CN107213063A - A kind of fair-skinned bright fine flour film and preparation method thereof - Google Patents
A kind of fair-skinned bright fine flour film and preparation method thereof Download PDFInfo
- Publication number
- CN107213063A CN107213063A CN201710424386.2A CN201710424386A CN107213063A CN 107213063 A CN107213063 A CN 107213063A CN 201710424386 A CN201710424386 A CN 201710424386A CN 107213063 A CN107213063 A CN 107213063A
- Authority
- CN
- China
- Prior art keywords
- fair
- fine flour
- bright fine
- flour film
- skinned bright
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Abstract
The invention belongs to cosmetic technical field, and in particular to a kind of fair-skinned bright fine flour film and preparation method thereof.The fair-skinned bright fine flour film that the present invention is provided includes propane diols, ethoxy urea, glycine betaine, 3 O ethylascorbyls, ursin, purslane extract, thyme extract, tree peony whitening elite, panthenol, niacinamide, the esters of Jojoba wax PEG 120, tranexamic acid, carbomer, triethanolamine, Sodium Hyaluronate, the rilanit specials of PEG 40, methyl hydroxybenzoate, Phenoxyethanol/Sensiva SC50, parahydroxyacet-ophenone, essence and water.The fair-skinned bright fine flour film that the present invention is provided, its natural safety, contains various active composition, good penetrability can go deep into flesh bottom and largely keep the skin wet and nutrient, replenishing water and preserving moisture, nourishes maintenance, and skin whitening, dispelling stain improves the dark yellow state of skin, recovered pale penetrating.
Description
Technical field
The invention belongs to cosmetic technical field, and in particular to a kind of fair-skinned bright fine flour film and preparation method thereof.
Background technology
In recent years, with the raising of people's living standard and aesthetical standard, increasing people pursues, thirsts for pale and clean
The skin of profit.Therefore, with prevent the color spot as caused by sunray and other reasons, pigmentation whitening class make up
The research and development of product and skin-whitening preparation, are just being increasingly subject to various countries' cosmetic Manufacture business and the attention of researcher, whitening
Cosmetics turn into one of main flow kind of skin-care cosmetics.
The effect of whitening product is mainly by suppressing tyrosinase activity or blocking the oxygen of tyrosine generation melanin
Change approach, so as to reduce the effect that melanin generation reaches skin whitening.Skin-whitening product is exactly to act on dermal melanin
In generation, metabolic process, suppress melanin generation and meet the material of specification.But, traditional skin-whitening agents are often used
Chemical substance, such as has the mercury salt of whitening effect and the quinhydrones of effect of dispelling spots.Although these compounds are rapidly achieved whitening
The effect of, but to skin toxic side effect, long-term use can cause contact dermatitis or cause the ill-effects such as permanent decolouring,
Many countries are disabled.The skin-whitening agents currently required that should comply with two standards：One be have to tyrosinase activity compared with
High inhibiting rate, can significantly reduce the generation of melanin；Two be to have higher security, nontoxic non-stimulated with human body skin.
Ursin, VitC derivatives and kojic acid are the whitening compositions more often used in skin-lightening cosmetic both at home and abroad at present.In order to develop symbol
The cosmetics that " going back to nature " requires, particularly safety, the whitening product having no side effect are closed, some have fine whitening effect
Natural plant composition increasingly favored at present by consumer.Find exploitation efficiently and human body is had no side effect or side effect
Small natural plants skin-whitening and speckle eliminating preparation is as one of the current cosmetic field problem being relatively taken seriously.
Chinese patent application CN103494760A discloses a kind of moistening and whitening facial mask, and the gross mass relative to facial mask liquid contains
There is following components：Bar horse mineral water 75%~80%, asparagus juice 3%~7%, rose extract 1%~3%, egg white 1%~
3%th, hydrolyzed pearl 0.5%~2%, green cucumber extract solution 1%~2%, pomegranate extract solution 2%~5%.
Chinese patent application CN105832600A discloses the raw material in a kind of emblic moistening and whitening facial mask patch, its formula
And weight ratio is respectively：0.5 part of emblic, 10 parts of aloe, 2 parts of propane diols, 2 parts of glycerine, 3 parts of hyaluronic acid, 10 parts of the hydrosol,
Preservative qs, appropriate essence, deionized water add to 100 parts.
Chinese patent application CN104958238A discloses a kind of cleawhite pack, including following parts by weight raw material：Hydrolysis
30-50 parts of collagen, 20-30 parts of milk elite, 10-20 parts of olive oil, 30-50 parts of glycerine, 10-20 parts of vitamin C, green tea
5-10 parts of elite.
Whitening is also a nursing engineering from inside to outside.The a set of suitable whitening product of oneself of selection is first had to, because
Whitening composition is different, so can so prevent difference with a series of product preferably using same brand in theory
Whitening composition conflicts mutually the adverse reaction of generation.At present, there is skin whitening, moisturizing effect not to the utmost in the whitening moisturizing face masque of in the market
Such as people's will, it is impossible to the problems such as fundamentally improving skin, therefore, it is necessary to develop a kind of natural safety, moisturizing, moisturizing, U.S.
The good whitening moisturizing face masque of white effect.
The content of the invention
In view of the shortcomings of the prior art, it is an object of the invention to provide the fair-skinned bright fine flour film of one kind, its natural safety is accumulate
Composition containing various active, good penetrability can go deep into flesh bottom and largely keep the skin wet and nutrient, replenishing water and preserving moisture, nourish maintenance, whitening flesh
Skin, dispelling stain improves the dark yellow state of skin, recovers pale penetrating.The fair-skinned bright fine flour film that the present invention is provided has good
Moisturizing, moisturizing, whitening effect.
To achieve these goals, technical scheme is as follows：
A kind of fair-skinned bright fine flour film, includes the component of following percentage by weight meter：
Propane diols 4-6%, ethoxy urea 1-3%, glycine betaine 0.5-1.5%, 3-O- ethylascorbyl 0.5-1.5%,
Ursin 0.5-1.5%, purslane extract 0.4-0.6%, thyme extract 0.4-0.6%, tree peony whitening elite 0.4-
0.6%th, panthenol 0.4-0.6%, niacinamide 0.4-0.6%, Jojoba wax PEG-120 esters 0.4-0.6%, tranexamic acid 0.2-
0.4%th, carbomer 0.05-0.15%, triethanolamine 0.07-0.11%, Sodium Hyaluronate 0.04-0.08%, PEG-40 hydrogenation
Castor oil 0.03-0.06%, methyl hydroxybenzoate 0.04-0.06%, Phenoxyethanol/Sensiva SC50 0.1-0.3%, para hydroxybenzene
Ethyl ketone 0.1-0.5%, essence 0.004-0.006% and water 81.234-90.466%.
Further, the fair-skinned bright fine flour film is made up of the component of following percentage by weight meter：
Propane diols 5%, ethoxy urea 2%, glycine betaine 1%, 3-O- ethylascorbyls 1%, ursin 1%, purslane
Extract 0.5%, thyme extract 0.5%, tree peony whitening elite 0.5%, panthenol 0.5%, niacinamide 0.5%, Jojoba
Wax PEG-120 esters 0.5%, tranexamic acid 0.3%, carbomer 0.1%, triethanolamine 0.09%, Sodium Hyaluronate 0.06%,
Cremophor RH40 0.05%, methyl hydroxybenzoate 0.05%, Phenoxyethanol/Sensiva SC50 0.15%, para hydroxybenzene second
Ketone 0.3%, essence 0.005% and water 85.895%.
In technical solution of the present invention, described 3-O- ethylascorbyls can suppress the activity of tyrosinase, suppress
The formation of melanin, reduction melanin is colourless, efficient skin whitening, also has remarkable antioxidant effect.The ursin energy
Skin is enough rapidly permeated into, effectively suppresses the activity of the tyrosinase in skin, blocks the formation of melanin, pass through itself and junket
Propylhomoserin enzyme is directly in conjunction with accelerating the decomposition and excretion of melanin, so as to reduce Skin pigmentation, dispelling stain and freckle.
The purslane extract has anti-inflammatory, antiallergy and acne-removal function.The thyme extract can prevent black
" step " of element, is handled upside down by the amount for reducing the driving albumen that melanin is carried into epidermal cell to suppress melanin, from
And reach whitening effect.The tree peony whitening elite can suppress the effect of tyrosinase, so as to suppress melanin transfer to cutin
Cell, suppresses melanin and produces, and even skin tone highlights the glossiness of skin, reduces visual spot.
The fair-skinned bright fine flour film of the present invention contains the various actives such as 3-O- ethylascorbyls, ursin, thyme extract
Composition, in conjunction with propane diols of the present invention, ethoxy urea, glycine betaine, panthenol, niacinamide, Jojoba wax PEG-120 esters, blood coagulation
The basic materials such as acid, each component synergy so that the fair-skinned bright fine flour film of the present invention can permeate flesh bottom layer by layer, supplement large quantity of moisture
Nutrient, water lock moisturizing, makes whitening composition more preferably play effect, gos deep into flesh bottom and suppresses tyrosinase activity, reduces flesh bottom melanin
Generation, hinders the epidermotropic migration of melanin, disintegrates obstinate melanin, and discharge flesh bottom melanin allows skin to reply white as baby
It is tender, glow.
Present invention also offers the preparation method of above-mentioned fair-skinned bright fine flour film, comprise the following steps：
S1 mixes Cremophor RH40 and essence, stirs up to transparent, obtains solution A；
S2 takes the water of half amount, adds carbomer into above-mentioned water, stirs, and places 8-10h, obtains carbomer and be swelled
Liquid；
S3 added into carbomer swelling solution obtained by step S2 remaining water, propane diols, Sodium Hyaluronate, ethoxy urea,
Glycine betaine, Jojoba wax PEG-120 esters, methyl hydroxybenzoate, are stirred and heated to 80-90 DEG C, are incubated 20-40min, obtain material B；
Step S3 resulting materials B is cooled to 38-42 DEG C by S4, is added triethanolamine, purslane extract, thyme and is extracted
Thing, tree peony whitening elite, 3-O- ethylascorbyls, ursin, panthenol, niacinamide, tranexamic acid, Phenoxyethanol/ethylhexyl
Glycerine, parahydroxyacet-ophenone and step S1 resulting solution A, are stirred until homogeneous, and are down to normal temperature, and sampling inspection is qualified to discharge afterwards, i.e.,
.
Further, the step S2 places 9h.
Further, the step S3 is stirred and heated to 85 DEG C.
Further, the step S3 insulations 30min.
Further, step S3 resulting materials B is cooled to 40 DEG C by the step S4.
Further, the mixing speed of the stirring is 55-65r/min.
Further, the mixing speed of the stirring is 60r/min.
Compared with prior art, the fair-skinned bright fine flour film that the present invention is provided has the advantage that：
(1) the fair-skinned bright fine flour film that provides of the present invention contain 3-O- ethylascorbyls, ursin, purslane extract,
A variety of active skull cap components such as thyme extract, tree peony whitening elite, abundant nourishing, deep water supplement, water lock are provided for skin
Moisten, it is coarse and tight to be effectively improved drying, whiteness of skin can be made to become exquisiteness, smooth pliable highlights skin overall brightness, change
Kind elasticity of skin, so as to reach natural whitening from inside to outside.
(2) the fair-skinned bright fine flour film that the present invention is provided nurses one's health skin from inside to outside, and dispelling stain improves the dark yellow shape of skin
State, prevention pigment generation.
(3) the fair-skinned bright fine flour membrane safety that the present invention is provided is stable, and good penetrability easily absorbs, salubrious not using rear skin
It is sticky.
(4) preparation method for the fair-skinned bright fine flour film that the present invention is provided is simple, and condition is controllable, process stabilizing, and can promote should
With.
Embodiment
Below by way of the description of embodiment, the invention will be further described, but this is not the limit to the present invention
System, those skilled in the art are according to the basic thought of the present invention, and various modifications may be made or improves, but without departing from this
The basic thought of invention, within the scope of the present invention.
Purslane extract of the present invention is purchased from Xi'an Wei Zhen bio tech ltd, article No.：virgin20161215；
Thyme extract is purchased from Shaanxi Hui Ke plants development corporation, Ltd., article No.：4392；Tree peony whitening elite is purchased from Guang Zhoukang
Microbial Technics Ltd, article No.：H16031502.Cremophor RH40 is purchased from the green Sheng limited public affairs of trade in Guangzhou
Department, the model/trade mark：Sympatens-TRH/400.
Embodiment 1, a kind of fair-skinned bright fine flour film
The fair-skinned bright fine flour film is made up of the component of following percentage by weight meter：
Propane diols 4%, ethoxy urea 1%, glycine betaine 0.5%, 3-O- ethylascorbyls 0.5%, ursin 0.5%,
Purslane extract 0.4%, thyme extract 0.4%, tree peony whitening elite 0.4%, panthenol 0.4%, niacinamide 0.4%,
Jojoba wax PEG-120 esters 0.4%, tranexamic acid 0.2%, carbomer 0.05%, triethanolamine 0.07%, Sodium Hyaluronate
0.04%th, Cremophor RH40 0.03%, methyl hydroxybenzoate 0.04%, Phenoxyethanol 0.1%, parahydroxyacet-ophenone 0.1%,
Essence 0.004% and water 90.466%.
Preparation method：
S1 mixes Cremophor RH40 and essence, stirs up to transparent, obtains solution A；
S2 takes the water of half amount, adds carbomer into above-mentioned water, stirs, and places 8h, obtains carbomer swelling solution；
S3 added into carbomer swelling solution obtained by step S2 remaining water, propane diols, Sodium Hyaluronate, ethoxy urea,
Glycine betaine, Jojoba wax PEG-120 esters, methyl hydroxybenzoate, are stirred and heated to 80 DEG C, are incubated 20min, obtain material B；
Step S3 resulting materials B is cooled to 38 DEG C by S4, add triethanolamine, purslane extract, thyme extract,
Tree peony whitening elite, 3-O- ethylascorbyls, ursin, panthenol, niacinamide, tranexamic acid, Phenoxyethanol/ethylhexyl are sweet
Oil, parahydroxyacet-ophenone and step S1 resulting solution A, are stirred until homogeneous, and are down to normal temperature, and sampling inspection is qualified to discharge afterwards, i.e.,
.
The mixing speed of above-mentioned stirring is 55r/min.
Embodiment 2, a kind of fair-skinned bright fine flour film
The fair-skinned bright fine flour film is made up of the component of following percentage by weight meter：
Propane diols 6%, ethoxy urea 3%, glycine betaine 1.5%, 3-O- ethylascorbyls 1.5%, ursin 1.5%,
Purslane extract 0.6%, thyme extract 0.6%, tree peony whitening elite 0.6%, panthenol 0.6%, niacinamide 0.6%,
Jojoba wax PEG-120 esters 0.6%, tranexamic acid 0.4%, carbomer 0.15%, triethanolamine 0.11%, Sodium Hyaluronate
0.08%th, Cremophor RH40 0.06%, methyl hydroxybenzoate 0.06%, Sensiva SC50 0.3%, parahydroxyacet-ophenone
0.5%th, essence 0.006% and water 81.234%.
Preparation method：
S1 mixes Cremophor RH40 and essence, stirs up to transparent, obtains solution A；
S2 takes the water of half amount, adds carbomer into above-mentioned water, stirs, and places 10h, obtains carbomer swelling solution；
S3 added into carbomer swelling solution obtained by step S2 remaining water, propane diols, Sodium Hyaluronate, ethoxy urea,
Glycine betaine, Jojoba wax PEG-120 esters, methyl hydroxybenzoate, are stirred and heated to 90 DEG C, are incubated 40min, obtain material B；
Step S3 resulting materials B is cooled to 42 DEG C by S4, add triethanolamine, purslane extract, thyme extract,
Tree peony whitening elite, 3-O- ethylascorbyls, ursin, panthenol, niacinamide, tranexamic acid, Phenoxyethanol/ethylhexyl are sweet
Oil, parahydroxyacet-ophenone and step S1 resulting solution A, are stirred until homogeneous, and are down to normal temperature, and sampling inspection is qualified to discharge afterwards, i.e.,
.
The mixing speed of above-mentioned stirring is 65r/min.
Embodiment 3, a kind of fair-skinned bright fine flour film
The fair-skinned bright fine flour film is made up of the component of following percentage by weight meter：
Propane diols 5%, ethoxy urea 2%, glycine betaine 1%, 3-O- ethylascorbyls 1%, ursin 1%, purslane
Extract 0.5%, thyme extract 0.5%, tree peony whitening elite 0.5%, panthenol 0.5%, niacinamide 0.5%, Jojoba
Wax PEG-120 esters 0.5%, tranexamic acid 0.3%, carbomer 0.1%, triethanolamine 0.09%, Sodium Hyaluronate 0.06%,
Cremophor RH40 0.05%, methyl hydroxybenzoate 0.05%, Sensiva SC50 0.15%, parahydroxyacet-ophenone 0.3%, perfume
Essence 0.005% and water 85.895%.
Preparation method：
S1 mixes Cremophor RH40 and essence, stirs up to transparent, obtains solution A；
S2 takes the water of half amount, adds carbomer into above-mentioned water, stirs, and places 9h, obtains carbomer swelling solution；
S3 added into carbomer swelling solution obtained by step S2 remaining water, propane diols, Sodium Hyaluronate, ethoxy urea,
Glycine betaine, Jojoba wax PEG-120 esters, methyl hydroxybenzoate, are stirred and heated to 85 DEG C, are incubated 30min, obtain material B；
Step S3 resulting materials B is cooled to 40 DEG C by S4, add triethanolamine, purslane extract, thyme extract,
Tree peony whitening elite, 3-O- ethylascorbyls, ursin, panthenol, niacinamide, tranexamic acid, Phenoxyethanol/ethylhexyl are sweet
Oil, parahydroxyacet-ophenone and step S1 resulting solution A, are stirred until homogeneous, and are down to normal temperature, and sampling inspection is qualified to discharge afterwards, i.e.,
.
The mixing speed of above-mentioned stirring is 60r/min.
Comparative example 1, a kind of fair-skinned bright fine flour film
The fair-skinned bright fine flour film is made up of the component of following percentage by weight meter：
Propane diols 5%, ethoxy urea 2%, glycine betaine 1%, 3-O- ethylascorbyls 1%, ursin 1%, purslane
Extract 0.5%, herba hedyotis diffusae extract 0.5%, tree peony whitening elite 0.5%, panthenol 0.5%, niacinamide 0.5%, suddenly
Bar wax PEG-120 esters 0.5%, tranexamic acid 0.3%, carbomer 0.1%, triethanolamine 0.09%, Sodium Hyaluronate suddenly
0.06%th, Cremophor RH40 0.05%, methyl hydroxybenzoate 0.05%, Sensiva SC50 0.15%, parahydroxyacet-ophenone
0.3%th, essence 0.005% and water 85.895%.
Preparation method is similar to Example 3, as different from Example 3, and thyme extract is replaced with into oldenlandia
Careless extract.
Comparative example 2, a kind of fair-skinned bright fine flour film
The fair-skinned bright fine flour film is made up of the component of following percentage by weight meter：
Propane diols 5%, ethoxy urea 2%, glycine betaine 1%, 3-O- ethylascorbyls 1%, ursin 1%, purslane
Extract 0.5%, thyme extract 0.5%, rose whitening elite 0.5%, panthenol 0.5%, niacinamide 0.5%, Jojoba
Wax PEG-120 esters 0.5%, tranexamic acid 0.3%, carbomer 0.1%, triethanolamine 0.09%, Sodium Hyaluronate 0.06%,
Cremophor RH40 0.05%, methyl hydroxybenzoate 0.05%, Sensiva SC50 0.15%, parahydroxyacet-ophenone 0.3%, perfume
Essence 0.005% and water 85.895%.
Preparation method is similar to Example 3, as different from Example 3, and tree peony whitening elite is replaced with into rose whitening
Elite.
The safety evaluatio of test example one, fair-skinned bright fine flour film
1st, tested material：Fair-skinned bright fine flour film made from embodiment 1, embodiment 2, embodiment 3, comparative example 1 and comparative example 2.
2nd, study subject：
100 women trial volunteers, age 22-55 Sui, subjects skin health, no skin disease allergies, meet by
Examination person volunteers inclusion criteria.
3rd, test method：
100 women trial volunteers are randomly divided into 5 groups, respectively 1 group of embodiment, 2 groups of embodiment, 3 groups of embodiment,
2 groups of 1 group of comparative example and comparative example, every group of 20 people, respectively using embodiment 1, embodiment 2, embodiment 3, comparative example 1 and comparative example
Fair-skinned bright fine flour film made from 2.
Device is tried from qualified spot, with closed patch experiment method, 0.020g tested materials are added in spot examination device, external application
Special adhesive tape, which is covered on after subject back, 24h, removes tested material, 0.5h, 6h, 12h, 24h, 48h observation skin after removing respectively
Skin reacts, according to《Cosmetics health specification》Middle dermoreaction grade scale records its result.
4th, result of the test：
Human skin patch result is shown：Each group subject is fair-skinned by embodiment 1-3, comparative example 1 and comparative example 2
The patch test of bright fine flour film, dermoreaction is observed in 0.5h, 6h, 12h, 24h, 48h, and all subjects do not occur skin
Adverse reaction, this explanation fair-skinned bright fine flour film produced by the present invention uses safety.
The whitening effect evaluation of test example two, fair-skinned bright fine flour film
1st, given the test agent：Fair-skinned bright fine flour made from embodiment 1, embodiment 2, embodiment 3, comparative example 1 and comparative example 2
Film.
2nd, test method：
Choose 50 female subjects and participate in experiment, age 20-46 Sui, subject's exclusion condition meets《Cosmetics are contacted
Property dermatitis diagnostic criteria and treatment principle》Include, exclusion standard.Test position is inner side of cranking arm, and the left and right arm of random arrangement is
Tested area, before experiment, each subject's recipient site dermal melanin content is tested using dermal melanin and ferroheme tester
All subjects are randomly divided into 5 groups, every group of 10 people, respectively 1 group of embodiment, 2 groups of embodiment, implementation by MI values according to MI values
2 groups of 3 groups of example, 1 group of comparative example and comparative example, are made using embodiment 1, embodiment 2, embodiment 3, comparative example 1 and comparative example 2 respectively
The fair-skinned bright fine flour film obtained, night applies once, and continuous to use 12 weeks, recipient site is without using other cosmetics during experiment.Profit
With dermal melanin and ferroheme tester, dermal melanin content MI values after each subject's recipient site experiment are tested.Test
Need to clean recipient site before dermal melanin content MI values.
3rd, result of the test：
Result of the test is as shown in table 1.
Table 1：Influence of the fair-skinned bright fine flour film to dermal melanin content MI values
As can be seen from Table 1, compared with the subject of 2 groups of 1 group of comparative example and comparative example, embodiment 1-3 group subjects'
Dermal melanin content MI values are significantly reduced, and fair-skinned bright fine flour film obtained by this explanation embodiment of the present invention 1-3 can be significantly reduced
Dermal melanin content MI values, the fair-skinned bright fine flour film that the present invention is provided has significant whitening effect.
The anti-aging effects evaluation of test example three, fair-skinned bright fine flour film
1st, given the test agent：Fair-skinned bright fine flour made from embodiment 1, embodiment 2, embodiment 3, comparative example 1 and comparative example 2
Film.
2nd, experimental animal：80 take healthy kunming mice, 9-11 week old, body weight 40g, male and female half and half.
3rd, test method：
Kunming mice is randomly divided into 2 groups of 1 group of embodiment, 2 groups of embodiment, 3 groups of embodiment, 1 group of comparative example and comparative example,
Every group 16, male and female half and half are smeared embodiment 1, embodiment 2, embodiment 3, comparative example 1 and comparative example 2 and are made respectively during experiment
Fair-skinned bright fine flour film.
Each group mouse is lost hair or feathers with 0.8% vulcanized sodium back, exposure 4cm × 4cm test section.Smear before given the test agent
Skin is first cleaned with warm water, daily night smears once corresponding fair-skinned bright fine flour film, continuous to smear one month, during which shaves in time
Remove the mouse hair newly grown.Last is smeared after 12h, clip mouse test section skin histology, prepares skin histology homogenate, determines super
Superoxide dismutase (SOD) vigor and MDA (MDA) content.
4th, result of the test：
Result of the test is as shown in table 2.
Table 2：SOD vigor, the influence of MDA contents during fair-skinned bright fine flour film is homogenized to skin histology
| Group | SOD(U/mgprot) | MDA(nmol/mgprot) |
| Blank control group | 122.67 | 3.83 |
| 1 group of embodiment | 178.48 | 2.53 |
| 2 groups of embodiment | 180.36 | 2.42 |
| 3 groups of embodiment | 184.53 | 2.36 |
| 1 group of comparative example | 142.96 | 3.42 |
| 2 groups of comparative example | 148.17 | 3.25 |
As can be seen from Table 2, the present invention applies the work that fair-skinned bright fine flour film made from a 1-3 is remarkably improved SOD in skin
Power, reduces MDA content, and this explanation, the fair-skinned bright fine flour film that the present invention is provided has good anti-aging effects.
The moisture retention effect assessment of test example four, fair-skinned bright fine flour film
1st, given the test agent：Fair-skinned bright fine flour made from embodiment 1, embodiment 2, embodiment 3, comparative example 1 and comparative example 2
Film.
2nd, test method：
Choose 70 female subjects and participate in experiment, age 21-48 Sui, subject's exclusion condition meets《Cosmetics are contacted
Property dermatitis diagnostic criteria and treatment principle》Include, exclusion standard.70 subjects are randomly divided into 5 groups, every group of 14 people.
Test environment temperature is 25 DEG C of constant temperature, and relative humidity is 60%, and subject or so forearm is used into alkalescence before test
Dry, expose after perfumed soap cleaning, in such circumstances rest half an hour.4cm × 4cm is respectively being marked on subject or so forearm just
Square tested region, left arm is applies the tested region of fair-skinned bright fine flour film, and the symmetrical region of right arm is the tested area of blank control.Make
With Corneometer CM 825PC tester probes, 10 points of selection are measured (single-measurement) in tested region, and
Record mean values are used as benchmark.Using Corneometer CM 825PC tester probes, continuously measured in tested region
70 seconds (continuous measurement), and mean values are recorded as benchmark.The fair-skinned bright fine flour films of 1g are taken to be applied to tested area, it is uniform on skin
Smear 2min.In 0.5h, 1h, 2h, 4h, 6h, single and continuous measurement is carried out respectively in recipient site using probe, and record survey
Test result.Calculate moisture of skin percentage change in different time points.
3rd, result of the test：
Result of the test is as shown in Table 3 and Table 4.
Table 3：The fair-skinned bright single test result of fine flour film moisture retention
Table 4：Fair-skinned bright fine flour film moisture retention follow-on test result
It can be seen from table 3 and table 4 compared with the moisture retention of fair-skinned bright fine flour film made from comparative example 1 and comparative example 2,
The moisture retention of fair-skinned bright fine flour film prepared by the present invention is dramatically increased.This explanation, the fair-skinned bright fine flour film of the present invention can be carried significantly
The moisture retention of high skin, and with good lasting moistening effect.
The resultant effect evaluation of test example five, fair-skinned bright fine flour film
1st, test material：Fair-skinned bright fine flour prepared by embodiment 1, embodiment 2, embodiment 3, comparative example 1 and comparative example 2
Film.
2nd, tested crowd：100 female subjects are chosen, the age, subjects skin's health met between 25~40 years old
Subject volunteers inclusion criteria.
3rd, test method：
Subject is randomly divided into 5 groups, every group of 20 people, respectively 1 group of embodiment, 2 groups of embodiment, 3 groups of embodiment, contrast
2 groups of 1 group of example and comparative example, the fair-skinned bright fine flour film prepared respectively using 1-3 of the embodiment of the present invention, and comparative example 1 and contrast
Fair-skinned bright fine flour film prepared by example 2.After each group subject cleaning face, product of the present invention is coated on the face.
4th, result of the test
Result of the test is as shown in table 5.
Table 5：Each evaluation result of synthesis of fair-skinned bright fine flour film compares
As can be seen from Table 5, compared with fair-skinned bright fine flour film prepared by comparative example 1 and comparative example 2,1- of the embodiment of the present invention
The 3 moist degree of fair-skinned bright fine flour films prepared, ductility, mildness, absorbability, yellow effect of dispelling and freckle effect substantially compared with
Good, this illustrates, each component is mutually cooperateed with the fair-skinned bright fine flour film of the present invention, and resultant effect is optimal.
Tester reacts, and the fair-skinned bright fine flour membrane permeability of the present invention is good, easily absorbs, salubrious not sticky using rear skin, mends
Water moisturizing, it is coarse and tight to can effectively improve drying, and whiteness of skin can be made to become fine and smooth, smooth pliable, skin is highlighted overall bright
Degree, improves elasticity of skin, nourishes maintenance.Being used for a long time being capable of skin whitening, dispelling stain, the improvement dark yellow state of skin, recovery
It is pale penetrating.All testers do not occur allergic phenomena.
Claims (9)
1. a kind of fair-skinned bright fine flour film, it is characterised in that include the component of following percentage by weight meter：
Propane diols 4-6%, ethoxy urea 1-3%, glycine betaine 0.5-1.5%, 3-O- ethylascorbyl 0.5-1.5%, black bearberry
Glycosides 0.5-1.5%, purslane extract 0.4-0.6%, thyme extract 0.4-0.6%, tree peony whitening elite 0.4-
0.6%th, panthenol 0.4-0.6%, niacinamide 0.4-0.6%, Jojoba wax PEG-120 esters 0.4-0.6%, tranexamic acid 0.2-
0.4%th, carbomer 0.05-0.15%, triethanolamine 0.07-0.11%, Sodium Hyaluronate 0.04-0.08%, PEG-40 hydrogenation
Castor oil 0.03-0.06%, methyl hydroxybenzoate 0.04-0.06%, Phenoxyethanol/Sensiva SC50 0.1-0.3%, para hydroxybenzene
Ethyl ketone 0.1-0.5%, essence 0.004-0.006% and water 81.234-90.466%.
2. fair-skinned bright fine flour film as claimed in claim 1, it is characterised in that be made up of the component of following percentage by weight meter：
Propane diols 5%, ethoxy urea 2%, glycine betaine 1%, 3-O- ethylascorbyls 1%, ursin 1%, purslane are extracted
Thing 0.5%, thyme extract 0.5%, tree peony whitening elite 0.5%, panthenol 0.5%, niacinamide 0.5%, Jojoba wax
PEG-120 esters 0.5%, tranexamic acid 0.3%, carbomer 0.1%, triethanolamine 0.09%, Sodium Hyaluronate 0.06%, PEG-
40 rilanit specials 0.05%, methyl hydroxybenzoate 0.05%, Phenoxyethanol/Sensiva SC50 0.15%, parahydroxyacet-ophenone
0.3%th, essence 0.005% and water 85.895%.
3. the preparation method of fair-skinned bright fine flour film as claimed in claim 1 or 2, it is characterised in that comprise the following steps：
S1 mixes Cremophor RH40 and essence, stirs up to transparent, obtains solution A；
S2 takes the water of half amount, adds carbomer into above-mentioned water, stirs, and places 8-10h, obtains carbomer swelling solution；
S3 adds remaining water, propane diols, Sodium Hyaluronate, ethoxy urea, beet into carbomer swelling solution obtained by step S2
Alkali, Jojoba wax PEG-120 esters, methyl hydroxybenzoate, are stirred and heated to 80-90 DEG C, are incubated 20-40min, obtain material B；
Step S3 resulting materials B is cooled to 38-42 DEG C by S4, add triethanolamine, purslane extract, thyme extract,
Tree peony whitening elite, 3-O- ethylascorbyls, ursin, panthenol, niacinamide, tranexamic acid, Phenoxyethanol/ethylhexyl are sweet
Oil, parahydroxyacet-ophenone and step S1 resulting solution A, are stirred until homogeneous, and are down to normal temperature, and sampling inspection is qualified to discharge afterwards, i.e.,
.
4. the preparation method of fair-skinned bright fine flour film as claimed in claim 3, it is characterised in that the step S2 places 9h.
5. the preparation method of fair-skinned bright fine flour film as claimed in claim 3, it is characterised in that the step S3 is stirred and heated
To 85 DEG C.
6. the preparation method of fair-skinned bright fine flour film as claimed in claim 3, it is characterised in that the step S3 is incubated 30min.
7. the preparation method of fair-skinned bright fine flour film as claimed in claim 3, it is characterised in that the step S4 is by step S3 institutes
Obtain material B and be cooled to 40 DEG C.
8. the preparation method of fair-skinned bright fine flour film as claimed in claim 3, it is characterised in that the mixing speed of the stirring is
55-65r/min。
9. the preparation method of fair-skinned bright fine flour film as claimed in claim 8, it is characterised in that the mixing speed of the stirring is
60r/min。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710424386.2A CN107213063B (en) | 2017-06-07 | 2017-06-07 | Fair and bright facial mask and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710424386.2A CN107213063B (en) | 2017-06-07 | 2017-06-07 | Fair and bright facial mask and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107213063A true CN107213063A (en) | 2017-09-29 |
| CN107213063B CN107213063B (en) | 2020-09-18 |
Family
ID=59948233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710424386.2A Active CN107213063B (en) | 2017-06-07 | 2017-06-07 | Fair and bright facial mask and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107213063B (en) |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107854328A (en) * | 2017-10-16 | 2018-03-30 | 上海怡硕净化科技有限公司 | A kind of PA4 efficiently highlights skin care item |
| CN108158875A (en) * | 2017-12-22 | 2018-06-15 | 安婕妤化妆品科技股份有限公司 | A kind of lightening compositions and preparation method thereof |
| CN108309817A (en) * | 2018-04-17 | 2018-07-24 | 西安天丰生物科技有限公司 | A kind of whitening mask Essence and preparation method thereof using resveratrol |
| CN108478453A (en) * | 2018-02-26 | 2018-09-04 | 广州丽彦妆生物科技有限公司 | Hyaluronic acid face mask liquid and preparation method thereof |
| CN108653037A (en) * | 2018-07-27 | 2018-10-16 | 北京斯利安药业有限公司 | Skin conditioning agent composition, its application and whitening mask |
| CN108938507A (en) * | 2018-10-12 | 2018-12-07 | 广州市薏莉雅生物技术开发有限公司 | A kind of whitening essence liquid and preparation method thereof |
| CN109662902A (en) * | 2019-02-20 | 2019-04-23 | 广州娇美生物科技有限公司 | A kind of beautiful skin facial mask liquid and preparation method containing arbutin active matter |
| CN110613654A (en) * | 2019-11-04 | 2019-12-27 | 菲朗生物科技(湖北)有限公司 | Polypeptide compact mask liquid and preparation method thereof |
| CN110755348A (en) * | 2019-11-27 | 2020-02-07 | 邹杰 | Skin care composition and preparation method thereof |
| CN110893169A (en) * | 2019-12-23 | 2020-03-20 | 广州微肽生物科技有限公司 | Whitening and moisturizing mask and preparation method thereof |
| CN110917054A (en) * | 2019-12-11 | 2020-03-27 | 广州皇伽生物科技有限公司 | Whitening and freckle-removing composition for skin care product |
| CN112569165A (en) * | 2020-12-09 | 2021-03-30 | 广州富妆生物科技有限公司 | Moisturizing, whitening and repairing mask composition, mask and preparation method of mask |
| CN112641695A (en) * | 2021-01-13 | 2021-04-13 | 贵州大隆药业有限责任公司 | Moisturizing and anti-aging mask and preparation method thereof |
| CN113952271A (en) * | 2019-12-16 | 2022-01-21 | 株洲千金药业股份有限公司 | Skin moistening and repairing compound and mask essence |
| CN115990130A (en) * | 2023-03-25 | 2023-04-21 | 广州华厦生物制药有限公司 | Face-cleaning porcelain Bai Xuefu mask |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101179654B1 (en) * | 2009-07-20 | 2012-09-04 | 주식회사 인섹트 바이오텍 | Skin care mask using hydrogel containing arazyme |
| CN104666224A (en) * | 2015-02-06 | 2015-06-03 | 广州九美仟惠生物科技有限公司 | Facial mask having efficient skin activating function and preparation method of facial mask |
| CN104887609A (en) * | 2015-06-19 | 2015-09-09 | 广州科玛生物科技有限公司 | Moisturizing mask liquid and preparation method thereof |
| CN106176566A (en) * | 2016-08-23 | 2016-12-07 | 上海新高姿化妆品有限公司 | Cosmetic composition with white-skinned face function and preparation method thereof |
| CN106265236A (en) * | 2016-08-15 | 2017-01-04 | 广州澳希亚实业有限公司 | A kind of lightening compositions and the skin care item containing said composition |
| CN106361635A (en) * | 2016-09-19 | 2017-02-01 | 厦门市香妃美业化妆品有限公司 | Phytoextration multipurpose color changeable cream and preparing method thereof |
-
2017
- 2017-06-07 CN CN201710424386.2A patent/CN107213063B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101179654B1 (en) * | 2009-07-20 | 2012-09-04 | 주식회사 인섹트 바이오텍 | Skin care mask using hydrogel containing arazyme |
| CN104666224A (en) * | 2015-02-06 | 2015-06-03 | 广州九美仟惠生物科技有限公司 | Facial mask having efficient skin activating function and preparation method of facial mask |
| CN104887609A (en) * | 2015-06-19 | 2015-09-09 | 广州科玛生物科技有限公司 | Moisturizing mask liquid and preparation method thereof |
| CN106265236A (en) * | 2016-08-15 | 2017-01-04 | 广州澳希亚实业有限公司 | A kind of lightening compositions and the skin care item containing said composition |
| CN106176566A (en) * | 2016-08-23 | 2016-12-07 | 上海新高姿化妆品有限公司 | Cosmetic composition with white-skinned face function and preparation method thereof |
| CN106361635A (en) * | 2016-09-19 | 2017-02-01 | 厦门市香妃美业化妆品有限公司 | Phytoextration multipurpose color changeable cream and preparing method thereof |
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107854328A (en) * | 2017-10-16 | 2018-03-30 | 上海怡硕净化科技有限公司 | A kind of PA4 efficiently highlights skin care item |
| CN108158875A (en) * | 2017-12-22 | 2018-06-15 | 安婕妤化妆品科技股份有限公司 | A kind of lightening compositions and preparation method thereof |
| CN108478453A (en) * | 2018-02-26 | 2018-09-04 | 广州丽彦妆生物科技有限公司 | Hyaluronic acid face mask liquid and preparation method thereof |
| CN108309817A (en) * | 2018-04-17 | 2018-07-24 | 西安天丰生物科技有限公司 | A kind of whitening mask Essence and preparation method thereof using resveratrol |
| CN108653037A (en) * | 2018-07-27 | 2018-10-16 | 北京斯利安药业有限公司 | Skin conditioning agent composition, its application and whitening mask |
| CN108938507A (en) * | 2018-10-12 | 2018-12-07 | 广州市薏莉雅生物技术开发有限公司 | A kind of whitening essence liquid and preparation method thereof |
| CN109662902A (en) * | 2019-02-20 | 2019-04-23 | 广州娇美生物科技有限公司 | A kind of beautiful skin facial mask liquid and preparation method containing arbutin active matter |
| CN110613654A (en) * | 2019-11-04 | 2019-12-27 | 菲朗生物科技(湖北)有限公司 | Polypeptide compact mask liquid and preparation method thereof |
| CN110755348A (en) * | 2019-11-27 | 2020-02-07 | 邹杰 | Skin care composition and preparation method thereof |
| CN110917054A (en) * | 2019-12-11 | 2020-03-27 | 广州皇伽生物科技有限公司 | Whitening and freckle-removing composition for skin care product |
| CN113952271A (en) * | 2019-12-16 | 2022-01-21 | 株洲千金药业股份有限公司 | Skin moistening and repairing compound and mask essence |
| CN110893169A (en) * | 2019-12-23 | 2020-03-20 | 广州微肽生物科技有限公司 | Whitening and moisturizing mask and preparation method thereof |
| CN112569165A (en) * | 2020-12-09 | 2021-03-30 | 广州富妆生物科技有限公司 | Moisturizing, whitening and repairing mask composition, mask and preparation method of mask |
| CN112641695A (en) * | 2021-01-13 | 2021-04-13 | 贵州大隆药业有限责任公司 | Moisturizing and anti-aging mask and preparation method thereof |
| CN115990130A (en) * | 2023-03-25 | 2023-04-21 | 广州华厦生物制药有限公司 | Face-cleaning porcelain Bai Xuefu mask |
| CN115990130B (en) * | 2023-03-25 | 2023-06-13 | 广州华厦生物制药有限公司 | Face-cleaning porcelain Bai Xuefu mask |
Also Published As
| Publication number | Publication date |
|---|---|
| CN107213063B (en) | 2020-09-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107213063A (en) | A kind of fair-skinned bright fine flour film and preparation method thereof | |
| CN101873847B (en) | Composition for skin external application containing complex of herbal extracts | |
| CN110327261A (en) | A kind of compact skin skin care compositions and preparation method thereof | |
| CN110787091B (en) | Itching-relieving and anti-allergy infant washing and protecting preparation and application thereof | |
| CN107233236B (en) | Fair and bright whitening cream and preparation method thereof | |
| CN110755331B (en) | Antibacterial infant washing and caring preparation and application thereof | |
| CN102302439B (en) | Health-care bath foam and preparation method thereof | |
| CN106256339A (en) | Multi-functional face cleaning towel containing vegetalitas collagen protein and manufacture method thereof | |
| CN107822945A (en) | One kind is matched unartificial yeast composition, preparation method and applied in cosmetics | |
| CN107982135A (en) | A kind of shampoo and preparation method thereof | |
| CN107982086A (en) | One kind makeup removing gel and preparation method thereof | |
| CN107157880A (en) | A kind of HERBA DENDROBII moisturizing sleep mask and preparation method thereof | |
| CN110339111A (en) | A kind of cleaning compositions of the hot spring containing mineral | |
| CN105560155A (en) | Cosmetic composition containing goat milk and application thereof | |
| CN109350591A (en) | A kind of U.S. face dried noodle film and preparation method thereof | |
| CN107510617A (en) | Phycocyanin protective agent and preparation method thereof and phycocyanin composition and moisturizing astringent | |
| CN116549372A (en) | Antioxidant composition enhanced by heat as well as preparation method and application thereof | |
| CN113332207B (en) | Whitening face cleaning cream and preparation method thereof | |
| CN107151275A (en) | Tea polysaccharide extract and its application in skin preparations for extenal use | |
| CN107213062B (en) | Fair, transparent and white facial cleanser and preparation method thereof | |
| KR101453281B1 (en) | Cleansing Cosmetic Compositions | |
| CN109464364A (en) | A kind of spot removal and skin care preparation and preparation method containing graphene oxide | |
| JP2001131049A (en) | Skin preparation for external use | |
| KR20190080429A (en) | cosmetic composition having collagen derived from salmon skin | |
| KR20110052095A (en) | Cosmetic composition for moisturizing of skin containing tremella fuciformis extracts |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |