenylalanine are conducive to improve male sex's sexual desire; (4) threonine can improve immunity; (5) methionine Wheat Protein; (6) lysine and phenylalanine can improve memory and improve energy and concentrate, and lysine can also obviously promote brain development; (7) methionine, isoleucine, valine and histidine can promote hemoglobin, leukocytic generation; (8) TYR can prevent senile dementia.
Six, preparation and the implementation example of fermented glutinous rice nutrients related products and composition related products
The preparation that example 1, fermented glutinous rice sugar, fermented glutinous rice are stuck with paste (or particle electuary), fermented glutinous rice beverage
(1) get 5 kilograms of fermented glutinous rice nutrient powder, directly pulverize, sieve, make fermented glutinous rice paste or fermented glutinous rice particle electuary that granule is prepared into block fermented glutinous rice sugar shape or ball shape of gram about the 5-7 gram with traditional method or is prepared into the small package bag about 20 grams.
(2) get 5 kilograms of fermented glutinous rice nutrient powder, be prepared into non-alcoholic beverages with traditional method.This beverage can be to have after slag beverage (oral liquid) or simple filtration without the slag beverage.
The preparation that example 2, fermented glutinous rice halavah, fermented glutinous rice honey cake and fermented glutinous rice honey are stuck with paste
Take 1 kilogram of 9 kilograms of fermented glutinous rice nutrient powder (9 parts) and honey (1 part), stir, pulverize, sieve, make granule, be prepared into the fermented glutinous rice honey sugar of the block shape of gram about the 4-8 gram or the fermented glutinous rice halavah of ball shape with traditional method, or be prepared into fermented glutinous rice honey paste, granule or the electuary of the small package bag of about 10-20 gram, or be prepared into 8-12 gram left and right little book square fermented glutinous rice honey cake.
The preparation of example 3, fermented glutinous rice sesame seed candy, fermented glutinous rice sesame and fermented glutinous rice sesame cream
Take 8 kilograms of fermented glutinous rice nutrient powder (8 parts), honey 1 kilogram of (1 part) and Semen sesami nigrum (1 part), stir, pulverize, sieve, make granule, be prepared into the fermented glutinous rice sesame sugar of the block shape of gram about the 5-7 gram or the fermented glutinous rice sesame seed candy of ball shape with traditional method, or be prepared into fermented glutinous rice sesame cream granule or the fermented glutinous rice sesame cream electuary of the small package bag of about 10-30 gram, or be prepared into 8-20 gram left and right little book square fermented glutinous rice sesame.
The preparation of example 4, fermented glutinous rice pachymose, fermented glutinous rice tuckahoe cake, fermented glutinous rice Poria cocos congee and fermented glutinous rice Poria cocos biscuit
Take 7 kilograms of fermented glutinous rice nutrient powder (7 parts), honey 1 kilogram of (1 part) and 2 kilograms, Poria cocos (2 parts), stir, pulverize, sieve, make granule, be prepared into fermented glutinous rice Poria cocos Poria cocos sugar or the pill of the block shape of gram of about 4-8 gram or the fermented glutinous rice Poria cocos that is prepared into the small package bag of 10-20 gram left and right with traditional method and stick with paste granule or electuary or be prepared into 8-20 gram left and right little book square fermented glutinous rice tuckahoe cake or be prepared into the fermented glutinous rice Poria cocos biscuit of the circle (or square) of 10-20 gram left and right.
The product of above all trial-productions comprises fermented glutinous rice sugar, fermented glutinous rice paste (or particle electuary), fermented glutinous rice beverage, fermented glutinous rice halavah, fermented glutinous rice honey cake, fermented glutinous rice honey paste, fermented glutinous rice sesame seed candy, fermented glutinous rice sesame, fermented glutinous rice sesame cream, fermented glutinous rice pachymose, fermented glutinous rice tuckahoe cake, fermented glutinous rice Poria cocos congee and fermented glutinous rice Poria cocos biscuit etc.Through on probation, mouthfeel is good, and nutrition is high, is subjected to very much everybody joyful.
Example 5, use as food nutrition batching and additive
Prepare in tradition in the food such as biscuit, egg roll, fragrant revive ball, noodles, instant noodles, dairy produce and lotus seed soup, all can add the fermented glutinous rice xeraphium of 10-50%.Prepared fermented glutinous rice biscuit, fermented glutinous rice egg roll, the fragrant revive ball of fermented glutinous rice, fermented glutinous rice noodles, fermented glutinous rice instant noodles, milk fermented glutinous rice cake and lotus seeds fermented glutinous rice custard etc., the product special taste, nutrition is higher, also is subjected to very much everybody joyful.
The preparation of example 6, laboratory sample 1:
For the further value of checking fermented glutinous rice nutrient powder of the present invention, I have prepared this invention fermented glutinous rice nutrient powder again, and product batch number is more than 20120102,100 kilogram, the method for preparation method similar front lot number 20110101, and concrete production process is as follows:
(1) first water steeps glutinous rice 8 hours, and rinsing is clean, and then cook into rice and put water in steamer, pad one deck gauze on steaming tray, heating up water has boiled to steam.Glutinous rice is dragged for to be placed on cloth cook, taste the mouthfeel of rice grain, if rice grain is partially hard, just spill again a little water and mix steaming more for a moment, in the steamed rear container of rice being contained fermentation use, with spoon stirring with spill mineral water it is lowered the temperature, cool to non-scald on hand (30 ℃ of temperature).
(2) mix distiller's yeast and fermentation
With spoon, rice is done to break up even, will be dissolved in the distiller's yeast (head mold is made, and is commercially available) in mineral water (commercially available), be sprinkling upon equably on glutinous rice and (stay a little little by little last using), with spoon, rice is stirred, purpose is to be mixed distiller's yeast even as far as possible.And with spoon compacting gently, make terrace pyramid type, the middle depression nest that extrudes is sprinkling upon the inside with last point distiller's yeast and a small amount of water.Then container is covered tightly, be placed on (30 ℃ of fermentations stop fermentation after 16 hours) at the temperature of 30 ℃.
(3) fermentation dried and making finished product
With the fermented glutinous rice that ferments, its low temperature drying (constant temperature blast drying oven, 25 ℃ of temperature), then fermentating drying made dry powder more than 72 hours, added appropriate auxiliary material, as honey or sesame or medicinal material.Edible for human body, when edible, according to trier's hobby, the form of pill or oral liquid or suspension that the fermented glutinous rice nutrients is made is taken.
Seven, clinic trial statistical analysis and special case report
(1) clinic trial statistical analysis
1, experimental technique
(1) 74 healthy not good volunteer of people, age 40-65 year, be divided into after diagnosing three groups, first group, 23 people, the male sex 9 people, women 14 people are the problem of long-term existence sleep puzzlement; Second group, 25 people are all the male sex, and long-term sexual desire is not strong, lassitude, and appetite is not strong; The 3rd group, 26 people, the male sex 12 people, women 14 people, after suffering from tumour, hypoimmunity after chemotherapy, the low patient of leucocyte.
(2) foretaste, eat twice every day, eat fermented glutinous rice nutrient powder 18-20 gram (referring to the content in preparation) at every turn, took continuously for 4 weeks.
(3) foretaste result as follows.
Indicate: first group obviously is improved as sleep quality and improves, every day sack time more than 7 hours, and with take before compare and increase more than 2 hours; Be improved as the every day sack time more than 6 hours, and with take before compare and increase more than 2 hours; Invalid is unchanged.
Second group obviously is improved as the raising of sexual desire quality, and number of times is more than 5 times per month; Be improved as the sexual desire quality and improve, number of times is more than 3 times per month; Invalid is unchanged.
