CN110846185B - 一种黄精酒及其制备方法 - Google Patents
一种黄精酒及其制备方法 Download PDFInfo
- Publication number
- CN110846185B CN110846185B CN201911280696.7A CN201911280696A CN110846185B CN 110846185 B CN110846185 B CN 110846185B CN 201911280696 A CN201911280696 A CN 201911280696A CN 110846185 B CN110846185 B CN 110846185B
- Authority
- CN
- China
- Prior art keywords
- extract
- rhizoma polygonati
- wine
- parts
- extraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 235000014101 wine Nutrition 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 241000037831 Polygonatum sibiricum Species 0.000 title description 8
- 239000000284 extract Substances 0.000 claims abstract description 61
- 238000000605 extraction Methods 0.000 claims abstract description 47
- 239000003814 drug Substances 0.000 claims abstract description 31
- 238000000855 fermentation Methods 0.000 claims abstract description 31
- 230000004151 fermentation Effects 0.000 claims abstract description 31
- 238000001914 filtration Methods 0.000 claims abstract description 31
- 235000017784 Mespilus germanica Nutrition 0.000 claims abstract description 17
- 235000000560 Mimusops elengi Nutrition 0.000 claims abstract description 17
- 235000007837 Vangueria infausta Nutrition 0.000 claims abstract description 17
- 238000002156 mixing Methods 0.000 claims abstract description 11
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 10
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims abstract description 10
- 241000756042 Polygonatum Species 0.000 claims abstract description 9
- 239000000919 ceramic Substances 0.000 claims abstract description 6
- 239000012528 membrane Substances 0.000 claims abstract description 6
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 238000000108 ultra-filtration Methods 0.000 claims abstract description 6
- 241001633680 Polygonatum odoratum Species 0.000 claims abstract description 4
- 240000002624 Mespilus germanica Species 0.000 claims abstract 5
- 239000007788 liquid Substances 0.000 claims description 21
- 238000010992 reflux Methods 0.000 claims description 21
- 239000012153 distilled water Substances 0.000 claims description 20
- 238000010298 pulverizing process Methods 0.000 claims description 20
- 238000007873 sieving Methods 0.000 claims description 20
- 238000002137 ultrasound extraction Methods 0.000 claims description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
- 239000002904 solvent Substances 0.000 claims description 18
- 238000009835 boiling Methods 0.000 claims description 15
- 235000020097 white wine Nutrition 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 11
- 230000001105 regulatory effect Effects 0.000 claims description 10
