CN110893169A - Whitening and moisturizing mask and preparation method thereof - Google Patents

Whitening and moisturizing mask and preparation method thereof Download PDF

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Publication number
CN110893169A
CN110893169A CN201911339714.4A CN201911339714A CN110893169A CN 110893169 A CN110893169 A CN 110893169A CN 201911339714 A CN201911339714 A CN 201911339714A CN 110893169 A CN110893169 A CN 110893169A
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parts
extract
ceramide
water
whitening
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CN110893169B (en
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廖文贵
杨述义
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Guangzhou Micro Peptide Biological Science And Technology Co Ltd
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Guangzhou Micro Peptide Biological Science And Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24Phosphorous; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/413Nanosized, i.e. having sizes below 100 nm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/524Preservatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Cosmetics (AREA)

Abstract

The invention belongs to the technical field of cosmetics, and provides a whitening and moisturizing mask and a preparation method thereof, wherein the whitening and moisturizing mask comprises the following components in parts by weight: 2-5 parts of arbutin, 0.7-1.5 parts of tranexamic acid, 0.8-1.5 parts of desert rose leaf cell extract, 1-3 parts of nicotinamide, 0.5-2 parts of glabrous licorice root extract, 5-20 parts of ceramide nanoemulsion, 1.7-3.5 parts of ascorbic acid, 1-5 parts of asiatic moonseed rhizome extract, 0.9-2.5 parts of towel gourd root extract, 0.5-2 parts of sweet violet extract, 0.1-0.3 part of polyphosphate double salt, 0.9-2.5 parts of polyacrylic acid, 0.1-0.5 part of butanediol, 0.9-2.5 parts of glycerol and 25-43 parts of water. The ceramide nanoemulsion consists of the following components in parts by weight: 1-5 parts of ceramide, 2-10 parts of olive oil, 5-15 parts of glycerol, 3-8 parts of castor oil polyoxyethylene ether, 1.5-4 parts of poloxamer and 35-62 parts of water. Through the technical scheme, the problems of poor ceramide dissolution and poor stability in the mask in the prior art are solved.

Description

Whitening and moisturizing mask and preparation method thereof
Technical Field
The invention belongs to the technical field of cosmetics, and relates to a whitening and moisturizing mask and a preparation method thereof.
Background
Among beauty cosmetics, facial masks are one of the earliest. The facial mask temporarily isolates outside air and pollution by using a short time of covering the facial mask, so that the temperature of the skin is increased, pores of the skin are expanded, the secretion and metabolism of sweat glands are promoted, the oxygen content of the skin is increased, products of metabolism of epidermal cells and accumulated grease substances are favorably discharged by the skin, water in the facial mask permeates into the horny layer of the epidermis of the skin, and the skin becomes soft. The skin is natural, bright and elastic.
Ceramides, also known as sphingolipids, are lipids present in the skin, play an important role in the formation of the stratum corneum of the epidermis, and are important roles in the physical barrier of the skin. Ceramides play the following important roles mainly in the stratum corneum of the skin: (1) ceramide is filled in the skin keratinocyte gap, so that water in the skin cannot permeate out, and excessive foreign matters cannot permeate into the skin, and the ceramide has a barrier protection function; (2) ceramides can maintain skin moisture by forming a network in the stratum corneum, which can prevent skin moisture loss; (3) ceramide has effects of improving symptoms such as facial dryness, flush, cosmetic infection, etc., and inhibiting melanin generation, and has obvious skin caring effect; (4) the ceramide skin care product can obviously thicken the horny layer of the skin, effectively inhibit skin allergy caused by the invasion of harmful substances and enhance the adaptability of the skin to the external environment. The ceramide is added into the facial mask as a raw material, so that the whitening and moisturizing effects of the facial mask can be improved, but in the actual production, the ceramide is poor in solubility and stability in the facial mask, and the effect of the ceramide is influenced. Therefore, the method for promoting the dissolution and the stability of the ceramide in the facial mask is provided, and the method has great significance in the field of cosmetics.
Disclosure of Invention
The invention provides a whitening and moisturizing mask and a preparation method thereof, and solves the problems of poor ceramide dissolution and poor stability in the mask in the prior art.
The technical scheme of the invention is realized as follows:
the whitening and moisturizing mask comprises the following components in parts by weight:
2-5 parts of arbutin, 0.7-1.5 parts of tranexamic acid, 0.8-1.5 parts of desert rose leaf cell extract, 1-3 parts of nicotinamide, 0.5-2 parts of glabrous licorice root extract, 5-20 parts of ceramide nanoemulsion, 1.7-3.5 parts of ascorbic acid, 1-5 parts of asiatic moonseed rhizome extract, 0.9-2.5 parts of towel gourd root extract, 0.5-2 parts of sweet violet extract, 0.1-0.3 part of polyphosphate double salt, 0.9-2.5 parts of polyacrylic acid, 0.1-0.5 part of butanediol, 0.9-2.5 parts of glycerol and 25-43 parts of water.