The 3rd group obviously is improved as the leucocyte increase, and ferroheme obviously improves; Be improved as the state of mind and take a turn for the better, physique increases, and appetite increase or leucocyte, ferroheme increase; Invalid is unchanged.
(2) clinical special case report
1, sleep quality improves case for example
Example 1. thanks to XX, the male sex, 52 years old, can sleep every day 3-5 hour, bad because sleeping, the state of mind is not good enough, often work can not be concentrated, and eats afterwards fermented glutinous rice honey ball every day, sooner or later respectively once, each two balls (every ball contains a kind of fermented glutinous rice nutrient powder 10g, Poria cocos 1g, honey 1g), after first quarter moon, sleep is obviously got better, the state of mind is improved, and work can be concentrated, after January, it is normal that sleep recovers, and can sleep every day 7-8 hour.
The yellow XX of example 1., the women 39 years old, can sleep 4-5 hour every day, just be difficult for falling asleep after often waking up in the sleep way, bad because sleeping, the state of mind is not good enough yet, work can not be concentrated, and eats afterwards fermented glutinous rice sesame ball every day, sooner or later respectively once, each two balls (every ball contains a kind of fermented glutinous rice nutrient powder 9g, Poria cocos 1g, glossy ganoderma ethanol extract 0.02g, honey 1g), after first quarter moon, sleep is obviously got better, and the state of mind is improved, and work can be concentrated, after January, it is normal that sleep recovers, and can sleep every day 7-8 hour.
2, the raising case of sexual function for example
Example 1. is XX recklessly, the male sex, 52 years old, because sexual function obviously descends, can not carry out sexual intercourse one time, eat afterwards fermented glutinous rice sesame ball every day in two months, sooner or later respectively once, (every ball contains a kind of fermented glutinous rice nutrient powder 9g, sesame 1g, honey 1g, pumpkin seeds benevolence 0.5g to each two balls, fruit of Chinese wolfberry 1g), after first quarter moon, sexual function obviously increases, and needs sexual intercourse weekly once, every first quarter moon sexual intercourse sometimes three times.
Example 2. Liu XX, the male sex, 38 years old, because of hyperaphroisia, sexual function obviously descended, frequent anorthosis, perhaps weak too early, mood is very bad.Repeatedly seek medical advice and have no resolution.Took afterwards fermented glutinous rice sesame ball (every ball contains a kind of fermented glutinous rice nutrient powder 10g, sesame 1g, pumpkin seeds benevolence 0.5g, honey 1g), every day 2 times, each 2 balls.After January, seminal fluid obviously increases, and sexual function is obviously improved, and needs sexual intercourse in every four days once.
The all XX of example 3., the male sex, 32 years old, owing to being the general manager of company, busy many with affairs, sexual function obviously descended, and often can not erect, and is perhaps weak too early.Took afterwards fermented glutinous rice Chinese-wolfberry nutritive granule (often comprise fermented glutinous rice nutrient powder 9g, fruit of Chinese wolfberry 1g, sesame 1g, honey 1g is prepared into granule with conventional method) every day 2 times, each 2 balls.After first quarter moon, seminal fluid obviously increases, and sexual function is obviously improved, and needs sexual intercourse weekly 1-2 time.
3, clinical living high leukocytic case for example
Example 1. thanks to XX, the women, and 55 years old, because of the radiotherapy in hospital 3 times that suffers from breast cancer, leucocyte descended obviously, only has 1.7 * 10
9/ L drank this oral liquid one month afterwards, every day secondary, each 50ml (every bottle contains 10g fermented glutinous rice nutrient powder), after January, leucocyte rises to 3.7 * 10
9/ L.Further use, after three months, leucocyte recovers normal substantially.This oral liquid mouthfeel is better, also there are no obvious side effect.
The old XX of example 2., the male sex, 65 years old, because suffering from the liver cancer interventional therapy of being in hospital, leucocyte descended obviously, only has 1.9 * 10
9/ L drank this electuary one month afterwards, every day secondary, each two the bag (often comprise 10g fermented glutinous rice nutrient powder, the 2g Semen sesami nigrum is prepared into electuary with conventional method), leucocyte rose to 3.1 * 10 afterwards
9/ L.Further use, check after three months that leucocyte continues to rise.Between the operating period, there are no obvious side effect.
Example 3. grandson XX, the male sex, 28 years old, because of the cases with leukemia repeatedly chemotherapy of being in hospital, anaemia appears, and leucocyte, red blood cell and blood platelet descend obviously, and leucocyte only has 3.2 * 10
9/ L, red blood cell 3,200,000/mm
3,Blood platelet 80 * 10
9/ L drank this electuary one month afterwards, every day secondary, each 12g compound fermented glutinous rice nutrient powder electuary (quite 9.3g fermented glutinous rice nutrient powder, 1g honey, 1g Semen sesami nigrum, 0.5g donkey-hide gelatin, 0.2g Radix Astragali ethanol extract), leucocyte rose to 3.9 * 10 afterwards
9/ L, red blood cell 3,800,000/mm
3, blood platelet 100 * 10
9/ L continues to use, and after two months, leucocyte further rises.
Claims (10)
1. a fermented glutinous rice nutrients or the nutritional product of making wine, is characterized in that, adopts the two-step fermenting preparation, and its step is as follows:
(1) first step according to the common process of fermented glutinous rice preparation technology or wine brewing, prepares initial fermented glutinous rice or initial brewing fermentation product with fermenting raw materials;
(2) second step on the basis of step (1), adopts the mode of low temperature that initial fermented glutinous rice or initial brewing fermentation product are carried out fermentation dried or carries out the drying fermentation or drying in fermentation.
According to claim 1 the fermented glutinous rice nutrients or the wine brewing nutritional product, it is characterized in that, raw material described in step (1) is glutinous rice, rice, millet, wheat, corn, soybean, lotus seeds, coix seed, or arbitrary combination of above-mentioned raw materials or the combination of multiple thing, the particularly combination of glutinous rice and/or rice and other raw material different proportion;
Or in step (2), be in fermentation dried process or carry out drying fermentation or add powder when dry in fermentation, described powder is glutinous rice, rice, millet, wheat, corn, soybean, lotus seeds, coix seed, or arbitrary combination of above-mentioned raw materials or the combination of multiple thing, the particularly combination of glutinous rice and/or rice and other raw material different proportion.
According to claim 1 the fermented glutinous rice nutrients or the wine brewing nutritional product, it is characterized in that, the fermentation standard of the described initial fermented glutinous rice of the first step (1) or initial brewing fermentation product is: the initial fermented glutinous rice nest of A. can be seen the initial fermented glutinous rice of liquid or a little liquid or B. liquid can occur through slight extruding, or the initial fermented glutinous rice of C. has sweet taste or sweet taste slightly through trial test.
According to claim 1 the fermented glutinous rice nutrients or the wine brewing nutritional product, it is characterized in that, the mode of the described employing low temperature of second step (2) is carried out drying to initial fermented glutinous rice or initial brewing fermentation product, is the process that realizes limit drying, limit fermentation or keep fermentation in drying.
According to claim 1 the fermented glutinous rice nutrients or the wine brewing nutritional product, it is characterized in that, the mode of the described employing low temperature of second step (2) is carried out in drying initial fermented glutinous rice or initial brewing fermentation product, and the drying mode of selection is: the oven dry of A. drying under reduced pressure or B. drying room or baking oven or C. dry or any combination of a kind of or above-mentioned drying mode of E. that D. dries naturally.
According to claim 1 the fermented glutinous rice nutrients or the wine brewing nutritional product, it is characterized in that, the mode of the described employing low temperature of second step (2) is carried out in drying initial fermented glutinous rice or initial brewing fermentation product, the standard of the baking temperature of selecting is: under this baking temperature, the probio that can not kill or can not kill in large quantities in fermented glutinous rice is as the criterion, described probio refers to the rhizopus, Aspergillus, Bacillus acidi lactici, the saccharomycete that use in conventional brewing method, or with its combination, particularly with the combination of rhizopus, or the combination of multiple bacterium.
According to claim 1 the fermented glutinous rice nutrients or the wine brewing nutritional product, it is characterized in that, fermentation described in the first step (1) prepares in initial fermented glutinous rice or initial brewing fermentation product, needs according to working condition, fermentation temperature is at 15-40 ℃, and fermentation time is to be advisable in 8-48 hour; Or fermentation temperature is at 25-35 ℃, and fermentation time was advisable at 16-28 hour.
According to claim 1 the fermented glutinous rice nutrients or the wine brewing nutritional product, it is characterized in that, the mode of the described employing low temperature of second step (2) is carried out in drying initial fermented glutinous rice or initial brewing fermentation product, the baking temperature of selecting be: according to the needs of working condition, baking temperature is to allow its drying in 0-60 ℃ or 10-40 ℃ or 20-35 ℃.
Or fermented glutinous rice nutrients according to claim 1 or wine brewing nutritional product, it is characterized in that, the mode of the described employing low temperature of second step (2) is carried out in drying initial fermented glutinous rice, the standard of the drying time of selecting is: according to the needs of working condition, be to be advisable in 24-172 hour drying time, being perhaps 72-124 hour, is perhaps 80-96 hour, slowly allows its drying.
9. the preparation method of the nutritional product of a fermented glutinous rice nutrients or wine brewing, is characterized in that, adopted step (1) in claim 1-8 any one and the step of (2).
the fermented glutinous rice nutrients of any one of claim 1-8 or the wine brewing nutritional product application form, it is characterized in that, on the basis of step (2), further be prepared into the fermented glutinous rice nutrients of different dosage form form or initial brewing fermentation product, the different dosage form form of described fermented glutinous rice nutrients or initial brewing fermentation product is: the A. drying is to moisture below 20%, pulverize, obtain nutrient powder, B. drying is to moisture below 50%, add auxiliary material, pulverize, obtain nutrient powder, C. drying is to moisture below 80%, be prepared into oral liquid or other semi-solid or viscid nutriment,
Perhaps, with described fermented glutinous rice nutrients or the wine brewing nutritional product for the preparation of various forms of food, health food, food ingredient, food additives, nutritious supplementary pharmaceutical, fermented glutinous rice sugar, fermented glutinous rice beverage, medicine and animal feed, forage compounding, feed addictive, the nutraceutical consumption of fermented glutinous rice is generally all at 0.1-99.9%:
Perhaps, in described fermented glutinous rice nutrients or wine brewing nutritional product, add animals and plants, Chinese medicine or animals and plants, the Chinese medical extract of any one or multiple edible or medicinal efficacy, to be prepared into food or health food or the medicine that contains functional component;
Perhaps, described fermented glutinous rice nutrients or wine brewing nutritional product form composition with honey and are prepared into nutrient candy and food, as are made into fermented glutinous rice halavah, fermented glutinous rice honey cake and fermented glutinous rice honey paste (or congee); Its composite formula ratio is fermented glutinous rice nutrients or wine brewing nutritional product 5.0-9.9 part: honey 0.1-5.0 part, and especially formula rate is fermented glutinous rice nutrient powder 8-9.5 part: most suitable during honey 0.5-2 part;
Perhaps, be prepared into nutrient candy and health food with conventional method; As be made into fermented glutinous rice sesame seed candy, fermented glutinous rice sesame, fermented glutinous rice sesame mush (or congee); Its composite formula ratio is fermented glutinous rice nutrients or wine brewing nutritional product 5.0-9.0 part: honey 0.5-3.0 part: sesame 0.5-2.0 part; Especially formula rate is at fermented glutinous rice nutrients or wine brewing nutritional product 7.0-8.5 part: honey 0.5-1.5: most suitable during sesame 0.5-1.5 part;
Perhaps, be prepared into nutrient candy and health food with conventional method; As be made into fermented glutinous rice pachymose, fermented glutinous rice tuckahoe cake, fermented glutinous rice Poria cocos mush (or congee) and fermented glutinous rice Poria cocos biscuit; Or fermented glutinous rice radix puerariae sugar, fermented glutinous rice root of kudzu vine cake, fermented glutinous rice root of kudzu vine mush (or congee) and fermented glutinous rice root of kudzu vine biscuit; Its composite formula ratio is fermented glutinous rice nutrients or wine brewing nutritional product 5.0-9.8 part: honey 0.1-2.0 part: Poria cocos or root of kudzu vine 0.1-3.0 part; Especially formula rate is fermented glutinous rice nutrients or wine brewing nutritional product 7.5-9.0 part: honey 0.5-1.0: most suitable when Poria cocos or root of kudzu vine 0.5-1.5 part;
Perhaps, be prepared into health products or medicine with conventional method; As being made into fermented glutinous rice astragalus oral liquid or electuary or granule, its composite formula ratio is fermented glutinous rice nutrients or wine brewing nutritional product 5.0-9.8 part: Radix Astragali ethanol extract 0.1-3.0 part: especially formula rate is fermented glutinous rice nutrients or wine brewing nutritional product 7.5-9.0 part: most suitable during Radix Astragali ethanol extract 0.5-1.0 part;
Perhaps, be prepared into health products or medicine with conventional method; As being made into fermented glutinous rice Radix Astragali ass glue oral liquid or electuary or granule or pill, its composite formula ratio is fermented glutinous rice nutrients or wine brewing nutritional product 5.0-9.8 part: Radix Astragali ethanol extract 0.1-2.0 part: donkey-hide gelatin 0.1-3.0 part; Especially formula rate is fermented glutinous rice nutrients or wine brewing nutritional product 7.5-9.0 part: Radix Astragali ethanol extract 0.5-1.0: most suitable during donkey-hide gelatin 0.5-1.5 part;
Perhaps, be prepared into health products or medicine with conventional method; As being made into fermented glutinous rice glossy ganoderma fleece-flower root oral liquid or electuary or granule or pill, its composite formula ratio is fermented glutinous rice nutrients or wine brewing nutritional product 4.0-9.7 part: glossy ganoderma ethanol extract or water topic thing 0.1-2.0 part: Poria cocos ethanol extract or water topic thing 0.1-2.0 part: fleece-flower root ethanol extract or water extract 0.1-2.0 part; Especially formula rate is fermented glutinous rice nutrients or wine brewing nutritional product 7.0-9.7 part: glossy ganoderma ethanol extract or water extract 0.5-1.0: Poria cocos ethanol extract or water extract 0.1-1.0 part: most suitable when fleece-flower root ethanol extract or water extract 0.5-1.0 part;
Perhaps, be prepared into food, health products or medicine with conventional method; As being made into fermented glutinous rice kidney-tonifying and yang-strengthening oral solution or electuary or granule or pill, its composite formula ratio is fermented glutinous rice nutrients or wine brewing nutritional product 4.0-9.8 part: Chinese yam 0.1-2.0 part: pumpkin seeds benevolence 0.1-2.0 part; Fruit of Chinese wolfberry 0.5-2.0 part, especially formula rate is fermented glutinous rice nutrients or wine brewing nutritional product 7.0-9.0 part: Chinese yam 0.5-1.0 part: pumpkin seeds benevolence 0.2-1.0 part; Most suitable during fruit of Chinese wolfberry 0.3-1.0 part;
Perhaps, the purposes of the fermented glutinous rice nutrients of according to claim 1-8 any one or wine brewing nutritional product is: be used for bread and cheese, or be used for the treatment of leucocyte, red blood cell and thrombocytopenia, or promote health products and the medicine of leucocyte, red blood cell and platelet levels; Or can be used as adjuvant drug with tumour and cancer patient's radiotherapy, chemotherapy and surgical postoperative patient; Or can be used as be used for the treatment of men and women's sexual disorder and the requirement of raising property or improve health products and medicine sleep or that calm the nerves; Or be made into food, health products and the medicine that promotes infant development.
Perhaps, described fermented glutinous rice nutrients or wine brewing nutritional product are made the dosage form of various food or health products or medicine, comprise powder, pill, granule, electuary, tablet, oral liquid and liquid beverage, the preparation of solid beverage and pie shape, bar shaped and block shape; In case of necessity, the traditional auxiliary material that adds.
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| CN103932181A (en) * | 2014-04-04 | 2014-07-23 | 浙江省医学科学院 | Functional food for relieving pressure and improving memory and secondary fermentation preparation method thereof |
| CN103932179A (en) * | 2014-04-04 | 2014-07-23 | 浙江省医学科学院 | Health food for relieving stress and protecting liver and two-step fermentation preparation method of health food |
| CN103932180A (en) * | 2014-04-04 | 2014-07-23 | 浙江省医学科学院 | Pressure-relieving and anti-fatigue health-care food and two-step fermentation preparation method thereof |
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| CN105285258A (en) * | 2015-11-23 | 2016-02-03 | 黄宏荣 | Brown sugar vinasse tea production method |
| CN105685319A (en) * | 2016-03-01 | 2016-06-22 | 湖北省农业科学院农产品加工与核农技术研究所 | Method for preparing composite particle tea capable of being brewed repeatedly through fermentation with lotus seed macaroni |
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| CN103932179A (en) * | 2014-04-04 | 2014-07-23 | 浙江省医学科学院 | Health food for relieving stress and protecting liver and two-step fermentation preparation method of health food |
| CN103932180A (en) * | 2014-04-04 | 2014-07-23 | 浙江省医学科学院 | Pressure-relieving and anti-fatigue health-care food and two-step fermentation preparation method thereof |
| CN103932181B (en) * | 2014-04-04 | 2015-09-09 | 浙江省医学科学院 | A kind ofly to release the pressure and the functional food of Improving memory and two-step fermentation preparation method thereof |
| CN103932180B (en) * | 2014-04-04 | 2015-09-09 | 浙江省医学科学院 | A kind ofly to release the pressure and the health food of antifatigue and two-step fermentation preparation method thereof |
| CN103932179B (en) * | 2014-04-04 | 2015-09-09 | 浙江省医学科学院 | A kind of health food and two-step fermentation preparation method thereof releasing the pressure and protect liver |
| CN103999903A (en) * | 2014-05-04 | 2014-08-27 | 郎溪县百信精米厂 | Five-cereal healthy glutinous rice cake |
| CN106306676A (en) * | 2015-06-29 | 2017-01-11 | 桂林洁宇环保科技有限责任公司 | Lucid ganoderma and buckwheat health-care food having effects of preventing aging and prolonging life, and good mouthfeel |
| CN105285258A (en) * | 2015-11-23 | 2016-02-03 | 黄宏荣 | Brown sugar vinasse tea production method |
| CN105685319A (en) * | 2016-03-01 | 2016-06-22 | 湖北省农业科学院农产品加工与核农技术研究所 | Method for preparing composite particle tea capable of being brewed repeatedly through fermentation with lotus seed macaroni |
| CN105685319B (en) * | 2016-03-01 | 2019-06-18 | 湖北省农业科学院农产品加工与核农技术研究所 | Utilize the method for the composite particles tea that the fermentation preparation of lotus seeds macaroni can brew repeatedly |
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