- 230000032683 aging Effects 0.000 claims description 8
- 229940079593 drug Drugs 0.000 claims description 8
- 150000004676 glycans Chemical class 0.000 claims description 8
- 229920001282 polysaccharide Polymers 0.000 claims description 8
- 239000005017 polysaccharide Substances 0.000 claims description 8
- 230000001954 sterilising effect Effects 0.000 claims description 7
- 238000009928 pasteurization Methods 0.000 claims description 6
- 108010059892 Cellulase Proteins 0.000 claims description 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 5
- 229940106157 cellulase Drugs 0.000 claims description 5
- 239000008103 glucose Substances 0.000 claims description 5
- 238000007789 sealing Methods 0.000 claims description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims 2
- 238000011081 inoculation Methods 0.000 claims 1
- 239000008280 blood Substances 0.000 abstract description 9
- 210000004369 blood Anatomy 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 9
- 241001468611 Polygonatum cyrtonema Species 0.000 abstract description 4
- 239000000463 material Substances 0.000 abstract description 4
- 239000000126 substance Substances 0.000 abstract description 4
- 238000005352 clarification Methods 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000019634 flavors Nutrition 0.000 abstract 1
- 230000007365 immunoregulation Effects 0.000 abstract 1
- 244000182216 Mimusops elengi Species 0.000 description 12
- 239000000843 powder Substances 0.000 description 12
- 238000009210 therapy by ultrasound Methods 0.000 description 11
- 230000007812 deficiency Effects 0.000 description 6
- 230000036541 health Effects 0.000 description 6
- 210000002784 stomach Anatomy 0.000 description 5
- 230000018109 developmental process Effects 0.000 description 4
- 230000000144 pharmacologic effect Effects 0.000 description 4
- 238000011160 research Methods 0.000 description 4
- 210000000952 spleen Anatomy 0.000 description 4
- 206010011224 Cough Diseases 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 206010012601 diabetes mellitus Diseases 0.000 description 3
- 230000036039 immunity Effects 0.000 description 3
- 239000002054 inoculum Substances 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 241000234280 Liliaceae Species 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 208000031971 Yin Deficiency Diseases 0.000 description 2
- 244000126002 Ziziphus vulgaris Species 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 230000001476 alcoholic effect Effects 0.000 description 2
- 208000022531 anorexia Diseases 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 206010061428 decreased appetite Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000003127 knee Anatomy 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 150000005856 steroid saponins Chemical class 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 229940126680 traditional chinese medicines Drugs 0.000 description 2
- 239000000341 volatile oil Substances 0.000 description 2
- 208000000044 Amnesia Diseases 0.000 description 1
- 208000031091 Amnestic disease Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 206010013789 Dry throat Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- 208000000616 Hemoptysis Diseases 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241001106041 Lycium Species 0.000 description 1
- 102100024295 Maltase-glucoamylase Human genes 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 235000008737 Polygonatum biflorum Nutrition 0.000 description 1
- 206010039424 Salivary hypersecretion Diseases 0.000 description 1
- 241000208292 Solanaceae Species 0.000 description 1
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 1
- 235000008529 Ziziphus vulgaris Nutrition 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 102000004139 alpha-Amylases Human genes 0.000 description 1
- 108090000637 alpha-Amylases Proteins 0.000 description 1
- 108010028144 alpha-Glucosidases Proteins 0.000 description 1
- 229940024171 alpha-amylase Drugs 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000006986 amnesia Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000011132 hemopoiesis Effects 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 230000004957 immunoregulator effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- GOMNOOKGLZYEJT-UHFFFAOYSA-N isoflavone Chemical compound C=1OC2=CC=CC=C2C(=O)C=1C1=CC=CC=C1 GOMNOOKGLZYEJT-UHFFFAOYSA-N 0.000 description 1
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 description 1
- 235000008696 isoflavones Nutrition 0.000 description 1
- 229930013686 lignan Natural products 0.000 description 1
- 150000005692 lignans Chemical class 0.000 description 1
- 235000009408 lignans Nutrition 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 230000010016 myocardial function Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- -1 phytosterol Substances 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000000171 quenching effect Effects 0.000 description 1
- 208000026451 salivation Diseases 0.000 description 1
- OABYVIYXWMZFFJ-ZUHYDKSRSA-M sodium glycocholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 OABYVIYXWMZFFJ-ZUHYDKSRSA-M 0.000 description 1
- JAJWGJBVLPIOOH-IZYKLYLVSA-M sodium taurocholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCS([O-])(=O)=O)C)[C@@]2(C)[C@@H](O)C1 JAJWGJBVLPIOOH-IZYKLYLVSA-M 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 231100000240 steatosis hepatitis Toxicity 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 230000003867 tiredness Effects 0.000 description 1
- 208000016255 tiredness Diseases 0.000 description 1
- 150000003648 triterpenes Chemical class 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 235000014692 zinc oxide Nutrition 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/02—Preparation of other alcoholic beverages by fermentation
- C12G3/026—Preparation of other alcoholic beverages by fermentation with health-improving ingredients, e.g. flavonoids, flavones, polyphenols or polysaccharides, added before or during the fermentation stage; with flavouring ingredients added before or during the fermentation stage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/02—Preparation of other alcoholic beverages by fermentation
- C12G3/024—Preparation of other alcoholic beverages by fermentation of fruits other than botanical genus Vitis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/04—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
- C12G3/05—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs with health-improving ingredients, e.g. flavonoids, flavones, polyphenols or polysaccharides
- C12G3/055—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs with health-improving ingredients, e.g. flavonoids, flavones, polyphenols or polysaccharides extracted from plants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Botany (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种黄精酒及其制备方法，是由包括如下质量份的原料加工获得：原酒56‑68份，黄精提取液20‑30份，枸杞提取液10‑15份，红枣提取液10‑15份，玉竹提取液10‑15份。本发明以具有良好的降糖和免疫调节功效的安徽道地药材多花黄精为主要原料，同时辅以红枣、枸杞、玉竹等药食两用物质，采用现代中药提取技术，分别制得黄精、红枣、枸杞、玉竹提取液，并将提取液按一定比例混合，以专用酿酒酵母进行发酵，得发酵液，对发酵液进行初滤，然后采用无机陶瓷膜进行超滤澄清，最后以原酒为基酒，按一定比例加入上述发酵液进行调配，制得酒体清透亮红、酒味醇香独特的健康黄精白酒。
Description
技术领域
本发明涉及一种黄精酒及其制备方法，属于健康白酒领域。
背景技术
近年来，随着社会、经济与科技的快速发展，大健康主题作为民生要点备受政府和社会关注，“健康中国”正式升级成为国家发展战略内容。中国白酒作为与大众生活休戚相关的产业，白酒健康化也会成为白酒行业发展的大趋势，并成为中国传统白酒未来发展的风向标。
所选黄精为九华山多花黄精，属十大皖药之一，为安徽道地药材。《青阳县志》：“黄精虽处处有之，唯九华山者为上。”黄精(学名：Polygonatum sibiricum)是百合科黄精属的植物。《别录》记载：“主补中益气，除风湿，安五脏。”具有补气养阴，健脾，润肺，益肾。用于脾胃气虚，体倦乏力，胃阴不足，口干食少，肺虚燥咳，劳嗽咳血，精血不足，腰膝酸软，须发早白，内热消渴等症状。黄精的化学成分主要包括多糖、甾体皂苷、三萜、生物碱、木脂素、黄酮、植物甾醇及挥发油等，其中黄精多糖为其主要药效成分。现代药理研究发现，黄精具有降低血糖，增强免疫，抗病毒，抗炎，延缓衰老，改善学习记忆等功效。
枸杞是茄目茄科枸杞属(Lycium)的植物。《本草纲目》中记载枸杞“久服坚筋骨，轻身不老，耐寒暑。”中医常用它来治疗肝肾阴亏、腰膝酸软、头晕、健忘、目眩、目昏多泪、消渴等病症。枸杞的主要化学成分为枸杞多糖，现代药理学研究证实枸杞子可调节机体免疫功能、能有效抑制肿瘤生长和细胞突变、具有延缓衰老、抗脂肪肝、调节血脂和血糖、促进造血功能等方面的作用。
红枣是鼠李科枣属植物枣Ziziphus jujuba Mill.var.inermis(Bunge)Rehd.的干燥成熟果实。《本经》：“主心腹邪气，安中养脾，助十二经。平胃气，通九窍，补少气、少津液，身中不足，大惊，四肢重，和百药。”补中益气，养血安神。用于脾虚食少，乏力便溏，妇人脏躁。现代药理研究证实大枣具有增强免疫力，降血糖，抗肿瘤，延缓衰老，改善心肌功能，抗病毒等功效。