As a further technical scheme, the paint comprises the following components in parts by weight:
3 parts of arbutin, 1.2 parts of tranexamic acid, 1.2 parts of desert rose leaf cell extract, 2 parts of nicotinamide, 1.2 parts of glycyrrhiza glabra root extract, 13 parts of ceramide nanoemulsion, 2.6 parts of ascorbic acid, 3 parts of asiatic moonseed root extract, 1.6 parts of towel gourd root extract, 1.3 parts of herba violae extract, 0.2 part of polyphosphate double salt, 1.6 parts of polyacrylic acid, 0.3 part of butanediol, 1.7 parts of glycerol and 34 parts of water.
As a further technical scheme, the ceramide nanoemulsion consists of the following components in parts by weight:
1-5 parts of ceramide, 2-10 parts of olive oil, 5-15 parts of glycerol, 3-8 parts of castor oil polyoxyethylene ether, 1.5-4 parts of poloxamer and 35-62 parts of water.
As a further technical scheme, the ceramide nanoemulsion consists of the following components in parts by weight:
3 parts of ceramide, 6 parts of olive oil, 10 parts of glycerol, 5 parts of castor oil polyoxyethylene ether, 2.3 parts of poloxamer and 47 parts of water.
As a further technical scheme, the ceramide nanoemulsion is prepared by the following method: adding castor oil polyoxyethylene ether and glycerol into olive oil, mixing to obtain a mixed solution, adding ceramide into the mixed solution, stirring at 60 ℃ to obtain an oil phase, and cooling to room temperature;
dissolving poloxamer in water to obtain water phase;
and dropwise adding the water phase into the oil phase at the dropping speed of 1 drop/second, and stirring for 24 hours until a transparent system is formed to obtain the ceramide nanoemulsion.
As a further technical scheme, the preparation method of the glycyrrhiza glabra root extract comprises the following steps: pulverizing Glycyrrhrizae radix into coarse powder, heating and refluxing with ethanol, filtering, rotary evaporating the filtrate to remove ethanol, decocting with water, filtering, eluting the filtrate with ethyl acetate, concentrating, and drying to obtain Glycyrrhrizae radix extract; the preparation method of the Asiatic moonseed rhizome extract comprises the following steps: pulverizing rhizoma Menispermi into coarse powder, heating and refluxing with ethanol, filtering, rotary evaporating the filtrate to remove ethanol, decocting with water, filtering, eluting the filtrate with ethyl acetate, concentrating, and drying to obtain rhizoma Menispermi extract.
As a further technical scheme, the preparation method of the desert rose leaf cell extract comprises the following steps: pulverizing Rosa desertorum leaf into coarse powder, decocting in water, filtering, heating and concentrating the filtrate, eluting with ethanol, concentrating, and drying to obtain Rosa desertorum leaf cell extract;
the preparation method of the towel gourd root extract comprises the following steps: pulverizing radix Luffae into coarse powder, decocting with water, filtering, heating the filtrate, concentrating, eluting with ethanol, concentrating, and drying to obtain radix Luffae extract;
the preparation method of the herba corydalis Bungeanae extract comprises the following steps: decocting herba Violae powder with water, filtering, heating the filtrate, concentrating, eluting with ethanol, concentrating, and drying to obtain herba Violae extract.
The invention also provides a preparation method of the whitening and moisturizing mask, which comprises the following steps:
s1, weighing the components according to the formula of the whitening and moisturizing mask for later use;
s2, mixing a desert rose leaf cell extract, a glabrous greenbrier rhizome extract, a asiatic moonseed rhizome extract, a towel gourd root extract and a sweet violet extract, adding the mixture into ceramide nanoemulsion, stirring and heating to 66-68 ℃, and homogenizing and dispersing uniformly to obtain a first primary mixed material;
s3, mixing butanediol and glycerol, heating to 66-68 ℃, and uniformly stirring and dissolving to obtain a primary mixed material II;
s4, adding the first primary mixed material obtained in the step S3 into the first primary mixed material obtained in the step S2 in a stirring state, and uniformly stirring to obtain a first mixed solution;
s5, adding polyacrylic acid into water, sequentially adding arbutin, tranexamic acid, ascorbic acid and nicotinamide, and uniformly mixing to obtain a second mixed solution;
s6, adding the first mixed solution obtained in the step S4 into the second mixed solution obtained in the step S5, uniformly mixing, adding polyphosphate double salt, and uniformly mixing to obtain the whitening and moisturizing mask.
The working principle and the beneficial effects of the invention are as follows:
1. according to the invention, the prepared mask has good whitening effect, melanin generation inhibition, skin texture improvement and skin metabolism promotion, and also has good moisturizing effect, and the prepared mask has good storage stability, is safe and reliable, and is suitable for popularization and use, and can relieve skin dryness, lock skin moisture and prevent volatilization of skin surface moisture.
2. According to the invention, the compound phosphate double salt in the mask raw material is compatible with the glycyrrhiza glabra root extract, the asiatic moonseed rhizome extract and the sweet violet extract, so that the growth of bacteria, mould, saccharomycetes and other microorganisms in the mask can be inhibited, and the storage stability of the mask liquid is improved, so that the prepared mask is safe and reliable, and is suitable for popularization and use.
3. According to the invention, the oil-in-water technology is adopted to prepare the ceramide into the nanoemulsion, and then the ceramide nanoemulsion is used as a raw material to prepare the facial mask, so that the solubility and the stability of the ceramide in the facial mask are obviously improved, the exertion of the ceramide effect in the facial mask is effectively promoted, and the whitening effect of the facial mask is further improved. The glycyrrhiza glabra root extract, the asiatic moonseed rhizome extract and the herba violae extract are mutually compatible, so that the activity of various enzymes in the melanin generation process can be effectively inhibited, and the whitening effect of the mask is further improved. When the ceramide nanoemulsion is singly used, and the glycyrrhiza glabra root extract, the asiatic moonseed rhizome extract and the herba violae extract are singly used, the good whitening effect cannot be achieved, and the ceramide nanoemulsion, the glycyrrhiza glabra root extract, the asiatic moonseed rhizome extract and the herba violae extract are mutually compatible, so that the whitening effect of the mask can be remarkably improved.
4. According to the invention, the ceramide nanoemulsion in the mask raw material interacts with the polyphosphoric acid complex salt and polyacrylic acid, so that the moisturizing effect of the mask liquid is obviously improved. Polyacrylic acid and polyphosphate are mutually compatible and can form a hydrated adhesive film when being used on the surface of skin, a moisturizing environment is provided for the skin, the dryness of the skin is relieved, on the basis, the ceramide nanoemulsion locks the moisture of the skin and prevents the volatilization of the moisture on the surface of the skin, and the three components are mutually compatible, so that the good water replenishing and moisturizing effects are achieved.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The whitening and moisturizing mask comprises the following components in parts by weight:
2 parts of arbutin, 0.7 part of tranexamic acid, 0.8 part of desert rose leaf cell extract, 1 part of nicotinamide, 0.5 part of glycyrrhiza glabra root extract, 5 parts of ceramide nanoemulsion, 1.7 parts of ascorbic acid, 1 part of asiatic moonseed root extract, 0.9 part of towel gourd root extract, 0.5 part of herba violae extract, 0.1-0.3 part of polyphosphate double salt, 0.9 part of polyacrylic acid, 0.1 part of butanediol, 0.9 part of glycerol and 25 parts of water,
the ceramide nanoemulsion is prepared by the following method: adding 5 parts of castor oil polyoxyethylene ether and 10 parts of glycerol into 6 parts of olive oil, uniformly mixing to obtain a mixed solution, adding 3 parts of ceramide into the mixed solution, uniformly stirring at 60 ℃ to obtain an oil phase, and cooling to room temperature; dissolving 2.3 parts of poloxamer in 47 parts of water to obtain a water phase; dropwise adding the water phase into the oil phase at a dropping speed of 1 drop/second, and stirring for 24 hours until a transparent system is formed to obtain the ceramide nanoemulsion;
the preparation method comprises the following steps:
s1, weighing the components according to the formula for later use;
s2, mixing a desert rose leaf cell extract, a glabrous greenbrier rhizome extract, a asiatic moonseed rhizome extract, a towel gourd root extract and a sweet violet extract, adding the mixture into ceramide nanoemulsion, stirring and heating to 66-68 ℃, and homogenizing and dispersing uniformly to obtain a first primary mixed material;
s3, mixing butanediol and glycerol, heating to 66-68 ℃, and uniformly stirring and dissolving to obtain a primary mixed material II;
s4, adding the first primary mixed material obtained in the step S3 into the first primary mixed material obtained in the step S2 in a stirring state, and uniformly stirring to obtain a first mixed solution;
s5, adding polyacrylic acid into water, sequentially adding arbutin, tranexamic acid, ascorbic acid and nicotinamide, and uniformly mixing to obtain a second mixed solution;
s6, adding the first mixed solution obtained in the step S4 into the second mixed solution obtained in the step S5, uniformly mixing, adding polyphosphate double salt, and uniformly mixing to obtain the whitening and moisturizing mask.
Example 2
The whitening and moisturizing mask comprises the following components in parts by weight:
5 parts of arbutin, 1.5 parts of tranexamic acid, 1.5 parts of desert rose leaf cell extract, 3 parts of nicotinamide, 2 parts of glycyrrhiza glabra root extract, 20 parts of ceramide nanoemulsion, 3.5 parts of ascorbic acid, 5 parts of asiatic moonseed root extract, 2.5 parts of towel gourd root extract, 2 parts of herba violae extract, 0.3 part of polyphosphate double salt, 2.5 parts of polyacrylic acid, 0.5 part of butanediol, 2.5 parts of glycerol and 43 parts of water,
the ceramide nanoemulsion is prepared by the following method: adding 5 parts of castor oil polyoxyethylene ether and 10 parts of glycerol into 6 parts of olive oil, uniformly mixing to obtain a mixed solution, adding 3 parts of ceramide into the mixed solution, uniformly stirring at 60 ℃ to obtain an oil phase, and cooling to room temperature; dissolving 2.3 parts of poloxamer in 47 parts of water to obtain a water phase; dropwise adding the water phase into the oil phase at a dropping speed of 1 drop/second, and stirring for 24 hours until a transparent system is formed to obtain the ceramide nanoemulsion;
the preparation method is the same as that of example 1.
Example 3
The whitening and moisturizing mask comprises the following components in parts by weight:
3 parts of arbutin, 1.3 parts of tranexamic acid, 1 part of desert rose leaf cell extract, 2.5 parts of nicotinamide, 1 part of glycyrrhiza glabra root extract, 10 parts of ceramide nanoemulsion, 3.2 parts of ascorbic acid, 4 parts of asiatic moonseed root extract, 2.2 parts of towel gourd root extract, 1 part of herba violae extract, 0.25 part of polyphosphate double salt, 2.1 parts of polyacrylic acid, 0.4 part of butanediol, 1.3 parts of glycerol and 38 parts of water,
the ceramide nanoemulsion is prepared by the following method: adding 5 parts of castor oil polyoxyethylene ether and 10 parts of glycerol into 6 parts of olive oil, uniformly mixing to obtain a mixed solution, adding 3 parts of ceramide into the mixed solution, uniformly stirring at 60 ℃ to obtain an oil phase, and cooling to room temperature; dissolving 2.3 parts of poloxamer in 47 parts of water to obtain a water phase; dropwise adding the water phase into the oil phase at a dropping speed of 1 drop/second, and stirring for 24 hours until a transparent system is formed to obtain the ceramide nanoemulsion;
the preparation method is the same as that of example 1.
Example 4
The whitening and moisturizing mask comprises the following components in parts by weight:
4 parts of arbutin, 0.9 part of tranexamic acid, 1.3 parts of desert rose leaf cell extract, 1.5 parts of nicotinamide, 1.5 parts of glycyrrhiza glabra root extract, 15 parts of ceramide nanoemulsion, 2.1 parts of ascorbic acid, 2 parts of asiatic moonseed root extract, 1.3 parts of towel gourd root extract, 1.6 parts of herba violae extract, 0.15 part of polyphosphate double salt, 1.3 parts of polyacrylic acid, 0.2 part of butanediol, 2.1 parts of glycerol and 30 parts of water,
the ceramide nanoemulsion is prepared by the following method: adding 5 parts of castor oil polyoxyethylene ether and 10 parts of glycerol into 6 parts of olive oil, uniformly mixing to obtain a mixed solution, adding 3 parts of ceramide into the mixed solution, uniformly stirring at 60 ℃ to obtain an oil phase, and cooling to room temperature; dissolving 2.3 parts of poloxamer in 47 parts of water to obtain a water phase; dropwise adding the water phase into the oil phase at a dropping speed of 1 drop/second, and stirring for 24 hours until a transparent system is formed to obtain the ceramide nanoemulsion;
the preparation method is the same as that of example 1.
Example 5
The whitening and moisturizing mask comprises the following components in parts by weight:
3 parts of arbutin, 1.2 parts of tranexamic acid, 1.2 parts of desert rose leaf cell extract, 2 parts of nicotinamide, 1.2 parts of glycyrrhiza glabra root extract, 13 parts of ceramide nanoemulsion, 2.6 parts of ascorbic acid, 3 parts of asiatic moonseed root extract, 1.6 parts of towel gourd root extract, 1.3 parts of herba violae extract, 0.2 part of polyphosphate double salt, 1.6 parts of polyacrylic acid, 0.3 part of butanediol, 1.7 parts of glycerol and 34 parts of water,
the ceramide nanoemulsion is prepared by the following method: adding 5 parts of castor oil polyoxyethylene ether and 10 parts of glycerol into 6 parts of olive oil, uniformly mixing to obtain a mixed solution, adding 3 parts of ceramide into the mixed solution, uniformly stirring at 60 ℃ to obtain an oil phase, and cooling to room temperature; dissolving 2.3 parts of poloxamer in 47 parts of water to obtain a water phase; dropwise adding the water phase into the oil phase at a dropping speed of 1 drop/second, and stirring for 24 hours until a transparent system is formed to obtain the ceramide nanoemulsion;
the preparation method is the same as that of example 1.
Example 6
The whitening and moisturizing mask comprises the following components in parts by weight:
3 parts of arbutin, 1.2 parts of tranexamic acid, 1.2 parts of desert rose leaf cell extract, 2 parts of nicotinamide, 1.2 parts of glycyrrhiza glabra root extract, 13 parts of ceramide nanoemulsion, 2.6 parts of ascorbic acid, 3 parts of asiatic moonseed root extract, 1.6 parts of towel gourd root extract, 1.3 parts of herba violae extract, 0.2 part of polyphosphate double salt, 1.6 parts of polyacrylic acid, 0.3 part of butanediol, 1.7 parts of glycerol and 34 parts of water,
the ceramide nanoemulsion is prepared by the following method: adding 3 parts of castor oil polyoxyethylene ether and 5 parts of glycerol into 2 parts of olive oil, uniformly mixing to obtain a mixed solution, adding 1 part of ceramide into the mixed solution, uniformly stirring at 60 ℃ to obtain an oil phase, and cooling to room temperature; dissolving 1.5 parts of poloxamer in 35 parts of water to obtain a water phase; dropwise adding the water phase into the oil phase at a dropping speed of 1 drop/second, and stirring for 24 hours until a transparent system is formed to obtain the ceramide nanoemulsion;
the preparation method is the same as that of example 1.
Example 7
The whitening and moisturizing mask comprises the following components in parts by weight:
3 parts of arbutin, 1.2 parts of tranexamic acid, 1.2 parts of desert rose leaf cell extract, 2 parts of nicotinamide, 1.2 parts of glycyrrhiza glabra root extract, 13 parts of ceramide nanoemulsion, 2.6 parts of ascorbic acid, 3 parts of asiatic moonseed root extract, 1.6 parts of towel gourd root extract, 1.3 parts of herba violae extract, 0.2 part of polyphosphate double salt, 1.6 parts of polyacrylic acid, 0.3 part of butanediol, 1.7 parts of glycerol and 34 parts of water,
the ceramide nanoemulsion is prepared by the following method: adding 8 parts of castor oil polyoxyethylene ether and 15 parts of glycerol into 10 parts of olive oil, uniformly mixing to obtain a mixed solution, adding 5 parts of ceramide into the mixed solution, uniformly stirring at 60 ℃ to obtain an oil phase, and cooling to room temperature; dissolving 4 parts of poloxamer in 62 parts of water to obtain a water phase; dropwise adding the water phase into the oil phase at a dropping speed of 1 drop/second, and stirring for 24 hours until a transparent system is formed to obtain the ceramide nanoemulsion;
the preparation method is the same as that of example 1.
Comparative example 1
The whitening and moisturizing mask comprises the following components in parts by weight:
3 parts of arbutin, 1.2 parts of tranexamic acid, 1.2 parts of desert rose leaf cell extract, 2 parts of nicotinamide, 1.2 parts of glycyrrhiza glabra root extract, 13 parts of ceramide, 2.6 parts of ascorbic acid, 3 parts of asiatic moonseed root extract, 1.6 parts of towel gourd root extract, 1.3 parts of herba violae extract, 0.2 part of polyphosphate double salt, 1.6 parts of polyacrylic acid, 0.3 part of butanediol, 1.7 parts of glycerol and 34 parts of water,
the corresponding step S2 in the preparation method is: mixing the desert rose leaf cell extract, the glycyrrhiza glabra root extract, the asiatic moonseed rhizome extract, the towel gourd root extract and the sweet violet extract, adding the mixture into ceramide, stirring and heating to 66-68 ℃, and homogenizing and dispersing uniformly to obtain a first primary mixed material; the rest of the procedure was the same as in example 1.
Comparative example 2
The whitening and moisturizing mask comprises the following components in parts by weight:
3 parts of arbutin, 1.2 parts of tranexamic acid, 1.2 parts of desert rose leaf cell extract, 2 parts of nicotinamide, 1.2 parts of glycyrrhiza glabra root extract, 13 parts of ceramide nanoemulsion, 2.6 parts of ascorbic acid, 3 parts of asiatic moonseed root extract, 1.6 parts of towel gourd root extract, 1.3 parts of herba violae extract, 0.3 part of butanediol, 1.7 parts of glycerol and 34 parts of water,
the ceramide nanoemulsion is prepared by the following method: adding 5 parts of castor oil polyoxyethylene ether and 10 parts of glycerol into 6 parts of olive oil, uniformly mixing to obtain a mixed solution, adding 3 parts of ceramide into the mixed solution, uniformly stirring at 60 ℃ to obtain an oil phase, and cooling to room temperature; dissolving 2.3 parts of poloxamer in 47 parts of water to obtain a water phase; dropwise adding the water phase into the oil phase at a dropping speed of 1 drop/second, and stirring for 24 hours until a transparent system is formed to obtain the ceramide nanoemulsion;
the preparation method is the same as that of example 1 except that no polyphosphate double salt and polyacrylic acid are added in step S6.
Comparative example 3
The whitening and moisturizing mask comprises the following components in parts by weight:
3 parts of arbutin, 1.2 parts of tranexamic acid, 1.2 parts of desert rose leaf cell extract, 2 parts of nicotinamide, 13 parts of ceramide nanoemulsion, 2.6 parts of ascorbic acid, 1.6 parts of towel gourd root extract, 0.2 part of polyphosphate complex salt, 1.6 parts of polyacrylic acid, 0.3 part of butanediol, 1.7 parts of glycerol and 34 parts of water,
the ceramide nanoemulsion is prepared by the following method: adding 5 parts of castor oil polyoxyethylene ether and 10 parts of glycerol into 6 parts of olive oil, uniformly mixing to obtain a mixed solution, adding 3 parts of ceramide into the mixed solution, uniformly stirring at 60 ℃ to obtain an oil phase, and cooling to room temperature; dissolving 2.3 parts of poloxamer in 47 parts of water to obtain a water phase; dropwise adding the water phase into the oil phase at a dropping speed of 1 drop/second, and stirring for 24 hours until a transparent system is formed to obtain the ceramide nanoemulsion;
the preparation method is the same as that of example 1 except that the glycyrrhiza glabra root extract, the asiatic moonseed rhizome extract and the herba violae extract are not added in step S2.
In examples 1 to 7 and comparative examples 1 to 3,
the preparation method of the glycyrrhiza glabra root extract comprises the following steps: pulverizing Glycyrrhrizae radix into coarse powder, heating and refluxing with ethanol, filtering, rotary evaporating the filtrate to remove ethanol, decocting with water, filtering, eluting the filtrate with ethyl acetate, concentrating, and drying to obtain Glycyrrhrizae radix extract;
the preparation method of the Asiatic moonseed rhizome extract comprises the following steps: pulverizing rhizoma Menispermi into coarse powder, heating and refluxing with ethanol, filtering, rotary evaporating the filtrate to remove ethanol, decocting with water, filtering, eluting the filtrate with ethyl acetate, concentrating, and drying to obtain rhizoma Menispermi extract;
the preparation method of the desert rose leaf cell extract comprises the following steps: pulverizing Rosa desertorum leaf into coarse powder, decocting in water, filtering, heating and concentrating the filtrate, eluting with ethanol, concentrating, and drying to obtain Rosa desertorum leaf cell extract;
the preparation method of the towel gourd root extract comprises the following steps: pulverizing radix Luffae into coarse powder, decocting with water, filtering, heating the filtrate, concentrating, eluting with ethanol, concentrating, and drying to obtain radix Luffae extract;
the preparation method of the herba corydalis Bungeanae extract comprises the following steps: decocting herba Violae powder with water, filtering, heating the filtrate, concentrating, eluting with ethanol, concentrating, and drying to obtain herba Violae extract.
The following performance tests were performed on the masks prepared in examples 1 to 7 and comparative examples 1 to 3:
1. and (3) microbial detection: items such as total bacteria, total mold/yeast, heat-resistant coliform group, staphylococcus aureus and pseudomonas aeruginosa in the mask samples prepared in examples 1 to 7 and comparative examples 1 to 3 and the samples stored for 30 days were detected according to the method specified in technical specification for cosmetic safety (2015), and the detection results are shown in the following table:
TABLE 1 results of microbiological examination of masks prepared in examples 1 to 7 and comparative examples 1 to 3
Figure BDA0002331930130000081
TABLE 2 microbial test results of masks prepared in examples 1 to 7 and comparative examples 1 to 3
Figure BDA0002331930130000091
As can be seen from the data in table 2, the total number of bacteria in the mask products of examples 1 to 7 and comparative examples 1 to 3 is less than 10/mL, the total number of mold/yeast is less than 10/mL, and heat-resistant coliform group, staphylococcus aureus and pseudomonas aeruginosa are not detected, and meanwhile, the total number of bacteria, mold/yeast, heat-resistant coliform group, staphylococcus aureus and pseudomonas aeruginosa in the samples of the masks of examples 1 to 7 after being stored for 30 days are not changed, and the results of microbial examination show that the masks meet the requirements of technical cosmetic safety standards (2015 edition), which indicates that the masks prepared by the invention are safe and reliable. .
Compared with the mask solutions of examples 1 to 7, the total number of bacteria and the total number of mold/yeast of the mask of comparative examples 2 to 3 are increased in a sample after the mask solution is stored for 30 days, so that microorganisms are easily bred in the mask of comparative examples 2 to 3 in the storage process, and the storage is unstable, because polyphosphoric acid complex salt and polyacrylic acid are not added in the formula of the mask of comparative example 2, and glycyrrhiza glabra root extract, asiatic moonseed rhizome extract and herba violae extract are not added in the formula of the mask solution of comparative example 3, which indicates that polyphosphoric acid complex salt, polyacrylic acid, glycyrrhiza glabra root extract, asiatic moonseed rhizome extract and herba violae extract are compatible with each other, so that the growth of microorganisms such as bacteria, mold and yeast in the mask solution can be inhibited, the storage stability of the mask solution is improved, and the prepared mask solution is safe and reliable and is.
2. Selecting 100 female volunteers, wherein the female volunteers are 25-35 years old and randomly divided into 10 groups, each group comprises 10 individuals, measuring the brightness of the facial skin by a colorimeter, marking as L1, using the facial masks of examples 1-7 and comparative examples 1-3 respectively for each group, coating the facial masks on the whole face twice each day when in use, measuring the brightness of the facial skin by the colorimeter after coating for 4 weeks, marking as L2, calculating the color difference of the brightness of the facial skin after the facial masks of the examples and comparative examples are used, marking as △ L, and marking as L2-L1 for △ L, so as to evaluate the whitening effect of the facial masks of the examples and comparative examples, wherein when △ L is more than or equal to 2, the pigmentation is obviously relieved, and the whitening effect is achieved, and the test results are shown in the following table:
TABLE 3 whitening efficacy of masks prepared in examples 1 to 7 and comparative examples 1 to 3
Group of ΔL
Example 1 4.26
Example 2 4.35
Example 3 4.32
Example 4 4.47
Example 5 4.55
Example 6 4.38
Example 7 4.43
Comparative example 1 0.39
Comparative example 2 3.72
Comparative example 3 0.58
As can be seen from table 3, after the mask products of embodiments 1 to 7 of the present invention are used for 4 weeks, the chromaticity difference of the facial skin of the volunteers reaches 4.26 or more, which indicates that the mask products of embodiments 1 to 7 of the present invention can significantly improve the pigmentation of the facial skin, and have a good whitening effect.
Compared with the masks of examples 1 to 7, the mask products of comparative examples 1 and 3 have poor whitening effect, because the ceramide is added into the mask raw material of comparative example 1, and the ceramide nanoemulsion is not added, and the glabrous greenbrier rhizome extract, the asiatic moonseed rhizome extract and the herba violae extract are not added into the mask product of comparative example 3, which shows that the whitening effect of the mask can be remarkably improved by adding the ceramide nanoemulsion, the glabrous greenbrier rhizome extract, the asiatic moonseed rhizome extract and the herba violae extract into the mask product. Ceramide can inhibit melanin generation, promote skin metabolism, promote the exfoliation of melanin-containing keratinocytes, promote the synthesis of surface proteins, and improve skin texture, but ceramide has poor solubility and stability in facial masks, which affects the efficacy. The oil-in-water technology is adopted to prepare the ceramide into the nanoemulsion, and then the ceramide nanoemulsion is used as a raw material to prepare the mask, so that the solubility and the stability of the ceramide in the mask are remarkably improved, the exertion of the effect of the ceramide in the mask is effectively promoted, and the whitening effect of the mask is improved. The glycyrrhiza glabra root extract, the asiatic moonseed rhizome extract and the herba violae extract are mutually compatible, so that the activity of various enzymes in the melanin generation process can be effectively inhibited, and the whitening effect of the mask is further improved. It can be seen from the results of comparative examples 1 and 3 that the good whitening effect can not be achieved by using the ceramide nanoemulsion alone and using the glycyrrhiza glabra root extract, the asiatic moonseed rhizome extract and the herba violae extract alone, so that the whitening effect of the mask can be remarkably improved only by mutually matching the ceramide nanoemulsion with the glycyrrhiza glabra root extract, the asiatic moonseed rhizome extract and the herba violae extract.
3. Moisturizing effect: the moisture content of the skin stratum corneum is measured according to a capacitance method specified in QB/T4256-2011 'guidelines for evaluating moisturizing effects of cosmetics'. During testing, 100 female volunteers are selected, the female volunteers are 25-35 years old and randomly divided into 10 groups, 10 persons in each group are detected, the positions of the detected persons are the inner sides of the forearms of the two hands of the detected persons, a use area and a blank control area are divided before use, the facial masks prepared in the embodiments 1-7 and the comparative examples 1-3 are respectively used in the use areas of all groups, the blank control group is not treated, the moisture content of the stratum corneum is respectively tested on the use areas and the blank control areas by using a skin moisture tester before use and after use for 4 hours, and the test results are shown in a table 4:
TABLE 4 moisture retention test results of the masks of examples 1 to 7 and comparative examples 1 to 3
Group of Moisture increment value (%)
Blank control group 0
Example 1 11.6
Example 2 11.3
Example 3 12.2
Example 4 12.3
Example 5 12.8
Example 6 12.4
Example 7 12.2
Comparative example 1 3.6
Comparative example 2 5.8
Comparative example 3 10.7
The data in table 4 show that after the facial masks of examples 1 to 7 are used for 4 hours, the moisture increase of the skin stratum corneum is remarkably improved, and the moisture increase value is as high as 13.7%, which indicates that the facial masks prepared in examples 1 to 7 have good moisturizing and moisturizing effects and meet the use requirements of consumers.
Compared with the facial masks of examples 1-7, the moisture value of the stratum corneum of the skin after 4 hours of using the facial mask liquid of comparative examples 1-2 is slightly increased, because the ceramide is added into the raw material of the facial mask of comparative example 1, the ceramide nanoemulsion is not added, and the polyphosphoric acid complex salt and polyacrylic acid are not added into the facial mask product of comparative example 2, which shows that the ceramide nanoemulsion, the polyphosphoric acid complex salt and the polyacrylic acid interact with each other, and the moisturizing effect of the facial mask liquid is obviously improved. Polyacrylic acid and polyphosphate are mutually compatible and can form a hydrated adhesive film when being used on the surface of skin, a moisturizing environment is provided for the skin, the dryness of the skin is relieved, on the basis, the ceramide nanoemulsion locks the moisture of the skin and prevents the volatilization of the moisture on the surface of the skin, and the three components are mutually compatible, so that the good water replenishing and moisturizing effects are achieved.
The present invention is not limited to the above preferred embodiments, and any modifications, equivalent substitutions, improvements, etc. within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (8)

1. The whitening and moisturizing mask is characterized by comprising the following components in parts by weight:
2-5 parts of arbutin, 0.7-1.5 parts of tranexamic acid, 0.8-1.5 parts of desert rose leaf cell extract, 1-3 parts of nicotinamide, 0.5-2 parts of glabrous licorice root extract, 5-20 parts of ceramide nanoemulsion, 1.7-3.5 parts of ascorbic acid, 1-5 parts of asiatic moonseed rhizome extract, 0.9-2.5 parts of towel gourd root extract, 0.5-2 parts of sweet violet extract, 0.1-0.3 part of polyphosphate double salt, 0.9-2.5 parts of polyacrylic acid, 0.1-0.5 part of butanediol, 0.9-2.5 parts of glycerol and 25-43 parts of water.
2. The whitening and moisturizing mask as claimed in claim 1, which is characterized by comprising the following components in parts by weight:
3 parts of arbutin, 1.2 parts of tranexamic acid, 1.2 parts of desert rose leaf cell extract, 2 parts of nicotinamide, 1.2 parts of glycyrrhiza glabra root extract, 13 parts of ceramide nanoemulsion, 2.6 parts of ascorbic acid, 3 parts of asiatic moonseed root extract, 1.6 parts of towel gourd root extract, 1.3 parts of herba violae extract, 0.2 part of polyphosphate double salt, 1.6 parts of polyacrylic acid, 0.3 part of butanediol, 1.7 parts of glycerol and 34 parts of water.
3. The whitening and moisturizing mask as claimed in claim 1 or 2, wherein the ceramide nanoemulsion consists of the following components in parts by weight:
1-5 parts of ceramide, 2-10 parts of olive oil, 5-15 parts of glycerol, 3-8 parts of castor oil polyoxyethylene ether, 1.5-4 parts of poloxamer and 35-62 parts of water.
4. The whitening and moisturizing mask as claimed in claim 3, wherein the ceramide nanoemulsion consists of the following components in parts by weight:
3 parts of ceramide, 6 parts of olive oil, 10 parts of glycerol, 5 parts of castor oil polyoxyethylene ether, 2.3 parts of poloxamer and 47 parts of water.
5. The whitening and moisturizing mask as claimed in claim 4, wherein the ceramide nanoemulsion is prepared by the following method: adding castor oil polyoxyethylene ether and glycerol into olive oil, mixing to obtain a mixed solution, adding ceramide into the mixed solution, stirring at 60 ℃ to obtain an oil phase, and cooling to room temperature;
dissolving poloxamer in water to obtain water phase;
and dropwise adding the water phase into the oil phase at the dropping speed of 1 drop/second, and stirring for 24 hours until a transparent system is formed to obtain the ceramide nanoemulsion.
6. The whitening and moisturizing mask as claimed in claim 1, wherein the glycyrrhiza glabra root extract is prepared by the following method: pulverizing Glycyrrhrizae radix into coarse powder, heating and refluxing with ethanol, filtering, rotary evaporating the filtrate to remove ethanol, decocting with water, filtering, eluting the filtrate with ethyl acetate, concentrating, and drying to obtain Glycyrrhrizae radix extract; the preparation method of the Asiatic moonseed rhizome extract comprises the following steps: pulverizing rhizoma Menispermi into coarse powder, heating and refluxing with ethanol, filtering, rotary evaporating the filtrate to remove ethanol, decocting with water, filtering, eluting the filtrate with ethyl acetate, concentrating, and drying to obtain rhizoma Menispermi extract.
7. The whitening and moisturizing mask as claimed in claim 1, wherein the preparation method of the desert rose leaf cell extract is as follows: pulverizing Rosa desertorum leaf into coarse powder, decocting in water, filtering, heating and concentrating the filtrate, eluting with ethanol, concentrating, and drying to obtain Rosa desertorum leaf cell extract;
the preparation method of the towel gourd root extract comprises the following steps: pulverizing radix Luffae into coarse powder, decocting with water, filtering, heating the filtrate, concentrating, eluting with ethanol, concentrating, and drying to obtain radix Luffae extract;
the preparation method of the herba corydalis Bungeanae extract comprises the following steps: decocting herba Violae powder with water, filtering, heating the filtrate, concentrating, eluting with ethanol, concentrating, and drying to obtain herba Violae extract.
8. The preparation method of the whitening and moisturizing mask is characterized by comprising the following steps:
s1, weighing all components for later use according to the formula of the whitening and moisturizing mask as claimed in any one of claims 1 to 7;
s2, mixing a desert rose leaf cell extract, a glabrous greenbrier rhizome extract, a asiatic moonseed rhizome extract, a towel gourd root extract and a sweet violet extract, adding the mixture into ceramide nanoemulsion, stirring and heating to 66-68 ℃, and homogenizing and dispersing uniformly to obtain a first primary mixed material;
s3, mixing butanediol and glycerol, heating to 66-68 ℃, and uniformly stirring and dissolving to obtain a primary mixed material II;
s4, adding the first primary mixed material obtained in the step S3 into the first primary mixed material obtained in the step S2 in a stirring state, and uniformly stirring to obtain a first mixed solution;
s5, adding polyacrylic acid into water, sequentially adding arbutin, tranexamic acid, ascorbic acid and nicotinamide, and uniformly mixing to obtain a second mixed solution;
s6, adding the first mixed solution obtained in the step S4 into the second mixed solution obtained in the step S5, uniformly mixing, adding polyphosphate double salt, and uniformly mixing to obtain the whitening and moisturizing mask.
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