CN110833520A - Anti-aging composition - Google Patents

Anti-aging composition Download PDF

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Publication number
CN110833520A
CN110833520A CN201911286742.4A CN201911286742A CN110833520A CN 110833520 A CN110833520 A CN 110833520A CN 201911286742 A CN201911286742 A CN 201911286742A CN 110833520 A CN110833520 A CN 110833520A
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aging
aging composition
skin
parts
extract
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CN110833520B (en
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雷强
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Guangzhou Yiermei Biotechnology Co Ltd
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Guangzhou Yiermei Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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    • A61K8/9767Pinaceae [Pine family], e.g. pine or cedar
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/18Antioxidants, e.g. antiradicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10General cosmetic use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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Abstract

The invention relates to the technical field of cosmetic additives, and provides an anti-aging composition aiming at the problem of poor anti-aging effect of an anti-aging product, which comprises the following components in parts by mass: 20-25 parts of maritime pine bark extract; 10-15 parts of bletilla striata root extract; 8-12 parts of polygonum multiflorum extract; and 17-25 parts of a solvent. A preparation method of an anti-aging composition comprises the steps of stirring and uniformly mixing all components of the anti-aging composition according to the mass part ratio to obtain the anti-aging composition. An anti-aging composition is applied by adding into skin care product. The maritime pine bark extract, the bletilla striata root extract and the polygonum multiflorum extract are matched in a synergistic manner, so that the absorption of effective components in the anti-aging composition by a human body is favorably promoted, free radicals are favorably eliminated better, the skin aging speed is favorably delayed better, the anti-aging effect of the anti-aging composition is more remarkable, and the effect is quicker.

Description

Anti-aging composition
Technical Field
The invention relates to the technical field of cosmetic additives, in particular to an anti-aging composition.
Background
Aging is a natural process and is a direct manifestation of the slowing of the body's function.
Various biomolecules in the system have a large number of active groups, and the active groups are bound to interact with each other to generate chemical reaction, so that the biomolecules are slowly crosslinked to tend to be stable in chemical activity. With the lapse of time, the crosslinking degree is increased continuously, the active groups of the biomolecules are consumed and reduced continuously, the original molecular structure is changed gradually, and the aging phenomenon of the biological tissues can be generated gradually due to the accumulation of the changes. Free radicals are the first killers of skin and body accelerated aging.
The extrinsic manifestations of skin aging are: wrinkles are formed, and gradually increased and deepened; loose, dry, and less elastic skin. People hope that the face of people can keep youthful forever just so called 'love heart and everyone's own, so that a lot of anti-aging products appear on the market. However, the existing anti-aging products have poor human body absorption effect, so that the anti-aging effect of the products is poor and slow, and therefore, the improvement space is still left.
Disclosure of Invention
Aiming at the defects in the prior art, the first purpose of the invention is to provide an anti-aging composition with remarkable anti-aging effect and quick response.
The second purpose of the invention is to provide a preparation method of the anti-aging composition, which is simple and convenient to operate.
The third purpose of the invention is to provide the application of the anti-aging composition with wide application range.
In order to achieve the first object, the invention provides the following technical scheme:
an anti-aging composition comprises the following components in parts by mass:
20-25 parts of maritime pine bark extract;
10-15 parts of bletilla striata root extract;
8-12 parts of polygonum multiflorum extract;
and 17-25 parts of a solvent.
By adopting the technical scheme, the maritime pine bark extract, the bletilla striata root extract and the polygonum multiflorum extract are matched with each other in a synergistic manner, so that the absorption of effective components in the anti-aging composition by a human body is favorably promoted, free radicals are favorably eliminated better, the skin aging speed is favorably delayed better, the anti-aging effect of the anti-aging composition is more remarkable, and the effect is quicker.
By adopting the maritime pine bark extract, the bletilla striata root extract and the polygonum multiflorum extract to be matched in a mutual synergistic manner, the skin elasticity is favorably and better improved, the skin wrinkle is favorably reduced while the skin tightness is higher, the wrinkle problem is favorably and better solved from the source, and the anti-aging effect of the anti-aging composition is more continuous.
The invention is further configured to: the solvent is propylene glycol.
By adopting the technical scheme, the propanediol is adopted as the solvent, so that the maritime pine bark extract, the bletilla striata root extract and the polygonum multiflorum extract are favorably dissolved in the solvent better, the maritime pine bark extract, the bletilla striata root extract and the polygonum multiflorum extract are favorably cooperated with each other to play a role in resisting aging, and the anti-aging effect of the anti-aging composition is more remarkable and takes effect more quickly.
The invention is further configured to: the paint also comprises the following components in parts by mass:
8-15 parts of desmodium extract.
By adopting the technical scheme, the herba lysimachiae extract is added, so that the synergistic cooperation of the maritime pine bark extract, the bletilla striata root extract and the polygonum multiflorum extract is favorably promoted, the absorption of effective components in the anti-aging composition by a human body is favorably promoted, free radicals are favorably eliminated, and the anti-aging effect of the anti-aging composition is better and quicker.
The invention is further configured to: the paint also comprises the following components in parts by mass:
37-10 parts of ceramide.
By adopting the technical scheme, the ceramide 3 and the lysimachia christinae hance extract are added to be matched with each other in a synergistic manner, so that the promoting effect of the lysimachia christinae hance extract is favorably improved, the maritime pine bark extract, the bletilla striata root extract and the polygonum multiflorum extract are favorably matched with each other in a synergistic manner, the absorption of effective components in the anti-aging composition by a human body is favorably promoted, free radicals are favorably removed, meanwhile, the elasticity and the skin firmness of the skin are favorably improved, the wrinkles of the skin are fewer, the problem of the skin is better solved from the root source, the anti-aging effect of the anti-aging composition is favorably improved, and the anti-aging effect of the anti-aging composition is quicker to take effect.
The invention is further configured to: the paint also comprises the following components in parts by mass:
9-16 parts of ceramide 6 II.
By adopting the technical scheme, the ceramide 6 II, the lysimachia christinae hance extract and the ceramide 3 are added to be matched with each other in a synergistic manner, so that the promoting effects of the lysimachia christinae hance extract and the ceramide 3 are favorably and better improved, the maritime pine bark extract, the bletilla striata root extract and the polygonum multiflorum extract are favorably and mutually matched with each other in a synergistic manner, the effective components in the anti-aging composition are favorably absorbed by a human body better, the elasticity and the firmness of the skin are favorably and better improved, the wrinkles of the skin are fewer, the wrinkles of the skin are favorably and better solved from the root, and the anti-aging effect of the anti-aging composition is more remarkable and takes.
The invention is further configured to: the paint also comprises the following components in parts by mass:
10-13 parts of bis-diethoxydiol cyclohexane 1, 4-dicarboxylic ester.
By adopting the technical scheme, the bis-diethoxydiol cyclohexane 1, 4-dicarboxylate is added, so that the moisturizing effect of the anti-aging composition is enhanced, the skin moisture is supplemented better, the elasticity and the skin firmness of the skin are improved better, the wrinkles of the skin are fewer, the wrinkle problem is solved better from the root, and the anti-aging effect of the anti-aging composition is better and takes effect more quickly.
In order to achieve the second object, the invention provides the following technical scheme:
a preparation method of an anti-aging composition comprises the steps of stirring and uniformly mixing all components of the anti-aging composition according to the mass part ratio to obtain the anti-aging composition.
By adopting the technical scheme, the anti-aging composition can be obtained by uniformly stirring and mixing the components of the anti-aging composition according to the mass part ratio, the production is convenient and simple, the production conditions are easy to meet, the industrial production is facilitated, and the economic value of the anti-aging composition is higher.
In order to achieve the third object, the invention provides the following technical solutions:
the application of an anti-aging composition is to add the anti-aging composition into a skin care product.
By adopting the technical scheme, the anti-aging composition is added into the skin care product, so that the skin care product has an anti-aging function, the use method is simple and convenient, the application range is wide, and the economic value of the anti-aging composition is favorably improved.
The invention is further configured to: the skin care product comprises water, lotion, essence, cream, face cream and facial mask.
By adopting the technical scheme, the anti-aging composition is suitable for various skin care products such as water, emulsion, essence, cream, facial mask and the like, has wide application range, is favorable for better meeting the market requirement, and has higher market economic value.
The invention is further configured to: the addition mass of the anti-aging composition is 8-15% of the mass of the skin care product.
By adopting the technical scheme, the anti-aging composition can better exert the effect by controlling the addition quality of the anti-aging composition, so that the skin care product added with the anti-aging composition has better anti-aging effect and quicker response.
In conclusion, the invention has the following beneficial effects:
1. the maritime pine bark extract, the bletilla striata root extract and the polygonum multiflorum extract are matched in a synergistic manner, so that the absorption of effective components in the anti-aging composition by a human body is favorably promoted, free radicals are favorably eliminated better, the skin aging speed is favorably delayed better, the anti-aging effect of the anti-aging composition is more remarkable, and the effect is quicker;
2. the maritime pine bark extract, the bletilla striata root extract and the polygonum multiflorum extract are matched in a synergistic manner, so that the elasticity of the skin is improved better, the skin tightness is improved, skin wrinkles are reduced better, the wrinkle problem is solved better from the source, and the anti-aging effect of the anti-aging composition is more continuous;
3. the herba lysimachiae extract, the ceramide 3 and the ceramide 6 II are added, so that the synergistic cooperation of the maritime pine bark extract, the bletilla striata root extract and the polygonum multiflorum extract is favorably promoted, the absorption of effective components in the anti-aging composition by a human body is favorably promoted, free radicals are favorably eliminated, and the anti-aging effect of the anti-aging composition is better and quicker.
Drawings
FIG. 1 is a process flow diagram of the preparation method of the anti-aging composition of the present invention.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and examples.
In the following examples, the maritime pine bark extract was obtained from the swiss haying research ltd.
In the following examples, bletilla striata root extract was obtained from Guangzhou Ruan Bio-technology Ltd.
In the following examples, Polygoni Multiflori radix extract was obtained from Guangzhou Ruan biological science and technology Ltd.
In the following examples, ethanol from xian chun international trade (shanghai) ltd was used.
In the following examples, isopropyl alcohol was obtained from xian chun international trade (shanghai) ltd.
In the following examples, propylene glycol was obtained from Xianchuan International trade (Shanghai) Co.
In the following examples, the Lysimachia christinae extract was obtained from the Guangzhou Ruan scientific and biological Co.
In the following examples, ceramide 3 of the winning Industrial group was used as ceramide 3.
In the following examples, ceramide 6 II from the winning Industrial group was used as ceramide 6 II.
In the following examples, bis-diethoxydiol cyclohexane 1, 4-dicarboxylate was used from Japanese Kogyo Co., Ltd.
Example 1
The preparation method of the anti-aging composition comprises the following steps:
adding 17kg of solvent into a 150L stirring kettle at normal temperature, stirring at 220r/min, adding 22.5kg of maritime pine bark extract, 15kg of rhizoma Bletillae root extract and 12kg of Polygoni Multiflori radix extract while stirring, and stirring to obtain antiaging composition.
In this example, the solvent is ethanol.
Example 2
The difference from example 1 is that:
the amounts of the components added were as follows:
25kg of solvent; 20kg of maritime pine bark extract; 10kg of bletilla striata root extract; 10kg of polygonum multiflorum extract.
Example 3
The difference from example 1 is that:
the amounts of the components added were as follows:
21kg of solvent; 25kg of maritime pine bark extract; 12.5kg of bletilla striata root extract; 8kg of polygonum multiflorum extract.
Example 4
The difference from example 1 is that:
the amounts of the components added were as follows:
20kg of solvent; 24kg of maritime pine bark extract; 11kg of bletilla striata root extract; 11kg of polygonum multiflorum extract.
Example 5
The difference from example 4 is that: the solvent is isopropanol.
Example 6
The difference from example 4 is that: the solvent is propylene glycol.
Example 7
The difference from example 4 is that: 8kg of herba Lysimachiae Christinae extract was also added into the stirring kettle.
Example 8
The difference from example 4 is; the stirred tank was also charged with 15kg of herba Lysimachiae Christinae extract.
Example 9
The difference from example 4 is that: 37kg of ceramide was also added to the stirred tank.
Example 10
The difference from example 4 is that: also, 310kg of ceramide was added to the stirred tank.
Example 11
The difference from example 4 is that: the stirred tank was also charged with 9kg of ceramide 6 II.
Example 12
The difference from example 4 is that: 16kg of ceramide 6 II was also added to the stirred tank.
Example 13
The difference from example 4 is that: 8kg of herba Lysimachiae Christinae extract and 310kg of ceramide are also added into the stirring kettle.
Example 14
The difference from example 4 is that: the stirring kettle is also added with 15kg of desmodium extract and 37kg of ceramide.
Example 15
The difference from example 4 is that: 8kg of herba Lysimachiae Christinae extract, 310kg of ceramide and 6 II 9kg of ceramide are also added into the stirring kettle.
Example 16
The difference from example 4 is that: 15kg of herba Lysimachiae Christinae extract, 37kg of ceramide and 6 II 16kg of ceramide are also added into the stirring kettle.
Example 17
The difference from example 4 is that: also, 10kg of bis-diethoxydiol cyclohexane 1, 4-dicarboxylate was added to the stirred tank.
Example 18
The difference from example 4 is that: 13kg of bis-diethoxydiol cyclohexane 1, 4-dicarboxylate was also added to the stirred tank.
Example 19
The difference from example 4 is that:
the solvent is propylene glycol.
8kg of herba Lysimachiae Christinae extract, 310kg of ceramide, 6 II 16kg of ceramide and 10kg of bis-diethoxydiethylene glycol cyclohexane 1, 4-dicarboxylate were also added into the stirring kettle.
Example 20
The difference from example 17 is that:
the amounts of the components added were as follows:
11.5kg of desmodium extract, 37kg of ceramide, 12.5kg of ceramide 6 II and 13kg of bis-diethoxydiol cyclohexane 1, 4-dicarboxylate.
Example 21
The difference from example 17 is that:
the amounts of the components added were as follows:
15kg of desmodium extract, 38.5 kg of ceramide, 6 II 9kg of ceramide and 11.5kg of bis-diethoxydiol cyclohexane 1, 4-dicarboxylic ester.
Example 22
The difference from example 17 is that:
the amounts of the components added were as follows:
10kg of desmodium extract, 39 kg of ceramide, 6 II 13kg of ceramide and 12kg of bis-diethoxydiol cyclohexane 1, 4-dicarboxylic ester.
Comparative example 1
The difference from example 4 is that: the composition maritime pine bark extract was not added to the stirred tank.
Comparative example 2
The difference from example 4 is that: the bletilla striata root extract is not added into the stirring kettle.
Comparative example 3
The difference from example 4 is that: the polygonum multiflorum extract component is not added into the stirring kettle.
Experimental group 1
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the example 1 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and stirring and mixing uniformly to obtain the skin lotion with the anti-aging effect.
Experimental group 2
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the embodiment 2 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 3
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the embodiment 3 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and stirring and mixing uniformly to obtain the skin lotion with the anti-aging effect.
Experimental group 4
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the embodiment 4 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and stirring and mixing uniformly to obtain the skin lotion with the anti-aging effect.
Experimental group 5
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the example 5 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 6
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the embodiment 6 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 7
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the embodiment 7 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 8
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the embodiment 8 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 9
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the example 9 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and stirring and mixing uniformly to obtain the skin lotion with the anti-aging effect.
Experimental group 10
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the embodiment 10 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 11
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the example 11 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 12
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the example 12 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 13
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the example 13 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 14
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the example 14 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 15
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the embodiment 15 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 16
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the example 16 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 17
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the embodiment 17 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 18
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the example 18 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 19
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the example 19 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and stirring and mixing uniformly to obtain the skin lotion with the anti-aging effect.
Experimental group 20
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the embodiment 20 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Experimental group 21
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the example 21 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and stirring and mixing uniformly to obtain the skin lotion with the anti-aging effect.
Experimental group 22
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the example 22 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and stirring and mixing uniformly to obtain the skin lotion with the anti-aging effect.
Control group 1
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the comparative example 1 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Control group 2
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the comparative example 2 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Control group 3
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 10 percent of the anti-aging composition prepared in the comparative example 3 into 200mL of skin lotion, namely adding 20mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Control group 4
200mL of skin care water of a Beijing east self-office network shop of a flagship store with the hundred sparrows and the antelope horn is taken, 7 percent of the anti-aging composition prepared in the example 22 is added into the 200mL of skin care water, namely 14mL of the anti-aging composition is added, and the skin care water with the anti-aging effect is obtained by stirring and mixing uniformly.
Control group 5
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 16 percent of the anti-aging composition prepared in the example 22 into 200mL of skin lotion, namely adding 32mL of the anti-aging composition, and uniformly stirring and mixing to obtain the skin lotion with the anti-aging effect.
Control group 6
200mL of skin care water of a Beijing east self-office network shop of a flagship store with the hundred sparrows and the antelope horn is taken, 8 percent of the anti-aging composition prepared in the example 22 is added into the 200mL of skin care water, namely 16mL of the anti-aging composition is added, and the skin care water with the anti-aging effect is obtained by stirring and mixing uniformly.
Experimental group 7
Taking 200mL of skin lotion of the Beijing east self-office network shop of the flagship store of the hundred sparrows and the antelope horn, adding 15 percent of the anti-aging composition prepared in the example 22 into 200mL of skin lotion, namely adding 30mL of the anti-aging composition, and stirring and mixing uniformly to obtain the skin lotion with the anti-aging effect.
Blank group
200mL of skin care lotion of Beijing Ling flagship store, Jingdong self-operated official online shop is taken as a blank group without adding an anti-aging composition.
Experiment 1
Respectively taking 20mg of skin care water prepared from the experimental group, the control group and the blank group, dissolving the skin care water by using absolute ethyl alcohol, and fixing the volume to 250mL for later use; 20mg of 1, 1-diphenyl-2-trinitrophenylhydrazine (DPPH) is accurately weighed, dissolved by absolute ethyl alcohol and is added to a constant volume of 250mL for later use.
Placing 2mL of pre-prepared sample to be tested and 2mL of DPPH solution in a test tube, placing the test tube in a thermostat at 37 ℃ for 1h, taking absolute ethyl alcohol as a blank control, measuring the absorbance Ai of each sample to be tested at 517nm, calculating the clearance rate of free radicals, testing three groups of parallel samples for each sample to be tested, and calculating the average value.
The free radical clearance was calculated as: the radical clearance (%) [ (1- (Ai-Aj))/Ac ]. multidot.100%.
Wherein Ac is the absorbance of 2mL of absolute ethyl alcohol and 2mL of DPPH solution;
ai is the absorbance of 2mL of test agent plus 2mL of DPPH solution;
aj is the absorbance of 2mL of test agent plus 2mL of absolute ethanol solution.
Experiment 2
And randomly selecting 30 female volunteers from each group, wherein the age of the volunteers is 30-40 years, and the volunteers apply the anti-aging skin care water prepared by using the corresponding experimental group, the corresponding control group or the corresponding blank group every day to the cheeks, use the skin care water twice every day, use the skin care water once in the morning and at night, take 2mL every time, and insist use the skin care water for 30 days. Meanwhile, the skin lotion without the anti-aging composition is selected as a blank group, the following detection is carried out on the volunteers, and the average value of the detection results of all groups of volunteers is recorded.
Detection 1
The skin elasticity of the volunteers before and after the application of the skin lotion for 30 days was measured using a skin elasticity tester Corneometer MPA580 (wherein the larger the measurement value, the better the skin elasticity), and the change rate (%) of the skin elasticity was calculated and recorded. The rate of change of skin elasticity is calculated as: change rate (%) - (skin elasticity after skin lotion application-skin elasticity before skin lotion application)/skin elasticity before skin lotion application ]. 100%.
Detection 2
Skin firmness of the volunteers before and after applying the skin lotion for 30 days was measured using a skin elasticity tester Corneometer MPA580 (wherein the smaller the measured value, the more firm the skin was), and the rate of change (%) in skin firmness was calculated and recorded. The rate of change of skin firmness is calculated as: change (%) - ((skin firmness after skin lotion application-skin firmness before skin lotion application)/skin firmness before skin lotion application) 100%.
Detection 3
Skin wrinkles before and 30 days after the volunteers used the skin lotion were detected using the rapid three-dimensional imaging system PRIMOS for skin (wherein the smaller the detected value, the fewer the skin wrinkles), and the change rate (%) of the skin wrinkles was calculated and recorded. The rate of change of skin wrinkles was calculated as: change rate (%) - ((skin wrinkle after skin lotion application-skin wrinkle before skin lotion application)/skin wrinkle before skin lotion application) 100%.
The data from the above experiments are shown in Table 1.
TABLE 1
Figure BDA0002318200670000171
Figure BDA0002318200670000181
According to the comparison of the data of the experimental groups 4-6 in the table 1, the components in the anti-aging composition can be better dissolved by controlling the type of the solvent of the anti-aging composition, so that the components can better exert the synergistic effect, and the anti-aging effect of the anti-aging composition is better and faster.
According to the comparison of the data of the experimental group 4 and the experimental groups 7-14 in the table 1, the anti-aging composition can exert the effect better to a certain extent by independently adding the lysimachia christinae hance extract, the ceramide 3 or the ceramide 6 II, so that the anti-aging composition has better anti-aging effect and quicker response; the synergistic effect of the lysimachia christinae hance extract, the ceramide 3 and the ceramide 6 II is simultaneously added, so that the synergistic effect of the maritime pine bark extract, the bletilla striata root extract and the polygonum multiflorum extract is favorably promoted, the absorption of a human body to effective components is favorably promoted, and the anti-aging effect of the anti-aging composition is more remarkable and takes effect more quickly.
According to the comparison of the data of the experimental group 4 and the experimental groups 15-16 in the table 1, the addition of the bis-diethoxydiol cyclohexane 1, 4-dicarboxylate is beneficial to better supplement of skin moisture, so as to better improve the skin elasticity and the skin firmness, reduce skin wrinkles, and further improve the anti-aging effect and take effect of the anti-aging composition.
According to the comparison of the data of the experimental group 4 and the experimental groups 17-20 in the table 1, the anti-aging effect of the anti-aging composition can be better enhanced by adopting propylene glycol as a solvent and simultaneously adding the lysimachia christinae hance extract, the ceramide 3, the ceramide 6 II and the bis-diethoxydiol cyclohexane 1, 4-dicarboxylate to cooperate with each other synergistically, so that the anti-aging effect of the anti-aging composition is more remarkable and takes effect more quickly.
According to the comparison of the data of the experimental group 4 and the control groups 1-3 in table 1, the anti-aging effect of the anti-aging composition can be better improved only when the maritime pine bark extract, the bletilla striata root extract and the polygonum multiflorum extract are synergistically matched, and the anti-aging effect of the anti-aging composition is easily influenced if any one component is absent.
According to the comparison of the data of the experimental group 22 and the control groups 4-7 in the table 1, the anti-aging composition can better exert the effect by controlling the addition amount of the anti-aging composition added into the skin care product, so that the skin care product added with the anti-aging composition has better anti-aging effect and quicker effect.
The embodiments of the present invention are preferred embodiments of the present invention, and the scope of the present invention is not limited by these embodiments, so: all equivalent changes made according to the structure, shape and principle of the invention are covered by the protection scope of the invention.

Claims (10)

1. An anti-aging composition, which is characterized in that: the paint comprises the following components in parts by mass:
20-25 parts of maritime pine bark extract;
10-15 parts of bletilla striata root extract;
8-12 parts of polygonum multiflorum extract;
and 17-25 parts of a solvent.
2. The anti-aging composition according to claim 1, wherein: the solvent is propylene glycol.
3. The anti-aging composition according to claim 1, wherein: the paint also comprises the following components in parts by mass:
8-15 parts of desmodium extract.
4. The anti-aging composition according to claim 3, wherein: the paint also comprises the following components in parts by mass:
37-10 parts of ceramide.
5. The anti-aging composition according to claim 4, wherein: the paint also comprises the following components in parts by mass:
9-16 parts of ceramide 6 II.
6. The anti-aging composition according to any one of claims 1 to 5, which is characterized in that: the paint also comprises the following components in parts by mass:
10-13 parts of bis-diethoxydiol cyclohexane 1, 4-dicarboxylic ester.
7. A process for the preparation of an anti-ageing composition according to any one of claims 1 to 6, characterized in that: and stirring and uniformly mixing the components of the anti-aging composition according to the mass part ratio to obtain the anti-aging composition.
8. Use of an anti-ageing composition according to any one of claims 1 to 6, wherein: the anti-aging composition is added into a skin care product.
9. Use of an anti-ageing composition according to claim 8, characterized in that: the skin care product comprises water, lotion, essence, cream, face cream and facial mask.
10. Use of an anti-ageing composition according to claim 8, characterized in that: the addition mass of the anti-aging composition is 8-15% of the mass of the skin care product.
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