玉竹为百合科植物玉竹Polygonatum odoratum(MilL)Druce的干燥根茎。《本经》：“主中风暴热，不能动摇，跌筋结肉，诸不足。久服去面黑野，好颜色，润泽。”养阴润燥，生津止渴。用于肺胃阴伤，燥热咳嗽，咽干口渴，内热消渴。玉竹的主要化学成分为多糖类、甾体皂苷类、高异黄酮类、氨基酸及挥发油类等化合物。现代药理研究证实玉竹具有抗肿瘤作用，抗Ⅰ型变态反应的作用，以及对中枢神经有抑制作用。
目前市场以中药材为原料发酵的保健酒就多为低度酒，口感和色泽较差，不适合大众消费需求；且加工工艺简单，中药活性成分含量低，保健效果不明显等。
发明内容
本发明的目的在于提供一种黄精酒及其制备方法，以获得一款富含降糖和免疫调节活性的植物多糖的健康白酒产品。本发明原材料为黄精、构杞、玉竹、红枣等药食同源中药，药食同源中药既具备食物的丰富营养及食用安全性，又兼顾有药物的治疗效果，具有药用保健价值。
本发明黄精酒是由包括如下质量份的原料加工获得：
原酒56-68份，黄精提取液20-30份，枸杞提取液10-15份，红枣提取液10-15份，玉竹提取液10-15份。
所述原酒为浓香型古井贡酒原酒。
所述黄精提取液是由包括如下步骤的方法制备获得：
将干燥的黄精生药材用中药粉碎机粉碎5-10min，随后过40-60目筛，按1g：10-15mL的比例加入蒸馏水，同时加入1-2％纤维素酶，在50℃下酶解5h，酶解液调节pH至5.0-5.5，然后进行超声提取，提取温度50-55℃，超声功率300W，超声时间30-40min，过滤，得黄精提取液。
所述枸杞提取液是由包括如下步骤的方法制备获得：
将干燥的枸杞药材用中药粉碎机粉碎5-10min，然后过40-60目筛；以蒸馏水为提取溶剂，于50-55℃下超声提取20-30min，料液比1g：15-20mL，超声功率300W；超声提取结束后将体系转移至回流提取装置中，沸腾回流提取30-45min，过滤，得枸杞提取液。
所述红枣提取液是由包括如下步骤的方法制备获得：
将去核的干红枣用中药粉碎机粉碎5-10min，然后过40-60目筛；以蒸馏水为提取溶剂，于50-55℃下超声提取20-30min，料液比1g：15-20mL，超声功率300W；超声提取结束后将体系转移至回流提取装置中，沸腾回流提取30-45min，过滤，得红枣提取液。
所述玉竹提取液是由包括如下步骤的方法制备获得：
将干燥的玉竹药材用中药粉碎机粉碎5-10min，然后过40-60目筛；以蒸馏水为提取溶剂，于50-55℃下超声提取20-30min，料液比1g：6-10mL，超声功率300W；超声提取结束后将体系转移至回流提取装置中，沸腾回流提取30-45min，过滤，得玉竹提取液。
本发明黄精酒的制备方法包括如下步骤：
步骤1：将黄精提取液、枸杞提取液、红枣提取液以及玉竹提取液按照配比量混合，向混合提取液中添加20％-30％的葡萄糖，采用巴氏杀菌法进行灭菌，灭菌时间20-25min，灭菌温度90-95℃；
步骤2：向步骤1获得的灭菌液中接种酿酒酵母B0213发酵，接种量为3-5％，发酵时间5-8天，发酵温度25-30℃；
步骤3：将步骤2获得的发酵液调pH至5.0-5.5，然后送入孔径30nm的无机陶瓷超滤膜进行过滤，过滤压力为0.2-0.3MPa，得到发酵澄清液；
步骤4：将步骤3获得的发酵澄清液和原酒按比例混合调配成酒精度36-38°的黄精白酒，随后置于阴凉避光处密封静置，20-25℃避光陈酿50-60天。
步骤2发酵后获得的发酵液中总多糖含量不低于0.7％。
与现有技术相比，本发明的有益效果体现在：
1、本发明采用超声辅助萃取中药提取液，提取液中总多糖含量达39.36％，有效提高活性物质的含量；
2、本发明提取液、发酵液采用巴氏杀菌法灭菌，避免活性成分在杀菌过程中被破坏；
3、本发明据经典中药配方，并进行了改进，在体外实验中，该黄精白酒对α-葡萄糖苷酶和α-淀粉酶活性的抑制率分别为(84.5±0.574)％和(85.6±2.34)％，与甘氨胆酸钠和牛磺胆酸钠的结合率分别为90.5％和91.7％，在胃环境和肠环境对胆固醇的吸附量分别为0.014mg/g和0.015mg/g。推测该酒具有一定调节血糖、调节血脂等功效。并且保持了白酒的特征和口感。
附图说明
图1是本发明制备方法的流程示意图。
具体实施方式
本实施例在以本发明技术方案为前提下进行实施，给出了详细的实施方式和具体的操作过程，但本发明的保护范围不限于下述的实施例。
实施例1：
1、提取液的制备：
A.黄精提取液制备：将干燥黄精生药材用中药粉碎机打成粉末，粉碎时间为5min，粉碎后的黄精过40目筛。以蒸馏水为提取溶剂按1g：10mL的比例提取，同时加入1％纤维素酶进行酶解，调节至pH5.0进行超声提取，提取温度50℃，超声功率300W，超声时间30min。过滤，得黄精提取液。
B.红枣提取液制备：将去核的干红枣用中药粉碎机打成粉末，粉碎时间为5min，粉碎后的红枣过40目筛。以蒸馏水为提取溶剂，料液比1g：15mL，置于超声波设备中于50℃，超声20min，超声功率300W；然后放置到回流提取装置中，沸腾回流提取30min；提取完成后，过滤，得红枣提取液。
C.玉竹提取液的制备：干燥玉竹药材用中药粉碎机打成粉末，粉碎时间为5min，粉碎后的玉竹过40目筛。以蒸馏水为提取溶剂，料液比1g：6mL，置于超声波设备中于50℃，超声提取20min，超声功率300W；然后置于回流提取装置中，沸腾回流提取30min；提取完成后，过滤，得玉竹提取液。
D.枸杞提取液的制备：干燥枸杞药材用中药粉碎机打成粉末，粉碎时间为5min，粉碎后的枸杞过40目筛。以蒸馏水为提取溶剂，料液比1g：15mL，置于超声波设备中50℃，超声20min，超声功率300W；然后置于回流提取装置中，沸腾回流提取30min；提取完成后，过滤，得枸杞提取液。
2、将黄精提取液20份、枸杞提取液10份、红枣提取液10份、玉竹提取液10份混合均匀，在混合提取液中添加20％葡萄糖，采用巴氏杀菌法进行灭菌，灭菌时间20min，灭菌温度90℃，灭菌液接种酿酒酵母B0213发酵，酵母菌接种量3％、发酵时间5天，发酵温度25℃。
3、将发酵液调pH至5.0，然后将其送入无机陶瓷超滤膜进行过滤，过滤压力为0.2MPa，得到发酵澄清液。
4、将发酵澄清液和56份原酒调成酒精度约37°的黄精白酒，置于阴凉避光处密封静置进行陈酿。
实施例2：
1、提取液的制备：
A.黄精提取液制备：将干燥黄精生药材用中药粉碎机打成粉末，粉碎时间为10min，粉碎后的黄精过60目筛。以蒸馏水为提取溶剂按1g：15mL的比例提取，同时加入2％纤维素酶进行酶解，调节至pH5.5进行超声提取，提取温度55℃，超声功率300W，超声时间40min。过滤，得黄精提取液。
B.红枣提取液制备：将去核的干红枣用中药粉碎机打成粉末，粉碎时间为10min，粉碎后的红枣过60目筛。以蒸馏水为提取溶剂，料液比1g：20mL，置于超声波设备中于55℃，超声30min，超声功率300W；然后放置到回流提取装置中，沸腾回流提取45min；提取完成后，过滤，得红枣提取液。
C.玉竹提取液的制备：干燥玉竹药材用中药粉碎机打成粉末，粉碎时间为10min，粉碎后的玉竹过60目筛。以蒸馏水为提取溶剂，料液比1g：10mL，置于超声波设备中于55℃，超声提取30min，超声功率300W；然后置于回流提取装置中，沸腾回流提取45min；提取完成后，过滤，得玉竹提取液。
D.枸杞提取液的制备：干燥枸杞药材用中药粉碎机打成粉末，粉碎时间为10min，粉碎后的枸杞过60目筛。以蒸馏水为提取溶剂，料液比1g：20mL，置于超声波设备中55℃，超声30min，超声功率300W；然后置于回流提取装置中，沸腾回流提取45min；提取完成后，过滤，得枸杞提取液。
2、将以上所得四种提取液按权利要求1的比例混合，在混合提取液中添加25％葡萄糖，采用巴氏杀菌法进行灭菌，灭菌时间25min，灭菌温度95℃，灭菌液接种酿酒酵母B0213发酵，酵母菌接种量4％、发酵时间7天，发酵温度27℃。
3、将发酵液调pH至5.5，然后将其送入无机陶瓷超滤膜进行过滤，过滤压力为0.3MPa，得到发酵澄清液。
4、将发酵澄清液和原酒按一定的比例调成酒精度约37°的黄精白酒，置于阴凉避光处密封静置进行陈酿。
实施例3：
1、提取液的制备：
A.黄精提取液制备：将干燥黄精生药材用中药粉碎机打成粉末，粉碎时间为7min，粉碎后的黄精过50目筛。以蒸馏水为提取溶剂按1g：12mL的比例提取，同时加入1.5％纤维素酶进行酶解，调节至pH5.2进行超声提取，提取温度52℃，超声功率300W，超声时间35min。过滤，得黄精提取液。
B.红枣提取液制备：将去核的干红枣用中药粉碎机打成粉末，粉碎时间为7min，粉碎后的红枣过50目筛。以蒸馏水为提取溶剂，料液比1g：17mL，置于超声波设备中于52℃，超声25min，超声功率300W；然后放置到回流提取装置中，沸腾回流提取42min；提取完成后，过滤，得红枣提取液。
C.玉竹提取液的制备：干燥玉竹药材用中药粉碎机打成粉末，粉碎时间为7min，粉碎后的玉竹过50目筛。以蒸馏水为提取溶剂，料液比1g：8mL，置于超声波设备中于52℃，超声提取25min，超声功率300W；然后置于回流提取装置中，沸腾回流提取38min；提取完成后，过滤，得玉竹提取液。
D.枸杞提取液的制备：干燥枸杞药材用中药粉碎机打成粉末，粉碎时间为7min，粉碎后的枸杞过50目筛。以蒸馏水为提取溶剂，料液比1g：12mL，置于超声波设备中52℃，超声25min，超声功率300W；然后置于回流提取装置中，沸腾回流提取38min；提取完成后，过滤，得枸杞提取液。
2、将以上所得四种提取液按权利要求1的比例混合，在混合提取液中添加30％葡萄糖，采用巴氏杀菌法进行灭菌，灭菌时间22min，灭菌温度92℃，灭菌液接种酿酒酵母B0213发酵，酵母菌接种量5％、发酵时间8天，发酵温度30℃。
3、将发酵液调pH至5.2，然后将其送入无机陶瓷超滤膜进行过滤，过滤压力为0.25MPa，得到发酵澄清液。
4、将发酵澄清液和原酒按一定的比例调成酒精度约37°的黄精白酒，置于阴凉避光处密封静置进行陈酿。
Claims (3)
1.一种黄精酒的制备方法，其特征在于包括如下步骤：
步骤1：将黄精提取液、枸杞提取液、红枣提取液以及玉竹提取液按照配比量混合，向混合提取液中添加20%-30%的葡萄糖，采用巴氏杀菌法进行灭菌，灭菌时间20-25min，灭菌温度90-95℃；
步骤2：向步骤1获得的灭菌液中接种酿酒酵母B0213发酵，酿酒酵母的接种量为3-5%，发酵时间5-8天，发酵温度25-30℃；
步骤3：将步骤2获得的发酵液调pH至5.0-5.5，然后送入孔径30nm的无机陶瓷超滤膜进行过滤，得到发酵澄清液；
步骤4：将步骤3获得的发酵澄清液和原酒按比例混合调配成酒精度36-38°的黄精白酒，随后置于阴凉避光处密封静置，20-25℃避光陈酿50-60天；
所述黄精酒的原料按质量份数包括：
原酒56-68份，黄精提取液20-30份，枸杞提取液10-15份，红枣提取液10-15份，玉竹提取液10-15份；
所述黄精提取液是由包括如下步骤的方法制备获得：
将干燥的黄精生药材用中药粉碎机粉碎5-10 min，随后过40-60目筛，按1g：10-15mL的比例加入蒸馏水，同时加入1-2%纤维素酶，在50℃下酶解5h，酶解液调节pH至5.0-5.5，然后进行超声提取，提取温度50-55℃，超声功率300 W，超声时间30-40 min，过滤，得黄精提取液；
所述枸杞提取液是由包括如下步骤的方法制备获得：
将干燥的枸杞药材用中药粉碎机粉碎5-10 min，然后过40-60目筛；以蒸馏水为提取溶剂，于50-55℃下超声提取20-30 min，料液比1g：15-20mL，超声功率300W；超声提取结束后将体系转移至回流提取装置中，沸腾回流提取30-45 min，过滤，得枸杞提取液；
所述红枣提取液是由包括如下步骤的方法制备获得：
将去核的干红枣用中药粉碎机粉碎5-10 min，然后过40-60目筛；以蒸馏水为提取溶剂，于50-55℃下超声提取20-30 min，料液比1g：15-20mL，超声功率300W；超声提取结束后将体系转移至回流提取装置中，沸腾回流提取30-45 min，过滤，得红枣提取液；
所述玉竹提取液是由包括如下步骤的方法制备获得：
将干燥的玉竹药材用中药粉碎机粉碎5-10 min，然后过40-60目筛；以蒸馏水为提取溶剂，于50-55℃下超声提取20-30 min，料液比1g：6-10mL，超声功率300W；超声提取结束后将体系转移至回流提取装置中，沸腾回流提取30-45 min，过滤，得玉竹提取液。
2.根据权利要求1所述的制备方法，其特征在于：
步骤2发酵后获得的发酵液中总多糖含量不低于0.7%。
3.根据权利要求1所述的制备方法，其特征在于：
步骤3中，过滤压力为0.2-0.3 MPa。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911280696.7A CN110846185B (zh) | 2019-12-13 | 2019-12-13 | 一种黄精酒及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911280696.7A CN110846185B (zh) | 2019-12-13 | 2019-12-13 | 一种黄精酒及其制备方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110846185A CN110846185A (zh) | 2020-02-28 |
| CN110846185B true CN110846185B (zh) | 2023-10-24 |
Family
ID=69609036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911280696.7A Active CN110846185B (zh) | 2019-12-13 | 2019-12-13 | 一种黄精酒及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110846185B (zh) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110669623A (zh) * | 2019-11-08 | 2020-01-10 | 河南圆梦生物工程有限公司 | 一种菊花养生酒及其制备方法 |
| CN112795458A (zh) * | 2021-03-04 | 2021-05-14 | 杨涛 | 一种养生酒 |
| CN113476553A (zh) * | 2021-07-09 | 2021-10-08 | 马建建 | 一种黄精玉竹细胞再生液 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108753535A (zh) * | 2018-06-27 | 2018-11-06 | 安徽孔氏奇医药科技有限公司 | 一种黄精保健酒的制备工艺 |
-
2019
- 2019-12-13 CN CN201911280696.7A patent/CN110846185B/zh active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108753535A (zh) * | 2018-06-27 | 2018-11-06 | 安徽孔氏奇医药科技有限公司 | 一种黄精保健酒的制备工艺 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110846185A (zh) | 2020-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110846185B (zh) | 一种黄精酒及其制备方法 | |
| CN101496854B (zh) | 一种中药解酒组合物及中药解酒饮料 | |
| CN106244372B (zh) | 一种改善睡眠的酵素化天麻养生饮品及制备工艺及应用 | |
| CN103740566B (zh) | 一种刺梨药酒及其制作方法 | |
| CN102311900B (zh) | 富含营养的养生黄酒 | |
| CN104928113A (zh) | 一种复合发酵型鸭梨保健酒及其生产工艺 | |
| KR20130056639A (ko) | 선옥균과 한약재를 이용한 혈당과 혈압을 개선하는 건강식품 및 그 제조방법 | |
| CN103642624A (zh) | 一种复合发酵型肉苁蓉保健酒及其生产工艺 | |
| CN106635633A (zh) | 一种富硒海蓬子保健酒及生产工艺 | |
| CN110093239B (zh) | 一种诺丽配制酒及其制备方法 | |
| CN104623091A (zh) | 一种灵芝虫草养身酒 | |
| CN107254385A (zh) | 一种水土保持树种果实为原料的酸枣酒及其制备方法 | |
| CN103589570A (zh) | 一种复合发酵型茯苓保健酒及其生产工艺 | |
| CN103602554A (zh) | 一种复合发酵型菟丝子保健酒及其生产工艺 | |
| CN1733885A (zh) | 一种肉苁蓉干红葡萄酒及其制备方法 | |
| CN1041106A (zh) | 一种灵芝精的生产工艺 | |
| CN107012048A (zh) | 含蛹虫草与玛咖的保健酒及其制备方法 | |
| CN103497857B (zh) | 一种具有丰乳健美功能的嘉宝果红酒及其制备方法 | |
| CN100400636C (zh) | 一种三七叶啤酒的酿制方法 | |
| CN112544812A (zh) | 一种产蛋后期蛋鸡用混菌发酵型中草药添加剂及其制备方法和应用 | |
| CN102311901B (zh) | 具有果香的养生保健低度营养黄酒 | |
| CN107684574B (zh) | 具有降血脂功能的药食两用组合物及其制备方法 | |
| CN115245475B (zh) | 六君子发酵物用于制备兼具抗氧化、保湿及控油功效的中草药化妆品组成物的用途 | |
| CN1350860A (zh) | 糖尿病人用的保健口服液生产工艺 | |
| CN106173725A (zh) | 一种灵黄酵素的制作方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |